Page last updated: 2024-09-04

tezosentan and natriuretic peptide, brain

tezosentan has been researched along with natriuretic peptide, brain in 10 studies

Compound Research Comparison

Studies (tezosentan)	Trials (tezosentan)	Recent Studies (post-2010) (tezosentan)	Studies (natriuretic peptide, brain)	Trials (natriuretic peptide, brain)	Recent Studies (post-2010) (natriuretic peptide, brain)
157	29	33	16,317	1,867	8,887

Protein Interaction Comparison

Protein	Taxonomy	tezosentan (IC50)	natriuretic peptide, brain (IC50)
Atrial natriuretic peptide receptor 1	Homo sapiens (human)		0.006

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (80.00)	29.6817
2010's	2 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Teerlink, JR	2
Krum, H; Liew, D	1
Graham, CA	1
Cotter, G; Dingemanse, J; Frey, A; Kaluski, E; Kaplan, S; Kobrin, I; Milo-Cotter, O; Neuhart, E; Pacher, R; Perchenet, L; Rainisio, M; Richter, C; Stangl, K; Torre-Amione, G; Vered, Z	1
Mehra, MR	1
Böttiger, BW; Motsch, J; Rauch, H	1
Cotter, G; Dittrich, H; Felker, GM; Metra, M; Milo-Cotter, O; Teerlink, JR; Voors, AA; Weatherley, B	1
Ambrosy, AP; Butler, J; Gheorghiade, M; Greene, SJ; Vaduganathan, M	1
Bourge, RC; Cleland, JGF; Cotter, G; Davison, BA; Jondeau, G; Krum, H; McMurray, JJV; Metra, M; Milo, O; O'Connor, CM; Parker, JD; Senger, S; Shoaib, A; Teerlink, JR; Torre-Amione, G; van Veldhuisen, DJ	1

