Compounds > tetramethylpyrazine
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tetramethylpyrazine and verapamil

tetramethylpyrazine has been researched along with verapamil in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Ai, Y; Ding, K; Huang, Z; Kang, F; Lai, Y; Li, J; Peng, S; Ren, C; Tian, J; Zhang, Y; Zhu, B1
Hu, YP; Lin, J; Wang, QD; Yie, QX; Zhang, TM1
He, J; Liu, XL; Peng, WX; Song, J; Tang, J; Xu, P1
Cheng, Y; Shen, P; Zhou, C1

Other Studies

5 other study(ies) available for tetramethylpyrazine and verapamil

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery of New Monocarbonyl Ligustrazine-Curcumin Hybrids for Intervention of Drug-Sensitive and Drug-Resistant Lung Cancer.
    Journal of medicinal chemistry, 2016, Mar-10, Volume: 59, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Lung Neoplasms; Mice; Molecular Structure; Neoplasms, Experimental; Pyrazines; Reactive Oxygen Species; Structure-Activity Relationship; Thioredoxin-Disulfide Reductase

2016
[Reversal of adriamycin resistance by verapamil and ligustrazini in mouse Ehrlich ascites cancer].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1993, Volume: 28, Issue:1

    Topics: Animals; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Doxorubicin; Drug Resistance; Drug Synergism; Female; Glutathione Transferase; Male; Mice; Pyrazines; Tumor Cells, Cultured; Verapamil

1993
[The effect of tetramethylpyrazine on the pharmacokinetics of intragastrically administered cyclosporine A in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:9

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Calcium Channel Blockers; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Routes; Immunosuppressive Agents; Ligusticum; Male; Plants, Medicinal; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Stomach; Verapamil

2006
Quantitative study of the drug efflux kinetics from sensitive and MDR human breast cancer cells.
    Biochimica et biophysica acta, 2007, Volume: 1770, Issue:7

    Topics: Antibiotics, Antineoplastic; Biological Transport; Breast Neoplasms; Calcium Channel Blockers; Cell Line, Tumor; Diffusion; Doxorubicin; Drug Resistance, Multiple; Female; Humans; Kinetics; Microelectrodes; Models, Biological; Pyrazines; Verapamil

2007