Compounds > tetraphenylphosphonium
Page last updated: 2024-09-05

tetraphenylphosphonium and nicardipine

tetraphenylphosphonium has been researched along with nicardipine in 3 studies

Compound Research Comparison

Studies
(tetraphenylphosphonium)		Trials
(tetraphenylphosphonium)		Recent Studies (post-2010)
(tetraphenylphosphonium)		Studies
(nicardipine)		Trials
(nicardipine)		Recent Studies (post-2010) (nicardipine)
4380392,646444312

Protein Interaction Comparison

ProteinTaxonomytetraphenylphosphonium (IC50)nicardipine (IC50)
Bile salt export pumpHomo sapiens (human)8.314
ATP-dependent translocase ABCB1Mus musculus (house mouse)8
ATP-dependent translocase ABCB1Homo sapiens (human)4.2992
Cytochrome P450 3A4Homo sapiens (human)0.42
Cytochrome P450 2C9 Homo sapiens (human)1.69
ATP-dependent translocase ABCB1Mus musculus (house mouse)2.5
Cytochrome P450 2J2Homo sapiens (human)1.69
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)4.925
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.8

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Ambudkar, SV; Gottesman, MM; Hrycyna, CA; Pastan, I; Ramachandra, M1
Konings, WN; Koole, LA; Putman, M; van Veen, HW1

Other Studies

3 other study(ies) available for tetraphenylphosphonium and nicardipine

ArticleYear
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.
    Molecular biology of the cell, 1996, Volume: 7, Issue:10

    Topics: 3T3 Cells; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Bone Neoplasms; Cell Membrane; Colchicine; Drug Resistance, Multiple; Genetic Vectors; Humans; Mice; Nicardipine; Onium Compounds; Organophosphorus Compounds; Osteosarcoma; Point Mutation; Prazosin; Recombinant Fusion Proteins; Rhodamine 123; Rhodamines; Transfection; Tumor Cells, Cultured; Vaccinia virus; Verapamil; Vinblastine

1996
The secondary multidrug transporter LmrP contains multiple drug interaction sites.
    Biochemistry, 1999, Oct-19, Volume: 38, Issue:42

    Topics: Bacterial Proteins; Benzimidazoles; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Fluorescent Dyes; Kinetics; Lactococcus lactis; Lipid Bilayers; Membrane Proteins; Membrane Transport Proteins; Nicardipine; Onium Compounds; Organophosphorus Compounds; Phospholipids; Quinine; Spectrometry, Fluorescence; Verapamil; Vinblastine; Vincristine

1999