tetradecanoylphorbol acetate has been researched along with sincalide in 94 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (25.53) | 18.7374 |
| 1990's | 56 (59.57) | 18.2507 |
| 2000's | 12 (12.77) | 29.6817 |
| 2010's | 2 (2.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Camello, PJ; Render, CL; Salido, GM; Singh, J | 1 |
| Gardner, JD; Jensen, RT; Metz, DC; Mrozinski, JE; Patto, RJ; Turner, RJ | 1 |
| Gaisano, HY; Miller, LJ | 2 |
| Buchner, K; Kaufmann, R; Lindschau, C; Ott, T | 1 |
| Raffaniello, RD; Raufman, JP | 1 |
| Raufman, JP | 1 |
| Calle, R; Ganesan, S; Rasmussen, H; Zawalich, KC; Zawalich, WS | 1 |
| Kasuga, M; Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Suzuki, T; Wada, K | 1 |
| Gardner, JD; Jensen, RT; Murakami, M; Sharp, CM; Vinayek, R | 1 |
| Bastié, MJ; Williams, JA | 1 |
| Loessberg, PA; Muallem, S; Sachs, G; Zhao, H | 1 |
| de Pont, JJ; Ederveen, AG; van Emst-de Vries, SE; Willems, PH | 1 |
| Hsu, YL; Kondratenko, NF; Pandol, SJ; Schoeffield-Payne, MS; Steinbach, JH | 1 |
| Bahrami, LH; Lenhard, LW; Pandol, SJ; Perkins, PS | 1 |
| Camello, PJ; Francis, LP; Madrid, JA; Salido, GM; Singh, J | 1 |
| Buchan, AM; Curtis, SB; Meloche, RM | 1 |
| Gates, LK; Gorelick, FS; Klueppelberg, UG; Miller, LJ | 1 |
| Hasegawa, H; Kido, Y; Koide, M; Nakamura, T; Okabayashi, Y; Okutani, T; Otsuki, M | 1 |
| Muallem, S; Pandol, SJ; Sachs, G; Schoeffield, MS | 1 |
| Pandol, SJ; Schoeffield, MS | 1 |
| De Pont, JJ; Van Nooij, IG; Willems, PH | 1 |
| Kaibuchi, K; Nakanishi, H; Ohyanagi, H; Saitoh, Y; Takai, Y; Takeyama, Y | 1 |
| Ansah, TA; Case, RM; Dho, S | 1 |
| Brockenbrough, JS; Korc, M | 1 |
| de Pont, JJ; Haenen, HE; van Nooij, IG; Willems, PH | 1 |
| Cumella, J; Lee, PC; Leung, YK; Rossi, T; Srimaruta, N | 1 |
| Adachi, H; Aoki, E; Honda, T; Noguchi, M; Onishi, S; Sato, S; Torizuka, K | 1 |
| Lebenthal, E; Lee, PC; Shimizu, K | 1 |
| Hughes, RG; Matthews, EK; Rogers, J | 1 |
| Hootman, SR; Kuroiwa, C; Stuenkel, EL; Sung, CK; Williams, JA | 1 |
| Kikuchi, A; Nakanishi, H; Ohyanagi, H; Onoyama, H; Saitoh, Y; Takai, Y; Takeyama, Y | 1 |
| Gardner, JD; Jensen, RT; Menozzi, D; Sato, S | 1 |
| Brzozowski, T; Cherner, JA; Naik, L; Singh, G; Stachura, J; Tarnawski, A | 1 |
| Cherner, JA; Naik, L; Singh, G | 1 |
| De Pont, JJ; Van den Broek, BA; Van Os, CH; Willems, PH | 1 |
| Hughes, J; Lo, WW | 1 |
| Defize, J; Hunt, RH | 1 |
| Chan, CB; Soll, AH | 1 |
| Eckhardt, L; Fuller, CM; Schulz, I | 1 |
| Baba, S; Matozaki, T; Nagao, M; Sakamoto, C | 1 |
| Fimmel, CJ; Muallem, S; Pandol, SJ; Sachs, G | 1 |
| Korc, M; Magun, BE | 1 |
| De Pont, JJ; Van Emst-de Vries, SE; Willems, PH | 1 |
| Baldassare, JJ; Bastani, B; Gardner, JD; Pollo, DA; Yang, L | 1 |
| O'Konski, MS; Pandol, SJ | 1 |
| Baldassare, JJ; Gardner, JD; Henderson, PA; Honda, T; Pollo, DA; Talkad, VD | 1 |
| Chowdhury, P; Doi, R; Inoue, K; Kaji, H; Rayford, PL | 1 |
| Abraham, RT; Lutz, MP; Miller, LJ; Sutor, SL | 1 |
| Hildebrand, P; Jensen, RT; Mantey, SA; Mrozinski, JE; Patto, RJ | 1 |
| De Pont, JJ; Hoenderop, JG; Van Emst-De Vries, SE; Van Hoof, HJ; Van Mackelenbergh, MG; Willems, PH | 2 |
| Bali, JP; Gusdinar, T; Hollande, F; Magous, R | 1 |
| Kwiatkowska, K; Muallem, S; Xu, X; Yin, HL | 1 |
| Bali, JP; Cabane, S; Dornand, J; Favero, J; Magous, R; Michel, F; Roche, S | 1 |
| Gardner, JD; Huang, SC; Pandya, PK; Talkad, VD; Wank, SA | 1 |
