tetradecanoylphorbol acetate has been researched along with thiazoles in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (14.13) | 18.7374 |
| 1990's | 37 (40.22) | 18.2507 |
| 2000's | 36 (39.13) | 29.6817 |
| 2010's | 6 (6.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergstrand, H; Eriksson, T; Hallberg, A; Johansson, B; Karabelas, K; Michelsen, P; Nybom, A | 1 |
| Foreman, JC; Hayes, NA; McLeod, J | 1 |
| de Pont, JJ; Ederveen, AG; van Emst-de Vries, SE; Willems, PH | 1 |
| Karibe, H; Oishi, K; Uchida, MK | 1 |
| Canning, PC; Kehrli, ME; Stevens, MG | 1 |
| Ishibashi, S; Masayasu, H; Ohtsuka, T; Okamura, N; Wakamura, K | 1 |
| Boarder, MR; Jones, JA; Owen, PJ | 1 |
| Amiel, C; Cherqui, G; Escoubet, B; Garestier, MC | 1 |
| Baldari, CT; Donati, D; Macchia, G; Massone, A; Parente, L; Telford, JL | 1 |
| Hirst, JJ; Jenkin, G; Rice, GE; Thorburn, GD | 1 |
| Chow, SC; Jondal, M | 1 |
| Francis, LP; Singh, J | 1 |
| Goodrum, DD; Sachs, G; Wheeler, LA | 1 |
| David, JD; Faser, CR; Perrot, GP | 1 |
| Butler, RD; Evans, RL; McCrohan, CR | 1 |
| Bonne, C; Dornand, J; Emerit, I; Giroud, JP; Griswold, DE; Latour, E; Modat, G; Muller, A; Roch, M; Tissie, G | 1 |
| Bast, A; Leurs, R; Timmerman, H | 1 |
| Gavioli, R; Giuliani, A; Spisani, S; Traniello, S | 1 |
| Joseph, S; Kakkar, VV; Krishnamurthi, S | 1 |
| de Nucci, G; Gryglewski, RJ; Vane, JR; Warner, TD | 1 |
| Abney, NL; Maatta, EA; Perchellet, EM; Perchellet, JP | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Fitch, FW; Kim, DK; Nau, GJ | 1 |
| Anderson, RJ; Breckon, R; Burke, C; Dixon, BS | 1 |
| Fidelus, RK | 1 |
| Deli, E; Kiss, Z; Koeffler, HP; Kuo, JF; Pettit, GR; Shoji, M; Vogler, WR | 1 |
| Hayashi, M; Nomura, H; Oh-ishi, S; Tsushima, S; Yamaki, K | 1 |
| Aglietta, M; Arese, M; Bussolino, F; Camussi, G; Costamagna, C; Garbarino, G; Pescarmona, G; Sanavio, F; Silvagno, F; Soldi, R | 1 |
| Ansorge, S; Kähne, T; Neubert, K | 1 |
| Heiskanen, KM; Naarala, J; Savolainen, KM | 1 |
| Bousseau, A; Fauci, AS; Poli, G; Weissman, D | 1 |
| Brockman, JA; Hayes, SH; Lee, JS; Lowberger, LL; Silvia, WJ; Trammell, DS | 1 |
| Moog, C; Obert, G; Simon, G | 1 |
| Bäckström, LR; Chung, WB; Collins, MT; McDonald, J | 1 |
| Gay, JC | 1 |
| Fabian, I; Flidel, O; Gadish, M; Kletter, Y; Nagler, A; Slavin, S | 1 |
| Barcellini, W; Borghi, MO; Carbonelli, V; Del Papa, N; Fain, C; Gambini, D; La Rosa, L; Meroni, PL; Minonzio, F; Piona, A | 1 |
| McKay, C; Miller, A | 1 |
| Imamura, T; Kobayashi, M; Morioka, H; Sawa, T; Takada, Y; Takata, Y; Yang, GH | 1 |
| Bähr, M; Bock, M; Eckel, J; Kiehn, R; Spelleken, M; von Holtey, M | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Brown, ER; Dempsey, BK; Lew, DB; Malik, KU; Wright, HM | 1 |
| Inoue, I; Katayama, S; Komoda, T; Miyazaki, T; Negishi, K; Sonoda, M; Takahashi, K | 1 |
| Jimenez de Asua, L; Levy, CS; Rudland, PS; Sauane, M | 1 |
| Libby, P; Marx, N; Murphy, C; Plutzky, J; Sukhova, G | 1 |
| Ansorge, S; Faust, J; Kähne, T; Neubert, K | 1 |
| Hayakawa, A; Nakashima, I; Okamoto, T; Tajiri, H; Yokoyama, I | 1 |
| Djafarzadeh, S; Keller, H; Niggli, V | 1 |
| Burris, TP; Demarest, KT; Pelton, PD; Zhou, L | 1 |
| Cannady, SB; Combs, CK; Johnson, DE; Karlo, JC; Landreth, GE | 1 |
| Kim, JY; Lee, SH; Moon, CH; Woo, HG | 1 |
| Bell, D; McDermott, BJ | 1 |
