Page last updated: 2024-08-24

tetraiodothyroacetic acid and thyroxine

tetraiodothyroacetic acid has been researched along with thyroxine in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (20.87)	18.7374
1990's	7 (6.09)	18.2507
2000's	21 (18.26)	29.6817
2010's	52 (45.22)	24.3611
2020's	11 (9.57)	2.80

Authors

Authors	Studies
Arsequell, G; Blasi, D; Bosch, L; Centeno, NB; Cotrina, EY; Pinto, M; Planas, A; Quintana, J; Valencia, G; Vilà, M	1
Arifi, S; Bischoff, I; Chaikuad, A; Fürst, R; Gellrich, L; Goebel, T; Heering, J; Heitel, P; Kahnt, A; Kilu, W; Knapp, S; Merk, D; Paulke, A; Pogoda, W; Pollinger, J; Proschak, E; Schubert-Zsilavecz, M; Steinhilber, D; Wurglics, M	1
Braverman, L; Burger, A; Nicod, P; Suter, P; Vagenakis, P; Vallotton, MB	1
Crossley, DN; Ramsden, DB	2
Carter, PJ; Hoffenberg, R; Ramsden, DB; Raw, PJ	1
Chopra, IJ; Kannan, R; Ookhtens, M; Singh, BN	1
De, S; Medda, AK; Ray, AK	1
Aranda, A; Montiel, F; Ortiz-Caro, J; Pascual, A; Villa, A; Yusta, B	1
Burger, AG; Engler, D	1
Sorimachi, K; Yasumura, Y	1
Cahnmann, HJ; van der Walt, B	1
Felt, V; Ploc, I	1
Burger, A; Chambers, JB; Pittman, CS; Shimizu, T	1
Rapoport, B; Takai, NA; Yamamoto, M	1
de Jong, M; Docter, R; Everts, ME; Hennemann, G; Krenning, EP; Moerings, EP; Tempelaars, AM; van Toor, H; Visser, TJ	1
de Jong, M; Docter, R; Everts, ME; Hennemann, G; Krenning, EP; Moerings, EP; van Koetsveld, PM; Visser, TJ	1
Blas, SD; Cody, V; Davis, FB; Davis, PJ; Galindo, J; Warnick, PR	1
Carlin, K; Carlin, S	1
Bhagavan, NV; Ha, CE; Harohalli, K; Park, D; Petersen, CE	1
Davis, FB; Davis, PJ; Gordinier, JK; Lin, HY; Martino, LJ; Wilcox, BD	1
Burger, A; Lameloise, N; O'Connell, M; Siegrist-Kaiser, C	1
Davis, FB; Davis, PJ; Lin, HY; Shih, A	1
Cody, V; Luft, JR; Muzioł, T; Pangborn, W; Wojtczak, A	1
Everts, ME; Hennemann, G; Lamers, JM; Van der Putten, HH; Verhoeven, FA; Visser, TJ	1
GOOLDEN, AW	1
BARAC, G; CARLIER, J	1
ALBRIGHT, EC; LARDY, HA; LARSON, FC; TOMITA, K	1
FARKAS, M; VARNAI, I	1
BRONK, JR	1
FOERSTER, W; SCHRUMPF, W	1
BOLLMAN, JL; FLOCK, EV; STOBIE, GH	1
GREEN, WL; INGBAR, SH	1
TIERNEY, J; VOLPERT, EM; WERNER, SC	1
EZRIN, C; JOHNSTON, M; ROW, VV; VOLPE, R	1
CRISPELL, KR; HARRAH, JD; OLICHNEY, MJ	1
JACOB, A	1
Davis, FB; Davis, PJ; Lin, HY; Tang, HY; Zhang, S	1
Cao, HJ; Davis, FB; Davis, PJ; Lin, HY; Mohamed, S; Mousa, SA; O'Connor, L	1
Bergh, JJ; Davis, FB; Davis, PJ; Lansing, L; Lin, HY; Mohamed, SN; Mousa, S	1
Bergh, JJ; Davis, FB; Davis, PJ; Mousa, SA; O'Connor, LJ; Scanlan, TS	1
Cody, V; Neumann, P; Wojtczak, A	1
Davis, FB; Davis, PJ; Mousa, SA; O'Connor, L	1
Davis, FB; Davis, PJ; Fenstermaker, RA; Hercbergs, A; Keating, T; Lansing, L; Lin, HY; Mousa, A; Mousa, SA; Shih, A; Tang, HY	1
Davis, FB; Davis, PJ; Feng, X; Mohamed, S; Mousa, SA	1
Aljada, A; Bergh, JJ; Davis, FB; Davis, PJ; Dier, E; Dyskin, E; Lin, HY; Mousa, SA; O'Connor, LJ; Rebbaa, A; Yalcin, M	1
Chu, F; Davis, FB; Davis, PJ; Mousa, SA; Rebbaa, A	1
Ribera, AB; Yonkers, MA	1
Chehín, RN; Cortez, LM; Farías, RN	1
Bridoux, A; Cui, H; Dyskin, E; Mousa, SA; Yalcin, M	1
Cao, HJ; Davis, FB; Davis, PJ; Lin, HY; Luidens, MK	1
Ciesielski, MJ; Davis, FB; Davis, PJ; Hercbergs, A; Leith, JT	1
Davis, FB; Davis, PJ; Glinskii, AB; Glinsky, GV; Hercbergs, AH; Lin, HY; Luidens, MK; Mousa, SA; Sun, M; Tang, HY	1
Bharali, DJ; Davis, FB; Davis, PJ; Dyskin, E; Hercbergs, A; Lansing, L; Mousa, SA; Mousa, SS; Yalcin, M	1
Davis, FB; Davis, PJ; Mousa, SA; Mousa, SS	1
Bharali, DJ; Bridoux, A; Davis, FB; Davis, PJ; Dyskin, E; Glinskii, A; Glinsky, GV; Hercbergs, AH; Lansing, L; Lin, HY; Ma, J; Mousa, SA; Mousa, SS; Yalcin, M	1
Bharali, DJ; Davis, FB; Davis, PJ; Dier, E; Dyskin, E; Lansing, L; Mousa, SA; Mousa, SS; Yalcin, M	1
Davis, FB; Davis, PJ; Lin, HY; Luidens, MK; Mousa, SA	1
Davis, FB; Davis, PJ; Hercbergs, AH; Leith, JT; Lin, HY	1
Brown, D; Davis, FB; Davis, PJ; Drusano, GL; Kulawy, R; Landersdorfer, CB; Lim, CU; Lin, C; Lin, HY; Lin, S; London, D; Louie, A; Meng, R; Mousa, SA; Queimado, L; Tang, HY; Van Scoy, B	1
Bertrand, S; Cravedi, JP; Delous, G; Escriva, H; Hillenweck, A; Laudet, V; Paris, M; Zalko, D	1
Friesema, EC; Klootwijk, W; Visser, TJ	1
Bharali, DJ; Davis, FB; Davis, PJ; Lin, HY; Meng, R; Mousa, SA; Tang, HY; Yalcin, M	1
Duh, EJ; Gong, J; Wei, Y; Xu, Z; Yoshida, T	1
Cao, JH; Davis, FB; Davis, PJ; Hercbergs, A; Lin, HY; London, D; Luidens, M; Meng, R; Mousa, SA; Tang, HY; Westfall, J	1
Choi, Y; Han, SE; Kim, CW; Kim, J; Kim, K; Kim, S; Kim, YB; Kwon, IC; Lee, S; Oh, YK; Shim, G	1
Ishibashi, H; Nabekura, J; Nielsen, M; Witt, MR	1
Gonçalves, R; Silva, FR; Zamoner, A; Zanatta, AP; Zanatta, L	1
Ackermann, T; Groba, C; Heuer, H; Horn, S; Kersseboom, S; Mayerl, S; Müller, J; Trajkovic-Arsic, M; Visser, TJ	1
Bharali, DJ; Davis, PJ; Mousa, SA; Yalcin, M	1
Bharali, DJ; Davis, FB; Davis, PJ; Lin, HY; Meng, R; Mousa, SA; Stain, SC; Sudha, T; Tang, HY; Yalcin, M	1
Davis, FB; Davis, PJ; Glinsky, GV; Hercbergs, A; Incerpi, S; Lin, HY; Luidens, MK; Mousa, SA; Tang, HY	1
Choe, YS; Kang, CM; Koo, HJ; Lee, KC; Lee, S; Oh, YK	1
Barbakadze, T; Mikeladze, D; Natsvlishvili, N	1
Cioffi, F; de Lange, P; Goglia, F; Lanni, A; Senese, R	1
Heuer, H; Huttner, WB; Stenzel, D; Wilsch-Bräuninger, M; Wong, FK	1
Li, L; Liu, X; Shi, YN; Yuan, J; Zheng, N	1
Banegas, I; Carmona-Cortés, J; García-Lora, ÁM; Osuna, A; Quesada, A; Rodríguez-Gómez, I; Vargas, F; Wangensteen, R	1
Banegas, I; Carmona-Cortés, J; García-Lora, AM; Quesada, A; Rodríguez-Gómez, I; Vargas, F; Vargas-Tendero, P; Wangensteen, R	1
Ashur-Fabian, O; Baharal, T; Cohen, K; Davis, PJ; Ellis, M; Erez, D; Flint, N; Hercbergs, A; Shalev, S	1
Carlsen, J; Göke, B; Heuer, H; Müller, AM; Nelson, PJ; Rühland, S; Salb, N; Schmohl, KA; Schwenk, N; Spitzweg, C; Wechselberger, A	1
Kamimori, H; Kinouchi, H; Kitagawa, H; Matsuyama, K	1
Chin, YT; Davis, PJ; Incerpi, S; Lee, YS; Lin, HY; Liu, LF; Lu, YT; Pedersen, JZ; Shih, A; Wei, PL; Wu, HC; Yang, YSH	1
Cui, H; Fu, R; Hu, M; Li, C; Li, M; Li, X; Li, Z; Lu, L; Luo, M; Sheng, F; Shi, S; Wu, G; Xiang, M; Xu, J; Zhang, Q; Zhou, M	1
Darwish, NH; Davis, PJ; Mousa, SA; Rajabi, M; Sudha, T	1
Davis, PJ; Glinsky, GV; Lin, HY; Mousa, SA	1
Chen, L; Li, X; Song, Y; Sun, Y; Xiao, Y; Xing, Y; Zhang, P	1