| Foskett, JK; Gaisano, HY; Miller, LJ | 1 |
| Camello, PJ; Salido, GM | 1 |
| Gates, LK; Miller, LJ; Ulrich, CD | 1 |
| Fujii, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Dabrowski, A; Grady, T; Logsdon, CD; Williams, JA | 1 |
| Holicky, E; Madden, BJ; McCormick, DJ; Miller, LJ; Ozcelebi, F; Rao, RV | 1 |
| Akiho, H; Chijiiwa, Y; Iwakiri, Y; Motomura, Y; Nawata, H; Osame, M | 1 |
| Jensen, RT; Kitsukawa, Y; Pradhan, TK; Turner, RJ | 1 |
| Bosch, RR; De Pont, JJ; Garner, KM; Smeets, RL; Van Mackelenbergh, MG; Willems, PH | 1 |
| Bégin-Heick, N; Chakravarthy, BR; Durkin, JP; Morley, P; Wang, J; Whitfield, JF | 1 |
| Loo, DD; Prinz, C; Sachs, G | 1 |
| Hori, Y; Shinkai, M; Takeyama, Y; Ueda, T; Yamamoto, M | 1 |
| García, LJ; González, A; Jensen, RT; Rosado, JA | 1 |
| De Pont, JJ; Miller, LJ; Rao, RV; Smeets, RL; van Emst-de Vries, SE; Willems, PH | 1 |
| Padfield, PJ; Panesar, N | 1 |
| Akiyama, T; Hirohata, Y; Ogami, Y; Otsuki, M; Shibuya, I | 1 |
| De Pont, JJ; Fouraux, MA; Smeets, RL; van Emst-de Vries, SE; Willems, PH | 1 |
| Henklein, P; Kaufmann, R; Nowak, G; Schafberg, H; Zieger, M | 1 |
| De Pont, JJ; Fouraux, MA; Pouwels, W; Ronken, E; Smeets, RL; van Emst-de Vries, SE; Willems, PH | 1 |
| Ahrén, B; Karlsson, S; Simonsson, E | 1 |
| Garcia, LJ; Jensen, RT; Rosado, JA; Salido, GM | 1 |
| Akiyama, T; Hirohata, Y; Imoto, I; Okabayashi, Y; Otsuki, M | 1 |
| Bosch, RR; de Pont, HH; Emst-de Vries, SE; Joep, J; Patel, AM; Sleutels, F; Smeets, RL; Willems, PH | 1 |
| Ferris, HA; García, LJ; Jensen, RT; Tapia, JA | 1 |
| Chijiiwa, Y; Motomura, Y; Nawata, H; Ochiai, T; Yasuda, O | 1 |
| Hayakawa, T; Ishiguro, H; Kitagawa, M; Mizuno, N; Naruse, S | 1 |
| Grider, JR; Makhlouf, GM; Murthy, KS | 1 |
| Claro, E; Ramos, B; Salido, G; Sarri, E | 1 |
| Chijiiwa, Y; Harada, N; Motomura, Y; Nawata, H; Ochiai, T; Yasuda, O | 1 |
| Bosch, RR; De Pont, JJ; Harris, AB; van Emst-de Vries, SE; Willems, PH | 1 |
| Carstens, OC; Fölsch, UR; Günther, R; Schmidt, WE | 1 |
| Bragado, MJ; García-Marin, LJ; Jensen, RT; Pace, A; Tapia, JA | 1 |
| García-Marin, LJ; Jensen, RT; Tapia, JA | 1 |
| Kunert, J; Lüthen, F; Siegmund, E; Weber, H | 1 |
| Cai, K; Chen, Q; Cheng, Z; Liu, F; Wu, C; Xiao, H; Yang, X; Zhou, X | 1 |
| Dabrowski, A; Daniluk, J | 1 |
| Jensen, RT; Nuche-Berenguer, B; Sancho, V | 1 |
| Gong, YY; Lin, L; Lu, J; Si, XM | 1 |
94 other study(ies) available for tetradecanoylphorbol acetate and sincalide
| Article | Year |
|---|---|
Secretagogue-evoked time-course changes on pancreatic juice secretion in the anaesthetized rat.
Topics: Amylases; Animals; Dose-Response Relationship, Drug; Drug Interactions; Female; Infusions, Intravenous; Kinetics; Male; Pancreatic Juice; Polymyxin B; Proteins; Rats; Rats, Inbred Strains; Secretin; Sincalide; Tetradecanoylphorbol Acetate | 1992 |
Thapsigargin defines the roles of cellular calcium in secretagogue-stimulated enzyme secretion from pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Carbachol; Cytoplasm; Fura-2; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Secretin; Sincalide; Spectrometry, Fluorescence; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoactive Intestinal Peptide | 1992 |
Complex role of protein kinase C in mediating the supramaximal inhibition of pancreatic secretion observed with cholecystokinin.
