tetradecanoylphorbol acetate has been researched along with ucn 1028 c in 289 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 210 (72.66) | 18.2507 |
| 2000's | 69 (23.88) | 29.6817 |
| 2010's | 9 (3.11) | 24.3611 |
| 2020's | 1 (0.35) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez Del Castillo, A; Trifaró, JM; Vitale, ML | 1 |
| García-Sáinz, JA; López-Gómez, FJ; Robles-Flores, M | 1 |
| Chan, CK; Downey, GP; Grinstein, S; Lea, P; Takai, A | 1 |
| Luna, EJ; Shariff, A | 1 |
| Chambers, TC; Kuo, JF; Zheng, B | 1 |
| Park, HY; Sampson, PH; Scheidl, H; Scita, G; Wolf, G | 1 |
| Lechene, C; Schwartz, MA | 1 |
| Durum, SK; Kung, HF; Ramsburg, EA; Smith, MR | 1 |
| Haynes, DH; Johansson, JS; Tao, J | 1 |
| Chakrabarty, S | 1 |
| Messina, JL | 1 |
| Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y | 3 |
| Choi, B; Chun, JS; Kang, SS; Lee, YS; Sonn, JK | 1 |
| Brooks, PC; Cheresh, DA; Friedlander, M; Kincaid, CM; Shaffer, RW; Varner, JA | 1 |
| Benveniste, EN; Norris, JG; Sparacio, SM; Tang, LP | 1 |
| Golard, A; Role, LW; Siegelbaum, SA | 1 |
| Artini, M; Avantaggiati, ML; Balsano, C; Chirillo, P; Costanzo, A; Levrero, M; Natoli, G | 1 |
| Aguila-Mansilla, N; Kedzierski, W; Kozlowski, GP; Porter, JC | 1 |
| Aglietta, M; Arese, M; Bussolino, F; Camussi, G; Costamagna, C; Garbarino, G; Pescarmona, G; Sanavio, F; Silvagno, F; Soldi, R | 1 |
| Gaudette, DC; Holub, BJ; Kirkland, JB; Turini, ME | 1 |
| Hoffman, PL; Iorio, KR; Snell, LD; Tabakoff, B | 1 |
| Malbon, CC; Strassheim, D | 1 |
| Aviv, A; Benevenia, J; Fekete, Z; Gardner, J; Yang, XY | 1 |
| Arbiser, JL; Bruijn, JA; Byers, HR; Dekker, SK; van Leeuwen, RL; Vermeer, BJ | 1 |
| Isosaki, M; Minami, N; Nakashima, T | 1 |
| Thurston, G; Turner, D | 1 |
| Campenot, RB; Draker, DD; Senger, DL | 1 |
| Geng, YJ; Hansson, GK; Wu, Q | 1 |
| Allen, JM; Balbi, D | 1 |
| Balch, WE; Bannykh, S; Fabbri, M | 1 |
| Fumo, P; Kuncio, GS; Ziyadeh, FN | 1 |
| Rozanski, GJ; Witt, RC | 1 |
| Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M | 1 |
| Asaoka, Y; Chang, WC; Liu, YW; Suzuki, H; Yamamoto, S; Yoshimoto, T | 1 |
| Mühl, H; Pfeilschifter, J | 1 |
| Homma, MK; Krebs, EG; Marumo, F; Nonoguchi, H; Sasaki, S; Terada, Y; Tomita, K; Yamada, T; Yang, T; Yuasa, Y | 1 |
| Oliver, M; Radzioch, D; Reiner, G; Skamene, E | 1 |
| Fujimoto, K; Ikeda, C; Kawashima, K; Mori, A; Morita, I; Murota, S; Suzuki, T | 1 |
| Huang, MH; Riedel, H; Rotenberg, SA; Su, L; Zhu, J | 1 |
| Fandrey, J; Frede, S; Jelkmann, W | 1 |
| Henrion, D; Laher, I | 1 |
| Miller, LJ; Ozcelebi, F | 1 |
| Cano, C; Malik, KU; Slavik, KJ | 1 |
| Fan, TP; Hu, DE | 1 |
| Bell, LL; Cheung, JY; Lynch, CJ; Miller, BA | 1 |
| Bartschat, DK; Rhodes, TE | 1 |
| Guillemain, I; Rossignol, B | 1 |
| Blume-Jensen, P; Heldin, CH; Rönnstrand, L; Wernstedt, C | 1 |
| Adachi, K; Asano, H; Hamaguchi, M; Ito, T; Koizumi, KT; Murate, T; Saga, S; Saito, H; Watanabe, T; Yoshida, S | 1 |
| Bitrick, MS; Smith, TL | 1 |
| Horzempa, C; McKeown-Longo, PJ; Panetti, TS; Wilcox, SA | 1 |
| Barman, SA; Ikeda, SR | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 1 |
| Dive, C; Evans, CA; Johnson, G; Lord, JM; Owen-Lynch, PJ; Whetton, AD | 1 |
| Baldo, A; Cianflone, K; Sniderman, AD; St Luce, S; Zhang, XJ | 1 |
| Abe, M; Hiraoka, M; Miyakoshi, J; Ohtsu, S; Takebe, H; Tsukada, T | 1 |
| Hales, DB; Li, X; Payne, AH; Youngblood, GL | 1 |
| Aburto, T; Deth, RC; Jinsi, A; Zhu, Q | 1 |
| Levine, AE; Ramesh, G | 1 |
| Aquino, A; Leonetti, C; Tentori, L | 1 |
| Akard, L; Cui, Y; English, D; Garcia, JG; Harvey, K; Jansen, J; Martin, MI; Siddiqui, RA; Thompson, J; Wentland, J | 1 |
| Chong, AS; Curry, MS; Edwards, BS; Graf, LH; Southon, EA | 1 |
| Abayasekara, RE; Flint, AP; Searle, MJ | 1 |
| Indelicato, SR; Kirk, G; Kitamura, T; Meyer, L; Miyajima, A; Muir, VC; Parce, JW; Wada, HG | 1 |
| Azzi, A; Boscoboinik, D; Galeotti, T | 1 |
| Baglioni, C; Gorospe, M; Kumar, S | 1 |
| Allon, M; Parris, M | 1 |
| Kinney, GA; Slater, NT | 1 |
| Bischer, P; Cantu, AR; Pavone, A; Reiners, JJ; Schöller, A | 1 |
| Niedbala, MJ; Stein-Picarella, M | 1 |
| Bongrand, P; Bouhamdan, M; Capo, C; Huang, CK; Mege, JL; Sanguedolce, MV | 1 |
| Gotoh, H; Kamiyama, A; Kashimoto, T; Sawada, M; Shibayama, R | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Boyd, D; Clayman, G; Juarez, J; Nakajima, M; Nicolson, GL; Saya, H; Tanabe, KK | 1 |
| Malik, KU; Nebigil, C | 1 |
| De Matteis, MA; Di Tullio, G; Kahn, RA; Luini, A; Santini, G | 1 |
| Audesirk, G; Cabell, L | 1 |
| Ruoslahti, E; Vuori, K | 1 |
| De Pont, JJ; Hoenderop, JG; Van Emst-De Vries, SE; Van Hoof, HJ; Van Mackelenbergh, MG; Willems, PH | 1 |
| Aquino, A; Grimaldi, S; Lisi, A; Pozzi, D; Ravagnan, G | 1 |
| Dussault, JH; Etongue-Mayer, P; Puymirat, J | 1 |
| Amino, K; Fujimoto, T; Honda, Y; Takahashi, M | 1 |
| Bosche, MC; Levine, RA; Nandi, J; Rotker, JD; Strapko, A | 1 |
| Coskun, S; Lin, YC | 1 |
| Gopalakrishna, R; Gundimeda, U; He, S; Hinton, DR; Hofman, FM; Ryan, SJ; Sippy, BD; Wang, JL; Wright, AD | 1 |
| Goracci, G; Gresele, P; Iorio, P; Nenci, GG; Nucciarelli, F; Stasi, M; Vezza, R | 1 |
| Azzi, A; Bartoli, GM; Boscoboinik, D; Maroni, P; Tasinato, A | 1 |
| Koga, Y; Kubo, C; Nomoto, K; Okumura, Y; Sudo, N; Tanaka, K | 1 |
| Chikvashvili, D; Levin, G; Lotan, I; Moran, O; Peretz, T; Thornhill, WB | 1 |
| Nishikawa, T; Omura, M; Sasano, H; Suematsu, S | 1 |
| Floyd-Smith, G; Shih, NY | 1 |
| Daphna-Iken, D; Morrison, AR; Rzymkiewicz, DM; Srivastava, S; Tetsuka, T | 1 |
| Fuhrer, DK; Hamilton, J; Steussy, CN; Yang, L; Yang, YC | 1 |
| Daniels, I; Fletcher, J; Lindsay, MA | 1 |
| Kondo, T; Murakami, K; Ueno, A; Watanabe, M; Yamanouchi, K | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B; Taniguchi, N | 1 |
| Collombel, C; Damour, O; Nakazawa, H; Nakazawa, K; Sahuc, F | 1 |
| Balasubramanyam, M; Gardner, JP | 1 |
| Cartouzou, G; Colombani, V; Gerolami, A; Heyries, L; Marteau, C; Silviani, V | 1 |
| Ha, H; Kamanna, VS; Kirschenbaum, MA; Pai, R | 1 |
| Bédard, PA; Bojović, B; Dehbi, M; Rodrigues, N | 1 |
| Bérubé, G; Coqueret, O; Nepveu, A | 1 |
| Chang, JP; Jobin, RM; Neumann, CM; Van Goor, F | 1 |
| Hu, YH; Offermanns, S; Simon, MI | 1 |
| Lee, SC; Yang, SD | 1 |
| Chopra, DP; Levine, SJ; Logun, C; Rhim, JS; Shelhamer, JH | 1 |
| Jensen, PE | 1 |
| Bardes, ES; Bell, RM; Buehrer, BM | 1 |
| Kan, H; Malik, KU; Ruan, Y | 1 |
| Higashiyama, M; Ishikawa, SE; Kusaka, I; Nagasaka, S; Saito, T | 1 |
| He, S; Hinton, DR; Hofman, FM; Ryan, SJ; Sippy, BD; Wright, AD | 1 |
| Packer, CS; Rhoades, RA; Zhao, Y | 1 |
| Lu, M; Wang, W | 1 |
| Kusaka, M; Sperelakis, N | 1 |
| Akasaka, R; Ikebuchi, H; Sawada, J; Teshima, R | 1 |
| Murayama, T; Nomura, Y; Oda, H | 1 |
| Asaka, M; Iwasaki, H; Kato, K; Kawamura, K; Kobayashi, M; Miyazaki, T; Musashi, M; Sakurada, K; Sasaki, M; Sudo, T; Tanaka, E; Tsuda, Y | 1 |
| Gillette, MU; Hunt, AE; McArthur, AJ | 1 |
| Dickens, G; Guroff, G; Lavarreda, M; Zheng, WH | 1 |
| Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Small, D; Song, D; Tremblay, R | 1 |
| Avraham, H; Avraham, S; Fu, Y; Hiregowdara, D; London, R | 1 |
| Eberhardt, RT; von Andrian, L; Ware, JA; Yokota, R; Yukawa, M | 1 |
| Kozawa, O; Suzuki, A; Tokuda, H; Uematsu, T | 1 |
| Doherty, K; Paul, A; Plevin, R | 1 |
| Brown, ER; Dempsey, BK; Lew, DB; Malik, KU; Wright, HM | 1 |
| Inagaki, C; Mishima, K; Ogawa, R; Otani, H; Tanabe, T | 1 |
| Cánepa, ET; Varone, CL | 1 |
| Bitar, KN; Hajra, A; Sbrissa, D; Yamada, H | 1 |
| Acevedo-Duncan, M; Cooper, DR; Greenberg, HM; Zhang, R | 1 |
| Fraser, LR; O'Toole, CM; Roldan, ER | 1 |
| Higashiyama, S; Ito, N; Kawata, S; Kiso, S; Matsuzawa, Y; Nakagawa, T; Tamura, S; Taniguchi, N; Tsushima, H | 1 |
| Dellsperger, KC; Gutterman, DD; Miller, FJ | 1 |
| Figueroa, JE; Glancy, DL; Smart, FW; Tao, Z; Vijayagopal, P | 1 |
| Corbett, JA; Hansen, PA; Holloszy, JO | 1 |
| Floyd-Smith, G; Yu, F | 1 |
| Brindley, DN; Ginsberg, J; Gupta, S; Kline, L; Matowe, WC | 1 |
| Aballay, A; Arenas, NG; Mayorga, LS; Quest, AF | 1 |
| Levi, G; Patrizio, M; Slepko, N | 1 |
| Goetz, FW; Planas, JV; Swanson, P | 1 |
| Chen, C; Clarke, IJ; Wu, D | 1 |
| Byers, SW; Crockett, C; Jensen, JP; Orford, K; Weissman, AM | 1 |
| Collier, FM; Herbst, RE; Hodge, JM; Holloway, WR; Nicholson, GC | 1 |
| Goode, N; Keenan, C; Pears, C | 2 |
| Bongrand, P; Lissitzky, JC; Masson-Gadais, B; Salers, P | 1 |
| Fujita, M; Murata, M; Nagai, M; Ohmori, M; Takahara, J | 1 |
| Gekle, M; Oberleithner, H; Silbernagl, S | 1 |
| Delacourt, C; Delclaux, C; Harf, A; L'Hour, J; Lafuma, C; Rouet-Benzineb, P | 1 |
| Ito, H; Spurzem, JR; Veys, TJ; Wyatt, TA | 1 |
| Chun, JS; Kim, JY; Lee, YS; Park, J | 1 |
| Chambers, TC; Cloud-Heflin, BA; Kumar, A; Mehta, KD | 1 |
| Choe, YS; Kim, K; Lee, YJ; Sun, W | 1 |
| Behrend, EN; Kemppainen, RJ | 1 |
| Fukuzawa, K; Houchi, H; Oka, M; Okuno, M; Tokumura, A; Tsuchiya, K | 1 |
| Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X | 1 |
| Gnegy, ME; Kantor, L | 1 |
| Ohnishi, K; Ohnishi, T; Takahashi, A; Wang, X | 1 |
| Bearz, A; Colombatti, A; Formisano, S; Pucillo, C; Tell, G | 1 |
| Kiang, DT; Li, GY; Lin, HH; Tu, ZJ | 1 |
| Kucera, GL; Stadheim, TA | 1 |
| Hayakawa, T; Kasugai, I; Kawanishi, T; Morimoto, K | 1 |
| Bandoh, S; Miyakoshi, J; Tachiiri, S; Takebe, H; Tsukada, T; Yamaguchi, K | 1 |
| Baekgaard, A; Bindslev, N | 1 |
| Inoguchi, T; Kuroki, T; Nawata, H; Ueda, F; Umeda, F | 1 |
| Cha, DR; Cho, BS; Ha, H; Hong, SP; Ihm, CG; Kim, MJ; Lee, TW; Park, JK | 1 |
| Gierow, JP; Mircheff, AK | 1 |
| Devoe, G; Gear, R; Heffelfinger, SC; Miller, MA | 1 |
| Ao, P; Boynton, AL; Hossain, MZ | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| Hamada, JI; Hosokawa, M; Kimura, K; Kobayashi, M; Li, YQ; Matsushita, K; Okumura, K; Wang, J; Yagita, H; Yuan, L | 1 |
| Greene, R; Hales, DB | 1 |
| Barnum, SR; Carlino, JA; Drouin, SM; Kiley, SC | 1 |
| MacGlashan, DW; Miura, K | 1 |
| Alonso, M; Hall, C; Hidalgo, J; Muñiz, M; Velasco, A | 1 |
| Allen, RG; Cristofalo, VJ; Furth, JJ; Keogh, B; Tresini, M | 1 |
