tezosentan has been researched along with itraconazole in 2 studies
| Studies (tezosentan) | Trials (tezosentan) | Recent Studies (post-2010) (tezosentan) | Studies (itraconazole) | Trials (itraconazole) | Recent Studies (post-2010) (itraconazole) |
|---|---|---|---|---|---|
| 157 | 29 | 33 | 249 | 4 | 108 |
| Protein | Taxonomy | tezosentan (IC50) | itraconazole (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 3.89 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 0.7 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.666 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.4256 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 0.2 | |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | 2.5676 | |
| Cruzipain | Trypanosoma cruzi | 3 | |
| Vasopressin V2 receptor | Homo sapiens (human) | 3.476 | |
| C-C chemokine receptor type 4 | Homo sapiens (human) | 3.2689 | |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | 3.6 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
2 other study(ies) available for tezosentan and itraconazole
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |