tetramethylpyrazine has been researched along with ferulic acid in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 15 (48.39) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, K; Chen, KJ | 1 |
| Li, YK; Liang, ZJ; Xu, J | 1 |
| Wang, Z | 1 |
| Ozaki, Y | 1 |
| Ma, JP; Ozaki, Y | 1 |
| Huang, X; Niu, G; Ren, P; Wang, Y; Wen, A; Zang, Y | 1 |
| Hou, J; Li, G; Wei, T; Xin, W; Yu, S; Zhang, Z | 1 |
| Zhang, BT | 1 |
| Yue, XF; Zhang, YN; Zhang, ZQ | 1 |
| Gao, Y; Guo, P; Li, YF; Liang, QD; Ma, BP; Ma, ZC; Tan, HL; Tan, W; Wang, SQ; Zhou, Z | 1 |
| Chan, CC; Chang, Y; Chao, FP; Chao, HM; Chi, CW; Ho, LT; Hsu, WM; Kuo, CD; Lee, FL; Lee, SM; Lin, DE; Liu, TY; Lui, WY; Pan, WH | 1 |
| Liu, FJ; Liu, SW; Shi, QX; Sun, LY; Tong, LQ; Yan, YP; Zhu, CF | 1 |
| Cao, J; Gao, YF; Liu, K | 1 |
| Chen, G; Feng, B; Xu, X; Zhang, J | 2 |
| Chen, X; Du, S; Lu, Y; Xu, B; Yao, Z | 1 |
| Chen, Z; Fei, P; Shuai, L; Wang, Q; Yang, T | 1 |
| Ding, G; Jin, Y; Wang, Z; Xiao, W; Yan, R; Yang, Y; Zeng, M; Zhang, J | 1 |
| Chen, G; Chen, Y; Shang, F; Tang, Q; Wang, X; Xu, X; Yang, Y; Zhang, J | 1 |
| Ba, WQ; Fan, WT; Li, Z; Liao, FY; Liao, WG; Wang, D; Wang, LS; Wu, YA; Yu, JY | 1 |
| Hu, PY; Liu, D; Wu, B; Yang, M; Yue, PF; Zhang, GS; Zheng, Q | 1 |
| Chen, ML; Cui, YJ; He, GW; Liu, B; Wu, YL; Xu, SH; Yang, D; Yin, MS; Zhou, PP | 1 |
| Ba, W; Fan, W; Guo, Z; Li, Z; Liao, F; Liao, W; Wang, D; Wang, L; Wu, Y; Yu, J | 1 |
| Chu, Z; Fan, G; Hang, T; He, G; Huang, J; Jiang, J; Yang, G; Zhao, X | 1 |
| Chen, J; Chen, L; Chen, Y; Ge, H; Liang, X; Tian, J | 1 |
| Deng, KW; He, FY; Liao, Q; Liu, WL; Tang, Y; Xiao, MF; Yang, YT; Zhang, YT; Zhou, YQ | 1 |
| Chen, Q; Chen, XJ; Feng, S; Shang, FH; Xu, XY; Zhang, JF | 1 |
| Cheng, H; Guo, S; Ke, G; Liu, M; Mao, Y; Mi, Y; Wang, M; Wei, P | 1 |
| Cheng, H; Li, S; Liu, M; Mi, Y; Wang, M | 1 |
| Hu, S; Li, Q; Pan, F; Song, X; Sun, B; Sun, J; Tuersuntuoheti, T; Zhao, F; Zheng, F; Zhu, L | 1 |
| Chen, Y; Dai, XS; Ding, Y; Guo, X; Li, C; Wei, QH; Xu, XY; Yang, XQ; Zhang, YX | 1 |
3 review(s) available for tetramethylpyrazine and ferulic acid
| Article | Year |
|---|---|
Ischemic stroke treated with Ligusticum chuanxiong.
Topics: Animals; Cerebrovascular Disorders; Coumaric Acids; Drugs, Chinese Herbal; Humans; Platelet Aggregation Inhibitors; Pyrazines | 1992 |
[Mechanism on modulating platelet function of activating blood circulation and removing stasis herbs].
Topics: Blood Platelets; Calcium-Transporting ATPases; Calmodulin; Coumaric Acids; Drug Combinations; Drugs, Chinese Herbal; Humans; Phenanthrolines; Plant Extracts; Platelet Aggregation Inhibitors; Pyrazines; Salvia miltiorrhiza | 1992 |
[Progress on TCM drug-therapy of antagonizing arteriosclerosis].
Topics: Arteriosclerosis; Coumaric Acids; Drugs, Chinese Herbal; Flavonoids; Humans; Phenols; Phytotherapy; Polymers; Polyphenols; Pyrazines | 2003 |
28 other study(ies) available for tetramethylpyrazine and ferulic acid
| Article | Year |
|---|---|
[Effects of tetramethylpyrazine and ferulic acid alone or combined on vascular smooth muscle, blood viscosity and toxicity].