Reviews

8 review(s) available for tezosentan and natriuretic peptide, brain

Article	Year
Dyspnea as an end point in clinical trials of therapies for acute decompensated heart failure. American heart journal, 2003, Volume: 145, Issue:2 Suppl Topics: Acute Disease; Drug Approval; Dyspnea; Forecasting; Heart Failure; Hospitalization; Humans; Hydrazones; Natriuretic Agents; Natriuretic Peptide, Brain; Pyridazines; Pyridines; Randomized Controlled Trials as Topic; Severity of Illness Index; Simendan; Tetrazoles; Treatment Outcome; Vasodilator Agents	2003
The development of new medical treatments for acute decompensated heart failure. Heart failure monitor, 2002, Volume: 2, Issue:4 Topics: Acute Disease; Cardiotonic Agents; Cohort Studies; Heart Failure; Hemodynamics; Humans; Hydrazones; Multicenter Studies as Topic; Natriuretic Agents; Natriuretic Peptide, Brain; Placebos; Pyridazines; Pyridines; Randomized Controlled Trials as Topic; Receptors, Endothelin; Simendan; Tetrazoles; Time Factors; Vasodilator Agents	2002
New and emerging drug therapies for the management of acute heart failure. Internal medicine journal, 2003, Volume: 33, Issue:11 Topics: Antidiuretic Hormone Receptor Antagonists; Heart Failure; Humans; Hydrazones; Natriuretic Agents; Natriuretic Peptide, Brain; Pyridazines; Pyridines; Simendan; Tetrazoles; Treatment Outcome; Vasodilator Agents; Vasopressins	2003
Pharmacological therapy of acute cardiogenic pulmonary oedema in the emergency department. Emergency medicine Australasia : EMA, 2004, Volume: 16, Issue:1 Topics: Acute Disease; Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Cardiotonic Agents; Critical Illness; Developed Countries; Diuretics; Emergency Service, Hospital; Emergency Treatment; Evidence-Based Medicine; Furosemide; Heart Failure; Humans; Hydrazones; Natriuretic Agents; Natriuretic Peptide, Brain; Nitroprusside; Oxygen Inhalation Therapy; Patient Selection; Pulmonary Edema; Pyridazines; Pyridines; Simendan; Tetrazoles; Treatment Outcome; Vasodilator Agents	2004
Optimizing outcomes in the patient with acute decompensated heart failure. American heart journal, 2006, Volume: 151, Issue:3 Topics: Biomarkers; Cardiotonic Agents; Diuretics; Heart Failure; Hemodynamics; Humans; Hydrazones; Milrinone; Natriuretic Agents; Natriuretic Peptide, Brain; Nitroglycerin; Pyridazines; Pyridines; Risk Assessment; Simendan; Tetrazoles; Therapeutics; Troponin; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure	2006
Newer approaches to the pharmacological management of heart failure. Current opinion in anaesthesiology, 2006, Volume: 19, Issue:1 Topics: Calcium Signaling; Cardiotonic Agents; Cardiovascular Agents; Endothelins; Enzyme Inhibitors; Heart Failure; Humans; Hydrazones; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridazines; Pyridines; Simendan; Tetrazoles	2006
Vasodilators in the treatment of acute heart failure: what we know, what we don't. Heart failure reviews, 2009, Volume: 14, Issue:4 Topics: Acute Disease; Atrial Natriuretic Factor; Benzoates; Elapid Venoms; Endothelin-1; Heart Failure; Humans; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Nitrates; Peptide Fragments; Prognosis; Pyridines; Receptors, Endothelin; Relaxin; Tetrazoles; Vasoconstriction; Vasodilator Agents	2009
The disconnect between phase II and phase III trials of drugs for heart failure. Nature reviews. Cardiology, 2013, Volume: 10, Issue:2 Topics: Animals; Benzazepines; Cardiovascular Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Evidence-Based Medicine; Heart Failure; Humans; Hydrazones; Natriuretic Peptide, Brain; Patient Readmission; Patient Selection; Pyridazines; Pyridines; Risk Assessment; Risk Factors; Simendan; Tetrazoles; Time Factors; Tolvaptan; Treatment Outcome; Xanthines	2013

Trials

2 trial(s) available for tezosentan and natriuretic peptide, brain

Article	Year
The hemodynamic and neurohormonal effects of low doses of tezosentan (an endothelin A/B receptor antagonist) in patients with acute heart failure. European journal of heart failure, 2004, Volume: 6, Issue:5 Topics: Aged; Double-Blind Method; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelins; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Prospective Studies; Pyridines; Tetrazoles	2004
Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (V European journal of heart failure, 2017, Volume: 19, Issue:6 Topics: Acute Disease; Aged; Biomarkers; Dose-Response Relationship, Drug; Europe; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Humans; Injections, Intravenous; Male; Middle Aged; Natriuretic Peptide, Brain; Patient Admission; Patient Discharge; Prognosis; Pyridines; Receptors, Endothelin; Retrospective Studies; Survival Rate; Tetrazoles; Time Factors; Troponin I; United States; Vasodilator Agents	2017

Article

Year

The hemodynamic and neurohormonal effects of low doses of tezosentan (an endothelin A/B receptor antagonist) in patients with acute heart failure.

European journal of heart failure, 2004, Volume: 6, Issue:5

Topics: Aged; Double-Blind Method; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelins; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Prospective Studies; Pyridines; Tetrazoles

2004

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (V

European journal of heart failure, 2017, Volume: 19, Issue:6

Topics: Acute Disease; Aged; Biomarkers; Dose-Response Relationship, Drug; Europe; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Humans; Injections, Intravenous; Male; Middle Aged; Natriuretic Peptide, Brain; Patient Admission; Patient Discharge; Prognosis; Pyridines; Receptors, Endothelin; Retrospective Studies; Survival Rate; Tetrazoles; Time Factors; Troponin I; United States; Vasodilator Agents

2017