Page last updated: 2024-08-16

thalidomide and paclitaxel

thalidomide has been researched along with paclitaxel in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.56)18.2507
2000's23 (63.89)29.6817
2010's10 (27.78)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, Y; Guan, Y; Huo, A; Li, X; Zeng, G; Zhang, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Guinan, P; Mirochnik, Y; Ray, V; Rubenstein, M; Shaw, M; Slobodskoy, L1
Yarchoan, R1
Hong, SD; Hong, SP; Kim, MJ; Kim, YY; Myoung, H1
Levine, AM; Tulpule, A1
Chalas, E; Hindenburg, A; Jeyakumar, A1
Arlen, P; Dahut, WL; Fedenko, K; Fernandez, P; Figg, WD; Gulley, J; Hamilton, M; Kruger, EA; Noone, M; Parker, C; Pluda, J1
Aglione, S; Bajetta, E; Bernard-Marty, C; Buzzoni, R; Del Vecchio, M; Khayat, D; Nova, P; Rixe, O; Taillibert, S; Vitali, M1
Remlinger, KA1
Chaudhry, M; Chaudhry, V; Crawford, TO; Griffin, JW; Simmons-O'Brien, E1
Arlen, P; Dahut, WL; Figg, WD; Gulley, J; Horne, MK; Lakhani, N; Parker, C; Parnes, H1
Arné-Bès, MC1
Haruta, S; Inagaki, K; Kanayama, N; Kawaguchi, R; Kitanaka, T; Kobayashi, H; Kondo, T; Kurita, N; Sakamoto, Y; Terao, T; Yagyu, T; Yamada, Y1
Liu, ZS; Sun, Q; Zhang, ZL1
Peltier, AC; Russell, JW1
Oka, S; Onda, J1
Amato, RJ; Sarao, H1
Bekele, BN; Chen, I; Daliani, DD; Dieringer, PY; Logothetis, CJ; Mathew, P; Pagliaro, LC; Zhou, X1
Isner, JM; Kirchmair, R; Kusano, K; Losordo, DW; Panagiotou, E; Ropper, AH; Schratzberger, P; Silver, M; Tietz, AB; Walter, DH; Weber, A; Weinberg, DH; Yoon, YS1
Koike, H; Oki, Y; Sobue, G1
Bokar, JA; Brell, JM; Cooney, MM; Dowlati, A; Gibbons, J; Krishnamurthi, S; Ness, A; Nock, C; Remick, SC; Sanborn, SL1
Cata, JP; Dougherty, PM; Weng, HR1
Chen, JR; Tzen, CY; Yang, YC1
García-Sanz, R; González-López, TJ; Graciani, IF; Hermida, G; San Miguel, JF; Vázquez, L1
Bekele, NB; Carter, CM; Mathew, P; Pagliaro, L; Tannir, N; Tu, SM1
Aggarwal, BB; Chaturvedi, MM; Park, B; Sung, B; Yadav, VR1
Belinsky, SA; Dahlberg, SE; Fitzgerald, TJ; Hoang, T; Johnson, DH; Mehta, MP; Schiller, JH1
Bhasin, D; Chettiar, SN; Etter, JP; Hu, Z; Li, PK; Pandit, B; Xiao, Z; Zink, J1
Guo, YX; Li, Z; Liu, FF; Liu, P; Wang, XL; Zhang, HL; Zhao, S1
Andreucci, E; Barbato, G; Biagioni, A; Cianchi, F; Coratti, F; Giovannelli, L; Magnelli, L; Papucci, L; Peri, S; Schiavone, N; Staderini, F; Versienti, G1

Reviews

10 review(s) available for thalidomide and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Therapy for Kaposi's sarcoma: recent advances and experimental approaches.
    Journal of acquired immune deficiency syndromes (1999), 1999, Aug-01, Volume: 21 Suppl 1

