Page last updated: 2024-08-18

tetrahydrofuran and lignans

tetrahydrofuran has been researched along with lignans in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's1 (2.22)18.2507
2000's16 (35.56)29.6817
2010's22 (48.89)24.3611
2020's5 (11.11)2.80

Authors

AuthorsStudies
Biftu, T; Doebber, T; Gamble, NF; Hwang, SB; Shen, TY; Snyder, J; Springer, JP; Stevenson, R1
Chen, CC; Chen, HY; Kuo, YH; Lin, YL; Ou, JC; Shiao, MS1
Eich, E; Jakupovic, J; Jenett-Siems, K; Siems, K; Tofern, B1
Kato, MJ; Latorre, LR; Martins, RC; Sartorelli, P1
Heilmann, J; Schmidt, TJ1
Kinoshita, Y; Yamauchi, S1
Albuquerque, S; Bastos, JK; da Silva Filho, AA; Eberlin, MN; Silva, ML; Tomazela, DM1
Akiyama, K; Kashiwagi, T; Kishida, T; Okazaki, M; Sugahara, T; Yamauchi, S1
Ando, M; Hasegawa, T; Kakuta, S; Kataoka, T; Kiuchi, M; Li, N; Ogura, H; Oka, S; Sakai, J; Tang, W; Tomida, A; Tsuruo, T; Wu, JL1
Li, N; Wang, MW; Wang, YH; Zhang, GL; Zhang, Z; Zheng, YT1
Akiyama, K; Kishida, T; Maruyama, M; Nakato, T; Sugahara, T; Tsuchiya, M; Yamauchi, S1
Nakato, T; Yamauchi, S1
Baldoqui, DC; Bolzani, Vda S; Cicarelli, RM; Felippe, LG; Furlan, M; Guimarães, EF; Kato, MJ1
Cui, J; Jang, MH; Piao, X; Piao, XL1
Li, N; Lin, LL; Wang, MW; Zhang, GL1
Gao, XM; Huang, SX; Lei, C; Li, LM; Pu, JX; Sun, HD; Wang, RR; Xiao, WL; Yang, LB; Zhao, Y; Zheng, YT1
Di, Y; Hao, X; He, H; Li, L; Ma, Y; Tian, J; Yang, X1
Dewhirst, MW; Hong, J; Hu, X; Kasper, AC; Kim, H; Moon, EJ; Park, Y; Wooten, CM; Yang, W1
Chen, H; Hua, HM; Li, ZL; Liu, XQ; Sun, YJ; Zhou, W1
Ding, L; He, D; Lei, X; Xiao, H; Xu, H; Zhou, Y1
Chen, JC; Duan, HQ; Fang, JB; Gao, SS; Jiang, HL; Qing, GL; Wang, XG; Zhang, PP; Zhang, TT1
Huang, J; Li, GY; Lin, RC; Wang, HQ; Wang, JH; Zhang, C1
Cheng, Z; Qin, Y; Yin, C1
Pohjoispää, M; Wähälä, K1
Lin, LC; Shen, CC; Tsai, TH; Tsai, WJ1
Li, H; Ma, H; She, X; Xie, X; Zhang, Y; Zhao, C; Zhao, G1
Jan, KC; Liu, TC; Yang, BB1
Albertson, AK; Lumb, JP1
Esumi, T; Fukuyama, Y; Harada, K; Hioki, H; Horiuchi, H; Ishii, A; Kubo, M1
Bang, J; Kwon, J; Lee, E; Yu, CM1
Hu, J; Li, H; Mao, X; Shi, XD; Song, Y1
Bai, XC; Cao, XL; Yun, Y; Zhang, QL1
Arruda, CC; Baroni, AC; Bosquiroli, LS; Carvalho, DB; Cassamale, TB; Costa, EC; Kadri, MC; Matos, MF; Ojeda, M; Ximenes, TV1
Cheng, YC; Su, GY; Wang, KW; Wang, XY; Wu, B1
Kaiho, A; Nishimura, H; Okada, H; Saito, K; Sakai, R; Watanabe, T1
Muhit, MA; Noguchi, H; Umehara, K1
Císařová, I; Jagtap, PR; Jahn, U1
Abe, I; Asakawa, Y; Imagawa, H; Ito, T; Morita, H; Ngwe, H; Okamoto, Y; Tanaka, M; Win, NN; Wong, CP; Woo, SY1
Francis, SK; James, B; Nair, MS; Varughese, S1
Arruda, CCP; Barbosa, NV; Baroni, ACM; Carvalho, DB; das Neves, AR; Honorato, AM; Kadri, MCT; Kato, MJ; Moslaves, IS; Trefzger, OS; Yoshida, NC1
Wang, D; Yang, CR; Yang, Z; Zhang, XR; Zhang, YJ; Zhu, HT1
Ge, Y; Hong, J; Kim, JH; Kwak, SH; Kwon, DY; Lee, H; Lee, HE; Lee, YM; Min, SM; Stephenson, TN1
Akkarawongsapat, R; Chairoungdua, A; Chaturonrutsamee, S; Hongthong, S; Hosen, A; Kuhakarn, C; Limthongkul, J; Napaswad, C; Nuntasaen, N; Reutrakul, V; Sukbangnop, W; Suksen, K; Thanasansurapong, S; Tuchinda, P1
Campos Bernardes, LS; da Rosa, R; Dambrós, BP; Grand, L; Höehr de Moraes, M; Jacolot, M; Popowycz, F; Schenkel, EP; Steindel, M1
Nishiwaki, H; Tanaka, M; Yamauchi, S1

Reviews

2 review(s) available for tetrahydrofuran and lignans

ArticleYear
[Recent progresses in studies on bioactive lignans from plants].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2007, Volume: 32, Issue:20

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antiviral Agents; Cyclooctanes; Furans; Humans; Lignans; Molecular Structure; Plants, Medicinal

2007
Synthesis of 3,4-dibenzyltetrahydrofuran lignans (9,9'-epoxylignanes).
    Molecules (Basel, Switzerland), 2013, Oct-24, Volume: 18, Issue:11

    Topics: Furans; Lignans; Molecular Structure; Stereoisomerism

2013

Other Studies

43 other study(ies) available for tetrahydrofuran and lignans

ArticleYear
Conformation and activity of tetrahydrofuran lignans and analogues as specific platelet activating factor antagonists.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: Animals; Furans; Lignans; Molecular Conformation; Plant Extracts; Platelet Activating Factor; Rabbits; Structure-Activity Relationship

1986
Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco.
    Planta medica, 1999, Volume: 65, Issue:8

    Topics: Furans; Humans; Lignans; Lipoproteins, LDL; Male; Oxidation-Reduction; Plants, Medicinal

1999
Bonaspectins and neobonaspectins, first sesquilignans and sesquineolignans from a convolvulaceous species.
    Phytochemistry, 2000, Volume: 53, Issue:1

    Topics: Africa; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Furans; Lignans; Madagascar; Magnetic Resonance Spectroscopy; Plants, Medicinal

2000
Phenylpropanoids and tetrahydrofuran lignans from Piper solmsianum.
    Phytochemistry, 2000, Volume: 55, Issue:7

    Topics: Anthracenes; Furans; Lignans; Molecular Structure; Perylene; Phenylpropionates; Piperidines; Spectrum Analysis

2000
Tetrahydrofuran lignans from Illicium floridanum and their activity in a luminol enhanced chemiluminescence assay.
    Planta medica, 2000, Volume: 66, Issue:8

    Topics: Cell Line; Furans; Humans; Lignans; Luminescent Measurements; Luminol; Magnoliopsida; Neutrophils

2000
First stereoselective synthesis of (+)-magnostellin C, a tetrahydrofuran type of lignan bearing a chiral secondary benzyl alcohol.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:7

    Topics: Dioxoles; Furans; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Plants; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism

2001
Tetrahydrofuran lignans from Nectandra megapotamica with trypanocidal activity.
    Journal of natural products, 2004, Volume: 67, Issue:1

    Topics: Animals; Brazil; Furans; Inhibitory Concentration 50; Lauraceae; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2004
First enantioselective synthesis of (-)- and (+)-virgatusin, tetra-substituted tetrahydrofuran lignan.
    Organic & biomolecular chemistry, 2005, May-07, Volume: 3, Issue:9

    Topics: Furans; Lignans; Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Stereoisomerism

2005
Bioactive tetrahydrofuran lignans from Peperomia dindygulensis.
    Journal of natural products, 2005, Volume: 68, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Furans; Humans; Intercellular Adhesion Molecule-1; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peperomia; Plants, Medicinal; Tumor Cells, Cultured

2005
Bioactive lignans from Peperomia heyneana.
    Journal of natural products, 2007, Volume: 70, Issue:4

    Topics: Anti-HIV Agents; Drugs, Chinese Herbal; Furans; HIV-1; Humans; Lignans; Molecular Structure; Peperomia; Plants, Medicinal; T-Lymphocytes

2007
Use of the benzyl mesylate for the synthesis of tetrahydrofuran lignan: syntheses of 7,8-trans, 7',8'-trans, 7,7'-cis, and 8,8'-cis-virgatusin stereoisomers.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:9

    Topics: Benzyl Compounds; Furans; Lignans; Mesylates; Molecular Structure; Stereoisomerism

2007
Enantioselective synthesis of the tetrahydrofuran lignans (-)- and (+)-magnolone.
    Journal of natural products, 2007, Volume: 70, Issue:10

    Topics: Furans; Lignans; Magnolia; Molecular Structure; Stereoisomerism

2007
Trypanocidal tetrahydrofuran lignans from Peperomia blanda.
    Phytochemistry, 2008, Volume: 69, Issue:2

    Topics: Animals; Furans; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Peperomia; Trypanocidal Agents; Trypanosoma cruzi

2008
Lignans from the fruits of Forsythia suspensa.
    Bioorganic & medicinal chemistry letters, 2008, Mar-15, Volume: 18, Issue:6

    Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Forsythia; Fruit; Furans; Glucosides; Lignans; LLC-PK1 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Molsidomine; Nitric Oxide Donors; Oxidative Stress; Peroxynitrous Acid; Plant Extracts; Swine

2008
Three new compounds from Kadsura longipedunculata.
    Chemical & pharmaceutical bulletin, 2008, Volume: 56, Issue:8

    Topics: Anti-HIV Agents; Drugs, Chinese Herbal; Furans; Humans; Kadsura; Lignans; Microbial Sensitivity Tests; Molecular Structure; Phytotherapy; Sesquiterpenes

2008
Antioxidant lignans from Mananthes patentiflora.
    Planta medica, 2009, Volume: 75, Issue:5

    Topics: Acanthaceae; Antioxidants; Furans; Glycosides; Lignans; Molecular Structure; Plant Components, Aerial; Plant Extracts

2009
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.
    Bioorganic & medicinal chemistry letters, 2009, Jul-15, Volume: 19, Issue:14

    Topics: Animals; Cell Line; Furans; Hypoxia-Inducible Factor 1; Lignans; Mice; Vascular Endothelial Growth Factor A

2009
Four new cytotoxic tetrahydrofuranoid lignans from Sinopodophyllum emodi.
    Planta medica, 2012, Volume: 78, Issue:5

    Topics: Berberidaceae; Cell Line, Tumor; Cell Survival; China; Furans; Humans; Lignans; Molecular Structure; Plant Roots; Rhizome

2012
Gymnothelignans A-O: conformation and absolute configuration analyses of lignans bearing tetrahydrofuran from Gymnotheca chinensis.
    The Journal of organic chemistry, 2012, Oct-05, Volume: 77, Issue:19

    Topics: Benzofurans; Biological Products; Crystallography, X-Ray; Furans; Lignans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Stereoisomerism

2012
Two new compounds from Schisandra glaucescens.
    Journal of Asian natural products research, 2013, Volume: 15, Issue:5

    Topics: Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Furans; HCT116 Cells; Humans; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Stems; Schisandra; Sesquiterpenes; Stereoisomerism

2013
A new tetrahydrofuran-type lignan with anti-inflammatory activity from Asarum heterotropoides Fr. Schmidt var. mandshuricum.
    Journal of Asian natural products research, 2014, Volume: 16, Issue:4

    Topics: Algorithms; Animals; Anti-Inflammatory Agents; Asarum; Drugs, Chinese Herbal; Furans; Lignans; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Plant Roots

2014
A new tetrahydrofuran lignan diglycoside from Viola tianshanica Maxim.
    Molecules (Basel, Switzerland), 2013, Nov-04, Volume: 18, Issue:11

    Topics: Furans; Glycosides; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Viola

2013
Lignans from the aerial parts of Saururus chinensis: isolation, structural characterization, and their effects on platelet aggregation.
    Journal of natural products, 2014, Jan-24, Volume: 77, Issue:1

    Topics: Algorithms; Animals; Furans; Inhibitory Concentration 50; Lignans; Molecular Structure; Plant Roots; Platelet Aggregation; Saururaceae; Taiwan

2014
Bioinspired total synthesis of gymnothelignan N.
    Organic letters, 2014, Sep-05, Volume: 16, Issue:17

    Topics: Aldehydes; Furans; Lignans; Molecular Structure; Saururaceae; Stereoisomerism

2014
Gene expression profiling of sesaminol triglucoside and its tetrahydrofuranoid metabolites in primary rat hepatocytes.
    International journal of food sciences and nutrition, 2014, Volume: 65, Issue:8

    Topics: 4-Butyrolactone; Animals; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; Dioxoles; Furans; Gene Expression; Gene Expression Profiling; Glucosides; Hepatocytes; Inactivation, Metabolic; Lignans; Liver; Mammals; Plant Extracts; Rats, Sprague-Dawley; Seeds; Sesamum

2014
A bio-inspired total synthesis of tetrahydrofuran lignans.
    Angewandte Chemie (International ed. in English), 2015, Feb-09, Volume: 54, Issue:7

    Topics: Biomimetics; Coumaric Acids; Furans; Lignans; Oxidation-Reduction; Phenols

2015
Systematic Asymmetric Synthesis of All Diastereomers of (-)-Talaumidin and Their Neurotrophic Activity.
    The Journal of organic chemistry, 2015, Jul-17, Volume: 80, Issue:14

    Topics: Animals; Aristolochia; Cell Differentiation; Cell Line; Furans; Lignans; Nerve Growth Factors; Neurons; PC12 Cells; Rats; Stereoisomerism

2015
Enantioselective Synthesis of a Furan Lignan (+)-Sylvone.
    The Journal of organic chemistry, 2015, Oct-16, Volume: 80, Issue:20

    Topics: Benzaldehydes; Catalysis; Furans; Heterocyclic Compounds; Lignans; Molecular Structure; Naphthalenes; Stereoisomerism

2015
Tetrahydrofuran lignans from Viburnum betulifolium.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:9

    Topics: Benzofurans; Diterpenes; Drugs, Chinese Herbal; Furans; Lignans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Viburnum

2016
[Chemical Constituents from Drypetes hainanensis Stems and Leaves].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015, Volume: 38, Issue:10

    Topics: Drugs, Chinese Herbal; Furans; Glucosides; Glycosides; Lignans; Magnoliopsida; Phenylpropionates; Phytochemicals; Plant Leaves; Plant Stems; Plants, Medicinal

2015
Antileishmanial Activity and Structure-Activity Relationship of Triazolic Compounds Derived from the Neolignans Grandisin, Veraguensin, and Machilin G.
    Molecules (Basel, Switzerland), 2016, Jun-20, Volume: 21, Issue:6

    Topics: Animals; Antiprotozoal Agents; Furans; Humans; Leishmania; Leishmaniasis; Lignans; Macrophages; Nitric Oxide; Structure-Activity Relationship

2016
An Unusual Tetrahydrofuran Lignan from the Roots of Zanthoxylum planispinum and the Potential Anti-inflammatory Effects.
    Chemistry & biodiversity, 2017, Volume: 14, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Furans; Inhibitory Concentration 50; Lignans; Mice; Nitric Oxide; Plant Extracts; Plant Roots; RAW 264.7 Cells; Zanthoxylum

2017
Characterization of the Interunit Bonds of Lignin Oligomers Released by Acid-Catalyzed Selective Solvolysis of Cryptomeria japonica and Eucalyptus globulus Woods via Thioacidolysis and 2D-NMR.
    Journal of agricultural and food chemistry, 2016, Dec-07, Volume: 64, Issue:48

    Topics: Cryptomeria; Eucalyptus; Furans; Gas Chromatography-Mass Spectrometry; Lignans; Lignin; Magnetic Resonance Spectroscopy; Molecular Structure; Wood

2016
α-Keto tetrahydrofuran lignan glucosides from the Bangladeshi medicinal plant Terminalia citrina inhibit estradiol (E2) induced proliferation in cancer cells.
    Phytochemistry, 2018, Volume: 145

    Topics: Antineoplastic Agents, Phytogenic; Bangladesh; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estradiol; Furans; Glucosides; Humans; Lignans; Molecular Structure; Plant Leaves; Plants, Medicinal; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Bioinspired total synthesis of tetrahydrofuran lignans by tandem nucleophilic addition/redox isomerization/oxidative coupling and cycloetherification reactions as key steps.
    Organic & biomolecular chemistry, 2018, 01-31, Volume: 16, Issue:5

    Topics: Aldehydes; Biomimetics; Catalysis; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Cyclization; Furans; Isomerism; Lignans; Models, Molecular; Oxidation-Reduction; Oxidative Coupling; Ruthenium

2018
Tetrahydrofuran lignans: Melanogenesis inhibitors from Premna integrifolia wood collected in Myanmar.
    Fitoterapia, 2018, Volume: 127

    Topics: Animals; Cell Line, Tumor; Furans; Lamiaceae; Lignans; Melanins; Melanoma, Experimental; Mice; Molecular Structure; Myanmar; Wood

2018
Phytochemical investigation on Myristica fragrans stem bark.
    Natural product research, 2019, Volume: 33, Issue:8

    Topics: Anisoles; Benzofurans; Dioxoles; Furans; India; Indonesia; Lignans; Molecular Structure; Myristica; Phytochemicals; Plant Bark; Spectrum Analysis; Sri Lanka

2019
Effect of isoxazole derivatives of tetrahydrofuran neolignans on intracellular amastigotes of Leishmania (Leishmania) amazonensis: A structure-activity relationship comparative study with triazole-neolignan-based compounds.
    Chemical biology & drug design, 2019, Volume: 94, Issue:6

    Topics: Animals; Antiprotozoal Agents; Drug Design; Female; Furans; Inhibitory Concentration 50; Isoxazoles; Leishmania; Life Cycle Stages; Lignans; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Nitric Oxide; Structure-Activity Relationship; Triazoles

2019
Termitomenins A-E: Five new lignans from Terminalia chebula var. tomentella (Kurz) C. B. Clarke.
    Fitoterapia, 2020, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents; China; Fruit; Furans; Lignans; Mice; Molecular Structure; Nitric Oxide; Phytochemicals; RAW 264.7 Cells; Terminalia

2020
Evaluation of Manassantin A Tetrahydrofuran Core Region Analogues and Cooperative Therapeutic Effects with EGFR Inhibition.
    Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13

    Topics: ErbB Receptors; Furans; HEK293 Cells; Humans; Lignans; Protein Kinase Inhibitors

2020
Bioactive tetrahydrofuran lignans from roots, stems, leaves and twigs of Anogeissus rivularis.
    Fitoterapia, 2021, Volume: 151

    Topics: Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Combretaceae; Furans; Humans; Lignans; Molecular Structure; Phytochemicals; Plant Leaves; Plant Roots; Plant Stems; Reverse Transcriptase Inhibitors; Thailand

2021
Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure-activity relationship, toxicity, and mechanism of action.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Alkaloids; Biological Products; Dose-Response Relationship, Drug; Drug Design; Furans; Humans; Lignans; Molecular Structure; Oxazoles; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi

2022
Syntheses of Tetrahydropyran Type 8,7'-Neolignans Using a Ring-Expansion Reaction and Tetrahydrofuran Type 8,7'-Neolignans to Discover a Novel Phytotoxic Neolignan.
    Journal of agricultural and food chemistry, 2023, Jun-14, Volume: 71, Issue:23

    Topics: Lactuca; Lignans; Lolium; Stereoisomerism

2023