Page last updated: 2024-08-16

thalidomide and cps 49

thalidomide has been researched along with cps 49 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eger, K; Figg, WD; Gütschow, M; MacPherson, GR; Ng, SS1
Anderson, KC; Figg, WD; Hamasaki, M; Hideshima, T; Ishitsuka, K; Kumar, S; Munshi, NC; Raje, N; Richardson, P; Roccaro, A; Shiraishi, N; Yasui, H1
Dennis, PA; Figg, WD; Lepper, ER; Warfel, NA; Zhang, C1
Byun, JS; De Luca, P; De Siervi, A; Figg, WD; Gardner, K; Ge, Y; Gueron, G; Haggerty, CM; Li, QQ; Quintero, J; Sadiq-Ali, SG; Yabe, IM1
Erskine, L; Figg, WD; Gardner, ER; Therapontos, C; Vargesson, N1
Cotignola, J; De Luca, P; De Siervi, A; Elguero, B; Figg, WD; Gardner, K; Meiss, R; Spallanzani, RG; Vallecorsa, P; Vazquez, E; Zalazar, F1
Beedie, SL; Erskine, L; Figg, WD; Fraga, LR; Gütschow, M; Mahony, C; McMenemy, S; Rafipay, AJ; Vargesson, N1

Other Studies

7 other study(ies) available for thalidomide and cps 49

ArticleYear
Antitumor effects of thalidomide analogs in human prostate cancer xenografts implanted in immunodeficient mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Male; Mice; Mice, SCID; Microcirculation; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Platelet Endothelial Cell Adhesion Molecule-1; Platelet-Derived Growth Factor; Prostatic Neoplasms; Protein Isoforms; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thalidomide; Time Factors

2004
Antimyeloma activity of two novel N-substituted and tetraflourinated thalidomide analogs.
    Leukemia, 2005, Volume: 19, Issue:7

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Multiple Myeloma; Stromal Cells; Thalidomide

2005
Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-01, Volume: 12, Issue:11 Pt 1

    Topics: Animals; Butadienes; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Mice; Mice, SCID; Mitogen-Activated Protein Kinase 14; Neoplasms; Nitriles; Pyridines; Structure-Activity Relationship; Thalidomide; Xenograft Model Antitumor Assays

2006
Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol.
    Molecular pharmacology, 2008, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Cell Death; Cell Line, Tumor; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Free Radical Scavengers; Glutathione; Homeostasis; Humans; Intracellular Space; Leukemia; Membrane Potential, Mitochondrial; Mitochondria; NF-kappa B; Nuclear Proteins; Organ Specificity; Oxidation-Reduction; Piperidines; Proto-Oncogene Proteins; Reactive Oxygen Species; Thalidomide; Transcription, Genetic; Tumor Suppressor Proteins

2008
Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, May-26, Volume: 106, Issue:21

    Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chick Embryo; Cytoskeleton; Humans; Inflammation Mediators; Limb Deformities, Congenital; Neovascularization, Physiologic; Pseudopodia; Signal Transduction; Thalidomide; Time Factors

2009
Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer.
    Current pharmaceutical biotechnology, 2015, Volume: 16, Issue:6

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Combinations; Flavonoids; Humans; Male; Mice; Mice, Nude; Piperidines; Prostatic Neoplasms; Thalidomide; Treatment Outcome

2015
CPS49-induced neurotoxicity does not cause limb patterning anomalies in developing chicken embryos.
    Journal of anatomy, 2018, Volume: 232, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Body Patterning; Bungarotoxins; Chick Embryo; Embryonic Development; Extremities; Female; Limb Buds; Limb Deformities, Congenital; Mice; Mice, Inbred C57BL; Neuronal Outgrowth; Neurotoxicity Syndromes; Teratogens; Thalidomide

2018