tetradecanoylphorbol acetate has been researched along with transforming growth factor alpha in 96 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 72 (75.00) | 18.2507 |
2000's | 20 (20.83) | 29.6817 |
2010's | 4 (4.17) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Caamano, J; Garcia-Palazzo, I; Harris, CC; Iizasa, T; Klein-Szanto, AJ; Metcalf, R; Momiki, S; Welsh, J | 1 |
Besmer, P; Bosenberg, MW; Huang, EJ; Massagué, J; Pandiella, A | 1 |
Fuchs, E; Hutton, ME; Vassar, R | 1 |
Jones, GJ; Thornley, AL | 1 |
Clemente, F; Clerc, P; Estival, A; Tam, JP; Vaysse, N | 1 |
Borowski, P; Buck, F; Fanick, W; Harbers, M; Hilz, H; Hinsch, KD; Lengyel, H | 1 |
Bartlett, JM; Crew, AJ; Langdon, SP; Miller, EP; Miller, WR; Rabiasz, GJ; Scott, WN; Smyth, JF | 1 |
Brickell, PM; Faulkner, L; Katz, DR; Patel, M | 1 |
Bates, B; Goldfarb, M; Hofschneider, PH; Roth, WK; Werner, S | 1 |
Johnson, AL; Tilly, JL | 1 |
Kudlow, JE; Mueller, SG | 1 |
Levine, L; Watanabe, M | 1 |
Bruns, K; Chiang, CP; Delgado, M; Denhardt, DT; Fang, Y; Hamilton, RT; Jang, YJ; Nilsen-Hamilton, M; Parfett, CL; Shim, JK | 1 |
Glinsmann-Gibson, BJ; Korc, M | 1 |
Kudlow, JE; Paterson, AJ; Raja, RH; Shin, TH | 1 |
Bloch, A; Denstman, SC; Guan, XP; Hromchak, RA; Takuma, T | 1 |
Massagué, J; Pandiella, A | 2 |
Ramsdell, JS | 1 |
Beltrán, LM; DiGiovanni, J; Imamoto, A | 1 |
Atlan, H; Markus, M; Panet, R; Snyder, D | 1 |
Atlan, H; Panet, R | 2 |
Goodrum, DD; Sachs, G; Wheeler, LA | 1 |
Brooks, PC; Cheresh, DA; Friedlander, M; Kincaid, CM; Shaffer, RW; Varner, JA | 1 |
Gohda, E; Kataoka, H; Matsunaga, T; Takebe, T; Yamamoto, I | 1 |
Pan, M; Stevens, BR | 1 |
Greene, MI; Samanta, A | 1 |
Braun, L; Goto-Mandeville, R; Mirapuri, M; Sears, WL | 1 |
Levine, AE; Ramesh, G | 1 |
Bishop, PR; Coffey, RJ; DuBois, RN; Graves-Deal, R | 1 |
Malm, C; Walz, TM; Wasteson, A | 1 |
Beltrán, LM; DiGiovanni, J; Kiguchi, K; Rho, O; You, J | 1 |
Arribas, J; Massagué, J | 1 |
Bonney, RC; Franks, S; Watson, H | 1 |
Lewintre, EJ; Orava, M; Vihko, R | 1 |
Levine, AE | 1 |
Adams, LA; Pfeifer, RW | 1 |
Harano, T; Mizuno, K | 1 |
Awad, J; Bishop, PR; DuBois, RN; Morrow, J; Roberts, LJ | 1 |
Johnson, AL; Levorse, JM | 1 |
Eckhardt, JN; Greenhalgh, DA; Roop, DR; Rothnagel, JA; Wang, XJ | 1 |
Brown, SB; Ellem, KA; Kluck, RM | 1 |
Bosenberg, MW; Massagué, J; Pandiella, A | 1 |
Fürstenberger, G; Kast, R; Marks, F | 1 |
Birkedal-Hansen, B; Birkedal-Hansen, H; Lyons, JG; Pierson, MC; Whitelock, JM | 1 |
Ignar-Trowbridge, DM; Korach, KS; McLachlan, JA; Parker, MG; Pimentel, M | 1 |
Baselga, J; Kim, YM; Mendelsohn, J; Pandiella, A | 1 |
Arribas, J; Coodly, L; Kishimoto, TK; Massagué, J; Rose-John, S; Vollmer, P | 1 |
Donehower, LA; Greenhalgh, DA; Roop, DR; Wang, XJ | 2 |
Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Pernod, G | 1 |
Cheresh, DA; Mackman, N; Mueller, BM; Parry, GC; Rosenberg, S; Strömblad, S; Yebra, M | 1 |
Hosono, T; Ito, A; Mori, Y; Nagase, H; Sato, T | 1 |
Lunec, J; Nutt, JE | 1 |
Blackburn, WD; Minghetti, PP; Zhang, HG | 1 |
Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Morera, AM; Pernod, G | 1 |
