tetradecanoylphorbol acetate has been researched along with piperidines in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.77) | 18.7374 |
| 1990's | 25 (47.17) | 18.2507 |
| 2000's | 15 (28.30) | 29.6817 |
| 2010's | 9 (16.98) | 24.3611 |
| 2020's | 2 (3.77) | 2.80 |
| Authors | Studies |
|---|---|
| Annat, J; Derrepas, P; Dutartre, P; Pascal, M | 1 |
| Burch, RM; Connor, JR; Shearer, BG; Sullivan, JP; Tiffany, C | 1 |
| Emori, T; Hirata, Y; Marumo, F; Ohta, K; Shichiri, M | 1 |
| Daly, JW; Gusovsky, F; McNeal, ET | 1 |
| Chemeris, NK; Gapeev, AB; Obraztsov, VV; Sadovnikov, VB; Safronova, VG; Shekhtman, DG; Sklifas, AN; Sukharev, SA | 1 |
| Ansorge, S; Kähne, T; Neubert, K | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Jiang, H; Kato, R; Yamamoto, S | 2 |
| Gopalakrishnan, V; Herman, RJ; Sandirasegarane, L | 1 |
| Bollen, M; De Smedt, H; Himpens, B | 1 |
| Ishikawa, S; Okada, K; Saito, T; Sasaki, R | 1 |
| Eraly, SA; Mellon, PL; Wetsel, WC; Whyte, DB | 1 |
| Bouaboula, M; Bourrié, B; Calandra, B; Canat, X; Casellas, P; Le Fur, G; Poinot-Chazel, C; Rinaldi-Carmona, M | 1 |
| Hirai, S; Kosaka, K; Mizuno, K; Nishioka, N; Ohno, S; Osada, S; Suzuki, A | 1 |
| Lin, Q; Peng, YB; Willis, WD | 2 |
| Murayama, T; Nomura, Y; Oda, H | 1 |
| Conway, AM; Pyne, NJ; Pyne, S; Tolan, D | 1 |
| Andersson-Ross, C; Barkhem, T; Höglund, M; Nilsson, S | 1 |
| Barbosa, J; Clarizia, AD; Gomez, MV; Prado, MA; Prado, VF; Romano-Silva, MA | 1 |
| Ishikawa, T; Menniti, FS; Mizutani, M; Nagahisa, A; Shimada, K; Shinjo, K; Taniguchi, K | 1 |
| Disashi, T; Inoue, J; Iwaoka, T; Kanesaka, Y; Naomi, S; Tokunaga, H; Tomita, K | 1 |
| Badger, AM; Breton, J; Chabot-Fletcher, M; Griswold, DE; Martin, LD | 1 |
| Díaz, E; Flores, I; Jones, DR; Martinez, C; Mérida, I | 1 |
| Ansorge, S; Faust, J; Kähne, T; Neubert, K | 1 |
| Abd-Elfattah, AS; Sholley, MM; Taher, MM | 1 |
| Henriques, MM; Rae, GA; Sampaio, AL | 1 |
| Apa, R; Garcia Pardo, M; Lanzone, A; Mancuso, S; Miceli, F; Minici, F; Navarra, P; Proto, C | 1 |
| Cartee, L; Chellappan, SP; Decker, RH; Dent, P; Fusaro, G; Grant, S; Hirsch, KG; Sankala, HM; Wang, Z | 1 |
| Lu, JY; Wu, BW; Wu, DM | 1 |
| Almenara, J; Cartee, L; Dai, Y; Dent, P; Grant, S; Rahmani, M; Rosato, R; Smith, R | 1 |
| Jenks, BG; Lieste, JR; Roubos, EW; Scheenen, WJ; Schoenmakers, TJ; Willems, PH | 1 |
| Blacker, M; Carty, TJ; Goodyer, CG; LeBlanc, AC; Noe, MC | 1 |
| de Mello, FG; de Mello, MC; Gardino, PF; Loureiro-dos-Santos, NE; Prado, MA; Reis, RA | 1 |
| Fresco, P; Gonçalves, J; Pinto, E; Pinto, M; Saraiva, L; Sousa, E | 1 |
| Jardemark, KE; Liang, X; Ninan, I; Wang, RY | 1 |
| Ahluwalia, J; Bevan, S; Nagy, I; Urban, L | 1 |
| Hirate, K; Irifune, M; Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K; Teramoto, T | 1 |
| Hayashi, K; Ikeda, K; Inoue, S; Kuno, S; Ohta, K; Ohta, M; Toyomoto, M | 1 |
| Aguilar-Quesada, R; García Del Moral, R; Martin-Oliva, D; Martínez-Romero, R; Muñoz-Gámez, JA; O'valle, F; Oliver, FJ; Piris, MA; Ruiz de Almodóvar, JM; Villuendas, R | 1 |
| Hirasawa, N; Hong, J; Ishihara, K; Katoh, G; Ohsawa, Y; Ohuchi, K; Seyama, T; Shibata, K; Tamura, S | 1 |
| Bult, H; Cos, P; Deschacht, M; Horemans, T; Maes, L; Martinet, W | 1 |
| Dikalov, SI; Grigor'ev, IA; Kirilyuk, IA; Voinov, M | 1 |
| Hirasawa, N; Ohuchi, K | 1 |
| Choi, JH; Chung, YC; Han, EH; Hwang, YP; Jeong, HG; Kim, HG; Yun, HJ | 1 |
| Choi, JH; Chung, YC; Han, EH; Jang, WS; Jeong, HG; Khanal, T; Kim, HG; Park, BH; Tran, TP | 1 |
| Chen, X; Fagin, JA; Johnson, LK; Knauf, JA; Makarewicz, JM | 1 |
| Amulic, B; Sollberger, G; Zychlinsky, A | 1 |
| Han, Y; Mesplède, T; Quan, Y; Wainberg, MA; Xu, H | 1 |
| Mitchell, TS; Moots, RJ; Wright, HL | 1 |
| Jung, SH; Kang, SY; Kim, JM; Kim, JS; Lee, YR; Noh, EM; Park, BH; Park, J; Song, HK; Youn, HJ | 1 |
| Higashi, Y; Kataoka, T; Miyake, Y; Nakao, A; Tanaka, Y; Tanigaki, R | 1 |
1 review(s) available for tetradecanoylphorbol acetate and piperidines
| Article | Year |
|---|---|
[Roles of histamine in the exacerbated allergic dermatitis].
