tetradecanoylphorbol acetate has been researched along with thapsigargin in 266 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (4.14) | 18.7374 |
| 1990's | 166 (62.41) | 18.2507 |
| 2000's | 77 (28.95) | 29.6817 |
| 2010's | 10 (3.76) | 24.3611 |
| 2020's | 2 (0.75) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Alkhalaf, B; Ballejo, G; Gong, Y; Molnar, P; Murphy, LC; Murphy, LJ | 1 |
| Schönthal, A | 1 |
| Clementi, E; Fasolato, C; Meldolesi, J; Pozzan, T; Scheer, H; Zacchetti, D | 1 |
| Doll, S; Hertting, G; Schobert, A; Seregi, A | 1 |
| Balla, T; Catt, KJ; Clark, AJ; Jones, MR | 1 |
| Gilfillan, AM; Lin, P | 1 |
| Catt, KJ; Iida, T; Krsmanovic, LZ; Mellon, PL; Merelli, F; Stojilković, SS; Zheng, L | 1 |
| Blevins, GT; Wagner, AC; Williams, JA; Yule, DI | 1 |
| Gardner, JD; Jensen, RT; Metz, DC; Mrozinski, JE; Patto, RJ; Turner, RJ | 1 |
| Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ | 1 |
| Crichton, CA; Currie, S; Hallam, C; Jackson, CG; Smith, GL; Wakelam, MJ | 1 |
| Johnson, AL; Tilly, JL | 1 |
| Briscoe, CP; Cook, SJ; Wakelam, MJ | 1 |
| Levine, L; Watanabe, M | 1 |
| Blondel, B; Capponi, AM; Chardonnens, D; Johnson, EI; Kem, DC; Koshida, H; Lang, U; Vallotton, MB | 1 |
| Balla, T; Holló, Z; Spät, A; Várnai, P | 1 |
| Chew, CS; Petropoulos, AC | 1 |
| Fürstenberger, G; Hanke, B; Marks, F; Thastrup, O | 1 |
| Enslen, H; Lenormand, P; Magun, BE; Muldoon, LL; Rodland, KD | 1 |
| Christensen, SB; Fujiki, H; Hakii, H; Nakayasu, M; Scheuer, PJ; Suganuma, M; Sugimura, T; Tahira, T | 1 |
| Hansen, HS; Jacobsen, S; Jensen, B | 1 |
| Foder, B; Scharff, O; Thastrup, O | 1 |
| Fujiki, H; Hirota, M; Suganuma, M; Sugimura, T; Suguri, H; Takagi, K; Yoshizawa, S | 1 |
| Fujiki, H | 1 |
| Fujiki, H; Iizuka, T; Ishimura, Y; Kano, S; Sugimura, T | 1 |
| Bjerrum, PJ; Christensen, SB; Knudsen, JB; Linnebjerg, H; Thastrup, O | 1 |
| Christensen, SB; Fujiki, H; Hirasawa, N; Ohuchi, K; Sugawara, T; Sugimura, T; Tsurufuji, S; Watanabe, M | 2 |
| Fujiki, H; Hirasawa, N; Ohuchi, K; Ozeki, T; Tsurufuji, S; Watanabe, M | 1 |
| Christensen, SB; Dickmeiss, E; Foder, B; Hofmann, B; Jacobsen, KD; Langhoff, E; Møller, J; Ryder, LP; Scharff, O; Thastrup, O | 1 |
| De Pont, JJ; Van Emst-de Vries, SE; Willems, PH | 1 |
| Lloret, S; Martínez, J; Moreno, JJ | 1 |
| Camp, RD; Greaves, MW; Hartfield, PJ | 1 |
| Matsui, S; Matsumoto, Y; Tanimura, A; Tojyo, Y | 1 |
| Fenton, M; Kay, JE | 1 |
| Falet, H; Rendu, F | 1 |
| Alfonso, A; Botana, LM; Botana, MA; Louzao, MC; Vieytes, MR | 1 |
| Berridge, MJ; Bootman, MD; Jenkins, AL; Stone, SR | 1 |
| Thurston, G; Turner, D | 1 |
| Fetz, I; Fölsch, UR; Höcker, M; Meyer-Alber, A; Schmidt, WE; Waschulewski, IH | 1 |
| Musgrave, IF; Schultz, G; Seifert, R | 1 |
| Bolton, TB; Prestwich, SA | 1 |
| Durand, J; Marmy, N | 1 |
| Smallridge, RC; Tsokos, GC; Vassilopoulos, D | 1 |
| Farber, JL; Hoek, JB; Thomas, AP; Wang, X | 1 |
| Drouhault, R; Roudbaraki, MM; Vacher, P | 1 |
| Barańska, J; Chaban, V; Czarny, M; Sabała, P | 1 |
| Reich, H; Sei, Y | 1 |
| Akaike, N; Uneyama, C; Uneyama, H | 1 |
| Goetz, FW | 1 |
| Komatsu, M; McDermott, AM; Sharp, GW | 1 |
| Sharp, GW; Tang, SH; Yaney, GC | 1 |
| Beltrán, LM; DiGiovanni, J; Kiguchi, K; Rho, O; You, J | 1 |
| Biden, TJ; Browne, CL; Darby, K; Herzog, H; Schmitz-Peiffer, C; Selbie, LA; Shine, J | 1 |
| Abello, J; Bosshard, A; Chayvialle, JA; Saifia, S | 1 |
| Geiszt, M; Káldi, K; Ligeti, E; Szeberényi, JB | 1 |
| Farber, JL; Savory, J; Serroni, A; Snyder, JW | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K; Shirakawa, M | 1 |
| Brock, TA; White, CR | 1 |
| Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y | 1 |
| Anwer, MS | 1 |
| Bissonnette, M; Brasitus, TA; Khare, S; Tien, XY; Wali, RK; Wilson, DM | 1 |
| Conroy, LA; Hallam, TJ; Merritt, JE | 1 |
| Matsumoto, Y; Tanimura, A; Tojyo, Y | 1 |
| Alexandre, A; Cavallini, L | 1 |
| Brooker, G; Mattie, M; Spiegel, S | 1 |
| Aussel, C; Bernard, A; Breittmayer, JP; Deckert, M | 1 |
| Bode, HP; Göke, B | 1 |
| Nordeen, SK | 1 |
| Gosling, M; Poyner, DR; Smith, JW | 1 |
| Golinski, P; Neusser, M; Rahn, KH; Spieker, C; Tepel, M; Zhu, Z; Zidek, W | 1 |
| Doubell, AF; Thibault, G | 1 |
| Gali, HU; Gao, XM; Perchellet, EM; Perchellet, JP | 1 |
| Jaconi, ME; Krause, KH; Lew, DP; Monod, A | 1 |
| Endo, Y; Furuya, S; Ito, T; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Benistant, C; Gustavsson, L; Hoek, JB; Moehren, G; Rubin, R; Torres-Marquez, ME | 1 |
| Törnquist, K | 2 |
| Marfella, C; Romani, A; Scarpa, A | 1 |
| Ekokoski, E; Törnquist, K | 1 |
| Brooker, G; Debernardi, MA; Munshi, R | 1 |
| Marcus, CB; Pfeifer, RW; Yoon, HL | 1 |
| Brüne, B; Ullrich, V; Von Appen, F; Wu, XB | 1 |
| Anwer, MS; Engelking, LR; Grüne, S | 1 |
| Chen, SL; Lenormand, P; Magun, BE; Pribnow, D; Rodland, KD | 1 |
| Bullock, AJ; Murphy, CT; Westwick, J | 1 |
| Haimovich, B; Ji, P; Kaneshiki, N | 1 |
| Kimball, BC; Mulholland, MW | 1 |
| Hennings, H; Li, L; Lowry, DT | 1 |
| Chang, EY; Fewtrell, C; Rivera, J; Wolfe, PC | 1 |
| Loh, TT; Zhu, WH | 1 |
| Chik, CL; Ho, AK; Ogiwara, T | 1 |
| Cardone, MH; Mennitt, PA; Mochly-Rosen, D; Mostov, KE; Silver, RB; Smith, BL | 1 |
| Holsapple, MP; Karras, JG; Kramer, CM; Matulka, RA; Morris, DL | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 1 |
| Azuma, A; Hashimoto, Y; Hioki, E; Iwasaki, S; Kobayashi, Y; Miyachi, H | 1 |
| Putney, JW; Ribeiro, CM | 1 |
| Berchtold, MW; Döbbeling, U | 1 |
| Colangelo, AM; Mocchetti, I; Pani, L | 1 |
| Akaike, N; Takahashi, M; Uneyama, C; Uneyama, H | 1 |
| Chung, HT; Jun, CD; Kang, SS; Kim, HM; Lee, SY; Park, YC; Yoon, HJ | 1 |
| Balasubramanyam, M; Gardner, JP | 1 |
| Baeuerle, PA; Pahl, HL | 1 |
| Escobales, N; Gonzalez, O; Martinez, J | 1 |
| Glass, PS; Xuan, YT | 1 |
| Beaver, J; Waring, P | 1 |
| Ahnadi, CE; Dupuis, G; Payet, MD | 1 |
| Komatsu, M; Schermerhorn, T; Sharp, GW; Straub, SG | 1 |
| Knol, EF; Lie, WJ; Mul, FP; Roos, D; Verhoeven, AJ | 1 |
| Kankaanranta, H; Kosonen, O; Luomala, M; Moilanen, E | 1 |
| Marriott, I; Mason, MJ | 1 |
| Kawai, N; McCarron, RM; Spatz, M | 1 |
| Rebel, G; Tchoumkeu-Nzouessa, GC | 1 |
| Kim, KT; Kim, YK; Song, SK; Suh, BC | 1 |
| Belloni-Olivi, L; Bressler, JP; Forman, S; Goldstein, GW | 1 |
| Akasaka, R; Ikebuchi, H; Sawada, J; Teshima, R | 1 |
| Abud-Mendoza, C; González-Amaro, R; Portales-Pérez, D; Sánchez-Armáss, S | 1 |
| Chen, M; Heiman, AS | 1 |
| Beaven, MA; Hirasawa, N; Zhang, C | 1 |
| Fischer, R; Häussinger, D; Schliess, F | 1 |
| Mue, S; Niki, H; Ohuchi, K; Watanabe-Kobayashi, M; Yamada, M; Yamashita, M | 1 |
| Born, JL; Burchiel, SW; Lauer, FT; Mounho, BJ; Romero, DL | 1 |
| Earp, HS; Graves, LM; Li, X; Yu, H | 1 |
| Alonso, A; Bayon, Y; Garcia-Sancho, J; Hernandez, M; Leslie, C; Nieto, ML; Nuñez, L; Sanchez Crespo, M | 1 |
| Bergmann, J; Brandt, U; Gartzke, J; Lange, K | 1 |
| Daulhac, L; Kowalski-Chauvel, A; Pradayrol, L; Seva, C; Vaysse, N | 1 |
| Akbarali, HI; Hrnjez, BJ; Matthews, JB; Mayol, JM; Smith, JA; Song, JC | 1 |
| Fürstenberger, G; Goldman, R; Meller, R; Moshonov, S; Seger, R; Zor, U | 1 |
| Bundey, R; Duman, RS; Iredale, PA | 1 |
| Dufy, B; Horvath, G; Lorsignol, A; Taupignon, A | 1 |
| Choudhury, Q; Flower, RJ; Willmott, NJ | 1 |
| Jensen, RT; Kusui, T; Tsuda, T | 1 |
| Banasiak, M; Barańska, J; Czarny, M; Stepkowski, D; Wiktorek-Wójcik, M | 1 |
| Kojima, M; Miyakawa, T; Ui, M | 1 |
| Bychkov, R; Chapman, J; Haller, H; Luft, FC; Luft, UC; McCarron, DA; Roullet, CM; Roullet, JB; Xue, H | 1 |
| Assmann, G; Nofer, JR; Seedorf, U; Tepel, M; Walter, M; Zidek, W | 1 |
| Distelhorst, CW; Qi, XM; Simonson, M | 1 |
| Gylfe, E; Liu, YJ | 1 |
| Benton, HP; Loredo, GA | 1 |
| Dugué, B; Ekokoski, E; Törnquist, K | 1 |
| Braciale, VL; Esser, MT; Fuller, CL; Gullo, CA; Haverstick, DM | 1 |
| Bazer, FW; Hansen, PJ; Mirando, MA; Thatcher, WW; Tysseling, KA | 1 |
| Earp, HS; Haskill, JS; Hunter, D; Li, X; Morris, J | 1 |
| Benito, E; Blazquez, E; Bosch, MA | 1 |
| Krutetskaia, NI; Krutetskaia, ZI; Lebedev, OE | 1 |
| Gawdi, G; Lewis, JG; Misra, UK; Pizzo, SV | 1 |
| Barnhart, DC; Mulholland, MW; Sarosi, GA; Turner, DJ | 1 |
| Bookstein, C; Chang, EB; McSwine, RL; Musch, MW; Rao, M; Xie, Y | 1 |
| Bei, L; Hu, T; Qian, ZM; Shen, X | 1 |
| Anegawa, NJ; Bacskai, BJ; Grant, ER; Lynch, DR; Pleasure, DE | 1 |
| Björnsson, OG; Bourgeois, CS; Gibbons, GF | 1 |
| Choi, SY; Kim, KT; Song, SK | 1 |
