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tetraethylammonium and 1-methyl-4-phenylpyridinium

tetraethylammonium has been researched along with 1-methyl-4-phenylpyridinium in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (37.78)18.2507
2000's19 (42.22)29.6817
2010's9 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gambaryan, S; Gorboulev, V; Gründemann, D; Koepsell, H; Veyhl, M1
Arndt, P; Busch, AE; Gorboulev, V; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Waldegger, S1
Dresser, MJ; Giacomini, KM; Gray, AT; Terashita, S; Yost, SC; Zhang, L1
Akhoundova, A; Baumann, C; Busch, AE; Gorboulev, V; Karbach, U; Koepsell, H; Lang, F; Quester, S; Ulzheimer, JC; Ulzheimer-Teuber, I1
Fei, YJ; Ganapathy, V; Kekuda, R; Leibach, FH; Prasad, PD; Wang, H; Wu, X1
Giacomini, KM; Schaner, ME; Zhang, L1
Inui, KI; Masuda, S; Okuda, M; Saito, H; Urakami, Y1
Gründemann, D; Kiefer, N; Köster, S; Liebich, G; Schömig, E1
Chen, J; Conway, SJ; Ganapathy, V; Huang, W; Leibach, FH; Prasad, PD; Rajan, DP; Seth, P; Wu, X1
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Akhoundova, A; Arndt, P; Gorboulev, V; Koepsell, H; Volk, C1
Conway, SJ; Ganapathy, V; George, RL; Huang, W; Leibach, FH; Wang, H; Wu, X1
Conway, SJ; Ganapathy, ME; Ganapathy, V; Huang, W; Kekuda, R; Leibach, FH; Wang, H; Wu, X1
Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A1
Buitelaar, M; Jonker, JW; Koepsell, H; Mol, CA; Schinkel, AH; Smit, JW; Wagenaar, E1
Akhoundova, A; Arndt, P; Bamberg, E; Budiman, T; Gorboulev, V; Koepsell, H; Koppatz, S; Nagel, G; Popp, C; Ulzheimer-Teuber, I; Volk, C1
Akazawa, M; Inui, K; Okuda, M; Saito, H; Urakami, Y1
Kakehi, M; Koyabu, N; Kuwano, M; Nakamura, T; Ohtani, H; Sawada, Y; Uchiumi, T1
Bednarczyk, D; Ekins, S; Wikel, JH; Wright, SH1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Lazaruk, KD; Wright, SH1
Dantzler, WH; Gandolfi, AJ; Groves, CE; Morales, MN; Wright, SH1
Wright, SH; Wunz, TM1
Ullrich, KJ1
Inui, K; Okuda, M; Saito, H; Urakami, Y1
Beier, DR; Green, RM; Lo, K; Sterritt, C1
Chancy, CD; Ganapathy, V; Huang, W; Kekuda, R; Rajan, PD; Smith, SB1
Calhau, C; Gründemann, D; Martel, F; Schömig, E1
Bridges, CC; Friedrich, A; Ganapathy, V; George, RL; Prasad, PD1
Brust, P; Freyer, D; Friedrich, A; Ganapathy, V; Prasad, PD1
Arioka, S; Matsumoto, T; Morimoto, R; Moriyama, Y; Omote, H; Otsuka, M1
Kang, HJ; Kim, WY; Lee, CH; Lee, SS; Shim, JC; Shin, HJ; Shin, JG; Song, IS; Zhou, HH1
Cherrington, NJ; Wright, SH; Zhang, X1
Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI1
Irokawa, M; Iwanaga, T; Koibuchi, H; Maeda, T; Nakakariya, M; Shimada, T; Tamai, I; Yabuuchi, H1
Inui, K; Katsura, T; Masuda, S; Sato, T; Tanihara, Y; Yonezawa, A1
Giacomini, KM; Ianculescu, AG; Scanlan, TS1
Duan, H; Wang, J1
Inoue, K; Ito, S; Kusuhara, H; Sugiyama, Y; Toyoshima, J; Yokochi, M; Yuasa, H1
Choi, MK; Song, IS1
Cheng, Y; Dangprapai, Y; Pelis, RM; Terpstra, J; Wright, SH; Zhang, X1
Harper, JN; Wright, SH1
Berteloot, A; Martínez-Guerrero, LJ; Morales, M; Secomb, TW; Shibayama, T; Wright, SH; Zhang, X1
Aoyagi, M; Ishizaki, S; Ishizaki, Y; Matsumoto, T; Mitoma, Y; Mochizuki, K; Nagashima, Y1

Reviews

1 review(s) available for tetraethylammonium and 1-methyl-4-phenylpyridinium

ArticleYear
Renal transporters for organic anions and organic cations. Structural requirements for substrates.
    The Journal of membrane biology, 1997, Jul-15, Volume: 158, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anions; Cations; Choline; Dicarboxylic Acids; Humans; Ion Transport; Kidney; Kinetics; Niacinamide; p-Aminohippuric Acid; Sulfates; Tetraethylammonium; Tetraethylammonium Compounds

1997

Other Studies

44 other study(ies) available for tetraethylammonium and 1-methyl-4-phenylpyridinium

ArticleYear
Drug excretion mediated by a new prototype of polyspecific transporter.
    Nature, 1994, Dec-08, Volume: 372, Issue:6506

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cations; Cells, Cultured; DNA, Complementary; Intestinal Mucosa; Kidney Tubules, Proximal; Liver; Membrane Proteins; Molecular Sequence Data; Organic Cation Transporter 1; Pharmacokinetics; Recombinant Proteins; RNA, Messenger; Xenopus

1994
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.
    The Journal of biological chemistry, 1996, Dec-20, Volume: 271, Issue:51

    Topics: Animals; Base Sequence; Biological Transport; Carrier Proteins; Cations; Choline; Electric Conductivity; Kidney; Lidocaine; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Niacinamide; Organic Cation Transporter 1; Pyridinium Compounds; Rats; Recombinant Proteins; Substrate Specificity

1996
Cloning and functional expression of a human liver organic cation transporter.
    Molecular pharmacology, 1997, Volume: 51, Issue:6

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Polymerase Chain Reaction; Rats; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Tissue Distribution; Xenopus laevis

1997
Cloning and characterization of two human polyspecific organic cation transporters.
    DNA and cell biology, 1997, Volume: 16, Issue:7

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carrier Proteins; Cations; Cell Membrane; Cloning, Molecular; Electric Conductivity; Humans; Ion Transport; Kidney Cortex; Kidney Tubules, Distal; Kinetics; Liver; Membrane Proteins; Molecular Sequence Data; Oocytes; Organ Specificity; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; RNA, Messenger; Sequence Homology, Amino Acid; Xenopus laevis

1997
Cloning and functional characterization of a potential-sensitive, polyspecific organic cation transporter (OCT3) most abundantly expressed in placenta.
    The Journal of biological chemistry, 1998, Jun-26, Volume: 273, Issue:26

    Topics: Amino Acid Sequence; Animals; Cloning, Molecular; DNA-Binding Proteins; HeLa Cells; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Octamer Transcription Factor-3; Oocytes; Placenta; Protein Conformation; Rats; Transcription Factors; Xenopus laevis

1998
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection

1998
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Base Sequence; Carrier Proteins; Cations; Cell Line; Cell Membrane; DNA Primers; Dogs; Kidney Tubules; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Tetraethylammonium

1998
Selective substrates for non-neuronal monoamine transporters.
    Molecular pharmacology, 1999, Volume: 56, Issue:1

    Topics: Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; DNA, Complementary; Guanidine; Histamine; Humans; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Neuropeptides; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Sequence Homology, Amino Acid; Vesicular Biogenic Amine Transport Proteins

1999
Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Acetylcarnitine; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Humans; In Situ Hybridization; Kidney; Membrane Proteins; Mice; Myocardium; Organ Specificity; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium

1999
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.
    Molecular pharmacology, 1999, Volume: 56, Issue:6

    Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Ion Transport; Membrane Proteins; Mutagenesis, Site-Directed; Organic Cation Transporter 1; Quaternary Ammonium Compounds; Tetraethylammonium; Xenopus laevis

