Page last updated: 2024-08-16

thalidomide and pentoxifylline

thalidomide has been researched along with pentoxifylline in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (26.15)	18.2507
2000's	32 (49.23)	29.6817
2010's	12 (18.46)	24.3611
2020's	4 (6.15)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Bartlett, R; Fazal, N; Kumararatne, DS; Lammas, DA; Raykundalia, C	1
Bemelmans, M; Blok, WL; Buurman, WA; Kullberg, BJ; Netea, MG; van der Meer, JW; Vogels, MT	1
Frindt, P; Kaplan, G; Moreira, AL; Sampaio, EP; Smith, KA; Zmuidzinas, A	1
Breedveld, FC; Dijkmans, BA; Huizinga, TW; van de Pouw Kraan, TC; van der Velde, EA; Verweij, CL	1
Abalos, RM; Balagon, MV; Cellona, RV; Fajardo, TJ; Kaplan, G; Moreira, AL; Tan, EV; Villahermosa, LG; Walsh, GP	1
Haslett, PA	1
Wanke, C	1
Lacosta Nicolás, JL; Martínez Iñiguez, JC	1
Baguley, BC; Browne, WL; Ching, LM; Gregory, T; Palmer, BD; Tchernegovski, R	1
Stambe, C; Wicks, IP	1
Bala, S; Dempsey, WL; Hastings, KL; Inglis, S; Kazempour, K	1
Isaacs, JT; Joseph, IB	1
Fandrey, J; Jelkmann, W; Wördemann, M	1
Toussirot, E; Wendling, D	1
Arrieta, O; Calvillo, M; Ortiz-Reyes, A; Rembao, D; Rivera, E; Sotelo, J	1
Verougstraete, C	1
Brenner, T; Gallily, R; Kipper-Galperin, M	1
Raza, A	1
Kullberg, BJ; Netea, MG; van Crevel, R; van der Meer, JW; Vonk, AG	1
Kaklamani, VG; Kaklamanis, PG	1
Carneiro-Filho, BA; Lima, AA; Ribeiro, RA; Souza, ML	1
Blam, ME; Lichtenstein, GR; Stein, RB	1
Akhter, S; Ambrus, JL; Karakousis, CP; Kulaylat, M; Plavsic, L; Toumbis, CA	1
Fabrizio, P; Finch, CE; Han, D; Longo, VD; Morgan, TE; Wei, M; Xie, Z	1
Brito, GA; Carneiro-Filho, BA; Cunha, FQ; Lima, AA; Melo, DH; Michelin, MA; Ribeiro, RA; Viana, CF	1
Geraldo, NT; Moraes, MO; Salles, AM; Sampaio, EP; Sarno, EN; Teles, RM	1
Mann, DL	2
Moller, DR	1
Austin, AS; Clarke, D; Freeman, JG; Mahida, YR; Ryder, SD	1
Abrahamsen, MS; Maheswaran, SK; Malazdrewich, C; Thumbikat, P	1
Brito, GA; Lima, V; Ribeiro, RA; Rocha, FA; Vidal, FD	1
Achirafi, A; de Carsalade, GY; Flageul, B	1
Hasan, Z; Hussain, R; Thakurdas, SM	1
Korzenik, JR	1
Almeida, AC; Bezerra, G; Fonteles, MC; Lima, AA; Martins, AM; Monteiro, HS; Nobre, AC	1
Alexandre-Moreira, MS; Barreiro, EJ; Castro Faria Neto, HC; de Arruda, LB; Gomes, RN; Lima, LM; Pascarelli, B; Takiya, CM	1
Augusto, RF; Brito, GA; Cunha, FQ; Falcão, BA; Leitão, BT; Lima, V; Rebouças, CG; Ribeiro, RA; Souza, ML	1
Goupille, P; Griffoul, I; Mammou, S; Mulleman, D; Watier, H	1
Argilés, JM; Busquets, S; López-Soriano, FJ	1
Aukrust, P; Damås, JK; Gullestad, L; Ueland, T; Yndestad, A	1
Badgwell, C; Rosen, T	1
de Matos, HJ; Duppre, NC; Nery, JA; Sales, AM; Sampaio, EP; Sarno, EN	1
Brito, GA; Carvalho, SB; Cunha, FQ; Melo, ML; Ribeiro, RA; Silva, JV; Soares, PM; Soares, RC; Souza, MH; Vale, ML	1
Almeida, PR; Baltazar, F; Brito, GA; Ferreira, FV; Macedo, FY; Ribeiro, RA; Schmitt, FC; Távora, F	1
Lockwood, DN; Walker, SL; Waters, MF	1
Hirota, SK; Migliari, DA; Mimura, MA; Sanches, JA; Sugaya, NN	1
Antoniu, SA	1
Aarestrup, BJ; Aarestrup, FM; Corrêa, JO	1
Alarcón-Galván, G; Cámara-Lemarroy, CR; Cordero-Pérez, P; Fernández-Garza, NE; Guzmán-de la Garza, FJ; Muñoz-Espinosa, LE	1
Bargagli, E; Olivieri, C; Rottoli, P	1
Carvalho, EM; Jesus, AR; Luna, T; Muniz, AL; Nascimento, M; Porto, MA; Santos, SB	1
Kremer, AE; Mettang, T	1
Borghi, SM; Carvalho, TT; Casagrande, R; Cunha, FQ; Cunha, TM; Ferreira, SH; Mizokami, SS; Pinho-Ribeiro, FA; Verri, WA	1
Costa, PDSS; Daxbacher, ELR; Fraga, LR; Kowalski, TW; Schuler-Faccini, L; Vianna, FSL	1
Prado, BL; Qian, Y	1