| Itoh, H; Kaziro, Y; Nagao, M; Yamauchi, J | 1 |
| Mayne, GC; Murray, AW | 1 |
| Chik, CL; Ho, AK; Negishi, T; Ogiwara, T | 1 |
| Amlal, H; Goel, A; Soleimani, M | 1 |
| Accornero, P; Carè, A; Chiodoni, C; Colombo, MP; Kurrle, R; Mattia, G; Radrizzani, M | 1 |
| Kravtsov, GM; Kwan, CY | 1 |
| Hagiwara, Y; Hanada, M; Kambe, T; Kubo, T; Saito, E | 1 |
| Katsuki, H; Matsuki, N; Saito, H; Shitaka, Y | 1 |
| Kiuchi, Y; Oguchi, K; Ohno, M; Uchida, J; Yura, A | 1 |
| Hashimoto, T; Hojo, K; Kawamata, T; Maeda, K; Nakai, M; Tanaka, C; Taniguchi, T; Terashima, A | 1 |
| Hiraoka, S; Kitamura, S; Matsuzawa, Y; Miyazaki, Y; Shinomura, Y; Tsutsui, S | 1 |
| Abe, S; Hino, T; Inage, M; Kato, S; Nakamura, H; Saito, H; Terashita, K; Tomoike, H | 1 |
| Fujita, T; Mine, T; Ohnishi, H; Shibata, H; Tsuchida, T; Ueda, N | 1 |
| Akiyama, SK; Dickson, RB; Johnson, MD; Maemura, M; Rosfjord, EC; Torri, JA; Woods, VL | 1 |
| Breitbart, H; Rubinstein, S; Sun, QY | 1 |
| Kawamura, H; Kozawa, O; Matsui, N; Matsuno, H; Niwa, M; Otsuka, T; Tokuda, H; Uematsu, T | 1 |
| Dessauer, CW; Hume, JR; Keef, KD; Zhong, J | 1 |
| Beckman, BS; Fisher, JW; Mallia, CS; McGary, E; Ohigashi, T; Rondon, I; Scandurro, AB | 1 |
| Aballay, A; Mayorga, LS; Stahl, PD | 1 |
| Boland, RL; Capiati, DA; Limbozzi, F; Téllez-Iñón, MT | 1 |
| Araki, E; Furukawa, N; Kaneko, K; Kishikawa, H; Matsumoto, K; Motoshima, H; Shichiri, M; Shirotani, T; Todaka, M; Tsuruzoe, K; Yoshizato, K | 1 |
| Buchan, AM; Meloche, RM; Moore, ED; Ring, M; Scriven, DR; Smith, VC | 1 |
| Kozawa, O; Miwa, M; Tokuda, H; Uematsu, T | 1 |
| Inoue, T; Koono, M; Nabeshima, K; Shimao, Y | 1 |
| Kontny, E; Maśliński, W; Ryzewska, A; Ziółkowska, M | 1 |
| Brown, TL; Sahni, SK; Sporn, LA; Turpin, LC | 1 |
| Ikeda, K; Kaneko, YS; Nakanishi, M | 1 |
| Knox, FG; Liang, M | 1 |
| Di Battista, JA; He, Y; Martel-Pelletier, J; Miller, C; Pelletier, JP; Zhang, M | 1 |
| Josefsen, D; Myklebust, JH; Sioud, M; Smeland, EB | 1 |
| Ishikawa, K; Okajima, F; Sato, K; Ui, M | 1 |
| Chakrabarti, R; Kumar, S | 1 |
| Adlersberg, M; Gershon, MD; Hsiung, S; Liu, K; Sacktor, T; Tamir, H | 1 |
| Huang, CS; Marszalec, W; Narahashi, T; Song, JH; Uenishi, H | 1 |
| Alexander, SR; Kishimoto, TK; Walcheck, B | 1 |
| Chen, X; Tang, S; Tashjian, AH | 1 |
| Allen, JC; Kahn, AM; Seidel, CL; Song, T | 1 |
| Bao, HF; Eaton, DC; Malik, B; Middleton, P; Schenck, J; Schlanger, LE; Stockand, JD | 1 |
| Kondo, I | 1 |
| Hatakeyama, D; Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T | 1 |
| Barlow, RS; El-Mowafy, AM; White, RE | 1 |
| Ahn, DH; Baek, SH; Chae, HS; Erickson, RH; Han, SY; Kim, HR; Kim, YS; Lee, MS; Sleisenger, MH | 1 |
| Davis, HW; Zhao, Y | 1 |
| Grider, JR; Makhlouf, GM; Murthy, KS | 1 |
| Brown, PD; Kajita, H; Whitwell, C | 1 |
| Fenton, MJ; Ritzenthaler, JD; Roman, J; Roser, S; Schuyler, W | 1 |
| Cheng, S; Mao, J; Rehder, V | 1 |
| Mancuso, P; Peters-Golden, M | 1 |
| Aguayo, C; Flores, C; Mann, GE; Montecinos, VP; Pearson, JD; Sobrevia, L; Wyatt, AW | 1 |
| Ostergaard, HL; Puente, LG; Stone, JC | 1 |
| Ma, R; Sansom, SC | 1 |
| Katsuyama, R; Kawasaki, T; Morioka, A; Oka, S | 1 |
| Cho, S; Choe, Y; Kim, DH; Kim, K; Lee, H; Sun, W | 1 |
| Boland, R; Buitrago, C; de Boland, AR; Morelli, S | 1 |
| Klemm, J; Rådmark, O; Samuelsson, B; Werz, O | 1 |
| Beauchemin, N; Fournès, B; Létourneau, S; Sadekova, S; Turbide, C | 1 |
| Chen, DY; Han, ZM; Lu, Q; Schatten, H; Smith, GD; Sun, QY; Yang, Z | 1 |
| Kuznetsova, LA; Pertseva, MN; Plesneva, SA; Shpakov, AO | 2 |
| Ellis, CA; Kouklis, P; Malik, AB; Minshall, RD; Sandoval, R; Tiruppathi, C | 1 |
| Azzi, A; Breyer, I | 1 |
| Capito, K; Thams, P | 1 |
| Donin, N; Fishelson, Z; Jurianz, K; Kirschfink, M; Reiter, Y; Ziegler, S | 1 |
| Aksoy, MO; Bin, W; Kelsen, SG; Yang, Y; Yun-You, D | 1 |
| Asano, Y; Ishibashi, S; Miyata, Y; Muto, S; Okada, K | 1 |
| Lange, Y; Steck, TL; Ye, J | 1 |
| Chang, Z; Feng, W; Gao, L; Li, C; Li, M; Shao, J; Wang, S; Wang, X; Wang, Y; Zhang, J | 1 |
| Aizawa, T; Hashiguchi, S; Hashizume, K; Komatsu, M; Sato, Y; Yada, T; Yajima, H; Yamada, S; Yamauchi, K | 1 |
| He, S; Li, X; Zhao, M | 1 |
| Chabot, S; Hirashima, M; Kashio, Y; Matsumoto, R; Nakamura, K; Nakamura, T; Nishi, N; Seki, M; Shirato, Y | 1 |
| Alonso, I; Garcia, N; González, CM; Lanuza, MA; Nelson, PG; Santafé, M; Tomàs, J | 1 |
| Flamand, L; Gosselin, J; Savard, M; Tardif, M | 1 |
| Wang, N; Xu, YH | 1 |
| Kivilaakso, E; Kiviluoto, T; Mustonen, H; Puolakkainen, P; Ranta-Knuuttila, T; Sato, N; Watanabe, S | 1 |
| Ellershaw, DC; Greenwood, IA; Large, WA | 1 |
| Fong, TH; Greenberg, AS; Wang, SM; Yang, CC | 1 |
| de Jong, K; Kuypers, FA; Low, PS; Rettig, MP | 1 |
| Aki, T; Uemura, K; Yamaguchi, K; Yoshida, Ki | 1 |
| Dobashi, H; Ishida, H; Ishida, T; Kitanaka, A; Kubo, A; Kubota, Y; Matsumoto, A; Ohnishi, H; Tanaka, T; Tokuda, M; Waki, M | 1 |
| Brzóska, E; Grabowska, I; Moraczewski, J; Wróbel, E | 1 |
| Ito, J; Shimada, M; Terada, T | 1 |
| Ito, H; Kato, K; Kozawa, O; Niwa, M; Oiso, Y; Tokuda, H | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| John, SA; Kodama, I; Lee, JK; Uozumi, N; Zhang, L | 1 |
| Khalil, RA; McNair, LL; Salamanca, DA | 1 |
| Huang, SH; Shen, WJ; Wang, SM; Yeo, HL | 1 |
| Ajioka, H; Akizawa, Y; Kanda, A; Kiniwa, M; Matsuura, N; Nakano, M; Nishihara, K; Nozawa, Y; Orimoto, N; Uji, T | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Li, B | 1 |
| Jackson, AD; Kemp, PA; Sugar, RA | 1 |
| Chen, CC; Guo, YJ; Huang, GJ; Tang, KT; Tung, WH; Wang, HS; Wong, YK; Wu, JC | 1 |
| Hammoudi, DS; Mandelcorn, MS; Munk, S; Wang, H; Whiteside, CI; Young, DS; Young, TA | 1 |
| Bakker, AJ; Han, R | 1 |
| Canaff, L; Chihara, K; Hendy, GN; Kaji, H; Naito, J; Sowa, H; Sugimoto, T; Tobimatsu, T | 1 |
| Alonso, MJ; Beltrán, A; Manso, AM; Pacheco, ME; Redondo, J; Salaices, M | 1 |
| Joy, KP; Mishra, A | 1 |
| Delgado, DH; Miriuka, S; Ramzy, D; Rao, V; Ross, HJ; Sheshgiri, R; Tumiati, LC; Xu, N | 1 |
| Brayden, JE; Corteling, RL; Giles, WR; Luykenaar, KD; Welsh, DG; Wiehler, WB; Wu, BN | 1 |
| Almeida-Amaral, EE; Caruso-Neves, C; Lara, LS; Meyer-Fernandes, JR; Pinheiro, CM | 1 |
| Berg, DT; Calnek, D; Grinnell, BW; Gupta, A; O'Brien, LA; Richardson, MA | 1 |
| Kawano, T; Mawatari, K; Nakaya, Y; Oshita, S; Takahashi, A; Tanaka, K | 1 |
| Clark, OH; Duh, QY; Herfarth, C; Hoelting, T | 1 |
| Garcia, N; Lanuza, MA; Santafé, MM; Tomàs, J; Tomàs, M | 1 |
| Chen, WD; Gao, PJ; Han, WQ; Li, JD; Wu, LY; Yan, C; Zhang, J; Zhou, HY; Zhu, DL | 1 |
| Dreyer, I; Gambale, F; Sato, A; Uozumi, N | 1 |
| Nsaif, RH; Oyekan, AO; Yakubu, MA | 1 |
| Adderley, SP; Bowles, EA; Ellsworth, ML; Sprague, RS; Sridharan, M; Stephenson, AH | 1 |
| Chiba, S; Kozuma, Y; Ninomiya, H; Sawahata, Y; Takei, Y | 1 |
| Buléon, C; Galera, P; Gérard, JL; Hanouz, JL; Lemoine, S; Massetti, M; Zhu, L | 1 |
| De Marco, C; De Vita, F; Malanga, D; Riccardi, M; Scrima, M; Viglietto, G | 1 |
| Akaaboune, M; Martinez-Pena y Valenzuela, I; Pires-Oliveira, M | 1 |
| Asanidze, S; Bernhardt, I; Ghashghaeinia, M; Hanf, B; Kaestner, L; Mohamed, N; Mutua, J; Nguyen, DB; Wagner-Britz, L; Wesseling, MC | 1 |
| Leng, TD; Li, J; Xiong, ZG; Yang, T; Zhang, L | 1 |
1 trial(s) available for tetradecanoylphorbol acetate and ucn 1028 c
| Article | Year |
|---|---|
Effect of protein kinase C activator on mitogen-activated protein kinase and p34(cdc2) kinase activity during parthenogenetic activation of porcine oocytes by calcium ionophore.
Topics: Animals; Calcium; Calcium Signaling; CDC2 Protein Kinase; Cell Nucleus; Cell Separation; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Metaphase; Mitogen-Activated Protein Kinases; Naphthalenes; Oocytes; Parthenogenesis; Swine; Tetradecanoylphorbol Acetate | 2003 |
288 other study(ies) available for tetradecanoylphorbol acetate and ucn 1028 c
| Article | Year |
|---|---|
Protein kinase C activation by phorbol esters induces chromaffin cell cortical filamentous actin disassembly and increases the initial rate of exocytosis in response to nicotinic receptor stimulation.
Topics: Actins; Adrenal Medulla; Alkaloids; Animals; Calcium; Cattle; Enzyme Activation; Exocytosis; Kinetics; Macromolecular Substances; Microscopy, Fluorescence; Naphthalenes; Nicotine; Norepinephrine; Polycyclic Compounds; Protein Kinase C; Receptors, Nicotinic; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Staurosporine and calphostin-C inhibit the phorbol ester-induced decrease of protein kinase C activity in rat hepatocytes.
Topics: Alkaloids; Animals; Chromatography, DEAE-Cellulose; Enzyme Activation; Female; Liver; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Membrane; Diglycerides; Enzyme Activation; Humans; Isoquinolines; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Naphthalenes; Neutrophils; Piperazines; Polycyclic Compounds; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Diacylglycerol-stimulated formation of actin nucleation sites at plasma membranes.
Topics: Actins; Alkaloids; Animals; Calcium; Cell Membrane; Dictyostelium; Diglycerides; Kinetics; Macromolecular Substances; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Ethers, Cyclic; Humans; KB Cells; Membrane Glycoproteins; Naphthalenes; Okadaic Acid; Peptide Mapping; Phenotype; Phospholipid Ethers; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vinblastine | 1992 |
The effect of sphingosine and phorbol ester on the signal transduction enzymes and fibronectin release in cell culture.
Topics: Cell Line; Cyclic AMP; Enzyme Activation; Fibroblasts; Fibronectins; Humans; Isoquinolines; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor.
Topics: Acid-Base Equilibrium; Animals; Carrier Proteins; Cell Adhesion; Cells, Cultured; Extracellular Matrix; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Naphthalenes; Platelet-Derived Growth Factor; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1992 |
Components of the protein kinase C pathway induce Ia expression after injection into macrophages.