1999
Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta.
    Biochimica et biophysica acta, 2000, Jun-01, Volume: 1466, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Carnitine; Carrier Proteins; Cloning, Molecular; DNA, Complementary; Humans; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Organic Cation Transport Proteins; Placenta; Rats; RNA, Messenger; Solute Carrier Proteins; Structure-Activity Relationship; Symporters; Tetraethylammonium; Tissue Distribution

2000
Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Binding, Competitive; Carbon Radioisotopes; Cations; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Dopamine Agents; Exons; Gene Expression Regulation; HeLa Cells; Herbicides; Humans; In Situ Hybridization; Introns; Kidney; Mice; Niacinamide; Octamer Transcription Factor-3; Oocytes; Pigment Epithelium of Eye; RNA, Messenger; Tetraethylammonium; Transcription Factors; Tritium; Xenopus laevis

2000
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
    Molecular pharmacology, 2001, Volume: 59, Issue:2

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium

2001
Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene.
    Molecular and cellular biology, 2001, Volume: 21, Issue:16

    Topics: Animals; Carrier Proteins; Cations; Intestinal Mucosa; Ion Transport; Liver; Membrane Proteins; Mice; Mice, Knockout; Organic Cation Transporter 1

2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:3

    Topics: Animals; Anions; Carrier Proteins; Cations; Cell Line; Cell Membrane; Choline; Cloning, Molecular; Female; Guanidine; Histamine; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Patch-Clamp Techniques; Quinine; Rats; Recombinant Proteins; Tetraethylammonium; Transfection; Xenopus laevis

2001
cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:7

    Topics: Alternative Splicing; Amino Acid Sequence; Base Sequence; Cations; Cell Line; Cloning, Molecular; DNA, Complementary; Genetic Variation; Humans; Kidney; Molecular Sequence Data; Organic Cation Transport Proteins; Organic Cation Transporter 2; Tetraethylammonium; Tissue Distribution; Transfection

2002
Functional characterization of mouse cation transporter mOCT2 compared with mOCT1.
    Biochemical and biophysical research communications, 2002, Aug-23, Volume: 296, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Base Sequence; Biological Transport; Cations; Cells, Cultured; Cloning, Molecular; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Membrane Potentials; Mice; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tetraethylammonium; Xenopus

2002
Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1.
    Molecular pharmacology, 2003, Volume: 63, Issue:3

    Topics: Computational Biology; HeLa Cells; Humans; Models, Molecular; Organic Cation Transporter 1; Pyridinium Compounds; Quinolinium Compounds; Structure-Activity Relationship; Transfection

2003
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
MPP+ is transported by the TEA(+)-H+ exchanger of renal brush-border membrane vesicles.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cations; Hydrogen; Hydrogen-Ion Concentration; Ions; Kidney; Kinetics; Microvilli; Osmolar Concentration; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors

1990
Peritubular paraquat transport in isolated renal proximal tubules.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Cations; In Vitro Techniques; Kidney Tubules, Proximal; Mitoguazone; Paraquat; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds

1995
Paraquat2+/H+ exchange in isolated renal brush-border membrane vesicles.
    Biochimica et biophysica acta, 1995, Nov-22, Volume: 1240, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Hydrogen-Ion Concentration; Kidney; Kinetics; Membrane Potentials; Membrane Proteins; Microvilli; Paraquat; Protons; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds

1995
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.
    Biochimica et biophysica acta, 1999, Mar-04, Volume: 1417, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Buffers; Carrier Proteins; Cells, Cultured; Hydrogen-Ion Concentration; Levofloxacin; Membrane Proteins; Ofloxacin; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Potassium; Rats; Tetraethylammonium; Transfection; Xenopus laevis

1999
Cloning and functional expression of a mouse liver organic cation transporter.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Carrier Proteins; Cations; Choline; Cloning, Molecular; Female; Kinetics; Liver; Membrane Potentials; Membrane Proteins; Mice; Molecular Sequence Data; Niacinamide; Oocytes; Organic Cation Transporter 1; Protons; Tetraethylammonium; Xenopus laevis