Almeida, DF; Cavalcante, RS; Dos Santos, AR; Finato, AC; Mendes, RP; Nascimento, DC; Paniago, AMM; Soares, CT; Venturini, J	1
Barroso, DH; Bezerra, NVF; Cerqueira, SRPS; Collin, SM; Cunha, DV; Deps, PD; Gomes, CM; Kurizky, PS; Pillegi, GS; Pinheiro, ABS; Repsold, TAR	1
Duvic, M; Joshi, TP	1

Reviews

22 review(s) available for thalidomide and pentoxifylline

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Anticytokine approaches to the treatment of anorexia and cachexia. Seminars in oncology, 1998, Volume: 25, Issue:2 Suppl 6 Topics: Anorexia; Cachexia; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Pentoxifylline; Phosphodiesterase Inhibitors; Thalidomide; Tumor Necrosis Factor-alpha; Wasting Syndrome	1998
Single-agent/combination therapy of human immunodeficiency virus-related wasting. Seminars in oncology, 1998, Volume: 25, Issue:2 Suppl 6 Topics: Anabolic Agents; Androgens; Appetite Stimulants; Drug Therapy, Combination; Growth Hormone; HIV Wasting Syndrome; Humans; Pentoxifylline; Thalidomide	1998
[Treatment of recurrent aphthous stomatitis. A bibliographic review]. Revista clinica espanola, 1998, Volume: 198, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Calcium Phosphates; Dinoprostone; Female; Glycopeptides; Humans; Immunologic Factors; Immunosuppressive Agents; Interferons; Male; Oxytocics; Pentoxifylline; Phosphodiesterase Inhibitors; Recurrence; Stomatitis, Aphthous; Thalidomide	1998
[Present and future treatment of age-related macular degeneration]. Bulletin de la Societe belge d'ophtalmologie, 1999, Volume: 273 Topics: Animals; Clinical Trials as Topic; Diet Therapy; Forecasting; Humans; Interferon alpha-2; Interferon-alpha; Light Coagulation; Macular Degeneration; Neovascularization, Pathologic; Pentoxifylline; Photochemotherapy; Recombinant Proteins; Retina; Thalidomide	1999
Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes. Microscopy research and technique, 2000, Aug-01, Volume: 50, Issue:3 Topics: Arthritis, Rheumatoid; Crohn Disease; Etanercept; Humans; Immunoglobulin G; Myelodysplastic Syndromes; Pentoxifylline; Receptors, Tumor Necrosis Factor; Sepsis; Thalidomide; Tumor Necrosis Factor-alpha	2000
Integrating anti-tumor necrosis factor therapy in inflammatory bowel disease: current and future perspectives. The American journal of gastroenterology, 2001, Volume: 96, Issue:7 Topics: Animals; Antibodies, Monoclonal; Clinical Trials as Topic; Etanercept; Forecasting; Gastrointestinal Agents; Humans; Immunoglobulin G; Inflammatory Bowel Diseases; Infliximab; Models, Biological; Pentoxifylline; Receptors, Tumor Necrosis Factor; Thalidomide; Tumor Necrosis Factor-alpha	2001
Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circulation research, 2002, Nov-29, Volume: 91, Issue:11 Topics: Animals; Antibodies, Monoclonal; Antirheumatic Agents; Clinical Trials as Topic; Cytokines; Disease Progression; Endothelium, Vascular; Etanercept; Heart Failure; Humans; Immunoglobulin G; Immunologic Factors; Inflammation Mediators; Infliximab; Pentoxifylline; Receptors, Tumor Necrosis Factor; Research; Thalidomide; Treatment Failure; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left	2002
Treatment of sarcoidosis -- from a basic science point of view. Journal of internal medicine, 2003, Volume: 253, Issue:1 Topics: Etanercept; Granuloma; Humans; Immunoglobulin G; Immunosuppressive Agents; Interleukins; Pentoxifylline; Phosphodiesterase Inhibitors; Receptors, Tumor Necrosis Factor; Sarcoidosis; Thalidomide; Tumor Necrosis Factor-alpha	2003