Beltrán, L; DiGiovanni, J; Dubowski, A; Kiguchi, K | 1 |
Burghardt, R; Porter, W; Safe, SH; Wang, WL | 1 |
Bernfield, M; Fitzgerald, ML; Subramanian, SV | 1 |
Arribas, J; López-Casillas, F; Massagué, J | 1 |
Bol, DK; Budunova, IV; Coghlan, LG; Conti, CJ; DiGiovanni, J; Fischer, SM; Gimenez-Conti, I; Kiguchi, K; Rundhaug, JE; Slaga, TJ; Stern, MC; Winberg, LD | 1 |
Clapp, C; Domenzáin, C; Martínez de la Escalera, G; Ochoa, A | 1 |
Awad, J; Bishop, P; DuBois, R; Morrow, J; Roberts, L; Tsujii, M | 1 |
Formanek, M; Knerer, B; Kornfehl, J; Millesi, W; Temmel, A; Thurnher, D | 1 |
Boorman, GA; Bruccoleri, A; Chen, GS; Foley, JF; Germolec, DR; Humble, MC; Luster, MI; Simeonova, PP; Spalding, J; Yoshida, T; Yu, HS | 1 |
Auersperg, N; Kievit, P; McClellan, M; Rodland, K | 1 |
Black, T; Elliott, G; Merewether, LA; Meyer, S; Yabkowitz, R; Yamane, HK | 1 |
Hanai, H; Kajimura, M; Kaneko, E; Kodaira, M; Lin, S; Takeuchi, K | 1 |
Gibson, PR; Wilson, AJ | 1 |
Kimura, M; Ogihara, M | 1 |
Bailey, JL; Fortier, MA; Guilbault, LA; Legault, S; Rouillier, P | 1 |
Greenhalgh, DA; Liefer, KM; Roop, DR; Wang, XJ | 1 |
Derynck, R; Fan, H; Shi, W; Shum, L | 1 |
Aoki, H; Arakawa, Y; Hayashi, J; Hino, O; Kajino, K; Moriyama, M | 1 |
Nakazawa, S; Narita, T; Ohta, S; Sugita, K; Taga, T | 1 |
Denys, A; Hichami, A; Khan, NA; Maume, B | 1 |
Hallbeck, AL; Walz, TM; Wasteson, A | 1 |
Díaz-Rodríguez, E; Esparís-Ogando, A; Montero, JC; Pandiella, A; Yuste, L | 1 |
Dandachi, N; Doppelmayr, H; Fellner, T; Hauser-Kronberger, C; Moré, E; Obrist, P; Paulweber, B; Sandhofer, F | 1 |
Derynck, R; Fan, H; Turck, CW | 1 |
Arnott, CH; Balkwill, FR; East, N; Moore, RJ; Scallon, BJ; Scott, KA; Shealy, DJ; Thompson, RG | 1 |
Chang, WC | 1 |
Chao, W; Choi, SY; Kim, SY; Volsky, DJ | 1 |
Blobel, CP; Hartmann, D; Higashiyama, S; Kelly, K; Peschon, J; Saftig, P; Sahin, U; Weskamp, G; Zhou, HM | 1 |
Deng, C; Li, AG; Lu, SL; Wang, XJ; Zhang, MX | 1 |
Edbrooke, MR; Hewson, CA; Johnston, SL | 1 |
Nadel, JA; Shao, MX | 1 |
Bolotin, D; Chu, DH; Fuchs, E; Polak, L; Wang, X; Williams, T | 1 |
Adachi, S; Iwamoto, R; Mekada, E; Mizushima, H; Ohishi, M; Wang, X | 1 |
Blobel, CP; Hartmann, D; Horiuchi, K; Le Gall, S; Murphy, G; Reiss, K; Saftig, P; Schulte, M; Toyama, Y; Yamaguchi, T | 1 |
Cora, EM; Maihle, NJ; Negron-Vega, L; Nieves-Alicea, R; Perez-Torres, M; Valle, BL | 1 |
BenMohamed, F; Charpigny, G; Chignard, M; Garcia-Verdugo, I; Leduc, D; Ollero, M; Tattermusch, S; Touqui, L | 1 |
Armbruster, N; Bell, GW; Cermeno, E; Dang, M; Hartmann, M; Herrlich, A; Lauffenburger, DA; Lodish, HF; Miller, MA; Root, DE | 1 |
Sano, S; Sato, K; Takaishi, M; Tokuoka, S | 1 |
Babendreyer, A; Cataldo, D; Dreymueller, D; Groth, E; Grötzinger, J; Higashiyama, S; Lorenzen, I; Ludwig, A; Pasqualon, T; Pruessmeyer, J; Schumacher, J | 1 |
1 review(s) available for tetradecanoylphorbol acetate and transforming growth factor alpha
Article | Year |
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Cell signaling and gene regulation of human 12(S)-lipoxygenase expression.
