Compounds > tetrahydrofuran
Page last updated: 2024-08-18

tetrahydrofuran and oxazoles

tetrahydrofuran has been researched along with oxazoles in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Brodney, MA; Coffman, KJ; Lee, C; Miller, E; Obach, RS; Rapp, T; Ryder, TF; Sawant-Basak, A; Tseng, E; Vanase-Frawley, MA; Walker, GS; Wong, JW1
Duvvuri, S; Kadar, EP; Kimoto, E; Lin, J; Nicholas, T; Obach, RS; Sawant-Basak, A; Tremaine, LM1
Campos Bernardes, LS; da Rosa, R; Dambrós, BP; Grand, L; Höehr de Moraes, M; Jacolot, M; Popowycz, F; Schenkel, EP; Steindel, M1

Other Studies

3 other study(ies) available for tetrahydrofuran and oxazoles

ArticleYear
Metabolism of a serotonin-4 receptor partial agonist 4-{4-[4-tetrahydrofuran-3-yloxy)-benzo[d]isoxazol-3-yloxymethyl]-piperidin-1-ylmethyl}-tetrahydropyran-4-ol (TBPT): identification of an unusual pharmacologically active cyclized oxazolidine metabolite
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:9

    Topics: Animals; Blood Proteins; Brain; Cyclization; Dealkylation; Dogs; Female; Furans; Hepatocytes; Humans; Hydroxylation; Male; Microsomes, Liver; Oxazoles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists

2013
Estimation of Circulating Drug Metabolite Exposure in Human Using In Vitro Data and Physiologically Based Pharmacokinetic Modeling: Example of a High Metabolite/Parent Drug Ratio.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:2

    Topics: Adult; Cyclization; Dealkylation; Female; Furans; Hepatocytes; Humans; Inactivation, Metabolic; Kinetics; Male; Middle Aged; Models, Biological; Oxazoles; Serotonin Receptor Agonists; Young Adult

2018
Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure-activity relationship, toxicity, and mechanism of action.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Alkaloids; Biological Products; Dose-Response Relationship, Drug; Drug Design; Furans; Humans; Lignans; Molecular Structure; Oxazoles; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2022