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tetradecanoylphorbol acetate and threonine

tetradecanoylphorbol acetate has been researched along with threonine in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199014 (15.05)18.7374
1990's41 (44.09)18.2507
2000's28 (30.11)29.6817
2010's10 (10.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, PD; Parker, PJ1
Adler, V; Kraft, AS; Polotskaya, A; Wagner, F1
Park, D; Rhee, SG1
Felder, S; LaVin, J; Schlessinger, J; Ullrich, A1
Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D1
Lammers, R; Pillay, TS; Siddle, K; Ullrich, A; Whittaker, J1
Akanuma, Y; Gotoh, Y; Hara, K; Kadowaki, T; Koshio, O; Momomura, K; Nishida, E; Tamemoto, H; Tobe, K; Ueki, K1
Bird, TA; Saklatvala, J1
Bird, TA; Dower, SK; Jackson, JL; Sims, JE; Woodward, A1
Bowen, S; Davis, RJ; Selva, E; Stanley, K1
Deuel, TF; Shawver, LK1
Decker, SJ; Ellis, C; Pawson, T; Velu, T1
Cao, L; Czech, MP; Lewis, RE; Perregaux, D1
Chen, WS; Gill, GN; Herbst, JJ; Lazar, CS; Lund, KA; Rosenfeld, MG; Walsh, BJ; Walton, GM; Welsh, JB; Wiley, HS1
Dobashi, K; Greene, MI; Weiner, DB1
Decker, SJ; Dorai, B; Russell, S1
Czech, MP; Davis, RJ4
Bertics, PJ; Cochet, C; Gill, GN; Weber, W1
Carpenter, CD; Chen, WS; Evans, RM; Gill, GN; Lazar, CS; Lin, CR; Rosenfeld, MG1
Boynton, AL; Raptis, L; Whitfield, JF1
Cooper, JA; King, CS1
Caron, MG; Cotecchia, S; DeBlasi, A; Leeb-Lundberg, LM; Lefkowitz, RJ1
Berent, E; Dull, TJ; Livneh, E; Prywes, R; Schlessinger, J; Ullrich, A1
Creutz, CE; Summers, TA1
Chinkers, M; Garbers, DL1
Ali, H; DuBose, RA; Haribabu, B; Richardson, RM; Snyderman, R; Tomhave, ED1
Lewis, RE; Sanderson, SD; Volle, DJ1
Eckhart, W; Schönthal, A; Srinivas, S1
Coghlan, MP; Pillay, TS; Siddle, K; Tavaré, JM1
Deng, T; Karin, M1
Blumberg, PM; Germano, P; Gomez, J; Kazanietz, MG; Rivera, J1
Capeau, J; Caron, M; Cherqui, G; Picard, J; Reynet, C; Wicek, D1
Decker, SJ; Pang, L; Saltiel, AR1
Ahn, J; Donner, DB; Rosen, OM1
Kim, T; Park, I; Payne, NS; Shin, J; Strominger, JL; Walsh, CT; Winkler, DG1
Bierer, BE; Hutchcroft, JE; Tsai, B1
Kalmar, GB; Oh, SS; Pelech, SL; Sanghera, JS; Siow, YL; Tai, G1
Benito, M; Lorenzo, M; Teruel, T; Valverde, AM1
Meighan-Mantha, RL; Riegel, AT; Wellstein, A1
Böl, GF; Bösel, A; Gros, C; Hülster, A; Pfeuffer, T1
Collard, JG; Elliott, CM; Exton, JH; Fleming, IN1
Avruch, J; Caudwell, FB; Cohen, P; Dalby, KN; Morrice, N1
Aboulafia-Etzion, S; Aharonovitz, O; Battler, A; Granot, Y; Leor, J1
Bai, M; Brown, EM; Lane, CR; Quinn, SJ; Trivedi, S; Yang, Y1
Bouin, AP; Fuchs, A; Grandvaux, N; Vignais, PV1
Edwards, AS; Faux, MC; Newton, AC; Scott, JD1
Cui, N; Jiang, C; Qu, Z; Zhu, G1