Topics: Arachidonate 12-Lipoxygenase; Base Sequence; Epidermal Growth Factor; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Signal Transduction; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2003 |
95 other study(ies) available for tetradecanoylphorbol acetate and transforming growth factor alpha
Article | Year |
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A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
Topics: Animals; Biomarkers, Tumor; Bronchi; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Epithelium; ErbB Receptors; Gelatinases; Humans; Isoenzymes; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Nitrosamines; Pepsin A; Rats; Smoke; Smoking; Tetradecanoylphorbol Acetate; Trachea; Transforming Growth Factor alpha; Transplantation, Heterologous | 1992 |
Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Endopeptidases; Hematopoietic Cell Growth Factors; Isoflurophate; Kinetics; Molecular Sequence Data; Protease Inhibitors; Protein Precursors; Protein Processing, Post-Translational; Rats; Sequence Homology, Amino Acid; Stem Cell Factor; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 1992 |
Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.
Topics: Animals; Base Sequence; Disease Models, Animal; DNA, Neoplasm; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Wounds and Injuries | 1992 |
In vitro secretion of transforming growth factor alpha (TGF-alpha): a comparison of the A431 cell line with three human oesophageal squamous cell carcinoma lines.
Topics: Carcinoma, Squamous Cell; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Humans; In Vitro Techniques; Secretory Rate; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1992 |
Decreased expression of transforming growth factor alpha during differentiation of human pancreatic cancer cells.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Gene Expression Regulation; Humans; Pancreatic Neoplasms; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Epigenetic activation of Gi-2 protein, the product of a putative protooncogene, mediates tumor promotion in vitro.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Growth Factor; Female; GTP-Binding Proteins; Mice; Molecular Sequence Data; Mutation; Ovarian Neoplasms; Pertussis Toxin; Phenotype; Phospholipases A; Phospholipases A2; Proto-Oncogene Proteins; Rats; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Virulence Factors, Bordetella | 1992 |
Growth control by epidermal growth factor and transforming growth factor-alpha in human lung squamous carcinoma cells.
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Cell Line; Culture Media; Epidermal Growth Factor; ErbB Receptors; Humans; Immunohistochemistry; Lung Neoplasms; Protein Precursors; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1992 |
Regulation of c-fgr messenger RNA levels in U937 cells treated with different modulating agents.
Topics: Animals; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Lymphotoxin-alpha; Macrophages; Monocytes; Proto-Oncogene Proteins; RNA, Messenger; src-Family Kinases; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Fibroblast growth factor 5 proto-oncogene is expressed in normal human fibroblasts and induced by serum growth factors.
Topics: Animals; Blotting, Northern; Bucladesine; Cell Line; Cells, Cultured; Cycloheximide; Epidermal Growth Factor; Fibroblast Growth Factor 5; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Growth Substances; Humans; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Mas; RNA, Messenger; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Transformation, Genetic; Transforming Growth Factor alpha | 1991 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
Transforming growth factor-beta (TGF beta) inhibits TGF alpha expression in bovine anterior pituitary-derived cells.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Kinetics; Pituitary Gland, Anterior; Poly A; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1991 |
Amplification of prostaglandin I2 production by thapsigargin.
Topics: Animals; Binding Sites; Cell Line; Epidermal Growth Factor; Epoprostenol; Fibroblast Growth Factor 2; Heparin; Interleukin-1; Liver; Lyngbya Toxins; Rats; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 1991 |
Regulation of the expression of mitogen-regulated protein (MRP; proliferin) and cathepsin L in cultured cells and in the murine placenta.
Topics: 3T3 Cells; Animals; Cathepsin L; Cathepsins; Cells, Cultured; Cysteine Endopeptidases; Endopeptidases; Epidermal Growth Factor; Fibroblast Growth Factors; Gene Expression Regulation; Gestational Age; Glycoproteins; Growth Substances; Humans; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins; Mice; Placenta; Placentation; Prolactin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1991 |
Regulation of transforming growth factor-alpha mRNA expression in T3M4 human pancreatic carcinoma cells.
Topics: Dactinomycin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Nucleic Acid Hybridization; Pancreatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1991 |
Transcriptional regulation of the human transforming growth factor-alpha gene.
Topics: Base Sequence; Breast Neoplasms; Dexamethasone; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Humans; In Vitro Techniques; Luciferases; Molecular Sequence Data; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Transforming Growth Factor alpha; Tretinoin; Triiodothyronine; Tumor Cells, Cultured | 1991 |
Tumor necrosis factor-alpha, transforming growth factor-beta, and tetradecanoylphorbol acetate: competence factors for ML-1 human myeloblastic leukemia cell differentiation.
Topics: Cell Differentiation; Humans; Leukemia, Myeloid, Acute; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Line; Cell Membrane; Endopeptidases; Models, Biological; Pancreatic Elastase; Protein Conformation; Protein Precursors; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 1991 |
Transforming growth factor-alpha and -beta are potent and effective inhibitors of GH4 pituitary tumor cell proliferation.
Topics: Activins; Animals; Cell Adhesion; Cell Count; Cell Division; DNA; Inhibins; Interphase; Mitosis; Phorbol 12,13-Dibutyrate; Pituitary Neoplasms; Prolactin; Protein Kinase C; Rats; Recombinant Proteins; S Phase; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Cells, Cultured | 1991 |
Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Kinetics; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1991 |
Evidence for autocrine/paracrine growth stimulation by transforming growth factor-alpha during the process of skin tumor promotion.