| Gil, A; Gutiérrez, LM; Rueda, J; Viniegra, S | 1 |
| Kitahara, M; Naitoh, T; Tsuruzoe, N | 1 |
| Chandraratna, RA; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kim, S; Kintscher, U; Law, RE; Nagpal, S; Wakino, S | 1 |
| Eto, M; Hata, A; Horiuchi, S; Iwashima, Y; Kaku, K; Sano, H; Ushikubi, F | 1 |
| Calvo, JR; García-Mauriño, S; Guerrero, JM; Pozo, D | 1 |
| Brüne, B; Von Knethen A, A | 1 |
| Harris, SG; Phipps, RP | 1 |
| Bond, R; Cook, J; Gilkeson, G; Guyton, K; Halushka, P; Reilly, C | 1 |
| Akuzawa, N; Kurabayashi, M; Nagai, R; Oyama, Y | 2 |
| Ando, K; Chiba, Y; Fujita, T; Ogita, T | 1 |
| Holmes, TJ; Rainsford, KD | 1 |
| Clyne, CD; Duong, JH; Gong, C; Murata, Y; Rubin, GL; Simpson, ER; Speed, CJ | 1 |
| Barton, JA; Iyer, SS; Kusner, DJ; Rubenstein, PA; Wang, X; Wen, KK | 1 |
| Legrand, AB; Marigny, K; Martin-Chouly, CA; Pedrono, F; Saiag, B; Youmine, H | 1 |
| Qui, M; Smith, M; Stone, WL | 1 |
| Calvo, JR; Carrillo-Vico, A; García-Mauriño, S; Guerrero, JM | 1 |
| Allione, A; Beltramo, E; Buttiglieri, S; D'Alù, F; Lacaria, A; Pomero, F; Ponte, E; Porta, M | 1 |
| Bierhaus, A; Brodbeck, K; Häring, HU; Schleicher, ED; Weigert, C | 1 |
| Hu, XQ; Moradel, EM; Sun, H; Weight, FF; Zhang, L | 1 |
| Choi, IY; Hong, SH; Kim, HM; Kim, MS; Lee, SH; Shin, T | 1 |
| Aggarwal, BB; Singh, S; Takada, Y | 1 |
| Cook, JD; Ferrari, MB; Li, H; Spitzer, NC; Terry, M | 1 |
| Feng, YH; Li, XY; Liu, J; Ren, YX; Xu, JY; Yang, YF; Zhu, YN; Zou, JP | 1 |
| Collard, JG; de Lange, F; Figdor, CG; Nelissen, JM; van Emst-de Vries, SE; van Leeuwen, FN; Willems, PH; Zimmerman, AW | 1 |
| Bate, C; Langeveld, J; Williams, A | 1 |
| Borwege, S; Joyce, JN; Millan, MJ; Presgraves, SP | 1 |
| Chen, A; Chin, TY; Chueh, SH; Jin, JS; Ka, SM; Lee, HS; Lee, WH; Lin, YF; Sheu, LF; Yao, CW | 1 |
| Dilks, JR; Dvorak, AM; Feng, D; Flaumenhaft, R; Monahan-Earley, RA; Rozenvayn, N | 1 |
| Choi, IY; Hong, SH; Jeong, HJ; Kim, HM; Kim, SJ; Lee, KM; Park, RK | 1 |
| Bility, MT; Billin, AN; Gonzalez, FJ; Kim, DJ; Peters, JM; Willson, TM | 1 |
| Burmester, GR; Buttgereit, F; Dziurla, R; Erekul, K; Gaber, T; Grützkau, A; Häupl, T; Radbruch, A; Scheffold, A; Tripmacher, R; Tschirschmann, M | 1 |
| Bility, MT; Blazanin, N; Devlin-Durante, MK; Glick, AB; Gonzalez, FJ; Kang, BH; Kennett, MJ; Peters, JM; Ward, JM | 1 |
| Kim, H; Lee, S; Lee, WH; Mori, K; Park, HC; Park, JY; Suk, K | 1 |
| Kwon, TK; Lim, JH | 1 |
| Ferreira, ST; Jaureguiberry, MS; Prieto, ED; Ramella, NA; Rimoldi, OJ; Sanchez, SA; Schinella, GR; Tricerri, MA; Vela, ME | 1 |
| Dandekar, RD; Khan, MM | 1 |
| Hamilton, KD; Russell, FD | 1 |
| Klein, E; Lain, S; Madapura, HS; Nagy, N; Salamon, D; Wiman, KG | 1 |
| Barbosa, DS; Bonifácio, KL; Brinholi, FF; Casagrande, R; Farias, CC; Higachi, L; Moreira, EG | 1 |
92 other study(ies) available for tetradecanoylphorbol acetate and thiazoles
| Article | Year |
|---|---|
Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase.
Topics: Amino Acid Isomerases; Basophils; Calmodulin; Carbazoles; Carrier Proteins; Diacylglycerol Kinase; Histamine Release; Humans; Indole Alkaloids; Myosin-Light-Chain Kinase; Neutrophils; Peptidylprolyl Isomerase; Phosphotransferases; Protein Kinase C; Pyrimidinones; Superoxides; Tacrolimus; Tetradecanoylphorbol Acetate; Thiazoles | 1992 |
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells.