| Cantin, G; Craig, FF; Durick, K; Knapp, T; Negulescu, PA; Rockenstein, E; Sanders, P; Whitney, M; Zlokarnik, G | 1 |
| Bosch, RR; de Pont, HH; Emst-de Vries, SE; Joep, J; Patel, AM; Sleutels, F; Smeets, RL; Willems, PH | 1 |
| Daniel, WG; Garlichs, CD; Mügge, A; Zhang, H | 1 |
| Alfonso, A; Botana, LM; Botana, MA; Vieytes, MR | 1 |
| Furniss, MJ; Haberer, J; Miller, SC; Venkatachalam, U | 1 |
| Bobryshev, AIu; Skok, VI; Voĭtenko, SV | 1 |
| Dugué, B; Titievsky, A; Törnquist, K; Tuominen, R; Vainio, P | 1 |
| Bendia, E; Benedetti, A; Bolognini, L; Di Sario, A; Feliciangeli, G; Jezequel, AM; Orlandi, F; Ridolfi, F; Svegliati Baroni, G | 1 |
| Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
| Kim, YP; Lee, SH; Lim, SS; Ohuchi, K; Ryu, N; Shin, KH; Yamada, M | 1 |
| Bei, L; Hu, TH; Qian, ZM; Shen, X | 1 |
| Botana, LM; Vieites, JM; Vieytes, MR; Vilariño, N | 1 |
| Kozawa, O; Shinoda, J; Tokuda, H; Uematsu, T | 1 |
| Barańska, J; Czajkowski, R | 1 |
| Chen, BC; Lin, LL; Lin, WW | 1 |
| Fewtrell, C; Kuchtey, J | 1 |
| Ahrén, B; Karlsson, S | 1 |
| Järvilehto, M; Piispala, J; Serpi, R; Vähäkangas, K | 1 |
| Libermann, TA; Petersen, N; Prinz, S; Sallmann, S; Schneider, A; Schwaninger, M; Spranger, M | 1 |
| Ferris, HA; García, LJ; Jensen, RT; Tapia, JA | 1 |
| Hoek, JB; Strayer, DS; Thomas, AP; White, MK | 1 |
| Carpentier, JL; Cartier, L; Foti, M; Krause, KH; Lew, DP; Piguet, V; Trono, D | 1 |
| Florio, T; Giordano, G; Giusti, M; Schettini, G; Thellung, S; Valenti, S | 1 |
| Li, S; Pestka, JJ; Yang, GH | 1 |
| Brunner, HR; Domenighetti, A; Marsh, DJ; Palmiter, RD; Pedrazzini, T; Pellieux, C; Sauthier, T | 1 |
| Dartt, DA; Hodges, RR; Sergheraert, C; Zoukhri, D | 1 |
| Drexler, HG; Meyer, C; Steube, KG | 1 |
| Hayden, MR; Mujumdar, VS; Tyagi, SC | 1 |
| DeFelice, LJ; Jayanthi, LD; Montalvo, J; Wilson, JJ | 1 |
| Hirasawa, N; Kobayashi, Y; Murakami, A; Ohuchi, K; Oikawa, S; Shiraishi, M | 1 |
| Hayakawa, T; Ishiguro, H; Kitagawa, M; Mizuno, N; Naruse, S | 1 |
| Buxbaum, JD; Corfas, G; Peschon, JJ; Rio, C | 1 |
| Belinsky, GS; Tashjian, AH | 1 |
| Klemm, J; Rådmark, O; Samuelsson, B; Werz, O | 1 |
| Kondo, I | 1 |
| Agarwal, C; Balasubramanian, S; Banks, E; Dubyak, GR; Eckert, RL; Efimova, T; Welter, J | 1 |
| Fujimura, A; Harada, K; Kawaguchi, A; Ohmori, M; Sugimoto, K; Tsuruoka, S | 1 |
| Lin, WW; Wen, HC | 1 |
| Hymer, TK; Katz, MS; Lifschitz, MD; Yeh, CK; Zhang, BX | 1 |
| Bird, GS; Hosoki, E; McKay, RR; Putney, JW; Ribeiro, CM | 1 |
| Chen, LW; Jan, CR | 1 |
| Fong, CW; Lin, SC; Neo, SY; Zhang, Y | 1 |
| Cohen, DM; Rodland, KD; Roullet, JB; Yang, XY; Zhang, Z; Zhao, H | 1 |
| Endo, Y; Fukasawa, H; Hashimoto, Y; Shudo, K; Yamaguchi, M | 1 |
| Gomez, P; Himpens, B; Vereecke, J | 1 |
| Boland, R; Buitrago, C; de Boland, AR; Morelli, S | 1 |
| Nikkari, T; Roy, S; Sen, CK; Siljamäki, T; Viita, H; Ylä-Herttuala, S | 1 |
| Billardon, C; Carvajal-Gonzalez, S; Gompel, A; Kandouz, M; Lombet, A; Rostène, W; Zujovic, V | 1 |
| Grama, L; Lustyik, G; Somogyi, B; Visegrády, A | 1 |
| Botana, LM; de la Rosa, LA; Vieytes, MR; Vilariño, N | 1 |
| Blauvelt, A; Davis, DA; Moses, AV; Orenstein, JM; Overwijk, WW; Rinderknecht, AS; Yarchoan, R; Zoeteweij, JP | 1 |
| Chien, EJ; Hsieh, DJ; Wang, JE | 1 |
| Bosco, D; Gonelle-Gispert, C; Halban, PA; Rouiller, DG; Wollheim, CB | 1 |
| Ellis, CA; Kouklis, P; Malik, AB; Minshall, RD; Sandoval, R; Tiruppathi, C | 1 |
| Chadee, K; De Waele, C; Yu, Y | 1 |
| Braileanu, GT; Hu, J; Mirando, MA | 1 |
| Han, C; Lei, B; Zhang, Y | 1 |
| Balaji, RA; Balasubramanyam, M; Mohan, V; Subashini, B | 1 |
| Badou, A; Cassar, G; Druet, P; Foucras, G; Guéry, JC; Lagrange, D; Leclerc, C; Moreau, M; Paulet, P; Pelletier, L; Savignac, M | 1 |
| Díaz, P; Lucas, M | 1 |
| Bosch, RR; De Pont, JJ; Harris, AB; van Emst-de Vries, SE; Willems, PH | 1 |
| Bouteau, F; Brouillard, F; Dellis, O; Gangloff, SC; Guenounou, M; Paulais, M; Rona, JP; Teulon, J; Tondelier, D | 1 |
| Chandrasekhar, S; Halladay, DL; Martin, TJ; Miles, RR; Onyia, JE; Thirunavukkarasu, K | 1 |
| Engedal, N; Korkmaz, CG; Saatcioglu, F | 1 |
| Li, HF; Lo, YK; Shen, AY; Wu, SN | 1 |
| Garcha, K; Steele, JE; Sun, D | 1 |
| Jenks, BG; Lieste, JR; Roubos, EW; Scheenen, WJ; Schoenmakers, TJ; Willems, PH | 1 |
| Fukuta, H; Kito, Y; Suzuki, H; Yamamoto, Y | 1 |
| Beaven, MA; Chahdi, A; Choi, WS; Fraundorfer, PF; Kim, YM | 1 |
| Katz, MS; Lifschitz, MD; Ma, X; Yeh, CK; Zhang, BX; Zhu, MX | 1 |
| Matthews, JB; Rangachari, PK; Song, JC | 1 |
| Ban, HS; Kim, YP; Lee, S; Ohuchi, K; Shin, KH; Yamaki, K | 1 |
| Borron, PJ; Doyle, C; McHeyzer-Williams, MG; Mostaghel, EA; Walsh, ES; Wright, JR | 1 |
| Hughes, TR; Irvine, SA; Mead, JR; Ramji, DP; Singh, NN | 1 |
| Chen, YZ; Huang, XY; Qiu, J; Wang, CG | 1 |
| Bragado, MJ; García-Marin, LJ; Jensen, RT; Pace, A; Tapia, JA | 1 |
| Bhugra, P; Dhalla, NS; Rathi, S; Xu, YJ | 1 |
| Hirashima, N; Kato, N; Nakanishi, M | 1 |
| Fabbro, M; Nair, SV; Raftos, DA | 1 |
| Hermoso, M; Olivero, P; Quest, AF; Riveros, A; Stutzin, A; Torres, R | 1 |
| Bahra, P; Estacion, M; Gosling, M; Li, S; Poll, C; Schilling, WP; Sinkins, WG; Westwick, J | 1 |
| Bialasiewicz, P; Dudkiewicz, B; Nowak, D; Wlodarczyk, A | 1 |
| Bristulf, J; Owman, C; Sabirsh, A | 1 |
| Bankers-Fulbright, JL; Bartemes, KR; Kephart, GM; Kita, H; O'Grady, SM | 1 |
| Fortin, GD; Martel, P; Michel, FJ; Trudeau, LE; Yeomans, J | 1 |
| Beaven, MA; Peng, Z | 1 |
| Bauer, RA; Pores-Fernando, AT; Wurth, GA; Zweifach, A | 1 |
| Akimoto, T; Koyama, T; Kusumi, I; Suzuki, K | 1 |
| Di Jeso, B; Elia, MG; Marsigliante, S; Muscella, A; Storelli, C; Treglia, AS; Ulianich, L | 1 |
| Debnam, ES; Goestemeyer, AK; Marks, J; Srai, SK; Unwin, RJ | 1 |
| Ding, X; Murray, PA; Yang, M | 1 |
| Gaur, S; Grybko, MJ; Pores-Fernando, AT; Zweifach, A | 1 |
| Lorenzo, PI; Saatcioglu, F | 1 |
| Deng, T; Ge, Y; Lu, M; Zhang, L; Zheng, X | 1 |
| Ahmed, A; Mukherjee, S; Nandi, D | 1 |
| Arnoldussen, YJ; Danielsen, HE; Lorenzo, PI; Maelandsmo, GM; Pretorius, ME; Risberg, B; Saatcioglu, F; Waehre, H | 1 |
| McBean, GJ; Murphy, A; Vines, A | 1 |
| Bressan, GC; Gava, LM; Kobarg, J; Lanza, DC; Quaresma, AJ; Ramos, CH | 1 |
| Hantash, BM; Reeves, JP; Thomas, AP; Turner, JD | 1 |
| Engelmann, P; Németh, P; Opper, B | 1 |
| Huang, X; Lai, X; Lu, X; Ye, Y; Zeng, X; Zeng, Y; Zhang, Y | 1 |
| Maeyama, K; Nugroho, AE; Riyanto, S; Sukari, MA | 1 |
| Raghuwanshi, SK; Rosendorff, A; Rowe, DT; Taylor, GM; Wadowsky, RM | 1 |
| Culp, DJ; Evans, RL; Zhang, Z | 1 |
| Hessari, NM; Lee, I; Pan, L; Wu, X; Xu, J; Zhang, X; Zhao, D | 1 |
| Chueh, SH; Lin, KC; Liu, PS; Peng, PY | 1 |
| Jensen, RT; Nuche-Berenguer, B; Sancho, V | 1 |
| Albarrán, L; Dionisio, N; Lopez, JJ; Rosado, JA; Salido, GM; Smani, T | 1 |
| Dahariya, S; Gutti, RK; Kovuru, N; Pallepati, A; Raghuwanshi, S; Sharma, DS | 1 |
| Andrabi, SA; Dang, N; Hossain, MI; Li, Z; Parant, JM; Scott, HE; Thomas, HR; Wang, J; Yeo, NCF | 1 |
2 review(s) available for tetradecanoylphorbol acetate and thapsigargin
| Article | Year |
|---|---|
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C5a; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine Release; Humans; Hypersensitivity; Interleukin-3; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nasal Lavage Fluid; Phorbol Esters; Platelet Activating Factor; Prostaglandin D2; Receptors, IgE; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Thapsigargin; Tryptases | 1996 |
Serine/threonine protein kinases synergistically regulate phospholipase D1 and 2 and secretion in RBL-2H3 mast cells.
Topics: Animals; Antigens; Carbachol; Cholera Toxin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Mast Cells; Phospholipase D; Protein Serine-Threonine Kinases; Rats; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 2002 |
264 other study(ies) available for tetradecanoylphorbol acetate and thapsigargin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Phorbol esters differentially regulate the expression of insulin-like growth factor-binding proteins in endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Blotting, Northern; Calcimycin; Carrier Proteins; Cell Division; Cycloheximide; Endometrial Neoplasms; Enzyme Activation; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Kinetics; Protein Kinase C; RNA, Messenger; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1992 |
Gene regulation by Ca2+ ATPases. Evidence from the use of thapsigargin, a specific inhibitor of intracellular membrane Ca2+ ATPases.