Bennett, V; Fukata, Y; Kaibuchi, K; Kawano, Y; Kinoshita, N; Matsuoka, Y; Matsuura, Y; Oshiro, N1
Andjelković, M; Cron, P; Hemmings, BA; Maira, SM; Parker, PJ1
Akashi, M; Miyata, Y; Nishida, E1
Chung, C; Han, JM; Kim, JH; Kim, Y; Lee, SD; Lee, TG; Oh, YS; Park, JB; Park, SK; Ryu, SH; Suh, PG; Yoo, JS1
Carter-Su, C; Herrington, J; Rui, L1
Lesslauer, W; Mary, JL; Tomás-Zuber, M1
Chaudhuri, S; Raha, S1
Clarke, H; Mullin, JM; Soler, AP1
Arman, M; Aussel, C; Calvo, J; Gimferrer, I; Lozano, F; Padilla, O; Places, L; Vilà, JM; Vives, J1
Benes, C; Soltoff, SP1
Herbert, TP; Proud, CG; Tee, AR1
Baudouin, E; Charpenteau, M; Ranjeva, R; Ranty, B1
Iijima, Y; Kuppuswamy, D; Laser, M; McDermott, PJ; Shiraishi, H; Sundaravadivel, B; Willey, CD; Xu, L1
el-Shemerly, M; Faisal, A; Hess, D; Nagamine, Y1
Díaz-Rodríguez, E; Esparís-Ogando, A; Montero, JC; Pandiella, A; Yuste, L1
Gaudreau, R; Le Gouill, C; Rola-Pleszczynski, M; Stankova, J; Venne, MH1
Iturrioz, X; Parker, PJ; Procyk, KJ; Srivastava, J1
Han, SW; Henrique-Silva, F; Machado-Santelli, GM; Pfister, SC1
Fowler, VM; Takemoto, DJ; Wagner, LM1
Babbitt, R; Busse, R; Fleming, I; Fulton, D; Lin, MI; Pritchard, KA; Sessa, WC1
Chen, JS; Exton, JH1
Craig, RW; Domina, AM; Gregory, MA; Hann, SR; Vrana, JA1
Allen-Baume, V; Ball, A; Cockcroft, S; Larijani, B; McDonald, N; Morgan, CP; Morrice, N; Murray-Rust, J; Sapkota, G; Segui, B; Skippen, A1
Doctor, RB; Finnigan, C; Fouassier, L; Gidey, E; Housset, C; Howell, KE; McWilliams, RR; Nichols, MT; Robin, H1
Burns, KA; Gray, JP; Leas, TL; Perdew, GH; Vanden Heuvel, JP1
Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K1
Caron, E; Lim, J; Patel, JC; Tsun, A; van Kooyk, Y; Wiedemann, A1
Blaser, N; Gutjahr, MC; Niggli, V; Rossy, J; Schlicht, D1
Hannun, YA; Idkowiak-Baldys, J; Kitatani, K1
Castañeda-Patlán, C; García, W; González-Aguilar, H; Lam, TT; Meléndez, L; Mendoza-Hernández, G; Robles-Flores, M1
Cao, J; Chen, W; Dai, B; Lin, D; Liu, L; Liu, Y; Ma, D; Sun, Y; Yu, H1
Chowdhury, I; Dodia, C; Feinstein, SI; Fisher, AB; Kazi, A; Manevich, Y; Pak, JH; Speicher, DW; Wu, Y1
Appella, E; Ashwell, JD; Mittelstadt, PR; Yamaguchi, H1
Bhamrah, M; Capasso, M; Cherny, VV; DeCoursey, TE; Dyer, MJ; Morgan, D; Musset, B1
Brown, KA; Docanto, M; Hunger, NI; Simpson, ER1
Dreyer, I; Gambale, F; Sato, A; Uozumi, N1
Ghosal, A; Said, HM; Subramanian, VS1
Akamatsu, T; Azlina, A; Hasegawa, T; Hosoi, K; Javkhlan, P; Yao, C1
Bannister, A; Gout, I; Hurd, PJ; Ismail, HM; Khalil, MI; Kouzarides, T1
D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J1
Matsumoto, M; Nakayama, KI; Sumimoto, H; Takeya, R; Yamamoto, A1
Craig, RW; Kasof, G; Nifoussi, SK; Ornstein, DL; Ratcliffe, NR; Strack, S1
Sonnenberg, A; Te Molder, L1