Topics: Animals; Ascitic Fluid; Calcium; Cyclohexanones; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Inbred Strains; Substance P; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Effects of phorbol ester and cholecystokinin on the intracellular distribution of protein kinase C in rabbit pancreatic acini.
Topics: Amylases; Animals; Cell Fractionation; Diacylglycerol Kinase; Kinetics; Pancreas; Phosphotransferases; Protein Kinase C; Pyrimidinones; Rabbits; Sincalide; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thiazoles | 1991 |
Involvement of protein kinase C in Ca(2+)-independent contraction of rat uterine smooth muscle.
Topics: Animals; Blotting, Western; Brain; Calcium; Electrophoresis, Polyacrylamide Gel; Female; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle, Smooth; Oxytocin; Protein Kinase C; Pyrimidinones; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles; Uterus | 1991 |
A colorimetric assay for quantitating bovine neutrophil bactericidal activity.
Topics: Analysis of Variance; Animals; Cattle; Cattle Diseases; Colchicine; Colony Count, Microbial; Colorimetry; Cytochalasin B; Interferon-gamma; Neutrophils; Recombinant Proteins; Serum Bactericidal Test; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1991 |
Mechanism for the inhibitory effect of a seleno-organic compound, Ebselen, and its analogues on superoxide anion production in guinea pig polymorphonuclear leukocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Enzyme Activation; Female; Guinea Pigs; Horses; Isoindoles; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Organoselenium Compounds; Protein Kinase C; Selenium; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Influence of phorbol esters, and diacylglycerol kinase and lipase inhibitors on noradrenaline release and phosphoinositide hydrolysis in chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cyclohexanones; Diacylglycerol Kinase; Hydrolysis; In Vitro Techniques; Lipoprotein Lipase; Norepinephrine; Phosphatidylinositols; Phosphotransferases; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
PKC and Pi deprivation modulate differently the ubiquitous Na-dependent Pi uptake in MDCK cells.
Topics: Adaptation, Physiological; Animals; Cell Line; Diglycerides; Kidney Tubules; Phosphates; Protein Kinase C; Pyrimidinones; Sodium; Tetradecanoylphorbol Acetate; Thiazoles | 1991 |
Induction of gene expression by IL-1 in NIH 3T3 cells. Possible requirement of protein kinase C activity and independence from arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Interleukin-1; Lipoxygenase Inhibitors; Mice; Protein Kinase C; Pyrimidinones; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1990 |
A central role for phosphoinositide hydrolysis in activating the lytic mechanism of human natural killer cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cytosol; Cytotoxicity, Immunologic; Diacylglycerol Kinase; Humans; Hydrolysis; Inositol Phosphates; Isoquinolines; Killer Cells, Natural; Neomycin; Phosphatidylinositols; Phosphotransferases; Piperazines; Protein Kinase C; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Effects of phorbol ester and related compounds on acetylcholine-evoked [3H]leucine-labelled protein secretion in permeabilized rat pancreatic acini.
Topics: Acetylcholine; Animals; Calcium; Cell Membrane Permeability; Cyclic GMP; Female; In Vitro Techniques; Inositol Phosphates; Male; Pancreas; Phospholipid Ethers; Polymyxin B; Proteins; Pyrimidinones; Rats; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Role of protein kinase C in the regulation of cytosolic Ca2+ in A431 cells: separation of growth factor and bradykinin pathways.
Topics: Alkaloids; Bradykinin; Calcium; Cytosol; Down-Regulation; Epidermal Growth Factor; Humans; Ionomycin; Manganese; Protein Kinase C; Pyrimidinones; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1990 |
Role of protein kinase C in chick embryo skeletal myoblast fusion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alprostadil; Animals; Calcium; Cell Fusion; Chick Embryo; Diglycerides; Enzyme Activation; Isoquinolines; Muscles; Piperazines; Protein Kinase C; Protein Kinases; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Tentacle contraction in Heliophrya erhardi (Suctoria): the role of inositol phospholipid metabolites and cyclic nucleotides in stimulus-response coupling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Chlorides; Ciliophora; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Inositol Phosphates; Lithium; Lithium Chloride; Muscle Contraction; Pyrimidinones; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thiazoles | 1988 |
2-(2-hydroxy-4-methylphenyl)aminothiazole hydrochloride as a dual inhibitor of cyclooxygenase/lipoxygenase and a free radical scavenger. 1st communication: in vitro studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cells, Cultured; Chromosome Aberrations; Cyclooxygenase Inhibitors; Free Radicals; Humans; In Vitro Techniques; Leukotrienes; Lipid Peroxidation; Lipoxygenase Inhibitors; Oxygen Consumption; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles | 1989 |
Inhibition of superoxide anion radical production by ebselen (PZ51) and its sulfur analogue (PZ25) in guinea pig alveolar macrophages.
Topics: Animals; Antioxidants; Azoles; Free Radicals; Guinea Pigs; In Vitro Techniques; Isoindoles; Macrophages; Male; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Organoselenium Compounds; Pulmonary Alveoli; Selenium; Superoxides; Tetradecanoylphorbol Acetate; Thiazoles | 1989 |
Protein kinase C mediates human neutrophil cytotoxicity.