Atkins, S; Fernando, R; Niziol, LM; Placzek, AT; Placzek, E; Raychaudhuri, N; Reese, EA; Scanlan, TS; Schwartz, S; Smith, TJ; Trierweiler, A	1
Bayar, Y; Bitiktaş, S; Dursun, N; Kavraal, Ş; Süer, C; Tan, B; Yousef, M	1
Davis, PJ; Hercbergs, AA; Leith, JT; Mousa, SA	1
Groeneweg, S; Peeters, RP; Visser, TJ; Visser, WE	1
Bharali, DJ; Darwish, NH; Davis, PJ; Debreli Coskun, M; Keating, KA; Lin, HY; Mousa, SA; Sudha, T; Yalcin, M	1
Bharali, DJ; Darwish, NHE; Davis, PJ; Mousa, SA; Sell, S; Sudha, T	1
Abnous, K; Alibolandi, M; Farzad, SA; Ramezani, M; Rezvani, R; Taghdisi, SM	1
Bennett, JA; Changou, CA; Chen, YR; Chin, YT; Davis, PJ; Fu, E; Ho, Y; Incerpi, S; Li, WS; Lin, CY; Lin, HY; Liu, LF; Mousa, SA; Nana, AW; Pedersen, JZ; Shih, YJ; Whang-Peng, J	1
Hong, Y; Hu, F; Huang, X; Liu, X; Meng, T; Tan, Y; Yang, X; Yuan, H; Zhao, Y; Zhu, Y	1
Mousa, SA; Rajabi, M; Yalcin, M	1
Davis, PJ; Hercbergs, A; Kenney, S; Leith, JT; Mousa, SA	1
Abnous, K; Alibolandi, M; Amel Farzad, S; Kalalinia, F; Mohammadi, M; Ramezani, M; Taghdisi, SM	1
Davis, PJ; Lin, HY; Mousa, SA	1
Chen, YR; Chin, YT; Chou, SY; Davis, PJ; Fu, E; Ho, Y; Lee, SY; Lim, YT; Lin, HY; Lin, SJ; Nana, AW; Sh Yang, YC; Shih, YJ; Su, KW; Wang, K; Whang-Peng, J	1
Gershengorn, MC; Krieger, CC; Neumann, S	1
Fernando, R; Scanlan, TS; Smith, TJ	1
Nelson, PJ; Schmohl, KA; Spitzweg, C	1
Rutigliano, G; Saponaro, F; Zucchi, R	1
Müller, AM; Nelson, PJ; Schmohl, KA; Spitzweg, C	1
Ahn, J; Choe, YS; Choi, JY; Kim, BT; Kim, H; Kim, JY; Koo, HJ; Lee, KH	1
de Oliveira, M; De Sibio, MT; Deprá, I; Gonçalves, BM; Mathias, LS; Moretto, FCF; Nogueira, CR; Olimpio, RMC; Rodrigues, BM; Tilli, HP	1
Li, J; Li, N; Liu, H; Yang, J; Zuo, R	1
Chang, WJ; Chen, YR; Chin, YT; Chu, HR; Davis, PJ; De Vito, P; Gionfra, F; Hsiung, CN; Huang, CH; Huang, HM; Huang, TY; Incerpi, S; Lee, SY; Li, ZL; Lin, CY; Lin, HY; Pan, YS; Pedersen, JZ; Unson, S; Wang, K; Whang-Peng, J	1
Davis, PJ; Hercbergs, A; Lin, HY; Mousa, SA	1
Davis, PJ; Godugu, K; Mousa, SA; Sudha, T	1
Coskun, MD; Darwish, NHE; Davis, PJ; Mousa, SA; Rehman, MU; Satti, JA; Sudha, T	1
Candelotti, E; ChangOu, CA; Chu, HR; Chung, CC; Davis, PJ; De Luca, R; Huang, CH; Huang, HM; Huang, TY; Incerpi, S; Lee, SY; Li, WS; Li, ZL; Lin, CY; Lin, HY; Pedersen, JZ; Wang, K; Whang-Peng, J; Yang, YSH	1
Davis, PJ; Glinsky, GV; Godugu, K; Lin, HY; Mousa, SA	1

Reviews

10 review(s) available for tetraiodothyroacetic acid and thyroxine

Article	Year
The deiodination of the iodothyronines and of their derivatives in man. Endocrine reviews, 1984,Spring, Volume: 5, Issue:2 Topics: Chemical Phenomena; Chemistry; Diiodothyronines; Diiodotyrosine; Glucuronates; Humans; Hyperthyroidism; Iodine; Kinetics; Phenyl Ethers; Radioimmunoassay; Sulfates; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1984
Membrane receptor for thyroid hormone: physiologic and pharmacologic implications. Annual review of pharmacology and toxicology, 2011, Volume: 51 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Humans; Integrin alphaVbeta3; Nanoparticles; Neoplasms; Signal Transduction; Thyroxine; Triiodothyronine	2011
Molecular mechanisms of actions of formulations of the thyroid hormone analogue, tetrac, on the inflammatory response. Endocrine research, 2013, Volume: 38, Issue:2 Topics: Cytokines; Humans; Inflammation; Interleukins; Nanoparticles; Receptors, Thyroid Hormone; Thyroxine	2013
Thyroid: biological actions of 'nonclassical' thyroid hormones. The Journal of endocrinology, 2014, Volume: 221, Issue:2 Topics: Animals; Diiodothyronines; Humans; Signal Transduction; Thyroid Gland; Thyroid Hormones; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	2014
Actions of Thyroid Hormone Analogues on Chemokines. Journal of immunology research, 2016, Volume: 2016 Topics: Animals; Chemokines; Chemokines, C; Chemokines, CC; Chemokines, CX3C; Chemokines, CXC; Humans; Receptors, Chemokine; Thyroxine	2016
Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes. Molecular and cellular endocrinology, 2017, Dec-15, Volume: 458 Topics: Biomimetic Materials; Female; Humans; Male; Monocarboxylic Acid Transporters; Mutation; Signal Transduction; Symporters; Thyroid Hormone Receptors beta; Thyroid Hormone Resistance Syndrome; Thyroxine; Triiodothyronine	2017
Tetrac as an anti-angiogenic agent in cancer. Endocrine-related cancer, 2019, 06-01, Volume: 26, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Humans; Mesenchymal Stem Cells; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Thyroxine	2019
Novel thyroid hormones. Endocrine, 2019, Volume: 66, Issue:1 Topics: Animals; Diiodothyronines; Humans; Thyronines; Thyroxine; Triiodothyronine	2019
Thyroid Hormone Effects on Mesenchymal Stem Cell Biology in the Tumour Microenvironment. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2020, Volume: 128, Issue:6-07 Topics: Animals; Humans; Integrin alphaVbeta3; Mesenchymal Stem Cells; Neoplasms; Neovascularization, Pathologic; Thyroid Hormones; Thyroxine	2020
Actions of L-thyroxine (T4) and Tetraiodothyroacetic Acid (Tetrac) on Gene Expression in Thyroid Cancer Cells. Genes, 2020, 07-07, Volume: 11, Issue:7 Topics: Animals; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Leptin; Thyroid Neoplasms; Thyroxine	2020

Other Studies

105 other study(ies) available for tetraiodothyroacetic acid and thyroxine

Article	Year
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation. Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22 Topics: Diflunisal; Flufenamic Acid; Halogenation; Humans; Kinetics; Ligands; Models, Molecular; Prealbumin; Protein Multimerization; Protein Structure, Secondary; Structure-Activity Relationship	2013
l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ. Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13 Topics: Amino Acid Sequence; Animals; Drug Evaluation, Preclinical; Male; Mice; Models, Molecular; PPAR gamma; Protein Conformation; Thyroxine	2020
Reduced active thyroid hormone levels in acute illness. Lancet (London, England), 1976, Mar-27, Volume: 1, Issue:7961 Topics: Acute Disease; Adult; Aged; Bronchitis; Cardiovascular Diseases; Child; Female; Gastroenteritis; Humans; Infectious Mononucleosis; Lung Diseases; Male; Middle Aged; Q Fever; Salmonella Infections; Thyroid Hormones; Thyroxine; Triiodothyronine	1976