Other Studies

93 other study(ies) available for tetradecanoylphorbol acetate and threonine

ArticleYear
Activation of mitogen-activated protein (MAP) kinase by a MAP kinase-kinase.
    The Journal of biological chemistry, 1992, Jul-05, Volume: 267, Issue:19

    Topics: Adenosine; Autoradiography; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1992
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
    The Journal of biological chemistry, 1992, Aug-25, Volume: 267, Issue:24

    Topics: Cell Line; Chromatography, Affinity; Glutathione Transferase; Humans; Kinetics; Leukemia; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine

1992
Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP.
    Molecular and cellular biology, 1992, Volume: 12, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Chromatography, Affinity; Colforsin; Cyclic AMP; Epidermal Growth Factor; Immunoblotting; Kinetics; Molecular Sequence Data; Oncogene Proteins; Organ Specificity; PC12 Cells; Phosphorylation; Precipitin Tests; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Serine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases

1992
Kinetics of binding, endocytosis, and recycling of EGF receptor mutants.
    The Journal of cell biology, 1992, Volume: 117, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; DNA; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Mathematics; Mice; Mutagenesis, Site-Directed; Protein Binding; Tetradecanoylphorbol Acetate; Threonine; Transfection; Up-Regulation

1992
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
    The Biochemical journal, 1992, Apr-01, Volume: 283 ( Pt 1)

    Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins

1992
Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells.
    FEBS letters, 1991, Aug-19, Volume: 288, Issue:1-2

    Topics: Animals; Cell Line; Fibroblasts; Insulin; Insulin-Like Growth Factor I; Peptide Mapping; Phosphorylation; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection

1991
Insulin and 12-O-tetradecanoylphorbol-13-acetate activation of two immunologically distinct myelin basic protein/microtubule-associated protein 2 (MBP/MAP2) kinases via de novo phosphorylation of threonine and tyrosine residues.
    The Journal of biological chemistry, 1991, Dec-25, Volume: 266, Issue:36

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glycogen Synthase Kinase 3; Insulin; Molecular Sequence Data; Peptide Mapping; Phosphopeptides; Phosphorylation; Precipitin Tests; Protein Kinases; Swine; Tetradecanoylphorbol Acetate; Threonine; Trypsin; Tyrosine

1991
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
    The Journal of biological chemistry, 1990, Jan-05, Volume: 265, Issue:1

    Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine

1990
Phorbol ester induces phosphorylation of the 80 kilodalton murine interleukin 1 receptor at a single threonine residue.
    Biochemical and biophysical research communications, 1991, May-31, Volume: 177, Issue:1

    Topics: Amino Acid Sequence; Animals; Cell Line; Humans; Interleukin-1; Mice; Molecular Sequence Data; Molecular Weight; Phosphates; Phosphorylation; Phosphothreonine; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Threonine; Transfection

1991
Constitutive phosphorylation of the epidermal growth factor receptor blocks mitogenic signal transduction.
    The Journal of biological chemistry, 1991, Jan-15, Volume: 266, Issue:2

    Topics: Animals; Autoradiography; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Enzyme Activation; ErbB Receptors; Mitogens; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1991
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1990
Effects of substitution of threonine 654 of the epidermal growth factor receptor on epidermal growth factor-mediated activation of phospholipase C.
    The Journal of biological chemistry, 1990, Apr-25, Volume: 265, Issue:12

    Topics: Animals; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Inositol Phosphates; Kinetics; Mice; Mutation; Peptide Mapping; Phosphopeptides; Phosphorylation; Plasmids; Tetradecanoylphorbol Acetate; Threonine; Transfection; Type C Phospholipases

1990
Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C.
    Biochemistry, 1990, Feb-20, Volume: 29, Issue:7

    Topics: Amino Acids; Animals; Cells, Cultured; Chromatography, Affinity; Chromatography, High Pressure Liquid; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Humans; Mice; Peptide Mapping; Phosphopeptides; Phosphorylation; Placenta; Pregnancy; Protein Kinase C; Receptor, Insulin; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine

1990
Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation.
    The Journal of biological chemistry, 1990, Nov-25, Volume: 265, Issue:33

    Topics: Alanine; Animals; Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Ligands; Mice; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Threonine; Transfection

1990
Differential regulation of oncogenic and cellular p185 by serine/threonine kinases.
    DNA (Mary Ann Liebert, Inc.), 1989, Volume: 8, Issue:10

    Topics: Cell Division; Cell Line; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Membrane Proteins; Mutation; Oncogene Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine; Tetradecanoylphorbol Acetate; Threonine

1989
Mutation of a protein kinase C phosphorylation site in the erbB protein of avian erythroblastosis virus.
    Journal of virology, 1988, Volume: 62, Issue:10

    Topics: Alpharetrovirus; Animals; Avian Leukosis Virus; Cell Line; Cell Line, Transformed; Fibroblasts; Mutation; Oncogene Proteins v-erbB; Peptides; Phosphorylation; Precipitin Tests; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine; Viral Proteins

1988
Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:7

    Topics: Amino Acid Sequence; Carcinoma; Cells, Cultured; ErbB Receptors; Fibroblasts; Humans; Phorbols; Phosphopeptides; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Trypsin

1985
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:12

    Topics: Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Oncogenes; Peptide Fragments; Phorbols; Phosphorylation; Platelet-Derived Growth Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine

1985
Regulation of the epidermal growth factor receptor by phosphorylation.
    Journal of cellular biochemistry, 1985, Volume: 29, Issue:3

    Topics: Adenosine Triphosphate; Angiotensin II; Cell Membrane; Enzyme Activation; ErbB Receptors; Humans; Kinetics; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine

1985
Inhibition of the apparent affinity of the epidermal growth factor receptor caused by phorbol diesters correlates with phosphorylation of threonine-654 but not other sites on the receptor.
    The Biochemical journal, 1986, Jan-15, Volume: 233, Issue:2

