tetradecanoylphorbol acetate has been researched along with serine in 253 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (5.93) | 18.7374 |
| 1990's | 94 (37.15) | 18.2507 |
| 2000's | 114 (45.06) | 29.6817 |
| 2010's | 30 (11.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adler, V; Kraft, AS; Polotskaya, A; Wagner, F | 1 |
| Park, D; Rhee, SG | 1 |
| Kanfer, JN; Massarelli, R; McCartney, DG; Singh, IN; Sorrentino, G | 1 |
| Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D | 1 |
| Lammers, R; Pillay, TS; Siddle, K; Ullrich, A; Whittaker, J | 1 |
| Anderson, CW; Hickey, E; Lambert, H; Landry, J; Lavoie, JN; Weber, LA; Zhou, M | 1 |
| Brautigan, DL; Clark, EA; Gallis, B; Ledbetter, JA; Pinault, F; Valentine, MA; Voice, R; Widmer, MB | 1 |
| Doyle, C; Kappes, D; Shin, J; Strominger, JL; Yang, Z | 1 |
| Deuel, TF; Shawver, LK | 1 |
| Bussolino, F; Comoglio, PM; Di Renzo, MF; Gandino, L; Giordano, S | 1 |
| Fields, AP; Kraft, AS; May, WS; Tyler, G | 1 |
| Benjamin, TL; Matthews, JT | 1 |
| Chaffin, KE; Gentry, LE; Purchio, AF; Shoyab, M | 1 |
| Choi, JK; Shalloway, D; Yaciuk, P | 1 |
| Dobashi, K; Greene, MI; Weiner, DB | 1 |
| Buss, JE; Cooper, JA; Gould, KL; Hunter, T; Shalloway, D; Woodgett, JR | 1 |
| Caron, MG; Cotecchia, S; DeBlasi, A; Leeb-Lundberg, LM; Lefkowitz, RJ | 1 |
| Hoffbrand, AV; Mire, AR; Wickremasinghe, RG | 1 |
| Hachiya, HL; King, GL; Takayama, S; White, MF | 1 |
| Davis, RJ; Meisner, H | 1 |
| Kahn, CR; Takayama, S; White, MF | 1 |
| Pendergast, AM; Traugh, JA; Witte, ON | 1 |
| Dunn, KW; Maxfield, FR; McGraw, TE | 1 |
| Creutz, CE; Summers, TA | 1 |
| Bishop, R; Martinez, R; Nakamura, KD; Weber, MJ | 1 |
| Bauer, H; Friis, RR; Tamura, T | 1 |
| Garton, AJ; Tonks, NK | 1 |
| Ernst, MK; Israël, A; Laurent-Winter, C; LeBail, O; Rice, N; Whiteside, ST | 1 |
| Ehlers, MD; Huganir, RL; Tingley, WG | 1 |
| Ali, H; DuBose, RA; Haribabu, B; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Bannai, S; Fujiwara, K; Sagara, J; Sato, H | 1 |
| Brown, K; Kanno, T; Siebenlist, U | 1 |
| Ascoli, M; Hipkin, RW; Wang, Z | 1 |
| Chap, H; Gaits, F; Li, RY; Ragab, A; Ragab-Thomas, JM | 1 |
| den Hertog, J; Kruijer, W; Pals, CE; Sap, J; Schlessinger, J | 1 |
| Baeuerle, PA; Henkel, T; Pahl, HL; Schmidt, KN; Traenckner, EB; Wilk, S | 1 |
| Liu, F; Roth, RA | 2 |
| Campbell, JS; Dobrowolska, G; Eldar-Finkelman, H; Fischer, EH; Jensen, AM; Krebs, EG; Munar, ES; Reszka, AA; Seger, D; Seger, R | 1 |
| Lewis, RE; Sanderson, SD; Volle, DJ | 1 |
| Eckhart, W; Schönthal, A; Srinivas, S | 1 |
| Feener, EP; Hu, KQ; King, GL; Shiba, T; White, MF; Wilden, PA | 1 |
| Coghlan, MP; Pillay, TS; Siddle, K; Tavaré, JM | 1 |
| Alexander, RW; Griendling, KK; Kai, H; Lassègue, B; Ollerenshaw, JD; Runge, MS | 1 |
| Báez, I; Breithaupt, TB; Eylar, EH; Molina, C; Rivera-Quiñones, C | 1 |
| Capeau, J; Caron, M; Cherqui, G; Picard, J; Reynet, C; Wicek, D | 1 |
| Burn, P; Camoin, L; Fagard, R; Fischer, S; Guillaume, JL; Meggio, F; Rothhut, B; Soula, M; Strosberg, D; Vorherr, T | 1 |
| Comoglio, PM; Gandino, L; Longati, P; Medico, E; Prat, M | 1 |
| Misono, K; Ramchandran, R; Sen, GC; Sen, I | 1 |
| Bonavita, V; Kanfer, JN; Massarelli, R; Singh, IN; Sorrentino, G | 1 |
| Finkenzeller, G; Heidecker, G; Hummel, R; Kochs, G; Kolch, W; Marmé, D; Mischak, H; Rapp, UR; Vahidi, H | 1 |
| Caelles, C; Chojkier, M; Hunter, T; Karin, M; Trautwein, C; van der Geer, P | 1 |
| Decker, SJ; Pang, L; Saltiel, AR | 1 |
| Davis, RJ; Knopf, JL; Lin, AY; Lin, LL; Seth, A; Wartmann, M | 1 |
| Hennekes, H; Nigg, EA; Peter, M; Weber, K | 1 |
| Flint, AJ; Franza, BR; Gebbink, MF; Hill, DE; Tonks, NK | 1 |
| Kim, T; Park, I; Payne, NS; Shin, J; Strominger, JL; Walsh, CT; Winkler, DG | 1 |
| Buczyłko, J; Ohguro, H; Palczewski, K; Rudnicka-Nawrot, M; Taylor, JA; Walsh, KA; Zhao, X | 1 |
| De Nichilo, MO; Yamada, KM | 1 |
| Hasegawa, M; Hidaka, Y; Hirayama, T; Kawano, Y; Kurazono, H; Matsumoto, K; Niidome, T; Padilla, PI; Shimonishi, Y; Wada, A | 1 |
| Herget, T; Palmer, RH; Parker, PJ; Schönwasser, DC | 1 |
| Gysin, S; Imber, R | 2 |
| Anderson, WB; Benvenuto, G; DeClue, JE; Ferrier, AF; Lee, M; Lowy, DR; Morrison, DK | 1 |
| Bjerve, KS; Bleivik, B; White, LR | 1 |
| Downing, JR; Garcia, JV; Luo, T | 1 |
| Bavington, C; Brennan, FR; Glant, TT; Jobanputra, P; Mikecz, K; Morrison, P; Nuki, G; Pinder, S | 1 |
| Lam, V; Mueller, SG; Richmond, A; Schraw, WP; White, JR | 1 |
| Israël, A; Laurent-Winter, C; Weil, R | 1 |
| Altman, A; Elly, C; Lipkowitz, S; Liu, Y; Liu, YC; Yoshida, H | 1 |
| Benna, JE; Dang, PM; Fay, M; Gaudry, M; Gougerot-Pocidalo, MA; Hakim, J; Morel, F | 1 |
| Dorsman, JC; Israël, A; Schouten, GJ; Toebes, M; van der Eb, AJ; Vertegaal, AC; Whiteside, ST; Zantema, A | 1 |
| Gewert, K; Holst, E; Sundler, R; Svensson, U; Wijkander, J | 1 |
| Benito, M; Lorenzo, M; Teruel, T; Valverde, AM | 1 |
| Bottaro, DP; Li, W; Pierce, JH; Zhang, J | 1 |
| Byers, SW; Crockett, C; Jensen, JP; Orford, K; Weissman, AM | 1 |
| Besser, D; El-Shemerly, MY; Nagamine, Y; Nagasawa, M | 1 |
| Castella, P; Caudy, M; Rockwood, J; Ström, A; Wagner, J | 1 |
| De Fea, K; Roth, RA | 1 |
| Fotis, H; Gärtner, EM; Vasilets, LA | 1 |
| Avruch, J; Caudwell, FB; Cohen, P; Dalby, KN; Morrice, N | 1 |
| Asano, M; Asano, T; Kato, K; Morishita, R; Ueda, H | 1 |
| Evans, DL; Jaso-Friedmann, L; Leary, JH | 1 |
| Brown, S; Garcia, DE; Hille, B; Mackie, K | 1 |
| Babior, BM; Benna, JE; Faust, LR; Inanami, O; Johnson, JL; McAdara, JK; Newburger, PE | 1 |
| Joel, PB; Lannigan, DA; Traish, AM | 1 |
| Marksitzer, R; Menoud, PA; Nagamine, Y; Soubt, MK | 1 |
| Barnard, D; Clawson, D; Diaz, B; Marshall, M | 1 |
| Bouin, AP; Fuchs, A; Grandvaux, N; Vignais, PV | 1 |
| Arai, T; Desaki, J; Maeda, N; Matsuda, S; Sakanaka, M; Sudo, S; Tanaka, J; Toku, K | 1 |
| Lau, A; Lin, CS; Lue, TF | 1 |
| Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M | 1 |
| Fujimoto, K; Fukui, H; Kangawa, K; Kikkawa, U; Ogino, S; Ohta, K | 1 |
| Cooper, RG; Marais, R; Marshall, CJ; Mason, CS; Springer, CJ; Superti-Furga, G | 1 |
| Chen, CL; Kerr, LD; Yull, FE | 1 |
| Altman, A; Doyle, M; Elly, C; Giampa, L; Liu, Y; Liu, YC; Meller, N | 1 |
| Andjelković, M; Cron, P; Hemmings, BA; Maira, SM; Parker, PJ | 1 |
| Johansen, B; Moens, U; Seternes, OM | 1 |
| Kuroki, M; O'Flaherty, JT | 1 |
| Chung, C; Han, JM; Kim, JH; Kim, Y; Lee, SD; Lee, TG; Oh, YS; Park, JB; Park, SK; Ryu, SH; Suh, PG; Yoo, JS | 1 |
| Brown, EJ; Wang, J | 1 |
| Carter-Su, C; Herrington, J; Rui, L | 1 |
| Blanchard, JM; Coulon, V; Hipskind, RA; Tourkine, N; Veyrune, JL; Vié, A | 1 |
| Benovic, JL; Marchese, A; Mundell, SJ; Orsini, MJ; Parent, JL | 1 |
| Band, H; Hazeki, K; Hazeki, O; Matsuo, T; Nagasawa, S; Seya, T; Ui, M; Yamashita, T | 1 |
| Ely, BD; Hsieh, JT; Pong, RC; Tseng, CP; Wang, Z; Zhou, J | 1 |
| Boonen, GJ; Mackus, WJ; Medema, RH; Rijksen, G; van Diepen, A; van Oirschot, BA; Verdonck, LF | 1 |
| Comb, MJ; Demeter, MR; Ruan, H; Tan, Y | 1 |
| Adams, JC; Clelland, JD; Collett, GD; Matsumura, F; Yamashiro, S; Zhang, L | 1 |
| Lesslauer, W; Mary, JL; Tomás-Zuber, M | 1 |
| Bossenmaier, B; Häring, HU; Hennige, AM; Kellerer, M; Klein, HH; Krützfeldt, J; Lammers, R; Strack, V | 1 |
| Hirai, H; Launey, T; Matsuda, S; Mikawa, S | 1 |
| Bonventre, JV; Gijón, MA; Leslie, CC; Siddiqi, AR; Spencer, DM | 1 |
| Cohen, P; Lizcano, JM; Morrice, N | 1 |
| Liao, SM; Maniatis, T; Peters, RT | 1 |
| Hunter, T; Potter, LR | 1 |
| Bertorello, AM; Efendiev, R; Féraille, E; Pedemonte, CH; Pressley, TA; Rousselot, M | 1 |
| Chung, HJ; Huganir, RL; Scannevin, RH; Xia, J; Zhang, X | 1 |
| Inaguma, Y; Ito, H; Iwamoto, I; Kamei, K; Kato, K; Nohara, D | 1 |
| Aguilera, J; Gil, C; Najib, A; Pelliccioni, P | 1 |
| Fresno, M; Martin, AG; San-Antonio, B | 1 |
| Davis, WL; Dobransky, T; Rylett, RJ | 1 |
| Beauchemin, N; Fournès, B; Létourneau, S; Sadekova, S; Turbide, C | 1 |
| Benes, C; Soltoff, SP | 1 |
| Liu, JO; Liu, W; Lu, KP; Youn, HD; Zhou, XZ | 1 |
| Kimmich, GA; Manglapus, M; Randles, J; Roussie, J | 1 |
| Abe, K; Higashi, N; Hirai, M; Hirano, T; Miki, T; Mizuno, K; Nakajima, K; Sekimoto, T | 1 |
| Dong, Z; Kaji, A; Ma, W; Miyamoto, K; Nomura, M | 1 |
| Bean, LJ; Chernov, MV; Lerner, N; Stark, GR | 1 |
| Ferranti, P; Franco, P; Malorni, A; Mamone, G; Massa, O; Metafora, S; Metafora, V; Morelli, F; Stiuso, P; Stoppelli, MP | 1 |
| Sakamoto, S; Taniguchi, T | 1 |
| Andreeva, AY; Blasig, IE; Krause, E; Müller, EC; Utepbergenov, DI | 1 |
| Canettieri, G; Mayr, BM; Montminy, MR | 1 |
| Baillie, G; Houslay, MD; MacKenzie, SJ | 1 |
| Kumar, R; Mandal, M; Mazumdar, A; Mishra, SK | 1 |
| Davie, JR; Strelkov, IS | 1 |
| Herbert, TP; Proud, CG; Tee, AR | 1 |
| Fujitani, Y; Gorogawa, S; Hori, M; Kajimoto, Y; Kawamori, D; Kuroda, A; Ohtoshi, K; Umayahara, Y; Yamasaki, Y; Yasuda, T; Yoshida, S | 1 |
| Baudouin, E; Charpenteau, M; Ranjeva, R; Ranty, B | 1 |
| Eason, MG; Liang, M; Liggett, SB; Theiss, CT | 1 |
| Numazaki, M; Tominaga, M; Tominaga, T; Toyooka, H | 1 |
| Boyle, DJ; Saleh, SM; Takemoto, DJ; Wagner, LM | 1 |
| Dhillon, AS; Kolch, W; Mischak, H; Pollock, C; Shaw, PE; Steen, H | 1 |