1999
Expression of the extraneuronal monoamine transporter in RPE and neural retina.
    Current eye research, 2000, Volume: 20, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amphetamine; Animals; Biogenic Monoamines; Blotting, Northern; Carrier Proteins; Cells, Cultured; Eye; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; In Situ Hybridization; Kinetics; Methamphetamine; Mice; Mice, Inbred ICR; Nicotine; Organic Cation Transport Proteins; Pigment Epithelium of Eye; Procainamide; Retina; RNA, Messenger; Steroids; Tetraethylammonium; Time Factors

2000
Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Biological Transport; Caco-2 Cells; Carrier Proteins; Cations; Cell Line; Clonidine; Corticosterone; DNA, Recombinant; Dose-Response Relationship, Drug; Gene Expression; Histamine; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines; Membrane Potentials; Membrane Proteins; Organic Cation Transport Proteins; Organic Cation Transporter 1; Plasmids; Quinolines; Quinolinium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Time Factors; Transfection; Tritium

2001
Transport of choline and its relationship to the expression of the organic cation transporters in a rat brain microvessel endothelial cell line (RBE4).
    Biochimica et biophysica acta, 2001, Jun-06, Volume: 1512, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Brain; Brain Stem; Carrier Proteins; Cell Line; Cerebrovascular Circulation; Choline; Clonidine; Endothelium, Vascular; Hemicholinium 3; Kidney; Kinetics; Membrane Proteins; Microcirculation; Organic Cation Transporter 1; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Tetraethylammonium; Transcription, Genetic

2001
Molecular cloning and functional characterization of the OCTN2 transporter at the RBE4 cells, an in vitro model of the blood-brain barrier.
    Brain research, 2003, Apr-04, Volume: 968, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Blood-Brain Barrier; Carnitine; Carrier Proteins; Cell Line; Choline; Cloning, Molecular; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; HeLa Cells; Humans; In Vitro Techniques; Kidney; Kinetics; Membrane Proteins; Models, Biological; Organic Cation Transport Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Solute Carrier Family 22 Member 5; Tetraethylammonium; Time Factors; Tissue Distribution; Transcription, Genetic; Transfection; Tritium

2003
A human transporter protein that mediates the final excretion step for toxic organic cations.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Dec-13, Volume: 102, Issue:50

    Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Sequence; Blotting, Northern; Blotting, Western; Cations; Cell Line; DNA Primers; DNA, Complementary; Humans; Immunohistochemistry; Kidney; Liver; Microscopy, Immunoelectron; Molecular Sequence Data; Mutagenesis; Organic Cation Transport Proteins; Protein Structure, Secondary; Substrate Specificity; Tetraethylammonium

2005
Identification and functional characterization of genetic variants of human organic cation transporters in a Korean population.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Asian People; Base Sequence; Cell Line; China; Dogs; Gene Frequency; Genotype; Humans; Kinetics; Korea; Linkage Disequilibrium; Microinjections; Molecular Sequence Data; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Phenotype; Polymorphism, Single Nucleotide; Tetraethylammonium; Transfection; Vietnam; Xenopus laevis

2007
Molecular identification and functional characterization of rabbit MATE1 and MATE2-K.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Algorithms; Amino Acid Sequence; Animals; Biological Transport, Active; CHO Cells; Cimetidine; Cloning, Molecular; Cricetinae; Cricetulus; Dopamine Agents; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Microvilli; Molecular Sequence Data; Organic Cation Transport Proteins; Protein Structure, Secondary; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Tetraethylammonium; Transfection

2007
Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
    Xenobiotica; the fate of foreign compounds in biological systems, 2007, Volume: 37, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biguanides; Cell Line; Cimetidine; Drug Design; Famotidine; Histamine H2 Antagonists; Humans; Ion Transport; Kinetics; Metformin; Organic Cation Transport Proteins; Phenformin; Ranitidine; Rats; Tetraethylammonium