Topics: Alkaloids; Animals; Calcimycin; Diglycerides; Histocompatibility Antigens Class II; In Vitro Techniques; Interferon-gamma; Isoquinolines; Macrophages; Mice; Mice, Inbred C3H; Microinjections; Naphthalenes; Phospholipases A; Phospholipases A2; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins p21(ras); Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Protein kinase C stimulates dense tubular Ca2+ uptake in the intact human platelet by increasing the Vm of the Ca(2+)-ATPase pump: stimulation by phorbol ester, inhibition by calphostin C.
Topics: Blood Platelets; Calcium; Calcium-Transporting ATPases; Depression, Chemical; Fluorometry; Humans; In Vitro Techniques; Kinetics; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Role of protein kinase C in transforming growth factor-beta 1 induction of carcinoembryonic antigen in human colon carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoembryonic Antigen; Colonic Neoplasms; Humans; Isoquinolines; Naphthalenes; Piperazines; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Rapid regulation of albumin transcription by insulin and phorbol esters in rat hepatoma cells.
Topics: Albumins; Alkaloids; Animals; Cycloheximide; Gene Expression Regulation; Insulin; Kinetics; Liver Neoplasms, Experimental; Naphthalenes; Phosphoenolpyruvate Carboxykinase (GTP); Polycyclic Compounds; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Participation of protein kinase C in endothelin-1-induced contraction in rat aorta: studies with a new tool, calphostin C.
Topics: Animals; Aorta; Calcium; Endothelins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoconstriction | 1992 |
Expression of protein kinase C isozymes that are required for chondrogenesis of chick limb bud mesenchymal cells.
Topics: Animals; Cartilage; Cell Differentiation; Cells, Cultured; Chick Embryo; Diterpenes; Enzyme Inhibitors; Indoles; Isoenzymes; Limb Buds; Maleimides; Mesoderm; Naphthalenes; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Definition of two angiogenic pathways by distinct alpha v integrins.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Cornea; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblast Growth Factor 2; Integrins; Lymphokines; Naphthalenes; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptides, Cyclic; Protein Kinase C; Rabbits; Receptors, Vitronectin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha.
Topics: Animals; Animals, Newborn; Astrocytes; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Interleukin-1; Interleukin-6; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rats; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Protein kinase C blocks somatostatin-induced modulation of calcium current in chick sympathetic neurons.
Topics: Animals; Calcium Channels; Chick Embryo; Electric Stimulation; Enzyme Activation; Ganglia, Sympathetic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Lactams; Naphthalenes; Neurons; Polycyclic Compounds; Protein Kinase C; Receptors, Somatostatin; Somatostatin; Sympathetic Nervous System; Tetradecanoylphorbol Acetate | 1993 |
Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX.
Topics: Alkaloids; Animals; Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; HeLa Cells; Hepatitis B virus; Humans; Isoquinolines; Kinetics; Macromolecular Substances; Molecular Sequence Data; Naphthalenes; Oligodeoxyribonucleotides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Sphingosine; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Vaccinia virus; Viral Regulatory and Accessory Proteins | 1994 |
Expression of tyrosine hydroxylase gene in cultured hypothalamic cells: roles of protein kinase A and C.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dihydroxyphenylalanine; Dopamine; Gene Expression; Hypothalamus; Naphthalenes; Neurons; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1994 |
Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.
Topics: Actins; Amino Acid Sequence; Antibodies; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cytoskeletal Proteins; Cytosol; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Ginkgolides; Humans; Isoenzymes; Kinetics; Lactones; Molecular Sequence Data; Naphthalenes; Peptides; Phospholipid Ethers; Platelet Activating Factor; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thiazoles; Vinculin | 1994 |
Correlation between platelet aggregation and dephosphorylation of a 68 kDa protein revealed through the use of putative PKC inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Benzophenanthridines; Blood Proteins; Humans; Male; Molecular Weight; Naphthalenes; Phenanthridines; Phosphorus Radioisotopes; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1993 |
Protein kinase C activation attenuates N-methyl-D-aspartate-induced increases in intracellular calcium in cerebellar granule cells.
Topics: Alkaloids; Animals; Calcium; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Enzyme Activation; Glycine; Intracellular Fluid; Kinetics; Magnesium Sulfate; N-Methylaspartate; Naphthalenes; Neurons; Pipecolic Acids; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
Topics: Adenylyl Cyclases; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Ethers, Cyclic; Glioma; GTP-Binding Proteins; Hybrid Cells; Naphthalenes; Neuroblastoma; Okadaic Acid; Phorbols; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Endothelin mobilizes calcium and enhances glucose uptake in cultured human skeletal myoblasts and L6 myotubes.
Topics: Animals; Calcium; Cells, Cultured; Deoxyglucose; Drug Combinations; Endothelins; Female; Glucose; Humans; Insulin; Male; Muscles; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1994 |
Phorbol ester induced rapid attachment and spreading of melanoma cells and the role of extracellular matrix proteins.
Topics: Amino Acid Sequence; Cell Adhesion; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Humans; Integrins; Melanoma; Molecular Sequence Data; Naphthalenes; Oligopeptides; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Calphostin C, a potent and specific inhibitor of protein kinase C, reduces phorbol ester-induced but not primary Ca(2+)-induced catecholamine secretion from digitonin-permeabilized bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Cell Membrane Permeability; Digitonin; Drug Interactions; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Thrombin-induced increase of F-actin in human umbilical vein endothelial cells.
Topics: Actins; Alkaloids; Calcium; Capillary Permeability; Cells, Cultured; Cytoskeleton; Diterpenes; Endothelium, Vascular; Humans; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 1994 |
Evidence that protein kinase C activities involved in regulating neurite growth are localized to distal neurites.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antibodies; Benzophenanthridines; Calcium; Cells, Cultured; Isoquinolines; Naphthalenes; Nerve Growth Factors; Neurites; Phenanthridines; Phosphorylation; Piperazines; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate | 1994 |
Protein kinase C activation inhibits cytokine-induced nitric oxide synthesis in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Animals; Base Sequence; Cells, Cultured; Cytokines; Down-Regulation; Enzyme Activation; Gene Expression; Molecular Sequence Data; Muscle, Smooth, Vascular; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Polycyclic Compounds; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1994 |
Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Binding Sites; Blotting, Northern; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Gene Expression; Isoquinolines; Kinetics; Molecular Sequence Data; Naphthalenes; Nerve Growth Factors; Neuropeptide Y; Oligodeoxyribonucleotides; PC12 Cells; Piperazines; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Export of protein from the endoplasmic reticulum is regulated by a diacylglycerol/phorbol ester binding protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Biological Transport; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Compartmentation; CHO Cells; Conserved Sequence; Cricetinae; Diglycerides; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Golgi Apparatus; Membrane Glycoproteins; Mice; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rats; Receptors, Drug; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus; Viral Envelope Proteins | 1994 |
PKC and high glucose stimulate collagen alpha 1 (IV) transcriptional activity in a reporter mesangial cell line.
Topics: Alkaloids; Analysis of Variance; Animals; Cell Line; Cell Line, Transformed; Collagen; Enzyme Activation; Gene Expression; Glomerular Mesangium; Glucose; Kinetics; Luciferases; Mannitol; Mice; Mice, Inbred Strains; Naphthalenes; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1994 |
Interleukin-1 enhances beta-responsiveness of cardiac L-type calcium current suppressed by acidosis.
Topics: Acidosis; Alkaloids; Amiloride; Animals; Calcium Channels; Cells, Cultured; Guinea Pigs; Heart; Heart Ventricles; Humans; Interleukin-1; Isoproterenol; Kinetics; Male; Membrane Potentials; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Recombinant Proteins; Sodium; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin | 1994 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Alkaloids; Arachidonate 12-Lipoxygenase; Carcinoma, Squamous Cell; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Humans; Naphthalenes; Phosphatidylinositol Phosphates; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Possible role of protein kinase C-epsilon isoenzyme in inhibition of interleukin 1 beta induction of nitric oxide synthase in rat renal mesangial cells.
Topics: Amino Acid Oxidoreductases; Animals; Blotting, Northern; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Induction; Glomerular Mesangium; Interleukin-1; Isoenzymes; NADH Dehydrogenase; Naphthalenes; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Polycyclic Compounds; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Sequential activation of Raf-1 kinase, mitogen-activated protein (MAP) kinase kinase, MAP kinase, and S6 kinase by hyperosmolality in renal cells.
Topics: Amino Acid Sequence; Animals; Benzoquinones; Cells, Cultured; Dogs; Enzyme Activation; Genistein; Inositol 1,4,5-Trisphosphate; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Naphthalenes; Osmolar Concentration; Phosphorylation; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinones; Ribosomal Protein S6 Kinases; Rifabutin; Tetradecanoylphorbol Acetate | 1994 |
Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase requires protein kinase C activation.
Topics: Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Lipoprotein Lipase; Macrophages; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Naphthalenes; Polycyclic Compounds; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels.
Topics: Acetylcholine; Animals; Capillaries; Cells, Cultured; Cerebrovascular Circulation; Cycloheximide; Endothelium, Vascular; Isoflurophate; Naphthalenes; Nerve Tissue Proteins; Neurons; Polycyclic Compounds; Protein Kinase C; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
Deletion analysis of protein kinase C inactivation by calphostin C.
Topics: Animals; Base Sequence; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cattle; Humans; Isoenzymes; Molecular Sequence Data; Naphthalenes; Phosphatidylserines; Polycyclic Compounds; Protein Kinase C; Receptors, Drug; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Deletion; Spodoptera; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1995 |
Role of protein kinase C in hepatic erythropoietin synthesis.
Topics: Erythropoietin; Humans; Liver; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Insulin potentiates norepinephrine-induced vascular tone by activation of protein kinase C and tyrosine kinase.
Topics: Animals; Calcium; Drug Synergism; Genistein; Histamine; In Vitro Techniques; Insulin; Isoflavones; Male; Naphthalenes; Norepinephrine; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1994 |
Phosphopeptide mapping of cholecystokinin receptors on agonist-stimulated native pancreatic acinar cells.
Topics: Adenosine Triphosphate; Alkaloids; Amino Acid Sequence; Animals; Carbachol; Cell Membrane; Cholecystokinin; Cyanogen Bromide; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Male; Molecular Sequence Data; Naphthalenes; Pancreas; Peptide Mapping; Phosphopeptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Structure, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles | 1995 |
Protein kinase C inhibitor calphostin C prevents cytokine-induced angiogenesis in the rat.
Topics: Animals; Cytokines; Fibroblast Growth Factor 2; Interleukin-1; Male; Naphthalenes; Neovascularization, Pathologic; Polycyclic Compounds; Prostheses and Implants; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.
Topics: Adult; Alkaloids; Analog-Digital Conversion; Biological Transport; Bucladesine; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Erythroid Precursor Cells; Erythropoietin; Genistein; Humans; Image Processing, Computer-Assisted; Indoles; Intercellular Signaling Peptides and Proteins; Intracellular Fluid; Isoflavones; Isoquinolines; Naphthalenes; Peptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Videotape Recording; Wasp Venoms | 1994 |
Protein kinase C modulates calcium channels in isolated presynaptic nerve terminals of rat hippocampus.
Topics: Animals; Calcium; Calcium Channels; Fura-2; Hippocampus; Kinetics; Naphthalenes; Phorbol Esters; Phosphorylation; Polycyclic Compounds; Potassium; Presynaptic Terminals; Protein Kinase C; Rats; Sodium; Spectrometry, Fluorescence; Sphingosine; Tetradecanoylphorbol Acetate | 1995 |
Protein kinase C and phospholipase D activation in rat parotid glands.
Topics: Alkaloids; Animals; Benzophenanthridines; Enzyme Activation; Glycerophospholipids; Male; Naphthalenes; Parotid Gland; Phenanthridines; Phosphatidic Acids; Phospholipase D; Polycyclic Compounds; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells.
Topics: Base Sequence; Hematopoietic Cell Growth Factors; Molecular Sequence Data; Naphthalenes; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polycyclic Compounds; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Signal Transduction; Stem Cell Factor; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Herbimycin A inhibits phorbol ester-induced morphologic changes, adhesion, and megakaryocytic differentiation of the leukemia cell line, MEG-01.
Topics: Benzoquinones; Cell Adhesion; Cell Differentiation; Genes, fos; Genes, jun; Humans; Lactams, Macrocyclic; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Naphthalenes; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Lack of involvement of protein kinase C in ethanol-induced inhibition of metabotropic-glutamate receptor function in primary cultures of astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Cells, Cultured; Enzyme Activation; Ethanol; Female; Naphthalenes; Polycyclic Compounds; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Alpha v beta 5 integrin receptor-mediated endocytosis of vitronectin is protein kinase C-dependent.
Topics: Biological Transport; Cells, Cultured; Endocytosis; Fibroblasts; Glycoproteins; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Humans; Integrins; Naphthalenes; Oligopeptides; Protein Kinase C; Proteoglycans; Receptors, Vitronectin; Signal Transduction; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Vitronectin | 1995 |
Phorbol ester potentiation of canine pulmonary vasoreactivity to histamine.
Topics: Alkaloids; Animals; Blood Vessels; Calcium Channel Blockers; Compliance; Dogs; Drug Synergism; Female; Histamine; In Vitro Techniques; Male; Naphthalenes; Nifedipine; Protein Kinase C; Pulmonary Circulation; Staurosporine; Tetradecanoylphorbol Acetate; Vascular Resistance | 1995 |
Thromboxane A2-stimulated phospholipase D in osteoblast-like cells: possible involvement of PKC.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Cell Line; Choline; DNA; Isoquinolines; Mice; Naphthalenes; Osteoblasts; Phospholipase D; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1995 |
Suppression of apoptosis by v-ABL protein tyrosine kinase is associated with nuclear translocation and activation of protein kinase C in an interleukin-3-dependent haemopoietic cell line.
Topics: Animals; Apoptosis; Cell Line; Cell Nucleus; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Genes, abl; Hematopoietic Stem Cells; Interleukin-3; Isoenzymes; Kinetics; Naphthalenes; Oncogene Proteins v-abl; Protein Kinase C; Protein-Tyrosine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1995 |
Signal transduction pathway of acylation stimulating protein: involvement of protein kinase C.
Topics: Blood Proteins; Cells, Cultured; Complement C3a; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Maleimides; Naphthalenes; Protein Kinase C; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Triglycerides | 1995 |
Enhancement of beta-galactosidase gene expression in rat pheochromocytoma cells by exposure to extremely low frequency magnetic fields.
Topics: Adrenal Gland Neoplasms; Animals; beta-Galactosidase; Colforsin; Dantrolene; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Magnetics; Naphthalenes; Nifedipine; PC12 Cells; Pheochromocytoma; Promoter Regions, Genetic; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Vasoactive Intestinal Peptide | 1995 |
Tumor necrosis factor-alpha inhibition of 17 alpha-hydroxylase/C17-20 lyase gene (Cyp17) expression.
Topics: Aldehyde-Lyases; Animals; Biological Transport; Cells, Cultured; Cyclic AMP; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Gene Expression; Leydig Cells; Male; Mice; Mice, Inbred Strains; Naphthalenes; Protein Kinase C; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Involvement of protein kinase C activation in alpha 2-adrenoceptor-mediated contractions of rabbit saphenous vein.
Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Brimonidine Tartrate; Calcium; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Quinoxalines; Rabbits; Receptors, Adrenergic, alpha-2; Saphenous Vein; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Pro-transforming growth factor-alpha processing in human colon carcinoma cells: role of protein kinase C.
Topics: Colonic Neoplasms; Humans; Isoenzymes; Naphthalenes; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1995 |
Temozolomide reduces the metastatic potential of Lewis lung carcinoma (3LL) in mice: role of alpha-6 integrin phosphorylation.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Adhesion; Cell Membrane; Dacarbazine; Dose-Response Relationship, Drug; Integrin alpha6; Integrins; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Phosphorylation; Protein Kinase C; Temozolomide; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Phorbol ester-induced priming of superoxide generation by phosphatidic acid-stimulated neutrophils and granule-free neutrophil cytoplasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Survival; Cell-Free System; Cytoplasmic Granules; Diglycerides; Dose-Response Relationship, Drug; Humans; Isoquinolines; Kinetics; Naphthalenes; Neutrophils; Phosphatidic Acids; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways.
Topics: Actins; Animals; Cations, Divalent; Cell Adhesion; Cytoskeleton; Dithiothreitol; Ethers, Cyclic; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Marine Toxins; Membrane Proteins; Mice; Naphthalenes; Neoplasm Proteins; Okadaic Acid; Oxazoles; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, IgG; Signal Transduction; Structure-Activity Relationship; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Interferon-tau activates protein kinase C in Madin Darby bovine kidney cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Antiviral Agents; Cattle; Cell Line; Enzyme Activation; Indoles; Interferon Type I; Isoquinolines; Kidney; Kinetics; Naphthalenes; Piperazines; Pregnancy Proteins; Protein Kinase C; Recombinant Proteins; Semliki forest virus; Sheep; Staurosporine; Tetradecanoylphorbol Acetate; Trophoblasts | 1995 |
GM-CSF triggers a rapid, glucose dependent extracellular acidification by TF-1 cells: evidence for sodium/proton antiporter and PKC mediated activation of acid production.
Topics: Benzoquinones; Bone Marrow; Bone Marrow Cells; Carrier Proteins; Cell Division; Cell Line; Ethers, Cyclic; Genistein; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1993 |
Regulation of the TNF-alpha receptor in human osteosarcoma cells: role of microtubules and of protein kinase C.
Topics: Alkaloids; Cell Membrane; Cycloheximide; Ethers, Cyclic; Humans; Kinetics; Microtubules; Naphthalenes; Okadaic Acid; Osteosarcoma; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine | 1993 |
Tumor necrosis factor increases stability of interleukin-1 mRNA by activating protein kinase C.
Topics: Alkaloids; Blotting, Western; Cycloheximide; Enzyme Activation; Humans; Interleukin-1; Kinetics; Naphthalenes; Polycyclic Compounds; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Calcitriol stimulates Na(+)-Pi cotransport in a subclone of opossum kidney cells (OK-7A) by a genomic mechanism.
Topics: Animals; Calcitriol; Clone Cells; Cycloheximide; Dactinomycin; Ion Transport; Kidney; Kinetics; Naphthalenes; Opossums; Parathyroid Hormone; Phosphates; Polycyclic Compounds; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate; Vitamin D | 1993 |
Potentiation of NMDA receptor-mediated transmission in turtle cerebellar granule cells by activation of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenylate Cyclase Toxin; Animals; Cerebellum; Colforsin; Cycloleucine; Evoked Potentials; In Vitro Techniques; Isomerism; Naphthalenes; Nitric Oxide; Pertussis Toxin; Polycyclic Compounds; Purkinje Cells; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tetradecanoylphorbol Acetate; Turtles; Virulence Factors, Bordetella | 1993 |
Suppression of cytochrome P450 Cyp1a-1 induction in murine hepatoma 1c1c7 cells by 12-O-tetradecanoylphorbol-13-acetate and inhibitors of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Isoquinolines; Liver Neoplasms, Experimental; Naphthalenes; Piperazines; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta; Dose-Response Relationship, Drug; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction | 1993 |
Role of protein kinase C in tumor necrosis factor induction of endothelial cell urokinase-type plasminogen activator.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Cells, Cultured; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Induction; Extracellular Matrix; Humans; Isoquinolines; Kinetics; Molecular Sequence Data; Molecular Weight; Naphthalenes; Oligodeoxyribonucleotides; Piperazines; Plasminogen Activator Inhibitor 1; Polycyclic Compounds; Protein Kinase C; RNA; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha; Umbilical Veins; Urokinase-Type Plasminogen Activator | 1993 |
Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C.
Topics: Catechols; Genistein; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Monocytes; Naphthalenes; Nitriles; Phosphoproteins; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tyrosine; Tyrphostins; Vanadium; Zymosan | 1993 |
Involvement of phosphoinositide turnover in ouabain inotropism.
Topics: Animals; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Myocardial Contraction; Naphthalenes; Ouabain; Papillary Muscles; Phosphatidylinositols; Polycyclic Compounds; Protein Kinase C; Rabbits; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1993 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity.
Topics: Amino Acid Sequence; Base Sequence; Carcinoma, Squamous Cell; Collagenases; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Molecular Sequence Data; Molecular Weight; Mouth Neoplasms; Naphthalenes; Neoplasm Invasiveness; Neoplasm Proteins; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tumor Cells, Cultured | 1993 |
Alpha adrenergic receptor subtypes involved in prostaglandin synthesis are coupled to Ca++ channels through a pertussis toxin-sensitive guanine nucleotide-binding protein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; GTP-Binding Proteins; In Vitro Techniques; Muscle, Smooth, Vascular; Naphthalenes; Pertussis Toxin; Phospholipases A; Phospholipases A2; Polycyclic Compounds; Prostaglandins; Rabbits; Receptors, Adrenergic, alpha; Sulfonamides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex.
Topics: ADP-Ribosylation Factors; Aluminum; Animals; Brefeldin A; Cell Membrane Permeability; Coatomer Protein; Cyclopentanes; Enzyme Activation; Fluorine; Glycosaminoglycans; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Microtubule-Associated Proteins; Naphthalenes; Phorbol Esters; Polycyclic Compounds; Protein Binding; Protein Kinase C; Rats; Receptors, IgE; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cells, Cultured; Dendrites; Female; Hippocampus; Imidazoles; Indoles; Isoquinolines; Naphthalenes; Neurites; Piperazines; Polycyclic Compounds; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Pyramidal Tracts; Pyrroles; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectin.
Topics: Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; CHO Cells; Cricetinae; Enzyme Activation; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Integrins; Naphthalenes; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Receptors, Fibronectin; Tetradecanoylphorbol Acetate; Tyrosine | 1993 |
Receptor-evoked Ca2+ mobilization in pancreatic acinar cells: evidence for a regulatory role of protein kinase C by a mechanism involving the transition of high-affinity receptors to a low-affinity state.
Topics: Alkaloids; Animals; Brain; Calcium; Carbachol; Cholecystokinin; Fura-2; Inosine Triphosphate; Naphthalenes; Pancreas; Phosphorylation; Polycyclic Compounds; Proglumide; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
EBV membrane receptor (CR2) is phosphorylated by protein kinase C (PKC) in the early stages of virus entry into lymphoblastoid cells line (Raji).
Topics: Adenosine Triphosphate; Cell Membrane; Cytosol; Fluorescent Dyes; Herpesvirus 4, Human; Humans; Ionomycin; Kinetics; Lymphoma; Membrane Fusion; Naphthalenes; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Receptors, Complement 3d; Receptors, Virus; Rhodamines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Thyroid hormones stabilize acetylcholinesterase mRNA in neuro-2A cells that overexpress the beta 1 thyroid receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholinesterase; Animals; Cell Line; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Ethers, Cyclic; Humans; Isoquinolines; Kinetics; Mice; Naphthalenes; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Thyroid Hormone; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Triiodothyronine; Tumor Cells, Cultured | 1995 |
Redistribution of fodrin in an in vitro wound healing model of the corneal epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Cornea; Cytoplasm; Egtazic Acid; Epithelial Cells; Epithelium; Isoquinolines; Membrane Proteins; Microfilament Proteins; Microscopy, Fluorescence; Naphthalenes; Piperazines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Wound Healing | 1995 |
Effects of cyclic adenosine monophosphate-dependent protein kinase and calcium-dependent protein kinase modulators on stimulated gastric acid secretion in the perfused rat stomach.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Oral; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gastric Acid; Histamine; Injections, Intravenous; Isoquinolines; Male; Naphthalenes; Pentagastrin; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate | 1995 |
Mechanism of action of epidermal growth factor-induced porcine oocyte maturation.
Topics: Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Epidermal Growth Factor; Mice; Naphthalenes; Oocytes; Oogenesis; Phorbol Esters; Swine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Induction of intercellular adhesion molecule-1 by tumor necrosis factor-alpha through the 55-kDa receptor is dependent on protein kinase C in human retinal pigment epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Carcinogens; Cell Line, Transformed; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; Isoquinolines; Naphthalenes; Pigment Epithelium of Eye; Protein Kinase C; Receptors, Tumor Necrosis Factor; Second Messenger Systems; Signal Transduction; Simian virus 40; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Protein kinase C inhibitors enhance G-protein induced phospholipase A2 activation in intact human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aluminum Compounds; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Fluorides; GTP-Binding Proteins; Humans; Isoquinolines; Kinetics; Naphthalenes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Piperazines; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1996 |
d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties.
Topics: Amino Acid Sequence; Animals; Antioxidants; Aorta; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethers, Cyclic; Flow Cytometry; Isomerism; Kinetics; Marine Toxins; Molecular Sequence Data; Muscle, Smooth, Vascular; Naphthalenes; Okadaic Acid; Oligopeptides; Oxazoles; Protein Kinase C; Rats; Substrate Specificity; Tetradecanoylphorbol Acetate; Thymidine; Vitamin E | 1995 |
Extracellular ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fc receptors.
Topics: Adenosine Triphosphate; Animals; beta-N-Acetylhexosaminidases; Calcium; Cell Line; Cross-Linking Reagents; Extracellular Space; Genistein; Histamine Release; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Isoflavones; Mast Cells; Mice; Mice, Inbred A; Mice, Inbred C57BL; Naphthalenes; Phosphorylation; Protein Kinase C; Receptors, Fc; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1996 |
Modulation by protein kinase C activation of rat brain delayed-rectifier K+ channel expressed in Xenopus oocytes.
Topics: Alkaloids; Animals; Base Sequence; Brain; Cell Membrane; Diglycerides; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Female; Kinetics; Membrane Potentials; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenes; Oocytes; Patch-Clamp Techniques; Potassium Channels; Protein Kinase C; Protein Structure, Secondary; Rats; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Xenopus laevis | 1996 |
Regulation of expression of the steroidogenic acute regulatory (StAR) protein by ACTH in bovine adrenal fasciculata cells.
Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata | 1996 |
Protein kinase C-delta mRNA is down-regulated transcriptionally and post-transcriptionally by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Northern; Cell Line; Cell Membrane; Cell Nucleus; Cytosol; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Isoenzymes; Kinetics; Lymphoma, B-Cell; Mice; Naphthalenes; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Interleukin-1beta activates protein kinase C zeta in renal mesangial cells. Potential role in prostaglandin E2 up-regulation.
Topics: Alkaloids; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cytosol; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Naphthalenes; NF-kappa B; Oligonucleotide Probes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1996 |
Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Line; Cell Nucleus; Dactinomycin; DNA Probes; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Interleukin-11; Isoflavones; Isoquinolines; Kinetics; Luciferases; Naphthalenes; Open Reading Frames; Piperazines; Primates; Protein Kinase C; Recombinant Fusion Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection | 1996 |
Investigation of the role of protein kinase C and tyrosine kinases during the rapid and sustained release of superoxide from adherent human neutrophils.
Topics: Cell Adhesion; Cinnamates; Enzyme Inhibitors; Humans; Indoles; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; Phenols; Protein Kinase C; Protein-Tyrosine Kinases; Sulfides; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Thrombin stimulates production of interleukin-8 in human umbilical vein endothelial cells.
Topics: Blotting, Northern; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Interleukin-1; Interleukin-8; Isoflurophate; Naphthalenes; Peptide Fragments; Protein Kinase C; Receptors, Thrombin; RNA, Messenger; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1996 |
24,25(OH)2 vitamin D3 modulates the L-type Ca2+ channel current in UMR 106 cells: involvement of protein kinase A and protein kinase C.
Topics: 24,25-Dihydroxyvitamin D 3; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; Naphthalenes; Osteoblasts; Osteosarcoma; Patch-Clamp Techniques; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Effects of calphostin C, specific PKC inhibitor on TPA-induced normal human melanocyte growth, morphology and adhesion.
Topics: Cell Adhesion; Cell Division; Cells, Cultured; Enzyme Inhibitors; Humans; Melanocytes; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase C modulates cytosolic free calcium by stimulating calcium pump activity in Jurkat T cells.
Topics: Alkaloids; Calcium; Calcium-Transporting ATPases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Ionophores; Lanthanum; Leukemia; Naphthalenes; Phorbol Esters; Protein Kinase C; Sodium; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Role of the NHE3 isoform of the Na+/H+ exchanger in sodium absorption by the rabbit gallbladder.
Topics: Absorption; Amiloride; Animals; Base Sequence; Body Water; DNA, Complementary; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gallbladder; Molecular Sequence Data; Naphthalenes; Polymerase Chain Reaction; Rabbits; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1996 |
Role of tumor necrosis factor-alpha on mesangial cell MCP-1 expression and monocyte migration: mechanisms mediated by signal transduction.
Topics: Animals; Biomechanical Phenomena; Bucladesine; Chemokine CCL2; Chemotaxis, Leukocyte; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Glomerular Mesangium; Mice; Mice, Transgenic; Monocytes; Naphthalenes; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Multiple signaling pathways control the activation of the CEF-4/9E3 cytokine gene by pp60v-src.
Topics: Animals; Avian Proteins; Avian Sarcoma Viruses; Blotting, Northern; Cell Transformation, Viral; Chick Embryo; Cytokines; DNA-Binding Proteins; Gene Expression Regulation; Kinetics; Naphthalenes; Nuclear Proteins; Oncogene Protein pp60(v-src); Promoter Regions, Genetic; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Regulatory Factor X Transcription Factors; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 1996 |
DNA binding by cut homeodomain proteins is down-modulated by protein kinase C.
Topics: Animals; Cell Line; Cloning, Molecular; DNA; Drosophila Proteins; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Homeodomain Proteins; Humans; Naphthalenes; Nerve Tissue Proteins; Nuclear Proteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Repetitive Sequences, Nucleic Acid; Repressor Proteins; Tetradecanoylphorbol Acetate; Transcription Factors | 1996 |
Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells: protein kinase C, but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arachidonic Acid; Calcium Channel Agonists; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Male; Microspheres; Naphthalenes; Pituitary Gland; Potassium; Protein Kinase C; Salmon; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Galpha12 and galpha13 are phosphorylated during platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; COS Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Naphthalenes; Phosphorylation; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Calphostin C induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in a pathway independent of tumor promoter phorbol ester-mediated down-regulation of protein kinase C.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Down-Regulation; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Naphthalenes; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1996 |
Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells.