| Aaronson, D; Catling, AD; Christian, RE; Ficarro, SB; Gioeli, D; Hancock, M; Hunt, DF; Kwiek, JJ; Settlage, RE; Shabanowitz, J; Weber, MJ; White, FM | 1 |
| el-Shemerly, M; Faisal, A; Hess, D; Nagamine, Y | 1 |
| Costa, M; Gonelle-Gispert, C; Halban, P; Sadoul, K; Takahashi, M | 1 |
| Deen, PM; Hofman, E; Markovich, D; Nielsen, S; Savelkoul, PJ; van Balkom, BW; van der Sluijs, P | 1 |
| Han, SW; Henrique-Silva, F; Machado-Santelli, GM; Pfister, SC | 1 |
| Luo, Z; Waelde, CA; Wen, R; Xiang, X; Zang, M | 1 |
| Kang, T; Park, HI; Sang, QX; Suh, Y; Tschesche, H; Zhao, YG | 1 |
| Dallas-Yang, Q; Jiang, G; Liu, F; Moller, DE; Zhang, BB | 1 |
| Barclay, JW; Burgoyne, RD; Ciufo, LF; Craig, TJ; Evans, GJ; Fisher, RJ; Morgan, A | 1 |
| Ho, CS; Joho, RH; Kaczmarek, LK; Macica, CM; von Hehn, CA; Wang, LY; Yokoyama, S | 1 |
| Derynck, R; Fan, H; Turck, CW | 1 |
| Fry, MD; Lampe, PD; Solan, JL; TenBroek, EM | 1 |
| Bertorello, AM; Budu, CE; Cinelli, AR; Efendiev, R; Pedemonte, CH | 1 |
| Brewer, G; Huynh, Y; Lu, J; Sun, Y; Sutphen, K; Wilson, GM | 1 |
| Carpenter, G; Cheng, QC; Tikhomirov, O; Zhou, W | 1 |
| Hedley, D; Midmer, M; Minden, MD; Moore, SJ; Tong, F; Yee, KW; Zanke, BW | 1 |
| DeWeese, TL; Eshleman, JR; Nelson, WG; O'Meally, RN; Parker, AR; Racke, FK; Sahin, F; Su, GH | 1 |
| Auberger, P; Cagnol, S; Colosetti, P; Herrant, M; Jacquel, A; Luciano, F; Pages, G | 1 |
| Biswas, S; Dallas-Yang, Q; Jiang, G; Li, Z; Zhang, BB | 1 |
| Exton, JH; Kam, Y | 1 |
| Chen, JS; Exton, JH | 1 |
| Bae, DS; Bae, YS; Ha, KS; Lee, IH; Rhee, SG; Suh, PG; You, JO | 1 |
| Huang, HC; Nguyen, T; Pickett, CB; Sherratt, PJ | 1 |
| Freund, GG; Godbout, JP; Hartman, ME; Mazzocco, VR; Minor, KD; O'Connor, JC | 1 |
| Blois, JT; Chiles, TC; Mataraza, JM; Mecklenbraüker, I; Tarakhovsky, A | 1 |
| Batra, S; Dillon, I; Huang, W; Mehta, KD; Mishra, V | 1 |
| Ayres, JN; Blumberg, PM; Brodie, C; Garfield, SH; Hur, GM; Hyman, T; Kazimirsky, G; Rubinfeld, H; Steinhart, R; Stone, JC; Toth, A; Yang, D | 1 |
| Brant, K; Chung, D; Galvez, MM; Loch-Caruso, R | 1 |
| Allen-Baume, V; Ball, A; Cockcroft, S; Larijani, B; McDonald, N; Morgan, CP; Morrice, N; Murray-Rust, J; Sapkota, G; Segui, B; Skippen, A | 1 |
| Anjum, R; Ballif, BA; Blenis, J; Gygi, SP; Roux, PP | 1 |
| Boursiquot, JG; Burakoff, SJ; Jin, YJ; Zhang, X | 1 |
| Bird, GS; Hempel, N; Putney, JW; Smyth, JT; Trebak, M; Wedel, BJ | 1 |
| Manno, S; Mohandas, N; Takakuwa, Y | 1 |
| Band, H; Meyer, RD; Rahimi, N; Singh, AJ | 1 |
| Annan, RS; Hall, C; Li, Z; Lim, L; Marler, KJ; McNulty, DE; Sacks, DB | 1 |
| Alexandrov, A; Cartlidge, RA; Cohen, P; Knebel, A; Peggie, M; Phizicky, EM | 1 |
| Arthur, SJ; Dyson, MH; Goto, H; Iborra, FJ; Inagaki, M; Mahadevan, LC; Nightingale, K; Thomson, S | 1 |
| Doctor, RB; Finnigan, C; Fouassier, L; Gidey, E; Housset, C; Howell, KE; McWilliams, RR; Nichols, MT; Robin, H | 1 |
| Burns, KA; Gray, JP; Leas, TL; Perdew, GH; Vanden Heuvel, JP | 1 |
| Bhoumik, A; Habelhah, H; López-Bergami, P; Ronai, Z; Wang, LH; Zhang, W | 1 |
| Alappat, EC; Boyerinas, B; Feig, C; Kidd, VJ; Murmann, AE; Osborn, SL; Peter, ME; Samuels, M; Slaughter, CA; Tang, WJ; Thorburn, A; Volkland, J; Winoto, A | 1 |
| Haneda, M; Li, W; Murakami, K; Nisimoto, Y; Qiao, S; Takeuchi, F; Tsubouchi, R; Yoshino, M | 1 |
| Chattopadhyay, S; Kinter, M; McCue, B; Santhamma, KR; Sen, GC; Sen, I; Sengupta, S | 1 |
| Fiedler, H; Häring, HU; Lehmann, R; Müssig, K; Schleicher, ED; Staiger, H; Weigert, C | 1 |
| Huang, Y; Kwan, HY; Yao, X | 1 |
| Hu, N; Li, L; Sampat, K; Yuspa, SH; Zakari, J | 1 |
| Gerdes, AM; Huber, L; Li, F; Qu, J; Wang, X; Yi, XP; Zhou, J | 1 |
| Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K | 1 |
| Ahlers, BA; Carl, LL; Cheung, JY; Moorman, JR; Mounsey, JP; Rothblum, LI; Song, J; Tucker, AL; Wang, J; Zhang, XQ | 1 |
| Choi, YH; Chua, S; Lee, YK; Moore, DD; Park, YJ | 1 |
| Duronio, V; Vilimek, D | 1 |
| Adachi, S; Iwamoto, R; Mekada, E; Mizushima, H; Ohishi, M; Wang, X | 1 |
| Downes, CP; Gray, A; Jørgensen, CH; Nawaratne, R; Sethi, JK; Siddle, K | 1 |
| Fang, H; Gill, MS; Kamatchi, GL; Patanavanich, S; Rajagopal, S; Sando, JJ; Yi, X | 1 |
| Bode, AM; Cho, YY; Dong, Z; He, Z; Mizuno, H; Seok Choi, H; Tatsumi, Y | 1 |
| Isacke, CM; Thorne, RF; Tzircotis, G | 1 |
| Baroudi, G; Boutjdir, M; Chahine, M; Qu, Y; Ramadan, O | 1 |
| Chilvers, ER; Coadwell, J; Condliffe, AM; Davidson, K; Ellson, CD; Ferguson, GJ; Guillou, H; Hawkins, PT; Stephens, L; Suire, S; Turner, M; Welch, H | 1 |
| Ando, T; Goto, H; Ishiguro, K; Xavier, R | 1 |
| Burgermeister, E; Chuderland, D; Hanoch, T; Liscovitch, M; Meyer, M; Seger, R | 1 |
| Darzynkiewicz, Z; Halicka, HD; Tanaka, T; Traganos, F | 1 |
| Brelivet, Y; Chellappa, K; Maeda, Y; Montana, V; Moras, D; Parpura, V; Paschal, BM; Sladek, FM; Sun, K | 1 |
| Ichiba, H; Kawabata, S; Kimura, S; Moroi, K; Nishiyama, M; Yajima, T | 1 |
| Albertsen, J; Eriksen, HN; Hoffmann, EK; Lambert, IH; Mollerup, J; Wulff, T | 1 |
| Ding, G; Goparaju, SK; Jahangeer, S; Kajimoto, T; Nakamura, SI; Okada, T; Sonoda, H; Yu, H | 1 |
| Chang, YC; Jin, UH; Kang, YJ; Kim, CH | 1 |
| Andriopoulos, N; Geiger, KK; Hoetzel, A; Humar, M; Loop, T; Pahl, HL; Pannen, BH; Roesslein, M; Schmidt, R | 1 |
| Cho, W; Das, S; Gokhale, N; Jung, JW; Kim, JH; Kim, KP; Tian, W; Tun, MP; Wijewickrama, GT | 1 |
| Immenschuh, S; Kietzmann, T; Naidu, S; Wijayanti, N | 1 |
| Gillis, KD; Liu, X; Shu, Y; Takahashi, M; Yang, Y | 1 |
| Castañeda-Patlán, C; García, W; González-Aguilar, H; Lam, TT; Meléndez, L; Mendoza-Hernández, G; Robles-Flores, M | 1 |
| Amargo, EV; Bass-Zubek, AE; Chen, X; Denning, MF; Garcia, NJ; Green, KJ; Hobbs, RP; Hsieh, SN; Wahl, JK | 1 |
| Chandrasekharan, UM; DiCorleto, PE; Kinney, CM; Kinter, M; McDermott, MS; Shen, J; Yang, L | 1 |
| Cao, J; Chen, W; Dai, B; Lin, D; Liu, L; Liu, Y; Ma, D; Sun, Y; Yu, H | 1 |
| Pan, J; Takahashi, A; Yamaguchi, N; Yamasaki, T; Yokoyama, KK | 1 |
| Kim, HS; Lim, IK | 1 |
| Akie, TE; Cantor, AB; Huang, H; Lin, YY; Moran, TB; Steen, H; Tu, N; Waldon, Z; Woo, AJ; Yu, M | 1 |
| Ballim, RD; Mowla, S; Prince, S; Teng, H | 1 |
| Esper, RM; Loeb, JA | 1 |
| Baik, HJ; Huang, Y; Washington, JM; Zuo, Z | 1 |
| Best, AK; Boitano, S; Heberlein, KR; Isakson, BE; Johnstone, SR; Rizzo, MJ; Straub, AC | 1 |
| Al Tanoury, Z; Catillon, M; Friederich, E; Hadzic, E; Halavatyi, A; Hoffmann, C; Moes, M; Schaffner-Reckinger, E; Yatskou, M | 1 |
| Amezcua-Romero, JC; Pantoja, O; Vera-Estrella, R | 1 |
| Dreyer, I; Gambale, F; Sato, A; Uozumi, N | 1 |
| Ali-Osman, F; Okamura, T; Singh, S | 1 |
| Amos, S; Hussaini, IM; Mut, M | 1 |
| Agell, N; Alvarez-Moya, B; Bachs, O; Drosten, M; López-Alcalá, C | 1 |
| Cao, L; Jiang, W; Liu, JO; Pei, Y; Wan, B; Yang, X; Yi, Q; Yu, L; Yu, W; Zhu, P | 1 |
| Boulay, G; Bousquet, SM; Monet, M | 1 |
| Barmack, NH; Qian, Z; Yakhnitsa, V | 1 |
| Caron, E; Hotchin, NA; Lim, J | 1 |
| Baba, M; Kato, K; Kodama, T; Kudo, T; Maruyama, D; Morihara, T; Okochi, M; Sadik, G; Tagami, S; Takeda, M; Tanaka, T; Yanagida, K | 1 |
| Argetsinger, LS; Carter-Su, C; Lanning, NJ; Su, HW | 1 |
| Brooks-Kayal, AR; Farb, DH; Hu, Y; Kim, JH; Lau, GC; Roberts, DS; Russek, SJ | 1 |
| Capmany, A; Colombo, MI; Damiani, MT; Pavarotti, M; Vitale, N | 1 |
| Chang, TW; Deng, YT; Lee, MS; Lin, JK | 1 |
| Kitade, Y; Miyazawa, D; Sato, K; Sugiura-Ogasawara, M; Sugiyama, T; Takahashi, S; Ueda, H; Yamada, K; Yasui, Y | 1 |
| Brautigan, DL; Churchill, ME; Griner, EM; Theodorescu, D | 1 |
| Dong, LQ; Holmes, BM; Hu, D; Langlais, PR; Lee, H; Liu, M; Riojas, RA; Villarreal, R; Wei, L; Yang, X; Zhou, L | 1 |
| Kitade, Y; Miyazawa, D; Sato, K; Ueda, H; Yamada, K; Yasui, Y | 1 |
| Bournier, O; Dang, PM; Debbabi, M; El-Benna, J; Gougerot-Pocidalo, MA; Kroviarski, Y | 1 |
| Arruti, C; Toledo, A; Zolessi, FR | 1 |
| Armbruster, N; Bell, GW; Cermeno, E; Dang, M; Hartmann, M; Herrlich, A; Lauffenburger, DA; Lodish, HF; Miller, MA; Root, DE | 1 |
| D'Aquino, K; Feener, EP; King, GL; Li, Q; Maeda, Y; Mima, A; Mizutani, K; Park, K; Rask-Madsen, C; White, MF; Winnay, J | 1 |
| Boussetta, T; Driss, F; El-Benna, J; Fay, M; Guichardant, M; Lagarde, M; Liu, M; Makni-Maalej, K | 1 |
| Craig, RW; Kasof, G; Nifoussi, SK; Ornstein, DL; Ratcliffe, NR; Strack, S | 1 |
| Lin, L; Shan, H; Wei, J; Yan, R; Zhang, M; Zhang, R; Zhu, YH | 1 |
| Granata, R; Marleau, S; Mulumba, M; Ong, H | 1 |
| Ishihama, Y; Naito, T; Nakayama, K; Shin, HW; Takada, N; Takatsu, H; Takayama, M; Tsumagari, K | 1 |
| Czirják, G; Enyedi, P; Lengyel, M; Pergel, E | 1 |
2 review(s) available for tetradecanoylphorbol acetate and serine
| Article | Year |
|---|---|
Receptor associated phosphorylation following monoclonal antibody or synthetic peptide binding to nonspecific cytotoxic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Cytotoxicity, Immunologic; Genistein; Ictaluridae; Isoquinolines; Killer Cells, Natural; Molecular Sequence Data; Oxazolone; Peptides; Phosphorylation; Phosphoserine; Protein Kinase C; Quinolines; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Role of protein phosphorylation in the regulation of NF-E2-related factor 2 activity.