Topics: Animals; Anthracenes; Binding, Competitive; Carcinogens; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Female; Mice; Protein Kinase C; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1991 |
Phorbol ester TPA inhibits the stimulation of bumetanide-sensitive Na+/K+/Cl- transporter by different mitogens in quiescent BALB/c 3T3 mouse fibroblasts.
Topics: Animals; Bumetanide; Carrier Proteins; Cell Line; Epidermal Growth Factor; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mice; Mice, Inbred BALB C; Mitogens; Platelet-Derived Growth Factor; Rubidium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Thrombin; Transforming Growth Factor alpha | 1991 |
Stimulation of bumetanide-sensitive Na+/K+/Cl- cotransport by different mitogens in synchronized human skin fibroblasts is essential for cell proliferation.
Topics: Bumetanide; Carrier Proteins; Cell Cycle; Cell Division; Cells, Cultured; DNA; Fibroblast Growth Factors; Fibroblasts; Furosemide; G1 Phase; Humans; Insulin-Like Growth Factor I; Mitogens; Platelet-Derived Growth Factor; Protein Kinase C; Resting Phase, Cell Cycle; S Phase; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Thrombin; Transforming Growth Factor alpha | 1991 |
Bumetanide-sensitive Na+/K+/Cl- transporter is stimulated by phorbol ester and different mitogens in quiescent human skin fibroblasts.
Topics: Bumetanide; Carrier Proteins; Cell Division; Chlorides; DNA Replication; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; In Vitro Techniques; Insulin-Like Growth Factor I; Membrane Proteins; Mitogens; Platelet-Derived Growth Factor; Potassium; Protein Kinase C; Rubidium; Skin; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Thrombin; Transforming Growth Factor alpha | 1990 |
Role of protein kinase C in the regulation of cytosolic Ca2+ in A431 cells: separation of growth factor and bradykinin pathways.
Topics: Alkaloids; Bradykinin; Calcium; Cytosol; Down-Regulation; Epidermal Growth Factor; Humans; Ionomycin; Manganese; Protein Kinase C; Pyrimidinones; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1990 |
Definition of two angiogenic pathways by distinct alpha v integrins.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Cornea; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblast Growth Factor 2; Integrins; Lymphokines; Naphthalenes; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptides, Cyclic; Protein Kinase C; Rabbits; Receptors, Vitronectin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Induction of hepatocyte growth factor in human skin fibroblasts by epidermal growth factor, platelet-derived growth factor and fibroblast growth factor.
Topics: Blotting, Northern; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Infant; Kinetics; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Protein kinase C-dependent regulation of L-arginine transport activity in Caco-2 intestinal cells.
Topics: Alkaloids; Arginine; Benzophenanthridines; Biological Transport; Caco-2 Cells; Carrier Proteins; Cell Differentiation; Cycloheximide; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Kinetics; Membrane Glycoproteins; Membrane Proteins; Phenanthridines; Protein Kinase C; Receptors, Virus; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Up-Regulation | 1995 |
A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions.
Topics: Animals; Cell Line; Cell Nucleus; Chromatin; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Ethers, Cyclic; Growth Substances; Ligands; Mice; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Receptor, ErbB-2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 1995 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on human papillomavirus type 16-positive keratinocytes at different stages of transformation.
Topics: Cell Differentiation; Cell Division; Cell Transformation, Viral; Gene Expression Regulation, Viral; Humans; In Vitro Techniques; Keratinocytes; Oncogenes; Papillomaviridae; Proto-Oncogenes; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Virus Replication | 1995 |
Pro-transforming growth factor-alpha processing in human colon carcinoma cells: role of protein kinase C.
Topics: Colonic Neoplasms; Humans; Isoenzymes; Naphthalenes; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1995 |
Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine.
Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Cell Division; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Epithelium; Ethers, Cyclic; Gene Expression Regulation; Immediate-Early Proteins; In Situ Hybridization; Intestinal Mucosa; Male; Molecular Sequence Data; Okadaic Acid; Protein Biosynthesis; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transforming Growth Factor alpha; Tristetraprolin; Zinc Fingers | 1995 |
Expression of the transforming growth factor alpha protooncogene in differentiating human promyelocytic leukemia (HL-60) cells.
Topics: Cell Differentiation; Gene Expression; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Proto-Oncogenes; RNA; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis.
Topics: Administration, Topical; Animals; Anthracenes; Base Sequence; Blotting, Northern; Carcinogens; DNA Primers; Ethers, Cyclic; Female; Fluorescent Antibody Technique; Gene Expression; Mice; Mice, Inbred SENCAR; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; RNA, Messenger; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha | 1995 |
Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.
Topics: Amyloid beta-Protein Precursor; Animals; Base Sequence; Biological Transport; CHO Cells; Cricetinae; Hydrolysis; Membrane Proteins; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Rats; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1995 |
Characterization of epidermal growth factor receptor in human endometrial cells in culture.