Crohn's disease: future anti-tumor necrosis factor therapies beyond infliximab. Gastroenterology clinics of North America, 2004, Volume: 33, Issue:2 Topics: Antibodies, Monoclonal; Crohn Disease; Etanercept; Humans; Immunoglobulin G; Immunosuppressive Agents; Infliximab; Pentoxifylline; Receptors, Tumor Necrosis Factor; Thalidomide; Tumor Necrosis Factor-alpha	2004
Pathophysiology of disk-related low back pain and sciatica. II. Evidence supporting treatment with TNF-alpha antagonists. Joint bone spine, 2006, Volume: 73, Issue:3 Topics: Animals; Antibodies, Monoclonal; Doxycycline; Humans; Infliximab; Low Back Pain; Neuralgia; Pentoxifylline; Randomized Controlled Trials as Topic; Rats; Sciatica; Spinal Nerve Roots; Thalidomide; Tumor Necrosis Factor-alpha	2006
The pivotal role of cytokines in muscle wasting during cancer. The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:10 Topics: Animals; Anorexia; Antibodies; Cachexia; Cytokines; Humans; Models, Biological; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Pentoxifylline; Rolipram; Signal Transduction; Thalidomide; Transcription Factors	2005
Anti-inflammatory trials in chronic heart failure. Heart failure monitor, 2006, Volume: 5, Issue:1 Topics: Adult; Aged; Animals; Cytokines; Female; Free Radical Scavengers; Heart Failure; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Immunosorbents; Immunosuppressive Agents; Inflammation Mediators; Male; Middle Aged; Pentoxifylline; Randomized Controlled Trials as Topic; Thalidomide; Treatment Outcome	2006
Cutaneous sarcoidosis therapy updated. Journal of the American Academy of Dermatology, 2007, Volume: 56, Issue:1 Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigen Presentation; Antimalarials; Chlorambucil; Contraindications; Cyclosporine; Cytokines; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infliximab; Isoxazoles; Laser Therapy; Leflunomide; Male; Melatonin; Methotrexate; Models, Immunological; Pentoxifylline; Pregnancy; Pregnancy Complications; Sarcoidosis; Skin Diseases; Tetracyclines; Th1 Cells; Thalidomide	2007
The role of thalidomide in the management of erythema nodosum leprosum. Leprosy review, 2007, Volume: 78, Issue:3 Topics: Aspirin; Controlled Clinical Trials as Topic; Decision Trees; Erythema Nodosum; Humans; Leprostatic Agents; Pentoxifylline; Thalidomide	2007
Targeting the TNF-alpha pathway in sarcoidosis. Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:1 Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Etanercept; Humans; Immunoglobulin G; Infliximab; Pentoxifylline; Receptors, Tumor Necrosis Factor; Sarcoidosis; Signal Transduction; Thalidomide; Tumor Necrosis Factor-alpha	2010
Cytokine modulators in the treatment of sarcoidosis. Rheumatology international, 2011, Volume: 31, Issue:12 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Cytokines; Humans; Immunologic Factors; Immunosuppressive Agents; Pentoxifylline; Rituximab; Sarcoidosis, Pulmonary; Thalidomide; Tumor Necrosis Factor-alpha; Ustekinumab	2011
Uremic pruritus. Kidney international, 2015, Volume: 87, Issue:4 Topics: Acupuncture Therapy; Amines; Anti-Inflammatory Agents; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; gamma-Linolenic Acid; Humans; Morphinans; Naltrexone; Narcotic Antagonists; Pentoxifylline; Phototherapy; Pregabalin; Pruritus; Receptors, Opioid, kappa; Renal Insufficiency, Chronic; Spiro Compounds; Tacrolimus; Thalidomide; Uremia	2015