Topics: Animals; Carrier Proteins; Cell Nucleus; Cytoplasm; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Humans; Isoenzymes; Leucine Zippers; Models, Biological; NF-E2-Related Factor 2; Phosphorylation; Protein Kinase C; Proteins; Serine; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors | 2004 |
251 other study(ies) available for tetradecanoylphorbol acetate and serine
| Article | Year |
|---|---|
Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity.
Topics: Cell Line; Chromatography, Affinity; Glutathione Transferase; Humans; Kinetics; Leukemia; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Phosphatase 2; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Threonine | 1992 |
Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Chromatography, Affinity; Colforsin; Cyclic AMP; Epidermal Growth Factor; Immunoblotting; Kinetics; Molecular Sequence Data; Oncogene Proteins; Organ Specificity; PC12 Cells; Phosphorylation; Precipitin Tests; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Serine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases | 1992 |
Phorbol esters modulate phospholipid metabolism in a human cholinergic cell line, LA-N-2: a possible role for the base exchange enzymes.
Topics: Cells, Cultured; Choline; Ethanolamines; Humans; Lipid Metabolism; Nerve Tissue Proteins; Parasympathetic Nervous System; Phorbol Esters; Phosphatidylserines; Phospholipids; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins | 1992 |
Multisite serine phosphorylation of the insulin and IGF-I receptors in transfected cells.
Topics: Animals; Cell Line; Fibroblasts; Insulin; Insulin-Like Growth Factor I; Peptide Mapping; Phosphorylation; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1991 |
Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II.
Topics: Amino Acid Sequence; Animals; Arsenic; Arsenites; Blotting, Western; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibroblast Growth Factors; Heat-Shock Proteins; HeLa Cells; Humans; Mitogens; Molecular Sequence Data; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Ribosomal Protein S6 Kinases; Serine; Sodium Compounds; Tetradecanoylphorbol Acetate; Thrombin; Trypsin; Tumor Necrosis Factor-alpha | 1992 |
Interleukin 2 stimulates serine phosphorylation of CD45 in CTLL-2.4 cells.
Topics: Animals; Antigens, CD; Antigens, Differentiation; Cells, Cultured; Histocompatibility Antigens; Interleukin-2; Leukocyte Common Antigens; Mice; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Serine; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1991 |
Structural features of the cytoplasmic region of CD4 required for internalization.
Topics: Amino Acid Sequence; CD4 Antigens; Cell Line; Cell Membrane; Endocytosis; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Mutation; Peptide Mapping; Phosphopeptides; Phosphorylation; Serine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Nuclear pp64 is phosphorylated in both serine/threonine and tyrosine through complex pathways regulated by 12-O-tetradecanoylphorbol-13-acetate and platelet-derived growth factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Dimethyl Sulfoxide; Epidermal Growth Factor; Isoquinolines; Kinetics; Nuclear Proteins; Phosphorylation; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1990 |
Protein kinase-c activation inhibits tyrosine phosphorylation of the c-met protein.
Topics: Animals; Diglycerides; Gene Amplification; Gene Expression; Humans; Phorbol Esters; Phosphorylation; Precipitin Tests; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Serine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Role of nuclear protein kinase C in the mitogenic response to platelet-derived growth factor.
Topics: Animals; Bryostatins; Cell Line; Fibroblasts; Lactones; Lamins; Macrolides; Mitogens; Nuclear Envelope; Nuclear Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
12-O-tetradecanoylphorbol-13-acetate stimulates phosphorylation of the 58,000-Mr form of polyomavirus middle T antigen in vivo: implications for a possible role of protein kinase C in middle T function.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Line; Cell Transformation, Viral; Diglycerides; Mice; Molecular Weight; Mutation; Oncogene Proteins, Viral; Phorbols; Phosphorylation; Polyomavirus; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Novel serine phosphorylation of pp60c-src in intact cells after tumor promoter treatment.
Topics: Animals; Carcinogens; Cell Line; Diterpenes; Lung; Mink; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Terpenes; Tetradecanoylphorbol Acetate; Trypsin | 1986 |
Mutation of amino acids in pp60c-src that are phosphorylated by protein kinases C and A.
Topics: Amino Acids; Animals; Cell Transformation, Neoplastic; DNA Mutational Analysis; Gene Expression Regulation; Mice; Mutation; Phosphorylation; Plasmids; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Tetradecanoylphorbol Acetate | 1989 |
Differential regulation of oncogenic and cellular p185 by serine/threonine kinases.
Topics: Cell Division; Cell Line; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Membrane Proteins; Mutation; Oncogene Proteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, ErbB-2; Serine; Tetradecanoylphorbol Acetate; Threonine | 1989 |
Protein kinase C phosphorylates pp60src at a novel site.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Brain; Cells, Cultured; Kinetics; Mice; Muscles; Oncogene Protein pp60(v-src); Phosphorylation; Protein Kinase C; Protein Kinases; Rabbits; Rats; Retroviridae Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1985 |
Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells.
Topics: Animals; Bradykinin; Cell Line; Drug Tolerance; Kinetics; Muscle, Smooth; Norepinephrine; Phosphatidic Acids; Phosphatidylinositols; Phosphorylation; Prazosin; Receptors, Adrenergic, alpha; Serine; Tetradecanoylphorbol Acetate; Threonine | 1987 |
Mitogen treatment of permeabilized human T lymphocytes stimulates rapid tyrosine and serine phosphorylation of a 42 kDa protein.
Topics: Antibodies, Monoclonal; Cell Membrane Permeability; Humans; Mitogens; Phosphoproteins; Phosphorylation; Phytohemagglutinins; Serine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Regulation of insulin receptor internalization in vascular endothelial cells by insulin and phorbol ester.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Endothelium; Insulin; Phosphorylation; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Trypsin; Tyrosine | 1987 |
Regulation of transferrin receptor cycling by protein kinase C is independent of receptor phosphorylation at serine 24 in Swiss 3T3 fibroblasts.
Topics: Animals; Cells, Cultured; Clone Cells; Fibroblasts; Homeostasis; Humans; Kinetics; Mice; Mutation; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Transferrin; Serine; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Chromatography, Affinity; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphoserine; Phosphothreonine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1988 |
Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Enzyme Activation; Humans; Immunosorbent Techniques; Mice; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-abl; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Phorbol ester treatment increases the exocytic rate of the transferrin receptor recycling pathway independent of serine-24 phosphorylation.
Topics: Animals; Cell Line; Exocytosis; Glycine; Humans; Mutation; Phosphorylation; Receptors, Transferrin; Serine; Tetradecanoylphorbol Acetate; Transfection; Transferrin | 1988 |
Phosphorylation of a chromaffin granule-binding protein by protein kinase C.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Annexins; Calcium; Carrier Proteins; Chromaffin Granules; Chromaffin System; Diglycerides; Membrane Proteins; Phosphatidylserines; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine | 1985 |
A tumor promoter stimulates phosphorylation on tyrosine.
Topics: Animals; Chick Embryo; Fibroblasts; Molecular Weight; Phorbols; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1983 |
pp60c-src is a substrate for phosphorylation when cells are stimulated to enter cycle.
Topics: Animals; Blood; Cell Cycle; Chick Embryo; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Oncogene Protein pp60(v-src); Phosphorylation; Platelet-Derived Growth Factor; Serine; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Viral Proteins | 1984 |
PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Baculoviridae; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Peptide Mapping; Phorbol Esters; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Analysis; Serine; Tetradecanoylphorbol Acetate | 1994 |
N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity.
Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Cell Line; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Humans; I-kappa B Proteins; Leupeptins; Lipopolysaccharides; Mice; Molecular Sequence Data; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Deletion; Serine; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Regulated subcellular distribution of the NR1 subunit of the NMDA receptor.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cell Membrane; Exons; Fluorescent Antibody Technique; Microscopy, Confocal; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Quail; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Regulation of human interleukin-8 receptor A: identification of a phosphorylation site involved in modulating receptor functions.
Topics: Alkaloids; Amino Acid Sequence; Animals; Antigens, CD; Binding Sites; DNA, Complementary; Epitopes; Humans; Interleukin-8; Molecular Sequence Data; Mutation; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Receptors, Interleukin; Receptors, Interleukin-8A; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Threonine; Tumor Cells, Cultured; Up-Regulation | 1995 |
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Female; Glutamic Acid; Glutathione; Homocysteine; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Maleates; Mice; Mice, Inbred C57BL; Recombinant Proteins; Salmonella typhi; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
Evidence in support of a role for human T-cell leukemia virus type I Tax in activating NF-kappa B via stimulation of signaling pathways.
Topics: Gene Expression Regulation; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Ionomycin; Leukemia-Lymphoma, Adult T-Cell; Mutagenesis, Site-Directed; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Serine; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Human chorionic gonadotropin (CG)- and phorbol ester-stimulated phosphorylation of the luteinizing hormone/CG receptor maps to serines 635, 639, 649, and 652 in the C-terminal cytoplasmic tail.
Topics: Amino Acid Sequence; Animals; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Down-Regulation; Humans; Inositol Phosphates; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Rats; Receptors, LH; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein.