Serum tetraiodothyroacetate (T4A) levels in normal healthy euthyroid individuals determined by gas chromatography-mass fragmentography (GC-MF). Clinica chimica acta; international journal of clinical chemistry, 1979, Jun-15, Volume: 94, Issue:3 Topics: Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Microchemistry; Thyroid Gland; Thyroxine	1979
Estimation of tetraiodothyroacetate in human serum. Proceedings of the Royal Society of Medicine, 1975, Volume: 68, Issue:2 Topics: Chromatography, Gas; Humans; Hyperthyroidism; Hypothyroidism; Protein Binding; Thyroxine	1975
Effect of amiodarone on non-deiodinative pathway of thyroid hormone metabolism. Acta endocrinologica, 1990, Volume: 122, Issue:2 Topics: Amiodarone; Animals; Iodide Peroxidase; Male; Metabolic Clearance Rate; Myocardium; Rabbits; Structure-Activity Relationship; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine	1990
Thyroid hormone-induced changes in different ion-specific adenosine triphosphatase activities in liver of Singi fish Heteropneustes fossilis (Bloch). Gegenbaurs morphologisches Jahrbuch, 1986, Volume: 132, Issue:6 Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Catfishes; Liver; Sodium-Potassium-Exchanging ATPase; Thyroid Hormones; Thyroxine; Triiodothyronine	1986
Serum concentrations of 3,5,3',5'-tetraiodothyroacetate (T4A) in subjects with hypo-, hyper- and euthyroidism. Acta endocrinologica, 1986, Volume: 112, Issue:2 Topics: Humans; Hyperthyroidism; Hypothyroidism; Thyroxine; Thyroxine-Binding Proteins	1986
Identification and characterization of L-triiodothyronine receptors in cells of glial and neuronal origin. Endocrinology, 1986, Volume: 119, Issue:5 Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Glioma; Kinetics; Mice; Neuroblastoma; Neuroglia; Neurons; Rats; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	1986
High affinity of triiodothyronine (T3) for nonphenolic ring deiodinase and high affinity of tetraiodothyroacetic acid (TETRAC) for phenolic ring deiodinase in cultured monkey hepatocarcinoma cells and in rat liver homogenates. Endocrinologia japonica, 1981, Volume: 28, Issue:6 Topics: Animals; Cell Line; Chromatography, Ion Exchange; Haplorhini; Iodide Peroxidase; Liver; Liver Neoplasms; Peroxidases; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1981
Synthesis of thyroid hormone metabolites by photolysis of thyroxine and thyroxine analogs in the near UV. Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:5 Topics: Diiodothyronines; Kinetics; Photolysis; Thyroxine; Triiodothyronine, Reverse; Ultraviolet Rays	1982
Effect of theophylline on binding of triiodothyronine, thyroxine, thyroxamine, tetraiodothyroacetic acid and cortisol in the cytosol of human leukocytes. Endokrinologie, 1982, Volume: 79, Issue:2 Topics: Binding Sites; Binding, Competitive; Cytosol; Dextrothyroxine; Humans; Hydrocortisone; Leukocytes; Stereoisomerism; Theophylline; Thyroid Hormones; Thyroxine; Triiodothyronine	1982
The nondeiodinative pathways of thyroxine metabolism: 3,5,3',5-tetraiodothyroacetic acid turnover in normal and fasting human subjects. The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:4 Topics: Adult; Fasting; Humans; Kinetics; Reference Values; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1980
Biliary excretion of iodothyronines in rats as determined by high pressure liquid chromatography: effect of starvation. Endocrinology, 1980, Volume: 107, Issue:1 Topics: Animals; Bile; Chromatography, High Pressure Liquid; Diiodothyronines; Male; Rats; Starvation; Thyronines; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1980
Uptake of 3,3',5,5'-tetraiodothyroacetic acid and 3,3',5'-triiodothyronine in cultured rat anterior pituitary cells and their effects on thyrotropin secretion. Endocrinology, 1995, Volume: 136, Issue:10 Topics: Animals; Blood Proteins; Cells, Cultured; Male; Pituitary Gland, Anterior; Rats; Rats, Wistar; Recombinant Proteins; Thyrotropin; Thyroxine; Triiodothyronine	1995
Uptake of thyroxine in cultured anterior pituitary cells of euthyroid rats. Endocrinology, 1994, Volume: 134, Issue:6 Topics: Animals; Binding, Competitive; Cadaverine; Cell Membrane; Cells, Cultured; Iodine Radioisotopes; Kinetics; Male; Monensin; Oligomycins; Pituitary Gland, Anterior; Rats; Rats, Wistar; Serum Albumin, Bovine; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse	1994
Rabbit skeletal muscle sarcoplasmic reticulum Ca(2+)-ATPase activity: stimulation in vitro by thyroid hormone analogues and bipyridines. Biochimica et biophysica acta, 1993, Dec-12, Volume: 1153, Issue:2 Topics: Animals; Calcium-Transporting ATPases; Cardiotonic Agents; Kinetics; Microsomes; Milrinone; Muscles; Pyridones; Rabbits; Sarcoplasmic Reticulum; Stereoisomerism; Structure-Activity Relationship; Thyronines; Thyroxine; Triiodothyronine	1993
Possible etiology for euthyroid sick syndrome. Medical hypotheses, 1993, Volume: 40, Issue:1 Topics: Animals; Euthyroid Sick Syndromes; Feedback; Gluconeogenesis; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Models, Biological; Thyroxine; Triiodothyronine	1993
Mutagenesis studies of thyroxine binding to human serum albumin define an important structural characteristic of subdomain 2A. Biochemistry, 1997, Jun-10, Volume: 36, Issue:23 Topics: Arginine; Binding Sites; Histidine; Humans; Hyperthyroxinemia; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Thyroxine	1997
Potentiation by thyroid hormone of human IFN-gamma-induced HLA-DR expression. Journal of immunology (Baltimore, Md. : 1950), 1998, Jul-15, Volume: 161, Issue:2 Topics: Biological Transport; Cell Nucleus; Dextrothyroxine; Diiodothyronines; Drug Synergism; Genistein; HeLa Cells; HLA-DR Antigens; Humans; Interferon-gamma; Interferon-Stimulated Gene Factor 3; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Thyroxine; Time Factors; Trans-Activators; Transcription Factors; Triiodothyronine; Triiodothyronine, Reverse; Tyrosine	1998
Differences between the effects of thyroxine and tetraiodothyroacetic acid on TSH suppression and cardiac hypertrophy. European journal of endocrinology, 2001, Volume: 144, Issue:2 Topics: Animals; Calcium-Transporting ATPases; Cardiomegaly; Iodide Peroxidase; Isoenzymes; Liver; Male; Myocardium; Organ Size; Pituitary Gland; Rats; Rats, Inbred Strains; RNA, Messenger; Thyrotropin; Thyroxine	2001
Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinase. Biochemistry, 2001, Mar-06, Volume: 40, Issue:9 Topics: 3T3 Cells; Animals; Cell Fractionation; Cell Line; Cell Nucleus; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nuclear Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Receptors, Thyroid Hormone; Resveratrol; Serine; Stilbenes; Thyroxine; Transfection; Triiodothyronine; Tumor Suppressor Protein p53	2001
Complex of rat transthyretin with tetraiodothyroacetic acid refined at 2.1 and 1.8 A resolution. Acta biochimica Polonica, 2001, Volume: 48, Issue:4 Topics: Animals; Binding Sites; Crystallography, X-Ray; Ligands; Models, Molecular; Prealbumin; Protein Binding; Rats; Thyroxine	2001
Uptake of triiodothyronine and triiodothyroacetic acid in neonatal rat cardiomyocytes: effects of metabolites and analogs. The Journal of endocrinology, 2002, Volume: 173, Issue:2 Topics: Animals; Animals, Newborn; Cell Nucleus; Cells, Cultured; Decamethonium Compounds; Diiodothyronines; Female; Iodine Radioisotopes; Male; Myocardium; Protein Binding; Rats; Rats, Wistar; Thyroxine; Triiodothyronine	2002
The physiological activity of tetraiodothyroacetic acid. Lancet (London, England), 1956, Jun-09, Volume: 270, Issue:6928 Topics: Acetates; Blood; Cholesterol; Thyroxine	1956
[Is tetraiodothyroacetic acid the chemical form of the immediate peripheral action of thyroxin?]. Comptes rendus des seances de la Societe de biologie et de ses filiales, 1956, Volume: 150, Issue:7 Topics: Kidney; Thyronines; Thyroxine	1956
Enzymatic conversion of thyroxine to tetraiodothyroacetic acid and of triiodothyronine to triiodothyroacetic acid. The Journal of biological chemistry, 1957, Volume: 224, Issue:1 Topics: Kidney; Thyroxine; Triiodothyronine	1957
The immediate action of L-thyroxine, L-tetraiodothyroacetic acid, diiodothyronine, diiodothyroacetic acid and L-thyronine on oxygen consumption and body temperature in the hypophysectomized rat; the action of cortisone. Acta physiologica Academiae Scientiarum Hungaricae, 1959, Volume: 15, Issue:2 Topics: Acetates; Animals; Body Temperature; Cortisone; Diiodothyronines; Hypophysectomy; Oxygen Consumption; Rats; Respiration; Thyroid Hormones; Thyronines; Thyroxine	1959
Tetraiodothyroacetic acid, triiodothyroacetic acid and oxidative phosphorylation. Biochimica et biophysica acta, 1959, Volume: 35 Topics: Metabolism; Oxidative Phosphorylation; Thyroxine; Triiodothyronine	1959
[Comparative studies on the influence of triiodthyroacetic acid, tetraiodothyroacetic acid, triiodothyronine and thyroxin on the pulse frequency of isolated rat atrium]. Acta biologica et medica Germanica, 1959, Volume: 3 Topics: Animals; Cardiovascular Physiological Phenomena; Heart; Heart Atria; Heart Rate; Leadership; Rats; Thyroxine; Triiodothyronine	1959
Metabolic pathways of tetraiodothyroacetic acid, triidothyroacetic acid, tetraiodothyropropionic acid and triiodothyropropionic acid. Biochemical pharmacology, 1962, Volume: 11 Topics: Acetates; Biochemical Phenomena; Lipid Metabolism; Metabolic Networks and Pathways; Propionates; Thyroxine; Triiodothyronine	1962
The peripheral metabolism of tri- and tetraiodothyroacetic acids in man. The Journal of clinical endocrinology and metabolism, 1961, Volume: 21 Topics: Thyroxine	1961
Studies with mouse pituitary thyrotropic tumors. VI. Monodeiodination of tetrac. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 112 Topics: Animals; Mice; Pituitary Neoplasms; Thyronines; Thyrotrophs; Thyroxine	1963
LETTER TO THE EDITOR: CHROMATOGRAPHIC IDENTIFICATION OF TETRAIODOTHYROACETIC ACID (TETRAC) IN A HUMAN THYROID NODULE. The Journal of clinical endocrinology and metabolism, 1963, Volume: 23 Topics: Acetates; Chromatography; Diiodotyrosine; Goiter; Humans; Iodides; Thyroid Nodule; Thyroxine; Triiodothyronine; Tyrosine	1963
OBSERVATIONS OF THE EFFECT OF ORGANIC DYES AND DIPHENYLHYDANTOIN ON THE IN VITRO BINDING OF RADIOACTIVE 131-I LABELED L-THYROXINE, L-TRIIODOTHYRONINE AND TETRAIODOTHYROACETIC ACID BY HUMAN ERYTHROCYTES AND SERUM PROTEINS. Acta endocrinologica, 1965, Volume: 48 Topics: Blood Protein Electrophoresis; Blood Proteins; Coloring Agents; Electrophoresis; Erythrocytes; Humans; In Vitro Techniques; Iodine; Iodine Isotopes; Metabolism; Pharmacology; Phenytoin; Thyroxine; Triiodothyronine; Trypan Blue	1965
[Necessity of the transformation of thyroxin into tetraiodothyroacetic acid, previous to its action on tissue respiration in vitro]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1962, Jun-25, Volume: 254 Topics: Cell Respiration; In Vitro Techniques; Metabolism; Thyroxine	1962
Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor. Endocrinology, 2004, Volume: 145, Issue:7 Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Nucleus; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Flavonoids; Humans; MAP Kinase Signaling System; Phosphorylation; Receptors, Estrogen; Serine; Thyroxine	2004
Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circulation research, 2004, Jun-11, Volume: 94, Issue:11 Topics: Animals; Cell Membrane; Chick Embryo; Chorioallantoic Membrane; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Humans; MAP Kinase Signaling System; Neovascularization, Physiologic; Thyroxine	2004
Integrin alphaVbeta3 contains a cell surface receptor site for thyroid hormone that is linked to activation of mitogen-activated protein kinase and induction of angiogenesis. Endocrinology, 2005, Volume: 146, Issue:7 Topics: Animals; Antibodies, Monoclonal; Cell Line; Chick Embryo; Chlorocebus aethiops; Enzyme Activation; Fibroblasts; Integrin alphaVbeta3; Ligands; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Oligopeptides; Receptors, Thyroid Hormone; Thyroxine	2005
The proangiogenic action of thyroid hormone analogue GC-1 is initiated at an integrin. Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:3 Topics: Acetates; Animals; Cell Membrane; Chick Embryo; Chorion; Fibroblast Growth Factor 2; Indicators and Reagents; Integrin alphaVbeta3; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Phenols; Regional Blood Flow; Thyroid Hormone Receptors beta; Thyroxine	2005
Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution. Acta crystallographica. Section D, Biological crystallography, 2005, Volume: 61, Issue:Pt 10 Topics: Animals; Binding Sites; Crystallography, X-Ray; Dimerization; Halogens; Humans; Iodine; Ligands; Macromolecular Substances; Models, Molecular; Molecular Conformation; Phenol; Prealbumin; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rats; Thyroxine	2005
Proangiogenesis action of the thyroid hormone analog 3,5-diiodothyropropionic acid (DITPA) is initiated at the cell surface and is integrin mediated. Endocrinology, 2006, Volume: 147, Issue:4 Topics: Animals; Cell Membrane; Chick Embryo; Diiodothyronines; Fibroblast Growth Factor 2; Humans; Integrin alphaVbeta3; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neovascularization, Physiologic; Propionates; Thyroxine	2006
Acting via a cell surface receptor, thyroid hormone is a growth factor for glioma cells. Cancer research, 2006, Jul-15, Volume: 66, Issue:14 Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Glioma; Integrin alphaVbeta3; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Protein Kinase C; Rats; Thymidine; Thyroxine	2006
Pro-angiogenesis action of thyroid hormone and analogs in a three-dimensional in vitro microvascular endothelial sprouting model. International angiology : a journal of the International Union of Angiology, 2006, Volume: 25, Issue:4 Topics: Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Microcirculation; Neovascularization, Physiologic; Thyroxine; Triiodothyronine	2006
Tetraiodothyroacetic acid, a small molecule integrin ligand, blocks angiogenesis induced by vascular endothelial growth factor and basic fibroblast growth factor. Angiogenesis, 2008, Volume: 11, Issue:2 Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Animals; Cells, Cultured; Chickens; Chorioallantoic Membrane; Endothelial Cells; Endothelium; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Integrins; Ligands; Matrix Metalloproteinases; Mice; Neovascularization, Physiologic; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Thyroxine; Vascular Endothelial Growth Factor A	2008
Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. Angiogenesis, 2008, Volume: 11, Issue:3 Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Humans; Hydroxamic Acids; Mice; Mice, Nude; Neoplasms; Thyroid Hormones; Thyroxine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2008
Sensory neuron sodium current requires nongenomic actions of thyroid hormone during development. Journal of neurophysiology, 2008, Volume: 100, Issue:5 Topics: Animals; Antibodies, Monoclonal; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Embryo, Nonmammalian; In Vitro Techniques; Integrin alphaVbeta3; Models, Biological; Patch-Clamp Techniques; Sensory Receptor Cells; Sodium Channels; Spinal Cord; Thyroid Hormones; Thyroxine; Time Factors; Touch; Zebrafish	2008
Protective effect of 3,5,3'-triiodothyroacetic and 3,5,3',5'-tetraiodothyroacetic acids on serum albumin fibrillation. European biophysics journal : EBJ, 2009, Volume: 38, Issue:7 Topics: Amyloid; Animals; Cattle; Dose-Response Relationship, Drug; Drug Design; Hot Temperature; Kinetics; Protein Binding; Protein Structure, Secondary; Serum Albumin; Spectroscopy, Fourier Transform Infrared; Thyroxine; Triiodothyronine	2009
Semisynthesis and pharmacological activities of Tetrac analogs: angiogenesis modulators. Bioorganic & medicinal chemistry letters, 2009, Jun-15, Volume: 19, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Chick Embryo; Chorioallantoic Membrane; Drug Evaluation, Preclinical; Fibroblast Growth Factors; Hemoglobins; Mice; Structure-Activity Relationship; Thyroxine	2009
Cytoplasm-to-nucleus shuttling of thyroid hormone receptor-beta1 (Trbeta1) is directed from a plasma membrane integrin receptor by thyroid hormone. Endocrine research, 2009, Volume: 34, Issue:1-2 Topics: Animals; Cell Nucleus; Chlorocebus aethiops; Cytoplasm; Flavonoids; Integrin alphaVbeta3; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Protein Transport; Receptors, Thyroid Hormone; Thyroxine; Vero Cells	2009
Radiosensitization of GL261 glioma cells by tetraiodothyroacetic acid (tetrac). Cell cycle (Georgetown, Tex.), 2009, Aug-15, Volume: 8, Issue:16 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glioma; Mice; Radiation Tolerance; Thyroxine; X-Rays	2009
Modification of survival pathway gene expression in human breast cancer cells by tetraiodothyroacetic acid (tetrac). Cell cycle (Georgetown, Tex.), 2009, Nov-01, Volume: 8, Issue:21 Topics: Breast Neoplasms; Carrier Proteins; Caspase 2; Cell Line, Tumor; Cell Proliferation; Cysteine Endopeptidases; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Nanoparticles; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2; Thrombospondin 1; Thyroxine; Vascular Endothelial Growth Factor A; X-Linked Inhibitor of Apoptosis Protein	2009
Tetraidothyroacetic acid (tetrac) and tetrac nanoparticles inhibit growth of human renal cell carcinoma xenografts. Anticancer research, 2009, Volume: 29, Issue:10 Topics: Animals; Carcinoma, Renal Cell; Cell Growth Processes; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Humans; Kidney Neoplasms; Lactic Acid; Mice; Nanoparticles; Neovascularization, Pathologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Xenograft Model Antitumor Assays	2009
Human platelet aggregation and degranulation is induced in vitro by L-thyroxine, but not by 3,5,3'-triiodo-L-thyronine or diiodothyropropionic acid (DITPA). Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:3 Topics: Acetates; Adenosine Triphosphate; Adolescent; Blood Platelets; Collagen; Cytoplasmic Granules; Diiodothyronines; Female; Humans; Imidazoles; Male; Phenols; Platelet Activation; Platelet Aggregation; Propionates; Receptors, Thyroid Hormone; Substrate Specificity; Thyroxine; Triiodothyronine; Young Adult	2010
Tetraiodothyroacetic acid (tetrac) and nanoparticulate tetrac arrest growth of medullary carcinoma of the thyroid. The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:4 Topics: Animals; Antineoplastic Agents; Body Weight; Carcinoma, Medullary; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Excipients; Female; Hemoglobins; Humans; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Thyroid Neoplasms; Thyroxine; Xenograft Model Antitumor Assays	2010