Topics: Animals; Bombesin; Carbachol; Cholecystokinin; Enzyme Activation; Male; Pancreas; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Temperature; Tetradecanoylphorbol Acetate | 1992 |
CCKB receptor stimulation mediates [Ca2+]i increase but no PKC activation in Jurkat T-cells.
Topics: Benzodiazepinones; Calcium; Cell Line; Devazepide; Enzyme Activation; Humans; Kinetics; Phenylurea Compounds; Protein Kinase C; Receptors, Cholecystokinin; Sincalide; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Cellular distribution of gastric chief cell protein kinase C activity: differential effects of diacylglycerol, phorbol esters, carbachol, and cholecystokinin.
Topics: Animals; Carbachol; Diglycerides; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; Male; Pepsinogens; Protein Kinase C; Sincalide; Tetradecanoylphorbol Acetate | 1992 |
Actions of phorbol esters on levels of cAMP in cholera toxin-treated chief cells from guinea pig stomach.
Topics: Animals; Calcimycin; Calmodulin; Carbachol; Cholera Toxin; Gastric Mucosa; Guinea Pigs; Imidazoles; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Phorbols; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1992 |
Effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on islet-cell responsiveness.
Topics: Animals; Calcimycin; Calcium; Glucose; Immunoblotting; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitrendipine; Phosphatidylinositols; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Tolbutamide | 1991 |
Cholecystokinin inhibits phosphatidylcholine synthesis via a Ca(2+)-calmodulin-dependent pathway in isolated rat pancreatic acini. A possible mechanism for diacylglycerol accumulation.
Topics: Alkaloids; Animals; Bombesin; Bucladesine; Calcimycin; Calcium; Calmodulin; Carbachol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diglycerides; In Vitro Techniques; Kinetics; Male; Nucleotidyltransferases; Pancreas; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretin; Sincalide; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Carbachol desensitizes pancreatic enzyme secretion by downregulation of receptors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Carbachol; Cycloheximide; Down-Regulation; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Pancreas; Receptors, Cell Surface; Sincalide; Substance P; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1990 |
Gastrointestinal peptides activate Na(+)-H+ exchanger in AR42J cells by increasing its affinity for intracellular H+.
Topics: Amiloride; Amino Acid Sequence; Animals; Bombesin; Carbachol; Carrier Proteins; Cell Line; Gastrointestinal Hormones; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Pancreatic Neoplasms; Pentagastrin; Rats; Sincalide; Sodium Chloride; Sodium-Hydrogen Exchangers; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Regulation of intracellular Ca2+ oscillation in AR42J cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Line; Kinetics; Oscillometry; Pancreas; Sincalide; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Effects of phorbol ester and cholecystokinin on the intracellular distribution of protein kinase C in rabbit pancreatic acini.
Topics: Amylases; Animals; Cell Fractionation; Diacylglycerol Kinase; Kinetics; Pancreas; Phosphotransferases; Protein Kinase C; Pyrimidinones; Rabbits; Sincalide; Subcellular Fractions; Tetradecanoylphorbol Acetate; Thiazoles | 1991 |
Dual pathways for agonist-stimulated arachidonic acid release in pancreatic acini: roles in secretion.
Topics: Amylases; Animals; Arachidonic Acids; Cyclohexanones; Diglycerides; Fatty Acids; Guinea Pigs; In Vitro Techniques; Kinetics; Lipoprotein Lipase; Lysophosphatidylcholines; Pancreas; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Sincalide; Tetradecanoylphorbol Acetate | 1991 |
Intracellular mechanisms involved in short-term regulation of net protein synthesis in pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Calcimycin; Carbachol; DNA Probes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzymes; Isoquinolines; Lipase; Nucleic Acid Hybridization; Pancreas; Pancreatic Elastase; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Effects of phorbol ester on cholecystokinin octapeptide-evoked exocrine pancreatic secretion in the rat.
Topics: Amylases; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Pancreas; Pancreatic Juice; Polymyxin B; Proteins; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Release of somatostatin immunoreactivity from human antral D cells in culture.
Topics: Adult; Bombesin; Calcimycin; Cells, Cultured; Colforsin; Female; Gastric Mucosa; Gastrins; Humans; Male; Pyloric Antrum; Radioimmunoassay; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1990 |
Agonist-regulated phosphorylation of the pancreatic cholecystokinin receptor.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cell Fractionation; Chromatography, Affinity; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Kinetics; Male; Pancreas; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Solubility; Tetradecanoylphorbol Acetate | 1991 |
Regulatory effect of cholecystokinin on subsequent insulin binding to pancreatic acini.