Innate immunity and the failing heart: the cytokine hypothesis revisited. Circulation research, 2015, Mar-27, Volume: 116, Issue:7 Topics: Adaptive Immunity; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; Biomarkers; Clinical Trials, Phase III as Topic; Cytokines; Dexamethasone; Heart Failure; Humans; Immunity, Innate; Immunologic Factors; Immunosuppressive Agents; Inflammation; Models, Cardiovascular; Models, Immunological; Pentoxifylline; Randomized Controlled Trials as Topic; Receptors, Pattern Recognition; Signal Transduction; Thalidomide; Treatment Outcome; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Remodeling	2015
Erythema Nodosum Leprosum: Update and challenges on the treatment of a neglected condition. Acta tropica, 2018, Volume: 183 Topics: Anti-Inflammatory Agents; Erythema Nodosum; Glucocorticoids; Humans; Inflammation; Leprostatic Agents; Leprosy, Lepromatous; Neglected Diseases; Pentoxifylline; Recurrence; Remission Induction; Thalidomide; Treatment Outcome	2018
Anti-cytokines in the treatment of cancer cachexia. Annals of palliative medicine, 2019, Volume: 8, Issue:1 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cachexia; Cytokines; Etanercept; Forecasting; Humans; Immunosuppressive Agents; Infliximab; Melatonin; Neoplasms; Pentoxifylline; Thalidomide	2019
Granuloma Annulare: An Updated Review of Epidemiology, Pathogenesis, and Treatment Options. American journal of clinical dermatology, 2022, Volume: 23, Issue:1 Topics: Anti-Infective Agents; Antimalarials; Biological Therapy; Comorbidity; Dermatologic Agents; Diabetes Complications; Diagnosis, Differential; Glucocorticoids; Granuloma Annulare; Humans; Iatrogenic Disease; Infections; Methotrexate; Neoplasms; Pentoxifylline; Phosphodiesterase 4 Inhibitors; Phototherapy; Piperidines; Pyrimidines; Thalidomide	2022

Trials

4 trial(s) available for thalidomide and pentoxifylline

Article	Year
A pilot study to investigate the use of oxpentifylline (pentoxifylline) and thalidomide in portal hypertension secondary to alcoholic cirrhosis. Alimentary pharmacology & therapeutics, 2004, Jan-01, Volume: 19, Issue:1 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Pentoxifylline; Pilot Projects; Thalidomide; Tumor Necrosis Factor-alpha; Vasodilator Agents	2004
[Pentoxifylline in the treatment of erythema nodosum leprosum: results of an open study]. Acta leprologica, 2003, Volume: 12, Issue:3 Topics: Adolescent; Adult; Erythema Nodosum; Female; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Leprostatic Agents; Leprosy, Lepromatous; Male; Neuralgia; Pentoxifylline; Prednisone; Recurrence; Remission Induction; Safety; Thalidomide; Treatment Outcome; Tumor Necrosis Factor-alpha	2003
Double-blind trial of the efficacy of pentoxifylline vs thalidomide for the treatment of type II reaction in leprosy. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2007, Volume: 40, Issue:2 Topics: Adolescent; Adult; Double-Blind Method; Erythema Nodosum; Female; Humans; Leprostatic Agents; Leprosy, Lepromatous; Male; Middle Aged; Pentoxifylline; Thalidomide; Treatment Outcome	2007
Systemic treatment in severe cases of recurrent aphthous stomatitis: an open trial. Clinics (Sao Paulo, Brazil), 2009, Volume: 64, Issue:3 Topics: Adolescent; Adult; Aged; Child; Colchicine; Dapsone; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pentoxifylline; Recurrence; Severity of Illness Index; Stomatitis, Aphthous; Thalidomide; Treatment Outcome; Young Adult	2009

Other Studies

39 other study(ies) available for thalidomide and pentoxifylline