Tetraiodothyroacetic acid and tetraiodothyroacetic acid nanoparticle effectively inhibit the growth of human follicular thyroid cell carcinoma. Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:3 Topics: Adenocarcinoma, Follicular; Analysis of Variance; Animals; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Drug Delivery Systems; Humans; Mice; Mice, Nude; Nanoparticles; Thyroid Gland; Thyroxine; Xenograft Model Antitumor Assays	2010
Radiosensitization and production of DNA double-strand breaks in U87MG brain tumor cells induced by tetraiodothyroacetic acid (tetrac). Cell cycle (Georgetown, Tex.), 2011, Jan-15, Volume: 10, Issue:2 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Comet Assay; DNA Breaks, Double-Stranded; DNA Repair; Humans; Mice; Radiation-Sensitizing Agents; Radiation, Ionizing; Thyroxine	2011
Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system. PLoS computational biology, 2011, Feb-03, Volume: 7, Issue:2 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cetuximab; Colonic Neoplasms; Computational Biology; Drug Therapy, Combination; Female; Humans; Models, Biological; Monte Carlo Method; Nanoparticles; Resveratrol; Stilbenes; Thyroxine	2011
Active metabolism of thyroid hormone during metamorphosis of amphioxus. Integrative and comparative biology, 2010, Volume: 50, Issue:1 Topics: Animals; Antithyroid Agents; Chordata, Nonvertebrate; Chromatography, High Pressure Liquid; Gene Expression Regulation, Developmental; Larva; Metabolome; Metamorphosis, Biological; Propylthiouracil; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine	2010
A nonselenoprotein from amphioxus deiodinates triac but not T3: is triac the primordial bioactive thyroid hormone? Endocrinology, 2011, Volume: 152, Issue:8 Topics: Amino Acid Sequence; Animals; Base Sequence; Chordata, Nonvertebrate; Dithiothreitol; Iodide Peroxidase; Molecular Sequence Data; Thyroxine; Triiodothyronine	2011
Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts. Lung cancer (Amsterdam, Netherlands), 2012, Volume: 76, Issue:1 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Female; Humans; Injections, Intraperitoneal; Integrin alphaVbeta3; Lung Neoplasms; Mice; Mice, Nude; Nanoparticles; Thyroid Hormones; Thyroxine; Xenograft Model Antitumor Assays	2012
Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac). Experimental eye research, 2012, Volume: 94, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Erythropoietin; Humans; Integrin alphaVbeta3; Intravitreal Injections; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxygen; Phosphorylation; Retinal Neovascularization; Thyroxine; Vascular Endothelial Growth Factor A	2012
Crosstalk between integrin αvβ3 and estrogen receptor-α is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. PloS one, 2011, Volume: 6, Issue:11 Topics: Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Fulvestrant; Humans; Integrin alphaVbeta3; Lung Neoplasms; Phosphorylation; Proliferating Cell Nuclear Antigen; Protein Transport; Signal Transduction; Thyroid Hormones; Thyroxine	2011
Tetraiodothyroacetic acid-tagged liposomes for enhanced delivery of anticancer drug to tumor tissue via integrin receptor. Journal of controlled release : official journal of the Controlled Release Society, 2012, Dec-10, Volume: 164, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Liposomes; Mice; Mice, Nude; Neoplasms; Phospholipid Ethers; Thyroxine	2012
Modulation of diazepam-insensitive GABA(A) receptors by micromolar concentrations of thyroxine and related compounds in vitro. Brain research, 2013, Jan-15, Volume: 1490 Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Brain; Central Nervous System Depressants; Diazepam; Electrophysiological Phenomena; Ethanol; GABA Modulators; Isoxazoles; Male; Membranes; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Thyroid Hormones; Thyroxine	2013
Integrin participates in the effect of thyroxine on plasma membrane in immature rat testis. Biochimica et biophysica acta, 2013, Volume: 1830, Issue:3 Topics: Amino Acids; Aminoisobutyric Acids; Animals; Animals, Newborn; Biological Transport; Calcium; Carbon Radioisotopes; Cell Membrane; Chloride Channels; Cytoskeleton; Gene Expression Regulation; Integrin alphaVbeta3; Male; Oligopeptides; Rats; Rats, Wistar; Receptors, Cell Surface; Sertoli Cells; Signal Transduction; Spermatogenesis; Thymidine; Thyroxine	2013
Tetrac can replace thyroid hormone during brain development in mouse mutants deficient in the thyroid hormone transporter mct8. Endocrinology, 2013, Volume: 154, Issue:2 Topics: Animals; Brain; Chlorocebus aethiops; COS Cells; Membrane Transport Proteins; Mice; Mice, Knockout; Monocarboxylic Acid Transporters; Symporters; Thyroxine	2013
Tetraiodothyroacetic acid-conjugated PLGA nanoparticles: a nanomedicine approach to treat drug-resistant breast cancer. Nanomedicine (London, England), 2013, Volume: 8, Issue:12 Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine	2013
Response of human pancreatic cancer cell xenografts to tetraiodothyroacetic acid nanoparticles. Hormones & cancer, 2013, Volume: 4, Issue:3 Topics: Animals; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Pancreatic Neoplasms; Thyroxine; Transplantation, Heterologous	2013
64Cu-Labeled tetraiodothyroacetic acid-conjugated liposomes for PET imaging of tumor angiogenesis. Nuclear medicine and biology, 2013, Volume: 40, Issue:8 Topics: Animals; Cattle; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Drug Stability; Glioblastoma; Humans; Liposomes; Male; Mice; Neovascularization, Pathologic; Positron-Emission Tomography; Thyroxine	2013
Thyroid hormones differentially regulate phosphorylation of ERK and Akt via integrin αvβ3 receptor in undifferentiated and differentiated PC-12 cells. Cell biochemistry and function, 2014, Volume: 32, Issue:3 Topics: Animals; Cell Differentiation; Extracellular Signal-Regulated MAP Kinases; Forkhead Transcription Factors; Integrin alphaVbeta3; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Thyroxine; Triiodothyronine	2014