Topics: Antigens, CD; Bronchi; Carcinoma, Mucoepidermoid; Cell Line; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Epithelium; Gene Expression; Humans; Interleukin-1; Naphthalenes; Protein Kinase C; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Respiratory System; RNA, Messenger; Tetradecanoylphorbol Acetate; Trachea; Tumor Cells, Cultured | 1996 |
Calphostin C-sensitive enhancements of force by lysophosphatidylinositol and diacylglycerols in mesenteric arteries from the rat.
Topics: Animals; Calcium; Diglycerides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Lysophospholipids; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Norepinephrine; Permeability; Protein Kinase C; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1996 |
Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity.
Topics: Cell Differentiation; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Naphthalenes; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Molecular Sequence Data; Naphthalenes; Nitriles; Nitrophenols; Nuclear Envelope; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrphostins | 1996 |
The activation of phospholipase D participates in the mitogenic action of arginine vasopressin in cultured rat glomerular mesangial cells.
Topics: 2,3-Diphosphoglycerate; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diphosphoglyceric Acids; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Glycerophospholipids; Male; Mitogens; Naphthalenes; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Soluble tumor necrosis factor receptors are present in human vitreous and shed by retinal pigment epithelial cells.
Topics: Aged; Aged, 80 and over; Cells, Cultured; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Naphthalenes; Pigment Epithelium of Eye; Protein Kinase C; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Vitreous Body | 1996 |
Hypoxia-induced pulmonary arterial contraction appears to be dependent on myosin light chain phosphorylation.
Topics: Angiotensin II; Animals; Azepines; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Naphthalenes; Phenylephrine; Phosphorylation; Potassium Chloride; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Protein kinase C stimulates the small-conductance K+ channel in the basolateral membrane of the CCD.
Topics: Animals; Cyclic GMP; Electric Conductivity; Enzyme Inhibitors; In Vitro Techniques; Kidney Tubules, Collecting; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Patch-Clamp Techniques; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Stimulation of Ca2+ current by phorbol esters in rat myometrial cells is dependent on intracellular Ca2+ concentration.
Topics: Animals; Calcium; Calcium Channels; Female; Membrane Potentials; Myometrium; Naphthalenes; Osmolar Concentration; Patch-Clamp Techniques; Phosphorylation; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Effects of three different Ca(2+)-ATPase inhibitors on Ca2+ response and leukotriene release in RBL-2H3 cells.
Topics: Animals; Basophils; Calcium; Calcium-Transporting ATPases; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroquinones; Indoles; Leukemia, Basophilic, Acute; Leukotriene C4; Lipoxygenase Inhibitors; Mice; Naphthalenes; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1996 |
Inhibition of protein kinase C-dependent noradrenaline release by wortmannin in PC12 cells.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Calcium; Enzyme Inhibitors; Intercellular Signaling Peptides and Proteins; Naphthalenes; Norepinephrine; PC12 Cells; Peptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Potassium; Protein Kinase C; Rats; Secretory Rate; Tetradecanoylphorbol Acetate; Wasp Venoms; Wortmannin | 1997 |
Phorbol ester enhancement of IL-3-dependent proliferation of primitive hematopoietic progenitors of mice in culture.
Topics: Animals; Bone Marrow; Cell Division; Cells, Cultured; Fluorouracil; Genistein; Hematopoietic Stem Cells; Interleukin-3; Isoflavones; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: activation of protein kinase C at dusk and dawn.
Topics: Alkaloids; Animals; Benzophenanthridines; Circadian Rhythm; Enzyme Activation; Enzyme Inhibitors; Male; Melatonin; Naphthalenes; Pertussis Toxin; Phenanthridines; Protein Kinase C; Rats; Signal Transduction; Suprachiasmatic Nucleus; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1997 |
Involvement of protein kinase C in nerve growth factor- and K-252a-stimulated calcium uptake into PC12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Agonists; Carbazoles; Carcinogens; Enzyme Inhibitors; Indole Alkaloids; Indoles; Isoenzymes; Naphthalenes; Nerve Growth Factors; PC12 Cells; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Rats; Receptors, Nerve Growth Factor; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillin.
Topics: Binding Sites; Calcimycin; Cell Adhesion Molecules; Cell Line; Cytochalasin D; Cytoskeletal Proteins; Egtazic Acid; Humans; Megakaryocytes; Naphthalenes; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proline; Protein-Tyrosine Kinases; Proteins; Recombinant Fusion Proteins; Signal Transduction; Stem Cell Factor; Tetradecanoylphorbol Acetate; TYK2 Kinase | 1997 |
Differential desensitization of thromboxane A2 receptor subtypes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Naphthalenes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1997 |
Prostaglandin F2alpha stimulates interleukin-6 synthesis via activation of PKC in osteoblast-like cells.
Topics: Animals; Cell Line; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Interleukin-6; Mice; Naphthalenes; Osteoblasts; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Differential regulation by protein kinase C isoforms of nitric oxide synthase induction in RAW 264.7 macrophages and rat aortic smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Kinetics; Lipopolysaccharides; Macrophages; Mice; Muscle, Smooth, Vascular; Naphthalenes; Nitric Oxide Synthase; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Contribution of PKC to beta-hexosaminidase-induced airway smooth muscle proliferation.
Topics: Animals; beta-N-Acetylhexosaminidases; Cattle; Cell Count; Cell Division; Diacylglycerol Kinase; Enzyme Inhibitors; Hexosaminidase A; Insulin; Muscle, Smooth; Naphthalenes; Phenylisopropyladenosine; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Pyrimidinones; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Thymidine; Trachea | 1997 |
Phorbol 12-myristate 13-acetate (PMA)-induced oxyradical production in rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Calcium; Carcinogens; Catalase; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Knee Joint; Luminescent Measurements; Macrophages; Naphthalenes; Photons; Protein Kinase C; Superoxide Dismutase; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate | 1997 |
Evidence that protein kinase C is involved in delta-aminolevulinate synthase expression in rat hepatocytes.
Topics: 5-Aminolevulinate Synthetase; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Diglycerides; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Naphthalenes; Phenobarbital; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Bombesin-stimulated ceramide production and MAP kinase activation in rabbit rectosigmoid smooth muscle cells.
Topics: Anal Canal; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Ceramides; Chromatography, High Pressure Liquid; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Kinetics; Muscle Contraction; Muscle, Smooth; Naphthalenes; Protein Kinase C; Rabbits; Sphingomyelins; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Effects of interferon and PKC modulators on human glioma protein kinase C, cell proliferation, and cell cycle.
Topics: Antineoplastic Agents; Cell Cycle; Cell Division; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Inhibitors; Glioma; Humans; Interferon alpha-2; Interferon-alpha; Naphthalenes; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Protein kinase C activation during progesterone-stimulated acrosomal exocytosis in human spermatozoa.
Topics: Acrosome; Alkaloids; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Humans; In Vitro Techniques; Male; Naphthalenes; Nifedipine; Phenanthridines; Phosphorylation; Progesterone; Protein Kinase C; Signal Transduction; Sperm Capacitation; Spermatozoa; Tetradecanoylphorbol Acetate | 1996 |
Regulation of heparin-binding EGF-like growth factor expression by phorbol ester in a human hepatoma-derived cell line.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Hepatocellular; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Naphthalenes; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Myogenic constriction of human coronary arterioles.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Arterioles; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Cardiopulmonary Bypass; Child; Child, Preschool; Coronary Vessels; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Infant; Infant, Newborn; Middle Aged; Muscle Tonus; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Regression Analysis; Tetradecanoylphorbol Acetate; Vascular Resistance; Vasoconstriction | 1997 |
Enhanced synthesis of proteoglycans by vascular endothelial cells treated with phorbol ester.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; Cycloheximide; Dactinomycin; Electrophoresis, Gel, Pulsed-Field; Endothelium, Vascular; Enzyme Activation; Leucine; Naphthalenes; Protein Kinase C; Proteoglycans; Tetradecanoylphorbol Acetate | 1997 |
Phorbol esters stimulate muscle glucose transport by a mechanism distinct from the insulin and hypoxia pathways.
Topics: Animals; Biological Transport; Enzyme Activation; Enzyme Inhibitors; Glucose; Glucose Transporter Type 4; Hypoxia; Intracellular Signaling Peptides and Proteins; Inulin; Isoenzymes; Kinetics; Male; Membrane Proteins; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; Phorbol Esters; Protein Kinase C; Proteins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C is required for induction of 2',5'-oligoadenylate synthetases.
Topics: 2',5'-Oligoadenylate Synthetase; Alkaloids; Benzophenanthridines; Burkitt Lymphoma; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Interferon-alpha; Isoenzymes; Naphthalenes; Phenanthridines; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Activation of phospholipase D in FRTL-5 thyroid cells by forskolin and dibutyryl-cyclic adenosine monophosphate.
Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Calcium; Cell Line; Colforsin; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Humans; Naphthalenes; Phenanthridines; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1997 |
A factor with a zinc- and phorbol ester-binding domain is necessary for endosome fusion.
Topics: Alkaloids; Animals; Benzophenanthridines; Binding Sites; Cell Line; Cysteine; Endosomes; Enzyme Inhibitors; Isoenzymes; Kinetics; Macrophages; Membrane Fusion; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Recombinant Fusion Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Zinc | 1997 |
Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cytosol; Enzyme Inhibitors; Homeostasis; Isoproterenol; Kinetics; Microglia; Naphthalenes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Stimulation of brook trout ovarian steroidogenesis by gonadotropins I and II is mediated by the cyclic adenosine 3',5'-monophosphate/protein kinase A pathway.
Topics: Animals; Calcimycin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Female; Gonadotropins, Pituitary; Hydroxyprogesterones; Ionophores; Naphthalenes; Ovarian Follicle; Ovary; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trout | 1997 |
The role of protein kinase C in GH secretion induced by GH-releasing factor and GH-releasing peptides in cultured ovine somatotrophs.
Topics: Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cell Membrane; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Hormone; Growth Hormone-Releasing Hormone; Isoquinolines; Naphthalenes; Oligopeptides; Phenanthridines; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Sheep; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin.
Topics: Amino Acid Sequence; beta Catenin; Consensus Sequence; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Indoles; Maleimides; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Point Mutation; Protein Kinase C; Protein Processing, Post-Translational; Sequence Alignment; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Trans-Activators; Ubiquitins | 1997 |
Complex shape changes in isolated rat osteoclasts: involvement of protein kinase C in the response to calcitonin.
Topics: Analgesics; Animals; Calcitonin; Carcinogens; Cell Separation; Cell Size; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Naphthalenes; Osteoclasts; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Isoform specificity of activators and inhibitors of protein kinase C gamma and delta.
Topics: Acetophenones; Alkaloids; Benzophenanthridines; Benzopyrans; Bryostatins; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Lactones; Macrolides; Maleimides; Naphthalenes; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; Recombinant Proteins; Schizosaccharomyces; Sphingosine; Tetradecanoylphorbol Acetate; Transformation, Genetic | 1997 |
PKC regulation of microfilament network organization in keratinocytes defined by a pharmacological study with PKC activators and inhibitors.
Topics: Actin Cytoskeleton; Actins; Carcinogens; Cell Adhesion; Cell Movement; Cell Polarity; Cell Size; Cells, Cultured; Collagen; Enzyme Activation; Enzyme Inhibitors; Growth Substances; Humans; Keratinocytes; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Skin; Stress, Physiological; Tetradecanoylphorbol Acetate | 1997 |
Calphostin C synergistically induces apoptosis with VP-16 in lymphoma cells which express abundant phosphorylated Bcl-2 protein.
Topics: Apoptosis; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; DNA Fragmentation; Drug Synergism; Etoposide; Humans; Lymphoma; Naphthalenes; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tumor Cells, Cultured; Up-Regulation | 1997 |
The mineralocorticoid aldosterone activates a proton conductance in cultured kidney cells.
Topics: Aldosterone; Animals; Anti-Bacterial Agents; Cell Line; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Imidazoles; Kidney; Kinetics; Macrolides; Meglumine; Membrane Potentials; Naphthalenes; Pertussis Toxin; Protein Kinase C; Protein Serine-Threonine Kinases; Proton Pump Inhibitors; Proton-Translocating ATPases; Sodium-Hydrogen Exchangers; Spironolactone; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Zinc | 1997 |
Modulatory effects of PKC activity on increased 92-kDa gelatinase secretion by neonatal alveolar macrophages.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Concanavalin A; Cyclic AMP; Cysteine Endopeptidases; Enzyme Inhibitors; Gelatinases; Gene Expression Regulation, Enzymologic; Kinetics; Macrophages, Alveolar; Molecular Weight; Naphthalenes; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Stimulation of protein kinase C activity by tumor necrosis factor-alpha in bovine bronchial epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bronchi; Cattle; Cell Movement; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Fibronectins; Isoenzymes; Kinetics; Naphthalenes; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Integrin-mediated activation of mitogen-activated protein kinase is independent of the activation of protein kinase C epsilon during the spreading of HeLa cells on a gelatin substratum.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Contact Inhibition; Culture Media, Serum-Free; Down-Regulation; Enzyme Activation; Gelatin; HeLa Cells; Humans; Integrins; Isoenzymes; Naphthalenes; Protein Kinase C; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate | 1997 |
Phorbol ester-induced low density lipoprotein receptor gene expression in HepG2 cells involves protein kinase C-mediated p42/44 MAP kinase activation.
Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Flavonoids; Gene Expression Regulation; Humans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Polymerase Chain Reaction; Protein Kinase C; Receptors, LDL; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Suppression of GnRH gene expression in GT1-1 hypothalamic neuronal cells: action of protein kinase C.
Topics: Animals; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Gonadotropin-Releasing Hormone; Hypothalamus; Isoenzymes; Luciferases; Mice; Naphthalenes; Neurons; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-alpha; Proto-Oncogene Proteins c-fos; Recombinant Fusion Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1997 |
Enhancement of secretagogue-induced adrenocorticotropic hormone release from cultured sheep anterior pituitary cells by recombinant ovine interleukin 1.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cells, Cultured; Corticotropin-Releasing Hormone; Drug Interactions; Enzyme Inhibitors; Interleukin-1; Male; Naphthalenes; Orchiectomy; Pituitary Gland, Anterior; Protein Kinase C; Recombinant Proteins; Sheep; Tetradecanoylphorbol Acetate | 1998 |
Positive and negative controls by protein kinases of sodium-dependent Ca2+ efflux from cultured bovine adrenal chromaffin cells stimulated by lysophosphatidic acid.
Topics: Adrenal Glands; Animals; Calcium; Carbachol; Catecholamines; Cattle; Chromaffin Cells; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Genistein; Lysophospholipids; Naphthalenes; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Sodium; Sodium-Calcium Exchanger; Staurosporine; Structure-Activity Relationship; Suramin; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1998 |
Assay to determine the isoform specificity of protein kinase C inhibitors.
Topics: Alkaloids; Animals; Benzophenanthridines; Cloning, Molecular; Enzyme Inhibitors; Isoenzymes; Kinetics; Mammals; Naphthalenes; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; Recombinant Proteins; Schizosaccharomyces; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices.