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Effect of blocking TNF-alpha on intracellular BCG (Bacillus Calmette Guerin) growth in human monocyte-derived macrophages. FEMS microbiology immunology, 1992, Volume: 5, Issue:5-6 Topics: Antibodies; Cells, Cultured; Dexamethasone; Humans; Macrophages; Mycobacterium bovis; Pentoxifylline; Thalidomide; Tumor Necrosis Factor-alpha	1992
Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice. The Journal of infectious diseases, 1995, Volume: 171, Issue:2 Topics: Animals; Candidiasis; Chlorpromazine; Female; Interleukin-1; Kidney; Klebsiella Infections; Klebsiella pneumoniae; Mice; Neutropenia; Pentoxifylline; Receptors, Tumor Necrosis Factor; Shock, Septic; Thalidomide; Tumor Necrosis Factor-alpha	1995
Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. The Journal of experimental medicine, 1993, Jun-01, Volume: 177, Issue:6 Topics: Animals; Cells, Cultured; Dexamethasone; Humans; Monocytes; Pentoxifylline; RNA, Messenger; Sheep; Thalidomide; Tumor Necrosis Factor-alpha	1993
An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis. Annals of the rheumatic diseases, 1996, Volume: 55, Issue:11 Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemotherapy, Adjuvant; Hematologic Tests; Humans; Immunosuppressive Agents; Interleukin-10; Interleukin-12; Interleukin-6; Middle Aged; Pentoxifylline; Severity of Illness Index; Thalidomide; Tumor Necrosis Factor-alpha	1996
Comparison of pentoxifylline, thalidomide and prednisone in the treatment of ENL. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1998, Volume: 66, Issue:1 Topics: Adolescent; Adult; Cytokines; Erythema Nodosum; Female; Humans; Leprosy, Lepromatous; Male; Pentoxifylline; Prednisone; Receptors, Cytokine; Thalidomide	1998
Interaction of thalidomide, phthalimide analogues of thalidomide and pentoxifylline with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid: concomitant reduction of serum tumour necrosis factor-alpha and enhancement of anti-tumour activity. British journal of cancer, 1998, Volume: 78, Issue:3 Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Synergism; Mice; Neoplasm Transplantation; Pentoxifylline; Phthalimides; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones	1998
TNFalpha and response of treatment-resistant adult-onset Still's disease to thalidomide. Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127 Topics: Adult; Case-Control Studies; Drug Resistance; Female; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Pentoxifylline; Phosphodiesterase Inhibitors; Remission Induction; Still's Disease, Adult-Onset; Thalidomide; Tumor Necrosis Factor-alpha	1998
Inhibition of tumor necrosis factor alpha alters resistance to Mycobacterium avium complex infection in mice. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9 Topics: Animals; Dexamethasone; Female; Mice; Mice, Inbred C57BL; Mycobacterium avium; Pentoxifylline; Thalidomide; Tuberculosis; Tumor Necrosis Factor-alpha	1998
Macrophage role in the anti-prostate cancer response to one class of antiangiogenic agents. Journal of the National Cancer Institute, 1998, Nov-04, Volume: 90, Issue:21 Topics: Animals; Antineoplastic Agents; Enzyme-Linked Immunosorbent Assay; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyquinolines; Macrophages; Male; Mice; Neovascularization, Pathologic; Pentoxifylline; Prostatic Neoplasms; Rats; Thalidomide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1998
Tumor necrosis factor-alpha production by human hepatoma cell lines is resistant to drugs that are inhibitory to macrophages. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 1998, Volume: 18, Issue:12 Topics: Adjuvants, Immunologic; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Macrophages; Pentoxifylline; Pregnanes; Taurine; Thalidomide; Thiadiazines; Tumor Necrosis Factor-alpha	1998