Integrin αvβ3 and thyroid hormones promote expansion of progenitors in embryonic neocortex. Development (Cambridge, England), 2014, Volume: 141, Issue:4 Topics: Animals; Extracellular Matrix; Flow Cytometry; Fluorescence; Immunohistochemistry; Integrin alphaVbeta3; Mice; Mice, Inbred C57BL; Neocortex; Neural Stem Cells; Neurogenesis; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; T-Box Domain Proteins; Thyroid Hormones; Thyroxine	2014
Thyroid hormone induced angiogenesis through the integrin αvβ3/protein kinase D/histone deacetylase 5 signaling pathway. Journal of molecular endocrinology, 2014, Volume: 52, Issue:3 Topics: Active Transport, Cell Nucleus; Cell Movement; Cells, Cultured; Endothelium, Vascular; Fibroblast Growth Factor 2; Histone Deacetylases; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Neovascularization, Physiologic; Phosphorylation; Protein Kinase C; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thyroxine; Wound Healing	2014
Effect of thyroid hormone-nitric oxide interaction on tumor growth, angiogenesis, and aminopeptidase activity in mice. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:6 Topics: Aminopeptidases; Animals; Carcinoma, Lewis Lung; Cell Proliferation; Guanidines; Hemoglobins; Male; Mice; Mice, Inbred CBA; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Thyroid Hormones; Thyroxine	2014
The pro-oxidant buthionine sulfoximine (BSO) reduces tumor growth of implanted Lewis lung carcinoma in mice associated with increased protein carbonyl, tubulin abundance, and aminopeptidase activity. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:8 Topics: Aminopeptidases; Animals; Buthionine Sulfoximine; Carcinoma, Lewis Lung; Cells, Cultured; Male; Mice; Mice, Inbred CBA; Oxidative Stress; Protein Carbonylation; Thyroxine; Tubulin	2014
Thyroid hormone regulates adhesion, migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells. Oncotarget, 2014, Aug-15, Volume: 5, Issue:15 Topics: Bortezomib; Cell Adhesion; Cell Movement; Cell Proliferation; Humans; Matrix Metalloproteinase 9; Multiple Myeloma; Receptors, Vitronectin; Thyroxine; Triiodothyronine	2014
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3. Endocrine-related cancer, 2015, Volume: 22, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Cell Movement; Culture Media, Conditioned; Heterografts; Humans; Hyperthyroidism; Hypothyroidism; Integrin alphaVbeta3; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mesenchymal Stem Cells; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Neovascularization, Pathologic; Specific Pathogen-Free Organisms; Spheroids, Cellular; Stromal Cells; Thyroxine; Triiodothyronine; Tumor Microenvironment; Xenograft Model Antitumor Assays	2015
Surface plasmon resonance assay of inhibition by pharmaceuticals for thyroxine hormone binging to transport proteins. Analytical biochemistry, 2016, Jan-01, Volume: 492 Topics: Binding, Competitive; Diclofenac; Inhibitory Concentration 50; Pharmaceutical Preparations; Prealbumin; Protein Binding; Surface Plasmon Resonance; Thyroxine; Thyroxine-Binding Globulin	2016
The combination of tetraiodothyroacetic acid and cetuximab inhibits cell proliferation in colorectal cancers with different K-ras status. Steroids, 2016, Volume: 111 Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cetuximab; Colorectal Neoplasms; Cyclin D1; Gene Expression Regulation, Neoplastic; Genes, myc; HCT116 Cells; HT29 Cells; Humans; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal, 18S; Thyroid Hormones; Thyroxine	2016
Synergistic active targeting of dually integrin αvβ3/CD44-targeted nanoparticles to B16F10 tumors located at different sites of mouse bodies. Journal of controlled release : official journal of the Controlled Release Society, 2016, 08-10, Volume: 235 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Docetaxel; Drug Liberation; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Integrin alphaVbeta3; MCF-7 Cells; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Taxoids; Thyroxine; Tumor Burden; Xenograft Model Antitumor Assays	2016
Synthesis of MR-49, a deiodinated analog of tetraiodothyroacetic acid (tetrac), as a novel pro-angiogenesis modulator. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Acetates; Angiogenesis Modulating Agents; Animals; Cell Line, Tumor; Hemoglobins; Iodine; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Phenols; Thyroxine	2016
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway. Experimental cell research, 2016, 10-01, Volume: 347, Issue:2 Topics: Anoikis; Apoptosis; Cell Line, Tumor; Cell Movement; Gene Silencing; Humans; Male; MAP Kinase Signaling System; Neoplasm Metastasis; Neoplasm Proteins; Prealbumin; Prostatic Neoplasms; Signal Transduction; Thyroxine	2016
Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy. The Journal of clinical endocrinology and metabolism, 2017, 03-01, Volume: 102, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Autoradiography; Case-Control Studies; Cells, Cultured; Chromatography, Liquid; Ependymoglial Cells; Female; Fibroblasts; Flow Cytometry; Glucuronosyltransferase; Graves Disease; Graves Ophthalmopathy; HeLa Cells; Humans; Hyaluronan Synthases; Hyaluronic Acid; Immunoassay; Immunoglobulins, Thyroid-Stimulating; Interleukin-6; Male; Middle Aged; Orbit; Prostaglandin-Endoperoxide Synthases; Real-Time Polymerase Chain Reaction; Receptors, Thyrotropin; Retinal Pigment Epithelium; Sex Factors; Tandem Mass Spectrometry; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult	2017
The effects of intra-hippocampal L-thyroxine infusion on long-term potentiation and long-term depression: A possible role for the αvβ3 integrin receptor. Journal of neuroscience research, 2017, Volume: 95, Issue:8 Topics: Analysis of Variance; Animals; Biophysics; Electric Stimulation; Hippocampus; Integrin alpha3beta1; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Rats; Rats, Wistar; Thyroxine	2017
In vitro effects of tetraiodothyroacetic acid combined with X-irradiation on basal cell carcinoma cells. Cell cycle (Georgetown, Tex.), 2017, Feb-16, Volume: 16, Issue:4 Topics: Carcinoma, Basal Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Breaks, Double-Stranded; DNA Repair; Dose-Response Relationship, Radiation; Female; Histones; Humans; Radiation Injuries; Thyroxine; Tumor Stem Cell Assay; X-Rays	2017
Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac. International journal of nanomedicine, 2017, Volume: 12 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; Dynamic Light Scattering; Female; Humans; Lactic Acid; Mice, Nude; Nanoparticles; Paclitaxel; Pancreatic Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Xenograft Model Antitumor Assays	2017
Nanoparticulate Tetrac Inhibits Growth and Vascularity of Glioblastoma Xenografts. Hormones & cancer, 2017, Volume: 8, Issue:3 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Hypothyroidism; Integrin alphaVbeta3; Mice; Nanoparticles; Neovascularization, Pathologic; Receptors, Cell Surface; Thyroxine; Xenograft Model Antitumor Assays	2017
Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo. International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1 Topics: Adenocarcinoma; Animals; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Drug Delivery Systems; Female; HT29 Cells; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Thyroxine	2017
Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer. Endocrine-related cancer, 2018, Volume: 25, Issue:3 Topics: Animals; Antineoplastic Agents; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; HMGA2 Protein; Humans; Mice, Nude; Resveratrol; Thyroxine	2018
Simultaneous targeting therapy for lung metastasis and breast tumor by blocking the NF-κB signaling pathway using Celastrol-loaded micelles. Drug delivery, 2018, Volume: 25, Issue:1 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Integrin alphaVbeta3; Lung Neoplasms; Mice; Mice, Inbred BALB C; Micelles; Neoplasm Metastasis; NF-kappa B; Pentacyclic Triterpenes; Signal Transduction; Thyroxine; Triterpenes	2018
Synthesis of new analogs of tetraiodothyroacetic acid (tetrac) as novel angiogenesis inhibitors for treatment of cancer. Bioorganic & medicinal chemistry letters, 2018, 04-15, Volume: 28, Issue:7 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred C57BL; Molecular Structure; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Structure-Activity Relationship; Thyroxine	2018
Activation of tumor cell integrin αvβ3 by radiation and reversal of activation by chemically modified tetraiodothyroacetic acid (tetrac). Endocrine research, 2018, Volume: 43, Issue:4 Topics: Animals; Chickens; Chorioallantoic Membrane; Humans; Integrin alphaVbeta3; Male; PC-3 Cells; Prostate; Thyroxine	2018
Tetrac-decorated chitosan-coated PLGA nanoparticles as a new platform for targeted delivery of SN38. Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2 Topics: Animals; Antineoplastic Agents; Biological Transport; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Female; Humans; Integrin alphaVbeta3; Mice; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Xenograft Model Antitumor Assays	2018
Tetraiodothyroacetic acid (tetrac), integrin αvβ3 and disabling of immune checkpoint defense. Future medicinal chemistry, 2018, 07-01, Volume: 10, Issue:14 Topics: B7-H1 Antigen; CTLA-4 Antigen; Humans; Integrin alphaVbeta3; Neoplasms; Thyroxine	2018
Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 120 Topics: Antineoplastic Agents; B7-H1 Antigen; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Gene Expression; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Mouth Neoplasms; Nanoparticles; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; RNA, Messenger; Thyroxine	2018
Letter to the Editor: "Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy". The Journal of clinical endocrinology and metabolism, 2019, 04-01, Volume: 104, Issue:4 Topics: Graves Disease; Graves Ophthalmopathy; Humans; Thyroxine	2019
Response to Letter to the Editor: "Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy". The Journal of clinical endocrinology and metabolism, 2019, 04-01, Volume: 104, Issue:4 Topics: Graves Disease; Graves Ophthalmopathy; Humans; Thyroxine	2019
Synthesis and characterization of Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1 Topics: Animals; Brain Neoplasms; Carbocyanines; Cells, Cultured; Copper Radioisotopes; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Neovascularization, Pathologic; Positron-Emission Tomography; Thyroxine	2020
Triiodothyronine activated extranuclear pathways upregulate adiponectin and leptin in murine adipocytes. Molecular and cellular endocrinology, 2020, 03-01, Volume: 503 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Cell Differentiation; Cytoplasm; Gene Expression; Leptin; Mice; Signal Transduction; Thyroxine; Triiodothyronine; Up-Regulation	2020
Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin α Chemosphere, 2020, Volume: 249 Topics: Binding, Competitive; Biological Assay; Dibutyl Phthalate; Esters; Integrin alphaVbeta3; Phthalic Acids; Receptors, Thyroid Hormone; Thyroid Gland; Thyroxine	2020
Combined Treatment of Heteronemin and Tetrac Induces Antiproliferation in Oral Cancer Cells. Marine drugs, 2020, Jul-02, Volume: 18, Issue:7 Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gingival Neoplasms; Humans; Terpenes; Thyroxine	2020
Nano Diaminopropane tetrac and integrin αvβ3 expression in different cancer types: Anti-cancer efficacy and Safety. Cancer treatment and research communications, 2021, Volume: 28 Topics: Animals; Antineoplastic Agents; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Male; Mice, Nude; Nanoparticles; Neoplasms; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Treatment Outcome	2021
Nano-Targeting of Thyrointegrin αvβ3 Receptor in Solid Tumors and Impact on Radiosensitization. Radiation research, 2021, 10-01, Volume: 196, Issue:4 Topics: Animals; Cell Line, Tumor; Mice; Polyglactin 910; Thyroxine; Xenograft Model Antitumor Assays	2021
Heteronemin and tetrac derivatives suppress non-small cell lung cancer growth via ERK1/2 inhibition. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 161 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Terpenes; Thyroxine	2022
Frontiers in endocrinology, 2022, Volume: 13 Topics: Heterografts; Humans; Integrin alphaVbeta3; Neoplasms; Phagocytosis; Thyroid Hormones; Thyroxine	2022