Page last updated: 2024-08-16

tetrahydropalmatine and stepholidine

tetrahydropalmatine has been researched along with stepholidine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19904 (20.00)18.7374
1990's12 (60.00)18.2507
2000's0 (0.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Chen, K; Gao, B; Guo, L; Jiang, H; Li, Z; Liu, H; Qian, W; Sun, H; Yang, H; Zhen, X; Zhou, S; Zhou, Y; Zhu, L1
Chen, LJ; Guo, X; Jin, GZ; Wang, QM1
Huang, KX; Jin, GZ1
Li, DX; Wang, W; Xuan, B1
Gonon, FG; Huang, KX; Jin, GZ; Sun, BC1
Cao, XD; Jiang, JW; Wu, G; Wu, GC1
Chen, Y; Han, YR; Jin, GZ; Xu, SX; Yu, LP1
Jin, GZ; Shi, WX; Wang, XL1
Jin, GZ2
Chen, Y; Jin, GZ; Lin, GD; Xuan, JC1
Li, DX; Xuan, B; Zhou, J1
Li, XT; Wang, JX; Wang, YL; Yang, SJ1
Jin, GZ; Wu, JH1
Han, QD; Jin, GZ; Lu, ZZ; Wei, X1
Hu, JY; Jin, GZ1
Duan, G; Guo, J; Huang, J1
Chen, L; Ge, HX; Kou, JP; Yu, BY; Zhang, J1
Chen, Y; Guo, D; Jiang, H; Li, H; Li, J; Lin, H; Liu, H; Shan, L; Shoichet, BK; Sun, H; Xie, X; Zhang, D; Zhang, W; Zhao, F; Zhou, Y1
Ahire, V; Allen, TD; Li, H; Li, J; Nimishetti, N; Shi, Q; Yan, Z; Yang, D; Zhang, J; Zhang, S1

Reviews

1 review(s) available for tetrahydropalmatine and stepholidine

ArticleYear
[Progress in studies of the pharmacology of l-tetrahydropalmatine and l-stepholidine].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1987, Volume: 22, Issue:6

    Topics: Alkaloids; Antipsychotic Agents; Berberine; Berberine Alkaloids; Receptors, Dopamine

1987

Other Studies

19 other study(ies) available for tetrahydropalmatine and stepholidine

ArticleYear
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile.
    Bioorganic & medicinal chemistry, 2013, Feb-15, Volume: 21, Issue:4

    Topics: Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; CHO Cells; Cricetinae; Cricetulus; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Microwaves; Motor Activity; Protein Binding; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship

2013
[Feed-back regulation of presynaptic D2 receptors blockaded by l-stepholidine and l-tetrahydropalmatine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Alkaloids; Animals; Apomorphine; Berberine; Berberine Alkaloids; Corpus Striatum; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Levodopa; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism

1992
The antagonistic effects of tetrahydroprotoberberines on dopamine receptors: electrophysiological studies.
    Science in China. Series B, Chemistry, life sciences & earth sciences, 1992, Volume: 35, Issue:6

    Topics: Alkaloids; Animals; Apomorphine; Berberine; Berberine Alkaloids; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra

1992
[Protective effects of tetrahydroprotoberberines on experimental myocardial infarction in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:2

    Topics: Alkaloids; Animals; Aspartate Aminotransferases; Berberine; Berberine Alkaloids; Creatine Kinase; Female; Hemodynamics; Male; Myocardial Infarction; Rats; Rats, Inbred Strains

1992
[Effects of tetrahydroprotoberberines on dopamine release and 3,4-dihydroxyphenylacetic acid level in corpus striatum measured by in vivo voltammetry].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Animals; Berberine; Berberine Alkaloids; Calcium Channel Blockers; Caudate Nucleus; Corpus Striatum; Dopamine; Male; Microelectrodes; Polarography; Rats; Stereoisomerism

1991
[Potentiation of electroacupuncture analgesia by l-tetrahydropalmatine and its analogues in rabbits].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:2

    Topics: Acupuncture Analgesia; Alkaloids; Animals; Berberine; Berberine Alkaloids; Electroacupuncture; Female; Male; Pain; Rabbits; Sensory Thresholds

1990
Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2

    Topics: Adenylyl Cyclases; Alkaloids; Animals; Berberine; Berberine Alkaloids; Brain; Cattle; Corpus Striatum; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereoisomerism

1989
Tetrahydroprotoberberine--a new chemical type of antagonist of dopamine receptors.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1986, Volume: 29, Issue:5

    Topics: Alkaloids; Animals; Antipsychotic Agents; Berberine; Berberine Alkaloids; Corpus Striatum; Haloperidol; Rats; Receptors, Dopamine; Scopolamine; Substantia Nigra

1986
[Relevance of stereo and quantum chemistry of four tetrahydroprotoberberines to their effects on dopamine receptors].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:3

    Topics: Alkaloids; Animals; Berberine; Berberine Alkaloids; Cattle; Molecular Conformation; Quantum Theory; Rats; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship

1988
[Relation between cerebral dopaminergic system and pharmacological action of 1-tetrahydroprotoberbines].
    Sheng li ke xue jin zhan [Progress in physiology], 1993, Volume: 24, Issue:2

    Topics: Animals; Berberine; Berberine Alkaloids; Dopamine Antagonists; Drugs, Chinese Herbal; Stereoisomerism; Structure-Activity Relationship

1993
Effects of tetrahydroberberine on ischemic and reperfused myocardium in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Berberine; Berberine Alkaloids; In Vitro Techniques; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Verapamil; Xanthine Oxidase

1993
[Effects of tetrahydroprotoberberines on cytosolic free calcium in cultured rat single myocardial cells].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:8

    Topics: Animals; Animals, Newborn; Berberine; Berberine Alkaloids; Biological Transport, Active; Calcium; Calcium Channel Blockers; Cells, Cultured; Myocardium; Rats; Rats, Sprague-Dawley; Verapamil

1995
[Effects of (-) SPD and (-) THP on the firing of noradrenergic neurons in locus coeruleus].
    Sheng li xue bao : [Acta physiologica Sinica], 1995, Volume: 47, Issue:6

    Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Animals; Berberine; Berberine Alkaloids; Electrophysiology; Locus Coeruleus; Male; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha

1995
[Antagonistic effect of tetrahydroproberberine homologues on alpha 1-adrenoceptor].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:9

    Topics: Adrenergic alpha-Antagonists; Animals; Berberine; Berberine Alkaloids; Binding, Competitive; Male; Rats; Receptors, Adrenergic, alpha-1; Vasoconstriction

1996
Effect of tetrahydropalmatine analogs on Fos expression induced by formalin-pain.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:3

    Topics: Analgesics, Non-Narcotic; Animals; Berberine; Berberine Alkaloids; Brain; Dopamine Agonists; Dopamine Antagonists; Formaldehyde; Male; Pain; Proto-Oncogene Proteins c-fos; Quinpirole; Rats; Rats, Sprague-Dawley; Spinal Cord; Spiperone

1999
[Determination of 7 bio-active alkaloids in Stephania plants by RP-HPLC].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:7

    Topics: Alkaloids; Aporphines; Benzylisoquinolines; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Morphinans; Species Specificity; Stephania

1998
Chemical and microbial semi-synthesis of tetrahydroprotoberberines as inhibitors on tissue factor procoagulant activity.
    Bioorganic & medicinal chemistry, 2013, Jan-01, Volume: 21, Issue:1

    Topics: Berberine Alkaloids; Cell Line; Gliocladium; Glycosylation; Humans; Streptomyces griseus; Structure-Activity Relationship; Thromboplastin

2013
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α
    Journal of medicinal chemistry, 2016, Oct-27, Volume: 59, Issue:20

    Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Berberine Alkaloids; Dose-Response Relationship, Drug; Drug Design; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Male; Mice; Mice, Inbred Strains; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship; Tumor Cells, Cultured

2016
The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects.
    Journal of natural products, 2021, 08-27, Volume: 84, Issue:8

    Topics: Aurora Kinase A; Aurora Kinase B; Berberine Alkaloids; Cell Line; China; Corydalis; Cytokinesis; Enzyme Inhibitors; Humans; Mitosis; Molecular Structure; Phytochemicals; Rhizome

2021