Topics: Cytotoxicity, Immunologic; Diacylglycerol Kinase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases; Protein Kinase C; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles | 1987 |
Differential effects of the diacylglycerol kinase inhibitor R59022 on thrombin versus collagen-induced human platelet secretion.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; Diacylglycerol Kinase; Diglycerides; Dose-Response Relationship, Drug; Ethers; Glycerides; Humans; Ionomycin; Phosphoproteins; Phosphotransferases; Platelet Aggregation; Pyrimidinones; Serotonin; Tetradecanoylphorbol Acetate; Thiazoles; Thrombin | 1988 |
Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled.
Topics: Animals; Aorta; Biological Products; Cattle; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Gentamicins; Methylene Blue; Nitric Oxide; Pyrimidinones; Receptors, Cell Surface; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1988 |
Effects of diverse intracellular thiol delivery agents on glutathione peroxidase activity, the ratio of reduced/oxidized glutathione, and ornithine decarboxylase induction in isolated mouse epidermal cells treated with 12-O-tetradecanoylphorbol-13-acetate
Topics: Acetylcysteine; Animals; Cells, Cultured; Ditiocarb; Epidermis; Female; Glutathione; Glutathione Peroxidase; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1987 |
Thrombin and C-kinase activators potentiate calcium-stimulated arachidonic acid release in human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Diglycerides; Diterpenes; Drug Synergism; Humans; Isoquinolines; Phospholipids; Piperazines; Protein Kinase C; Pyrimidinones; Terpenes; Tetradecanoylphorbol Acetate; Thiazoles; Thrombin | 1987 |
Agents that mimic antigen receptor signaling inhibit proliferation of cloned murine T lymphocytes induced by IL-2.
Topics: Animals; Cells, Cultured; Clone Cells; Drug Combinations; Drug Synergism; Ethers; Growth Inhibitors; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mice, Inbred DBA; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1988 |
Phorbol esters inhibit adenylate cyclase activity in cultured collecting tubular cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Diglycerides; Kidney Tubules; Kidney Tubules, Collecting; Phorbol Esters; Protein Kinase C; Pyrimidinones; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiazoles; Vasopressins | 1988 |
The generation of oxygen radicals: a positive signal for lymphocyte activation.
Topics: Animals; Cell Line; Free Radicals; Glutathione; Lymphocyte Activation; Mercaptoethanol; Mice; Oxygen; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Thymoma; Tumor Cells, Cultured | 1988 |
Differential effects of various protein kinase C activators on protein phosphorylation in human acute myeloblastic leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.
Topics: Bryostatins; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Drug Resistance; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphorylation; Protein Kinase C; Proteins; Pyrimidinones; Terpenes; Tetradecanoylphorbol Acetate; Thiazoles | 1987 |
Suppression of phorbol myristate acetate-induced pleurisy by CV-3988, an antagonist of platelet-activating factor.
Topics: Animals; Male; Phospholipid Ethers; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles | 1986 |
Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.
Topics: Actins; Amino Acid Sequence; Antibodies; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cytoskeletal Proteins; Cytosol; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Ginkgolides; Humans; Isoenzymes; Kinetics; Lactones; Molecular Sequence Data; Naphthalenes; Peptides; Phospholipid Ethers; Platelet Activating Factor; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thiazoles; Vinculin | 1994 |
Enzymatic activity of DPIV/CD26 is involved in PMA-induced hyperphosphorylation of p56lck.
Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; src-Family Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles | 1995 |
The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes.
Topics: Calcium; Cell Membrane; Centrifugation, Density Gradient; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukocytes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1995 |
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
Topics: Cell Line; Chloramphenicol O-Acetyltransferase; Cytokines; Fluorescent Antibody Technique; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Reverse Transcriptase; HIV-1; Humans; Interleukin-6; Kinetics; Monocytes; Platelet Activating Factor; Pyridines; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA-Directed DNA Polymerase; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1993 |
Cellular mechanisms mediating the stimulation of ovine endometrial secretion of prostaglandin F2 alpha in response to oxytocin: role of phospholipase C and diacylglycerol.
Topics: Animals; Arginine Vasopressin; Diglycerides; Dinoprost; Endometrium; Enzyme Activation; Estrenes; Female; In Vitro Techniques; Indoles; Lactams; Lithium Chloride; Ovariectomy; Oxytocin; Pyrimidinones; Pyrrolidinones; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiazoles; Time Factors; Type C Phospholipases | 1994 |
Effects of glutathione precursors on human immunodeficiency virus replication.
Topics: Acetylcysteine; beta-Galactosidase; Cell Line; Colorimetry; Gene Expression Regulation, Viral; Glutathione; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; HIV Long Terminal Repeat; Homocysteine; Humans; Interleukin-6; Prodrugs; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Virus Replication | 1994 |
The (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium) colorimetric assay for the quantitation of Actinobacillus pleuropneumoniae cytotoxin.
Topics: Actinobacillus pleuropneumoniae; Animals; Cells, Cultured; Colorimetry; Coloring Agents; Cytotoxins; Immune Sera; Neutrophils; Regression Analysis; Reproducibility of Results; Swine; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1993 |
Mechanism and regulation of neutrophil priming by platelet-activating factor.
Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Effects of CAMPATH-1 antibodies on the functional activity of monocytes and polymorphonuclear neutrophils.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antigens, CD; Antigens, Neoplasm; Candida albicans; CD52 Antigen; Cell Death; Colorimetry; Flow Cytometry; Glycoproteins; Humans; Immunoglobulin G; Immunoglobulin M; Monocytes; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 1993 |
[Effect of pidotimod on the function of the human immune system: in vitro and ex vivo study].
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Antibody Formation; Chemotaxis, Leukocyte; Humans; Immune System; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-6; Lymphocyte Activation; Lymphocyte Subsets; Mitogens; Muromonab-CD3; Neutrophils; Phagocytosis; Phytohemagglutinins; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1993 |
Relationship among cellular diacylglycerol, sphingosine formation, protein kinase C activity, and parathyroid hormone secretion from dispersed bovine parathyroid cells.
Topics: Animals; Calcium; Cattle; Diacylglycerol Kinase; Diglycerides; Enzyme Inhibitors; Parathyroid Glands; Parathyroid Hormone; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Pyrimidinones; Sphingosine; Tetradecanoylphorbol Acetate; Thiazoles | 1996 |
Pioglitazone attenuates the inhibitory effect of phorbol ester on epidermal growth factor receptor autophosphorylation and tyrosine kinase activity.
Topics: Carcinoma, Squamous Cell; ErbB Receptors; Humans; Hypoglycemic Agents; Phosphorylation; Pioglitazone; Protein Kinase C; Protein Tyrosine Phosphatases; Receptor Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tumor Cells, Cultured | 1996 |
Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes.
Topics: 3-O-Methylglucose; Animals; Cells, Cultured; Chromans; Cytosol; Dose-Response Relationship, Drug; Glucose Transporter Type 1; Glucose Transporter Type 4; Heart Ventricles; Hypoglycemic Agents; Immune Sera; Immunoblotting; Isoenzymes; Lactic Acid; Male; Membrane Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Time Factors; Troglitazone | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Contribution of PKC to beta-hexosaminidase-induced airway smooth muscle proliferation.
Topics: Animals; beta-N-Acetylhexosaminidases; Cattle; Cell Count; Cell Division; Diacylglycerol Kinase; Enzyme Inhibitors; Hexosaminidase A; Insulin; Muscle, Smooth; Naphthalenes; Phenylisopropyladenosine; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Pyrimidinones; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles; Thymidine; Trachea | 1997 |
Troglitazone has a scavenging effect on reactive oxygen species.
Topics: Antioxidants; Chromans; Cytochrome c Group; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; Hydrogen Peroxide; Iron; Molecular Structure; Neutrophils; Pioglitazone; Reactive Oxygen Species; Spin Labels; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Troglitazone; Vitamin E; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Leukaemia inhibitory factor induces mitogenesis in Swiss 3T3 cells and selective enhancement via a variety of signalling events.
Topics: 3T3 Cells; Alprostadil; Animals; Diacylglycerol Kinase; Dinoprost; DNA; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Growth Inhibitors; Insulin; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Mitosis; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Pyrimidinones; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Transforming Growth Factor beta | 1997 |
Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro.
Topics: Arteriosclerosis; Blotting, Northern; Blotting, Western; Cell Line; Cells, Cultured; Chromans; Collagenases; Humans; Immunoenzyme Techniques; Macrophages; Matrix Metalloproteinase 9; Monocytes; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 1998 |
Early phosphorylation events induced by DPIV/CD26-specific inhibitors.
Topics: Calcium; CD3 Complex; Cyclic AMP; Dipeptidyl Peptidase 4; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Mitogens; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tyrosine | 1998 |
Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Apoptosis; Calcimycin; Cell Division; Ceramides; Cyclic AMP-Dependent Protein Kinases; DNA Fragmentation; Enzyme Inhibitors; fas Receptor; Female; Flow Cytometry; Humans; Isoquinolines; Ovarian Neoplasms; Protein Kinase C; Signal Transduction; Sphingomyelin Phosphodiesterase; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Stimulus-induced selective association of actin-associated proteins (alpha-actinin) and protein kinase C isoforms with the cytoskeleton of human neutrophils.
Topics: Actinin; Actins; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cells, Cultured; Chemotactic Factors; Cytochalasin D; Cytoskeleton; Enzyme Activation; Humans; Isoenzymes; Myosins; Neutrophil Activation; Neutrophils; Phosphoprotein Phosphatases; Polymers; Protein Kinase C; Protein Phosphatase 2; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Vinculin | 1999 |
PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes.
Topics: Adipocytes; Carrier Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Chromans; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Gene Expression; Humans; Kinetics; Monocytes; Myelin P2 Protein; Neoplasm Proteins; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Suppressor Proteins | 1999 |
Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Cell Differentiation; Chromans; Cyclooxygenase 2; Dinoprost; Genes, Reporter; Humans; Inflammation; Interleukin-6; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Microbodies; Microglia; Monocytes; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Augmentation effects of high glucose on endotoxin-induced nitric oxide production in murine macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aldehyde Reductase; Animals; Benzothiazoles; Cell Line; Drug Synergism; Enzyme Inhibitors; Glucose; Lipopolysaccharides; Macrophages; Mice; NAD; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phthalazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thiazoles | 1999 |
Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum.