TNF-alpha-targeted therapy in rheumatoid arthritis. Revue du rhumatisme (English ed.), 1999, Volume: 66, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis, Rheumatoid; Drug Therapy, Combination; Etanercept; Humans; Immunoglobulin G; Immunoglobulin gamma-Chains; Immunoglobulin Heavy Chains; Mice; Pentoxifylline; Rats; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Thalidomide; Tumor Necrosis Factor-alpha	1999
Protective effect of pentoxifylline plus thalidomide against septic shock in mice. International journal of experimental pathology, 1999, Volume: 80, Issue:1 Topics: Animals; Drug Therapy, Combination; Immunosuppressive Agents; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Pentoxifylline; Platelet Aggregation Inhibitors; Shock, Septic; Survival Rate; Thalidomide	1999
Mycoplasma fermentans-induced inflammatory response of astrocytes: selective modulation by aminoguanidine, thalidomide, pentoxifylline and IL-10. Inflammation, 1999, Volume: 23, Issue:6 Topics: Animals; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Guanidines; Inflammation; Interleukin-10; Mycoplasma fermentans; Mycoplasma Infections; Pentoxifylline; Rats; Rats, Inbred Lew; Thalidomide	1999
Modulation of LPS-, PHA- and M. tuberculosis-mediated cytokine production by pentoxifylline and thalidomide. European cytokine network, 2000, Volume: 11, Issue:4 Topics: Cells, Cultured; Cytokines; Drug Interactions; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocyte Activation; Mycobacterium tuberculosis; Pentoxifylline; Phytohemagglutinins; Thalidomide	2000
Treatment of Behçet's disease--an update. Seminars in arthritis and rheumatism, 2001, Volume: 30, Issue:5 Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Behcet Syndrome; Chlorambucil; Colchicine; Cyclophosphamide; Cyclosporine; Dapsone; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferons; Levamisole; Male; Methotrexate; Pentoxifylline; Recombinant Proteins; Recurrence; Sulfasalazine; Thalidomide	2001
The effect of tumour necrosis factor (TNF) inhibitors in Clostridium difficile toxin-induced paw oedema and neutrophil migration. Pharmacology & toxicology, 2001, Volume: 88, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Botulinum Toxins; Botulinum Toxins, Type A; Chemotaxis, Leukocyte; Clostridioides difficile; Dermatologic Agents; Edema; Enzyme Inhibitors; Male; Neutrophils; Pentoxifylline; Rats; Rats, Wistar; Thalidomide; Tumor Necrosis Factor-alpha	2001
Study of antiangiogenic agents with possible therapeutic applications in neoplastic disorders and macular degeneration. Journal of medicine, 2000, Volume: 31, Issue:5-6 Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Cornea; Corneal Neovascularization; Drug Combinations; Enzyme Inhibitors; Humans; Keratinocytes; Macaca; Macular Degeneration; Melanoma; Pentoxifylline; Thalidomide	2000
Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-01, Volume: 22, Issue:9 Topics: Amyloid beta-Peptides; Animals; Cell Separation; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Immunosuppressive Agents; Interferon-gamma; Iron Compounds; Lipopolysaccharides; Microglia; Neurons; Nitric Oxide Synthase; Pentoxifylline; Peptide Fragments; Peroxynitrous Acid; Rats; Rats, Inbred F344; Superoxides; Thalidomide; Tumor Necrosis Factor-alpha	2002