Topics: Binding Sites; Blood Platelets; Cell Line; Cytoskeleton; GTP-Binding Proteins; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Megakaryocytes; Pertussis Toxin; Phosphorylation; Protein Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Thrombin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Tyrosine; Virulence Factors, Bordetella | 1995 |
Stimulation of receptor protein-tyrosine phosphatase alpha activity and phosphorylation by phorbol ester.
Topics: Cell Line; Humans; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Recombinant Fusion Proteins; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1995 |
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.
Topics: Base Sequence; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligopeptides; Phosphoprotein Phosphatases; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha | 1995 |
Identification of serines-1035/1037 in the kinase domain of the insulin receptor as protein kinase C alpha mediated phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; CHO Cells; Cricetinae; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Protein Kinase C; Receptor, Insulin; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection; Trypsin | 1994 |
Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Biological Transport; Cell Compartmentation; Cell Division; Dose-Response Relationship, Drug; Epidermal Growth Factor; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Protein Conformation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Phorbol ester stimulates phosphorylation on serine 1327 of the human insulin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cells, Cultured; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine | 1994 |
Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity.
Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Chloramphenicol O-Acetyltransferase; Gene Expression; Genes, jun; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; ras Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic; Transfection | 1994 |
Characterization of phorbol ester-stimulated serine phosphorylation of the human insulin receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Cricetinae; Electrophoresis, Polyacrylamide Gel; Epithelium; Humans; Insulin; Kidney; Kinetics; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Rats; Receptor, Insulin; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection; Trypsin | 1994 |
Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation.
Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Cricetinae; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine | 1994 |
Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor.
Topics: Angiotensin II; Animals; Autoradiography; Cells, Cultured; Colforsin; Immunoblotting; Ionomycin; Male; Muscle, Smooth, Vascular; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Anti-CD2-induced tyrosine phosphorylation of T cell polypeptides is independent of the PMA-induced modification of p56lck.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Arsenicals; CD2 Antigens; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitosis; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Immunologic; Serine; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1993 |
Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites.
Topics: Animals; Base Sequence; Cell Membrane; CHO Cells; Cricetinae; Humans; Insulin; Molecular Sequence Data; Oligodeoxyribonucleotides; Phosphorylation; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate | 1994 |
Insulin receptor mutation at tyrosines 1162 and 1163 alters both receptor serine phosphorylation and desensitization.
Topics: Animals; CHO Cells; Cricetinae; Desensitization, Immunologic; Glycogen; Humans; Insulin; Mutation; Phosphorylation; Protein Kinase C; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1994 |
Anti-CD3 and phorbol ester induce distinct phosphorylated sites in the SH2 domain of p56lck.
Topics: Amino Acid Sequence; Binding Sites; CD3 Complex; Cells, Cultured; Indoles; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Maleimides; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Serine; Tetradecanoylphorbol Acetate; Trypsin | 1993 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
Topics: Amino Acid Sequence; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Consensus Sequence; Hepatocyte Growth Factor; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-met; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Serine; Stomach Neoplasms; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Regulated cleavage-secretion of the membrane-bound angiotensin-converting enzyme.
Topics: Amino Acid Sequence; Animals; Arginine; Cell Line; Cell Membrane; Epithelium; Golgi Apparatus; Lysosomes; Male; Mice; Molecular Sequence Data; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Protein Processing, Post-Translational; Rabbits; Serine; Testis; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Possible involvement of the base exchange enzymes in the phospholipid metabolism in LAN-2 cells.
Topics: Choline; Ethanolamine; Ethanolamines; Humans; Neuroblastoma; Phospholipids; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C alpha activates RAF-1 by direct phosphorylation.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Escherichia coli; Mice; Molecular Sequence Data; Moths; Mutation; Peptides; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate | 1993 |
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain.
Topics: Animals; Binding Sites; CCAAT-Enhancer-Binding Proteins; DNA; DNA-Binding Proteins; Fungal Proteins; Gene Expression Regulation; Nuclear Proteins; Phosphopeptides; Phosphorylation; Protein Kinase C; Rats; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1993 |
Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Mice; Phosphorylation; Protein Kinase C; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 1993 |
cPLA2 is phosphorylated and activated by MAP kinase.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Kinetics; Models, Biological; Mutagenesis, Site-Directed; Peptide Mapping; Phospholipases A; Phospholipases A2; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Chickens; HeLa Cells; Humans; Interphase; Lamin Type B; Lamins; Macromolecular Substances; Molecular Sequence Data; Nuclear Proteins; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Sequence Deletion; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation.
Topics: Alanine; Amino Acid Sequence; CDC2 Protein Kinase; Cell Cycle; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Serine; Tetradecanoylphorbol Acetate | 1993 |
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; HeLa Cells; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine | 1993 |
Structural and enzymatic aspects of rhodopsin phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Eye Proteins; G-Protein-Coupled Receptor Kinase 1; Insecta; Isoquinolines; Kinetics; Light; Mass Spectrometry; Mice; Palmitic Acid; Palmitic Acids; Peptide Fragments; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Piperazines; Protein Kinases; Recombinant Proteins; Rhodopsin; Rod Cell Outer Segment; Serine; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Integrin alpha v beta 5-dependent serine phosphorylation of paxillin in cultured human macrophages adherent to vitronectin.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Macrophage Colony-Stimulating Factor; Macrophages; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Vitronectin; Serine; Tetradecanoylphorbol Acetate; Vitronectin | 1996 |
The significance of Ser1029 of the heat-stable enterotoxin receptor (STaR): relation of STa-mediated guanylyl cyclase activation and signaling by phorbol myristate acetate.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Enzyme Activation; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Polymerase Chain Reaction; Protein Kinase C; Receptors, Enterotoxin; Receptors, Guanylate Cyclase-Coupled; Receptors, Peptide; Recombinant Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Signal Transduction; Substrate Specificity; Swine; Tetradecanoylphorbol Acetate | 1996 |
p42 MAPK phosphorylates 80 kDa MARCKS at Ser-113.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogens; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1996 |
Replacement of Ser657 of protein kinase C-alpha by alanine leads to premature down regulation after phorbol-ester-induced translocation to the membrane.
Topics: Alanine; Animals; Binding Sites; Biological Transport, Active; Cattle; Cell Membrane; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Isoenzymes; LLC-PK1 Cells; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Serine; Swine; Tetradecanoylphorbol Acetate | 1996 |
Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.
Topics: 3T3 Cells; Animals; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Mice; Phosphorylation; Point Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Serine; Tetradecanoylphorbol Acetate; Transfection; Zinc | 1997 |
Protein kinase C inhibitors and PAF stimulate phosphatidylserine synthesis in human leucocytes.
Topics: Antineoplastic Agents; Carbon Radioisotopes; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Male; Neutrophils; Phosphatidylserines; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1996 |
Induction of phosphorylation of human immunodeficiency virus type 1 Nef and enhancement of CD4 downregulation by phorbol myristate acetate.
Topics: CD4 Antigens; CD4-Positive T-Lymphocytes; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Gene Products, nef; HIV-1; Humans; Indoles; Isoquinolines; Maleimides; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Recombinant Fusion Proteins; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1997 |
CD44 expression by leucocytes in rheumatoid arthritis and modulation by specific antibody: implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro.
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; Cell Adhesion; Cells, Cultured; Endothelium; Fibroblasts; Flow Cytometry; Granulocytes; Humans; Hyaluronan Receptors; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Metalloendopeptidases; Serine; Synovial Fluid; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor.
Topics: Amino Acid Sequence; Calcium; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Polymerase Chain Reaction; Receptors, Interleukin; Receptors, Interleukin-8B; Serine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1997 |
Regulation of IkappaBbeta degradation. Similarities to and differences from IkappaBalpha.
Topics: Animals; Cell Line; DNA-Binding Proteins; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; I-kappa B Proteins; Lipopolysaccharides; Lysine; Marine Toxins; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motif.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Binding Sites; Carcinogens; COS Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Mice; Molecular Sequence Data; Oncogene Protein v-cbl; Peptide Mapping; Phorbol Esters; Phosphorylation; Protein Conformation; Protein-Tyrosine Kinases; Proteins; Rabbits; Receptor-CD3 Complex, Antigen, T-Cell; Retroviridae Proteins, Oncogenic; Serine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Tyrosine 3-Monooxygenase | 1997 |
Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways.
Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lymphocyte Activation; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate | 1997 |
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Cell Transformation, Viral; COS Cells; DNA-Binding Proteins; Humans; I-kappa B Proteins; Mitogens; Mutation; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Precipitin Tests; Protein Binding; Protein Precursors; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1997 |
Multiple C-terminal serine phosphorylation accompanies both protein kinase C-dependent and -independent activation of cytosolic 85 kDa phospholipase A2 in macrophages.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Female; Fusobacterium nucleatum; Gardnerella vaginalis; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Phosphopeptides; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate | 1997 |
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1997 |
Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Differentiation; DNA, Complementary; Isoenzymes; Mice; Molecular Sequence Data; Monocytes; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Sequence Alignment; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1997 |
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin.
Topics: Amino Acid Sequence; beta Catenin; Consensus Sequence; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Indoles; Maleimides; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Point Mutation; Protein Kinase C; Protein Processing, Post-Translational; Sequence Alignment; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Trans-Activators; Ubiquitins | 1997 |
Phorbol-ester-activated protein kinase C-alpha lacking phosphorylation at Ser657 is down-regulated by a mechanism involving dephosphorylation.
Topics: Animals; Binding Sites; Down-Regulation; Enzyme Activation; Isoenzymes; LLC-PK1 Cells; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Serine; Swine; Tetradecanoylphorbol Acetate | 1997 |
12-O-Tetradecanoylphorbol-13-acetate activates the Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of SOS involving serine phosphorylation of Shc in NIH3T3 cells.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Fibroblast Growth Factor 2; Gene Expression Regulation; Isoenzymes; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-delta; Proteins; ras Proteins; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; SOS Response, Genetics; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1997 |
Mediation of NGF signaling by post-translational inhibition of HES-1, a basic helix-loop-helix repressor of neuronal differentiation.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Differentiation; DNA; Enzyme Inhibitors; Gene Expression; Growth Inhibitors; Helix-Loop-Helix Motifs; Homeodomain Proteins; Indoles; Maleimides; Mice; Nerve Growth Factors; Neurites; Neurons; PC12 Cells; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Rats; Repressor Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor HES-1 | 1997 |
Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Enzyme Activation; Humans; Insulin Receptor Substrate Proteins; Kidney; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
Regulatory phosphorylation of the Na+/K(+)-ATPase from mammalian kidneys and Xenopus oocytes by protein kinases. Characterization of the phosphorylation site for PKC.
Topics: Animals; Brain; Female; Kidney; Kinetics; Mammals; Mutagenesis, Site-Directed; Oocytes; Ouabain; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Xenopus laevis | 1997 |
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Threonine | 1998 |
GTP-binding protein gamma12 subunit phosphorylation by protein kinase C--identification of the phosphorylation site and factors involved in cultured cells and rat tissues in vivo.
Topics: 3T3 Cells; Animals; Antibodies; Binding Sites; GTP-Binding Proteins; Lysophospholipids; Marine Toxins; Mice; Oxazoles; Peptide Fragments; Pertussis Toxin; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Wistar; Serine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Protein kinase C disrupts cannabinoid actions by phosphorylation of the CB1 cannabinoid receptor.
Topics: Analgesics; Animals; Benzoxazines; Calcium Channel Blockers; Calcium Channels; Cannabinoids; Carcinogens; Cells, Cultured; Enzyme Activation; GTP-Binding Proteins; Hormone Antagonists; Indoles; Maleimides; Morpholines; Mutagenesis; Naphthalenes; omega-Conotoxin GVIA; Peptides; Phorbols; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, Cannabinoid; Receptors, Drug; Recombinant Fusion Proteins; Serine; Signal Transduction; Somatostatin; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.
Topics: B-Lymphocytes; Base Sequence; Cells, Cultured; DNA Primers; Enzyme Activation; Humans; Leukocytes; Luminescent Measurements; Mutagenesis, Site-Directed; NADPH Oxidases; Phosphoproteins; Phosphorylation; Phosphoserine; Point Mutation; Recombinant Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Epidermal Growth Factor; Estradiol; Humans; Mammary Glands, Animal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Receptors, Estrogen; Serine; Tetradecanoylphorbol Acetate | 1998 |
Role of tissue-specific transcription factor LFB3 in a cyclic AMP-responsive enhancer of the urokinase-type plasminogen activator gene in LLC-PK1 cells.
Topics: Activating Transcription Factor 1; Animals; Base Sequence; Cell Line, Transformed; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; LLC-PK1 Cells; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Serine; Swine; Tetradecanoylphorbol Acetate; Transcription Factors; Urokinase-Type Plasminogen Activator | 1998 |
Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms.