    Topics: Administration, Oral; Alitretinoin; Anthracyclines; Antineoplastic Agents; Cyclohexanes; Humans; Immunosuppressive Agents; Liposomes; Neoplasms; O-(Chloroacetylcarbamoyl)fumagillol; Paclitaxel; Sarcoma, Kaposi; Sesquiterpenes; Thalidomide; Tretinoin

1999
Clinical aspects and management of AIDS-related Kaposi's sarcoma.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:10

    Topics: Angiogenesis Inhibitors; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Dipeptides; Humans; Infusions, Intravenous; Paclitaxel; Retinoids; Sarcoma, Kaposi; Thalidomide

2001
Metastatic melanoma: chemotherapy.
    Seminars in oncology, 2002, Volume: 29, Issue:5

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Carboplatin; Cisplatin; Clinical Trials as Topic; Cytokines; Dacarbazine; Genetic Therapy; Humans; Immunotherapy; Interferon-alpha; Interleukin-2; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Paclitaxel; Tamoxifen; Taxoids; Thalidomide

2002
Cutaneous reactions to chemotherapy drugs: the art of consultation.
    Archives of dermatology, 2003, Volume: 139, Issue:1

    Topics: Animals; Antineoplastic Agents; Bleomycin; Docetaxel; Doxorubicin; Drug Eruptions; Humans; Hydroxyurea; Paclitaxel; Skin; Taxoids; Thalidomide

2003
[Neurotoxic effects of medications: an update].
    Revue medicale de Liege, 2004, Volume: 59 Suppl 1

    Topics: Anti-Retroviral Agents; Antineoplastic Agents; Carboplatin; Cisplatin; Colchicine; Docetaxel; Humans; Interferon-alpha; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System Diseases; Taxoids; Thalidomide

2004
Advances in understanding drug-induced neuropathies.
    Drug safety, 2006, Volume: 29, Issue:1

    Topics: Antineoplastic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System Diseases; Reverse Transcriptase Inhibitors; Thalidomide

2006
[Treatment of KSHV infection].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 3

    Topics: Acquired Immunodeficiency Syndrome; Angiogenesis Inhibitors; Anthracyclines; Antineoplastic Agents; Antiretroviral Therapy, Highly Active; Herpesvirus 8, Human; Humans; Interferon alpha-2; Interferon-alpha; Paclitaxel; Radiotherapy; Recombinant Proteins; Sarcoma, Kaposi; Thalidomide; Vinblastine

2006
[Adverse effects of therapeutic drugs on peripheral nervous system].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2007, Aug-10, Volume: 96, Issue:8

    Topics: Anti-HIV Agents; Anticonvulsants; Antineoplastic Agents; Antitubercular Agents; Cisplatin; Dose-Response Relationship, Drug; Early Diagnosis; Humans; Immunosuppressive Agents; Paclitaxel; Peripheral Nervous System Diseases; Phenytoin; Tacrolimus; Thalidomide; Vincristine

2007
Drug profiles.
    The American journal of managed care, 2012, Volume: 18, Issue:1 Spec No.

    Topics: Albumin-Bound Paclitaxel; Albumins; Antibodies, Monoclonal; Drug Approval; Drug Costs; Humans; Ipilimumab; Lenalidomide; Medical Oncology; Neoplasms; Paclitaxel; Thalidomide

2012

Trials

6 trial(s) available for thalidomide and paclitaxel

ArticleYear
A randomized phase II trial of docetaxel (taxotere) plus thalidomide in androgen-independent prostate cancer.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 15

    Topics: Adenocarcinoma; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Docetaxel; Humans; Male; Middle Aged; Paclitaxel; Prostatic Neoplasms; Taxoids; Thalidomide

2001
A phase I study of paclitaxel/doxorubicin/ thalidomide in patients with androgen- independent prostate cancer.
    Clinical genitourinary cancer, 2006, Volume: 4, Issue:4

