tetradecanoylphorbol acetate has been researched along with thromboxane a2 in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (16.67) | 18.7374 |
| 1990's | 37 (77.08) | 18.2507 |
| 2000's | 3 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eakins, KE; Kulkarni, P; Mufson, RA; Weinstein, IB | 1 |
| Jin, N; Packer, CS; Patterson, CE; Rhoades, RA | 1 |
| David, M; Griesmacher, A; Horvath, G; Mueller, MM; Weigel, G | 1 |
| Carroll, RC; Rubinstein, E; Urso, I | 1 |
| Lonigro, AJ; Sprague, RS; Stephenson, AH; Wurtz, MM | 1 |
| Arata, Y; Kume, S; Tada, S; Ui, M; Yatomi, Y | 1 |
| Azula, FJ; Font, J; Macarulla, JM; Marino, A; Nieva, N; Trueba, M | 1 |
| Ferro, TJ; Hocking, DC; Johnson, A | 1 |
| Hirata, M; Nakajima, M; Narumiya, S; Okuma, M; Ushikubi, F | 1 |
| Dubyak, GR; Dunn, MJ; Mené, P; Scarpa, A | 1 |
| Baudendistel, LJ; Bradley, JD; Dahms, TE; Webster, RO; Zanaboni, PB | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Dahms, TE; Lonigro, AJ; Sprague, RS; Stephenson, AH | 1 |
| Fujiwara, M; Nakajima, M; Narumiya, S; Okuma, M; Ushikubi, F; Yamamoto, M | 1 |
| Bienkowski, MJ; Petro, MA; Robinson, LJ | 1 |
| Kienast, J; Lenfers, B; van de Loo, J | 1 |
| Friesen, LL; Gerrard, JM; Israels, SJ; McCrea, JM; Robinson, P | 1 |
| Johnson, A | 1 |
| Katabami, F; Matsumiya, H; Matsuno, K | 1 |
| Bockman, RS; Honn, KV; Marnett, LJ | 1 |
| Matijevic-Aleksic, N; Sanduja, SK; Wang, LH; Wu, KK | 1 |
| Gaudette, DC; Holub, BJ; Kirkland, JB; Turini, ME | 1 |
| Bascands, JL; Bompart, G; Girolami, JP; Pecher, C; Rakotoarivony, J; Tack, JL | 1 |
| Bartolini, G; Belletti, B; Chiricolo, M; Davis, J; Minghetti, L; Orlandi, M; Spisni, E; Tomasi, V | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Björkholm, S; Edenius, C; Eriksson, I; Lindgren, JA; Näsman-Glaser, B; Tornhamre, S | 1 |
| Ali, S; Dorn, GW | 1 |
| Leoncini, G | 1 |
| Campbell, AK; Leikauf, GD; Myatt, L; Rapoport, RM; Roszell, N; Williams, SP | 1 |
| Murthy, M; Rao, GH; Reddy, S | 1 |
| Ermolenko, V; Kubatiev, A; Rudko, I | 1 |
| Armati, PJ; Constable, AL; Hartung, HP; Toyka, KV | 1 |
| McNicol, A; Nickolaychuk, BR | 1 |
| Colman, RW; Puri, RN | 1 |
| Chiu, L; Faung, ST; Wang, CT | 1 |
| Hu, YH; Offermanns, S; Simon, MI | 1 |
| Hashimoto, Y; Higashihara, M; Kurokawa, K; Satoh, H; Sunaga, S; Togo, M; Watanabe, T | 1 |
| Gaudette, DC; Holub, BJ; Mani, I | 1 |
| Eberhardt, RT; von Andrian, L; Ware, JA; Yokota, R; Yukawa, M | 1 |
| Hayaishi, O; Kanaoka, Y; Mahmud, I; Ueda, N; Urade, Y; Yamaguchi, H; Yamamoto, S; Yamashita, R | 1 |
| Ashton, S; Cook, J; Durando, M; Fernando, L; Halushka, P | 1 |
| Lockhart, LK; McNicol, A | 1 |
| Barsig, J; Nüsing, RM | 1 |
| Crews, BC; Daniel, TO; Liu, H; Marnett, LJ; Morrow, JD | 1 |
| Cogolludo, AL; Fajardo, S; Ibarra, M; Pérez-Vizcaíno, F; Tamargo, J | 1 |
| Bachschmid, M; Cosentino, F; De Paolis, P; Delli Gatti, C; Eto, M; Joch, H; Kouroedov, A; Lüscher, TF; Ullrich, V; van der Loo, B; Volpe, M | 1 |
| Goto, J; Hishinuma, T; Narahara, K; Suzuki, N; Tayama, R; Tomioka, Y; Tsukamoto, H | 1 |
2 review(s) available for tetradecanoylphorbol acetate and thromboxane a2
| Article | Year |
|---|---|
Platelet protein phosphorylation.