Topics: Cells, Cultured; Down-Regulation; Endometrium; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Protein Binding; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Regulation of 17 beta-hydroxysteroid dehydrogenase type 1 by epidermal growth factor and transforming growth factor-alpha in choriocarcinoma cells.
Topics: 17-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Catechols; Choriocarcinoma; Epidermal Growth Factor; Humans; Nitriles; Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrphostins | 1994 |
Involvement of protein kinase C and an elastase-like enzyme in the processing of transforming growth factor-alpha in human colon carcinoma cell lines.
Topics: Colonic Neoplasms; Detergents; Enzyme Activation; Humans; Pancreatic Elastase; Protease Inhibitors; Protein Kinase C; Sensitivity and Specificity; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1994 |
Transforming growth factor-alpha expression in peritoneal macrophages elicited from SENCAR and B6C3F1 mice: responses to lipopolysaccharide and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Base Sequence; DNA Primers; Female; Gene Expression; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Sequence Data; Regression Analysis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Phorbol ester-induced activation of a membrane-bound candidate pro-transforming growth factor-alpha processing enzyme.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; CHO Cells; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cricetinae; Endopeptidases; Enzyme Activation; Molecular Sequence Data; Protein Processing, Post-Translational; Serine Endopeptidases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Regulation of eicosanoid production and mitogenesis in rat intestinal epithelial cells by transforming growth factor-alpha and phorbol ester.
Topics: Animals; Cell Division; Cell Line; DNA; DNA Probes; Eicosanoids; Electron Transport Complex IV; Enzyme Induction; Epithelial Cells; Epithelium; Gene Expression Regulation, Enzymologic; Indomethacin; Intestinal Mucosa; Kinetics; Mice; Microsomes; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Sulindac; Tetradecanoylphorbol Acetate; Thymidine; Transfection; Transforming Growth Factor alpha | 1994 |
Regulation of steroid production in ovarian stromal tissue from 5- to 8-week-old pullets and laying hens.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Estradiol; Female; Gonadal Steroid Hormones; Luteinizing Hormone; Ovary; Progesterone; Sexual Maturation; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression.
Topics: Animals; Base Sequence; DNA Primers; Gene Expression; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Induction of cell surface peptidase activity: a global response to cell stress correlated with apoptosis.
Topics: Amino Acid Sequence; Apoptosis; Cell Cycle; Cell Membrane; Cycloheximide; Dactinomycin; Dichlororibofuranosylbenzimidazole; Endopeptidases; Enzyme Induction; HeLa Cells; Humans; Membrane Proteins; Mitomycin; Molecular Sequence Data; Peptide Fragments; Protein Synthesis Inhibitors; Stress, Physiological; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Ultraviolet Rays | 1994 |
Activated release of membrane-anchored TGF-alpha in the absence of cytosol.
Topics: Aluminum; Aluminum Compounds; Animals; Cell Membrane; Cell Membrane Permeability; CHO Cells; Cricetinae; Fluorides; Fluorine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection; Transforming Growth Factor alpha | 1993 |
Activation of cytosolic phospholipase A2 by transforming growth factor-alpha in HEL-30 keratinocytes.
Topics: Animals; Arachidonic Acids; Biological Transport; Calcium; Cell Line; Cytosol; Enzyme Activation; ErbB Receptors; Humans; Keratinocytes; Mice; Phospholipases A; Phospholipases A2; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tyrosine | 1993 |
Interleukin-1 beta and transforming growth factor-alpha/epidermal growth factor induce expression of M(r) 95,000 type IV collagenase/gelatinase and interstitial fibroblast-type collagenase by rat mucosal keratinocytes.
Topics: Alkaloids; Animals; Cell Line; Collagenases; Dexamethasone; Endopeptidases; Enzyme Induction; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Fibroblasts; Gelatinases; Interleukin-1; Keratinocytes; Mammary Neoplasms, Experimental; Molecular Weight; Mouth Mucosa; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; Binding Sites; Cell Division; CHO Cells; Cricetinae; Epidermal Growth Factor; Estradiol; Humans; Insulin-Like Growth Factor I; Molecular Sequence Data; Protein Kinase C; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Autocrine regulation of membrane transforming growth factor-alpha cleavage.
Topics: Animals; Antibodies; Autoradiography; Calcimycin; Carcinoma, Squamous Cell; Cell Membrane; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.
Topics: Amyloid beta-Protein Precursor; Animals; Antigens, CD; Cell Membrane; CHO Cells; Cricetinae; Genetic Complementation Test; Hydroxamic Acids; Kinetics; L-Selectin; Membrane Proteins; Metalloendopeptidases; Mutagenesis; Phenanthrolines; Phenotype; Protease Inhibitors; Protein Precursors; Receptors, Interleukin; Receptors, Interleukin-6; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 1996 |
Paradoxical tumor inhibitory effect of p53 loss in transgenic mice expressing epidermal-targeted v-rasHa, v-fos, or human transforming growth factor alpha.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epidermis; Genes, fos; Genes, p53; Genes, ras; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Mice, Transgenic; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transgenes | 1996 |
Plasminogen activator inhibitor-1 regulation in cultured rat peritubular cells by basic fibroblast growth factor and transforming growth factor-alpha.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Fibroblast Growth Factor 2; Kidney Tubules; Plasminogen Activator Inhibitor 1; Protein Kinase C; Rats; Recombinant Proteins; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1996 |
Requirement of receptor-bound urokinase-type plasminogen activator for integrin alphavbeta5-directed cell migration.