Topics: Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; Gene Expression Regulation; Guanosine Triphosphate; Molecular Sequence Data; Oncogenes; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
p40(phox) is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase. Implication of a protein kinase c-type kinase in the phosphorylation process.
Topics: Amino Acid Substitution; Animals; Consensus Sequence; Enzyme Activation; HL-60 Cells; Humans; Mutagenesis, Site-Directed; NADPH Oxidases; Neutrophils; Peptide Mapping; Phagocytes; Phosphoproteins; Phosphorylation; Protein Kinase C; Rabbits; Serine; Tetradecanoylphorbol Acetate; Threonine | 1998 |
Neurons induce the activation of microglial cells in vitro.
Topics: Animals; Animals, Newborn; Anions; Astrocytes; Carcinogens; Cell Communication; Cell Culture Techniques; Cell Size; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Glycine; Microglia; Microscopy, Electron; N-Acetylneuraminic Acid; Neuraminidase; Neurons; Rats; Serine; Superoxides; Tetradecanoylphorbol Acetate; Trypsin | 1998 |
Analysis and mapping of plastin phosphorylation.
Topics: Amino Acid Sequence; Base Sequence; Casein Kinase II; Cell Line; DNA Primers; Fibroblasts; Humans; Leukocytes; Membrane Glycoproteins; Microfilament Proteins; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Identification of protein kinase C phosphorylation sites involved in phorbol ester-induced desensitization of the histamine H1 receptor.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Humans; Molecular Sequence Data; Mutation; Peptide Fragments; Phosphorylation; Protein Kinase C; Receptors, Histamine H1; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate | 1999 |
Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation.
Topics: Animals; Cell Membrane; COS Cells; Epidermal Growth Factor; Phosphorylation; Proto-Oncogene Proteins c-raf; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Differential serine phosphorylation regulates IkappaB-alpha inactivation.
Topics: Amino Acid Substitution; Animals; Antigens, CD; Apoptosis; Birds; Cell Line; Conserved Sequence; DNA; DNA-Binding Proteins; Drosophila melanogaster; Genes, Reporter; Humans; I-kappa B Proteins; Jurkat Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Protein kinase C activation inhibits tyrosine phosphorylation of Cbl and its recruitment of Src homology 2 domain-containing proteins.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Enzyme Activation; Humans; Jurkat Cells; Nuclear Proteins; Oncogene Protein v-cbl; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proteins; Retroviridae Proteins, Oncogenic; Serine; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1999 |
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Biological Transport; Cattle; Cell Line; Cell Membrane; Enzyme Activation; Humans; Mitogens; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Time Factors | 1999 |
A dominant role for the Raf-MEK pathway in forskolin, 12-O-tetradecanoyl-phorbol acetate, and platelet-derived growth factor-induced CREB (cAMP-responsive element-binding protein) activation, uncoupled from serine 133 phosphorylation in NIH 3T3 cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dual Specificity Phosphatase 1; Dual Specificity Phosphatase 6; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Immediate-Early Proteins; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 1999 |
Extracellular signal-regulated protein kinase (ERK)-dependent and ERK-independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokines.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Chemotactic Factors; Complement C5a; Cytokines; DNA-Binding Proteins; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Neutrophils; Phosphorylation; Serine; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tyrosine | 1999 |
Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Chromatography, High Pressure Liquid; Enzyme Activation; Fibroblasts; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Mapping; Phospholipase D; Phosphopeptides; Phosphorylation; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine | 1999 |
Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Carbazoles; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Macrophage-1 Antigen; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyrroles; Receptors, IgG; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
SH2-B, a membrane-associated adapter, is phosphorylated on multiple serines/threonines in response to nerve growth factor by kinases within the MEK/ERK cascade.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Membrane; Intracellular Signaling Peptides and Proteins; Mutagenesis, Site-Directed; Nerve Growth Factors; PC12 Cells; Phosphorylation; Rats; Serine; Tetradecanoylphorbol Acetate; Threonine | 1999 |
A novel calcium signaling pathway targets the c-fos intragenic transcriptional pausing site.
Topics: 1-Methyl-3-isobutylxanthine; 5' Untranslated Regions; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Genes, fos; Genes, Reporter; Humans; Introns; L Cells; Metallothionein; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serine; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arrestins; Cell Line; Cell Membrane; Chemokine CCL5; Chemokine CXCL12; Chemokines, CXC; COS Cells; Dynamin I; Dynamins; Endocytosis; GTP Phosphohydrolases; HIV; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, CCR5; Receptors, CXCR4; Recombinant Proteins; Sequence Alignment; Serine; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Role of Syk in Fc gamma receptor-coupled tyrosine phosphorylation of Cbl in a manner susceptible to inhibition by protein kinase C.
Topics: Animals; Enzyme Precursors; Guinea Pigs; Intracellular Signaling Peptides and Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor Protein-Tyrosine Kinases; Receptors, IgG; Serine; Syk Kinase; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases | 1999 |
The role of DOC-2/DAB2 protein phosphorylation in the inhibition of AP-1 activity. An underlying mechanism of its tumor-suppressive function in prostate cancer.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; COS Cells; Genes, Tumor Suppressor; Humans; Male; Molecular Sequence Data; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Proteins; Serine; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Suppressor Proteins | 1999 |
Cyclin D3 regulates proliferation and apoptosis of leukemic T cell lines.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Division; Cyclin D3; Cyclins; Down-Regulation; Electroporation; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Kinetics; Phosphorylation; Receptors, Antigen, T-Cell; Retinoblastoma Protein; Serine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Bryostatins; Carrier Proteins; Cell Line; COS Cells; Enzyme Activators; Enzyme Inhibitors; Humans; Lactones; Macrolides; Phosphorylation; Protein Isoforms; Protein Kinase C; Recombinant Fusion Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 1999 |
Cell-matrix adhesions differentially regulate fascin phosphorylation.
Topics: Actins; Animals; Carrier Proteins; Cell Adhesion; Cells, Cultured; Cytoskeleton; Extracellular Matrix; Fibronectins; Fluorescent Antibody Technique; Isoenzymes; Laminin; Mice; Microfilament Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Serine; Swine; Tetradecanoylphorbol Acetate; Thrombospondin 1 | 1999 |
Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor.
Topics: Amino Acid Sequence; Catalytic Domain; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; HeLa Cells; Humans; Indoles; Insulin; Ionomycin; Isoquinolines; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Ribosomal Protein S6 Kinases; Serine; Signal Transduction; Substrate Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha | 2000 |
Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta.
Topics: Adenosine Triphosphate; Alanine; Cell Line; Humans; Insulin Resistance; Isoenzymes; Phosphorylation; Point Mutation; Protein Kinase C; Receptor, Insulin; Serine; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons.
Topics: Animals; Biological Transport; Cells, Cultured; Dendrites; Electrophysiology; Enzyme Activation; Hand Strength; Models, Neurological; Neuronal Plasticity; Neurons; Phosphorylation; Protein Kinase C; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Serine; Synapses; Tetradecanoylphorbol Acetate | 2000 |
Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation.
Topics: Animals; Anisomycin; Arachidonic Acid; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NADPH Oxidases; Okadaic Acid; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Synthesis Inhibitors; Serine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2000 |
Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155.
Topics: 14-3-3 Proteins; Animals; Antibodies; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cells, Cultured; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Humans; Insulin-Like Growth Factor I; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2000 |
IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex.
Topics: Amino Acid Sequence; Enzyme Induction; HeLa Cells; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Jurkat Cells; Molecular Sequence Data; Phosphorylation; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Binding; Protein Conformation; Protein Serine-Threonine Kinases; Receptors, Antigen, T-Cell; Sequence Homology, Amino Acid; Serine; Signal Transduction; Small-Conductance Calcium-Activated Potassium Channels; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
Activation of protein kinase C stimulates the dephosphorylation of natriuretic peptide receptor-B at a single serine residue: a possible mechanism of heterologous desensitization.
Topics: Alanine; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Cyclic GMP; Detergents; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Ligands; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Receptors, Atrial Natriuretic Factor; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Simultaneous phosphorylation of Ser11 and Ser18 in the alpha-subunit promotes the recruitment of Na(+),K(+)-ATPase molecules to the plasma membrane.
Topics: 2,4-Dinitrophenol; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Biological Transport; Cell Membrane; Colchicine; Enzyme Activation; Isoenzymes; Membrane Proteins; Phosphorylation; Potassium Cyanide; Protein Kinase C; Protein Kinase C beta; Rodentia; Rubidium; Serine; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 2000 |
Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins.
Topics: Animals; Carrier Proteins; Cells, Cultured; Cytoskeletal Proteins; Humans; Kidney; Ligands; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Nuclear Proteins; Nuclear Receptor Coactivator 2; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, AMPA; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Two-Hybrid System Techniques | 2000 |
Phosphorylation-induced change of the oligomerization state of alpha B-crystallin.
Topics: Animals; CHO Cells; Circular Dichroism; COS Cells; Cricetinae; Crystallins; Hot Temperature; Humans; Luciferases; Molecular Chaperones; Molecular Weight; Mutagenesis, Site-Directed; Phosphorylation; Protein Folding; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Serotonin transporter phosphorylation modulated by tetanus toxin.
Topics: Animals; Biological Transport; Brain; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Isotope Labeling; Maleimides; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Serine; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tetanus Toxin; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases; Tyrosine | 2000 |
Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha.
Topics: Amino Acid Sequence; Amino Acid Substitution; Humans; Ionomycin; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-rel; Recombinant Proteins; Sequence Deletion; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2001 |
Functional characterization of phosphorylation of 69-kDa human choline acetyltransferase at serine 440 by protein kinase C.
Topics: Acetylcholine; Amino Acid Sequence; Base Sequence; Catalysis; Cell Line; Choline O-Acetyltransferase; DNA Primers; Enzyme Activation; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2001 |
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoembryonic Antigen; Carcinogenicity Tests; Carcinoma; Cell Adhesion Molecules; Colonic Neoplasms; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Naphthalenes; Point Mutation; Protein Kinase C; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis-trans isomerase Pin1.
Topics: Amino Acid Motifs; Blotting, Western; Calcineurin; Calcium; cis-trans-Isomerases; DNA-Binding Proteins; Doxycycline; Glutathione Transferase; Humans; Ionomycin; Jurkat Cells; Lymphocyte Activation; NFATC Transcription Factors; NIMA-Interacting Peptidylprolyl Isomerase; Nuclear Proteins; Peptidylprolyl Isomerase; Phosphorylation; Plasmids; Proline; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 2001 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Antigens, CD; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Cytokine Receptor gp130; DNA Primers; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Granulocyte Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-6; Liver Neoplasms; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.
Topics: Animals; Apoptosis; Blotting, Western; Boron Compounds; Caffeic Acids; Carcinogens; Caspase 3; Caspases; Cell Division; Cell Line; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Methacrylates; Methylmethacrylates; Mice; Phenylethyl Alcohol; Phosphorylation; Precipitin Tests; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53 | 2001 |
Regulation of ubiquitination and degradation of p53 in unstressed cells through C-terminal phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrolysis; Mice; Nuclear Proteins; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Serine; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ubiquitins | 2001 |
Phosphorylation of seminal vesicle protein IV on Ser58 enhances its peroxidase-stimulating activity.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cyclic AMP-Dependent Protein Kinases; Glutathione Peroxidase; Horseradish Peroxidase; Kinetics; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Inbred F344; Rats, Wistar; Seminal Plasma Proteins; Seminal Vesicles; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate | 2001 |
Identification of a phorbol ester-responsive element in the interferon-gamma receptor 1 chain gene.
Topics: Base Sequence; Carcinogens; Cells, Cultured; DNA; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon gamma Receptor; Interferon-gamma; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Promoter Regions, Genetic; Receptors, Interferon; Serine; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 2001 |
Protein kinase C regulates the phosphorylation and cellular localization of occludin.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Calcium; Carcinogens; Cell Line; Cells, Cultured; Cytoplasm; Detergents; Diglycerides; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; Membrane Proteins; Mice; Microscopy, Fluorescence; Occludin; Octoxynol; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors | 2001 |
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.
Topics: Animals; Cell Line; CREB-Binding Protein; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Humans; Mitogens; Nuclear Proteins; PC12 Cells; Phosphorylation; Rats; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Activation | 2001 |
Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cells, Cultured; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Activation; Humans; Indomethacin; Isoenzymes; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Serine; Tetradecanoylphorbol Acetate | 2001 |
Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells.
Topics: Acetylation; Base Sequence; Breast Neoplasms; Chromatin; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Ser-10 phosphorylation of histone H3 and immediate early gene expression in oncogene-transformed mouse fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Transformation, Neoplastic; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Histones; MAP Kinase Signaling System; Mice; Phosphorylation; ras Proteins; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 2002 |
The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites.
