Page last updated: 2024-08-16

thalidomide and glutarimide

thalidomide has been researched along with glutarimide in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Bär, K; Boichenko, I; Deiss, S; Hartmann, MD; Hernandez Alvarez, B1
Bär, K; Giannis, A; Hartmann, MD; Heim, C; Hernandez Alvarez, B; Mousavizadeh, F; Pliatsika, D1
Shull, GE1
SOMERS, GF1
PARKASH, O1
BERITIC, T; MARKICEVIC, A1
FRATTA, I; SIGG, EB; WUEST, HM1
Meng, Y; Tian, C; Wang, Z; Xiu, P; Zhao, W; Zhou, R1
Adamchik, M; Bubyrev, A; Bunev, A; Hartmann, MD; Heim, C; Krasavin, M; Maiwald, S; Zhmurov, P; Zhukovsky, D1

Other Studies

9 other study(ies) available for thalidomide and glutarimide

ArticleYear
A FRET-Based Assay for the Identification and Characterization of Cereblon Ligands.
    Journal of medicinal chemistry, 2016, Jan-28, Volume: 59, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Caenorhabditis elegans Proteins; Drug Design; Fluorescence Resonance Energy Transfer; High-Throughput Screening Assays; Humans; Ligands; Magnetospirillum; Models, Molecular; Peptide Hydrolases; Protein Binding; Small Molecule Libraries; Teratogens; Ubiquitin-Protein Ligases

2016
De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
    Journal of medicinal chemistry, 2019, 07-25, Volume: 62, Issue:14

    Topics: Adaptor Proteins, Signal Transducing; Cell Line; Drug Design; Humans; Hydrolysis; Ikaros Transcription Factor; Molecular Docking Simulation; Proteolysis; Thalidomide; Ubiquitin-Protein Ligases

2019
Differential inhibition of protein synthesis: a possible biochemical mechanism of thalidomide teratogenesis.
    Journal of theoretical biology, 1984, Oct-05, Volume: 110, Issue:3

    Topics: Abnormalities, Drug-Induced; Acylation; Animals; Chemical Phenomena; Chemistry; Cycloheximide; Embryonic and Fetal Development; Gene Expression Regulation; Humans; Imides; Models, Biological; Piperidones; Polyamines; Protein Biosynthesis; Pyrimidines; Rabbits; RNA, Messenger; Teratogens; Thalidomide

1984
Pharmacological properties of thalidomide (alpha-phthalimido glutarimide), a new sedative hypnotic drug.
    British journal of pharmacology and chemotherapy, 1960, Volume: 15

    Topics: Animals; Barbiturates; Central Nervous System Depressants; Glutamates; Hypnotics and Sedatives; Mice; Piperidones; Sleep; Thalidomide; Tranquilizing Agents

1960
[Abnormalities caused by Contergan (thalidomide, N-phtalimido-glutarimide) in Drosophila melanogaster].
    Wiener klinische Wochenschrift, 1962, Dec-21, Volume: 74

    Topics: Animals; Congenital Abnormalities; Drosophila; Drosophila melanogaster; Piperidones; Thalidomide

1962
[Teratogenic effects of glutarimide derivatives].
    Lijecnicki vjesnik, 1962, Volume: 84

    Topics: Ectromelia; Piperidones; Thalidomide

1962
PHARMACOLOGICAL PROPERTIES AND TERATOGENIC ACTION OF 2-(HEXAHYDROPHTHALIMIDO) GLUTARIMIDE AND 2-PHTHALIMIDO-N-METHYLGLUTARIMIDE.
    Life sciences (1962), 1964, Volume: 3

    Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Mice; Piperidines; Piperidones; Pregnancy; Pregnancy, Animal; Rabbits; Research; Thalidomide; Toxicology

1964
Enantiomerization mechanism of thalidomide and the role of water and hydroxide ions.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Nov-05, Volume: 18, Issue:45

    Topics: Catalysis; Hydroxides; Molecular Conformation; Piperidones; Quantum Theory; Stereoisomerism; Thalidomide; Thermodynamics; Water

2012
Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines.
    European journal of medicinal chemistry, 2023, Jan-15, Volume: 246

    Topics: Adaptor Proteins, Signal Transducing; Cell Line, Tumor; Humans; Multiple Myeloma; Peptide Hydrolases; Proteolysis; Thalidomide; Ubiquitin-Protein Ligases

2023