Topics: Animals; Binding, Competitive; Calcimycin; Carbachol; Cell Membrane; Insulin; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptor, Insulin; Sincalide; Tetradecanoylphorbol Acetate | 1990 |
Role of free cytosolic calcium in secretagogue-stimulated amylase release from dispersed acini from guinea pig pancreas.
Topics: Amylases; Animals; Bombesin; Calcimycin; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Kinetics; Pancreas; Pancreatic Juice; Sincalide; Tetradecanoylphorbol Acetate | 1985 |
1,2-Diacylglycerol, protein kinase C, and pancreatic enzyme secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Arachidonic Acid; Arachidonic Acids; Bombesin; Calcimycin; Carbachol; Dibutyryl Cyclic GMP; Diglycerides; Glycerides; Guinea Pigs; In Vitro Techniques; Isoquinolines; Kinetics; Pancreas; Piperazines; Protein Kinase C; Sincalide; Tetradecanoylphorbol Acetate; Tetragastrin | 1986 |
Stimulatory and inhibitory effects of TMB-8 on pancreatic enzyme secretion.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Gallic Acid; L-Lactate Dehydrogenase; Pancreas; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Enhancement of secretagogue-induced phosphoinositide turnover and amylase secretion by bile acids in isolated rat pancreatic acini.
Topics: Amylases; Animals; Bile Acids and Salts; Calcium; Deoxycholic Acid; Diglycerides; Dose-Response Relationship, Drug; In Vitro Techniques; Male; N-Methylscopolamine; Octoxynol; Pancreas; Pancreatitis; Phosphatidylinositols; Polyethylene Glycols; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Calcium concentration and amylase secretion in guinea pig pancreatic acini: interactions between carbachol, cholecystokinin octapeptide and the phorbol ester, 12-O-tetradecanoylphorbol 13-acetate.
Topics: Amylases; Animals; Calcium; Carbachol; Guinea Pigs; Pancreas; Phorbol Esters; Protein Kinase C; Secretory Rate; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Effects of 1-oleoyl-2-acetyl glycerol are distinct from those of phorbol ester in rat pancreatic acini.
Topics: Amylases; Animals; Biological Transport; Calcimycin; Carbachol; Diglycerides; Enzyme Activation; ErbB Receptors; Glycerides; In Vitro Techniques; Male; Pancreas; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester inhibits cholecystokinin octapeptide-induced amylase secretion and calcium mobilization, but is without effect on secretagogue-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in rabbit pancreatic acini.
Topics: Amylases; Animals; Calcium; Hydrolysis; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester attenuates cholecystokinin-stimulated amylase release in pancreatic acini of rats.
Topics: Amylases; Animals; Calcimycin; Carbachol; Enzyme Activation; Kinetics; Male; Pancreas; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1987 |
Effect of AA861, a 5-lipoxygenase inhibitor, on amylase secretion from rat pancreatic acini.
Topics: Amylases; Animals; Arachidonate Lipoxygenases; Benzoquinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; In Vitro Techniques; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Male; Pancreas; Quinones; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Immature stimulus-secretion coupling in the developing exocrine pancreas and ontogenic changes of protein kinase C.
Topics: Amylases; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cytosol; Fetus; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Secretory Rate; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Cyclic GMP inhibits protein kinase C-mediated secretion in rat pancreatic acini.
Topics: Amylases; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cyclic GMP; Dibutyryl Cyclic GMP; In Vitro Techniques; Kinetics; Pancreas; Pancreatic Juice; Protein Kinase C; Rats; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Downregulation of protein kinase C in guinea pig pancreatic acini: effects on secretion.
Topics: Amylases; Animals; Calcimycin; Carbachol; Guinea Pigs; Male; Osmolar Concentration; Pancreas; Protein Kinase C; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Mode of inhibitory action of cholecystokinin in amylase release from isolated rat pancreatic acini--inhibition of secretory process post to protein kinase C-calcium ion systems.
Topics: Amylases; Animals; Calcimycin; Calcium; Drug Synergism; In Vitro Techniques; Male; Pancreas; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Cyclic GMP does not inhibit protein kinase C-mediated enzyme secretion in rat pancreatic acini.
Topics: Amylases; Animals; Bombesin; Calcimycin; Carbachol; Cyclic GMP; Dibutyryl Cyclic GMP; In Vitro Techniques; Kinetics; Male; Nitroprusside; Pancreas; Protein Kinases; Rats; Rats, Inbred Strains; Reference Values; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1989 |
Ability of prostaglandin to reduce ethanol injury to dispersed chief cells from guinea pig stomach.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Carbachol; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Colforsin; Ethanol; Female; Gastric Mucosa; Guinea Pigs; L-Lactate Dehydrogenase; Microscopy, Electron; Microscopy, Electron, Scanning; Pepsinogens; Prostaglandins E, Synthetic; Rosaniline Dyes; Sincalide; Tetradecanoylphorbol Acetate | 1989 |
Cholecystokinin-induced desensitization of pepsinogen secretion from chief cells.
