Page last updated: 2024-09-04

tezosentan and avosentan

tezosentan has been researched along with avosentan in 2 studies

Compound Research Comparison

Studies
(tezosentan)
Trials
(tezosentan)
Recent Studies (post-2010)
(tezosentan)
Studies
(avosentan)
Trials
(avosentan)
Recent Studies (post-2010) (avosentan)
1572933291015

Protein Interaction Comparison

ProteinTaxonomytezosentan (IC50)avosentan (IC50)
Endothelin receptor type BHomo sapiens (human)0.9
Endothelin-1 receptorHomo sapiens (human)0.0023

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bolli, MH; Boss, C; Gatfield, J1
Cheng, G; Li, B; Li, Y; Liu, D; Lu, S; Xiao, J; Yuan, W; Zhao, Z1

Reviews

2 review(s) available for tezosentan and avosentan

ArticleYear
From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective.
    Bioorganic & medicinal chemistry letters, 2016, 08-01, Volume: 26, Issue:15

    Topics: Bosentan; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Humans; Molecular Structure; Pyrimidines; Receptors, Endothelin; Structure-Activity Relationship; Sulfonamides

2016
Endothelin-receptor antagonist can reduce blood pressure in patients with hypertension: a meta-analysis.
    Blood pressure, 2017, Volume: 26, Issue:3

    Topics: Antihypertensive Agents; Atrasentan; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Bosentan; Endothelin Receptor Antagonists; Humans; Hypertension; Middle Aged; Models, Statistical; Phenylpropionates; Pyridines; Pyrimidines; Pyrrolidines; Randomized Controlled Trials as Topic; Sulfonamides; Survival Analysis; Tetrazoles

2017