Topics: 3T3 Cells; Animals; Blotting, Northern; Calcium-Transporting ATPases; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Mice; Poly A; RNA; RNA, Messenger; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Receptor-activated Ca2+ influx. Two independently regulated mechanisms of influx stimulation coexist in neurosecretory PC12 cells.
Topics: Animals; Atropine; Bradykinin; Caffeine; Calcium; Calcium-Transporting ATPases; Carbachol; Fura-2; Imidazoles; Inositol 1,4,5-Trisphosphate; Neurons; PC12 Cells; Receptors, Cell Surface; Ryanodine; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 1992 |
Functionally diverse purinergic P2Y-receptors mediate prostanoid synthesis in cultured rat astrocytes: the role of ATP-induced phosphatidyl-inositol breakdown.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Prostaglandin D2; Prostaglandins; Rats; Receptors, Purinergic; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Base Sequence; Calcium; Cattle; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Ionomycin; Molecular Sequence Data; Protein Kinase C; Pyridines; Staurosporine; Stimulation, Chemical; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Zona Glomerulosa | 1992 |
The role of calcium and protein kinase C in the IgE-dependent activation of phosphatidylcholine-specific phospholipase D in a rat mast (RBL 2H3) cell line.
Topics: Alkaloids; Animals; Calcium; Cell Line; Enzyme Activation; Histamine Release; Immunoglobulin E; Indoles; Ionomycin; Kinetics; Maleimides; Mast Cells; Phospholipase D; Protein Kinase C; Rats; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Gonadotropin-releasing hormone-induced calcium signaling in clonal pituitary gonadotrophs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Dihydropyridines; Endoplasmic Reticulum; Gonadotropin-Releasing Hormone; Ionomycin; Nifedipine; Pituitary Gland; Potassium; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Endothelin increases [Ca2+]i in rat pancreatic acinar cells by intracellular release but fails to increase amylase secretion.
Topics: Amylases; Animals; Binding, Competitive; Calcium; Cholecystokinin; Endothelins; In Vitro Techniques; Inositol Phosphates; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Endothelin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Thapsigargin defines the roles of cellular calcium in secretagogue-stimulated enzyme secretion from pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Carbachol; Cytoplasm; Fura-2; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Secretin; Sincalide; Spectrometry, Fluorescence; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoactive Intestinal Peptide | 1992 |
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms | 1992 |
Bombesin stimulates the rapid activation of phospholipase A2-catalyzed phosphatidylcholine hydrolysis in Swiss 3T3 cells.
Topics: 3T3 Cells; Alkaloids; Animals; Arachidonic Acid; Bombesin; Calcium; Calcium-Transporting ATPases; Carbon Radioisotopes; Dose-Response Relationship, Drug; Enzyme Activation; Hydrolysis; Kinetics; Lysophosphatidylcholines; Mice; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
The regulation of phospholipase D activity and its role in sn-1,2-diradylglycerol formation in bombesin- and phorbol 12-myristate 13-acetate-stimulated Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Butanols; Diglycerides; Inositol Phosphates; Mice; Phosphatidylcholines; Phospholipase D; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Amplification of prostaglandin I2 production by thapsigargin.
Topics: Animals; Binding Sites; Cell Line; Epidermal Growth Factor; Epoprostenol; Fibroblast Growth Factor 2; Heparin; Interleukin-1; Liver; Lyngbya Toxins; Rats; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 1991 |
Effect of angiotensin II on cytosolic free calcium in neonatal rat cardiomyocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Binding, Competitive; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cytophotometry; Cytosol; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Angiotensin II inhibits K(+)-induced Ca2+ signal generation in rat adrenal glomerulosa cells.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Calcium Channels; Cyclic AMP; Cytoplasm; Male; Potassium; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Zona Glomerulosa | 1991 |
Thapsigargin potentiates histamine-stimulated HCl secretion in gastric parietal cells but does not mimic cholinergic responses.
Topics: Aminopyrine; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Rabbits; Receptors, Cholinergic; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Stimulatory effect of thapsigargin, a non-TPA-type tumor promoter, on arachidonic acid metabolism in the murine keratinocyte line HEL30 and on epidermal cell proliferation in vivo as compared to the effects of phorbol ester TPA.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; Cell Line; Female; Hyperplasia; Keratinocytes; Mice; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Two tumor promoters, 12-O-tetradecanoylphorbol-13-acetate and thapsigargin, act synergistically via distinct signaling pathways to stimulate gene expression.
Topics: Animals; Base Sequence; Calcium; Carcinogens; Cell Line; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Drug Interactions; Endothelins; Gene Expression Regulation; Matrix Metalloproteinase 3; Metalloendopeptidases; Protein Kinase C; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Transfection | 1990 |
Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Drug; Enzyme Induction; Female; Histamine Release; Histidine Decarboxylase; Irritants; Lactones; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Plant Extracts; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 1986 |
Synergism between thapsigargin and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate on the release of [14C]arachidonic acid and histamine from rat peritoneal mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Carbon Radioisotopes; Drug Synergism; Histamine Release; In Vitro Techniques; Male; Mast Cells; Plant Extracts; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1987 |
Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin.
Topics: Benzofurans; Calcimycin; Calcium; Computer Simulation; Erythrocytes; Fluorescent Dyes; Fura-2; Homeostasis; Humans; Manganese; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1989 |
Diversity in the chemical nature and mechanism of response to tumor promoters.
Topics: Acrylamides; Alkaloids; Animals; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Cnidarian Venoms; Enzyme Induction; Ethers, Cyclic; Mice; Okadaic Acid; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoconstrictor Agents | 1989 |
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion].
Topics: Acrylamides; Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cnidarian Venoms; Enzyme Activation; Humans; Lyngbya Toxins; Mice; Neoplasms, Experimental; Phorbols; Plant Extracts; Protein Kinase C; Receptors, Cell Surface; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thapsigargin | 1986 |
Stimulation of superoxide anion formation by the non-TPA type tumor promoters palytoxin and thapsigargin in porcine and human neutrophils.
Topics: Acrylamides; Animals; Carcinogens; Cnidarian Venoms; Humans; In Vitro Techniques; Lyngbya Toxins; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygen Consumption; Plant Extracts; Superoxides; Swine; Tetradecanoylphorbol Acetate; Thapsigargin | 1987 |
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations.
Topics: Blood Platelets; Calcimycin; Calcium; Cytoplasm; Diltiazem; Humans; Kinetics; Molecular Weight; Nimodipine; Phosphoproteins; Plant Extracts; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Verapamil | 1987 |
Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Macrophages; Peritoneal Cavity; Plant Extracts; Prostaglandins E; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thapsigargin | 1987 |
Inhibition by gossypol of tumor promoter-induced arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Gossypol; Macrophages; Male; Peritoneal Cavity; Plant Extracts; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Cytoplasm; In Vitro Techniques; Isoquinolines; Lyngbya Toxins; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Piperazines; Plant Extracts; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS.
Topics: Acquired Immunodeficiency Syndrome; Benzofurans; Calcimycin; Calcium; Cell Division; Cytoplasm; Drug Interactions; Fluorescent Dyes; Fura-2; Humans; Interleukin-2; Lymphocytes; Phytohemagglutinins; Plant Extracts; Receptors, Interleukin-2; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Cholecystokinin-stimulated enzyme secretion from dispersed rabbit pancreatic acinar cells: phosphorylation-dependent changes in potency and efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amylases; Animals; Calcium-Transporting ATPases; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Pancreas; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sincalide; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1995 |
Influence of calcium on arachidonic acid mobilization by murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages, Peritoneal; Male; Mice; Phospholipases A; Phospholipases A2; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Beta 1 integrin-mediated T cell adhesion is regulated by calcium ionophores and endoplasmic reticulum Ca(2+)-ATPase inhibitors.
Topics: Antibodies, Monoclonal; Antioxidants; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion; Cells, Cultured; Collagen; Endoplasmic Reticulum; Fibronectins; Humans; Hydroquinones; Indoles; Integrin beta1; Integrins; Ionomycin; Laminin; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Carbachol-induced potassium release in rat parotid acini: comparison of the roles of cytosolic Ca2+ and protein kinase C.
Topics: Alkaloids; Amylases; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cytosol; Egtazic Acid; Enzyme Activation; Gallic Acid; Ionomycin; Male; Parotid Gland; Potassium; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Thapsigargin activates lymphocytes via a different pathway from ionomycin.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Ionomycin; Kinetics; Lymphocyte Activation; Lymphocytes; Protein Kinase C; Protein Kinases; Signal Transduction; Swine; Tacrolimus; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Calcium mobilisation controls tyrosine protein phosphorylation independently of the activation of protein kinase C in human platelets.
Topics: Blood Platelets; Calcium; Edetic Acid; Enzyme Activation; Humans; Indoles; Maleimides; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Aggregation; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tyrosine | 1994 |
Effect of signal transduction pathways on the action of thapsigargin on rat mast cells. Crosstalks between cellular signalling and cytosolic pH.
Topics: Animals; Calcium; Cholera Toxin; Cytosol; Histamine Release; Hydrogen-Ion Concentration; Mast Cells; Rats; Rats, Sprague-Dawley; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Differences in intracellular calcium signaling after activation of the thrombin receptor by thrombin and agonist peptide in osteoblast-like cells.
Topics: Amino Acid Sequence; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Molecular Sequence Data; Osteoblasts; Peptides; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Receptors, Thrombin; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tumor Cells, Cultured; Tyrosine | 1994 |
Thrombin-induced increase of F-actin in human umbilical vein endothelial cells.
Topics: Actins; Alkaloids; Calcium; Capillary Permeability; Cells, Cultured; Cytoskeleton; Diterpenes; Endothelium, Vascular; Humans; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 1994 |
Calyculin A, okadaic acid and W-7 interfere with a distal step in pancreatic acinar signal transduction.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcium; Cyclic AMP; Ethers, Cyclic; Inositol 1,4,5-Trisphosphate; Male; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Rats; Rats, Wistar; Secretory Rate; Signal Transduction; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoactive Intestinal Peptide | 1994 |
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells.
Topics: Bucladesine; Cadmium; Calcium; Cations; Fluorescent Dyes; Fura-2; Gadolinium; Humans; Imidazoles; Ion Channels; Manganese; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Oxocins; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1994 |
Inhibition of muscarinic receptor-induced inositol phospholipid hydrolysis by caffeine, beta-adrenoceptors and protein kinase C in intestinal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Caffeine; Calcium Channels; Calcium-Transporting ATPases; Carbachol; Cyclic AMP; Diglycerides; Gallopamil; Guinea Pigs; Hydrolysis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Intestine, Small; Isoproterenol; Muscle, Smooth; Protein Kinase C; Receptors, Adrenergic, beta; Receptors, Muscarinic; Ryanodine; Stereoisomerism; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Control of inositol phosphate turnover in human airways during histamine stimulation.
Topics: Alkaloids; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Histamine; Histamine Release; Humans; Inositol Phosphates; Muscle, Smooth; Protein Kinase C; Respiratory System; Staurosporine; Stimulation, Chemical; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Effects of an aminosteroid inhibitor of phospholipase C-dependent processes on the TCR-mediated signal transduction pathway in human T cells.
Topics: Adjuvants, Immunologic; Calcium; Calcium-Transporting ATPases; CD3 Complex; Enzyme Inhibitors; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Ionomycin; Ionophores; Lymphocyte Activation; Protein Kinase C; Pyrrolidinones; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 1995 |
Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cytosol; Digitonin; Intracellular Membranes; Liver; Male; Mitochondria, Liver; Mitochondrial Swelling; Models, Biological; Permeability; Rats; Rats, Sprague-Dawley; Rotenone; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1995 |
Arachidonic acid increases cytosolic calcium and stimulates hormone release in rat lactotrophs.
Topics: Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Line; Cells, Cultured; Cobalt; Cytosol; Dose-Response Relationship, Drug; Female; Kinetics; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Rats, Wistar; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thyrotropin-Releasing Hormone; Time Factors; Tumor Cells, Cultured | 1995 |
Changes in Ca2+ concentration in phorbol ester and thapsigargin treated glioma C6 cells. The role of protein kinase C in regulation of Ca2+ entry.
Topics: Animals; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytoskeleton; Endoplasmic Reticulum; Glioma; Mice; Neoplasm Proteins; Nerve Tissue Proteins; Protein Kinase C; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Calcimycin; Calcium; Calcium-Transporting ATPases; Cholera Toxin; Colforsin; Drug Synergism; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Hydroquinones; Isoquinolines; Leukemia-Lymphoma, Adult T-Cell; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Involvement of protein kinase C in agonist-stimulated goldfish ovulation.
Topics: Alkaloids; Animals; Calcimycin; Dinoprost; Female; Goldfish; Hydrogen-Ion Concentration; In Vitro Techniques; Naphthalenes; Ovulation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vanadates | 1993 |
Sodium fluoride stimulates exocytosis at a late site of calcium interaction in stimulus-secretion coupling: studies with the RINm5F beta cell line.
