Compounds > thalidomide
Page last updated: 2024-08-16

thalidomide and 5'-hydroxythalidomide

thalidomide has been researched along with 5'-hydroxythalidomide in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Ando, Y; Figg, WD; Kruger, EA; Price, DK; Weiss, M1
Hara, H; Matsunaga, N; Nakamura, S; Shibata, N; Takashima, M; Toru, T; Yamamoto, T1
Chowdhury, G; Guengerich, FP; Igaya, S; Nakamura, M; Shibata, N; Shimizu, M; Suemizu, H; Yamazaki, H1
Hasegawa, T; Kitajima, S; Kuwagata, M; Shimizu, M; Takashima, H; Yamazaki, H1
Shimizu, M; Yamazaki, H1

Other Studies

5 other study(ies) available for thalidomide and 5'-hydroxythalidomide

ArticleYear
5'-OH-thalidomide, a metabolite of thalidomide, inhibits angiogenesis.
    Therapeutic drug monitoring, 2002, Volume: 24, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Aorta, Thoracic; Endothelium, Vascular; Humans; Male; Neovascularization, Physiologic; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Saphenous Vein; Thalidomide

2002
Enzymatic resolution and evaluation of enantiomers of cis-5'-hydroxythalidomide.
    Organic & biomolecular chemistry, 2008, May-07, Volume: 6, Issue:9

    Topics: Catalysis; Hydrogen-Ion Concentration; Kinetics; Lipase; Molecular Conformation; Pseudomonas stutzeri; Stereoisomerism; Thalidomide

2008
In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.
    Chemical research in toxicology, 2012, Feb-20, Volume: 25, Issue:2

    Topics: Animals; Chimera; Glutathione; Hepatocytes; Humans; Hydroxylation; Mice; Teratogens; Thalidomide

2012
Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5'-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species.
    The Journal of toxicological sciences, 2021, Volume: 46, Issue:12

    Topics: Administration, Oral; Animals; Liver; Male; Mice; Rabbits; Thalidomide

2021
Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:1

    Topics: Animals; Coumarins; Cytochrome P-450 Enzyme System; Female; Humans; Microsomes, Liver; Oxidation-Reduction; Pregnancy; Rabbits; Rats; Species Specificity; Thalidomide

2023