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Cycle Proteins; Cell Line; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Protein kinase C-dependent, CCAAT/enhancer-binding protein beta-mediated expression of insulin-like growth factor I gene.
Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Insulin-Like Growth Factor I; Maleimides; Promoter Regions, Genetic; Protein Kinase C; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA, Messenger; Serine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
A 45-kDa protein kinase related to mitogen-activated protein kinase is activated in tobacco cells treated with a phorbol ester.
Topics: Cells, Cultured; Cycloheximide; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Weight; Nicotiana; Phosphorylation; Plant Proteins; Serine; Stress, Mechanical; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2002 |
Phosphorylation of Ser360 in the third intracellular loop of the alpha2A-adrenoceptor during protein kinase C-mediated desensitization.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Genotype; Humans; Inositol 1,4,5-Trisphosphate; Mutation; Phosphorylation; Radioligand Assay; Receptors, Adrenergic, alpha-2; Serine; Tetradecanoylphorbol Acetate | 2002 |
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residues.
Topics: Adenosine Triphosphate; Carcinogens; Cell Line; Cytoplasm; Electrophysiology; Glutathione Transferase; Humans; Isoenzymes; Models, Biological; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Isoforms; Protein Kinase C; Protein Kinase C-epsilon; Protein Structure, Tertiary; Receptors, Drug; Recombinant Fusion Proteins; Serine; Temperature; Tetradecanoylphorbol Acetate | 2002 |
Effect of protein kinase Cgamma on gap junction disassembly in lens epithelial cells and retinal cells in culture.
Topics: Animals; Connexin 43; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epithelial Cells; Gap Junctions; Genetic Vectors; Humans; Isoenzymes; Lens, Crystalline; Microscopy, Confocal; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C-alpha; Rabbits; Retinal Neoplasms; Retinoblastoma; Serine; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2002 |
Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Genes, Reporter; Mice; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-raf; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Affinity; Colforsin; COS Cells; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Ligands; Male; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphopeptides; Phosphorylation; Plasmids; Prostatic Neoplasms; Protein Kinase C; Receptors, Androgen; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 2002 |
Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Insulin; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Proteins; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion.
Topics: Animals; Botulinum Toxins; Calcium; Carbachol; Enzyme Activation; Exocytosis; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Kinetics; Membrane Proteins; Mutation; Nerve Tissue Proteins; PC12 Cells; Phosphorylation; Protein Kinase C; Rats; Serine; SNARE Proteins; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 2002 |
The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel.
Topics: Amino Acid Sequence; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Cell Line; Cell Membrane; Colforsin; Dogs; Endocytosis; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Protein Transport; Serine; Tetradecanoylphorbol Acetate | 2002 |
Mutational analyses of the signals involved in the subcellular location of DSCR1.
Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Enzyme Activation; Epitopes; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Autolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activity.
Topics: ADAM Proteins; Animals; Base Sequence; Cell Line; Cysteine; Disintegrins; DNA Primers; Glutamic Acid; Humans; Hydrolysis; Kinetics; Membrane Proteins; Metalloendopeptidases; Metalloproteases; Muscle Proteins; Mutagenesis; Protein Processing, Post-Translational; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate | 2002 |
Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells.
Topics: Animals; Anthracenes; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Insulin Receptor Substrate Proteins; Insulin Resistance; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kidney; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Salicylic Acid; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Phosphorylation of Munc18 by protein kinase C regulates the kinetics of exocytosis.
Topics: Animals; Calcium; Cattle; Exocytosis; HeLa Cells; Humans; Kinetics; Membrane Proteins; Munc18 Proteins; Nerve Tissue Proteins; Phosphorylation; Protein Kinase C; Proteins; Qa-SNARE Proteins; Rabbits; Serine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 2003 |
Modulation of the kv3.1b potassium channel isoform adjusts the fidelity of the firing pattern of auditory neurons.
Topics: Action Potentials; Animals; Brain Stem; Cells, Cultured; CHO Cells; Cricetinae; Electric Conductivity; Evoked Potentials, Auditory; Kinetics; Mice; Mice, Knockout; Neurons; Neuropeptides; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Isoforms; Protein Kinase C; Serine; Shaw Potassium Channels; Tetradecanoylphorbol Acetate | 2003 |
Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; CHO Cells; Cricetinae; Cytoplasm; Genetic Vectors; HeLa Cells; Humans; MAP Kinase Signaling System; Metalloendopeptidases; Molecular Sequence Data; Peptides; Phosphoamino Acids; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha; Trypsin | 2003 |
Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation.
Topics: Animals; Antibody Specificity; Carcinogens; Cell Membrane; Cells, Cultured; Connexin 43; Cytoplasm; Enzyme Activation; G2 Phase; Gap Junctions; Kidney; Mitosis; Phosphorylation; Protein Kinase C; Rats; S Phase; Serine; Tetradecanoylphorbol Acetate | 2003 |
Intracellular Na+ regulates dopamine and angiotensin II receptors availability at the plasma membrane and their cellular responses in renal epithelia.
Topics: Absorption; Angiotensin II; Animals; Cell Line; Cell Membrane; Dopamine; Epithelial Cells; Homeostasis; Kidney; Kidney Tubules, Proximal; Opossums; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Dopamine D1; Rubidium; Serine; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Western; Cell Adhesion; Cell Line; Cytoplasm; Dactinomycin; Heterogeneous Nuclear Ribonucleoprotein D0; Heterogeneous-Nuclear Ribonucleoprotein D; Humans; Interleukin-1; Kinetics; Leukemia; Mass Spectrometry; Molecular Sequence Data; Monocytes; Peptides; Phosphorylation; Polyribosomes; Protein Binding; Protein Processing, Post-Translational; Ribonucleases; RNA, Messenger; Sequence Homology, Amino Acid; Serine; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Ectodomain cleavage of ErbB-4: characterization of the cleavage site and m80 fragment.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Detergents; ErbB Receptors; Humans; Metalloendopeptidases; Mice; Molecular Sequence Data; Peptides; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptor, ErbB-4; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
NKIAMRE, a novel conserved CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Base Sequence; Blotting, Northern; Blotting, Western; Brain; CDC2 Protein Kinase; Chromosomes, Human, Pair 5; Cloning, Molecular; COS Cells; Cytoplasm; DNA, Complementary; Exons; Gene Library; Genetic Vectors; Humans; Lysine; MAP Kinase Signaling System; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myelin Basic Protein; Myocardium; Open Reading Frames; Phosphorylation; Phylogeny; Precipitin Tests; Protein Isoforms; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Tissue Distribution; Transfection; Tumor Cells, Cultured | 2003 |
Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles.
Topics: Adenine; Adjuvants, Immunologic; Alleles; Amino Acid Sequence; Base Pair Mismatch; Carcinogens; Casein Kinase II; Cell Line, Tumor; Chromatography, Liquid; Colorectal Neoplasms; Cyclic AMP-Dependent Protein Kinases; Cytosine; DNA Damage; DNA Glycosylases; DNA Repair; Guanosine; Humans; Immunoblotting; Indoles; Maleimides; Microsatellite Repeats; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; Serine; Software; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.
Topics: Amino Acid Sequence; Antineoplastic Agents, Hormonal; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Binding Sites; Carrier Proteins; Caspases; Cell Line; Cell Survival; Cysteine Endopeptidases; Gene Expression Regulation; Glutathione Transferase; Humans; K562 Cells; Lymphoma; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Isoforms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Serine; Tamoxifen; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
Rosiglitazone, an agonist of peroxisome-proliferator-activated receptor gamma (PPARgamma), decreases inhibitory serine phosphorylation of IRS1 in vitro and in vivo.
Topics: Adipocytes; Adipose Tissue; Animals; Cell Line; Drug Synergism; Fatty Acids; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Serine; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transcription Factors | 2004 |
Role of phospholipase D in the activation of protein kinase D by lysophosphatidic acid.
Topics: 1-Butanol; Animals; Blotting, Western; Cells, Cultured; Clone Cells; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Lysophospholipids; Phosphatidic Acids; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate | 2004 |
Regulation of phospholipase D2 activity by protein kinase C alpha.
Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Indoles; Maleimides; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection | 2004 |
AHNAK-mediated activation of phospholipase C-gamma1 through protein kinase C.
Topics: Animals; Arachidonic Acid; Blotting, Western; Bradykinin; Calcium; COS Cells; Enzyme Activation; Gene Library; Glutathione Transferase; Humans; Inositol Phosphates; Isoenzymes; Membrane Proteins; Mice; Microscopy, Fluorescence; Models, Biological; Neoplasm Proteins; NIH 3T3 Cells; Phospholipase C beta; Phospholipase C gamma; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Type C Phospholipases; Tyrosine | 2004 |
Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
Topics: Amino Acid Motifs; Animals; Blood Glucose; Blotting, Western; Cell Line; Diabetes Mellitus, Type 2; Glucose; Heterozygote; Humans; Insulin; Insulin Receptor Substrate Proteins; Interleukin-4; Intracellular Signaling Peptides and Proteins; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Serine; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2004 |
B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta.
Topics: Acetamides; Acetophenones; Animals; B-Lymphocytes; Benzopyrans; Binding Sites; Blotting, Western; Bryostatins; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Division; Cross-Linking Reagents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Lactones; Macrolides; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mitogens; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Pyrans; Receptors, Antigen, B-Cell; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Spiro Compounds; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner.
Topics: Histones; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phorbol Esters; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Receptors, LDL; Serine; Tetradecanoylphorbol Acetate | 2004 |
PKCdelta associates with and is involved in the phosphorylation of RasGRP3 in response to phorbol esters.
Topics: Animals; Biological Transport; CHO Cells; Cricetinae; Electrophoresis; Female; Guanine Nucleotide Exchange Factors; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; ras Guanine Nucleotide Exchange Factors; Serine; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Cell and toxicant specific phosphorylation of conexin43: effects of lindane and TPA on rat myometrial and WB-F344 liver cell gap junctions.
Topics: Animals; Blotting, Western; Cell Line; Cells, Cultured; Connexin 43; Female; Fluorescent Dyes; Gap Junctions; Hexachlorocyclohexane; Isoquinolines; Liver; Microscopy, Fluorescence; Myometrium; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Serine; Tetradecanoylphorbol Acetate | 2004 |
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
Topics: Animals; Binding Sites; Brain; Cell Membrane; Chromatography; Chromatography, High Pressure Liquid; COS Cells; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; HeLa Cells; HL-60 Cells; Humans; Isoelectric Focusing; Lipid Metabolism; Microscopy, Confocal; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phospholipid Transfer Proteins; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection; Type C Phospholipases | 2004 |
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
Topics: Amino Acid Sequence; Animals; Cell Line; Enzyme Activation; Humans; MAP Kinase Signaling System; Models, Biological; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Repressor Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2004 |
CD4 phosphorylation partially reverses Nef down-regulation of CD4.
Topics: CD4 Antigens; Cell Fractionation; Cell Membrane; Clone Cells; Cross-Linking Reagents; Down-Regulation; Drug Synergism; Gene Products, nef; HIV; Humans; Jurkat Cells; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Serine; Staining and Labeling; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 2004 |
Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712.
Topics: Amino Acid Sequence; Cell Line; Dose-Response Relationship, Drug; Humans; Ion Channels; Molecular Sequence Data; Phosphorylation; Point Mutation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; TRPC Cation Channels | 2005 |
Modulation of erythrocyte membrane mechanical function by protein 4.1 phosphorylation.
Topics: Actins; Binding Sites; Blood Proteins; Calmodulin-Binding Proteins; Casein Kinase I; Cell Membrane; Cytoskeletal Proteins; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocyte Membrane; Erythrocytes; Humans; Immunoblotting; Membrane Proteins; Microtubule-Associated Proteins; Models, Biological; Phosphorylation; Protein Binding; Protein Kinase C; Protein Processing, Post-Translational; Protein Structure, Tertiary; Serine; Sodium Dodecyl Sulfate; Spectrin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
The carboxyl terminus of VEGFR-2 is required for PKC-mediated down-regulation.
Topics: Animals; Cell Line; Down-Regulation; Enzyme Activation; ErbB Receptors; Humans; Ligands; Phospholipase C gamma; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Serine; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases; Ubiquitin-Protein Ligases; Vascular Endothelial Growth Factor Receptor-2 | 2005 |
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner.
Topics: Amino Acid Sequence; Animals; Breast Neoplasms; Cell Line, Tumor; Epithelial Cells; Female; Humans; Indoles; Isoenzymes; Maleimides; Molecular Sequence Data; Neurites; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; ras GTPase-Activating Proteins; Rats; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate | 2005 |
The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.