    Topics: Amiloride; Amino Acids; Binding Sites; Carcinoma, Squamous Cell; Cell Line; ErbB Receptors; Humans; Phorbols; Phosphopeptides; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine

1986
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms.
    Cell, 1986, Mar-28, Volume: 44, Issue:6

    Topics: Alanine; Cell Line; DNA; Epidermal Growth Factor; ErbB Receptors; Humans; Methionine; Mutation; Phosphorylation; Protein Conformation; Protein Kinase C; Receptors, Cell Surface; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic

1986
Protein kinase C promotes the phosphorylation of immunoprecipitated middle T antigen from polyoma-transformed cells.
    Biochemical and biophysical research communications, 1986, May-14, Volume: 136, Issue:3

    Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Calcimycin; Cell Transformation, Viral; Densitometry; Mice; Molecular Weight; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphorylation; Polyomavirus; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates; Vanadium

1986
Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation.
    The Journal of biological chemistry, 1986, Aug-05, Volume: 261, Issue:22

    Topics: Cell Line; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1986
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
    The Journal of biological chemistry, 1987, Mar-05, Volume: 262, Issue:7

    Topics: Animals; Bradykinin; Cell Line; Drug Tolerance; Kinetics; Muscle, Smooth; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Phosphorylation; Prazosin; Receptors, Adrenergic, alpha; Serine; Tetradecanoylphorbol Acetate; Threonine

1987
Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts.
    The Journal of biological chemistry, 1987, May-15, Volume: 262, Issue:14

    Topics: Carcinogens; Cell Line; ErbB Receptors; Fibroblasts; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine

1987
Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor.
    Molecular and cellular biology, 1988, Volume: 8, Issue:6

    Topics: Animals; Base Sequence; Cell Line; Cloning, Molecular; Epidermal Growth Factor; ErbB Receptors; Mice; Mutation; Phosphorylation; Tetradecanoylphorbol Acetate; Threonine; Transfection

1988
Phosphorylation of a chromaffin granule-binding protein by protein kinase C.
    The Journal of biological chemistry, 1985, Feb-25, Volume: 260, Issue:4

    Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Annexins; Calcium; Carrier Proteins; Chromaffin Granules; Chromaffin System; Diglycerides; Membrane Proteins; Phosphatidylserines; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine

1985
Phorbol ester-induced threonine phosphorylation of the human epidermal growth factor receptor occurs within the EGF binding domain.
    Biochemical and biophysical research communications, 1984, Sep-17, Volume: 123, Issue:2

    Topics: Binding Sites; Cell Line; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Humans; Models, Biological; Neoplasms; Peptide Fragments; Phorbols; Phosphorylation; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Threonine; Trypsin

1984
Regulation of human interleukin-8 receptor A: identification of a phosphorylation site involved in modulating receptor functions.
    Biochemistry, 1995, Oct-31, Volume: 34, Issue:43

    Topics: Alkaloids; Amino Acid Sequence; Animals; Antigens, CD; Binding Sites; DNA, Complementary; Epitopes; Humans; Interleukin-8; Molecular Sequence Data; Mutation; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Receptors, Interleukin; Receptors, Interleukin-8A; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Threonine; Tumor Cells, Cultured; Up-Regulation

1995
Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor.
    The Journal of biological chemistry, 1994, Oct-21, Volume: 269, Issue:42

    Topics: Amino Acid Sequence; Base Sequence; Cells, Cultured; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine

1994
Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-11, Volume: 91, Issue:21

    Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Chloramphenicol O-Acetyltransferase; Gene Expression; Genes, jun; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; ras Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic; Transfection

1994
Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation.
    The Biochemical journal, 1994, Nov-01, Volume: 303 ( Pt 3)

    Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Cricetinae; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine

1994
c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK.
    Nature, 1994, Sep-08, Volume: 371, Issue:6493

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA-Binding Proteins; Epidermal Growth Factor; Humans; Mitogen-Activated Protein Kinase 1; Phosphorylation; Proline-Directed Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic; Ultraviolet Rays

1994
Phosphorylation of the gamma chain of the high affinity receptor for immunoglobulin E by receptor-associated protein kinase C-delta.
    The Journal of biological chemistry, 1994, Sep-16, Volume: 269, Issue:37

    Topics: Animals; Calcium; Endocytosis; Enzyme Activation; Indoles; Isoenzymes; Maleimides; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Receptors, IgE; Tetradecanoylphorbol Acetate; Threonine; Tumor Cells, Cultured

1994
Insulin receptor mutation at tyrosines 1162 and 1163 alters both receptor serine phosphorylation and desensitization.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:6