Topics: Aluminum; Animals; Arachidonic Acid; Calcium; Calcium-Binding Proteins; Cell Line; Colforsin; Cyclic AMP; Deferoxamine; Exocytosis; Extracellular Space; Insulin; Insulin Secretion; Ionomycin; Islets of Langerhans; Kinetics; Melitten; Nitrendipine; Potassium Chloride; Protein Kinase C; Secretory Rate; Sodium Fluoride; Stimulation, Chemical; Sulfonamides; Temperature; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1995 |
Unusual carbachol responses in RINm5F cells: evidence for a "distal" site of action in stimulus-secretion coupling.
Topics: Arachidonic Acid; Calcium; Carbachol; Cells, Cultured; Guanosine Triphosphate; Insulin; Insulin Secretion; Membrane Potentials; Protein Kinase C; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis.
Topics: Administration, Topical; Animals; Anthracenes; Base Sequence; Blotting, Northern; Carcinogens; DNA Primers; Ethers, Cyclic; Female; Fluorescent Antibody Technique; Gene Expression; Mice; Mice, Inbred SENCAR; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; RNA, Messenger; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha | 1995 |
Synergistic interaction of Y1-neuropeptide Y and alpha 1b-adrenergic receptors in the regulation of phospholipase C, protein kinase C, and arachidonic acid production.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Arachidonic Acid; Calcium; CHO Cells; Cricetinae; Drug Synergism; Enzyme Activation; Hydroquinones; Inositol 1,4,5-Trisphosphate; Peptide YY; Peptides; Pertussis Toxin; Phenylephrine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Protein Kinase C; Receptors, Adrenergic, alpha-1; Receptors, Neuropeptide Y; Recombinant Fusion Proteins; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 1995 |
[Secretion of peptide YY and truncated glucagon-like peptide 1 by isolated intestinal cells in rats].
Topics: Adult; Animals; Calcium-Transporting ATPases; Chromatography, Affinity; Glucagon; Glucagon-Like Peptide 1; Humans; Intestinal Mucosa; Ionomycin; Male; Peptide Fragments; Peptide YY; Peptides; Phorbols; Protein Precursors; Rats; Rats, Wistar; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Thapsigargin inhibits Ca2+ entry into human neutrophil granulocytes.
Topics: Biological Transport; Calcium; Dose-Response Relationship, Drug; Humans; Neutrophils; Phosphorylation; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
The absence of extracellular calcium potentiates the killing of cultured hepatocytes by aluminum maltolate.
Topics: Aluminum; Animals; Calcium; Cell Death; Cell Membrane Permeability; Cyclic AMP; Deferoxamine; Dose-Response Relationship, Drug; Liver; Male; Mitochondria; Organometallic Compounds; Oxidative Stress; Protein Kinases; Pyrones; Rats; Rats, Sprague-Dawley; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Time Factors | 1995 |
Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils.
Topics: Alkaloids; Animals; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Cytosol; Electrophysiology; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Spectrometry, Fluorescence; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Calcium-mobilizing agonists stimulate anion fluxes in cultured endothelial cells from human umbilical vein.
Topics: Anions; Calcium; Cells, Cultured; Chloride Channels; Egtazic Acid; Endothelium, Vascular; Histamine; Humans; Iodine; Ionomycin; Protein Kinase C; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 1994 |
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Mechanism of activation of the Na+/H+ exchanger by arginine vasopressin in hepatocytes.
Topics: Animals; Arginine Vasopressin; Calcium; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Male; Osmolar Concentration; Protein Kinase C; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Protein kinase C mediates the calcium-induced activation of rat colonic particulate guanylate cyclase.
Topics: Alkaloids; Animals; Calcium; Colon; Enzyme Activation; Estrenes; Guanylate Cyclase; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Regulation of T-cell-receptor-stimulated bivalent-cation entry in Jurkat E6 cells: role of protein kinase C.
Topics: Alkaloids; Antibodies, Monoclonal; Antigen-Antibody Complex; Calcium; CD3 Complex; Cell Line; Enzyme Activation; Fura-2; Indoles; Maleimides; Manganese; Protein Kinase C; Receptors, Antigen, T-Cell; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Modulatory effect of 4 beta-phorbol 12-myristate 13-acetate (PMA) on carbachol-induced Ca2+ mobilization in rat parotid acinar cells.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Enzyme Activation; Inositol Phosphates; Ionomycin; Male; Parotid Gland; Rats; Rats, Wistar; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Ca2+ efflux from platelets. Control by protein kinase C and the filling state of the intracellular Ca2+ stores.
Topics: Alkaloids; Blood Platelets; Calcium; Calcium Radioisotopes; Calcium-Transporting ATPases; Cytoplasmic Granules; Cytosol; Dose-Response Relationship, Drug; Egtazic Acid; Exocytosis; Fluorescent Dyes; Humans; In Vitro Techniques; Indoles; Ionomycin; Kinetics; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin | 1994 |
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Bradykinin; Calcium; Calcium-Transporting ATPases; Cytosol; DNA; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Lysophospholipids; Mice; Phorbol Esters; Second Messenger Systems; Sphingosine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
Phenylarsine oxide and phorbol myristate acetate inhibit the CD3-induced rise of cytosolic Ca2+ in Jurkat cells by refilling internal Ca2+ stores.
Topics: Arsenicals; Biological Transport; Calcium; CD3 Complex; Cell Line; Cytosol; Ethers, Cyclic; Humans; Ionomycin; Okadaic Acid; Phosphatidylserines; Phosphorylation; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1994 |
Protein kinase C activates capacitative calcium entry in the insulin secreting cell line RINm5F.
Topics: Alkaloids; Animals; Biological Transport; Calcium; Cytosol; Insulin; Insulin Secretion; Insulinoma; Manganese; Pancreatic Neoplasms; Protein Kinase C; Rats; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1994 |
Potentiation of glucocorticoid-mediated induction of the mouse mammary tumor virus promoter in mammary carcinoma cells by activation of protein kinase C.
Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Lactams; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Phorbol Esters; Promoter Regions, Genetic; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1994 |
Regulation of membrane potential by G-protein-coupled receptors in L6 skeletal myocytes: the role of second messengers.
Topics: Animals; Calcium-Transporting ATPases; Carbachol; Cell Line; GTP-Binding Proteins; Membrane Potentials; Muscles; Receptors, Cell Surface; Second Messenger Systems; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1993 |
Protein kinase C and calcium distribution in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; Hypertension; Isoquinolines; Muscle, Smooth, Vascular; Piperazines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Calcium is involved in both positive and negative modulation of the secretory system for ANP.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Egtazic Acid; Endothelins; Fibroblast Growth Factors; Gallic Acid; Heart; Heart Atria; Kinetics; Models, Cardiovascular; Myocardium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Ryanodine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
Ability of the non-phorbol ester-type tumor-promoter thapsigargin to mimic the stimulatory effects of 12-0-tetradecanoylphorbol-13-acetate on ornithine decarboxylase activity, hydroperoxide production, and macromolecule synthesis in mouse epidermis in viv
Topics: Animals; Carcinogens; DNA; Dose-Response Relationship, Drug; Enzyme Induction; Female; Hydrogen Peroxide; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Xanthine Oxidase | 1993 |
The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements.
Topics: Biological Transport; Calcium; Cell Line; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; N-Formylmethionine Leucyl-Phenylalanine; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides | 1993 |
[Effect of epidermal growth factor (EGF) on mouse sperm capacitation].
Topics: Animals; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Mice; Mice, Inbred Strains; Phosphorylation; Protein-Tyrosine Kinases; Sperm Capacitation; Stimulation, Chemical; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
The role of cytosolic Ca2+, protein kinase C, and protein kinase A in hormonal stimulation of phospholipase D in rat hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ethers, Cyclic; Glycerophospholipids; Isoquinolines; Liver; Male; Okadaic Acid; Phosphatidic Acids; Phospholipase D; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1994 |
ATP-induced entry of calcium in thyroid FRTL-5 cells. Studies with phorbol myristate acetate and thapsigargin.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Calcium; Cell Line; Enzyme Activation; Imidazoles; Ionomycin; Protein Kinase C; Rats; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland | 1993 |
Hormonal stimulation of Mg2+ uptake in hepatocytes. Regulation by plasma membrane and intracellular organelles.
Topics: Animals; Biological Transport; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Chlorides; Egtazic Acid; Hormones; Liver; Magnesium; Male; Norepinephrine; Organelles; Rats; Rats, Sprague-Dawley; Sodium; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Intracellular free sodium concentrations in GH4C1 cells.
Topics: Animals; Benzofurans; Calcium; Calcium Channels; Cell Line; Clone Cells; Ethers, Cyclic; Fluorescent Dyes; Membrane Potentials; Monensin; Ouabain; Pituitary Gland; Rats; Sodium; Sodium Channels; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thyrotropin-Releasing Hormone | 1993 |
Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; Hydrolysis; Isoproterenol; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1993 |
Induction of superoxide by 12-O-tetradecanoylphorbol-13-acetate and thapsigargin, a non-phorbol-ester-type tumor promoter, in peritoneal macrophages elicited from SENCAR and B6C3F1 mice: a permissive role for the arachidonic acid cascade in signal transdu
Topics: Analysis of Variance; Animals; Arachidonic Acid; Carcinogens; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Female; Macrophages; Mice; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Species Specificity; Specific Pathogen-Free Organisms; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Efflux of cyclic GMP from activated human platelets.
Topics: Blood Platelets; Calcium; Cyclic GMP; Humans; In Vitro Techniques; Nitroprusside; Platelet Activation; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin | 1993 |
Role of intracellular calcium and protein kinases in the activation of hepatic Na+/taurocholate cotransport by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Colforsin; Cyclic AMP; Ionomycin; Kinetics; Liver; Phenylephrine; Protein Kinase Inhibitors; Protein Kinases; Rats; Sodium; Taurocholic Acid; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1993 |
Characterization of a unique enhancer element responsive to cyclic adenosine 3',5'-monophosphate and elevated calcium.
Topics: Base Sequence; Binding, Competitive; Calcium; Cell Line; Cell Nucleus; Cyclic AMP; DNA; Drug Interactions; Enhancer Elements, Genetic; Epidermal Growth Factor; Fibroblasts; Gene Expression; Molecular Sequence Data; Nuclear Proteins; Repetitive Sequences, Nucleic Acid; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Modulatory effect of protein kinase C on thapsigargin-induced calcium entry in thyroid FRTL-5 cells.
Topics: Biological Transport; Calcium; Cells, Cultured; Enzyme Activation; Membrane Potentials; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland | 1993 |
A role for protein phosphorylation in modulating Ca2+ elevation in rabbit platelets treated with thapsigargin.
Topics: Animals; Blood Platelets; Blood Proteins; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cyclooxygenase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Heparin; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Manganese; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rabbits; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine | 1996 |
Enteric glia exhibit P2U receptors that increase cytosolic calcium by a phospholipase C-dependent mechanism.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Culture Techniques; Cytosol; Extracellular Space; Guinea Pigs; Immunohistochemistry; Male; Myenteric Plexus; Neuroglia; Osmolar Concentration; Pertussis Toxin; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Thapsigargin, a weak skin tumor promoter, alters the growth and differentiation of mouse keratinocytes in culture.
Topics: Animals; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cells, Cultured; Drug Synergism; Female; Hyperplasia; Keratinocytes; Mice; Phenotype; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Differential effects of the protein kinase C activator phorbol 12-myristate 13-acetate on calcium responses and secretion in adherent and suspended RBL-2H3 mucosal mast cells.
Topics: Animals; Antigens; Biological Transport; Calcium; Cell Adhesion; Enzyme Activation; Isoenzymes; Mast Cells; Phosphorylation; Protein Kinase C; Rats; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured; Tyrosine | 1996 |
Differential effects of phorbol ester on apoptosis in HL-60 promyelocytic leukemia cells.
Topics: Apoptosis; Calcimycin; Calcium; Down-Regulation; Enzyme Inhibitors; HL-60 Cells; Homeostasis; Humans; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Thapsigargin modulates agonist-stimulated cyclic AMP responses through cytosolic calcium-dependent and -independent mechanisms in rat pinealocytes.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cyclic AMP; Enzyme Inhibitors; Indoles; Isoproterenol; Male; Norepinephrine; Pineal Gland; Protein Kinase C; Rats; Rats, Sprague-Dawley; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Line; Chelating Agents; Dogs; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Immunoglobulin A; Inositol 1,4,5-Trisphosphate; Microtubules; Models, Biological; Protein Kinase C; Receptors, Polymeric Immunoglobulin; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) elevates basal B-cell intracellular calcium concentration and suppresses surface Ig- but not CD40-induced antibody secretion.
Topics: Animals; Antibodies; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcium; CD40 Antigens; Cells, Cultured; Enzyme Inhibitors; Female; Intracellular Fluid; Ionomycin; Ionophores; Lipopolysaccharides; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Receptors, Antigen, B-Cell; Solubility; T-Lymphocytes, Helper-Inducer; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils.