Topics: Animals; Aorta; Blood Viscosity; Coronary Circulation; Coumaric Acids; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Pyrazines; Rabbits; Rats; Rats, Sprague-Dawley | 1992 |
Antiinflammatory effect of tetramethylpyrazine and ferulic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coumaric Acids; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred Strains; Pyrazines; Rats; Rats, Inbred Strains | 1992 |
Inhibitory effects of tetramethylpyrazine and ferulic acid on spontaneous movement of rat uterus in situ.
Topics: Animals; Coumaric Acids; Female; In Vitro Techniques; Pyrazines; Rats; Rats, Inbred Strains; Uterine Contraction | 1990 |
Effects of tetramethylpyrazine phosphate and sodium ferulate alone or in combination on hemodynamics in anesthetized dog.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Coumaric Acids; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Infusions, Intravenous; Male; Myocardial Contraction; Plant Extracts; Plants, Medicinal; Pyrazines; Vasodilator Agents | 1996 |
Iron-induced oxidative damage and apoptosis in cerebellar granule cells: attenuation by tetramethylpyrazine and ferulic acid.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Coumaric Acids; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Fragmentation; Down-Regulation; Drugs, Chinese Herbal; Enzyme Activation; Gene Expression Regulation; Genes, p53; Iron; Lipid Peroxidation; Neuroprotective Agents; Oxidative Stress; Pyrazines; Rats; Rats, Wistar | 2003 |
[Study on the interactions between four components in Ligusticum chuanxiong rhizome and acceptors on cardiac muscle membrane].
Topics: Animals; Anthraquinones; Cell Membrane; Coumaric Acids; Female; Ligusticum; Male; Myocytes, Cardiac; Plants, Medicinal; Protein Binding; Pyrazines; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rhizome; Vanillic Acid | 2004 |
Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice.
Topics: Animals; Benzoates; Body Weight; Bone Marrow Cells; Bridged-Ring Compounds; Colony-Forming Units Assay; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Radiation; Drugs, Chinese Herbal; Female; Fructose; Gamma Rays; Glucosides; Hematopoietic Stem Cells; Mice; Mice, Inbred C57BL; Monoterpenes; Pyrazines; Radiation-Protective Agents; Stem Cells; Thymus Gland | 2006 |
Ferulic acid, but not tetramethylpyrazine, significantly attenuates retinal ischemia/reperfusion-induced alterations by acting as a hydroxyl radical scavenger.
Topics: Animals; Coumaric Acids; Electroretinography; Free Radical Scavengers; Hydroxyl Radical; Immunohistochemistry; Ischemia; Neuroprotective Agents; Pyrazines; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Retina; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
[Determination and fingerprint analysis of tetramethylpyrazine and ferulic acid in Ligusticum chuanxiong].
Topics: Chromatography, High Pressure Liquid; Coumaric Acids; Drug Contamination; Ligusticum; Plants, Medicinal; Pyrazines; Quality Control; Rhizome; Seasons | 2008 |
[Effect of Ligusticum and its two main components on muscle atrophy in a hind limb unloaded rat model].
Topics: Animals; Coumaric Acids; Drugs, Chinese Herbal; Extremities; Female; Hemorheology; Hindlimb Suspension; Ligusticum; Muscle Fibers, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley | 2010 |
[Comparative study on pharmacokinetics of tetramethylpyrazine, ferulic acid and their compatibility].
Topics: Animals; Area Under Curve; Calibration; Coumaric Acids; Female; Linear Models; Pyrazines; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2010 |
[Simultaneous determination of five effective components in Rhizoma Chuanxiong by RP-HPLC].
Topics: 4-Butyrolactone; Benzofurans; Calibration; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Pyrazines | 2010 |
[Effect of different compatibility of tetramethylpyrazine on its pharmacokinetics in vivo].
Topics: Animals; Chromatography, High Pressure Liquid; Coumaric Acids; Diterpenes; Drug Interactions; Female; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Spectroscopic analysis on the interaction of ferulic acid and tetramethylpyrazine with trypsin.
Topics: Circular Dichroism; Coumaric Acids; Molecular Docking Simulation; Pyrazines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Trypsin | 2014 |
An automated dual-gradient liquid chromatography-MS/MS method for the simultaneous determination of ferulic acid, ligustrazine and ligustilide in rat plasma and its application to a pharmacokinetic study.
Topics: 4-Butyrolactone; Absorption; Administration, Oral; Animals; Automation; Calibration; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumaric Acids; Male; Medicine, Chinese Traditional; Plant Extracts; Pressure; Pyrazines; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sulfamethoxazole; Tandem Mass Spectrometry | 2014 |
Combination use of ferulic acid, ligustrazine and tetrahydropalmatine inhibits the growth of ectopic endometrial tissue: a multi-target therapy for endometriosis rats.