Topics: Animals; Cattle; Cell Differentiation; Cell Survival; Chromans; Culture Media; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Fetal Blood; Glucose; Heart Ventricles; Hydrogen-Ion Concentration; Hypertrophy; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Male; Myocardium; Norepinephrine; Phenylalanine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
The F-actin cytoskeleton modulates slow secretory components rather than readily releasable vesicle pools in bovine chromaffin cells.
Topics: Actins; Adrenal Glands; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Cattle; Cell Membrane; Chromaffin Cells; Cytoplasmic Granules; Cytoskeleton; Electrophysiology; Enzyme Inhibitors; Exocytosis; Marine Toxins; Membrane Potentials; Microscopy, Electron; Oxazoles; Phosphorylation; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 2000 |
The effect of activation of peroxisome proliferator-activated receptor gamma (PPARgamma) on human monocyte function: PPARgamma ligands do not inhibit tumor necrosis factor-alpha release in human monocytic cell line THP-1.
Topics: Antineoplastic Agents; Carcinogens; Cell Survival; Cells, Cultured; Chromans; Humans; Hypoglycemic Agents; Ligands; Monocytes; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tumor Necrosis Factor-alpha | 2000 |
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Cell Movement; Chemokine CCL2; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Monocytes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2000 |
Advanced glycation end products-induced gene expression of scavenger receptors in cultured human monocyte-derived macrophages.
Topics: Blotting, Northern; CD36 Antigens; Cell Line; Cells, Cultured; Chromans; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Foam Cells; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Immunohistochemistry; Macrophages; Membrane Proteins; Microscopy, Fluorescence; Monocytes; NF-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Oxidized LDL; Receptors, Scavenger; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Scavenger Receptors, Class E; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Troglitazone; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Up-Regulation | 2000 |
Correlation between nuclear melatonin receptor expression and enhanced cytokine production in human lymphocytic and monocytic cell lines.
Topics: Acetamides; Adjuvants, Immunologic; Cell Membrane; Cell Nucleus; DNA Primers; Humans; Interleukin-2; Interleukin-6; Jurkat Cells; Lymphocytes; Melatonin; Monocytes; Phytohemagglutinins; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiosemicarbazones; U937 Cells | 2000 |
Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Escherichia coli; Genes, Reporter; Humans; Hypoglycemic Agents; Interferon-gamma; Lipopolysaccharides; Luciferases; Macrophages; Mice; Microbodies; Monocytes; NG-Nitroarginine Methyl Ester; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Respiratory Burst; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection | 2001 |
The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis.
Topics: Animals; Antigen Presentation; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Chromans; Flow Cytometry; Immunohistochemistry; In Situ Nick-End Labeling; Ionomycin; Ligands; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Specific Pathogen-Free Organisms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Topics: Animals; Cyclopentanes; DNA-Binding Proteins; Enzyme Activation; Epoprostenol; I-kappa B Proteins; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Nitric Oxide; Phosphorylation; Prostaglandin D2; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Thromboxane B2; Transcription Factors; Tumor Necrosis Factor-alpha | 2001 |
Troglitazone, a PPARgamma ligand, inhibits osteopontin gene expression in human monocytes/macrophage THP-1 cells.
Topics: Base Sequence; Cell Differentiation; Cells, Cultured; Chromans; Gene Expression Regulation; Humans; Ligands; Luciferases; Macrophages; Molecular Sequence Data; Monocytes; Osteopontin; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
PPARgamma ligands inhibit TNF-alpha-induced LOX-1 expression in cultured endothelial cells.
Topics: Animals; Arteriosclerosis; Cattle; Cells, Cultured; Chromans; Drug Antagonism; Endothelium; Immunohistochemistry; Pioglitazone; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Troglitazone; Tumor Necrosis Factor-alpha | 2001 |
Differential effects of non-genotoxic carcinogens and proliferating agents on cell growth, survival and apoptosis in hepatic cells in vitro.
Topics: Apoptosis; Carcinogens; Cell Count; Cell Division; Chlorobenzenes; Diethylhexyl Phthalate; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Hepatocytes; Human Growth Hormone; Humans; Hydroxyacetylaminofluorene; Mitogens; Nickel; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Cells, Cultured | 2001 |
PPARgamma ligand inhibits osteopontin gene expression through interference with binding of nuclear factors to A/T-rich sequence in THP-1 cells.
Topics: Animals; AT Rich Sequence; Cell Line; Chromans; COS Cells; Gene Expression; Gene Expression Regulation; Genes, Reporter; Humans; Hypoglycemic Agents; Ligands; Monocytes; Mutagenesis, Site-Directed; Nuclear Proteins; Osteopontin; Promoter Regions, Genetic; Protein Binding; Rabbits; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection; Troglitazone | 2002 |
Ligands for the peroxisomal proliferator-activated receptor gamma and the retinoid X receptor inhibit aromatase cytochrome P450 (CYP19) expression mediated by promoter II in human breast adipose.
