Compounds > tezosentan
Page last updated: 2024-09-04

tezosentan and avapro

tezosentan has been researched along with avapro in 4 studies

Compound Research Comparison

Studies
(tezosentan)		Trials
(tezosentan)		Recent Studies (post-2010)
(tezosentan)		Studies
(avapro)		Trials
(avapro)		Recent Studies (post-2010) (avapro)
15729331,369385495

Protein Interaction Comparison

ProteinTaxonomytezosentan (IC50)avapro (IC50)
Bile salt export pumpHomo sapiens (human)7.3067
Type-1 angiotensin II receptorHomo sapiens (human)0.0099
Type-2 angiotensin II receptorHomo sapiens (human)0.003

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Boomsma, F; de Beer, VJ; Dekkers, DH; Duncker, DJ; Lamers, JM; Merkus, D; Pijnappels, DA; Sorop, O1
de Beer, VJ; de Graaff, HJ; Duncker, DJ; Hoekstra, M; Merkus, D1

Other Studies

4 other study(ies) available for tezosentan and avapro

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Integrative control of coronary resistance vessel tone by endothelin and angiotensin II is altered in swine with a recent myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Hemodynamics; Irbesartan; Myocardial Infarction; Oxygen; Physical Exertion; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Tetrazoles; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Ventricular Function, Left; Ventricular Remodeling

2008
Integrated control of pulmonary vascular tone by endothelin and angiotensin II in exercising swine depends on gender.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Endothelin Receptor Antagonists; Endothelins; Female; Irbesartan; Male; Models, Animal; Physical Conditioning, Animal; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Endothelin; Sex Characteristics; Swine; Tetrazoles; Vasoconstriction; Vasodilator Agents

2010