Topics: Adrenal Glands; Alkaloids; Animals; Azepines; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Ion Transport; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Triazoles | 1996 |
Tyrosine kinase is involved in angiotensin II-stimulated phospholipase D activation in aortic smooth muscle cells: function of Ca2+ influx.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Genistein; Inositol Phosphates; Ionophores; Isoflavones; Membrane Lipids; Muscle Proteins; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production.
Topics: Carcinogens; Dose-Response Relationship, Drug; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lyngbya Toxins; Molecular Structure; Okadaic Acid; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Thalidomide; Thapsigargin; Tumor Necrosis Factor-alpha | 1996 |
Differential effects of protein kinase C activation on calcium storage and capacitative calcium entry in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Calcium; Enzyme Activation; Enzyme Inhibitors; Homeostasis; Indoles; Ion Transport; Mice; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Down-regulation of the protein kinase A pathway by activators of protein kinase C and intracellular Ca2+ in fibroblast cells.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium-Transporting ATPases; Chloramphenicol O-Acetyltransferase; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, fos; Genes, jun; Mice; Phosphoprotein Phosphatases; Protein Kinase C; Recombinant Proteins; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factor AP-1; Transcription, Genetic; Transfection | 1996 |
Correlation between increased AP-1NGF binding activity and induction of nerve growth factor transcription by multiple signal transduction pathways in C6-2B glioma cells.
Topics: Animals; Base Sequence; Cell Line; Cell Nucleus; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glioma; Isoproterenol; Molecular Sequence Data; Nerve Growth Factors; Oligodeoxyribonucleotides; Rats; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Pharmacological studies on mechanisms involved in Ca2+ oscillations in rat megakaryocytes.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Female; Indoles; Male; Megakaryocytes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Synergistic cooperation between thapsigargin and phorbol ester for induction of nitric oxide synthesis in murine peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Chelating Agents; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Humans; Hydroquinones; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1996 |
Protein kinase C modulates cytosolic free calcium by stimulating calcium pump activity in Jurkat T cells.
Topics: Alkaloids; Calcium; Calcium-Transporting ATPases; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Ionophores; Lanthanum; Leukemia; Naphthalenes; Phorbol Esters; Protein Kinase C; Sodium; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1995 |
Activation of NF-kappa B by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers.
Topics: Antioxidants; Calcium; Calcium-Transporting ATPases; Chelating Agents; Deoxyglucose; Endoplasmic Reticulum; HeLa Cells; Humans; Indoles; NF-kappa B; Protein Kinase C; Pyrazoles; Reactive Oxygen Species; Stress, Physiological; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Necrosis Factor-alpha | 1996 |
Upregulation of Na(+)-dependent alanine transport in vascular endothelial cells by serum: role of intracellular Ca2+.
Topics: Alanine; Amino Acid Transport Systems; Animals; Biological Transport, Active; Blood; Calcium; Carrier Proteins; Cattle; Cells, Cultured; Cycloheximide; Egtazic Acid; Endothelium, Vascular; Ouabain; Pertussis Toxin; Potassium; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Up-Regulation; Virulence Factors, Bordetella | 1994 |
Propofol regulation of calcium entry pathways in cultured A10 and rat aortic smooth muscle cells.
Topics: Anesthetics, Intravenous; Animals; Aorta; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Inositol Phosphates; Muscle, Smooth, Vascular; Nicardipine; Propofol; Rats; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: effects on mitochondrial function.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antibodies, Blocking; Apoptosis; Calcium; Calcium-Transporting ATPases; Carcinogens; CD3 Complex; Cell Count; Cell Membrane; Cyclosporine; Flow Cytometry; Intracellular Membranes; Membrane Potentials; Mice; Mitochondrial Swelling; Phosphorylation; Tetradecanoylphorbol Acetate; Thapsigargin; Thymus Gland | 1996 |
Effects of staurosporine on the capacitative regulation of the state of the Ca2+ reserves in activated Jurkat T lymphocytes.
Topics: Antibodies, Monoclonal; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Chelating Agents; Computer Simulation; Econazole; Egtazic Acid; Enzyme Inhibitors; Fura-2; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Models, Immunological; Nickel; Protein Kinase C; Receptors, Antigen, T-Cell, alpha-beta; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Pituitary adenylate cyclase-activating peptide, carbachol, and glucose stimulate insulin release in the absence of an increase in intracellular Ca2+.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Cells, Cultured; Colforsin; Glucose; Insulin; Insulin Secretion; Intracellular Fluid; Islets of Langerhans; Neuropeptides; Nitrendipine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Inhibition by fenamates of calcium influx and proliferation of human lymphocytes.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cell Division; Concanavalin A; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flufenamic Acid; Humans; Imidazoles; Lymphocytes; Manganese; ortho-Aminobenzoates; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Evidence for a phorbol ester-insensitive phosphorylation step in capacitative calcium entry in rat thymic lymphocytes.
Topics: Animals; Biological Transport; Calcium; Enzyme Inhibitors; Ion Transport; Lymphocytes; Male; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thapsigargin; Thymus Gland | 1996 |
Na(+)-K(+)-Cl- cotransport system in brain capillary endothelial cells: response to endothelin and hypoxia.
Topics: Animals; Brain; Carrier Proteins; Cells, Cultured; Chlorides; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia, Brain; Indoles; Maleimides; Membrane Proteins; Potassium; Rats; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Regulation of taurine transport in rat astrocytes by protein kinase C: role of calcium and calmodulin.
Topics: Animals; Astrocytes; Binding, Competitive; Biological Transport; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Diglycerides; Enzyme Activation; Kinetics; Protein Kinase C; Rats; Taurine; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Induction of cytosolic Ca2+ elevation mediated by Mas-7 occurs through membrane pore formation.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Cattle; Cell Membrane; Cell Membrane Permeability; Cytosol; Enzyme Inhibitors; Extracellular Space; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Intercellular Signaling Peptides and Proteins; Ion Channels; Lipid Bilayers; Manganese; Membrane Potentials; Peptides; Phosphatidylinositols; Protein Kinase C; Signal Transduction; Sodium; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured; Wasp Venoms | 1996 |
Distinct mechanisms of neurotransmitter release from PC 12 cells exposed to lead.
Topics: Animals; Cadmium; Calcium Channels; Calcium-Transporting ATPases; Carcinogens; Chromogranins; Enzyme Inhibitors; Lead; Ligands; Microsomes; Neuropeptides; Nickel; Norepinephrine; PC12 Cells; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 1996 |
Effects of three different Ca(2+)-ATPase inhibitors on Ca2+ response and leukotriene release in RBL-2H3 cells.
Topics: Animals; Basophils; Calcium; Calcium-Transporting ATPases; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroquinones; Indoles; Leukemia, Basophilic, Acute; Leukotriene C4; Lipoxygenase Inhibitors; Mice; Naphthalenes; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1996 |
Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; Carcinogens; Cell Division; Cytosol; Enzyme Inhibitors; Female; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Interleukin-2; Intracellular Fluid; Ionophores; Lectins, C-Type; Lupus Erythematosus, Systemic; Lymphocyte Activation; Protein Kinase C; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Activation-secretion coupling in 10P2 murine mast cells challenged with IgE-antigen, ionophore A23187, thapsigargin and phorbol ester.
Topics: 2,4-Dinitrophenol; Analysis of Variance; Animals; Antigens; Calcimycin; Carcinogens; Cell Line; Immunization, Passive; Immunoglobulin E; Interleukin-4; Ionophores; Mast Cells; Mice; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Antigen activation of mitogen-activated protein kinase in mast cells through protein kinase C-dependent and independent pathways.
Topics: Animals; Antigens; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Cycle Proteins; Cells, Cultured; Enzyme Activation; Enzyme Precursors; GTP-Binding Proteins; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Mast Cells; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Rats; Syk Kinase; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Characterization of the hypo-osmolarity-induced Ca2+ response in cultured rat astrocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Bradykinin; Brain; Calcium; Cells, Cultured; Chelating Agents; Culture Media; Egtazic Acid; Flunarizine; Hypotonic Solutions; Kinetics; Nimodipine; Rats; Rats, Wistar; Ryanodine; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages.
Topics: Animals; Antirheumatic Agents; Arachidonic Acid; Auranofin; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; In Vitro Techniques; Ionophores; Isoenzymes; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Depletion of glutathione by benzo(a)pyrene metabolites, ionomycin, thapsigargin, and phorbol myristate in human peripheral blood mononuclear cells.
Topics: Benzo(a)pyrene; Benzoflavones; Calcium; Enzyme Activation; Glutathione; Humans; Ionomycin; Lymphocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver; Mitogen-Activated Protein Kinases; Models, Biological; Polyenes; Protein Kinases; Rats; Recombinant Proteins; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 1997 |
Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism.
Topics: Arachidonic Acid; Astrocytoma; Brain Neoplasms; Calcimycin; Calcium; Carbachol; Carcinogens; Cytosol; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ionophores; Phospholipases A; Phospholipases A2; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1997 |
A new concept for risk assessment of the hazards of non-genotoxic chemicals--electronmicroscopic studies of the cell surface. Evidence for the action of lipophilic chemicals on the Ca2+ signaling system.
Topics: Alkanes; Animals; Calcium; Carbon Disulfide; Carcinogens; Cell Division; Cells, Cultured; Cholinesterase Inhibitors; Dimethyl Sulfoxide; Dimethylformamide; Ethanol; Hexanones; Liver; Microscopy, Electron, Scanning; Microvilli; Rats; Receptors, Vasopressin; Risk Assessment; Signal Transduction; Solvents; Styrene; Styrenes; Tetradecanoylphorbol Acetate; Thapsigargin; Toluene | 1997 |
Ca2+ and protein kinase C-dependent mechanisms involved in gastrin-induced Shc/Grb2 complex formation and P44-mitogen-activated protein kinase activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Gastrins; GRB2 Adaptor Protein; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms, Experimental; Phosphorylation; Protein Kinase C; Proteins; Rats; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured; Tyrosine | 1997 |
Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers.
Topics: Ammonia; Barium; Calcimycin; Calcium; Carbachol; Cell Line; Chlorides; Colforsin; Cyclic AMP; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Intestinal Mucosa; Intracellular Membranes; Ionomycin; Ionophores; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Activation of MAP kinases, cPLA2 and reactive oxygen species formation by EGF and calcium mobilizing agonists in a human keratinocyte cell line.
Topics: Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Ionophores; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Phorbol ester and calcium regulation of corticotrophin-releasing factor receptor 1 expression in a neuronal cell line.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Carbachol; Cell Line; Corticotropin-Releasing Hormone; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Kinetics; Mice; Nifedipine; Phenanthridines; Protein Kinase C; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic | 1997 |
Intracellular calcium concentration and hormone secretion are controlled differently by TRH in rat neonatal lactotrophs and somatotrophs.
Topics: Animals; Animals, Newborn; Cadmium Chloride; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cells, Cultured; Female; Growth Hormone; Immunohistochemistry; Intracellular Fluid; Membrane Potentials; Patch-Clamp Techniques; Pituitary Gland; Prolactin; Protein Kinase C; Radioimmunoassay; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thapsigargin; Thyrotropin-Releasing Hormone | 1997 |
Effects of dexamethasone and phorbol ester on P2 receptor-coupled Ca2+ signalling and lipocortin 1 presentation in U937 cells.
Topics: Adenosine Triphosphate; Annexin A1; Calcium; Cell Line; Cell Membrane; Dexamethasone; Ion Transport; Receptors, Purinergic P2; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton.
Topics: Actin Cytoskeleton; Actins; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcimycin; Calcium; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; GTP-Binding Proteins; Indoles; Maleimides; Mice; Neurokinin B; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Bombesin; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 1997 |
Serine base exchange enzyme activity is modulated by sphingosine and other amphiphilic compounds: possible role of positive charge in increasing the synthesis of phosphatidylserine.
Topics: Animals; Cholesterol Esters; Glioma; Kinetics; Microsomes; Microsomes, Liver; Nitrogenous Group Transferases; Phosphatidylserines; Phosphorylcholine; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1997 |
Differential routes of Ca2+ influx in Swiss 3T3 fibroblasts in response to receptor stimulation.
Topics: 3T3 Cells; Alprostadil; Angiotensin II; Animals; Arachidonic Acid; Bombesin; Bradykinin; Calcium; Calcium Channel Blockers; Diltiazem; Endothelins; Enzyme Activation; GTP-Binding Proteins; Inositol Phosphates; Mice; Nifedipine; Pertussis Toxin; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Vasopressins; Virulence Factors, Bordetella | 1998 |
Farnesol inhibits L-type Ca2+ channels in vascular smooth muscle cells.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Cells, Cultured; Drug Interactions; Farnesol; In Vitro Techniques; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Phosphatidylcholine-specific phospholipase C regulates thapsigargin-induced calcium influx in human lymphocytes.
