Page last updated: 2024-08-16

thalidomide and hydroxyurea

thalidomide has been researched along with hydroxyurea in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.50)18.7374
1990's1 (3.13)18.2507
2000's8 (25.00)29.6817
2010's11 (34.38)24.3611
2020's8 (25.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Jusko, WJ1
Buu-Hoï, NP; Lambelin, G; Roba, J1
Soukup, S; Takacs, E; Warkany, J1
Bertoli, D; Borelli, G1
Lisziewicz, J; Lori, F; Ravot, E1
Cervantes, F2
Remlinger, KA1
Brito-Babapulle, F; Fielden, J; Rechner, I1
Byars, T; Cox, CE; Hartung, C; Judson, MA; Silvestri, J1
Brady, H; Chan, K; Corral, LG; Ferguson, GD; Glezer, E; Jensen-Pergakes, K; Morris, CL; Moutouh-de Parseval, LA; Muller, G; Verhelle, D1
Chmarzyńska, E; Dwilewicz-Trojaczek, J; Jędrzejczak, WW; Koperski, Ł; Pastwińska, A; Paszkowska-Kowalewska, M; Ziarkiewicz, M; Ziarkiewicz-Wróblewska, B1
Corral, LG; Kutlar, A; Kutlar, F; Meiler, SE; Moutouh-de Parseval, LA; Swerdlow, PS; Wade, M; Xue, Y; Yerigenahally, SD1
Breda, L; Gambari, R; Rivella, S; Zuccato, C1
Miyamoto, T; Yoshimoto, G1
Foley, P; Kelly, JB; Strober, BE1
Aylı, M; Cengiz Seval, G; Özcan, M1
Ammirabile, M; Cinque, P; Costantini, S; De Dominicis, G; Di Matola, T; Filosa, A; Marsella, M; Ricchi, P; Spasiano, A1
Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E1
Chin, CM; Costa, FF; de Melo, TR; Dos Santos, JL; Fertrin, KY; Franco-Penteado, CF; Kutlar, A; Lanaro, C; Meiler, SE; Silva, FH; Wade, M; Yerigenahally, S1
Patel, K; Shah, K; Shah, S; Sheth, R1
Abdulmalik, O; Blobel, GA; Giardine, BM; Hardison, RC; Huang, P; Keller, CA; Khandros, E; Peslak, SA; Sharma, M; Zhang, Z1
Baul, SN; Chakrabarti, P; De, R; Dolai, TK; Ghosh, P; Jain, M; Mandal, PK1
Agrawal, N; Ahmed, R; Arora, JS; Bhurani, D; Kapoor, J; Khushoo, V; Mehta, P; Yadav, N1
Borg, J; Borg, K; Grech, L; Sultana, J1
Adil, SO; Ansari, AH; Ansari, I; Ansari, SH; Ansari, UH; Farooq, F; Hussain, Z; Khawaja, S; Masqati, NU; Sattar, A; Wasim, M; Zohaib, M1
Ali, M; Ali, Z; Ismail, M; Khan, MTM; Rani, GF; Rehman, IU1

Reviews

8 review(s) available for thalidomide and hydroxyurea

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New uses for old drugs in HIV infection: the role of hydroxyurea, cyclosporin and thalidomide.
    Drugs, 1999, Volume: 58, Issue:6

    Topics: Cyclosporine; HIV Infections; Humans; Hydroxyurea; Immunosuppressive Agents; Nucleic Acid Synthesis Inhibitors; Thalidomide

1999
Prognostic factors and current practice in treatment of myelofibrosis with myeloid metaplasia: an update anno 2000.
    Pathologie-biologie, 2001, Volume: 49, Issue:2

    Topics: Aged; Anemia; Aneuploidy; Angiogenesis Inhibitors; Bone Marrow Transplantation; Case Management; Combined Modality Therapy; Female; Hemoglobins; Humans; Hydroxyurea; Karyotyping; Male; Middle Aged; Palliative Care; Primary Myelofibrosis; Prognosis; Quinazolines; Risk; Severity of Illness Index; Splenectomy; Survival Analysis; Thalidomide

2001
Cutaneous reactions to chemotherapy drugs: the art of consultation.
    Archives of dermatology, 2003, Volume: 139, Issue:1

    Topics: Animals; Antineoplastic Agents; Bleomycin; Docetaxel; Doxorubicin; Drug Eruptions; Humans; Hydroxyurea; Paclitaxel; Skin; Taxoids; Thalidomide

2003
Myelofibrosis: biology and treatment options.
    European journal of haematology. Supplementum, 2007, Issue:68

    Topics: Benzamides; Chronic Disease; Darbepoetin alfa; Erythropoietin; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Piperazines; Primary Myelofibrosis; Protein-Tyrosine Kinases; Pyrimidines; Quinazolines; Recombinant Proteins; Splenectomy; Thalidomide