Topics: Animals; Cyclosporine; Dermatitis, Atopic; Disease Models, Animal; Drug Therapy, Combination; Histamine; Histamine Antagonists; Humans; Mice; Picryl Chloride; Piperidines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3; Receptors, Histamine H4; Tetradecanoylphorbol Acetate | 2011 |
52 other study(ies) available for tetradecanoylphorbol acetate and piperidines
| Article | Year |
|---|---|
Implications of prostaglandin E2 synthesis and phospholipase C activation in potentiation of T-cell proliferation by LF 1695.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Dinoprostone; Inositol Phosphates; Lymphocyte Activation; Mice; Piperidines; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
NPC 15437 interacts with the C1 domain of protein kinase C. An analysis using mutant PKC constructs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Binding Sites; Cell Line; DNA Mutational Analysis; Isoquinolines; Macromolecular Substances; Molecular Sequence Data; Mutation; Phorbol 12,13-Dibutyrate; Piperazines; Piperidines; Protein Conformation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Vasoconstrictor-induced heterologous down-regulation of vascular atrial natriuretic peptide receptor.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cyclic GMP; Humans; In Vitro Techniques; Iodine Radioisotopes; Muscle, Smooth, Vascular; Piperidines; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1989 |
Cardiotonic activities of pumiliotoxin B, pyrethroids and a phorbol ester and their relationships with phosphatidylinositol turnover.
Topics: Alkaloids; Amphibian Venoms; Animals; Atrial Function; Cardiotonic Agents; Guinea Pigs; Heart Atria; In Vitro Techniques; Indolizines; Male; Myocardial Contraction; Myocardium; Phosphatidylinositols; Piperidines; Pyrethrins; Tetradecanoylphorbol Acetate | 1987 |
[A perfluorocarbon emulsion inhibits neutrophil activation].
Topics: Animals; Blood Substitutes; Cell Membrane; Emulsions; Enzyme Activation; Fluorocarbons; In Vitro Techniques; Luminescent Measurements; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Peritoneal Cavity; Piperidines; Protein Kinase C; Signal Transduction; Specific Pathogen-Free Organisms; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Enzymatic activity of DPIV/CD26 is involved in PMA-induced hyperphosphorylation of p56lck.
Topics: Dipeptidyl Peptidase 4; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; src-Family Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles | 1995 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Anti-inflammatory action of orally active 5-lipoxygenase inhibitor TMK688.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase Inhibitors; Dermatitis, Contact; Dinoprostone; Dose-Response Relationship, Drug; Female; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Piperidines; Tetradecanoylphorbol Acetate | 1994 |
High glucose attenuates peptide agonist-evoked increases in cytosolic free [Ca2+] in rat aortic smooth muscle cells.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Arginine Vasopressin; Calcium; Cells, Cultured; Culture Media; Cytosol; Endothelins; Glucose; Male; Mannose; Muscle, Smooth, Vascular; Piperidines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Modulation of nucleocytosolic [Ca2+] gradient in smooth muscle by protein phosphorylation.
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Calcium; Cell Line; Cell Nucleus; Colforsin; Cricetinae; Cytosol; Diacylglycerol Kinase; Epidermal Growth Factor; Ethers, Cyclic; Homeostasis; Kinetics; Lactams, Macrocyclic; Leiomyosarcoma; Marine Toxins; Mesocricetus; Models, Biological; Muscle, Smooth; Okadaic Acid; Oxazoles; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Quinazolines; Quinazolinones; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Distinct inhibition by non-peptide and peptide arginine vasopressin antagonists of vasopressin-induced activation of mitogen-activated protein kinase in cultured rat vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Ionomycin; Muscle, Smooth, Vascular; Piperidines; Quinolones; Rats; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Arachidonate Lipoxygenases; Benzo(a)pyrene; Female; Indomethacin; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains; Piperidines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons.