Topics: Bridged-Ring Compounds; Butanols; Calcium; Enzyme Inhibitors; Estrenes; Humans; Indoles; Lymphocytes; Nickel; Norbornanes; Phosphatidylcholines; Phosphatidylinositols; Propranolol; Pyrrolidinones; Tetradecanoylphorbol Acetate; Thapsigargin; Thiocarbamates; Thiones; Type C Phospholipases | 1997 |
Bcl-2 inhibits c-fos induction by calcium.
Topics: Animals; Calcium; Cytosol; Extracellular Space; Gene Expression Regulation, Neoplastic; Genes, fos; Lymphoma; Mice; Mice, Inbred BALB C; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Cells, Cultured | 1997 |
Store-operated Ca2+ entry in insulin-releasing pancreatic beta-cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cells, Cultured; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Gallopamil; Genistein; Insulin; Islets of Langerhans; Lanthanum; Manganese; Mice; Mice, Obese; Okadaic Acid; Pancreas; Phosphoprotein Phosphatases; Protein-Tyrosine Kinases; Strontium; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1997 |
ATP and UTP activate calcium-mobilizing P2U-like receptors and act synergistically with interleukin-1 to stimulate prostaglandin E2 release from human rheumatoid synovial cells.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Buffers; Calcium; Dinoprostone; Drug Synergism; Humans; Interleukin-1; Middle Aged; Purinergic Agonists; Receptors, Purinergic; Synovial Membrane; Tetradecanoylphorbol Acetate; Thapsigargin; Uridine Triphosphate | 1998 |
Protein tyrosine phosphorylation and calcium signaling in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; Genistein; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Ca2+ signaling modulates cytolytic T lymphocyte effector functions.
Topics: Antigens, CD; Calcium; CD8-Positive T-Lymphocytes; Cell Line; Clone Cells; Cytotoxicity, Immunologic; Exocytosis; Fas Ligand Protein; fas Receptor; Granzymes; Ionomycin; Ionophores; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Serine Endopeptidases; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Mechanisms regulating prostaglandin F2 alpha secretion from the bovine endometrium.
Topics: Animals; Calcimycin; Calcium; Cattle; Dinoprost; Endometrium; Enzyme Activation; Female; Inositol 1,4,5-Trisphosphate; Oxytocin; Pregnancy; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
A calcium-dependent tyrosine kinase splice variant in human monocytes. Activation by a two-stage process involving adherence and a subsequent intracellular signal.
Topics: Alternative Splicing; Amino Acid Sequence; Calcium; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL5; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Genetic Variation; Humans; Isoenzymes; Jurkat Cells; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
[Role of protein kinase C in the regulation of Ca-responses induced by purinergic agonists and thapsigargin in rat peritoneal macrophages].
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Macrophages, Peritoneal; Protein Kinase C; Purinergic Agonists; Rats; Tetradecanoylphorbol Acetate; Thapsigargin; Uridine Triphosphate | 1998 |
Alterations in calcium metabolism in murine macrophages by the benzene metabolite 1,4-benzoquinone.
Topics: Animals; Benzoquinones; Calcium; Calcium Channels; Calcium-Transporting ATPases; Carcinogens; Catechols; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Hydroquinones; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mutagens; Receptors, Cytoplasmic and Nuclear; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Capacitative Ca2+ entry in enteric glia induced by thapsigargin and extracellular ATP.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Barium; Benzophenanthridines; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Kinetics; Lanthanum; Microsomes; Myenteric Plexus; Neuroglia; Phenanthridines; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Regulation of apical membrane Na+/H+ exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe.
Topics: Amiloride; Cell Line; Cell Membrane; Cyclic AMP; Cyclic GMP; Guanidines; Humans; Intestinal Mucosa; Kinetics; Phenotype; Recombinant Proteins; Second Messenger Systems; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sulfones; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Time Factors; Transfection | 1998 |
Extracellular Ca2+ regulates the respiratory burst of human neutrophils.
Topics: Calcium; Cytosol; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Opposing contributions of NR1 and NR2 to protein kinase C modulation of NMDA receptors.
Topics: Calcium; Cell Line; Enzyme Activation; Humans; Indoles; Kidney; Maleimides; Mutagenesis, Site-Directed; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection | 1998 |
Varying very low-density lipoprotein secretion of rat hepatocytes by altering cellular levels of calcium and the activity of protein kinase C.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cholesterol; Culture Media; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Ketone Bodies; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Phenanthridines; Phenylephrine; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Opposing effects of protein kinase A and C on capacitative calcium entry into HL-60 promyelocytes.
Topics: Calcium; Calcium-Transporting ATPases; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Granulocytes; HL-60 Cells; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
A genome-wide functional assay of signal transduction in living mammalian cells.
Topics: beta-Lactamases; Cell Separation; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Genes, Reporter; Genome; Humans; Jurkat Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Concerted action of cytosolic Ca2+ and protein kinase C in receptor-mediated phospholipase D activation in Chinese hamster ovary cells expressing the cholecystokinin-A receptor.
Topics: Alkaloids; Animals; Benzophenanthridines; Brain; Calcium; CHO Cells; Cricetinae; Cytosol; Down-Regulation; Enzyme Activation; Glycerophospholipids; Phenanthridines; Phospholipase D; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Role of Ca2+-ATPase inhibitors in activation of cytosolic phospholipase A2 in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cell-Free System; Chelating Agents; Cytosol; DNA, Complementary; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lipid Metabolism; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Binding; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; U937 Cells | 1999 |
Sodium, PMA and calcium play an important role on intracellular pH modulation in rat mast cells.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Cyclic AMP; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ion Transport; Mast Cells; Ouabain; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
NF-kappaB or AP-1-dependent reporter gene expression is not altered in human U937 cells exposed to power-line frequency magnetic fields.
Topics: Chloramphenicol O-Acetyltransferase; Electromagnetic Fields; Gene Expression; Genes, Reporter; HIV Long Terminal Repeat; Humans; NF-kappa B; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factor AP-1; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
[Intracellular regulation of neuronal nicotinic cholinergic receptors].
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Nicotinic; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Redox modulation of intracellular free calcium concentration in thyroid FRTL-5 cells: evidence for an enhanced extrusion of calcium.
Topics: Animals; Barium; Calcium; Calcium-Transporting ATPases; Cell Line; Enzyme Activation; Hydrogen-Ion Concentration; Imidazoles; Membrane Potentials; Mercaptoethanol; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Staurosporine; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Thapsigargin; Thimerosal; Thyroid Gland; Vanadates | 1999 |
Intracellular pathways mediating Na+/H+ exchange activation by platelet-derived growth factor in rat hepatic stellate cells.
Topics: Animals; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Division; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Hydrogen-Ion Concentration; Intracellular Fluid; Ion Transport; Liver; Male; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drugs, Chinese Herbal; Enzyme Induction; Isoenzymes; Isoflavones; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Intracellular free calcium regulates the onset of the respiratory burst of human neutrophils activated by phorbol myristate acetate.
Topics: Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intracellular Fluid; Mitogens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Modulatory effect of HCO3- on rat mast cell exocytosis: cross-talks between bicarbonate and calcium.
Topics: Animals; Bicarbonates; Calcimycin; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exocytosis; Histamine Release; Ionophores; Kinetics; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1999 |
Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tumor Necrosis Factor-alpha | 1999 |
Sphingosine and phorbol ester modulate protein kinase C activity and modify ATP-evoked calcium mobilization in glioma C6 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Endoplasmic Reticulum; Enzyme Activation; Glioma; Indoles; Maleimides; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Tumor Cells, Cultured; Type C Phospholipases | 1999 |
Protein kinase C epsilon-dependent pathway of extracellular signal-regulated protein kinase activation by P2Y1 and P2Y2 purinoceptors that activate cytosolic phospholipase A2 in endothelial cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Flavonoids; Indoles; Isoenzymes; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Kinases; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Tritium; Uridine Triphosphate | 1999 |
Protein kinase C activator PMA reduces the Ca(2+) response to antigen stimulation of adherent RBL-2H3 mucosal mast cells by inhibiting depletion of intracellular Ca(2+) stores.
Topics: Antigens; Calcium; Cell Adhesion; Cell Line; Enzyme Activation; Fluorescent Dyes; Fura-2; Logistic Models; Mast Cells; Patch-Clamp Techniques; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Cytosolic Ca2+ oscillations by gastrin releasing peptide in single HIT-T15 cells.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytosol; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Gastrin-Releasing Peptide; Glucose; Ion Channel Gating; Islets of Langerhans; Mice; Nifedipine; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Thapsigargin has similar effect on p53 protein response to benzo[a]pyrene-DNA adducts as TPA in mouse skin.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetone; Animals; Calcium; Carcinogens; Depression, Chemical; DNA Adducts; DNA Damage; Epidermis; Gene Expression Regulation; Genes, p53; Male; Mice; Mice, Inbred C57BL; Microscopy, Immunoelectron; Mitochondria; Organelles; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Suppressor Protein p53 | 1999 |
Bradykinin induces interleukin-6 expression in astrocytes through activation of nuclear factor-kappaB.
Topics: Animals; Animals, Newborn; Astrocytes; Benzylamines; Bradykinin; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Interleukin-6; Kinetics; Luciferases; Maleimides; Mice; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Recombinant Fusion Proteins; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Transfection | 1999 |
Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Calcimycin; Calcium; Cell Adhesion Molecules; Cholecystokinin; Colchicine; Cytochalasin D; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Models, Biological; Pancreas; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 1999 |
Cellular activation by Ca2+ release from stores in the endoplasmic reticulum but not by increased free Ca2+ in the cytosol.
Topics: Animals; Calcium Signaling; Chelating Agents; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Female; In Vitro Techniques; Ionomycin; Ionophores; Lung; Phospholipids; Proteolipids; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions.
Topics: Calcitriol; Calcium; Calcium Channel Agonists; Cell Differentiation; Dimethyl Sulfoxide; Down-Regulation; Enzyme Inhibitors; Gene Products, nef; HL-60 Cells; Humans; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src Homology Domains; src-Family Kinases; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 1999 |
A novel mechanism for the melatonin inhibition of testosterone secretion by rat Leydig cells: reduction of GnRH-induced increase in cytosolic Ca2+.
Topics: 17-alpha-Hydroxyprogesterone; Animals; Arachidonic Acid; Calcium; Calcium Signaling; Cells, Cultured; Drug Synergism; Fura-2; Gonadotropin-Releasing Hormone; Ionomycin; Leydig Cells; Luteinizing Hormone; Male; Melatonin; Pertussis Toxin; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 1999 |
Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol).
Topics: Animals; Blotting, Western; Calcimycin; Carrier Proteins; DNA Fragmentation; DNA, Complementary; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Ionomycin; Ionophores; Mice; Molecular Chaperones; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin; Thymoma; Trichothecenes | 2000 |
Neuropeptide Y (NPY) potentiates phenylephrine-induced mitogen-activated protein kinase activation in primary cardiomyocytes via NPY Y5 receptors.
Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Neuropeptide Y; Pertussis Toxin; Phenylephrine; Phosphorylation; Protein Kinase C; Receptors, Neuropeptide Y; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 2000 |
Cholinergic-induced Ca2+ elevation in rat lacrimal gland acini is negatively modulated by PKCdelta and PKCepsilon.
Topics: Animals; Calcium; Carbachol; Cholinergic Agonists; Enzyme Activation; Enzyme Inhibitors; Fura-2; Isoenzymes; Lacrimal Apparatus; Male; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Induction and secretion of the chemokines interleukin-8 and monocyte chemotactic protein-1 in human immature leukemia cell lines.
Topics: Calcimycin; Carcinogens; Chemokine CCL2; Chemokines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; HL-60 Cells; Humans; Interleukin-8; Ionophores; Leukemia; Protein Biosynthesis; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Homocyst(e)ine induces calcium second messenger in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Collagen; Felodipine; Fluorescent Dyes; Fura-2; Glutathione; Homocysteine; Homocystine; Kinetics; Muscle, Smooth, Vascular; Neomycin; NG-Nitroarginine Methyl Ester; Pravastatin; Rats; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Differential regulation of mammalian brain-specific proline transporter by calcium and calcium-dependent protein kinases.
Topics: Amino Acid Transport Systems, Neutral; Brain Chemistry; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA, Complementary; Down-Regulation; Enzyme Activators; Enzyme Inhibitors; Humans; Indicators and Reagents; Kidney; Membrane Transport Proteins; Synaptic Transmission; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection | 2000 |
Participation of mitogen-activated protein kinase in thapsigargin- and TPA-induced histamine production in murine macrophage RAW 264.7 cells.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Flavonoids; Histamine Release; Imidazoles; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Effects of an inhibitor of myosin light chain kinase on amylase secretion from rat pancreatic acini.
Topics: Amylases; Androstadienes; Animals; Calcimycin; Calcium; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Male; Myosin-Light-Chain Kinase; Pancreas; Rats; Rats, Wistar; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 2000 |
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4.