    Topics: Animals; CHO Cells; Cricetinae; Desensitization, Immunologic; Glycogen; Humans; Insulin; Mutation; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1994
Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells.
    The Biochemical journal, 1993, Jan-01, Volume: 289 ( Pt 1)

    Topics: 3T3 Cells; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1993
Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system.
    The Journal of biological chemistry, 1993, Apr-05, Volume: 268, Issue:10

    Topics: Animals; Baculoviridae; Cell Line; Cell-Free System; CHO Cells; Chromatography, High Pressure Liquid; Cloning, Molecular; Cricetinae; Electrophoresis, Gel, Two-Dimensional; Humans; Insulin; Moths; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Insulin; Tetradecanoylphorbol Acetate; Threonine

1993
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-01, Volume: 90, Issue:11

    Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; HeLa Cells; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine

1993
Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.
    The Journal of biological chemistry, 1996, Jun-07, Volume: 271, Issue:23

    Topics: Antibodies, Monoclonal; CD28 Antigens; Cell Line; Glycosylation; Humans; In Vitro Techniques; Lymphocyte Activation; Molecular Weight; Phosphorylation; Protein Kinase C; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Threonine

1996
Identification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase C.
    The Journal of biological chemistry, 1997, Mar-21, Volume: 272, Issue:12

    Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; COS Cells; Enzyme Activation; MAP Kinase Kinase Kinase 1; Mice; Molecular Sequence Data; p21-Activated Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine

1997
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection

1997
Differential regulation of extracellular signal-regulated kinase 1 and 2 activity during 12-O-tetradecanoylphorbol 13-acetate-induced differentiation of HL-60 cells.
    Experimental cell research, 1997, Aug-01, Volume: 234, Issue:2

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; HL-60 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myelin Basic Protein; Peptides; Phosphorylation; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

1997
Phorbol ester-induced sensitisation of adenylyl cyclase type II is related to phosphorylation of threonine 1057.
    Biochemical and biophysical research communications, 1997, Aug-18, Volume: 237, Issue:2

    Topics: Adenylyl Cyclases; Animals; Cell Line; COS Cells; Enzyme Activation; Humans; Mutagenesis, Site-Directed; Phosphorylation; Tetradecanoylphorbol Acetate; Threonine

1997
Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C.
    The Journal of biological chemistry, 1997, Dec-26, Volume: 272, Issue:52

    Topics: 3T3 Cells; Animals; Enzyme Activation; Fibroblasts; Guanine Nucleotide Exchange Factors; Lysophospholipids; Mice; Phosphorylation; Phosphothreonine; Protein Kinase C; Proteins; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetradecanoylphorbol Acetate; Threonine

1997
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK.
    The Journal of biological chemistry, 1998, Jan-16, Volume: 273, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Threonine

1998
Stimulation of 42/44 kDa mitogen-activated protein kinases by arginine vasopressin in rat cardiomyocytes.
    Biochimica et biophysica acta, 1998, Jan-02, Volume: 1401, Issue:1

    Topics: Amino Acid Sequence; Angiotensin II; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myelin Basic Protein; Myocardium; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vasoconstrictor Agents

1998
Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release.
    The Journal of biological chemistry, 1998, Aug-14, Volume: 273, Issue:33

    Topics: Calcium; Cell Line; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Mutagenesis, Site-Directed; Parathyroid Hormone; Phosphorylation; Protein Kinase C; Receptors, Calcium-Sensing; Receptors, Cell Surface; Staurosporine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases

1998
p40(phox) is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase. Implication of a protein kinase c-type kinase in the phosphorylation process.
    The Journal of biological chemistry, 1998, Nov-13, Volume: 273, Issue:46

    Topics: Amino Acid Substitution; Animals; Consensus Sequence; Enzyme Activation; HL-60 Cells; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Peptide Mapping; Phagocytes; Phosphoproteins; Phosphorylation; Protein Kinase C; Rabbits; Serine; Tetradecanoylphorbol Acetate; Threonine

1998
Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C betaII.
    The Journal of biological chemistry, 1999, Mar-05, Volume: 274, Issue:10

    Topics: Amino Acid Sequence; Animals; Carcinogens; Cattle; COS Cells; Isoenzymes; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Tetradecanoylphorbol Acetate; Threonine

1999
Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53.
    The Journal of biological chemistry, 1999, Apr-23, Volume: 274, Issue:17

    Topics: Animals; Female; Mutagenesis, Site-Directed; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine; Xenopus laevis

1999
Phosphorylation of adducin by Rho-kinase plays a crucial role in cell motility.
    The Journal of cell biology, 1999, Apr-19, Volume: 145, Issue:2

    Topics: Amino Acid Sequence; Animals; Calmodulin-Binding Proteins; Cell Line; Cell Membrane; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Dogs; GTP-Binding Proteins; GTPase-Activating Proteins; Hepatocyte Growth Factor; Humans; Intracellular Signaling Peptides and Proteins; Kidney; Models, Biological; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Phosphorylation; Protein Serine-Threonine Kinases; Recombinant Proteins; rho-Associated Kinases; Tetradecanoylphorbol Acetate; Threonine