Topics: Actin Cytoskeleton; Blood Platelets; Blood Proteins; Calcium; Carrier Proteins; Cyclic AMP; Cytoplasmic Granules; Cytoskeleton; Diglycerides; Gelsolin; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lysophospholipids; Microfilament Proteins; Microtubules; Molecular Weight; Myosins; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1985 |
Prostaglandins and cancer: a review of tumor initiation through tumor metastasis.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; DNA; Epoprostenol; Female; Hematopoietic Stem Cells; Humans; Kidney; Male; Mutagens; Neoplasm Metastasis; Neoplasms; Oxidation-Reduction; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Skin; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1981 |
46 other study(ies) available for tetradecanoylphorbol acetate and thromboxane a2
| Article | Year |
|---|---|
Effects of phorbol ester tumor promoters in platelet aggregation and platelet production of cyclooxygenase products.
Topics: Animals; Arachidonic Acids; Biological Assay; Blood Platelets; In Vitro Techniques; Indomethacin; Phorbol Esters; Phorbols; Platelet Aggregation; Prostaglandin Endoperoxides; Rabbits; Tetradecanoylphorbol Acetate; Thromboxane A2; Vasoconstriction | 1979 |
Activated neutrophils alter contractile properties of the pulmonary artery.
Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contraction; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Artery; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase | 1992 |
Functional implications of cAMP and Ca2+ on prostaglandin I2 and thromboxane A2 synthesis by human endothelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Caffeine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Low concentrations of sodium azide specifically inhibit a thromboxane A2 pathway in human platelets.
Topics: Adenosine Diphosphate; Apyrase; Arachidonic Acid; Aspirin; Azides; Blood Platelets; Calcium; Collagen; Energy Metabolism; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Myosin-Light-Chain Kinase; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Secretory Rate; Serotonin; Sodium Azide; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Enhanced microvascular permeability of PMA-induced acute lung injury is not mediated by cyclooxygenase products.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Permeability; Dogs; In Vitro Techniques; Indomethacin; Leukocyte Count; Lung Diseases; Male; Methacrylates; Papaverine; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1992 |
Phosphorylation of the inhibitory guanine-nucleotide-binding protein as a possible mechanism of inhibition by protein kinase C of agonist-induced Ca2+ mobilization in human platelet.
Topics: Alkaloids; Amino Acid Sequence; Arginine Vasopressin; Blood Platelets; Blotting, Western; Calcium; Enzyme Activation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Intracellular Ca2+ mobilization and not calcium influx promotes phorbol ester-stimulated thromboxane A2 synthesis in human platelets.
Topics: Alkaloids; Blood Platelets; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Cytosol; Drug Synergism; Humans; Membrane Lipids; Phorbol 12,13-Dibutyrate; Phospholipids; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1992 |
Tumor necrosis factor-alpha primes pulmonary hemodynamic response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
Topics: Animals; Antioxidants; Drug Synergism; Guinea Pigs; Hemodynamics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Organ Size; Peroxidase; Platelet Activating Factor; Pulmonary Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1991 |
Purification and characterization of the human platelet TXA2/PGH2 receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Binding, Competitive; Blood Platelets; Bridged Bicyclo Compounds; Cell Membrane; Fatty Acids, Monounsaturated; Humans; Leukemia, Erythroblastic, Acute; Neoplasm Proteins; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1991 |
Regulation of cytosolic pH of cultured mesangial cells by prostaglandin F2 alpha and thromboxane A2.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine Vasopressin; Calcium; Cell Line; Cells, Cultured; Cytosol; Dinoprost; Fluoresceins; Fluorescent Dyes; Glomerular Mesangium; Humans; Hydrogen-Ion Concentration; Ionomycin; Kinetics; Male; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1991 |
Cyclooxygenase inhibition prevents PMA-induced increases in lung vascular permeability.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Body Fluids; Bridged Bicyclo Compounds, Heterocyclic; Capillary Permeability; Cyclooxygenase Inhibitors; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Male; Methacrylates; Prostaglandins; Pulmonary Circulation; Rabbits; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase; Vascular Resistance | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Thromboxane does not mediate pulmonary hypertension in phorbol ester-induced acute lung injury in dogs.