Pro-inflammatory effects of cholera toxin: role of tumor necrosis factor alpha. Toxicon : official journal of the International Society on Toxinology, 2002, Volume: 40, Issue:10 Topics: Animals; Cell Movement; Cholera Toxin; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hindlimb; Inflammation; Macrophages, Peritoneal; Male; Neutrophils; Pentoxifylline; Rats; Rats, Wistar; Thalidomide; Tumor Necrosis Factor-alpha; Vibrio cholerae	2002
Differential TNFalpha mRNA regulation detected in the epidermis of leprosy patients. Archives of dermatological research, 2002, Volume: 294, Issue:8 Topics: Adult; Aged; Anti-Inflammatory Agents; Cytokines; Dermis; Epidermis; Female; Humans; Intercellular Adhesion Molecule-1; Leprostatic Agents; Leprosy; Male; Middle Aged; Pentoxifylline; Prednisone; RNA, Messenger; Thalidomide; Tumor Necrosis Factor-alpha	2002
Pharmacological inhibition of Mannheimia haemolytica lipopolysaccharide and leukotoxin-induced cytokine expression in bovine alveolar macrophages. Microbial pathogenesis, 2004, Volume: 36, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Cytokines; Dexamethasone; Exotoxins; Gene Expression Regulation; Imidazoles; Interleukin-1; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Mannheimia haemolytica; Pentoxifylline; Pyridines; RNA, Messenger; Rolipram; Tetrahydropapaveroline; Thalidomide; Tumor Necrosis Factor-alpha	2004
Effects of tumor necrosis factor-alpha inhibitors pentoxifylline and thalidomide on alveolar bone loss in short-term experimental periodontal disease in rats. Journal of periodontology, 2004, Volume: 75, Issue:1 Topics: Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents; Ligation; Male; Pentoxifylline; Periodontitis; Rats; Rats, Wistar; Statistics, Nonparametric; Thalidomide; Tumor Necrosis Factor-alpha	2004
IgG1 antimycobacterial antibodies can reverse the inhibitory effect of pentoxifylline on tumour necrosis factor alpha (TNF-alpha) secreted by mycobacterial antigen-stimulated adherent cells. Clinical and experimental immunology, 2004, Volume: 136, Issue:2 Topics: Adult; Anti-Inflammatory Agents; Antibodies, Bacterial; Antigens, Bacterial; Cell Adhesion; Cells, Cultured; Female; Humans; Immunoglobulin G; Interleukin-10; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Mycobacterium tuberculosis; Pentoxifylline; Statistics, Nonparametric; Thalidomide; Tumor Necrosis Factor-alpha	2004
Thalidomide and pentoxifylline block the renal effects of supernatants of macrophages activated with Crotalus durissus cascavella venom. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2004, Volume: 37, Issue:10 Topics: Animals; Crotalid Venoms; Female; Immunosuppressive Agents; Kidney; Macrophage Activation; Macrophages, Peritoneal; Male; Pentoxifylline; Rats; Rats, Wistar; Thalidomide; Tumor Necrosis Factor-alpha	2004
LASSBio-468: a new achiral thalidomide analogue which modulates TNF-alpha and NO production and inhibits endotoxic shock and arthritis in an animal model. International immunopharmacology, 2005, Volume: 5, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Gene Expression; Indoles; Isoindoles; Lipopolysaccharides; Lymphocyte Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Pentoxifylline; Rats; Rats, Wistar; Shock, Septic; Thalidomide; Tumor Necrosis Factor-alpha; Vasculitis, Central Nervous System	2005
Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. European journal of oral sciences, 2005, Volume: 113, Issue:3 Topics: Abscess; Animals; Antimetabolites, Antineoplastic; Cricetinae; Disease Models, Animal; Edema; Erythema; Fluorouracil; Hemorrhage; Hyperemia; Immunosuppressive Agents; Leukocyte Count; Male; Mesocricetus; Mouth Mucosa; Neutrophils; Oral Ulcer; Pentoxifylline; Peroxidase; Protective Agents; Stomatitis; Thalidomide; Time Factors; Tumor Necrosis Factor-alpha	2005