Topics: Animals; Calcimycin; Calcium; Female; Gastric Mucosa; Guinea Pigs; Pepsinogens; Receptors, Cholecystokinin; Sincalide; Temperature; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release in permeabilized pancreatic acinar cells by hormonal and phorbol ester pretreatment.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Carbachol; Cell Membrane Permeability; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Pancreas; Piperazines; Protein Kinase Inhibitors; Rabbits; Sincalide; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1989 |
Differential regulation of cholecystokinin- and muscarinic-receptor-mediated phosphoinositide turnover in Flow 9000 cells.
Topics: Acetylcholine; Cell Line; Guanosine Triphosphate; Humans; Inositol Phosphates; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Cholecystokinin; Receptors, Muscarinic; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Control of pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells.
Topics: Animals; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Culture Media; Dogs; Gastric Mucosa; In Vitro Techniques; Pepsinogens; Sincalide; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1988 |
Pertussis toxin-sensitive cholinergic inhibition of somatostatin release from canine D-cells.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Cells, Cultured; Colforsin; Dogs; Epinephrine; Gastric Fundus; Gastric Mucosa; Kinetics; Pertussis Toxin; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Ionic and osmotic dependence of secretion from permeabilised acini of the rat pancreas.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Carbachol; Chlorides; In Vitro Techniques; Male; Osmosis; Pancreas; Potassium; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1989 |
Combined effect of phorbol ester and, A23187 or dibutyryl cyclic AMP on pepsinogen secretion from isolated gastric glands.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; Guinea Pigs; Pepsinogens; Phorbols; Protein Kinase C; Protein Kinases; Sincalide; Tetradecanoylphorbol Acetate | 1985 |
Regulation of free cytosolic Ca2+ in the peptic and parietal cells of the rabbit gastric gland.
Topics: Aminopyrine; Aminoquinolines; Animals; Atropine; Bombesin; Bucladesine; Calcimycin; Calcium; Calcium Chloride; Carbachol; Cytosol; Gastric Mucosa; Lanthanum; Nifedipine; Parietal Cells, Gastric; Pepsin A; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Residual inhibition of epidermal growth factor binding by pancreatic secretagogues and phorbol ester in rat pancreas.
Topics: Animals; Bombesin; Calcium; Carbachol; Dibutyryl Cyclic GMP; Epidermal Growth Factor; Kinetics; Male; Pancreas; Phorbol Esters; Proglumide; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1985 |
Cholecystokinin-stimulated enzyme secretion from dispersed rabbit pancreatic acinar cells: phosphorylation-dependent changes in potency and efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amylases; Animals; Calcium-Transporting ATPases; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Pancreas; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sincalide; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1995 |
Cellular distribution of isoforms of protein kinase C (PKC) in pancreatic acini.
Topics: Animals; Cell Compartmentation; Cell Membrane; Diglycerides; Fluorescent Antibody Technique, Indirect; Isoenzymes; Pancreas; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate | 1995 |
Cholecystokinin JMV-180 and caerulein effects on the pancreatic acinar cell cytoskeleton.
Topics: Amylases; Animals; Bombesin; Calcium; Ceruletide; Cytoskeleton; Diglycerides; Enzyme Activation; Microscopy, Electron; Pancreas; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
Effects of cholecystokinin (CCK) and other secretagogues on isoforms of protein kinase C (PKC) in pancreatic acini.
Topics: Amylases; Animals; Benzodiazepinones; Carbachol; Cholecystokinin; Devazepide; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Immunoblotting; In Vitro Techniques; Isoenzymes; Pancreas; Protein Kinase C; Rats; Receptors, Cholecystokinin; Sincalide; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1994 |
Structural and functional changes of exocrine pancreas induced by FK506 in rats.
Topics: Amylases; Analysis of Variance; Animals; Atropine; Body Weight; Calcimycin; Calcium; Carbachol; Cholecystokinin; Colforsin; Cytosol; Dose-Response Relationship, Drug; Feeding Behavior; Kinetics; Male; N-Methylscopolamine; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reference Values; Scopolamine; Scopolamine Derivatives; Secretin; Sincalide; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Trypsinogen; Vasoactive Intestinal Peptide | 1993 |
A role for cholecystokinin-stimulated protein tyrosine phosphorylation in regulated secretion by the pancreatic acinar cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Cells, Cultured; Cholecystokinin; Genistein; Isoflavones; Isoquinolines; Kinetics; Male; Pancreas; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Benzodiazepinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; Cyclic AMP; Devazepide; Endothelins; Enzyme Activation; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasoactive Intestinal Peptide | 1993 |
Receptor-evoked Ca2+ mobilization in pancreatic acinar cells: evidence for a regulatory role of protein kinase C by a mechanism involving the transition of high-affinity receptors to a low-affinity state.
Topics: Alkaloids; Animals; Brain; Calcium; Carbachol; Cholecystokinin; Fura-2; Inosine Triphosphate; Naphthalenes; Pancreas; Phosphorylation; Polycyclic Compounds; Proglumide; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Neurohormonal regulation of histamine release from isolated rabbit fundic mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine Release; Male; Muscarinic Antagonists; Prostaglandins; Rabbits; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells.