Topics: Amino Acid Sequence; Animals; GTP-Binding Proteins; HeLa Cells; Humans; Insulin-Like Growth Factor I; Methyltransferases; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; RNA, Transfer; Serine; Tetradecanoylphorbol Acetate; tRNA Methyltransferases | 2005 |
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.
Topics: Acetylation; Animals; Anisomycin; Cell Line; Cell Nucleus; Chromatin; Epidermal Growth Factor; Histones; Hydroxamic Acids; Interphase; Mice; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 8; Phosphorylation; Serine; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Protein kinase C regulates the phosphorylation and oligomerization of ERM binding phosphoprotein 50.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cell Line; Culture Media, Serum-Free; Humans; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Rats; Recombinant Fusion Proteins; Serine; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2005 |
Regulation of peroxisome proliferator-activated receptor alpha by protein kinase C.
Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; Consensus Sequence; COS Cells; Humans; Mice; Mice, Knockout; Mutagenesis, Site-Directed; Phosphorylation; PPAR alpha; Protein Kinase C; Pyrimidines; Rats; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2005 |
RACK1 mediates activation of JNK by protein kinase C [corrected].
Topics: Animals; Anisomycin; Antibodies, Phospho-Specific; Apoptosis; Binding Sites; Carbazoles; Catalysis; Cell Line; Cell Line, Tumor; Cytoplasm; Enzyme Inhibitors; Gene Deletion; GTP-Binding Proteins; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase 7; MAP Kinase Kinase Kinase 1; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Models, Biological; Neoplasm Proteins; Phosphopeptides; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C beta; Receptors for Activated C Kinase; Receptors, Cell Surface; RNA, Small Interfering; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2005 |
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Casein Kinase Ialpha; Cell Cycle; Cell Line; Cell Nucleus; Concanavalin A; Cytosol; Enzyme Inhibitors; Fas-Associated Death Domain Protein; HeLa Cells; Humans; Isoquinolines; Jurkat Cells; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitosis; Molecular Sequence Data; Mutation; Paclitaxel; Phosphorylation; Protein Binding; Protein Transport; RNA, Small Interfering; Sequence Homology, Amino Acid; Serine; Spindle Apparatus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Rosmarinic acid inhibits the formation of reactive oxygen and nitrogen species in RAW264.7 macrophages.
Topics: Animals; Antioxidants; Cell Line; Cell Survival; Cinnamates; Depsides; Dose-Response Relationship, Drug; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phosphorylation; Reactive Nitrogen Species; Reactive Oxygen Species; Rosmarinic Acid; Serine; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2005 |
Calmodulin binds to the cytoplasmic domain of angiotensin-converting enzyme and regulates its phosphorylation and cleavage secretion.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell Line; Cytoplasm; DNA Mutational Analysis; Epithelial Cells; Mass Spectrometry; Membrane Proteins; Mice; Peptidyl-Dipeptidase A; Phosphorylation; Serine; Tetradecanoylphorbol Acetate | 2005 |
Insulin-induced stimulation of JNK and the PI 3-kinase/mTOR pathway leads to phosphorylation of serine 318 of IRS-1 in C2C12 myotubes.
Topics: Animals; Cell Line; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Serine; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2005 |
Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G.
Topics: Animals; Calcium Signaling; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diglycerides; Endothelial Cells; Humans; Microfilament Proteins; Models, Biological; Mutation; Nitric Oxide Donors; Penicillamine; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Serine; Tetradecanoylphorbol Acetate; Transfection; TRPC Cation Channels | 2006 |
Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes.
Topics: Adenoviridae; Animals; Apoptosis; Cells, Cultured; Immunoblotting; Immunoprecipitation; Indoles; Insulin-Like Growth Factor I; Keratinocytes; Maleimides; Mice; Phosphoprotein Phosphatases; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Phosphatase 2; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays | 2006 |
Nuclear compartmentalization of FAK and FRNK in cardiac myocytes.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Cell Nucleus; Cell Separation; Chromosomal Proteins, Non-Histone; DNA-Binding Proteins; Female; Fluorescent Antibody Technique; Focal Adhesion Protein-Tyrosine Kinases; Heart Failure; Immunoprecipitation; Microscopy, Confocal; Myocytes, Cardiac; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA-Binding Proteins; Serine; Tetradecanoylphorbol Acetate | 2006 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.
Topics: Adenosine Triphosphatases; Alanine; Animals; Calsequestrin; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Immunoblotting; Ions; Membrane Proteins; Mice; Mice, Knockout; Muscle Cells; Muscles; Mutation; Myocardium; Phosphoproteins; Phosphorylation; Serine; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Phosphorylation of the hinge domain of the nuclear hormone receptor LRH-1 stimulates transactivation.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Butadienes; Cell Line; Cell Nucleus; Cholesterol 7-alpha-Hydroxylase; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; HeLa Cells; Humans; Ligands; MAP Kinase Signaling System; Mitogens; Molecular Sequence Data; Mutation; Nitriles; Phosphoproteins; Phosphorylation; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Cytoplasmic and Nuclear; RNA Splicing Factors; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 2006 |
Cytokine-stimulated phosphorylation of GSK-3 is primarily dependent upon PKCs, not PKB.
Topics: Animals; Cells, Cultured; Culture Media, Conditioned; Cytokines; Diglycerides; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Humans; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Tetradecanoylphorbol Acetate | 2006 |
Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.
Topics: Alanine; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chlorocebus aethiops; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ionophores; Lysophospholipids; Male; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Serine; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vero Cells | 2006 |
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.
Topics: 3T3-L1 Cells; Animals; Blood Proteins; Catalytic Domain; Ceramides; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Models, Molecular; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Structure, Tertiary; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Inhibitory role of Ser-425 of the alpha1 2.2 subunit in the enhancement of Cav 2.2 currents by phorbol-12-myristate, 13-acetate.
Topics: Alternative Splicing; Amino Acid Substitution; Animals; Calcium Channels, N-Type; DNA, Complementary; Female; Genetic Variation; Kinetics; Methacholine Chloride; Oocytes; Phosphorylation; Protein Kinase C; Protein Subunits; Rats; Recombinant Proteins; Serine; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Xenopus laevis | 2006 |
Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
Topics: Animals; Base Sequence; Cell Growth Processes; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Epidermal Growth Factor; MAP Kinase Kinase 4; Mice; Molecular Sequence Data; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Serine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Directional sensing of a phorbol ester gradient requires CD44 and is regulated by CD44 phosphorylation.
Topics: Amino Acid Sequence; Cell Line, Tumor; Chemotaxis; Cyclic AMP-Dependent Protein Kinases; Humans; Hyaluronan Receptors; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Protein kinase C activation inhibits Cav1.3 calcium channel at NH2-terminal serine 81 phosphorylation site.
Topics: Amino Acid Sequence; Animals; Calcium Channels; Calcium Channels, L-Type; Cell Line; Enzyme Activation; Humans; Isoenzymes; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils.
Topics: Animals; Binding Sites; Blotting, Western; Cell Movement; Class I Phosphatidylinositol 3-Kinases; Complement C5a; Dose-Response Relationship, Drug; Female; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; ras Proteins; Reactive Oxygen Species; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Bcl10 is phosphorylated on Ser138 by Ca2+/calmodulin-dependent protein kinase II.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; B-Cell CLL-Lymphoma 10 Protein; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; CARD Signaling Adaptor Proteins; Caspases; Guanylate Cyclase; Humans; Ionomycin; Ionophores; Isoenzymes; Jurkat Cells; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Mutation, Missense; Neoplasm Proteins; NF-kappa B; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Receptors, Antigen, T-Cell; RNA, Small Interfering; Serine; Signal Transduction; Sulfonamides; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2007 |
Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma.
Topics: Active Transport, Cell Nucleus; Acyl-CoA Oxidase; Animals; Cell Nucleus; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Cytosol; Down-Regulation; HeLa Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 3; PPAR gamma; Protein Binding; Protein Structure, Tertiary; Protein Transport; Rats; Rosiglitazone; Serine; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transcriptional Activation; Two-Hybrid System Techniques | 2007 |
Phosphorylation of histone H2AX on Ser 139 and activation of ATM during oxidative burst in phorbol ester-treated human leukocytes.
Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Damage; DNA-Binding Proteins; Fluorescent Antibody Technique; Histones; Humans; Leukocytes; Phosphorylation; Protein Serine-Threonine Kinases; Respiratory Burst; Serine; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2006 |
Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Nucleus; Conserved Sequence; Cytoplasm; DNA; Down-Regulation; Hepatocyte Nuclear Factor 4; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Rats; Receptors, Cytoplasmic and Nuclear; Serine; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2007 |
Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function.
Topics: Calcium; Cell Line; Electrophoresis, Polyacrylamide Gel; Endothelin-1; GTP-Binding Protein alpha Subunits; Humans; Peptide Fragments; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RGS Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Homologous desensitisation of the mouse leukotriene B4 receptor involves protein kinase C-mediated phosphorylation of serine 127.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Amino Acid Sequence; Animals; Enzyme Activation; Fatty Alcohols; Female; Glycols; In Vitro Techniques; Leukotriene B4; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Pertussis Toxin; Phosphorylation; Protein Kinase C; Receptors, Leukotriene B4; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Triterpenes | 2007 |
Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 2.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; HeLa Cells; Humans; Nuclear Export Signals; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Serine; Tetradecanoylphorbol Acetate | 2007 |
Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells.
Topics: Adaptor Proteins, Signal Transducing; Apolipoprotein B-100; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Hepatocytes; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; JNK Mitogen-Activated Protein Kinases; Lipoproteins, VLDL; Metabolic Syndrome; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Risk Factors; Serine; Tetradecanoylphorbol Acetate; Vanadates | 2008 |
The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun.
Topics: Animals; Antibodies; CD28 Antigens; CD3 Complex; Cell Line; Cell Line, Tumor; Dactinomycin; DNA; Enzyme Inhibitors; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Serine; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Mechanism of regulation of group IVA phospholipase A2 activity by Ser727 phosphorylation.
Topics: Animals; Cell Line; Genetic Vectors; Humans; Ionomycin; Phospholipases A2; Phosphorylation; Serine; Spodoptera; Surface Plasmon Resonance; Tetradecanoylphorbol Acetate | 2008 |
Inhibition of phorbol ester-dependent peroxiredoxin I gene activation by lipopolysaccharide via phosphorylation of RelA/p65 at serine 276 in monocytes.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Cell Line; Cyclooxygenase 2; Gene Expression Regulation; I-kappa B Kinase; Lipopolysaccharides; Mice; Monocytes; p300-CBP Transcription Factors; Peroxiredoxins; Phosphorylation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; ras Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2008 |
Phosphorylation of SNAP-25 at Ser187 mediates enhancement of exocytosis by a phorbol ester in INS-1 cells.
Topics: Animals; Botulinum Toxins, Type A; Calcium; Cattle; Cells, Cultured; Chromaffin Cells; Dose-Response Relationship, Radiation; Exocytosis; Gene Expression Regulation; Green Fluorescent Proteins; Insulinoma; Membrane Potentials; Mutation; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Rats; Serine; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Transfection | 2008 |
Posttranslational modifications on protein kinase c isozymes. Effects of epinephrine and phorbol esters.
Topics: Acetylglucosamine; Animals; Enzyme Activation; Epinephrine; Hepatocytes; Isoenzymes; Male; Mass Spectrometry; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Wistar; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2008 |
Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly.
Topics: Cell Line; Desmoplakins; Desmosomes; Enzyme Activation; Humans; Models, Biological; Plakophilins; Protein Kinase C-alpha; Protein Transport; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2008 |
Histone H3 as a novel substrate for MAP kinase phosphatase-1.
Topics: Animals; Catalytic Domain; Chlorocebus aethiops; COS Cells; Dual Specificity Phosphatase 1; Endothelial Cells; Epigenesis, Genetic; Histones; Humans; Immunoprecipitation; Molecular Weight; Mutation; Peptide Fragments; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; RNA Interference; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Transfection; Vascular Endothelial Growth Factor A | 2009 |
S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Antineoplastic Agents; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Chromones; Cyclin B; Enzyme Inhibitors; Humans; Megakaryocytes; Morpholines; Nocodazole; Phosphoproteins; Phosphorylation; Polyploidy; Protein Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sirolimus; Tetradecanoylphorbol Acetate; Threonine; TOR Serine-Threonine Kinases; Wortmannin | 2009 |
Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription.
Topics: Activating Transcription Factor 2; ADP-Ribosylation Factors; Amino Acid Substitution; Animals; Carcinogens; E1A-Associated p300 Protein; HeLa Cells; Humans; Mice; Mice, Knockout; Mutation, Missense; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-jun; Response Elements; Serine; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2009 |
Phosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1.
Topics: Cell Division; Cell Nucleus; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; DNA Primers; Fibroblasts; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 2009 |
Differentiation-dependent interactions between RUNX-1 and FLI-1 during megakaryocyte development.