Topics: Alkaloids; Amphetamine; Animals; Benzophenanthridines; Biological Transport; Calcium; Corpus Striatum; Dopamine; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Naphthalenes; Phenanthridines; Protein Kinase C; Rats; Reserpine; Tetradecanoylphorbol Acetate | 1998 |
Contribution of protein kinase C to p53-dependent WAF1 induction pathway after heat treatment in human glioblastoma cell lines.
Topics: Amino Acid Sequence; Cell Extracts; Cell Line, Transformed; Cell Nucleus; Consensus Sequence; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Enzyme Activation; Enzyme Inhibitors; Glioblastoma; Hot Temperature; Humans; Mutation; Naphthalenes; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells.
Topics: Binding, Competitive; Cell Adhesion; DNA-Binding Proteins; Enzyme Inhibitors; Fibronectins; Humans; I-kappa B Proteins; Integrin alpha4beta1; Integrins; Jurkat Cells; Lymphocyte Activation; Naphthalenes; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Kinase C; Receptors, Fibronectin; Receptors, Lymphocyte Homing; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1998 |
Gap junction Cx26 gene modulation by phorbol esters in benign and malignant human mammary cells.
Topics: Base Sequence; Breast; Breast Neoplasms; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Connexin 26; Connexins; Deoxyribonuclease I; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Molecular Sequence Data; Naphthalenes; Protein Biosynthesis; Protein Kinase C; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Extracellular signal-regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis.
Topics: Anisomycin; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Establishment of a human leukemia HL-60 cell line that expresses high levels of M-CSF receptors.
Topics: Apoptosis; Cell Differentiation; Cell Division; fas Receptor; HL-60 Cells; Humans; Macrophage Colony-Stimulating Factor; Mitogens; Naphthalenes; Protein Kinase C; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1998 |
Enhanced NOR-1 gene expression by exposure of Chinese hamster cells to high-density 50 Hz magnetic fields.
Topics: Animals; Calcium Channel Blockers; Carotenoids; CHO Cells; Colforsin; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Magnetics; Naphthalenes; Nerve Tissue Proteins; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Vitamin A | 1998 |
Novel protein kinase C, nPKC, inhibition of murine bumetanide-sensitive Na+,K+,2Cl- cotransporter BSC1 in Xenopus oocyte.
Topics: Animals; Bumetanide; Carrier Proteins; Enzyme Activation; Enzyme Inhibitors; Female; Gene Transfer Techniques; Mice; Naphthalenes; Oocytes; Protein Kinase C; Recombinant Proteins; Rubidium; Sodium-Potassium-Chloride Symporters; Staurosporine; Tetradecanoylphorbol Acetate; Xenopus | 1998 |
High glucose induces alteration of gap junction permeability and phosphorylation of connexin-43 in cultured aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Cattle; Cell Communication; Cells, Cultured; Connexin 43; Dose-Response Relationship, Drug; Enzyme Activation; Gap Junctions; Glucose; Mannitol; Muscle, Smooth, Vascular; Naphthalenes; Phosphorylation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
A high glucose concentration stimulates the expression of monocyte chemotactic peptide 1 in human mesangial cells.
Topics: Cells, Cultured; Chemokine CCL2; Diabetic Neuropathies; Enzyme Inhibitors; Gene Expression Regulation; Glomerular Mesangium; Glucose; Humans; Monocytes; Naphthalenes; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Role of protein kinases in regulation of apical secretion and basal-lateral membrane recycling traffic in reconstituted rabbit lacrimal gland acini.
Topics: Animals; beta-N-Acetylhexosaminidases; Calcimycin; Carbachol; Cells, Cultured; Endocytosis; Enzyme Inhibitors; Eye Proteins; Female; Homeostasis; Lacrimal Apparatus; Naphthalenes; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1998 |
Staurosporine-induced versus spontaneous squamous metaplasia in pre- and postmenopausal breast tissue.
Topics: Adult; Aged; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Keratin-10; Keratinocytes; Keratins; Middle Aged; Naphthalenes; Postmenopause; Premenopause; Protein Kinase C; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Thrombomodulin; Tumor Cells, Cultured; Up-Regulation | 1998 |
Platelet-derived growth factor-induced disruption of gap junctional communication and phosphorylation of connexin43 involves protein kinase C and mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Communication; Connexin 43; Enzyme Inhibitors; Epithelial Cells; Gap Junctions; Liver; Naphthalenes; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Protein kinase C mediates the signal for interferon-gamma mRNA expression in cytotoxic T cells after their adhesion to laminin.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Blotting, Western; Cell Adhesion; Cell Line; Extracellular Matrix Proteins; Integrin alpha6; Integrin alpha6beta1; Integrins; Interferon-gamma; Laminin; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Naphthalenes; Polymerase Chain Reaction; Protein Kinase C; Receptors, Laminin; RNA, Messenger; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Arginine vasopressin inhibition of cytochrome P450c17 and testosterone production in mouse Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Cells, Cultured; Enzyme Inhibitors; Interleukin-1; Intracellular Signaling Peptides and Proteins; Leydig Cells; Male; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; Phosphorylation; Proteins; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Testosterone; Tetradecanoylphorbol Acetate | 1998 |
Transforming growth factor-beta2 regulates C3 secretion in monocytes through a protein kinase C-dependent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Complement C3; Drug Interactions; Humans; Inflammation; Isoenzymes; Isoquinolines; Monocytes; Naphthalenes; Protein Kinase C; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1998 |
Expression of protein kinase C isozymes in human basophils: regulation by physiological and nonphysiological stimuli.
Topics: Antibodies, Anti-Idiotypic; Basophils; Biological Transport; Calcium; Carbazoles; Cell Membrane; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Histamine Release; Humans; Indoles; Ionomycin; Ionophores; Isoenzymes; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Calphostin C induces selective disassembly of the Golgi complex by a protein kinase C-independent mechanism.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cattle; Cell Line; Chimerin 1; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Golgi Apparatus; In Vitro Techniques; Light; Microscopy, Electron; Naphthalenes; Nerve Tissue Proteins; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1998 |
Antioxidants stimulate transcriptional activation of the c-fos gene by multiple pathways in human fetal lung fibroblasts (WI-38).
Topics: Acetylcysteine; Antioxidants; Blotting, Northern; Carcinogens; Chromans; Enzyme Inhibitors; Fetus; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation; Glutathione; Humans; Lung; Masoprocol; Naphthalenes; Protein Kinase C; Proto-Oncogene Proteins c-fos; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1998 |
Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutation; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; ras Proteins; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate | 1998 |
Evidence that protein kinase Cepsilon mediates phorbol ester inhibition of calphostin C- and tumor necrosis factor-alpha-induced apoptosis in U937 histiocytic lymphoma cells.
Topics: Apoptosis; Chromatin; DNA Fragmentation; Enzyme Inhibitors; Humans; Isoenzymes; Kinetics; Lymphoma, Large B-Cell, Diffuse; Naphthalenes; Nucleosomes; Peptide Fragments; Protein Kinase C; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Differential effects of two protein kinase C inhibitors, calphostin C and Gö6976, on pineal cyclic nucleotide accumulation.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbazoles; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoproterenol; Male; Naphthalenes; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Pineal Gland; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Activation of H+-ATPase by hypotonicity: a novel regulatory mechanism for H+ secretion in IMCD cells.
Topics: Ammonium Chloride; Animals; Cell Line; Cells, Cultured; Enzyme Activation; Fluoresceins; Hydrogen-Ion Concentration; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Naphthalenes; Osmolar Concentration; Protein Kinase C; Proton-Translocating ATPases; Staurosporine; Tetradecanoylphorbol Acetate; Tetraethylammonium | 1998 |
HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation.
Topics: Antigens, Surface; Apoptosis; Cell Death; Clone Cells; Cyclosporine; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression Regulation; HIV Envelope Protein gp120; Humans; Ionomycin; Kinetics; Lymphocyte Activation; Membrane Glycoproteins; Naphthalenes; Protein Kinase C; Receptors, Antigen, T-Cell; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Th1 Cells | 1998 |
Protein kinase C plays no role in KCl-induced vascular contraction in Ca(2+)-free medium.
Topics: Animals; Aorta, Thoracic; Calcium; Enzyme Inhibitors; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Potassium Chloride; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Effects of genistein and staurosporine on angiotensin II-induced DNA synthesis, protein synthesis and mitogen-activated protein kinase activation in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Genistein; In Vitro Techniques; Male; Muscle Proteins; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1998 |
A potential role of Ras-mediated signal transduction for the enhancement of depolarization-induced Ca2+ responses in hippocampal neurons by basic fibroblast growth factor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Antimanic Agents; Calcium; Calcium Channels; Calcium Channels, N-Type; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Inhibitors; Estrenes; Fibroblast Growth Factor 2; Hippocampus; Lithium Chloride; Membrane Potentials; Naphthalenes; Neurons; Phosphodiesterase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyrrolidinones; ras Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 1998 |
Ca(2+)-dependent enhancement of [3H]noradrenaline uptake in PC12 cells through calmodulin-dependent kinases.
Topics: Actins; Amino Acid Sequence; Androstadienes; Animals; Biological Transport; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carcinogens; Carrier Proteins; Cytochalasin D; Desipramine; Dopamine; Enzyme Inhibitors; Marine Toxins; Molecular Sequence Data; Myosin Light Chains; Naphthalenes; Neurons; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleic Acid Synthesis Inhibitors; Oxazoles; PC12 Cells; Peptide Fragments; Phosphorylation; Rats; Sympathomimetics; Symporters; Tetradecanoylphorbol Acetate; Tritium; Wortmannin | 1998 |
PKC and tyrosine kinase involvement in amyloid beta (25-35)-induced chemotaxis of microglia.
Topics: Alkaloids; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzophenanthridines; Benzoquinones; Brain; Carcinogens; Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lactams, Macrocyclic; Microglia; Naphthalenes; Peptide Fragments; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Wistar; Rifabutin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Calphostin C induces expression of amphiregulin mRNA via reactive oxygen species in IEC-6 cells.
Topics: Acetylcysteine; Amphiregulin; Animals; Cell Line; Drug Interactions; EGF Family of Proteins; Enzyme Inhibitors; Epithelial Cells; Free Radical Scavengers; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Intestines; Naphthalenes; Rats; Reactive Oxygen Species; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Hydrogen peroxide enhances shedding of type I soluble tumor necrosis factor receptor from pulmonary epithelial cells.
Topics: Cell Line; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Free Radical Scavengers; Gene Expression; Humans; Hydrogen Peroxide; Hydroxamic Acids; Hydroxyl Radical; Lung; Metalloendopeptidases; Naphthalenes; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Receptors, Tumor Necrosis Factor; RNA, Messenger; Signal Transduction; Solubility; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Involvement of Rab4 in regulated exocytosis of rat pancreatic acini.
Topics: Amino Acid Sequence; Amylases; Animals; Calcium; Cholecystokinin; Exocytosis; Fluorescent Antibody Technique; Glucose Transporter Type 4; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Naphthalenes; Pancreas; rab4 GTP-Binding Proteins; Rats; Tetradecanoylphorbol Acetate | 1999 |
Activation of protein kinase C by phorbol esters modulates alpha2beta1 integrin on MCF-7 breast cancer cells.
Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Breast Neoplasms; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Integrins; Mice; Naphthalenes; Protein Kinase C; Rats; Receptors, Collagen; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
MAP kinase activity is downregulated by phorbol ester during mouse oocyte maturation and egg activation in vitro.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Fertilization in Vitro; Humans; Interphase; Meiosis; Metaphase; Mice; Mice, Inbred BALB C; Naphthalenes; Okadaic Acid; Oocytes; Oogenesis; Ovum; Phosphoprotein Phosphatases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1999 |
Involvement of p42/p44 MAP kinase in endothelin-1-induced interleukin-6 synthesis in osteoblast-like cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; Tetradecanoylphorbol Acetate | 1999 |
Regulation of L-type Ca2+ channels in rabbit portal vein by G protein alphas and betagamma subunits.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium Channels; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GTP-Binding Proteins; In Vitro Techniques; Indoles; Male; Maleimides; Models, Biological; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Portal Vein; Protein Conformation; Protein Kinase C; Pyrroles; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 1999 |
Protein kinase C alpha protein expression is necessary for sustained erythropoietin production in human hepatocellular carcinoma (Hep3B) cells exposed to hypoxia.
Topics: Cell Hypoxia; Down-Regulation; Enzyme Activation; Erythropoietin; Humans; Isoenzymes; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Phorbol ester promotes endocytosis by activating a factor involved in endosome fusion.
Topics: Alkaloids; Animals; Benzophenanthridines; Cell Line; Cell Membrane; Chelating Agents; CHO Cells; Cricetinae; Endocytosis; Endosomes; Enzyme Inhibitors; Ethylenediamines; GTP Phosphohydrolases; GTP-Binding Proteins; Membrane Fusion; Mutagenesis, Site-Directed; Naphthalenes; Phenanthridines; Protein Kinase C; rab5 GTP-Binding Proteins; Recombinant Proteins; Sindbis Virus; Tetradecanoylphorbol Acetate; Transfection; Zinc | 1999 |
Evidence on the participation of protein kinase C alpha in the proliferation of cultured myoblasts.
Topics: Animals; Cell Differentiation; Cell Division; Chick Embryo; DNA Replication; Indoles; Isoenzymes; Maleimides; Muscle, Skeletal; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate | 1999 |
Possible involvement of atypical protein kinase C (PKC) in glucose-sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive
Topics: Animals; Carbazoles; Cell Line; DNA; Enzyme Inhibitors; Gene Expression; Glucose; Homeodomain Proteins; Humans; Indoles; Insulin; Islets of Langerhans; Mice; Naphthalenes; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription, Genetic; Transfection | 1999 |
The role of protein kinase C isozymes in bombesin-stimulated gastrin release from human antral gastrin cells.
Topics: Adult; Biological Transport; Bombesin; Carbazoles; Female; Gastrin-Secreting Cells; Gastrins; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Indoles; Isoenzymes; Male; Maleimides; Naphthalenes; Protein Kinase C; Pyloric Antrum; Tetradecanoylphorbol Acetate | 1999 |
Mitogen-activated protein (MAP) kinases are involved in interleukin-1 (IL-1)-induced IL-6 synthesis in osteoblasts: modulation not of p38 MAP kinase, but of p42/p44 MAP kinase by IL-1-activated protein kinase C.
Topics: Animals; Animals, Newborn; Bridged-Ring Compounds; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Imidazoles; Interleukin-1; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Norbornanes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 1999 |
TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides trea
Topics: Adenocarcinoma; Base Sequence; Carbazoles; Down-Regulation; Humans; Indoles; Isoenzymes; Naphthalenes; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Rectal Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Protein kinase c-dependent pathway is critical for the production of pro-inflammatory cytokines (TNF-alpha, IL-1beta, IL-6).
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-1; Interleukin-6; Isoenzymes; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Monocytes; Naphthalenes; Phosphorylation; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1999 |
Involvement of protein kinase C in Rickettsia rickettsii-induced transcriptional activation of the host endothelial cell.