2007
Predominant contribution of rat organic anion transporting polypeptide-2 (Oatp2) to hepatic uptake of beta-lactam antibiotics.
    Pharmaceutical research, 2008, Volume: 25, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anti-Bacterial Agents; beta-Lactams; Estrone; Female; Hepatocytes; Kinetics; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Proteins; Nafcillin; Oocytes; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfobromophthalein; Tetraethylammonium; Xenopus laevis

2008
Transcellular transport of organic cations in double-transfected MDCK cells expressing human organic cation transporters hOCT1/hMATE1 and hOCT2/hMATE1.
    Biochemical pharmacology, 2008, Oct-01, Volume: 76, Issue:7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; Cimetidine; Dogs; Humans; Metformin; Octamer Transcription Factor-1; Organic Cation Transport Proteins; Organic Cation Transporter 2; Procainamide; Quinidine; Tetraethylammonium; Transfection

2008
Identification and characterization of 3-iodothyronamine intracellular transport.
    Endocrinology, 2009, Volume: 150, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Acyclovir; Biological Transport; Carnitine; Cell Line; Equilibrative-Nucleoside Transporter 2; Estrone; HeLa Cells; Humans; Hydrogen-Ion Concentration; Membrane Transport Proteins; Monocarboxylic Acid Transporters; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 1; RNA Interference; RNA, Small Interfering; Symporters; Tetraethylammonium; Thyronines

2009
Selective transport of monoamine neurotransmitters by human plasma membrane monoamine transporter and organic cation transporter 3.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Adrenal Glands; Animals; Biogenic Monoamines; Biological Transport; Brain; DNA Nucleotidyltransferases; Dopamine; Epinephrine; Equilibrative Nucleoside Transport Proteins; Female; Gene Expression; HEK293 Cells; Histamine; Humans; Kinetics; Male; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Muscle, Skeletal; Neurotransmitter Agents; Norepinephrine; Organic Cation Transport Proteins; Serotonin; Synaptosomes; Tetraethylammonium; Transfection

2010
Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; 3-Iodobenzylguanidine; Animals; Binding, Competitive; Biological Transport; Cephalexin; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; HEK293 Cells; Humans; Kidney; Kinetics; Liver; Male; Metformin; Mice; Mice, Inbred Strains; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Pyridines; Tetraethylammonium; Transfection

2012
Genetic variants of organic cation transporter 1 (OCT1) and OCT2 significantly reduce lamivudine uptake.
    Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:3

    Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Substitution; Asian People; Humans; Lamivudine; Metformin; Oocytes; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Polymorphism, Single Nucleotide; Tetraethylammonium

2012
Functional significance of conserved cysteines in the human organic cation transporter 2.
    American journal of physiology. Renal physiology, 2012, Jul-15, Volume: 303, Issue:2

    Topics: 1-Methyl-4-phenylpyridinium; Alanine; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Cricetinae; Cricetulus; Cysteine; Female; Humans; Mutation; Organic Cation Transport Proteins; Organic Cation Transporter 2; Ovary; Phenylalanine; Tetraethylammonium; Transfection

2012
Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2.
    American journal of physiology. Renal physiology, 2013, Jan-01, Volume: 304, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Androstenes; Animals; Benzhydryl Compounds; Carbazoles; Carvedilol; CHO Cells; Cimetidine; Cricetinae; Cricetulus; Humans; Inhibitory Concentration 50; Kinetics; Ligands; Metformin; Organic Cation Transport Proteins; Organic Cation Transporter 2; Piperidines; Propanolamines; Tetraethylammonium

2013
Unstirred Water Layers and the Kinetics of Organic Cation Transport.
    Pharmaceutical research, 2015, Volume: 32, Issue:9

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Cell Line; CHO Cells; Cricetulus; Kinetics; Organic Cation Transport Proteins; Tetraethylammonium; Water

2015
Urinary Excretion of Tetrodotoxin Modeled in a Porcine Renal Proximal Tubule Epithelial Cell Line, LLC-PK₁.
    Marine drugs, 2017, Jul-17, Volume: 15, Issue:7

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Carnitine; Cell Line; Epithelial Cells; Kidney Tubules, Proximal; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Probenecid; Renal Elimination; Swine; Tetraethylammonium; Tetrodotoxin

2017