Topics: Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Dogs; Hypertension, Pulmonary; Lung; Lung Injury; Male; Methacrylates; Pulmonary Artery; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes; Vascular Resistance | 1990 |
Expression of thromboxane A2 receptor in cultured human erythroleukemia cells and its induction by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Bridged Bicyclo Compounds; Dactinomycin; Fatty Acids, Monounsaturated; Humans; Iodine Radioisotopes; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1989 |
Inhibition of thromboxane A synthesis in U937 cells by glucocorticoids. Lack of evidence for lipocortin 1 as the second messenger.
Topics: Aldosterone; Annexins; Cell Differentiation; Cycloheximide; Dactinomycin; Estradiol; Gene Expression Regulation; Glucocorticoids; Glycoproteins; Humans; Kinetics; Lipopolysaccharides; Testosterone; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured; Zymosan | 1989 |
Different pathways initiating arachidonic acid (AA) release/thromboxane (TxA2) formation in human platelets--studies with fluoride and phorbol ester.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Bucladesine; Calcium; Humans; In Vitro Techniques; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1989 |
PMA-induced pulmonary edema: mechanisms of the vasoactive response.
Topics: Animals; Blood Pressure; Capillary Permeability; Female; Guinea Pigs; Male; Papaverine; Perfusion; Pulmonary Edema; SRS-A; Tetradecanoylphorbol Acetate; Thiourea; Thromboxane A2; Vascular Resistance | 1988 |
[Cytoplasm free calcium ions as a second messenger].
Topics: Aequorin; Aminoquinolines; Blood Platelets; Calcium; Humans; Ions; Platelet Activating Factor; Platelet Aggregation; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1987 |
Differential expression of thromboxane A synthase and prostaglandin H synthase in megakaryocytic cell line.
Topics: Base Sequence; Blood Platelets; Blotting, Western; Cell Differentiation; Cell Line; Eicosanoids; Humans; Isoenzymes; Megakaryocytes; Microsomes; Molecular Sequence Data; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase | 1995 |
Correlation between platelet aggregation and dephosphorylation of a 68 kDa protein revealed through the use of putative PKC inhibitors.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Benzophenanthridines; Blood Proteins; Humans; Male; Molecular Weight; Naphthalenes; Phenanthridines; Phosphorus Radioisotopes; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1993 |
Bradykinin-induced in vitro contraction of rat mesangial cells via a B2 receptor type.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-2 Receptor Antagonists; Angiotensin II; Animals; Arginine Vasopressin; Bombesin; Bradykinin; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelins; Fatty Acids, Unsaturated; Glomerular Mesangium; Indomethacin; Kinetics; Naphthalenes; Neomycin; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Quinacrine; Rats; Receptors, Adrenergic, beta-2; Surface Properties; Tetradecanoylphorbol Acetate; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Possible involvement of prostaglandin H synthase-1 induction in the differentiation of U-937 cells.
Topics: Blotting, Western; Cell Differentiation; Cell Line; Cloning, Molecular; Cycloheximide; Dactinomycin; Dimethyl Sulfoxide; Enzyme Induction; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2 | 1995 |
Thromboxane A2-stimulated phospholipase D in osteoblast-like cells: possible involvement of PKC.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Division; Cell Line; Choline; DNA; Isoquinolines; Mice; Naphthalenes; Osteoblasts; Phospholipase D; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1995 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Regulation of leukotriene C4 synthase in human platelets via receptor-mediated mechanisms.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Blood Platelets; Chromatography, High Pressure Liquid; Collagen; Epoprostenol; Glutathione Transferase; GTP-Binding Proteins; Humans; Kinetics; Leukotriene C4; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Thrombin; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases | 1995 |
Patterns of tyrosine phosphorylation differ in vascular hypertrophy and hyperplasia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Hyperplasia; Hypertrophy; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Prostaglandin Endoperoxides, Synthetic; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Thromboxane A2; Type C Phospholipases; Tyrosine | 1994 |
N-ethylmaleimide inhibits platelet aggregation and potentiates hydrogen peroxide formation induced by thrombin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Ethylmaleimide; Humans; Hydrogen Peroxide; Platelet Activation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Modulation of phorbol ester-induced contraction by endogenously released cyclooxygenase products in rat aorta.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arachidonic Acid; Bridged Bicyclo Compounds, Heterocyclic; Epoprostenol; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Kinetics; Male; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins, Synthetic; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thromboxane A2; Time Factors | 1994 |
Differential effects of phorbol 12-myristate 13-acetate and diacylglycerols on thromboxane A2-independent phospholipase A2 activation in collage-stimulated human platelets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Blood Platelets; Calcimycin; Calcium; Collagen; Diglycerides; Enzyme Activation; Humans; Phospholipases A; Phospholipases A1; Phospholipases A2; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1994 |
Complement activation and neutrophil aggregation changes during haemodialysis.
