Page last updated: 2024-09-04

tezosentan and dobutamine

tezosentan has been researched along with dobutamine in 2 studies

Compound Research Comparison

Studies
(tezosentan)
Trials
(tezosentan)
Recent Studies (post-2010)
(tezosentan)
Studies
(dobutamine)
Trials
(dobutamine)
Recent Studies (post-2010) (dobutamine)
15729336,3578181,011

Protein Interaction Comparison

ProteinTaxonomytezosentan (IC50)dobutamine (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)4.17
Epidermal growth factor receptorHomo sapiens (human)5.551
Tyrosine-protein kinase LckHomo sapiens (human)5.519
Tyrosine-protein kinase FynHomo sapiens (human)3.975
Beta-2 adrenergic receptorHomo sapiens (human)1.517
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.383
Beta-1 adrenergic receptorHomo sapiens (human)1.944
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.599
Alpha-2B adrenergic receptorHomo sapiens (human)2.966
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.383
Alpha-1D adrenergic receptorHomo sapiens (human)0.114
Sodium-dependent serotonin transporterHomo sapiens (human)1.895
D(3) dopamine receptorHomo sapiens (human)4.985
Sodium-dependent dopamine transporter Homo sapiens (human)0.155
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.518

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Durand, JB; Kobrin, I; Nagueh, S; Pratt, C; Torre-Amione, G; Vooletich, MT1

Trials

1 trial(s) available for tezosentan and dobutamine

ArticleYear
A pilot safety trial of prolonged (48 h) infusion of the dual endothelin-receptor antagonist tezosentan in patients with advanced heart failure.
    Chest, 2001, Volume: 120, Issue:2

    Topics: Acute Disease; Aged; Dobutamine; Double-Blind Method; Drug Tolerance; Echocardiography, Doppler; Endothelin Receptor Antagonists; Female; Heart Failure; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Pyridines; Safety; Tetrazoles

2001

Other Studies

1 other study(ies) available for tezosentan and dobutamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010