Topics: Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Naphthalenes; NF-kappa B; Protein Kinase C; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Rickettsia rickettsii; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin; Transcriptional Activation; Umbilical Veins | 1999 |
Phorbol ester inhibits DNA damage-induced apoptosis in U937 cells through activation of protein kinase C.
Topics: Apoptosis; Blotting, Northern; Bucladesine; Calcitriol; Cell Differentiation; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Humans; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate; U937 Cells; Ultraviolet Rays | 1999 |
Relationship between intracellular Ca2+ store and protein kinase C in agonist-induced contraction of hypertensive rat aortae.
Topics: Animals; Aorta; Calcium; Carcinogens; Endothelin-1; Enzyme Inhibitors; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma; Serotonin; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
Nitric oxide activates PKCalpha and inhibits Na+-K+-ATPase in opossum kidney cells.
Topics: Alkaloids; Animals; Arachidonic Acids; Carbazoles; Cell Line; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Isoenzymes; Kidney; Kidney Tubules, Proximal; Kinetics; Naphthalenes; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Opossums; Protein Kinase C; Protein Kinase C-alpha; Pyrrolidinones; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Calphostin C induces AP1 synthesis and AP1-dependent c-jun transactivation in normal human chondrocytes independent of protein kinase C-alpha inhibition: possible role for c-jun N-terminal kinase.
Topics: Base Sequence; Biological Transport, Active; Cells, Cultured; Chondrocytes; DNA Primers; Genes, fos; Genes, jun; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Naphthalenes; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 1999 |
Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow.
Topics: Adult; Antigens, CD; Antigens, CD34; Bone Marrow Cells; Cell Differentiation; Cell Nucleus; Cells, Cultured; Enzyme Inhibitors; Erythropoietin; Gene Expression Regulation, Enzymologic; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Isoenzymes; Naphthalenes; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Recombinant Proteins; Staurosporine; Stem Cell Factor; Tetradecanoylphorbol Acetate | 2000 |
Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelins; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Glioma; GTP-Binding Proteins; Immediate-Early Proteins; Lysophospholipids; Mitogen-Activated Protein Kinases; Naphthalenes; Pertussis Toxin; Platelet-Derived Growth Factor; Protein Kinase C; Rats; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1999 |
[8-(Diethylamino)octyl-3,4,5-trimethoxybenzoate, HCl], the inhibitor of intracellular calcium mobilization, blocked mitogen-induced T cell proliferation by interfering with the sustained phase of protein kinase C activation.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Division; Concanavalin A; Cyclohexanones; Diglycerides; Enzyme Activation; Gallic Acid; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ionomycin; Mice; Mice, Inbred BALB C; Naphthalenes; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
Ca(2+)-evoked serotonin secretion by parafollicular cells: roles in signal transduction of phosphatidylinositol 3'-kinase, and the gamma and zeta isoforms of protein kinase C.
Topics: Androstadienes; Animals; Calcium; Calcium Channels; Carbazoles; Cell Membrane; Cells, Cultured; Cytosol; Enzyme Inhibitors; Indoles; Isoenzymes; Naphthalenes; Phosphatidylinositol 3-Kinases; Protein Kinase C; Serotonin; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Wortmannin | 2000 |
Ion channel modulation as the basis for neuroprotective action of MS-153.
Topics: Animals; Calcium Channels; Carcinogens; Enzyme Inhibitors; Glutamic Acid; Naphthalenes; Neuroprotective Agents; Nicotinic Acids; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Nicotinic; Riluzole; Sodium Channels; Tetradecanoylphorbol Acetate | 1999 |
Effects of selective protein kinase C inhibitors on the proteolytic down-regulation of L-selectin from chemoattractant-activated neutrophils.
Topics: Acetophenones; Antigens, CD; Benzopyrans; Cells, Cultured; Chemotactic Factors; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Down-Regulation; Humans; Hydroxamic Acids; L-Selectin; Metalloendopeptidases; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophil Activation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate | 2000 |
Novel action of pituitary adenylate cyclase-activating polypeptide. Stimulation of extracellular acidification in rat pituitary GH4C1 cells.
Topics: Animals; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Mitogen-Activated Protein Kinases; Naphthalenes; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 2000 |
Protein kinase C mediates insulin-inhibited Ca2+ transport and contraction of vascular smooth muscle.
Topics: Animals; Biological Transport; Calcium; Carcinogens; Cyclic GMP; Dogs; Enzyme Inhibitors; Female; Femoral Artery; Fluorescent Dyes; Free Radical Scavengers; Fura-2; Hypoglycemic Agents; Insulin; Male; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Vasoconstriction | 2000 |
Differential effects of protein kinase C on the levels of epithelial Na+ channel subunit proteins.
Topics: Aldosterone; Animals; Biological Transport; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Epithelial Sodium Channels; Indoles; Kinetics; Maleimides; Naphthalenes; Protein Kinase C; Protein Structure, Tertiary; RNA, Messenger; Sodium; Sodium Channels; Tetradecanoylphorbol Acetate; Time Factors; Xenopus | 2000 |
Protein kinase C potentiates capacitative Ca2+ entry that links to steroidogenesis in bovine adrenocortical cells.
Topics: Adenosine Triphosphate; Adrenal Cortex; Adrenal Cortex Hormones; Animals; Calcium; Cattle; Cells, Cultured; Manganese; Naphthalenes; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts: involvement of p38 mitogen-activated protein kinase.
Topics: Animals; Endothelial Growth Factors; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Imidazoles; Lymphokines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C; Pyridines; Pyrrolidinones; Receptor, Endothelin A; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
H(2)O(2) opens BK(Ca) channels via the PLA(2)-arachidonic acid signaling cascade in coronary artery smooth muscle.
Topics: Animals; Arachidonic Acid; Coronary Vessels; Enzyme Inhibitors; Hydrogen Peroxide; In Vitro Techniques; Indoles; Ion Channel Gating; Isometric Contraction; Large-Conductance Calcium-Activated Potassium Channels; Lipoxygenase Inhibitors; Muscle, Smooth, Vascular; Naphthalenes; Patch-Clamp Techniques; Phospholipases A; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinase C; Signal Transduction; Swine; Tetradecanoylphorbol Acetate | 2000 |
Phorbol 12-myristate 13-acetate induces alteration in mucin gene expression and biological properties of colon cancer cells.
Topics: Adenocarcinoma; Antigens, Neoplasm; Carcinogens; Cell Adhesion; Cell Movement; Collagen; Colonic Neoplasms; Drug Combinations; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Laminin; Metalloendopeptidases; Mucin 5AC; Mucin-2; Mucin-3; Mucins; Naphthalenes; Neoplasm Invasiveness; Neoplasm Proteins; Protein Kinase C; Proteoglycans; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Endotoxin causes phosphorylation of MARCKS in pulmonary vascular endothelial cells.
Topics: Animals; Cattle; Cell Membrane; Cells, Cultured; Cytosol; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Gram-Negative Bacterial Infections; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Myosin Light Chains; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pyridines; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Thrombin | 2000 |
Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G(i-1) and G(i-2).
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Hormones; Isoenzymes; Muscle, Smooth; Naphthalenes; Phospholipase C beta; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Rabbits; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2000 |
Properties of the inward-rectifying Cl- channel in rat choroid plexus: regulation by intracellular messengers and inhibition by divalent cations.
Topics: Adenosine Triphosphate; Animals; Cadmium; Cations, Divalent; Chloride Channels; Choroid Plexus; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Electric Conductivity; Electrodes; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Naphthalenes; Patch-Clamp Techniques; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Solutions; Tetradecanoylphorbol Acetate; Zinc | 2000 |
Transcriptional regulation of the human interleukin 1beta gene by fibronectin: role of protein kinase C and activator protein 1 (AP-1).
Topics: Blotting, Northern; Blotting, Western; Cell Adhesion; Chloramphenicol O-Acetyltransferase; Dose-Response Relationship, Drug; Electroporation; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Gene Deletion; Gene Expression Regulation; Genes, Reporter; Humans; Interleukin-1; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; NF-kappa B; Oligopeptides; Precipitin Tests; Promoter Regions, Genetic; Protein Kinase C; Receptors, Fibronectin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; U937 Cells | 2000 |
Filopodial behavior is dependent on the phosphorylation state of neuronal growth cones.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Carrier Proteins; Cells, Cultured; Cerebrosides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Genistein; Growth Cones; Indole Alkaloids; Intracellular Signaling Peptides and Proteins; Models, Biological; Myosin-Light-Chain Kinase; Naphthalenes; Neurons; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pseudopodia; Signal Transduction; Snails; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 2000 |
Modulation of alveolar macrophage phagocytosis by leukotrienes is Fc receptor-mediated and protein kinase C-dependent.
Topics: Acetophenones; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Hydroxyurea; Immune Sera; Immunoglobulin G; Klebsiella pneumoniae; Leukotriene Antagonists; Leukotrienes; Macrophages, Alveolar; Microspheres; Naphthalenes; Phagocytosis; Protein Kinase C; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Fc; Receptors, Leukotriene B4; Sheep; Staurosporine; Tetradecanoylphorbol Acetate; Tetrazoles | 2000 |
Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase.
Topics: Adenosine; Biological Transport; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Fetus; Flavonoids; Glucose; Humans; Mitogen-Activated Protein Kinases; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Penicillamine; Protein Kinase C; S-Nitroso-N-Acetylpenicillamine; Tetradecanoylphorbol Acetate; Thioinosine | 2000 |
Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins.
Topics: Animals; Antigens; Cell Degranulation; Clone Cells; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Indoles; Interleukin-2; Lymphocyte Activation; Maleimides; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muromonab-CD3; Naphthalenes; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 2000 |
Epidermal growth factor activates store-operated calcium channels in human glomerular mesangial cells.
Topics: Calcium Channels; Calcium Signaling; Cells, Cultured; Epidermal Growth Factor; Glomerular Mesangium; Humans; Naphthalenes; Patch-Clamp Techniques; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tyrphostins | 2001 |
Expression of macrophage asialoglycoprotein-binding protein is induced through MAPK classical pathway.
Topics: Animals; Blotting, Western; Carrier Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Lectins; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Rats; Receptors, Cell Surface; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; U937 Cells | 2001 |
Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurones.
Topics: beta Catenin; Calcium; Cell Differentiation; Cell Division; Cell Line, Transformed; Cytoskeletal Proteins; Enzyme Inhibitors; gamma-Aminobutyric Acid; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Hypothalamus; Luminescent Proteins; Muscimol; Naphthalenes; Neurites; Neurons; Protein Kinase C; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Trans-Activators; Transfection | 2001 |
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcitriol; Calcium; Calmodulin; Chick Embryo; Egtazic Acid; Enzyme Activation; Fluphenazine; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Naphthalenes; Neomycin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Verapamil | 2001 |
Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes.
Topics: Active Transport, Cell Nucleus; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Calcium; Calcium Signaling; Cell Line; Cell Nucleus; Enzyme Inhibitors; Humans; Ionophores; Leukotrienes; Membrane Lipids; Monocytes; Naphthalenes; Neutrophils; Phospholipases A; Phospholipids; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2001 |
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoembryonic Antigen; Carcinogenicity Tests; Carcinoma; Cell Adhesion Molecules; Colonic Neoplasms; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Naphthalenes; Point Mutation; Protein Kinase C; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 2001 |
Phosphorylation of mitogen-activated protein kinase is regulated by protein kinase C, cyclic 3',5'-adenosine monophosphate, and protein phosphatase modulators during meiosis resumption in rat oocytes.
Topics: Animals; Blotting, Western; Cyclic AMP; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Kinetics; Meiosis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2001 |
A dual role of protein kinase C in insulin signal transduction via adenylyl cyclase signaling system in muscle tissues of vertebrates and invertebrates.
Topics: Adenylyl Cyclases; Androstadienes; Animals; Bacterial Toxins; Diglycerides; Enzyme Inhibitors; Guanylyl Imidodiphosphate; Hormones; Humans; Insulin; Insulin Antagonists; Mollusca; Naphthalenes; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions.
Topics: Albumins; Antigens, CD; Cadherins; Calcium; Calcium Signaling; Carcinogens; Cell Membrane Permeability; Cells, Cultured; Cytoskeletal Proteins; Desmoplakins; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; Hemostatics; Humans; Intercellular Junctions; Iodine Radioisotopes; Isoenzymes; Myosin Light Chains; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Stress Fibers; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 2001 |
Differential inhibition by alpha- and beta-tocopherol of human erythroleukemia cell adhesion: role of integrins.
Topics: Antibodies, Monoclonal; Cell Adhesion; Down-Regulation; Flavonoids; Flow Cytometry; Humans; Integrins; Isoenzymes; K562 Cells; Leukemia, Erythroblastic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; U937 Cells; Vitamin E | 2001 |
Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Colforsin; Culture Techniques; Enzyme Inhibitors; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Myristic Acid; Naphthalenes; Palmitates; Palmitoyl Coenzyme A; Potassium Channels; Protein Kinase C; Tetradecanoylphorbol Acetate | 2001 |
K562 erythroleukemic cells are equipped with multiple mechanisms of resistance to lysis by complement.
Topics: alpha-Amylases; Antigens, CD; CD55 Antigens; CD59 Antigens; Cell Membrane; Complement Activation; Complement System Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Flow Cytometry; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Membrane Cofactor Protein; Membrane Glycoproteins; Naphthalenes; Neutrophils; Plant Proteins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trypsin Inhibitors; Tumor Necrosis Factor-alpha | 2001 |
Nuclear factor-kappa B augments beta(2)-adrenergic receptor expression in human airway epithelial cells.
Topics: Cell Line; Enzyme Inhibitors; Epithelial Cells; Genes, Reporter; Humans; Indoles; Interleukin-1; Leupeptins; Naphthalenes; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Receptors, Adrenergic, beta-2; Respiratory Mucosa; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Up-Regulation | 2001 |
P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
Topics: Actin Cytoskeleton; Androstadienes; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carcinogens; Chromones; Colchicine; Cyclosporine; Cytochalasin B; Diuretics, Osmotic; Enzyme Inhibitors; Hypertonic Solutions; Kidney Tubules, Proximal; Male; Mannitol; Mice; Mice, Knockout; Microtubules; Morpholines; Naphthalenes; Phorbols; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Wortmannin | 2002 |
Effect of protein kinase C on endoplasmic reticulum cholesterol.
Topics: Acetophenones; Benzopyrans; Bryostatins; Calcium; Cell Membrane; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Enzyme Inhibitors; Fibroblasts; Humans; Lactones; Macrolides; Mitogens; Naphthalenes; Protein Isoforms; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2002 |
Expression of toll-like receptors 2 and 4 and CD14 during differentiation of HL-60 cells induced by phorbol 12-myristate 13-acetate and 1 alpha, 25-dihydroxy-vitamin D(3).
Topics: Calcitriol; Cell Differentiation; Dose-Response Relationship, Drug; Drosophila Proteins; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Lipopolysaccharide Receptors; Macrophages; Membrane Glycoproteins; Naphthalenes; Phagocytosis; Protein Kinase C; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2; Toll-Like Receptor 4; Toll-Like Receptors; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2002 |
Time-dependent potentiation of the beta-cell is a Ca2+-independent phenomenon.