Topics: Acrylic Resins; Adult; Arachidonic Acid; Calcimycin; Cell Aggregation; Cellulose; Complement Activation; Humans; Kidney Failure, Chronic; Membranes, Artificial; Middle Aged; Neutrophils; Renal Dialysis; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2 | 1993 |
Production of prostanoids by Lewis rat Schwann cells in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Half-Life; Interferon-gamma; Rats; Rats, Inbred Lew; Schwann Cells; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of collagen-induced platelet activation by arachidonyl trifluoromethyl ketone.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Collagen; Enzyme Inhibitors; Humans; Phospholipases A; Phospholipases A2; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1995 |
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Diphosphate; Blood Platelets; Calcimycin; Calcium; Cell Aggregation; Cell Size; Collagen; Cyclic AMP; Fibrinogen; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Time Factors | 1996 |
Platelet lysis and functional perturbation by 13-methyl myristate. The major fatty acid in Flavobacterium ranacida.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Animals; Blood Platelets; Cattle; Cell Membrane; Collagen; Fibrinogen; Flavobacterium; Humans; Microscopy, Electron, Scanning; Myristic Acids; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
Galpha12 and galpha13 are phosphorylated during platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; COS Cells; Enzyme Inhibitors; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Naphthalenes; Phosphorylation; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Blood Platelets; Eicosanoids; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Lysophospholipids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1996 |
Differential desensitization of thromboxane A2 receptor subtypes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Naphthalenes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1997 |
Prostaglandin D synthase in human megakaryoblastic cells.
Topics: Chromatography, Affinity; Glutathione; Humans; Intramolecular Oxidoreductases; Leukemia, Megakaryoblastic, Acute; Lipocalins; Megakaryocytes; Prostaglandin D2; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Cells, Cultured | 1997 |
Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity.
Topics: Arachidonic Acid; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Induction; Humans; Isoenzymes; Kinetics; Lipopolysaccharides; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Salmonella enteritidis; Tetradecanoylphorbol Acetate; Thromboxane A2; Transcription, Genetic | 1998 |
The phospholipase C inhibitor U73122 inhibits phorbol ester-induced platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Blood Proteins; Collagen; Enzyme Inhibitors; Estrenes; Fibrinogen; Humans; In Vitro Techniques; Microscopy, Electron; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrrolidinones; Serotonin; Tetradecanoylphorbol Acetate; Thromboxane A2; Type C Phospholipases; Vacuoles; Vasoconstrictor Agents | 1999 |
Induction of prostanoid, nitric oxide, and cytokine formation in rat bone marrow derived macrophages by activin A.
Topics: Activins; Animals; Bone Marrow Cells; Cyclooxygenase 2; Cytokines; Dinoprostone; Inhibins; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1999 |
Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Cornea; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelium, Vascular; Fatty Acids, Unsaturated; Fibroblast Growth Factor 2; Fibroblast Growth Factors; Humans; Hydrazines; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1999 |
Pulmonary artery vasoconstriction but not [Ca2+]i signal stimulated by thromboxane A2 is partially resistant to NO.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium Signaling; Enzyme Inhibitors; Indoles; Male; Maleimides; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Norepinephrine; Protein Kinase C; Pulmonary Artery; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Thromboxane A2; Vasoconstriction | 2001 |
High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species.
Topics: Cells, Cultured; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Epoprostenol; Gene Expression Regulation; Glucose; Humans; Intramolecular Oxidoreductases; Isoenzymes; Membrane Proteins; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane A2; Tyrosine; Up-Regulation | 2003 |
The induction of prostaglandin E synthase and upregulation of cyclooxygenase-2 by 9-cis retinoic acid.
Topics: Alitretinoin; Base Sequence; Blotting, Western; Cell Differentiation; DNA Primers; Humans; Intramolecular Oxidoreductases; Lipopolysaccharides; Prostaglandin-E Synthases; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Thromboxane A2; Tretinoin; U937 Cells; Up-Regulation | 2004 |