Role of cytokines (TNF-alpha, IL-1beta and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide. Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemokines; Diarrhea; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Injections, Intraperitoneal; Interleukin-1beta; Intestine, Small; Irinotecan; Male; Mice; Mucositis; Pentoxifylline; Peroxidase; Thalidomide; Tumor Necrosis Factor-alpha	2008
Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:1 Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cystitis; Drug Therapy, Combination; Etoricoxib; Hemorrhage; Ifosfamide; Immunoenzyme Techniques; Indomethacin; Male; Mesna; Pentoxifylline; Protective Agents; Pyridines; Rats; Rats, Wistar; Sulfones; Thalidomide	2008
Effect of thalidomide and pentoxifylline on experimental autoimmune encephalomyelitis (EAE). Experimental neurology, 2010, Volume: 226, Issue:1 Topics: Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunosuppressive Agents; Interferon-gamma; Kinetics; Nerve Fibers; Nitric Oxide; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Thalidomide; Tumor Necrosis Factor-alpha	2010
Effects of thalidomide and pentoxyphylline over local and remote organ injury after intestinal ischemia/reperfusion. Transplantation proceedings, 2010, Volume: 42, Issue:5 Topics: Animals; Aspartate Aminotransferases; Enzyme-Linked Immunosorbent Assay; Intestinal Mucosa; Intestines; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Lung; Male; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Thalidomide; Tumor Necrosis Factor-alpha	2010
Effect of TNF-α production inhibitors on the production of pro-inflammatory cytokines by peripheral blood mononuclear cells from HTLV-1-infected individuals. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:11 Topics: Anti-Inflammatory Agents; Case-Control Studies; Colforsin; Female; HTLV-I Infections; Humans; Immunosuppressive Agents; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Pentoxifylline; Rolipram; Statistics, Nonparametric; Thalidomide; Tumor Necrosis Factor-alpha	2011
Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10. European journal of pharmacology, 2015, Feb-15, Volume: 749 Topics: Analgesics, Opioid; Animals; Etanercept; Granulocyte Colony-Stimulating Factor; Hyperalgesia; Immunoglobulin G; Interleukin 1 Receptor Antagonist Protein; Interleukin-10; Interleukin-1beta; Leukocyte Count; Mice, Inbred C57BL; Mice, Knockout; Morphine; Pentoxifylline; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Skin; Thalidomide; Tumor Necrosis Factor-alpha	2015
Evaluation of antifibrotic and antifungal combined therapies in experimental pulmonary paracoccidioidomycosis. Medical mycology, 2020, Jul-01, Volume: 58, Issue:5 Topics: Animals; Antifungal Agents; Azithromycin; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Itraconazole; Male; Mice; Mice, Inbred BALB C; Paracoccidioides; Paracoccidioidomycosis; Pentoxifylline; Pulmonary Fibrosis; Random Allocation; Thalidomide; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2020
The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study. PLoS neglected tropical diseases, 2021, Volume: 15, Issue:7 Topics: Adrenal Cortex Hormones; BCG Vaccine; Brazil; Clofazimine; Cohort Studies; COVID-19; COVID-19 Drug Treatment; COVID-19 Testing; Dapsone; Humans; Leprosy; Pentoxifylline; Prospective Studies; Risk Factors; SARS-CoV-2; Survival Analysis; Thalidomide	2021