Page last updated: 2024-09-04

tezosentan and sildenafil citrate

tezosentan has been researched along with sildenafil citrate in 2 studies

Compound Research Comparison

Studies (tezosentan)	Trials (tezosentan)	Recent Studies (post-2010) (tezosentan)	Studies (sildenafil citrate)	Trials (sildenafil citrate)	Recent Studies (post-2010) (sildenafil citrate)
157	29	33	5,862	956	2,319

Protein Interaction Comparison

Protein	Taxonomy	tezosentan (IC50)	sildenafil citrate (IC50)
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)		0.0036

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adatia, I; Coates, AL; Humpl, T; Katz, SL; Leung, K; Louca, E; Reyes, JT	1
Albu, G; Beghetti, M; Fontao, F; Habre, W; Janosi, TZ; Petak, F; von Ungern-Sternberg, BS	1

Other Studies

2 other study(ies) available for tezosentan and sildenafil citrate

Article	Year
Nebulized therapies for childhood pulmonary hypertension: an in vitro model. Pediatric pulmonology, 2006, Volume: 41, Issue:7 Topics: Adolescent; Antihypertensive Agents; Child; Epoprostenol; Humans; Hypertension, Pulmonary; Models, Theoretical; Nebulizers and Vaporizers; Piperazines; Purines; Pyridines; Sildenafil Citrate; Sulfones; Tetrazoles; Vasodilator Agents	2006
Prevention of bronchial hyperreactivity in a rat model of precapillary pulmonary hypertension. Respiratory research, 2011, Apr-27, Volume: 12 Topics: Administration, Oral; Airway Resistance; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension, Pulmonary; Iloprost; Infusion Pumps, Implantable; Infusions, Parenteral; Lung; Lung Volume Measurements; Male; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Piperazines; Prostaglandins I; Purines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Sildenafil Citrate; Sulfones; Tetrazoles; Time Factors; Vasoactive Intestinal Peptide; Vasodilator Agents	2011

Article

Year

Nebulized therapies for childhood pulmonary hypertension: an in vitro model.

Pediatric pulmonology, 2006, Volume: 41, Issue:7

Topics: Adolescent; Antihypertensive Agents; Child; Epoprostenol; Humans; Hypertension, Pulmonary; Models, Theoretical; Nebulizers and Vaporizers; Piperazines; Purines; Pyridines; Sildenafil Citrate; Sulfones; Tetrazoles; Vasodilator Agents

2006

Prevention of bronchial hyperreactivity in a rat model of precapillary pulmonary hypertension.

Respiratory research, 2011, Apr-27, Volume: 12

Topics: Administration, Oral; Airway Resistance; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension, Pulmonary; Iloprost; Infusion Pumps, Implantable; Infusions, Parenteral; Lung; Lung Volume Measurements; Male; Nitric Oxide; Phosphodiesterase 5 Inhibitors; Piperazines; Prostaglandins I; Purines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Sildenafil Citrate; Sulfones; Tetrazoles; Time Factors; Vasoactive Intestinal Peptide; Vasodilator Agents

2011