Topics: Actins; Animals; Calcium; Carbachol; Cell Membrane Permeability; Cytoskeleton; Exocytosis; Gelsolin; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Pancreas; Polymers; Rats; Sincalide; Streptolysins; Tetradecanoylphorbol Acetate; Thymosin | 1995 |
Gastrin-CCK-B type receptors on human T lymphoblastoid Jurkat cells.
Topics: Calcium; Cell Line; Gastrins; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-2; Iodine Radioisotopes; Pentagastrin; Receptors, Cholecystokinin; Sincalide; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Low concentrations of protein kinase C-activating agonists suppress cholecystokinin-OPE-evoked Ca2+ mobilization in rat pancreatic acini.
Topics: Animals; Calcium; Cholecystokinin; Enzyme Activation; Male; Pancreas; Peptide Fragments; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate | 1994 |
Biochemical regulation of the three different states of the cholecystokinin (CCK) receptor in pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzodiazepinones; Bombesin; Carbachol; Cholecystokinin; Devazepide; GTP-Binding Proteins; In Vitro Techniques; Isoquinolines; Pancreas; Phosphorylation; Piperazines; Rats; Receptors, Cholecystokinin; Secretin; Sincalide; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1994 |
Suppression of Ca2+ oscillations induced by cholecystokinin (CCK) and its analog OPE in rat pancreatic acinar cells by low-level protein kinase C activation without transition of the CCK receptor from a high- to low-affinity state.
Topics: Amino Acid Sequence; Animals; Calcium; Cholecystokinin; Enzyme Activation; Male; Molecular Sequence Data; Pancreas; Peptide Fragments; Protein Kinase C; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate | 1994 |
CCK8-evoked Ca2+ mobilization in pancreatic acinar cells. Evidence for a regulatory role of protein kinase C by phosphorylation-dependent inhibition of signaling through the high-affinity CCK receptor.
Topics: Animals; Calcium; In Vitro Techniques; Kinetics; Pancreas; Phosphorylation; Protein Kinase C; Rabbits; Receptors, Cholecystokinin; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1994 |
Inhibitory interactions between stimulus-secretion pathways in the exocrine rat pancreas.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Models, Biological; Pancreas; Proteins; Rats; Secretin; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1993 |
Multiple kinases phosphorylate the pancreatic cholecystokinin receptor in an agonist-dependent manner.
Topics: Alkaloids; Animals; beta-Adrenergic Receptor Kinases; Carbachol; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; In Vitro Techniques; Isoenzymes; Kinetics; Male; Pancreas; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Chronic oral administration of synthetic trypsin inhibitor camostate reduces amylase release from isolated rat pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Oral; Amylases; Animals; Calcimycin; Carbachol; Cholecystokinin; Esters; Gabexate; Guanidines; In Vitro Techniques; Male; Pancreas; Rats; Rats, Wistar; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Trypsin Inhibitors | 1995 |
Jun kinases are rapidly activated by cholecystokinin in rat pancreas both in vitro and in vivo.
Topics: Animals; Anisomycin; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell-Free System; Ceruletide; Cholecystokinin; Enzyme Activation; Enzyme Inhibitors; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Male; Mitogen-Activated Protein Kinases; Pancreas; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1996 |
Phosphorylation of cholecystokinin receptors expressed on Chinese hamster ovary cells. Similarities and differences relative to native pancreatic acinar cell receptors.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cholecystokinin; Chromatography, High Pressure Liquid; Cricetinae; Electrophoresis, Polyacrylamide Gel; Models, Structural; Molecular Sequence Data; Pancreas; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Structure, Secondary; Rats; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Direct inhibitory effect of corticotropin releasing hormone on isolated caecal circular smooth muscle cells of guinea pig via adenylate cyclase system.
Topics: Adenylyl Cyclase Inhibitors; Aminoquinolines; Animals; Cecum; Corticotropin-Releasing Hormone; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Sincalide; Tetradecanoylphorbol Acetate | 1996 |
Gastric chief cells possess NK1 receptors which mediate pepsinogen secretion and are regulated by agents that increase cAMP and phospholipase C.
Topics: Animals; Binding, Competitive; Calcium; Cyclic AMP; Endocytosis; Gastric Mucosa; Guinea Pigs; Kinetics; Male; Neurokinin-1 Receptor Antagonists; Pepsinogens; Peptides; Protein Binding; Receptors, Neurokinin-1; Secretin; Sincalide; Substance P; Tachykinins; Temperature; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Protein kinase C activation inhibits receptor-evoked inositol trisphosphate formation and induction of cytosolic calcium oscillations by decreasing the affinity-state of the cholecystokinin receptor in pancreatic acinar cells.
Topics: Animals; Calcium; Cytosol; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Pancreas; Periodicity; Protein Kinase C; Rabbits; Receptors, Cholecystokinin; Signal Processing, Computer-Assisted; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1995 |
Glucose, potassium, and CCK-8 induce increases in membrane-associated PKC activity that correspond to increases in [Ca2+]i in islet cells from neonatal rats.