Topics: Animals; Cell Differentiation; Cell Line; Cells, Cultured; Core Binding Factor Alpha 2 Subunit; Electrophoresis, Polyacrylamide Gel; Gene Expression; Humans; Liver; Megakaryocytes; Mice; Mice, Inbred C57BL; Models, Biological; Mutation; Phosphorylation; Protein Binding; Protein Interaction Mapping; Proto-Oncogene Protein c-fli-1; Serine; Tetradecanoylphorbol Acetate | 2009 |
Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene.
Topics: Binding Sites; Blotting, Western; Cell Line; Chromatin Immunoprecipitation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gene Expression; Histones; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Signal Transduction; Sp1 Transcription Factor; T-Box Domain Proteins; Tetradecanoylphorbol Acetate | 2009 |
Neurotrophins induce neuregulin release through protein kinase Cdelta activation.
Topics: Acetophenones; Amino Acid Sequence; Animals; Avian Proteins; Benzopyrans; Blotting, Western; Cells, Cultured; Chick Embryo; Chickens; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Ganglia, Spinal; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Neuregulin-1; Neurons; PC12 Cells; Phosphorylation; Protein Kinase C-delta; Rats; RNA Interference; Serine; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Critical role of s465 in protein kinase C-increased rat glutamate transporter type 3 activity.
Topics: Anesthetics, Inhalation; Animals; Data Interpretation, Statistical; DNA, Complementary; Electrophysiology; Excitatory Amino Acid Transporter 3; Female; Isoflurane; Oocytes; Patch-Clamp Techniques; Phorbol Esters; Phosphorylation; Protein Kinase C; Rats; Serine; Tetradecanoylphorbol Acetate; Xenopus laevis | 2009 |
Site-specific connexin phosphorylation is associated with reduced heterocellular communication between smooth muscle and endothelium.
Topics: Animals; Arterioles; Calcium; Cell Communication; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclic AMP; Endothelial Cells; Fibroblast Growth Factor 2; Gap Junctions; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Protein Processing, Post-Translational; Serine; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.
Topics: Actins; Algorithms; Amino Acid Substitution; Animals; Cell Line, Tumor; Chlorocebus aethiops; Cortactin; Cytoskeleton; Fluorescence Recovery After Photobleaching; Focal Adhesions; Green Fluorescent Proteins; Humans; Kinetics; Membrane Glycoproteins; Microfilament Proteins; Models, Biological; Phosphorylation; Protein Binding; Protein Kinase C-delta; Protein Transport; Recombinant Fusion Proteins; RNA Interference; Serine; Tetradecanoylphorbol Acetate; Transfection; Vero Cells | 2010 |
Ser123 is essential for the water channel activity of McPIP2;1 from Mesembryanthemum crystallinum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Aquaporins; Mesembryanthemum; Molecular Sequence Data; Mutagenesis, Site-Directed; Okadaic Acid; Oocytes; Permeability; Plant Proteins; Serine; Tetradecanoylphorbol Acetate; Water; Xenopus laevis | 2010 |
Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes.
Topics: Amino Acid Substitution; Animals; Arabidopsis Proteins; Electrophysiological Phenomena; Naphthalenes; Oocytes; Phosphorylation; Potassium Channels, Inwardly Rectifying; Protein Interaction Domains and Motifs; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Threonine; Transfection; Xenopus laevis | 2010 |
Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells.
Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Glioma; Glutathione S-Transferase pi; Humans; Indoles; Maleimides; Phosphorylation; Protein Kinase C-alpha; Protein Transport; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate | 2010 |
PKC alpha phosphorylates cytosolic NF-kappaB/p65 and PKC delta delays nuclear translocation of NF-kappaB/p65 in U1242 glioblastoma cells.
Topics: Cell Line, Tumor; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Glioblastoma; Humans; Indoles; Maleimides; NF-kappa B; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 2010 |
K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function.
Topics: Amino Acid Sequence; Animals; Calmodulin; Immunoprecipitation; Mice; Molecular Sequence Data; NIH 3T3 Cells; Protein Kinase C; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Serine; Tetradecanoylphorbol Acetate | 2010 |
IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI.
Topics: Cell Line; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation; Humans; Immunoprecipitation; Interleukin-2; Jurkat Cells; Lymphocyte Activation; Nuclear Factor 90 Proteins; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Serine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 2010 |
Protein kinase C-dependent phosphorylation of transient receptor potential canonical 6 (TRPC6) on serine 448 causes channel inhibition.
Topics: Amino Acid Substitution; Carbachol; Carcinogens; Cell Proliferation; Glomerulosclerosis, Focal Segmental; HEK293 Cells; Humans; Isoenzymes; Miotics; Mutation, Missense; Myocytes, Smooth Muscle; Phosphorylation; Protein Kinase C-delta; Serine; Tetradecanoylphorbol Acetate; TRPC Cation Channels; TRPC6 Cation Channel; Vasoconstrictor Agents; Vasopressins | 2010 |
Climbing fiber-evoked Purkinje cell discharge reduces expression of GABA(A) receptor-associated protein and decreases its interaction with GABA(A) receptors.
Topics: Action Potentials; Afferent Pathways; Animals; Antibodies; Apoptosis Regulatory Proteins; Carrier Proteins; Cerebellum; Cytoskeletal Proteins; Gene Expression Regulation; Immunoprecipitation; Membrane Proteins; Mice; Microtubule-Associated Proteins; Nystagmus, Optokinetic; Phosphorylation; Photic Stimulation; Protein Phosphatase 1; Protein Phosphatase 2; Purkinje Cells; Rabbits; Receptors, GABA-A; RNA, Messenger; Serine; Tetradecanoylphorbol Acetate; Tubulin | 2011 |
Ser756 of β2 integrin controls Rap1 activity during inside-out activation of αMβ2.
Topics: Animals; Antibodies; CD18 Antigens; Chlorocebus aethiops; COS Cells; Erythrocytes; Gene Expression Regulation; Humans; Macrophage-1 Antigen; Macrophages; Mutation; rap1 GTP-Binding Proteins; Serine; Sheep; Talin; Tetradecanoylphorbol Acetate | 2011 |
Protein kinase C stabilizes X-linked inhibitor of apoptosis protein (XIAP) through phosphorylation at Ser(87) to suppress apoptotic cell death.
Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Apoptosis; Brain; Cell Death; Cell Line, Tumor; Etoposide; Humans; Neuroblastoma; Neurons; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Transfection; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Identification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number.
Topics: Actins; Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion Molecules; Cell Line; Cell Movement; Cytoskeleton; Focal Adhesions; Growth Hormone; Mice; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Transport; Serine; Signal Transduction; Substrate Cycling; Tetradecanoylphorbol Acetate | 2011 |
Brain-derived neurotrophic factor uses CREB and Egr3 to regulate NMDA receptor levels in cortical neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Chromatin Immunoprecipitation; CREB-Binding Protein; Electrophoretic Mobility Shift Assay; Embryo, Mammalian; Enzyme Inhibitors; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation; Humans; Luminescent Proteins; MAP Kinase Kinase Kinases; Neurons; Phosphorylation; Protein Binding; Rats; Receptor, trkB; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Zinc Fingers | 2012 |
Rab11 is phosphorylated by classical and novel protein kinase C isoenzymes upon sustained phorbol ester activation.
Topics: Computational Biology; Cytosol; Endosomes; HeLa Cells; Humans; Isoenzymes; Mass Spectrometry; Phosphorylation; Plasmids; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; rab GTP-Binding Proteins; Recombinant Fusion Proteins; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection; Transferrin | 2012 |
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.
Topics: Animals; Catechin; Cell Line; Curcumin; Enzyme Activation; Fatty Acids, Nonesterified; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Polyphenols; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
PMA induces GCMa phosphorylation and alters its stability via the PKC- and ERK-dependent pathway.
Topics: Animals; Antibodies, Monoclonal; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Hybridomas; MAP Kinase Signaling System; Mice; Neuropeptides; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Stability; Serine; Tetradecanoylphorbol Acetate; Transcription Factors | 2012 |
PKCα phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity.
Topics: Amino Acid Sequence; HEK293 Cells; Humans; Models, Molecular; Phosphorylation; Protein Kinase C-alpha; rac1 GTP-Binding Protein; rho Guanine Nucleotide Dissociation Inhibitor beta; Serine; Tetradecanoylphorbol Acetate; Transfection | 2013 |
Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytes.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Endoplasmic Reticulum Stress; Enzyme Activators; Hepatocytes; Humans; Insulin; Insulin Resistance; Isoenzymes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Protein Kinase C-alpha; Protein Processing, Post-Translational; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
PMA-induced GCMa phosphorylation stimulates its transcriptional activity and degradation.
Topics: Cell Differentiation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HEK293 Cells; Humans; MAP Kinase Signaling System; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Stability; Proteolysis; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Trophoblasts; Ubiquitination | 2012 |
NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Cells, Cultured; Enzyme Activation; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Phagocytes; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Serine; Superoxides; Tetradecanoylphorbol Acetate; Transfection | 2013 |
A novel effect of MARCKS phosphorylation by activated PKC: the dephosphorylation of its serine 25 in chick neuroblasts.
Topics: Amino Acid Sequence; Animals; Cell Differentiation; Chick Embryo; Chickens; Conserved Sequence; Cyclin-Dependent Kinase 5; Evolution, Molecular; Female; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Neurons; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Retina; Serine; Tetradecanoylphorbol Acetate | 2013 |
Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways.
Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Angiotensin II; Blotting, Western; Cell Line, Tumor; EGF Family of Proteins; Enzyme Activation; Epidermal Growth Factor; Flow Cytometry; Glycoproteins; HEK293 Cells; Humans; Intercellular Signaling Peptides and Proteins; Isoenzymes; Jurkat Cells; Ligands; Phosphorylation; Protein Kinase C; Proteins; Proteolysis; RNA Interference; Serine; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2013 |
Serine phosphorylation sites on IRS2 activated by angiotensin II and protein kinase C to induce selective insulin resistance in endothelial cells.
Topics: Angiotensin II; Animals; Cattle; Cell Line; Endothelial Cells; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Zucker; Serine; Tetradecanoylphorbol Acetate; Threonine; Tyrosine | 2013 |
Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Humans; Immunoblotting; Isomerism; Lipopolysaccharides; Lipoxygenase; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Peroxidase; Phosphorylation; Prostaglandins; Reactive Oxygen Species; Serine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2014 |
Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.
Topics: Binding Sites; Burkitt Lymphoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Marine Toxins; Myeloid Cell Leukemia Sequence 1 Protein; Okadaic Acid; Oxazoles; Phosphorylation; Protein Phosphatase 2; Proteolysis; Serine; Tetradecanoylphorbol Acetate; Threonine | 2014 |
Suppression of PKCε-mediated mitochondrial connexin 43 phosphorylation at serine 368 is involved in myocardial mitochondrial dysfunction in a rat model of dilated cardiomyopathy.
Topics: Administration, Oral; Animals; Cardiomyopathy, Dilated; Cells, Cultured; Connexin 43; Disease Models, Animal; Electron Transport Complex IV; Furazolidone; Glycyrrhetinic Acid; Membrane Potential, Mitochondrial; Mitochondria, Heart; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serine; Succinate Dehydrogenase; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2015 |
QRFP-43 inhibits lipolysis by preventing ligand-induced complex formation between perilipin A, caveolin-1, the catalytic subunit of protein kinase and hormone-sensitive lipase in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Carrier Proteins; Caveolin 1; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclic Nucleotide Phosphodiesterases, Type 3; Dose-Response Relationship, Drug; Enzyme Activation; Intercellular Signaling Peptides and Proteins; Isoproterenol; Lipid Droplets; Lipolysis; Mice; Multiprotein Complexes; Peptides; Perilipin-1; Phosphodiesterase 3 Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Transport; Receptors, G-Protein-Coupled; Serine; Signal Transduction; src-Family Kinases; Sterol Esterase; Tetradecanoylphorbol Acetate | 2015 |
Phospholipid flippase ATP11C is endocytosed and downregulated following Ca
Topics: Adenosine Triphosphatases; Amino Acid Motifs; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Calcium; Calcium Signaling; Cell Line; Down-Regulation; Endocytosis; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gq-G11; HeLa Cells; Humans; Membrane Transport Proteins; Mice; Phosphorylation; Protein Kinase C-alpha; Serine; Tetradecanoylphorbol Acetate | 2017 |
TRESK (K2P18.1) Background Potassium Channel Is Activated by Novel-Type Protein Kinase C via Dephosphorylation.
Topics: Animals; Animals, Genetically Modified; Calcineurin; Humans; Mutation; Phosphorylation; Potassium Channels; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate; Xenopus laevis | 2019 |