1999
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase.
    Molecular and cellular biology, 1999, Volume: 19, Issue:7

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Biological Transport; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Humans; Mitogens; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Time Factors

1999
Molecular cloning and characterization of a novel member of the MAP kinase superfamily.
    Genes to cells : devoted to molecular & cellular mechanisms, 1999, Volume: 4, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Calcium-Calmodulin-Dependent Protein Kinases; Chromosome Mapping; Chromosomes, Human, Pair 14; Cloning, Molecular; COS Cells; DNA, Complementary; Enzyme Activation; Expressed Sequence Tags; Female; Gene Expression; Glucose; Humans; Male; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Conformation; Receptor for Advanced Glycation End Products; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Threonine; Tissue Distribution; Tyrosine

1999
Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites.
    Biochemistry, 1999, Aug-10, Volume: 38, Issue:32

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chromatography, High Pressure Liquid; Enzyme Activation; Fibroblasts; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phospholipase D; Phosphopeptides; Phosphorylation; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine

1999
SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade.
    The Journal of biological chemistry, 1999, Sep-10, Volume: 274, Issue:37

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Membrane; Intracellular Signaling Peptides and Proteins; Mutagenesis, Site-Directed; Nerve Growth Factors; PC12 Cells; Phosphorylation; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine

1999
Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor.
    The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31

    Topics: Amino Acid Sequence; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; HeLa Cells; Humans; Indoles; Insulin; Ionomycin; Isoquinolines; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha

2000
Inhibition and stimulation of growth of Entamoeba histolytica in culture: association with PKC activity and protein phosphorylation.
    Experimental parasitology, 2000, Volume: 95, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Culture Media; Down-Regulation; Entamoeba histolytica; Enzyme Inhibitors; Indoles; Maleimides; Marine Toxins; Okadaic Acid; Oxazoles; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine

2000
Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets.
    Journal of cell science, 2000, Volume: 113 ( Pt 18)

    Topics: Animals; Cell Fractionation; Cell Membrane Permeability; Enzyme Activation; Epithelial Cells; Immunoblotting; LLC-PK1 Cells; Membrane Proteins; Microscopy, Electron; Occludin; Phosphorylation; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Threonine; Tight Junctions

2000
Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; CD5 Antigens; Cell Membrane; Conserved Sequence; Cytoplasm; Diglycerides; Humans; Jurkat Cells; Peptide Fragments; Phosphorylation; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection

2001
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:6

    Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates

2001
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites.
    The Journal of biological chemistry, 2002, Mar-29, Volume: 277, Issue:13

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Cycle Proteins; Cell Line; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Threonine

2002
A 45-kDa protein kinase related to mitogen-activated protein kinase is activated in tobacco cells treated with a phorbol ester.
    Planta, 2002, Volume: 214, Issue:3

    Topics: Cells, Cultured; Cycloheximide; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Phosphorylation; Plant Proteins; Serine; Stress, Mechanical; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2002
c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.
    The Journal of biological chemistry, 2002, Jun-21, Volume: 277, Issue:25

    Topics: Adenoviridae; Animals; Blotting, Western; Butadienes; Cats; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Detergents; Dose-Response Relationship, Drug; Dual Specificity Phosphatase 1; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genes, Dominant; Insulin; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Nitriles; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Threonine; Time Factors

2002
Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.
    The Journal of biological chemistry, 2002, Aug-16, Volume: 277, Issue:33

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Insulin; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Proteins; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Threonine

2002
Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.
    Molecular biology of the cell, 2002, Volume: 13, Issue:6

    Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Binding Sites; Carrier Proteins; HeLa Cells; Humans; Membrane Proteins; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Receptor, trkA; Restriction Mapping; Retroviridae; Tetradecanoylphorbol Acetate; Threonine; Transfection

2002
Threonine 308 within a putative casein kinase 2 site of the cytoplasmic tail of leukotriene B(4) receptor (BLT1) is crucial for ligand-induced, G-protein-coupled receptor-specific kinase 6-mediated desensitization.
    The Journal of biological chemistry, 2002, Aug-30, Volume: 277, Issue:35

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; Casein Kinase II; Chlorocebus aethiops; COS Cells; DNA Primers; Enzyme Inhibitors; G-Protein-Coupled Receptor Kinases; Inositol Phosphates; Ligands; Models, Molecular; Polymerase Chain Reaction; Protein Conformation; Protein Kinase C; Protein Serine-Threonine Kinases; Receptors, Leukotriene B4; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Threonine; Transfection