Topics: Adipose Tissue; Aromatase; Base Sequence; Chromans; Colforsin; Female; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Regulation of phospholipase D activity by actin. Actin exerts bidirectional modulation of Mammalian phospholipase D activity in a polymerization-dependent, isoform-specific manner.
Topics: Actins; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytosol; Deoxyribonuclease I; Depsipeptides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Macromolecular Substances; Magnesium Chloride; Mammals; Marine Toxins; Peptides, Cyclic; Phalloidine; Phospholipase D; Protein Isoforms; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; U937 Cells | 2002 |
Modulation of endothelial permeability by 1-O-alkylglycerols.
Topics: Albumins; Animals; Aorta; Calcimycin; Cell Membrane Permeability; Cells, Cultured; Coloring Agents; Diglycerides; Endothelium, Vascular; Glycerol; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2002 |
Lipopolysaccharide enhances the cytotoxicity of 2-chloroethyl ethyl sulfide.
Topics: Adjuvants, Immunologic; Animals; Cell Death; Cell Line; Chemical Warfare Agents; Cytokines; Drug Synergism; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mustard Gas; Propidium; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor.
Topics: Acetamides; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-2; Lymphocytes; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiosemicarbazones | 2003 |
Effects of protein kinase C inhibition and activation on proliferation and apoptosis of bovine retinal pericytes.
Topics: Animals; Apoptosis; Cattle; Cell Count; Cell Division; DNA; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Flow Cytometry; Glucose; Isoenzymes; Mesylates; Pericytes; Protein Kinase C; Pyrroles; Retina; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2003 |
c-Fos-driven transcriptional activation of transforming growth factor beta-1: inhibition of high glucose-induced promoter activity by thiazolidinediones.
Topics: Animals; Cells, Cultured; Chromans; Glucose; Hydrogen Peroxide; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Swine; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1; Troglitazone | 2003 |
Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C.
Topics: Actins; Animals; Binding Sites; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cytoskeleton; Electrophysiology; Enzyme Activation; Humans; Ions; Mice; Microscopy, Fluorescence; Mutation; Oocytes; Phalloidine; Phosphorylation; Point Mutation; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; RNA, Complementary; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Time Factors; Tumor Cells, Cultured; Xenopus; Xenopus laevis | 2003 |
The Oriental medicine "Cool-Cool (Cool-X-A)" inhibits inflammatory cytokine production and migration in mast cells.
Topics: Cell Movement; Cell Survival; Cells, Cultured; Chemotaxis; Cytokines; Depression, Chemical; Drugs, Chinese Herbal; Humans; Interleukin-8; Mast Cells; Reverse Transcriptase Polymerase Chain Reaction; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Tumor Necrosis Factor-alpha | 2004 |
Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
Topics: Active Transport, Cell Nucleus; Alkaline Phosphatase; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell-Free System; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; In Situ Nick-End Labeling; Interleukin-1; Lipopolysaccharides; Microscopy, Phase-Contrast; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Peptide Fragments; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor RelA; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation | 2004 |
Calcium transients regulate patterned actin assembly during myofibrillogenesis.
Topics: Actin Cytoskeleton; Actins; Animals; Azepines; Bridged Bicyclo Compounds, Heterocyclic; Calcium Signaling; CapZ Actin Capping Protein; Connectin; Cytochalasin D; Depsipeptides; Microfilament Proteins; Muscle Development; Muscle Proteins; Myosin-Light-Chain Kinase; Myosins; Naphthalenes; Peptides, Cyclic; Protein Kinases; Sarcomeres; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Xenopus | 2004 |
Differential regulation of resveratrol on lipopolysacchride-stimulated human macrophages with or without IFN-gamma pre-priming.
Topics: Antigen-Presenting Cells; Antigens, CD; B7-2 Antigen; Cell Death; Cell Differentiation; Cell Survival; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-12; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Phenotype; Recombinant Proteins; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Necrosis Factor-alpha | 2004 |
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.
Topics: Activated-Leukocyte Cell Adhesion Molecule; Alkaloids; Antibodies, Monoclonal; Benzophenanthridines; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Cell Adhesion; Cytochalasin D; Cytoskeleton; Dose-Response Relationship, Drug; Down-Regulation; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; K562 Cells; Microscopy, Fluorescence; Phenanthridines; Phosphorus Radioisotopes; Protein Kinase C; Protein Kinase C-alpha; Retroviridae; rho GTP-Binding Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 2004 |
Manipulation of PrPres production in scrapie-infected neuroblastoma cells.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Blotting, Western; Brain; Carcinogens; Cell Count; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidase K; Enzyme-Linked Immunosorbent Assay; Glycosylation; Humans; Interleukin-6; Mice; Microglia; Neuroblastoma; Prions; PrPSc Proteins; Scrapie; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tretinoin | 2004 |
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.
Topics: 1-Methyl-4-phenylpyridinium; Antibodies; Benzothiazoles; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Line; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enzyme Inhibitors; Humans; Neuroblastoma; Neurons; Neuroprotective Agents; Oxazines; Pramipexole; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetradecanoylphorbol Acetate; Thiazoles; Tretinoin | 2004 |
IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cell Size; Cells, Cultured; Enzyme Activators; Enzyme Inhibitors; Glomerular Mesangium; Immunoblotting; Immunoglobulin A; Ionomycin; Ionophores; Isoenzymes; Mice; Muscle Contraction; Phenanthridines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2004 |
The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion.