    Topics: Aged; Androgens; Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Doxorubicin; Humans; Immunologic Factors; Male; Middle Aged; Paclitaxel; Prostate-Specific Antigen; Prostatic Neoplasms; Thalidomide; Treatment Outcome

2006
Thalidomide/estramustine/paclitaxel in metastatic androgen-independent prostate cancer.
    Clinical genitourinary cancer, 2006, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Disease Progression; Estramustine; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Paclitaxel; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Rate; Taxoids; Thalidomide; Time Factors; Treatment Outcome

2006
Phase I trial of docetaxel and thalidomide: a regimen based on metronomic therapeutic principles.
    Investigational new drugs, 2008, Volume: 26, Issue:4

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Neovascularization, Pathologic; Paclitaxel; Thalidomide

2008
A modular Phase I study of lenalidomide and paclitaxel in metastatic castration-resistant prostate cancer following prior taxane therapy.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:4

    Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bridged-Ring Compounds; Combined Modality Therapy; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Lenalidomide; Male; Middle Aged; Nausea; Neutropenia; Orchiectomy; Paclitaxel; Prostate-Specific Antigen; Prostatic Neoplasms; Survival Analysis; Taxoids; Thalidomide; Treatment Outcome; Vomiting

2010
Randomized phase III study of thoracic radiation in combination with paclitaxel and carboplatin with or without thalidomide in patients with stage III non-small-cell lung cancer: the ECOG 3598 study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Feb-20, Volume: 30, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Disease-Free Survival; Drug Administration Schedule; Fatigue; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Micrometastasis; Neoplasm Staging; Paclitaxel; Survival Rate; Thalidomide; Thromboembolism

2012

Other Studies

20 other study(ies) available for thalidomide and paclitaxel

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Stable and orally bio-available pro-drugs of CPS11.
    Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21

    Topics: Biological Availability; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Drug Stability; Endothelium, Vascular; Female; Humans; Prodrugs; Thalidomide; Umbilical Veins; Xenograft Model Antitumor Assays

2011
Paclitaxel is more effective than thalidomide in inhibiting LNCaP tumor growth in a prostate cancer model.
    Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:9

    Topics: Androgen Antagonists; Animals; Antineoplastic Agents, Phytogenic; Humans; Male; Mice; Mice, Nude; Paclitaxel; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Thalidomide; Tumor Cells, Cultured

1998
Evaluation of the anti-tumor and anti-angiogenic effect of paclitaxel and thalidomide on the xenotransplanted oral squamous cell carcinoma.
    Cancer letters, 2001, Feb-26, Volume: 163, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Endothelial Growth Factors; Female; Humans; Lymphokines; Mice; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; RNA, Messenger; Thalidomide; Transplantation, Heterologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Sustained complete remission in a patient with platinum-resistant ovarian yolk sac tumor.
    Gynecologic oncology, 2001, Volume: 82, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Docetaxel; Drug Resistance, Neoplasm; Endodermal Sinus Tumor; Female; Gemcitabine; Humans; Ovarian Neoplasms; Paclitaxel; Taxoids; Thalidomide

2001
Toxic neuropathy in patients with pre-existing neuropathy.
    Neurology, 2003, Jan-28, Volume: 60, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Male; Middle Aged; Neural Conduction; Oropharyngeal Neoplasms; Paclitaxel; Peripheral Nervous System Diseases; Severity of Illness Index; Thalidomide; Vincristine

2003
Increased frequency of venous thromboembolism with the combination of docetaxel and thalidomide in patients with metastatic androgen-independent prostate cancer.
    Pharmacotherapy, 2003, Volume: 23, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Middle Aged; Paclitaxel; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Retrospective Studies; Taxoids; Thalidomide; Venous Thrombosis

2003
Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappaB activation and subsequently suppressed ovarian cancer dissemination.
    Cancer research, 2005, Nov-15, Volume: 65, Issue:22

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chondrosarcoma; Drug Synergism; Female; Gene Expression; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Ovarian Neoplasms; Paclitaxel; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Thalidomide; Transforming Growth Factor beta; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator; Xenograft Model Antitumor Assays