2002
Phosphorylation is required for PMA- and cell-cycle-induced degradation of protein kinase Cdelta.
    The Biochemical journal, 2002, Nov-15, Volume: 368, Issue:Pt 1

    Topics: 3T3 Cells; Animals; Cell Cycle; Down-Regulation; Isoenzymes; Marine Toxins; Mice; Oxazoles; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; S Phase; Tetradecanoylphorbol Acetate; Threonine; Ubiquitin

2002
Mutational analyses of the signals involved in the subcellular location of DSCR1.
    BMC cell biology, 2002, Sep-11, Volume: 3

    Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine

2002
The interaction and phosphorylation of tropomodulin by protein kinase Calpha in N/N 1003A lens epithelial cells.
    Molecular vision, 2002, Oct-22, Volume: 8

    Topics: Animals; Blotting, Western; Carrier Proteins; Cells, Cultured; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Isoenzymes; Lens, Crystalline; Microfilament Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Rabbits; Tetradecanoylphorbol Acetate; Threonine; Transfection; Tropomodulin

2002
Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Adenosine Triphosphate; Animals; Arginine; Cattle; Cell Line; Cell Membrane; COS Cells; Embryo, Mammalian; Golgi Apparatus; Humans; Ionomycin; Kidney; Kinetics; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Transfection; Vascular Endothelial Growth Factor A

2003
Regulation of phospholipase D2 activity by protein kinase C alpha.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Indoles; Maleimides; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection

2004
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
    Oncogene, 2004, Jul-08, Volume: 23, Issue:31

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Carcinogens; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Okadaic Acid; Paclitaxel; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection

2004
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Animals; Binding Sites; Brain; Cell Membrane; Chromatography; Chromatography, High Pressure Liquid; COS Cells; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; HeLa Cells; HL-60 Cells; Humans; Isoelectric Focusing; Lipid Metabolism; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phospholipid Transfer Proteins; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection; Type C Phospholipases

2004
Protein kinase C regulates the phosphorylation and oligomerization of ERM binding phosphoprotein 50.
    Experimental cell research, 2005, May-15, Volume: 306, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Culture Media, Serum-Free; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Recombinant Fusion Proteins; Serine; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Threonine; Transfection

2005
Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C.
    Biochemistry, 2005, Aug-02, Volume: 44, Issue:30

    Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; Consensus Sequence; COS Cells; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Phosphorylation; PPAR alpha; Protein Kinase C; Pyrimidines; Rats; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection

2005
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
    Archives of biochemistry and biophysics, 2006, Feb-01, Volume: 446, Issue:1

    Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine

2006
Two distinct cytoplasmic regions of the beta2 integrin chain regulate RhoA function during phagocytosis.
    The Journal of cell biology, 2006, Mar-27, Volume: 172, Issue:7

    Topics: Actins; Amino Acid Sequence; Animals; CD18 Antigens; Cell Line, Tumor; Chlorocebus aethiops; Complement C3b; COS Cells; Erythrocytes; Guanosine Triphosphate; Macrophage-1 Antigen; Macrophages; Mice; Molecular Sequence Data; Mutation; Phagocytosis; Phagosomes; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Tetradecanoylphorbol Acetate; Threonine; Transfection

2006
Ezrin/moesin in motile Walker 256 carcinosarcoma cells: signal-dependent relocalization and role in migration.
    Experimental cell research, 2007, Apr-01, Volume: 313, Issue:6

    Topics: Androstadienes; Animals; Carcinogens; Carcinoma 256, Walker; Cell Movement; Cell Polarity; Cytoskeletal Proteins; Down-Regulation; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microfilament Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; rac1 GTP-Binding Protein; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection; Wortmannin

2007
Mechanism of inhibition of sequestration of protein kinase C alpha/betaII by ceramide. Roles of ceramide-activated protein phosphatases and phosphorylation/dephosphorylation of protein kinase C alpha/betaII on threonine 638/641.
    The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28

    Topics: Amino Acid Substitution; Carcinogens; Catalytic Domain; Cell Line, Tumor; Ceramides; Enzyme Activation; Enzyme Inhibitors; Fumonisins; Humans; Isoenzymes; Mutagenesis; Mutation, Missense; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Phosphatase 1; Protein Processing, Post-Translational; Protein Transport; Tetradecanoylphorbol Acetate; Threonine

2007
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
    Biochimica et biophysica acta, 2008, Volume: 1783, Issue:5

    Topics: Acetylglucosamine; Animals; Enzyme Activation; Epinephrine; Hepatocytes; Isoenzymes; Male; Mass Spectrometry; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Wistar; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2008
S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
    Journal of cellular physiology, 2009, Volume: 219, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antineoplastic Agents; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromones; Cyclin B; Enzyme Inhibitors; Humans; Megakaryocytes; Morpholines; Nocodazole; Phosphoproteins; Phosphorylation; Polyploidy; Protein Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sirolimus; Tetradecanoylphorbol Acetate; Threonine; TOR Serine-Threonine Kinases; Wortmannin