Topics: Cell Movement; Collagen; Gene Expression Regulation; Humans; Integrins; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Receptors, Vitronectin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator; Vitronectin | 1996 |
Translational augmentation of pro-matrix metalloproteinase 3 (prostromelysin 1) and a tissue inhibitor of metalloproteinases (TIMP)-1 mRNAs by epidermal growth factor and transforming growth factor alpha, but not by interleukin 1 alpha or 12-O-tetradecano
Topics: Cervix Uteri; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Epidermal Growth Factor; Female; Fibroblasts; Glycoproteins; Humans; Interleukin-1; Metalloendopeptidases; Protein Biosynthesis; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor alpha | 1996 |
Induction of metalloproteinase (MMP1) expression by epidermal growth factor (EGF) receptor stimulation and serum deprivation in human breast tumour cells.
Topics: Blotting, Northern; Breast Neoplasms; Collagenases; Culture Media, Serum-Free; Cycloheximide; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Matrix Metalloproteinase 1; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Characterization of a SV40-transformed rheumatoid synovial fibroblast cell line which retains genotypic expression patterns: a model for evaluation of anti-arthritic agents.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line, Transformed; Dexamethasone; Fibroblasts; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Genes, jun; Genotype; Humans; Interleukin-1; Metalloendopeptidases; Models, Biological; Simian virus 40; Synovial Membrane; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Tumor necrosis factor-alpha regulates plasminogen activator inhibitor-1 in rat testicular peritubular cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Staurosporine; Testis; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
Analysis of the ability of 12-O-tetradecanoylphorbol-13-acetate to induce epidermal hyperplasia, transforming growth factor-alpha, and skin tumor promotion in wa-1 mice.
Topics: Amphiregulin; Animals; Antineoplastic Agents; Carcinogens; EGF Family of Proteins; Epidermal Growth Factor; Female; Glycoproteins; Growth Substances; Heparin; Heparin-binding EGF-like Growth Factor; Hyperplasia; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred SENCAR; Mice, Mutant Strains; Neutrophils; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Aryl Hydrocarbon Receptor Nuclear Translocator; Breast Neoplasms; Cell Division; Cell Nucleus; Cytochrome P-450 CYP1A1; Diethylstilbestrol; DNA-Binding Proteins; DNA, Neoplasm; Estradiol; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Growth Inhibitors; Humans; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor alpha; Tretinoin; Tumor Cells, Cultured | 1997 |
Regulated shedding of syndecan-1 and -4 ectodomains by thrombin and growth factor receptor activation.
Topics: Amino Acid Sequence; Amphiregulin; Antibodies; Cell Membrane; Cells, Cultured; EGF Family of Proteins; Endothelial Growth Factors; Endothelium, Vascular; Epidermal Growth Factor; Epitopes; ErbB Receptors; Glycoproteins; Growth Substances; GTP-Binding Proteins; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Membrane Glycoproteins; Peptide Fragments; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proteoglycans; Receptors, Growth Factor; Receptors, Thrombin; Recombinant Proteins; Skin; Syndecan-1; Syndecan-4; Syndecans; Tetradecanoylphorbol Acetate; Thrombin; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wounds and Injuries | 1997 |
Role of the juxtamembrane domains of the transforming growth factor-alpha precursor and the beta-amyloid precursor protein in regulated ectodomain shedding.
Topics: Amyloid beta-Protein Precursor; Animals; Carcinogens; Cell Membrane; CHO Cells; Cricetinae; Enzyme Activation; Flow Cytometry; Kinetics; Protein Kinase C; Protein Precursors; Proteoglycans; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 1997 |
Changes in protein expression during multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinogens; Connexin 26; Connexins; Cyclin D1; Cyclins; Epidermal Growth Factor; Female; gamma-Glutamyltransferase; Heparin-binding EGF-like Growth Factor; Integrin alpha6beta4; Integrins; Intercellular Signaling Peptides and Proteins; Keratins; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Oncogene Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Differential effects of basic fibroblast growth factor, epidermal growth factor, transforming growth factor-alpha, and insulin-like growth factor-I on a hypothalamic gonadotropin-releasing hormone neuronal cell line.
Topics: Animals; Carcinogens; Cell Count; Cell Division; Cell Line, Transformed; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression; Gonadotropin-Releasing Hormone; Gonadotropins; Growth Substances; Hypothalamus; Insulin-Like Growth Factor I; Mice; Neurites; Neurons; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Transforming Growth Factor alpha; Transgenes; Tritium | 1997 |
Eicosanoid production and growth regulation in rat intestinal epithelial cells.