2007
[Treatment strategy for myeloproliferative neoplasms].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Adrenal Cortex Hormones; Aspirin; Calreticulin; Carbamates; Clinical Trials as Topic; Drug Therapy, Combination; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Immunosuppressive Agents; Janus Kinase 2; Molecular Targeted Therapy; Mutation; Nitriles; Platelet Aggregation Inhibitors; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Pyrazoles; Pyrimidines; Quinazolines; Receptors, Thrombopoietin; Thalidomide; Thrombocythemia, Essential

2014
Current and future oral systemic therapies for psoriasis.
    Dermatologic clinics, 2015, Volume: 33, Issue:1

    Topics: Acitretin; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Cyclosporine; Fumarates; Humans; Hydroxyurea; Immunosuppressive Agents; Isoxazoles; Keratolytic Agents; Leflunomide; Methotrexate; Mycophenolic Acid; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrimidines; Pyrroles; Sulfasalazine; Thalidomide; Thioguanine

2015
Drug safety in thalassemia: lessons from the present and directions for the future.
    Expert opinion on drug safety, 2021, Volume: 20, Issue:8

    Topics: Activin Receptors, Type II; beta-Thalassemia; Hematinics; Humans; Hydroxyurea; Immunoglobulin Fc Fragments; Iron Chelating Agents; Recombinant Fusion Proteins; Thalidomide

2021

Trials

3 trial(s) available for thalidomide and hydroxyurea

ArticleYear
The effect of thalidomide on corticosteroid-dependent pulmonary sarcoidosis.
    Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2006, Volume: 23, Issue:1

    Topics: Adrenal Cortex Hormones; Black or African American; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Methotrexate; Middle Aged; Pilot Projects; Prednisone; Prospective Studies; Quality of Life; Sarcoidosis, Pulmonary; Surveys and Questionnaires; Thalidomide; Time Factors; Treatment Outcome; White People

2006
Safety and effectiveness of thalidomide and hydroxyurea combination in β-thalassaemia intermedia and major: a retrospective pilot study.
    British journal of haematology, 2020, Volume: 188, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Child; Child, Preschool; Female; Humans; Hydroxyurea; Male; Retrospective Studies; Thalidomide

2020
Long-term clinical efficacy and safety of thalidomide in patients with transfusion-dependent β-thalassemia: results from Thal-Thalido study.
    Scientific reports, 2023, 08-21, Volume: 13, Issue:1

    Topics: beta-Thalassemia; Ferritins; Humans; Hydroxyurea; Thalidomide; Treatment Outcome; Uric Acid

2023

Other Studies

21 other study(ies) available for thalidomide and hydroxyurea

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Pharmacodynamic principles in chemical teratology: dose-effect relationships.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:3

    Topics: Abnormalities, Drug-Induced; Adsorption; Cyclophosphamide; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Female; Fluorouracil; Gestational Age; Humans; Hydroxyurea; Kinetics; Lethal Dose 50; Maternal-Fetal Exchange; Models, Biological; Pharmaceutical Preparations; Pregnancy; Receptors, Drug; Thalidomide; Time Factors

1972
Teratological studies of p-butoxyphenylacethydroxamic acid (CP 1044 J3) in rats and rabbits.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Fetal Death; Hydroxamic Acids; Hydroxyurea; Lactose; Male; Phenylacetates; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Thalidomide

1970
Chromosome changes in embryos treated with various teratogens.
    Journal of embryology and experimental morphology, 1967, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Chromosome Aberrations; Diet; Female; Hydroxyurea; Mechlorethamine; Mitosis; Nitrogen Mustard Compounds; Pregnancy; Rabbits; Rats; Streptonigrin; Thalidomide

1967
[Teratogenic action of Rifaximin in the rat and rabbit and its effect on perinatal development in the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1984, May-30, Volume: 60, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Hydroxyurea; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Rats, Inbred Strains; Rifamycins; Rifaximin; Thalidomide

1984
Systemic capillary leak syndrome after granulocyte colony-stimulating factor (G-CSF).
    The hematology journal : the official journal of the European Haematology Association, 2003, Volume: 4, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capillary Leak Syndrome; Combined Modality Therapy; Critical Care; Cyclophosphamide; Dexamethasone; Doxorubicin; Dyspnea; Edema; Fasciitis, Necrotizing; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methylprednisolone; Middle Aged; Models, Biological; Multiple Myeloma; Peripheral Blood Stem Cell Transplantation; Thalidomide; Vasculitis, Leukocytoclastic, Cutaneous; Vincristine

2003
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells.
    The Journal of clinical investigation, 2008, Volume: 118, Issue:1

