Page last updated: 2024-08-16

thalidomide and rolipram

thalidomide has been researched along with rolipram in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's8 (50.00)29.6817
2010's5 (31.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Chen, Y; Corral, LG; Muller, GW; Patterson, RT; Shire, MG; Stirling, DI; Wong, LM1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Jabaris, SS; Kodimuthali, A; Pal, M1
Hartmann, MD; Heim, C; Hernandez Alvarez, B; Maiwald, S1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Balk, KU; Byun, YS; Cho, JY; Lee, JH; Lee, SJ; Park, J; Park, JS; Park, MH; Son, HJ; Yoo, ES1
Eigler, A; Endres, S; Loher, F1
Abrahamsen, MS; Maheswaran, SK; Malazdrewich, C; Thumbikat, P1
Argilés, JM; Busquets, S; López-Soriano, FJ1
Brook, GA; Buss, A; Deumens, R; Geoghegan, L; Honig, WH; Joosten, EA; Kern, N; Koopmans, GC; Myint, AM; Noth, J1
Andrews, M; Brennan, FM; Feldmann, M; Inglis, JJ; McCann, FE; Palfreeman, AC; Perocheau, DP; Schafer, P; Williams, RO1
Carvalho, EM; Jesus, AR; Luna, T; Muniz, AL; Nascimento, M; Porto, MA; Santos, SB1
Goldminz, AM; Gottlieb, AB; Kim, N; Kumar, N1
Arias-Montaño, JA; Barragán-Ramírez, G; Fernández-Martínez, E; Mayén-García, C; Ortiz, MI; Ponce-Monter, H; Soria-Jasso, LE1
Bergmann, C; Beyer, C; Distler, JHW; Kittan, N; Maier, C; Ramming, A; Schett, G; Weinkam, R1

Reviews

4 review(s) available for thalidomide and rolipram

ArticleYear
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chronic Obstructive

2008
[Suppression of synthesis of tumor necrosis factor].
    Der Internist, 2001, Volume: 42, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; Crohn Disease; Humans; Inflammation; Interleukin-10; Phosphodiesterase Inhibitors; Rolipram; Signal Transduction; Thalidomide; Tumor Necrosis Factor-alpha

2001
The pivotal role of cytokines in muscle wasting during cancer.
    The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:10

    Topics: Animals; Anorexia; Antibodies; Cachexia; Cytokines; Humans; Models, Biological; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Pentoxifylline; Rolipram; Signal Transduction; Thalidomide; Transcription Factors

2005
Phosphodiesterase 4-targeted treatments for autoimmune diseases.
    BMC medicine, 2013, Apr-04, Volume: 11

    Topics: Autoimmune Diseases; Chronic Disease; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Phosphodiesterase 4 Inhibitors; Rolipram; Thalidomide

2013

Other Studies

12 other study(ies) available for thalidomide and rolipram

ArticleYear
Thalidomide analogs and PDE4 inhibition.
    Bioorganic & medicinal chemistry letters, 1998, Oct-06, Volume: 8, Issue:19

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Phosphodiesterase Inhibitors; Structure-Activity Relationship; Thalidomide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay.
    ACS medicinal chemistry letters, 2021, Jan-14, Volume: 12, Issue:1

    Topics:

2021
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Synthesis and structure-activity relationships of novel compounds for the inhibition of TNF-alpha production.
    Archives of pharmacal research, 2000, Volume: 23, Issue:4

    Topics: Animals; Mice; Models, Biological; Phosphodiesterase Inhibitors; Rolipram; Structure-Activity Relationship; Thalidomide; Tumor Necrosis Factor-alpha

2000
Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages.
    Microbial pathogenesis, 2004, Volume: 36, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Cytokines; Dexamethasone; Exotoxins; Gene Expression Regulation; Imidazoles; Interleukin-1; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Mannheimia haemolytica; Pentoxifylline; Pyridines; RNA, Messenger; Rolipram; Tetrahydropapaveroline; Thalidomide; Tumor Necrosis Factor-alpha

2004
Acute rolipram/thalidomide treatment improves tissue sparing and locomotion after experimental spinal cord injury.
    Experimental neurology, 2009, Volume: 216, Issue:2

    Topics: Animals; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Immunosuppressive Agents; Interleukin-1beta; Locomotion; Male; Myelin Basic Protein; Nerve Regeneration; Neurofilament Proteins; Phosphodiesterase Inhibitors; Psychomotor Performance; Rats; Rats, Inbred Lew; Recovery of Function; Rolipram; Spinal Cord Injuries; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha

2009
Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.
    Arthritis research & therapy, 2010, Volume: 12, Issue:3

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rolipram; Severity of Illness Index; Synovial Membrane; Thalidomide; Tumor Necrosis Factor-alpha

2010
Effect of TNF-α production inhibitors on the production of pro-inflammatory cytokines by peripheral blood mononuclear cells from HTLV-1-infected individuals.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:11

    Topics: Anti-Inflammatory Agents; Case-Control Studies; Colforsin; Female; HTLV-I Infections; Humans; Immunosuppressive Agents; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Pentoxifylline; Rolipram; Statistics, Nonparametric; Thalidomide; Tumor Necrosis Factor-alpha

2011
Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade.
    Molecules (Basel, Switzerland), 2016, Oct-07, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Models, Biological; Muscle Contraction; Myometrium; Phosphodiesterase 4 Inhibitors; Potassium; Pregnancy; Rolipram; Thalidomide; Young Adult

2016
Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:6

    Topics: Animals; Bleomycin; Cell Differentiation; Collagen; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytokines; Disease Models, Animal; DNA Topoisomerases, Type I; Fibroblasts; Fibrosis; Gene Expression; Graft vs Host Disease; Humans; Interleukin-13; Interleukin-6; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phosphodiesterase 4 Inhibitors; RNA, Messenger; Rolipram; Scleroderma, Systemic; Skin; Thalidomide; Transforming Growth Factor beta1; Transforming Growth Factor beta2

2017