Topics: Actins; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Cell Degranulation; Cytochalasins; Cytoplasmic Granules; Cytoskeleton; Humans; Kinetics; Microscopy, Electron, Transmission; Peptide Fragments; SNARE Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines; Vesicular Transport Proteins | 2005 |
Cyclooxygenase-2 inhibitor SC-236 [4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1-pyrazol-1-l] benzenesulfonamide] suppresses nuclear factor-kappaB activation and phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase,
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Immunohistochemistry; Ionophores; JNK Mitogen-Activated Protein Kinases; Luciferases; Mast Cells; Membrane Proteins; Microscopy, Confocal; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stimulation, Chemical; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2005 |
PPARbeta/delta selectively induces differentiation and inhibits cell proliferation.
Topics: Animals; Calcium; Calcium Signaling; Cell Differentiation; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; In Vitro Techniques; Keratinocytes; Ligands; Mice; Mice, Knockout; Models, Biological; Peroxidase; PPAR-beta; Tetradecanoylphorbol Acetate; Thiazoles | 2006 |
Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production.
Topics: Adenosine Triphosphate; Arthritis, Rheumatoid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; CD4-Positive T-Lymphocytes; Cell Proliferation; Cytochromes b; Cytokines; Electron Transport Complex III; Gene Expression; Gene Expression Profiling; Glucose; Glycolysis; Humans; Hypoxia; Ionomycin; Joint Capsule; Lymphocyte Activation; Methacrylates; Osteoarthritis; Oxidative Phosphorylation; Oxygen Consumption; Tetradecanoylphorbol Acetate; Thiazoles | 2008 |
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis.
Topics: Acetone; Animals; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Enzyme Activation; Female; Keratinocytes; Ligands; Mice; Mice, Mutant Strains; PPAR delta; PPAR-beta; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazoles | 2008 |
Lipocalin-2 is an autocrine mediator of reactive astrocytosis.
Topics: Amides; Analysis of Variance; Animals; Animals, Newborn; Annexin A2; Apoptosis; Astrocytes; Autocrine Communication; Brain; Cell Movement; Cells, Cultured; Embryo, Nonmammalian; Flow Cytometry; Green Fluorescent Proteins; Mice; Mice, Inbred ICR; Nitrites; Nitroprusside; Penicillamine; Phagocytes; Propidium; Pyridines; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transfection; Tumor Necrosis Factor-alpha; Zebrafish | 2009 |
Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity.
Topics: Antineoplastic Agents; Blotting, Western; Cell Nucleus; Chemokine CCL2; Coloring Agents; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Humans; Luciferases; NF-kappa B; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; U937 Cells | 2010 |
Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis.
Topics: Amyloid; Anilino Naphthalenesulfonates; Animals; Apolipoprotein A-I; Atherosclerosis; Benzothiazoles; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Heparin; Humans; Hydrogen-Ion Concentration; Hypochlorous Acid; Matrix Metalloproteinase 12; Neutrophil Activation; Oxidation-Reduction; Protein Binding; Protein Folding; Protein Stability; Protein Structure, Quaternary; Protein Structure, Secondary; Proteolysis; Solvents; Tetradecanoylphorbol Acetate; Thiazoles; Tryptophan | 2011 |
Involvement of histamine receptors in SAPK/JNK phosphorylation.
Topics: Animals; Betahistine; Female; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; MAP Kinase Signaling System; Methylhistamines; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Spleen; Tetradecanoylphorbol Acetate; Thiazoles; Tumor Necrosis Factor-alpha | 2012 |
Nutrient deprivation increases vulnerability of endothelial cells to proinflammatory insults.
Topics: Calcium Channels; Cell Adhesion; Coculture Techniques; Culture Media, Serum-Free; Electron Transport Chain Complex Proteins; Human Umbilical Vein Endothelial Cells; Humans; Methacrylates; Neutrophils; Oxidative Stress; Ruthenium Red; Superoxides; Tetradecanoylphorbol Acetate; Thiazoles; Tumor Necrosis Factor-alpha | 2014 |
cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytotoxicity, Immunologic; Down-Regulation; Feedback, Physiological; Humans; Imidazoles; Immunity; Lymphocyte Activation; Models, Biological; Piperazines; Proto-Oncogene Proteins c-myc; Receptors, Notch; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53 | 2016 |
Clozapine and olanzapine are better antioxidants than haloperidol, quetiapine, risperidone and ziprasidone in in vitro models.
Topics: Antioxidants; Antipsychotic Agents; Benzodiazepines; Biphenyl Compounds; Clozapine; Free Radical Scavengers; Haloperidol; Humans; Models, Biological; Neutrophil Activation; Neutrophils; Olanzapine; Picrates; Piperazines; Quetiapine Fumarate; Reactive Oxygen Species; Risperidone; Tetradecanoylphorbol Acetate; Thiazoles | 2016 |