Page last updated: 2024-09-04

tezosentan and cyclic gmp

tezosentan has been researched along with cyclic gmp in 2 studies

Compound Research Comparison

Studies (tezosentan)	Trials (tezosentan)	Recent Studies (post-2010) (tezosentan)	Studies (cyclic gmp)	Trials (cyclic gmp)	Recent Studies (post-2010) (cyclic gmp)
157	29	33	22,346	333	4,062

Protein Interaction Comparison

Protein	Taxonomy	cyclic gmp (IC50)
Phosphodiesterase	Bos taurus (cattle)	0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	2.4

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bender, SB; de Beer, VJ; de Wijs-Meijler, D; Duncker, DJ; Hoekstra, M; Laughlin, MH; Merkus, D; Zhou, Z	1
Bender, SB; de Beer, VJ; Duncker, DJ; Jan Danser, AH; Laughlin, MH; Merkus, D; Zhou, Z	1

Other Studies

2 other study(ies) available for tezosentan and cyclic gmp

Article	Year
Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity. American journal of physiology. Lung cellular and molecular physiology, 2014, Mar-01, Volume: 306, Issue:5 Topics: Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Female; Humans; Male; Phosphodiesterase 5 Inhibitors; Physical Conditioning, Animal; Pulmonary Circulation; Pyridines; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Sus scrofa; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	2014
Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is mediated in part via an increase in endothelin production. American journal of physiology. Heart and circulatory physiology, 2014, Volume: 306, Issue:6 Topics: Animals; Consciousness; Coronary Vessels; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelins; Endothelium, Vascular; Female; Male; Models, Animal; Physical Conditioning, Animal; Pyridines; Rest; Swine; Tetrazoles; Vascular Resistance; Vasoconstriction	2014

Article

Year

Pulmonary vasoconstrictor influence of endothelin in exercising swine depends critically on phosphodiesterase 5 activity.

American journal of physiology. Lung cellular and molecular physiology, 2014, Mar-01, Volume: 306, Issue:5

Topics: Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Synergism; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Female; Humans; Male; Phosphodiesterase 5 Inhibitors; Physical Conditioning, Animal; Pulmonary Circulation; Pyridines; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Sus scrofa; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents

2014

Phosphodiesterase-5 activity exerts a coronary vasoconstrictor influence in awake swine that is mediated in part via an increase in endothelin production.

American journal of physiology. Heart and circulatory physiology, 2014, Volume: 306, Issue:6

Topics: Animals; Consciousness; Coronary Vessels; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelins; Endothelium, Vascular; Female; Male; Models, Animal; Physical Conditioning, Animal; Pyridines; Rest; Swine; Tetrazoles; Vascular Resistance; Vasoconstriction

2014