    Topics: Anemia, Sickle Cell; Antigens, CD34; Antineoplastic Agents; Antisickling Agents; beta-Thalassemia; Blood Transfusion; Cells, Cultured; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Synergism; Erythroid Cells; Erythropoiesis; Fetal Hemoglobin; Humans; Hydroxyurea; Lenalidomide; Models, Biological; Thalidomide; Up-Regulation

2008
Refractory anaemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T) with superimposed 5q-syndrome.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2010, Volume: 61, Issue:2

    Topics: Aged; Anemia, Macrocytic; Anemia, Refractory; Anemia, Sideroblastic; Antineoplastic Agents; Bone Marrow Cells; Chromosome Deletion; Chromosomes, Human, Pair 5; Drug Therapy, Combination; Humans; Hydroxyurea; In Situ Hybridization, Fluorescence; Lenalidomide; Male; Thalidomide; Thrombocytosis

2010
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.
    Blood, 2011, Jul-28, Volume: 118, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Bone Marrow; Disease Models, Animal; Erythropoiesis; Fetal Hemoglobin; Hydroxyurea; Mice; Mice, Knockout; Mice, Transgenic; Thalidomide

2011
Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia.
    Expert review of hematology, 2013, Volume: 6, Issue:3

    Topics: Antisickling Agents; Azacitidine; beta-Globins; beta-Thalassemia; Decitabine; Fetal Hemoglobin; Genetic Therapy; Genetic Vectors; Humans; Hydroxyurea; Lentivirus; Retroviridae; Thalidomide

2013
Ruxolitinib Treatment in a Patient with Primary Myelofibrosis Resistant to Conventional Therapies and Splenectomy: A Case Report.
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2015, Volume: 32, Issue:2

    Topics: Aged; Aspergillosis; Blood Transfusion; Danazol; Disease Progression; Drug Resistance; Fatal Outcome; Humans; Hydroxyurea; Janus Kinase 2; Lenalidomide; Leukemia, Myeloid, Acute; Male; Nitriles; Primary Myelofibrosis; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Splenectomy; Splenic Infarction; Thalidomide

2015
The long-term and extensive efficacy of low dose thalidomide in a case of an untransfusable patient with Non-Transfusion-Dependent Thalassemia.
    Blood cells, molecules & diseases, 2016, Volume: 57

    Topics: Antisickling Agents; Blood Transfusion; Bone Marrow; Drug Administration Schedule; Female; Fetal Hemoglobin; Hemoglobin A2; Humans; Hydroxyurea; Immunosuppressive Agents; Isoantibodies; Middle Aged; Splenectomy; Thalassemia; Thalidomide; Treatment Outcome

2016
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
A thalidomide-hydroxyurea hybrid increases HbF production in sickle cell mice and reduces the release of proinflammatory cytokines in cultured monocytes.
    Experimental hematology, 2018, Volume: 58

    Topics: Anemia, Sickle Cell; Animals; Cytokines; Disease Models, Animal; Fetal Hemoglobin; Hydroxyurea; Inflammation; Mice; Mice, Knockout; Thalidomide

2018
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.
    Blood, 2020, 05-28, Volume: 135, Issue:22

    Topics: Adult; Anemia, Sickle Cell; Cell Line; Cell Separation; Cells, Cultured; Erythroblasts; Erythroid Cells; Fetal Hemoglobin; Gene Expression Profiling; Hemoglobin A; Humans; Hydroxyurea; Proteomics; RNA, Messenger; Thalidomide

2020
Comparison of efficacy and safety of thalidomide vs hydroxyurea in patients with Hb E-β thalassemia - a pilot study from a tertiary care Centre of India.
    Blood cells, molecules & diseases, 2021, Volume: 88

    Topics: Adolescent; Adult; Antisickling Agents; beta-Thalassemia; Child; Female; Hemoglobin E; Hemoglobins; Humans; Hydroxyurea; Immunosuppressive Agents; India; Male; Pilot Projects; Prospective Studies; Tertiary Care Centers; Thalidomide; Young Adult

2021
Experience with combination of hydroxyurea and low-dose thalidomide in transfusion-dependent beta thalassemia patients.
    Annals of hematology, 2021, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Antisickling Agents; beta-Thalassemia; Blood Transfusion; Child; Drug Combinations; Female; Ferritins; Follow-Up Studies; Humans; Hydroxyurea; Immunosuppressive Agents; Male; Retrospective Studies; Thalidomide; Young Adult

2021
Evaluation of the combination therapy of hydroxyurea and thalidomide in β-thalassemia.
    Blood advances, 2022, 12-27, Volume: 6, Issue:24

    Topics: beta-Thalassemia; Blood Transfusion; Child; Combined Modality Therapy; Female; Humans; Hydroxyurea; Male; Thalidomide; Transfusion Reaction

2022