Topics: Animals; Berberine Alkaloids; Choristoma; Coumaric Acids; Drug Therapy, Combination; Endometriosis; Endometrium; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; I-kappa B Proteins; Interleukin-1beta; Luteinizing Hormone; Macrophages, Peritoneal; NF-KappaB Inhibitor alpha; Phagocytosis; Pyrazines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2014 |
[Study on recovery and its influencing factors of ferulic acid and tetramethylpyrazine in cerebral microdialysis probe].
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Humans; Microdialysis; Pyrazines; Rats | 2015 |
Pharmacokinetic comparative study of gastrodin after oral administration of Gastrodia elata Bl. extract and its compatibility with the different indigents of Ligusticum chuanxiong Hort. to rats.
Topics: Administration, Oral; Alkaloids; Animals; Area Under Curve; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coumaric Acids; Drug Interactions; Female; Gastrodia; Glucosides; Half-Life; Hydroxybenzoates; Ligusticum; Metabolic Clearance Rate; Phytotherapy; Plant Extracts; Plants, Medicinal; Pyrazines; Rats, Wistar | 2016 |
Tetramethylpyrazine-2'-O-sodium ferulate attenuates blood-brain barrier disruption and brain oedema after cerebral ischemia/reperfusion.
Topics: Animals; Aquaporin 4; Behavior, Animal; Blood-Brain Barrier; Brain; Brain Edema; Cell Adhesion Molecules; Coumaric Acids; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Occludin; Pyrazines; Rats, Sprague-Dawley; Reperfusion Injury | 2017 |
Microdialysis combined with UPLC-MS/MS method for determination of tetramethylpyrazine and ferulic acid in striatum of awake and anesthetic rats subjected to cerebral ischemia.
Topics: Animals; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Corpus Striatum; Coumaric Acids; Drug Synergism; Limit of Detection; Male; Microdialysis; Pyrazines; Rats; Reperfusion Injury; Sensitivity and Specificity; Tandem Mass Spectrometry | 2016 |
Profiling and Preparation of Metabolites from Pyragrel in Human Urine by Online Solid-Phase Extraction Coupled with High Performance Liquid Chromatography Tandem Mass Spectrometry Followed by a Macroporous Resin-Based Purification Approach.
Topics: Chromatography, High Pressure Liquid; Coumaric Acids; Humans; Metabolomics; Pyrazines; Solid Phase Extraction; Tandem Mass Spectrometry; Urine | 2017 |
Evaluation of antioxidant activities of ethanol extract from Ligusticum subjected to in-vitro gastrointestinal digestion.
Topics: Antioxidants; Coumaric Acids; Digestion; Ethanol; Gastrointestinal Tract; Ligusticum; Oxidative Stress; Plant Extracts; Polyphenols; Pyrazines; Reference Standards | 2018 |
Application of TQSM polypharmacokinetics and its similarity approach to ascertain Q-marker by analyses of transitivity in vivo of five candidates in Buyanghuanwu injection.
Topics: Amygdalin; Animals; Biological Availability; Biomarkers; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Glucosides; Injections; Monoterpenes; Pyrazines; Rats, Wistar; Saponins; Triterpenes | 2018 |
[In vitro inhibitory effects of Jiawei Foshou San capsule on activity of cytochrome P450 enzymes in rat and human liver microsomes].
Topics: Animals; Berberine Alkaloids; Coumaric Acids; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drugs, Chinese Herbal; Humans; Liver; Microsomes, Liver; Pyrazines; Rats | 2016 |
Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood-Brain Barrier; Cold Temperature; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Extracellular Fluid; Gastrodia; Glucosides; Humans; Ligusticum; Male; Microdialysis; Migraine Disorders; Permeability; Pyrazines; Rats; Specific Pathogen-Free Organisms; Vasoconstriction | 2020 |
Pharmacokinetic comparative study of GAS with different concentration of tetramethylpyrazine and ferulic acid on liver-yang hyperactivity migraine model by blood-brain microdialysis method.
Topics: Animals; Benzyl Alcohols; Brain; Coumaric Acids; Glucosides; Liver; Microdialysis; Migraine Disorders; Pyrazines | 2020 |
Interaction mechanism of kafirin with ferulic acid and tetramethyl pyrazine: Multiple spectroscopic and molecular modeling studies.
Topics: Coumaric Acids; Molecular Docking Simulation; Pyrazines; Sorghum | 2021 |
Ferulic acid, ligustrazine, and tetrahydropalmatine display the anti-proliferative effect in endometriosis through regulating Notch pathway.
Topics: Cell Proliferation; Endometriosis; Female; Humans; Jagged-1 Protein; Ki-67 Antigen; Platelet Aggregation Inhibitors; Proliferating Cell Nuclear Antigen; Receptors, Notch; Signal Transduction | 2023 |