2009
Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.
    The Biochemical journal, 2009, May-01, Volume: 419, Issue:3

    Topics: Animals; Cell Extracts; Electrophoresis, Gel, Two-Dimensional; Endocytosis; Humans; Immunoprecipitation; Mitogen-Activated Protein Kinases; Mutation; Peroxiredoxin VI; Phospholipases A2; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Threonine

2009
T cell receptor-mediated activation of p38{alpha} by mono-phosphorylation of the activation loop results in altered substrate specificity.
    The Journal of biological chemistry, 2009, Jun-05, Volume: 284, Issue:23

    Topics: Adenosine Triphosphate; Animals; Enzyme Activation; Humans; Kinetics; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Antigen, T-Cell; Recombinant Proteins; Signal Transduction; Substrate Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2009
Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes.
    The Journal of biological chemistry, 2010, Feb-19, Volume: 285, Issue:8

    Topics: Amino Acid Substitution; Carcinogens; Cell Line; Enzyme Inhibitors; Humans; Indoles; Ion Channel Gating; Ion Channels; Leukocytes; Maleimides; Mutation, Missense; NADPH Oxidases; Phosphorylation; Protein Kinase C-delta; Respiratory Burst; Tetradecanoylphorbol Acetate; Threonine

2010
Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase.
    Breast cancer research and treatment, 2010, Volume: 123, Issue:2

    Topics: Active Transport, Cell Nucleus; Adipose Tissue; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Aromatase; Aromatase Inhibitors; Binding Sites; Breast; Chlorocebus aethiops; Colforsin; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Metformin; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Stromal Cells; Tetradecanoylphorbol Acetate; Threonine; Transcription Factors; Transfection

2010
Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.
    The FEBS journal, 2010, Volume: 277, Issue:10

    Topics: Amino Acid Substitution; Animals; Arabidopsis Proteins; Electrophysiological Phenomena; Naphthalenes; Oocytes; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Interaction Domains and Motifs; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection; Xenopus laevis

2010
Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation.
    Biochimica et biophysica acta, 2011, Volume: 1808, Issue:8

    Topics: Asparagine; Biological Transport; Biotin; Caco-2 Cells; Glycosylation; Humans; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Processing, Post-Translational; Retinal Pigment Epithelium; Structure-Activity Relationship; Symporters; Tetradecanoylphorbol Acetate; Threonine; Transfection; Tunicamycin

2011
Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:3

    Topics: Amino Acid Substitution; Animals; Antibodies; Antibody Specificity; Aquaporin 5; Calcimycin; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Detergents; Humans; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred ICR; Parotid Gland; Phosphorylation; Pilocarpine; Protein Kinase Inhibitors; Protein Transport; Salivary Glands; Signal Transduction; Submandibular Gland; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Transfection

2011
S6 kinase 2 is bound to chromatin-nuclear matrix cellular fractions and is able to phosphorylate histone H3 at threonine 45 in vitro and in vivo.
    Journal of cellular biochemistry, 2014, Volume: 115, Issue:6

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Differentiation; Cell Fractionation; Cell Line, Tumor; Chromatin; HEK293 Cells; Histones; HL-60 Cells; Humans; Mice; Middle Aged; Molecular Sequence Data; NIH 3T3 Cells; Nuclear Matrix; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Tetradecanoylphorbol Acetate; Threonine; U937 Cells

2014
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
    Molecular and cellular biology, 2013, Volume: 33, Issue:16

    Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine

2013
Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1.
    The FEBS journal, 2013, Volume: 280, Issue:20

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; Chromatography, Liquid; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Humans; NADPH Oxidase 1; NADPH Oxidases; Phosphorylation; Protein Binding; Protein Kinase C; Spectrometry, Mass, Electrospray Ionization; Superoxides; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate; Threonine

2013
Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.
    The Journal of biological chemistry, 2014, Aug-08, Volume: 289, Issue:32

    Topics: Binding Sites; Burkitt Lymphoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Marine Toxins; Myeloid Cell Leukemia Sequence 1 Protein; Okadaic Acid; Oxazoles; Phosphorylation; Protein Phosphatase 2; Proteolysis; Serine; Tetradecanoylphorbol Acetate; Threonine

2014
PKD2 and RSK1 Regulate Integrin β4 Phosphorylation at Threonine 1736.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Calcineurin; Calcium; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Epidermal Growth Factor; Gene Expression Regulation; Hemidesmosomes; Humans; Integrin alpha6beta4; Kalinin; Keratinocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plectin; Protein Kinase C-delta; Protein Structure, Tertiary; Pteridines; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; TRPP Cation Channels

2015