Topics: 3T3 Cells; ADAM Proteins; ADAM17 Protein; Animals; Clone Cells; Cloning, Molecular; Colforsin; Disintegrins; Drosophila Proteins; ErbB Receptors; Kinetics; Marine Toxins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Oxazoles; Protein Isoforms; Receptor, ErbB-4; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Necrosis Factor-alpha; Vanadates | 2000 |
Direct measurement of hormone-induced acidification in intact bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Animals, Newborn; Bone and Bones; Bone Neoplasms; Bucladesine; Calcium Signaling; Carbonic Anhydrases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Mice; Organ Culture Techniques; Organ Specificity; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Second Messenger Systems; Skull; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 2000 |
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Topics: Amino Acid Sequence; Animals; Arachidonate 5-Lipoxygenase; Arsenites; Calcimycin; Cell Line; Cricetinae; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sodium Compounds; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Necrosis Factor-alpha | 2000 |
Protein kinase C potentiates capacitative Ca2+ entry that links to steroidogenesis in bovine adrenocortical cells.
Topics: Adenosine Triphosphate; Adrenal Cortex; Adrenal Cortex Hormones; Animals; Calcium; Cattle; Cells, Cultured; Manganese; Naphthalenes; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Thapsigargin suppresses phorbol ester-dependent human involucrin promoter activity by suppressing CCAAT-enhancer-binding protein alpha (C/EBPalpha) DNA binding.
Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Protein-alpha; DNA; DNA Primers; Gene Expression Regulation; Promoter Regions, Genetic; Protein Precursors; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
The effect of a Rho kinase inhibitor Y-27632 on superoxide production, aggregation and adhesion in human polymorphonuclear leukocytes.
Topics: Adult; Amides; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Superoxides; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Basal cPLA(2) phosphorylation is sufficient for Ca(2+)-induced full activation of cPLA(2) in A549 epithelial cells.
Topics: Acetophenones; Arachidonic Acid; Benzopyrans; Calcium; Cell Line; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
EGF inhibits muscarinic receptor-mediated calcium signaling in a human salivary cell line.
Topics: Binding, Competitive; Calcium; Calcium Signaling; Carbachol; Cell Line; Diglycerides; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Space; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscarinic Agonists; Muscarinic Antagonists; Phosphorylation; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Muscarinic; Salivary Glands; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Effects of elevated cytoplasmic calcium and protein kinase C on endoplasmic reticulum structure and function in HEK293 cells.
Topics: Calcium; Calcium Signaling; Cell Line; Cytophotometry; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Ionomycin; Ionophores; Kidney; Methacholine Chloride; Microscopy, Confocal; Microscopy, Electron; Muscarinic Agonists; Protein Kinase C; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection | 2000 |
Mechanisms underlying ATP-induced Ca2+ mobilization in human neutrophils.
Topics: Adenosine Triphosphate; Calcium; Humans; In Vitro Techniques; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.
Topics: Androstadienes; Bucladesine; Calcimycin; Calcineurin; Calcium; Calcium Signaling; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Kinetics; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Proteins; RGS Proteins; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2000 |
Urea signaling to ERK phosphorylation in renal medullary cells requires extracellular calcium but not calcium entry.
Topics: Animals; Calcimycin; Calcium; Cell Culture Techniques; Cell Line; Enzyme Activation; Epidermal Growth Factor; Ionomycin; Kidney Medulla; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Urea | 2001 |
Enhancing effect of tumor promoters, phorbol esters and teleocidins on nuclear receptor-mediated transcription.
Topics: Animals; Carcinogens; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Lactams; Luciferases; Lyngbya Toxins; Nuclear Receptor Subfamily 1, Group F, Member 1; Okadaic Acid; Plasmids; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Tetradecanoylphorbol Acetate; Thapsigargin; Thymidine Kinase; Trans-Activators; Transcription, Genetic; Transfection | 2000 |
Intra- and intercellular Ca(2+)-transient propagation in normal and high glucose solutions in ROS cells during mechanical stimulation.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Communication; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fluorescent Dyes; Gadolinium; Gap Junctions; Glucose; Heptanol; Microscopy, Confocal; Osteosarcoma; Protein Kinase C; Rats; Stress, Mechanical; Tetradecanoylphorbol Acetate; Thapsigargin; Verapamil | 2001 |
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcitriol; Calcium; Calmodulin; Chick Embryo; Egtazic Acid; Enzyme Activation; Fluphenazine; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Naphthalenes; Neomycin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Verapamil | 2001 |
High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells.
Topics: Antioxidants; Arachidonate 15-Lipoxygenase; Arteriosclerosis; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans; Hydrogen Peroxide; Immunoblotting; Intercellular Adhesion Molecule-1; Jurkat Cells; NF-kappa B; Oxidants; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin; Thioctic Acid; Transfection; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1999 |
Resistance to induced apoptosis in the human neuroblastoma cell line SK-N-SH in relation to neuronal differentiation. Role of Bcl-2 protein family.
Topics: Androstadienes; Apoptosis; Bacterial Proteins; Bacterial Toxins; bcl-X Protein; Biomarkers; Cell Differentiation; Cell Size; DNA Fragmentation; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Neuroblastoma; Neurons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphopyruvate Hydratase; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; rhoA GTP-Binding Protein; Signal Transduction; Staurosporine; Synaptophysin; Tetradecanoylphorbol Acetate; Thapsigargin; Tretinoin; Tumor Cells, Cultured; Wortmannin | 2001 |
Characterization of intracellular calcium oscillations induced by extracellular nucleotides in HEp-2 cells.
Topics: Adenosine Triphosphate; Aniline Compounds; Calcium Signaling; Cell Line; Enzyme Inhibitors; Estrenes; Extracellular Space; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Microscopy, Confocal; Protein Kinase C; Pyrrolidinones; Ryanodine; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Uridine Triphosphate; Xanthenes | 2000 |
HCO(3)(-) ions modify the role of PKC isoforms in the modulation of rat mast cell functions.
Topics: Animals; Bicarbonates; Biological Assay; Buffers; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Degranulation; Cell Separation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Fura-2; Histamine Release; Ionophores; Isoenzymes; Kinetics; Mast Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 2001 |
Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus.
Topics: Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Capsid; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Herpesvirus 8, Human; Humans; Indoles; Ionomycin; Maleimides; Microscopy, Electron; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Transcription, Genetic; Transfection; Viral Proteins; Virus Activation | 2001 |
Response of alkalinization or acidification by phytohemagglutinin is dependent on the activity of protein kinase C in human peripheral T Cells.
Topics: Acid-Base Equilibrium; Amiloride; Calcium; Humans; Nickel; Phytohemagglutinins; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix.
Topics: Animals; Botulinum Toxins; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Adhesion; Cell Degranulation; Cell Movement; Cell Size; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Diazoxide; Diphosphonates; Enzyme Inhibitors; Extracellular Matrix; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 2001 |
Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions.
Topics: Albumins; Antigens, CD; Cadherins; Calcium; Calcium Signaling; Carcinogens; Cell Membrane Permeability; Cells, Cultured; Cytoskeletal Proteins; Desmoplakins; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; Hemostatics; Humans; Intercellular Junctions; Iodine Radioisotopes; Isoenzymes; Myosin Light Chains; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Stress Fibers; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 2001 |
Calcium-dependent interleukin-8 gene expression in T84 human colonic epithelial cells.
Topics: Adenocarcinoma; Calcimycin; Calcineurin; Calcium; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression; Humans; Interleukin-8; Ionophores; Kinetics; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Oxytocin stimulates prostaglandin F2alpha secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C.
Topics: Animals; Calcium; Carbazoles; Dinoprost; Drug Synergism; Endometrium; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Inositol Phosphates; L-Lactate Dehydrogenase; Male; Oxytocin; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Sustained norepinephrine stimulation induces different regulation of expression in three alpha1-adrenoceptor subtypes.
Topics: Cell Line; Egtazic Acid; Genistein; Humans; Indoles; Kidney; Norepinephrine; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tyrphostins | 2001 |
Evidence for mechanistic alterations of Ca2+ homeostasis in Type 2 diabetes mellitus.
Topics: Adult; Animals; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cytosol; Diabetes Mellitus, Type 2; Endoplasmic Reticulum; Enzyme Inhibitors; Fluorescent Dyes; Homeostasis; Humans; Lymphocytes; Middle Aged; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production.
Topics: Animals; Blotting, Western; Calcium; Calcium Signaling; Cell Line; Chemokine CCL11; Chemokines, CC; Cytokines; Enzyme Activation; Gene Expression Regulation; Hybridomas; Interferon-gamma; Interleukin-4; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Thapsigargin | 2001 |
Thapsigargin-induced calcium entry and apoptotic death of neutrophils are blocked by activation of protein kinase C.
Topics: Adenosine Triphosphatases; Apoptosis; Calcium; Cell Membrane; DNA; Endonucleases; Enzyme Activation; Humans; Membrane Proteins; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 2001 |
Rat pancreatic acinar cells express a cytosolic phospholipase D1b isoform that is not regulated by cholecystokinin.
Topics: Animals; Blotting, Western; Calcium; Cell Fractionation; CHO Cells; Cholecystokinin; Cricetinae; Cytosol; Enzyme Activation; Gene Expression Regulation, Enzymologic; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Pancreas; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 2001 |
Inhibition of the calcium release-activated calcium (CRAC) current in Jurkat T cells by the HIV-1 envelope protein gp160.
Topics: Calcium; Calcium Signaling; HIV Envelope Protein gp160; HIV-1; Humans; Isoenzymes; Jurkat Cells; Kinetics; Membrane Potentials; Phytohemagglutinins; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 2002 |
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Colforsin; Gene Expression; Glycoproteins; Osteoblasts; Osteoprotegerin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Promoter Regions, Genetic; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Androgens; Apoptosis; Carrier Proteins; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Humans; Inhibitor of Apoptosis Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Male; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Cells, Cultured; Viral Proteins | 2002 |
Functional coupling of voltage-dependent L-type Ca2+ current to Ca2+-activated K+ current in pituitary GH3 cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Egtazic Acid; Electrophysiology; Enzyme Inhibitors; Indoles; Pituitary Gland; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Prolactin; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Stimulation of trehalose efflux from cockroach (Periplaneta americana) fat body by hypertrehalosemic hormone is dependent on protein kinase C and calmodulin.
Topics: Animals; Calcium; Calmodulin; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fat Body; Male; Neuropeptides; Periplaneta; Phosphorylases; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Trehalose; Trifluoperazine | 2002 |
TRH signal transduction in melanotrope cells of Xenopus laevis.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Melanocyte-Stimulating Hormones; Membrane Potentials; Piperidines; Pituitary Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyrotropin-Releasing Hormone; Xenopus laevis | 2002 |
Excitation of smooth muscles isolated from the guinea-pig gastric antrum in response to depolarization.
Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Boron Compounds; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinogens; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Guinea Pigs; Indoles; Ionophores; Lanthanum; Male; Maleimides; Muscle, Smooth; Phenanthridines; Protein Kinase C; Pyloric Antrum; Tetradecanoylphorbol Acetate; Thapsigargin | 2002 |
Epidermal growth factor-induced depletion of the intracellular Ca2+ store fails to activate capacitative Ca2+ entry in a human salivary cell line.
Topics: Calcium; Carbachol; Cell Line; Epidermal Growth Factor; Humans; Ion Transport; Recombinant Proteins; Salivary Glands; Tetradecanoylphorbol Acetate; Thapsigargin | 2002 |
Opposing effects of PKCalpha and PKCepsilon on basolateral membrane dynamics in intestinal epithelia.
Topics: Actins; Calcium; Carbazoles; Carcinogens; Cell Membrane; Cell Polarity; Cells, Cultured; Cytoskeleton; Drug Interactions; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Intestinal Mucosa; Isoenzymes; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Thapsigargin | 2002 |
Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action.
Topics: Animals; Arachidonic Acid; Araliaceae; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Isoenzymes; Lactones; Lignans; Macrophages, Peritoneal; Male; Membrane Proteins; Plant Roots; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 2002 |
Pulmonary surfactant proteins A and D directly suppress CD3+/CD4+ cell function: evidence for two shared mechanisms.
Topics: Amino Acid Sequence; Animals; Calcium; Cattle; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Cycle; Coculture Techniques; Cytosol; Down-Regulation; Epitopes, T-Lymphocyte; Growth Inhibitors; Humans; Hybridomas; Immunosuppressive Agents; Interleukin-2; Ionomycin; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Rats; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Thapsigargin | 2002 |
Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apigenin; Blotting, Western; Calcimycin; Calcium; Casein Kinase II; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Genetic Vectors; Imidazoles; Indoles; Interferon-gamma; Macrophages; Maleimides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transcriptional Activation; Tyrphostins | 2003 |
Nongenomic mechanism of glucocorticoid inhibition of bradykinin-induced calcium influx in PC12 cells: possible involvement of protein kinase C.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Blockers; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Glucocorticoids; GTP-Binding Proteins; Indoles; omega-Conotoxins; PC12 Cells; Pertussis Toxin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thapsigargin | 2003 |
Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.