Topics: Animals; Arachidonic Acid; Cell Division; Cell Line; DNA; DNA Replication; Eicosanoids; Intestinal Mucosa; Rats; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Oral keratinocytes derived from the peritonsillar mucosa express the proinflammatory cytokine IL-6 without prior stimulation.
Topics: Cell Separation; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Flow Cytometry; Gene Expression; Humans; Interleukin-1; Interleukin-2; Interleukin-4; Interleukin-6; Interleukin-8; Keratinocytes; Mouth Mucosa; Palatine Tonsil; Platelet-Derived Growth Factor; Polymerase Chain Reaction; Receptors, Interleukin; Receptors, Interleukin-1; Receptors, Interleukin-6; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1998 |
Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors.
Topics: Animals; Antibodies; Arsenic; Cell Division; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Distribution; Transforming Growth Factor alpha | 1998 |
Regulation of proliferation and apoptosis by epidermal growth factor and protein kinase C in human ovarian surface epithelial cells.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Female; Gene Expression Regulation; Genes, Immediate-Early; Humans; Insulin-Like Growth Factor I; Ovary; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
Inflammatory cytokines and vascular endothelial growth factor stimulate the release of soluble tie receptor from human endothelial cells via metalloprotease activation.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cytokines; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblast Growth Factor 2; Humans; Interleukin-1; Kinetics; Lymphokines; Metalloendopeptidases; Molecular Sequence Data; Peptide Fragments; Receptor Protein-Tyrosine Kinases; Receptor, TIE-1; Receptors, TIE; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Functional muscarinic m3 receptor expressed in gastric cancer cells stimulates tyrosine phosphorylation and MAP kinase.
Topics: Atropine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Densitometry; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Naphthalenes; Phosphorylation; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1999 |
Role of epidermal growth factor receptor in basal and stimulated colonic epithelial cell migration in vitro.
Topics: Acetates; Butyrates; Caco-2 Cells; Cell Movement; Colon; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Hepatocyte Growth Factor; Humans; Intestinal Mucosa; Mitogens; Propionates; Protein Kinase C; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Valerates | 1999 |
Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by alpha- and beta-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Brimonidine Tartrate; Cell Division; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Drug Interactions; ErbB Receptors; Isoquinolines; Liver; Male; Metaproterenol; Mitogen-Activated Protein Kinase Kinases; Phenylephrine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinases; Quinoxalines; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases | 1999 |
Intracellular regulation of estradiol and progesterone production by cultured bovine granulosa cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Genistein; Granulosa Cells; Progesterone; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, FSH; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
12-O-tetradecanoylphorbol-13-acetate promotion of transgenic mouse epidermis coexpressing transforming growth factor-alpha and v-fos: acceleration of autonomous papilloma formation and malignant conversion via c-Ha-ras activation.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, ras; Humans; Mice; Mice, Transgenic; Oncogene Proteins v-fos; Papilloma; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
The tetraspanin CD9 associates with transmembrane TGF-alpha and regulates TGF-alpha-induced EGF receptor activation and cell proliferation.
Topics: Animals; Antigens, CD; Cell Division; Cell Membrane; CHO Cells; Cricetinae; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; ErbB Receptors; Gene Expression; Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Tetraspanin 29; Transforming Growth Factor alpha | 2000 |
Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha.
Topics: 3T3 Cells; Animals; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; ets-Domain Protein Elk-1; Hepacivirus; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured; Viral Core Proteins | 2000 |
Cooperation between Ha-ras and fos or transforming growth factor alpha overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis.
Topics: Animals; Carcinogens; Epidermis; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, p53; Genes, ras; Keratins; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Transgenic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2000 |
The autocrine loop of epidermal growth factor receptor-epidermal growth factor / transforming growth factor-alpha in malignant rhabdoid tumor cell lines: heterogeneity of autocrine mechanism in TTC549.
Topics: Adult; Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cell Line; Child; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization; Male; Reverse Transcriptase Polymerase Chain Reaction; Rhabdoid Tumor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2001 |
Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells.
Topics: 3T3 Cells; Animals; Cell Division; Docosahexaenoic Acids; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2001 |
Interleukin-6 enhances transforming growth factor-alpha mRNA expression in macrophage-like human monocytoid (U-937-1) cells.
Topics: Cell Differentiation; Cholecalciferol; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Interleukin-6; Macrophages; Receptors, Interleukin-6; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 2001 |
Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.
Topics: ADAM Proteins; ADAM17 Protein; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Line; Cell Membrane; CHO Cells; Cricetinae; Endopeptidases; Growth Substances; Metalloendopeptidases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuregulin-1; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase C; Protein Precursors; Rats; Solubility; Sorbitol; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Ultraviolet Rays | 2002 |
Activation of the MAP kinase pathway induces chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) expression in human breast cancer cell lines.
