tetramethylrhodamine and malachite-green

Color bind: We have developed a probe TMR-para-MG that switches its fluorescence emission upon binding to a fluorogen-activating protein (FAP). In cells that express FAP, this dye labels target sites in one color and mitochondria in another color, thus it might be a suitable tool for monitoring changes in mitochondrial membrane potential.

Topics: Color; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Membrane Proteins; Mitochondria; Models, Molecular; Molecular Structure; Rhodamines; Rosaniline Dyes; Spectrometry, Fluorescence