Topics: Animals; Binding Sites; Calcium; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Hydrolysis; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 2003 |
Modification of intracellular free calcium in cultured A10 vascular smooth muscle cells by exogenous phosphatidic acid.
Topics: Animals; Boron Compounds; Calcium; Carbamates; Cells, Cultured; Diltiazem; Drug Interactions; Egtazic Acid; Indoles; Macrocyclic Compounds; Maleimides; Muscle, Smooth, Vascular; Oxazoles; Pertussis Toxin; Phenylcarbamates; Phosphatidic Acids; Rats; Tetradecanoylphorbol Acetate; Thapsigargin; Verapamil | 2003 |
Cholesterol depletion inhibits store-operated calcium currents and exocytotic membrane fusion in RBL-2H3 cells.
Topics: Animals; Antigens; beta-Cyclodextrins; Calcimycin; Calcium; Calcium Signaling; Cell Degranulation; Cell Line, Tumor; Cholesterol; Cyclodextrins; Down-Regulation; Exocytosis; Membrane Fusion; Membrane Microdomains; Protein Transport; Rats; src-Family Kinases; Tetradecanoylphorbol Acetate; Thapsigargin; Up-Regulation | 2003 |
Exocytosis of a complement component C3-like protein by tunicate hemocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcimycin; Carrageenan; Cell Survival; Cholera Toxin; Colchicine; Colforsin; Complement C3; Cytochalasin D; Cytoplasmic Vesicles; Enzyme-Linked Immunosorbent Assay; Exocytosis; Hemocytes; Immunohistochemistry; Kinetics; Lipopolysaccharides; Mannans; Microscopy, Electron; Phenanthridines; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Urochordata | 2004 |
Cell volume regulation in response to hypotonicity is impaired in HeLa cells expressing a protein kinase Calpha mutant lacking kinase activity.
Topics: Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Size; Chelating Agents; Cytoskeleton; Cytosol; Down-Regulation; Egtazic Acid; Endoplasmic Reticulum; Genes, Dominant; Green Fluorescent Proteins; HeLa Cells; Humans; Isoenzymes; Luminescent Proteins; Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 2004 |
Activation of human TRPC6 channels by receptor stimulation.
Topics: Calcium Channels; Carbachol; Cell Line; Cell Membrane; Cholinergic Agonists; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Humans; Ionomycin; Ionophores; Kinetics; Lac Operon; Membrane Potentials; Protein Binding; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection; TRPC Cation Channels; TRPC6 Cation Channel | 2004 |
Inhibitory effect of furosemide on activation of human peripheral blood polymorphonuclear leukocytes stimulated with n-formyl-methionyl-leucyl-phenylalanine.
Topics: Calcium; Chemotaxis, Leukocyte; Cytosol; Diuretics; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Furosemide; Humans; In Vitro Techniques; Indicators and Reagents; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phagocytosis; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Thapsigargin | 2004 |
Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.
Topics: Boron Compounds; Calcium; Calcium Channel Blockers; Cytosol; Dantrolene; Dose-Response Relationship, Drug; Estrenes; Fatty Alcohols; Glycols; HeLa Cells; Humans; Imidazoles; Indoles; Intracellular Space; Maleimides; Nickel; Nifedipine; Plasmids; Propranolol; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Leukotriene B4; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection | 2004 |
Platelet-activating factor stimulates cytoplasmic alkalinization and granule acidification in human eosinophils.
Topics: Adenosine Triphosphatases; Blotting, Western; Calcium; Cell Adhesion; Cell Membrane; Cells, Cultured; Cytoplasm; Cytoplasmic Granules; Cytosol; Eosinophil Granule Proteins; Eosinophil Major Basic Protein; Eosinophils; Esters; Fluoresceins; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Interleukin-5; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Platelet Activating Factor; Protein Kinase C; Protons; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Vacuolar Proton-Translocating ATPases; Zinc | 2004 |
M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Atropine; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Membrane Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Neurons; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Tetradecanoylphorbol Acetate; Tetrodotoxin; Thapsigargin; Zinc | 2005 |
An essential role for phospholipase D in the activation of protein kinase C and degranulation in mast cells.
Topics: 1-Butanol; Animals; Cell Degranulation; Cell Line, Transformed; Cell Line, Tumor; Diglycerides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Mast Cells; Mice; Mice, Inbred C57BL; Phosphatidic Acids; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Transport; Rats; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Thapsigargin | 2005 |
Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor.
Topics: Cell Degranulation; Cell Line, Tumor; Flow Cytometry; Granzymes; Humans; Leukemia; Lysine; Lysosomal-Associated Membrane Protein 1; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Receptors, Antigen, T-Cell; Serine Endopeptidases; Stimulation, Chemical; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thapsigargin | 2005 |
Effects of calmodulin and protein kinase C modulators on transient Ca2+ increase and capacitative Ca2+ entry in human platelets: relevant to pathophysiology of bipolar disorder.
Topics: Adult; Bipolar Disorder; Blood Platelets; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Calmodulin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Humans; Indoles; Male; Maleimides; Protein Kinase C; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin | 2007 |
The sarcoplasmic-endoplasmic reticulum Ca2+ ATPase 2b regulates the Ca2+ transients elicited by P2Y2 activation in PC Cl3 thyroid cells.
Topics: Adenosine Triphosphate; Animals; Barium; Biological Transport, Active; Calcium; Carbazoles; Cell Line; Enzyme Activation; Indoles; Maleimides; Manganese; Microscopy, Fluorescence; Protein Kinase C; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Uridine Triphosphate | 2006 |
GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-betal and plasma glucose concentration.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Activation; Glucose Transporter Type 2; Kidney; Kidney Tubules, Proximal; Male; Microvilli; Niacinamide; Organ Size; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin; Weight Gain | 2007 |
Differential effects of intravenous anesthetics on capacitative calcium entry in human pulmonary artery smooth muscle cells.
Topics: Anesthetics, Intravenous; Calcium; Calcium Channel Blockers; Calcium Channels; Carcinogens; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Muscle, Smooth, Vascular; Protein Kinase C; Protein-Tyrosine Kinases; Pulmonary Artery; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrphostins | 2008 |
ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis.
Topics: Cell Line; Enzyme Activation; Exocytosis; Extracellular Signal-Regulated MAP Kinases; Humans; Mitogen-Activated Protein Kinase Kinases; Mutation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thapsigargin | 2008 |
Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Apoptosis; Down-Regulation; Enzyme Activation; Humans; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Microscopy, Fluorescence; Neoplasms, Hormone-Dependent; Nitriles; Prostatic Neoplasms; Receptors, Androgen; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Thapsigargin; Tosyl Compounds; Tumor Cells, Cultured; Ultraviolet Rays | 2008 |
Redistribution of intracellular calcium and its effect on apoptosis in macrophages: Induction by oxidized LDL.
Topics: Apoptosis; Calcium Signaling; Cell Differentiation; Culture Media, Serum-Free; Egtazic Acid; Humans; Lipoproteins, LDL; Macrophages; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Necrosis; Tetradecanoylphorbol Acetate; Thapsigargin; U937 Cells | 2009 |
Intracellular concentrations of Ca(2+) modulate the strength of signal and alter the outcomes of cytotoxic T-lymphocyte antigen-4 (CD152)-CD80/CD86 interactions in CD4(+) T lymphocytes.
Topics: Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Calcium; Calcium-Transporting ATPases; CD3 Complex; Cell Proliferation; Cell Survival; Cells, Cultured; CTLA-4 Antigen; Female; Ionomycin; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
The mitogen-activated protein kinase phosphatase vaccinia H1-related protein inhibits apoptosis in prostate cancer cells and is overexpressed in prostate cancer.
Topics: Androgens; Apoptosis; Cell Line, Tumor; Dual Specificity Phosphatase 1; Dual Specificity Phosphatase 3; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Metribolone; Phosphorylation; Prostatic Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin | 2008 |
Stimulation of EAAC1 in C6 glioma cells by store-operated calcium influx.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Cell Line, Tumor; Excitatory Amino Acid Transporter 3; Extracellular Space; Glioma; Mice; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments.
Topics: Animals; Arsenites; Cytoplasmic Granules; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Heat-Shock Proteins; Heat-Shock Response; HeLa Cells; Heterogeneous-Nuclear Ribonucleoproteins; HSP70 Heat-Shock Proteins; Humans; Isoenzymes; Molecular Chaperones; Poly(A)-Binding Proteins; Protein Kinase C-delta; Recombinant Fusion Proteins; Stress, Physiological; T-Cell Intracellular Antigen-1; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
Calcineurin activation by slow calcium release from intracellular stores suppresses protein kinase C regulation of L-type calcium channels in L6 cells.
Topics: Animals; Calcineurin; Calcium; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cell Line; Cyclosporine; Enzyme Inhibitors; Ion Channel Gating; Ion Transport; Myoblasts, Skeletal; Phorbol Esters; Protein Kinase C; Rats; Sarcoplasmic Reticulum; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
Calcium is required for coelomocyte activation in earthworms.
Topics: Animals; Calcium; Immunity, Innate; Ionomycin; Oligochaeta; Phytohemagglutinins; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2010 |
The anti-inflammatory effect of the SOCC blocker SK&F 96365 on mouse lymphocytes after stimulation by Con A or PMA/ionomycin.
Topics: Animals; Anti-Inflammatory Agents; Antigens, CD; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Cycle; Cell Proliferation; Cells, Cultured; Concanavalin A; Cytokines; Dose-Response Relationship, Drug; Female; Fluoresceins; Fluorescent Dyes; Imidazoles; Inflammation; Ionomycin; Lymphocyte Activation; Lymphocyte Count; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Signal Transduction; Succinimides; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Effects of aegeline, a main alkaloid of Aegle Marmelos Correa leaves, on the histamine release from mast cells.
Topics: Aegle; Amides; Animals; Calcium; Cell Culture Techniques; Cell Line, Tumor; Dinitrophenols; Herb-Drug Interactions; Histamine Release; Ionomycin; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Endoplasmic reticulum stress causes EBV lytic replication.
Topics: Carcinogens; Cell Line; Cinnamates; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Epstein-Barr Virus Infections; Eukaryotic Initiation Factor-2; Gene Expression Profiling; Gene Expression Regulation, Viral; Genes, Immediate-Early; Germinal Center; Herpesvirus 4, Human; Humans; Immediate-Early Proteins; Lymphocytes; Lymphoma; Membrane Glycoproteins; Plasma Cells; Tetradecanoylphorbol Acetate; Thapsigargin; Thiourea; Trans-Activators; Viral Matrix Proteins; Virus Replication | 2011 |
Role of calcium and PKC in salivary mucous cell exocrine secretion.
Topics: Acinar Cells; Animals; Calcium; Carbachol; Diglycerides; Drug Synergism; Enzyme Activation; Isoenzymes; Mucins; Muscarinic Agonists; Protease Inhibitors; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Sublingual Gland; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 2011 |
Sulfhydryl modification induces calcium entry through IP₃-sensitive store-operated pathway in activation-dependent human neutrophils.
Topics: Adult; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Movement; Estrenes; Ethylmaleimide; Humans; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nitroprusside; Pyrrolidinones; Rats; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Acute phorbol ester treatment inhibits thapsigargin-induced cell death in porcine aortic smooth muscle cells.
Topics: Animals; Aorta; Calcium; Caspase 3; Cell Death; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thapsigargin | 2012 |
The Src kinase Yes is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters, but not pancreatic growth factors, which stimulate its association with numerous other signaling molecules.
Topics: Acinar Cells; Animals; Bombesin; Calcimycin; Calcium Ionophores; Calcium Signaling; Carbachol; Cholecystokinin; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gastrointestinal Hormones; Indoles; Intercellular Signaling Peptides and Proteins; Male; Maleimides; Neurotransmitter Agents; Pancreas; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-yes; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 2012 |
Transient receptor potential ankyrin-1 (TRPA1) modulates store-operated Ca(2+) entry by regulation of STIM1-Orai1 association.
Topics: Acetanilides; Blood Platelets; Calcium; Calcium Channels; Cell Differentiation; Cell Line; Humans; Isothiocyanates; Megakaryocytes; Membrane Proteins; Neoplasm Proteins; Nerve Tissue Proteins; ORAI1 Protein; Protein Binding; Purines; rap GTP-Binding Proteins; Stromal Interaction Molecule 1; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2013 |
Endoplasmic reticulum stress induced apoptosis and caspase activation is mediated through mitochondria during megakaryocyte differentiation.
Topics: Apoptosis; Caspases; Cell Differentiation; Endoplasmic Reticulum; Enzyme Activation; Humans; Megakaryocytes; Mitochondria; Reactive Oxygen Species; Stress, Physiological; Tetradecanoylphorbol Acetate; Thapsigargin | 2020 |
Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Apoptosis Regulatory Proteins; DNA Damage; Endoplasmic Reticulum Stress; Gene Expression Regulation; Macrolides; Oxidative Stress; Phosphoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Trans-Activators; Transcription, Genetic; Tumor Suppressor Protein p53; X-Rays; Zebrafish; Zebrafish Proteins | 2021 |