Topics: Animals; Animals, Newborn; Calcium; Cell Membrane; Cells, Cultured; Female; Glucose; Islets of Langerhans; Lanthanum; Male; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate | 1996 |
Potassium and chloride currents in rat gastric enterochromaffin-like cells.
Topics: Animals; Cells, Cultured; Chlorides; Chromaffin System; Electric Conductivity; Female; Gastrins; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley; Sincalide; Stomach; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory action of sphingosine or ceramide on amylase secretion from isolated rat pancreatic acini.
Topics: Amylases; Animals; Calcimycin; Carbachol; In Vitro Techniques; Male; Pancreas; Rats; Rats, Wistar; Sincalide; Sodium Fluoride; Sphingosine; Tetradecanoylphorbol Acetate | 1997 |
Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho.
Topics: Actins; Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Models, Biological; Pancreas; Paxillin; Phospholipases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; rho GTP-Binding Proteins; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
Reduced cholecystokinin receptor phosphorylation and restored signalling in protein kinase C down-regulated rat pancreatic acinar cells.
Topics: Animals; Calcium; Cytosol; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Immunoblotting; Isoenzymes; Kinetics; Pancreas; Phosphorylation; Protein Kinase C; Rats; Receptors, Cholecystokinin; Signal Transduction; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Cholecystokinin octapeptide inhibits Ca2+-dependent amylase secretion from permeabilized pancreatic acini by blocking the MgATP-dependent priming of exocytosis.
Topics: Adenosine Triphosphate; Amylases; Animals; Calcium; Enzyme Inhibitors; Exocytosis; Pancreas; Pancreatic Juice; Protein Kinase C; Rats; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Stimulatory effects of vanadate on amylase release from isolated rat pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcium; Carbachol; Drug Interactions; Enzyme Activation; Ion Transport; Male; Pancreas; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Sincalide; Subcellular Fractions; Tetradecanoylphorbol Acetate; Vanadates; Vasoactive Intestinal Peptide | 1998 |
Protein kinase C-mediated inhibition of transmembrane signalling through CCK(A) and CCK(B) receptors.
Topics: Animals; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Down-Regulation; Protein Kinase C; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Recombinant Proteins; Signal Transduction; Sincalide; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tritium | 1998 |
Protein kinase C is involved in cholecystokinin octapeptide-induced proliferative action in rat glioma C6 cells.
Topics: Animals; Blotting, Western; Carcinogens; Enzyme Activation; Glioma; Isoenzymes; Protein Kinase C; Protein Kinase C beta; Rats; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tumor Cells, Cultured | 1998 |
Mutational analysis of the potential phosphorylation sites for protein kinase C on the CCK(A) receptor.
Topics: Amino Acid Sequence; Animals; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Kinase C; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Tetradecanoylphorbol Acetate | 1998 |
Ca2+-independent phospholipase A2 contributes to the insulinotropic action of cholecystokinin-8 in rat islets: dissociation from the mechanism of carbachol.
Topics: Animals; Arachidonic Acid; Carbachol; Cells, Cultured; Cinnamates; Group VI Phospholipases A2; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lysophosphatidylcholines; Male; ortho-Aminobenzoates; Palmitic Acid; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Sincalide; Tetradecanoylphorbol Acetate; Verapamil | 1998 |
Are tyrosine phosphorylation of p125(FAK) and paxillin or the small GTP binding protein, rho, needed for CCK-stimulated pancreatic amylase secretion?
Topics: ADP Ribose Transferases; Amylases; Animals; Botulinum Toxins; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin D; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; GTP-Binding Proteins; Male; Pancreas; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Supramaximal CCK and CCh concentrations abolish VIP potentiation by inhibiting adenylyl cyclase activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Amylases; Animals; Bombesin; Carbachol; Cell Membrane; Cholecystokinin; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Kinetics; Male; Pancreas; Pilocarpine; Rats; Rats, Wistar; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1998 |
Concerted action of cytosolic Ca2+ and protein kinase C in receptor-mediated phospholipase D activation in Chinese hamster ovary cells expressing the cholecystokinin-A receptor.
Topics: Alkaloids; Animals; Benzophenanthridines; Brain; Calcium; CHO Cells; Cricetinae; Cytosol; Down-Regulation; Enzyme Activation; Glycerophospholipids; Phenanthridines; Phospholipase D; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Recombinant Proteins; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Calcimycin; Calcium; Cell Adhesion Molecules; Cholecystokinin; Colchicine; Cytochalasin D; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Models, Biological; Pancreas; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 1999 |
Interaction between brain natriuretic peptide and atrial natriuretic peptide in caecal circular smooth muscle cells.
Topics: Aminoquinolines; Animals; Atrial Natriuretic Factor; Binding Sites; Cecum; Cyclic AMP; Guinea Pigs; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Natriuretic Peptide, Brain; Peptide Fragments; Sincalide; Tetradecanoylphorbol Acetate; Thionucleotides | 2000 |
Effects of an inhibitor of myosin light chain kinase on amylase secretion from rat pancreatic acini.