2005
[Anti-tumor effect of thalidomide and paclitaxel on hepatocellular carcinoma in nude mice].
    Chinese medical journal, 2005, Oct-20, Volume: 118, Issue:20

    Topics: Animals; Antigens, CD34; Cell Line, Tumor; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Thalidomide; Transplantation, Heterologous

2005
Therapeutic angiogenesis inhibits or rescues chemotherapy-induced peripheral neuropathy: taxol- and thalidomide-induced injury of vasa nervorum is ameliorated by VEGF.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2007, Volume: 15, Issue:1

    Topics: Animals; Apoptosis; Cells, Cultured; Drug Therapy, Combination; Electrophysiology; Endothelial Cells; Humans; Injections, Intramuscular; Lectins; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neovascularization, Pathologic; Paclitaxel; Peripheral Nervous System Diseases; Phosphatidylinositol 3-Kinases; Plasmids; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Renal Circulation; Thalidomide; Vasa Nervorum; Vascular Endothelial Growth Factor A

2007
The effects of thalidomide and minocycline on taxol-induced hyperalgesia in rats.
    Brain research, 2008, Sep-10, Volume: 1229

    Topics: Animals; Anti-Bacterial Agents; Behavior, Animal; Hyperalgesia; Immunosuppressive Agents; Locomotion; Male; Minocycline; Paclitaxel; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Rotarod Performance Test; Statistics, Nonparametric; Thalidomide

2008
Metronomic paclitaxel and thalidomide for rapidly metastatic primary vulvar malignant rhabdoid tumor.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2009, Volume: 106, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Paclitaxel; Pleural Neoplasms; Rhabdoid Tumor; Thalidomide; Vulvar Neoplasms; Young Adult

2009
The combination of thalidomide, cyclophosphamide and dexamethasone is potentially useful in highly resistant Hodgkin's lymphoma.
    European journal of haematology, 2010, Volume: 84, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Dexamethasone; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Hodgkin Disease; Humans; Male; Mechlorethamine; Melphalan; Organoplatinum Compounds; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Prednisolone; Prednisone; Procarbazine; Remission Induction; Rituximab; Salvage Therapy; Thalidomide; Topotecan; Transplantation, Autologous; Vidarabine; Vinblastine; Vincristine

2010
Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway.
    Biochemical pharmacology, 2011, Nov-01, Volume: 82, Issue:9

    Topics: Antineoplastic Agents; Cell Line; Cell Proliferation; Diterpenes; Enzyme Inhibitors; Epoxy Compounds; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Inflammation; Leukemia; Molecular Structure; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Paclitaxel; Phenanthrenes; Signal Transduction; Thalidomide; Tumor Necrosis Factor-alpha

2011
Structure-activity relationship studies of thalidomide analogs with a taxol-like mode of action.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: Cell Line, Tumor; Cell Proliferation; Humans; Isoindoles; Microtubules; Paclitaxel; Structure-Activity Relationship; Thalidomide; Tubulin Modulators

2013
Proinflammatory Factors Mediate Paclitaxel-Induced Impairment of Learning and Memory.
    Mediators of inflammation, 2018, Volume: 2018

    Topics: Animals; Hippocampus; Interleukin-1beta; Learning; Male; Maze Learning; Memory; Paclitaxel; Rats; Rats, Sprague-Dawley; Thalidomide; Tumor Necrosis Factor-alpha

2018
Enhanced Vasculogenic Capacity Induced by 5-Fluorouracil Chemoresistance in a Gastric Cancer Cell Line.
    International journal of molecular sciences, 2021, Jul-19, Volume: 22, Issue:14

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Endothelial Cells; Fluorouracil; Humans; Neovascularization, Pathologic; Paclitaxel; Stomach Neoplasms; Thalidomide; Thymidine Phosphorylase; Up-Regulation

2021