Topics: Acylation; Analysis of Variance; Animals; Calcium; Cells, Cultured; Cerulenin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maleimides; Naphthalenes; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Statistics, Nonparametric; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Tunicamycin | 2002 |
[A study of different intracellular signal transduction pathways on phagocytosis of fibronectin by retinal pigment epithelial cells].
Topics: Androstadienes; Cells, Cultured; Enzyme Inhibitors; Fetus; Fibronectins; Genistein; Humans; Naphthalenes; Phagocytosis; Phosphoinositide-3 Kinase Inhibitors; Pigment Epithelium of Eye; Protein Kinase C; Protein-Tyrosine Kinases; Retina; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Regulation of galectin-9 expression and release in Jurkat T cell line cells.
Topics: Animals; Antibody Formation; Antineoplastic Agents; Blotting, Western; Carcinogens; Chemotactic Factors, Eosinophil; DNA Primers; Enzyme Inhibitors; Flow Cytometry; Galectins; Gene Expression Regulation; Humans; Jurkat Cells; Lectins; Metalloendopeptidases; Naphthalenes; Phenylalanine; Protein Kinase C; Rabbits; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Up-Regulation | 2002 |
Pre- and postsynaptic maturation of the neuromuscular junction during neonatal synapse elimination depends on protein kinase C.
Topics: Aging; Animals; Animals, Newborn; Anterior Horn Cells; Axons; Cell Differentiation; Fluorescent Antibody Technique; Male; Muscle, Skeletal; Naphthalenes; Neuromuscular Junction; Neuronal Plasticity; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Synaptic Membranes; Tetradecanoylphorbol Acetate | 2002 |
Study of the functional organization of a novel adenylate cyclase signaling mechanism of insulin action.
Topics: Adenylyl Cyclases; Androstadienes; Animals; Bacterial Toxins; Enzyme Inhibitors; Hormones; Humans; Insulin; Insulin Antagonists; Insulin-Like Growth Factor I; Mollusca; Muscle, Skeletal; Muscle, Smooth; Naphthalenes; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2002 |
Impaired protein kinase C activation/translocation in Epstein-Barr virus-infected monocytes.
Topics: Cell Membrane; Cytosol; DNA-Binding Proteins; Enzyme Inhibitors; Herpesvirus 4, Human; Humans; Indoles; Monocytes; Naphthalenes; Phagocytosis; Protein Kinase C; Protein Transport; Tetradecanoylphorbol Acetate; Trans-Activators; Viral Proteins | 2002 |
[Study on the mechanism of basic fibroblast growth factor (bFGF) release induced by phorbol ester PMA].
Topics: Enzyme Inhibitors; Fibroblast Growth Factor 2; Humans; Naphthalenes; Nasopharyngeal Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Migration of primary cultured rabbit gastric epithelial cells requires intact protein kinase C and Ca2+/calmodulin activity.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Cell Movement; Cells, Cultured; Down-Regulation; Epithelial Cells; Gallic Acid; Gastric Mucosa; Imidazoles; Male; Naphthalenes; Prostaglandins; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 2002 |
Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Carbazoles; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estrenes; In Vitro Techniques; Indoles; Membrane Potentials; Muscle, Smooth, Vascular; Naphthalenes; Norepinephrine; Phenanthridines; Portal Vein; Prazosin; Propranolol; Pyrroles; Pyrrolidinones; Rabbits; Tetradecanoylphorbol Acetate | 2002 |
Immunocytochemical studies on lipid droplet-surface proteins in adrenal cells.
Topics: Adrenal Glands; Animals; Antibody Specificity; Carrier Proteins; Cells, Cultured; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Vesicles; Enzyme Activation; Female; Immunohistochemistry; Lipids; Membrane Proteins; Mitogen-Activated Protein Kinases; Molecular Weight; Naphthalenes; Perilipin-1; Perilipin-2; Phosphoproteins; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2002 |
Protein kinase C activation induces phosphatidylserine exposure on red blood cells.
Topics: Alkaloids; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Humans; Naphthalenes; Phenanthridines; Phosphatidylserines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Protein kinase C-epsilon protects PC12 cells against methamphetamine-induced death: possible involvement of suppression of glutamate receptor.
Topics: Adrenergic Agents; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspase Inhibitors; Cell Survival; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; In Situ Nick-End Labeling; Isoenzymes; Methamphetamine; Naphthalenes; Oligonucleotides, Antisense; PC12 Cells; Protein Kinase C; Protein Kinase C-epsilon; Rats; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.
Topics: Calcimycin; CD28 Antigens; Enzyme Inhibitors; Humans; Immunoblotting; Jurkat Cells; Lymphocyte Activation; Naphthalenes; Phosphoproteins; Phosphorylation; Precipitin Tests; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2003 |
Syndecan-4 distribution during the differentiation of satellite cells isolated from soleus muscle treated by phorbol ester and calphostin C.
Topics: Animals; Blotting, Western; Cell Differentiation; Fluorescent Antibody Technique; Male; Membrane Glycoproteins; Muscle, Skeletal; Naphthalenes; Protein Kinase C; Proteoglycans; Rats; Rats, Wistar; Satellite Cells, Skeletal Muscle; Syndecan-4; Tetradecanoylphorbol Acetate | 2003 |
Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.
Topics: Animals; Anthracenes; Blotting, Northern; Blotting, Western; Carbazoles; Endothelin-1; Enzyme Activators; Enzyme Inhibitors; Gene Expression Regulation; Heat-Shock Proteins; Immunoenzyme Techniques; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Osteoblasts; p38 Mitogen-Activated Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate | 2003 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction.
Topics: Amino Acid Sequence; Animals; Cytosol; Enzyme Inhibitors; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Green Fluorescent Proteins; Hydrolysis; Luminescent Proteins; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis; Naphthalenes; Oocytes; Osmosis; Phosphatidylinositol 4,5-Diphosphate; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Rabbits; RNA, Complementary; Spectrometry, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Xenopus; Xenopus laevis | 2004 |
Endothelin-1 promotes Ca2+ antagonist-insensitive coronary smooth muscle contraction via activation of epsilon-protein kinase C.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Diltiazem; Disease Models, Animal; Drug Resistance; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Naphthalenes; Peptide Fragments; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Verapamil | 2004 |
Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3-L1 Cells; Adipocytes; Animals; Benzylamines; Biphenyl Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Glycerol; Hydroxycholesterols; Indoles; Lignans; Lipolysis; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naphthalenes; Oleic Acid; Phosphorylation; Protein Kinase C; Pyrroles; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles | 2004 |
Protein kinase C activation by Helicobacter pylori in human gastric epithelial cells limits interleukin-8 production through suppression of extracellular signal-regulated kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molecules; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gastric Mucosa; Helicobacter pylori; Humans; I-kappa B Kinase; Indoles; Interleukin-8; Maleimides; Methods; Naphthalenes; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2004 |
Ceramide inhibits L-type calcium channel currents in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Ceramides; Electrophysiology; Enzyme Inhibitors; Naphthalenes; Phenols; Protein Kinase C; Rats; Second Messenger Systems; Sphingomyelin Phosphodiesterase; Tetradecanoylphorbol Acetate | 2004 |
Nucleotide-mediated mucin secretion from differentiated human bronchial epithelial cells.
Topics: Adenosine Triphosphate; Binding, Competitive; Bronchi; Calcium; Carcinogens; Cell Culture Techniques; Cell Differentiation; Chelating Agents; Epithelial Cells; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Lectins; Mucins; Naphthalenes; Pertussis Toxin; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 2004 |
TGF-beta induced hyaluronan synthesis in orbital fibroblasts involves protein kinase C betaII activation in vitro.
Topics: Base Sequence; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Glucuronosyltransferase; Humans; Hyaluronan Synthases; Hyaluronic Acid; Immunohistochemistry; Naphthalenes; Orbit; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2005 |
Vascular endothelial growth factor expression and secretion by retinal pigment epithelial cells in high glucose and hypoxia is protein kinase C-dependent.
Topics: Animals; Blotting, Western; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Glucose; Isoenzymes; Male; Microscopy, Confocal; Naphthalenes; Pigment Epithelium of Eye; Protein Kinase C; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2005 |
The effect of the PKC inhibitor calphostin C and the PKC agonist phorbol 12-myristate 13-acetate on regulation of cytosolic Ca(2+) in mammalian skeletal muscle cells.
Topics: Animals; Calcium; Calcium Signaling; Cell Line; Cytosol; Enzyme Inhibitors; Muscle Fibers, Skeletal; Muscle, Skeletal; Naphthalenes; Protein Kinase C; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Tetradecanoylphorbol Acetate | 2006 |
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells.
Topics: Animals; Apoptosis; beta Catenin; Bone and Bones; Bone Development; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Isoquinolines; Lithium Chloride; Luciferases; Mice; Naphthalenes; NIH 3T3 Cells; Osteoblasts; Parathyroid Hormone; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad3 Protein; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Transforming Growth Factor beta | 2006 |
High glucose enhances inducible nitric oxide synthase expression. Role of protein kinase C-betaII.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Interleukin-1; Male; Mesylates; Muscle, Smooth, Vascular; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type II; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 2006 |
2-Hydroxyestradiol-17beta-induced oocyte maturation in catfish (Heteropneustes fossilis) involves protein kinase C and its interaction with protein phosphatases.
Topics: Animals; Catfishes; Cell Differentiation; Enzyme Inhibitors; Estradiol; Female; Naphthalenes; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate | 2006 |
Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway.
Topics: Alkaloids; Benzophenanthridines; Bosentan; Caveolin 1; Cell Membrane; Cells, Cultured; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Homeostasis; Isoenzymes; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenanthridines; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Transport; Saphenous Vein; Sulfonamides; Tetradecanoylphorbol Acetate | 2006 |
Hyposmotic challenge inhibits inward rectifying K+ channels in cerebral arterial smooth muscle cells.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cerebral Arteries; Female; Hypotonic Solutions; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Tetradecanoylphorbol Acetate; Uridine Triphosphate; Vasoconstrictor Agents | 2007 |
Leishmania amazonensis: PKC-like protein kinase modulates the (Na++K+)ATPase activity.
Topics: Animals; Blotting, Western; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Leishmania mexicana; Leishmaniasis, Diffuse Cutaneous; Naphthalenes; Protein Kinase C; Rabbits; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 2007 |
Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11.
Topics: Animals; Carcinogens; Cells, Cultured; Dimerization; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1-beta; Humans; Inflammation; MafG Transcription Factor; Male; Mutation; Naphthalenes; Nitric Oxide Synthase Type II; Protein Kinase C; Rats; Rats, Sprague-Dawley; Repressor Proteins; Response Elements; RNA, Small Interfering; Signal Transduction; Smad6 Protein; Smad7 Protein; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2007 |
Hyperglycemia impairs isoflurane-induced adenosine triphosphate-sensitive potassium channel activation in vascular smooth muscle cells.
Topics: Anesthetics, Inhalation; Animals; Cells, Cultured; Enzyme Activators; Free Radical Scavengers; Glucose; Hyperglycemia; Isoflurane; KATP Channels; Male; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Polyethylene Glycols; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Vasodilation | 2008 |
Invasion of metastatic human follicular thyroid cancer is inhibited via antagonism of protein kinase C.
Topics: Benzophenanthridines; Cell Line, Tumor; Enzyme Inhibitors; Humans; Naphthalenes; Neoplasm Invasiveness; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin | 1997 |
Interaction between protein kinase C and protein kinase A can modulate transmitter release at the rat neuromuscular synapse.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Analysis of Variance; Animals; Cyclic AMP-Dependent Protein Kinases; Isoquinolines; Membrane Potentials; Naphthalenes; Neuromuscular Junction; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides | 2009 |
The PDE1A-PKCalpha signaling pathway is involved in the upregulation of alpha-smooth muscle actin by TGF-beta1 in adventitial fibroblasts.
Topics: Actins; Animals; Blotting, Western; Cell Transdifferentiation; Cells, Cultured; Connective Tissue; Cyclic Nucleotide Phosphodiesterases, Type 1; Enzyme Activators; Fibroblasts; Fluorescent Antibody Technique; Male; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C-alpha; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1; Up-Regulation | 2010 |
Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.
Topics: Amino Acid Substitution; Animals; Arabidopsis Proteins; Electrophysiological Phenomena; Naphthalenes; Oocytes; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Interaction Domains and Motifs; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection; Xenopus laevis | 2010 |
Regulation of cerebrovascular endothelial peroxisome proliferator activator receptor alpha expression and nitric oxide production by clofibrate.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Clofibrate; Endothelium, Vascular; Enzyme Inhibitors; Hypolipidemic Agents; Microvessels; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; PPAR alpha; Protein Kinase C; Sus scrofa; Tetradecanoylphorbol Acetate | 2010 |
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
Topics: Adenine; Adenosine Triphosphate; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotide Exchange Factors; Humans; Iloprost; In Vitro Techniques; Isoproterenol; Models, Biological; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides | 2011 |
Procoagulant properties of microparticles released from red blood cells in paroxysmal nocturnal haemoglobinuria.
Topics: Blood Coagulation; Calcium; Calpain; Caspases; Cell-Derived Microparticles; Cells, Cultured; Complement Activation; Enzyme Inhibitors; Erythrocytes; Hemoglobinuria, Paroxysmal; Humans; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 2011 |
Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes.
Topics: Aged; Anesthetics, Inhalation; Blotting, Western; Decanoic Acids; Desflurane; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Inhibitors; Female; Glycated Hemoglobin; Glycogen Synthase Kinase 3; Heart; Heart Atria; Humans; Hydroxy Acids; Hypoxia; Ischemic Postconditioning; Isoflurane; KATP Channels; Male; Middle Aged; Mitochondria, Heart; Myocardial Reperfusion Injury; Naphthalenes; Protein Kinase C; Proto-Oncogene Proteins c-akt; Stroke Volume; Tetradecanoylphorbol Acetate | 2011 |
PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; HEK293 Cells; HeLa Cells; Humans; Naphthalenes; Phosphorylation; Protein Isoforms; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Up-Regulation | 2012 |
PKC and PKA regulate AChR dynamics at the neuromuscular junction of living mice.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Female; Isoquinolines; Mice; Muscle Denervation; Naphthalenes; Neuromuscular Junction; Post-Synaptic Density; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Receptors, Cholinergic; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Time-Lapse Imaging | 2013 |
Novel Insights in the Regulation of Phosphatidylserine Exposure in Human Red Blood Cells.
Topics: Annexin A5; Benzophenanthridines; Calcimycin; Calcium; Cells, Cultured; Charybdotoxin; Erythrocyte Count; Erythrocytes; Gene Expression Regulation; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Lysophospholipids; Methomyl; Naphthalenes; Phosphatidylserines; Phospholipid Transfer Proteins; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
Protein Kinase C Regulates ASIC1a Protein Expression and Channel Function via NF-kB Signaling Pathway.
Topics: Acid Sensing Ion Channels; Animals; Carbazoles; Cell Line; Cerebral Cortex; Mice; Naphthalenes; Neurons; Neurotoxicity Syndromes; NF-kappa B; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Kinase C; Proteolysis; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Ubiquitin | 2020 |