Topics: Blotting, Western; Breast Neoplasms; Butadienes; COUP Transcription Factor I; COUP Transcription Factor II; COUP Transcription Factors; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Female; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Oncostatin M; Peptides; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2003 |
Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; CHO Cells; Cricetinae; Cytoplasm; Genetic Vectors; HeLa Cells; Humans; MAP Kinase Signaling System; Metalloendopeptidases; Molecular Sequence Data; Peptides; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha; Trypsin | 2003 |
An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinogens; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunity, Innate; Keratinocytes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Staging; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2003 |
Transcriptional regulation of human excitatory amino acid transporter 1 (EAAT1): cloning of the EAAT1 promoter and characterization of its basal and inducible activity in human astrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Base Sequence; Blotting, Northern; Cells, Cultured; Cloning, Molecular; Cyclic CMP; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Epidermal Growth Factor; Excitatory Amino Acid Transporter 1; Fetus; Gene Expression Regulation; Glutamic Acid; Humans; Luciferases; Mice; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Rats; Regulatory Sequences, Nucleic Acid; RNA; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription Initiation Site; Transcription, Genetic; Transcriptional Activation; Transfection; Transforming Growth Factor alpha; Upstream Stimulatory Factors | 2003 |
Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
Topics: ADAM Proteins; ADAM12 Protein; ADAM17 Protein; Amphiregulin; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betacellulin; Cells, Cultured; Disintegrins; EGF Family of Proteins; Embryo, Mammalian; Endopeptidases; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Fibroblasts; Genotype; Glycoproteins; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Knockout; Muscle Proteins; Phenylalanine; Protease Inhibitors; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Thiophenes; Transforming Growth Factor alpha | 2004 |
Smad3 knockout mice exhibit a resistance to skin chemical carcinogenesis.
Topics: Animals; Apoptosis; Disease Susceptibility; DNA-Binding Proteins; Epidermis; Female; Inflammation; Keratinocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Smad3 Protein; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transforming Growth Factor alpha | 2004 |
PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanisms.
Topics: Base Sequence; Bronchi; Cell Line; DNA Primers; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Humans; MAP Kinase Signaling System; Mucin 5AC; Mucins; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor alpha | 2004 |
Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.
Topics: ADAM Proteins; ADAM17 Protein; Cells, Cultured; Dual Oxidases; Epithelial Cells; Flavoproteins; Gene Expression Regulation; Humans; Leukocyte Elastase; Metalloendopeptidases; Mucin 5AC; Mucins; NADPH Oxidases; Protein Kinase C; Protein Kinase C-delta; Reactive Oxygen Species; Respiratory Mucosa; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2005 |
AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis.
Topics: Animals; Animals, Newborn; Calcium; Caspase 3; Caspases; Cell Proliferation; Chromatin Immunoprecipitation; Chromones; Dermis; DNA; Embryo, Mammalian; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Gene Expression; Gene Expression Regulation; Hair Diseases; Integrases; Keratinocytes; Keratins; Ki-67 Antigen; MAP Kinase Signaling System; Mice; Mice, Transgenic; Morpholines; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; Skin; Skin Abnormalities; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transforming Growth Factor alpha; Tyrphostins | 2006 |
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells | 2006 |
Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Amphiregulin; Amyloid Precursor Protein Secretases; Animals; Betacellulin; Calcium; Calmodulin; Chlorocebus aethiops; COS Cells; EGF Family of Proteins; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Glycoproteins; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Ligands; Membrane Proteins; Mice; Protein Structure, Tertiary; Recombinant Fusion Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2007 |
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Neoplasms; Peptides; Phenylmercuric Acetate; Protease Inhibitors; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vanadates | 2008 |
A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate 12-Lipoxygenase; Carcinogens; Cell Line; Cyclooxygenase Inhibitors; Epithelial Cells; Gene Silencing; Humans; Interleukin-8; Lipopolysaccharides; Lipoxygenase Inhibitors; MAP Kinase Signaling System; Mucin 5AC; Mucin-2; Mucin-5B; Mucus; Protein Transport; Respiratory Mucosa; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2012 |
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.
Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Angiotensin II; Blotting, Western; Cell Line, Tumor; EGF Family of Proteins; Enzyme Activation; Epidermal Growth Factor; Flow Cytometry; Glycoproteins; HEK293 Cells; Humans; Intercellular Signaling Peptides and Proteins; Isoenzymes; Jurkat Cells; Ligands; Phosphorylation; Protein Kinase C; Proteins; Proteolysis; RNA Interference; Serine; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2013 |
Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in a mouse model.
Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Animals; Disease Models, Animal; EGF Family of Proteins; Gene Expression Regulation; Humans; Mice; Psoriasis; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Stimulated release and functional activity of surface expressed metalloproteinase ADAM17 in exosomes.
Topics: A549 Cells; ADAM10 Protein; ADAM17 Protein; Amphiregulin; Amyloid Precursor Protein Secretases; Calcium Signaling; Carrier Proteins; Endothelial Cells; Enzyme Activation; Exosomes; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Membrane Microdomains; Membrane Proteins; Monocytes; Protein Transport; RNA Interference; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha | 2016 |