Topics: Amylases; Androstadienes; Animals; Calcimycin; Calcium; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Male; Myosin-Light-Chain Kinase; Pancreas; Rats; Rats, Wistar; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 2000 |
Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G(i-1) and G(i-2).
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Hormones; Isoenzymes; Muscle, Smooth; Naphthalenes; Phospholipase C beta; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Rabbits; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2000 |
Cholecystokinin octapeptide CCK-8 and carbachol reduce [(32)P]orthophosphate labeling of phosphatidylcholine without modifying phospholipase D activity in rat pancreatic acini.
Topics: Animals; Butanols; Carbachol; Enzyme Activation; Ethanol; Glycerophospholipids; Hydrogen Peroxide; Kinetics; Pancreas; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Rats; Rats, Wistar; Sincalide; Tetradecanoylphorbol Acetate; Vanadates | 2000 |
Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells.
Topics: Adrenomedullin; Aminoquinolines; Amyloid; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Cholecystokinin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; Humans; Inhibitory Concentration 50; Islet Amyloid Polypeptide; Kinetics; Muscle Contraction; Muscle, Smooth; Peptides; Sincalide; Tetradecanoylphorbol Acetate; Thionucleotides | 2001 |
Rat pancreatic acinar cells express a cytosolic phospholipase D1b isoform that is not regulated by cholecystokinin.
Topics: Animals; Blotting, Western; Calcium; Cell Fractionation; CHO Cells; Cholecystokinin; Cricetinae; Cytosol; Enzyme Activation; Gene Expression Regulation, Enzymologic; Guanosine 5'-O-(3-Thiotriphosphate); Isoenzymes; Pancreas; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 2001 |
Transient agonist-induced regulation of the cholecystokinin-A and cholecystokinin-B receptor mRNA levels in rat pancreatic acinar AR42J cells.
Topics: Animals; Benzodiazepinones; Bucladesine; Cell Line; Colforsin; Dactinomycin; Down-Regulation; Gastrins; Pancreas; Phenylurea Compounds; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Sincalide; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.
Topics: Animals; Binding Sites; Calcium; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Hydrolysis; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 2003 |
Cholecystokinin-stimulated protein kinase C-delta kinase activation, tyrosine phosphorylation, and translocation are mediated by Src tyrosine kinases in pancreatic acinar cells.
Topics: Animals; Cell Fractionation; Cell Membrane; Cell Nucleus; Cytosol; Enzyme Activation; Enzyme Inhibitors; Kinetics; Male; Pancreas; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Rats, Wistar; Sincalide; src-Family Kinases; Tetradecanoylphorbol Acetate; Tyrphostins | 2003 |
Ethanol modifies the actin cytoskeleton in rat pancreatic acinar cells--comparison with effects of CCK.
Topics: Actins; alpha-Amylases; Animals; Cytoskeleton; Enzyme Activation; Enzyme Inhibitors; Ethanol; Female; L-Lactate Dehydrogenase; Pancreas; Protein Kinase C; Rats; Rats, Inbred Lew; Sincalide; Tetradecanoylphorbol Acetate | 2004 |
Effect of protein kinase C on proliferation and apoptosis of T lymphocytes in idiopathic thrombocytopenic purpura children.
Topics: Adolescent; Apoptosis; Case-Control Studies; Cell Proliferation; Child; Child, Preschool; DNA Fragmentation; Fas Ligand Protein; Female; Flow Cytometry; Humans; Infant; Male; Membrane Glycoproteins; Protein Kinase C; Purpura, Thrombocytopenic, Idiopathic; Sincalide; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factors | 2005 |
The effect of concomitant stimulation with cholecystokinin and epidermal growth factor on extracellular signal-regulated kinase (ERK) activity in pancreatic acinar cells.
Topics: Animals; Blotting, Western; Carbachol; Cholecystokinin; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Male; Muscarinic Agonists; Pancreas, Exocrine; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sincalide; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
The Src kinase Yes is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters, but not pancreatic growth factors, which stimulate its association with numerous other signaling molecules.
Topics: Acinar Cells; Animals; Bombesin; Calcimycin; Calcium Ionophores; Calcium Signaling; Carbachol; Cholecystokinin; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gastrointestinal Hormones; Indoles; Intercellular Signaling Peptides and Proteins; Male; Maleimides; Neurotransmitter Agents; Pancreas; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-yes; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 2012 |
Mechanisms of cholecystokinin-induced calcium mobilization in gastric antral interstitial cells of Cajal.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Chemokines, CC; Cholecystokinin; Female; Fluorometry; Inositol 1,4,5-Trisphosphate Receptors; Interstitial Cells of Cajal; Male; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microscopy, Fluorescence; Peptide Fragments; Phosphorylation; Protein Kinase C; Pyloric Antrum; Receptors, Cholecystokinin; Tetradecanoylphorbol Acetate | 2012 |