Page last updated: 2024-09-04
tezosentan and leflunomide
tezosentan has been researched along with leflunomide in 1 studies
Compound Research Comparison
Studies (tezosentan) | Trials (tezosentan) | Recent Studies (post-2010) (tezosentan) | Studies (leflunomide) | Trials (leflunomide) | Recent Studies (post-2010) (leflunomide) |
---|---|---|---|---|---|
157 | 29 | 33 | 1,725 | 173 | 659 |
Protein Interaction Comparison
Protein | Taxonomy | tezosentan (IC50) | leflunomide (IC50) |
---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial | Mus musculus (house mouse) | 0.03 | |
Cytochrome P450 1A2 | Homo sapiens (human) | 0.5 | |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 4.63 | |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 4.63 | |
Sodium-dependent dopamine transporter | Homo sapiens (human) | 2.884 | |
Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | 5.4 | |
Dihydroorotate dehydrogenase (quinone), mitochondrial | Rattus norvegicus (Norway rat) | 0.009 |
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Other Studies
1 other study(ies) available for tezosentan and leflunomide
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |