tetrahydrofuran has been researched along with darunavir in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghosh, AK; Koh, Y; Kumaragurubaran, N; Mitsuya, H; Ramu Sridhar, P; Weber, IT | 1 |
| Agniswamy, J; Ghosh, AK; Louis, JM; Rao, KV; Sayer, JM; Shen, CH; Wang, YF; Weber, IT; Xu, CX | 1 |
| Agniswamy, J; Ghosh, AK; Louis, JM; Shen, CH; Weber, IT; Yashchuk, S | 1 |
| Ali, A; Henes, M; Kosovrasti, K; Kurt Yilmaz, N; Lee, SK; Lockbaum, GJ; Nalivaika, EA; Rao, DN; Rusere, LN; Schiffer, CA; Spielvogel, E; Swanstrom, R | 1 |
1 review(s) available for tetrahydrofuran and darunavir
| Article | Year |
|---|---|
Bis-tetrahydrofuran: a privileged ligand for darunavir and a new generation of hiv protease inhibitors that combat drug resistance.
Topics: Animals; Darunavir; Drug Resistance, Viral; Furans; HIV Protease Inhibitors; Humans; Ligands; Models, Molecular; Sulfonamides | 2006 |
3 other study(ies) available for tetrahydrofuran and darunavir
| Article | Year |
|---|---|
Extreme multidrug resistant HIV-1 protease with 20 mutations is resistant to novel protease inhibitors with P1'-pyrrolidinone or P2-tris-tetrahydrofuran.
Topics: Binding Sites; Calorimetry, Differential Scanning; Carbamates; Crystallization; Darunavir; Drug Resistance, Multiple; Drug Resistance, Viral; Escherichia coli; Furans; Genes, Synthetic; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Models, Molecular; Mutation; Pyrrolidinones; Structure-Activity Relationship; Sulfonamides | 2013 |
Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20.
Topics: Carbamates; Crystallography, X-Ray; Darunavir; Drug Resistance, Viral; Furans; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Models, Molecular; Mutation; Structure-Activity Relationship; Sulfonamides | 2015 |
Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere.
Topics: Crystallography, X-Ray; Darunavir; Dipeptides; Drug Design; Furans; HEK293 Cells; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Models, Molecular; Structure-Activity Relationship | 2020 |