Topics: Animals; Base Sequence; Cell Line, Transformed; Colforsin; Gonadotropin-Releasing Hormone; Hypothalamus; Molecular Sequence Data; Neurons; Oligonucleotide Probes; Piperidines; Protein Kinase C; Protein Kinases; Protein Precursors; Protein Processing, Post-Translational; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Analgesics; Animals; Benzoquinones; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cannabinoids; Cell Line; CHO Cells; Cricetinae; Cyclohexanols; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Immediate-Early Proteins; Kinetics; Lactams, Macrocyclic; Pertussis Toxin; Piperidines; Pyrazoles; Quinones; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Rifabutin; Rimonabant; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Virulence Factors, Bordetella | 1995 |
Wortmannin inhibits the activation of MAP kinase following vasopressin V1 receptor stimulation.
Topics: Androstadienes; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzazepines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Piperidines; Quinolones; Rats; Receptors, Vasopressin; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 1995 |
Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons.
Topics: Animals; Capsaicin; Female; Injections, Intradermal; Macaca fascicularis; Male; Neural Inhibition; Neurons; Periaqueductal Gray; Physical Stimulation; Piperidines; Protein Kinase C; Spinothalamic Tracts; Tetradecanoylphorbol Acetate | 1996 |
Involvement of protein kinase C in responses of rat dorsal horn neurons to mechanical stimuli and periaqueductal gray descending inhibition.
Topics: Animals; Dimethyl Sulfoxide; Electric Stimulation; Enzyme Activation; Lumbosacral Region; Neural Inhibition; Neurons; Periaqueductal Gray; Piperidines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Stress, Mechanical; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of inducible nitric oxide synthase expression by endothelin in rat glial cells prepared from the neonatal rat brain.
Topics: Animals; Animals, Newborn; Brain; Bucladesine; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Induction; Interleukin-1; Neuroglia; Nitric Oxide Synthase; Nitrites; Oligopeptides; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin B; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Sphingosine prevents diacylglycerol signaling to mitogen-activated protein kinase in airway smooth muscle.
Topics: 1-Butanol; Animals; Bradykinin; Butanols; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Kinetics; Muscle, Smooth; Palmitic Acid; Phosphatidate Phosphatase; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Platelet-Derived Growth Factor; Protein Kinase C; Quinazolines; Quinazolinones; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Trachea | 1997 |
Characterization of the "estrogenicity" of tamoxifen and raloxifene in HepG2 cells: regulation of gene expression from an ERE controlled reporter vector versus regulation of the endogenous SHBG and PS2 genes.
Topics: Alkaline Phosphatase; Carcinoma, Hepatocellular; Clone Cells; Estradiol; Estradiol Congeners; Estrogen Antagonists; Ethinyl Estradiol; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Kinetics; Liver Neoplasms; Piperidines; Placenta; Pregnancy; Protein Biosynthesis; Proteins; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Sex Hormone-Binding Globulin; Tamoxifen; Tetradecanoylphorbol Acetate; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
Effect of protein kinase C activation on the release of [3H]acetylcholine in the presence of vesamicol.
Topics: Acetylcholine; Animals; Carrier Proteins; Electric Stimulation; Enzyme Activation; Female; Hippocampus; In Vitro Techniques; Male; Membrane Transport Proteins; Phosphorylation; Piperidines; Protein Kinase C; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 1997 |
Antinociceptive activity of CP-101,606, an NMDA receptor NR2B subunit antagonist.
Topics: Analgesics, Non-Narcotic; Animals; Brain; Capsaicin; Carrageenan; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Subcutaneous; Male; Motor Activity; Pain Measurement; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetradecanoylphorbol Acetate | 1997 |
Endothelin-1 inhibits endothelin-converting enzyme-1 expression in cultured rat pulmonary endothelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Carcinogens; Cell Line; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Ionomycin; Ionophores; Lung; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Evaluation of the cutaneous anti-inflammatory activity of azaspiranes.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Cyclooxygenase 1; Dermatitis, Contact; Dinoprostone; Ear; Edema; Humans; Immunosuppressive Agents; Isoenzymes; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Monocytes; NF-kappa B; Peroxidase; Piperidines; Prostaglandin-Endoperoxide Synthases; Spiro Compounds; Tetradecanoylphorbol Acetate | 1998 |
Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation.
Topics: 3T3 Cells; Animals; Cell Line; Diacylglycerol Kinase; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-2; Isoenzymes; Mice; Phosphatidic Acids; Phospholipase D; Piperidines; Quinazolines; Quinazolinones; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1998 |
Early phosphorylation events induced by DPIV/CD26-specific inhibitors.
Topics: Calcium; CD3 Complex; Cyclic AMP; Dipeptidyl Peptidase 4; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lysine; Mitogens; Phosphorylation; Piperidines; Protease Inhibitors; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Tyrosine | 1998 |
Sphingosine induces phospholipase D and mitogen activated protein kinase in vascular smooth muscle cells.
Topics: Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Diacylglycerol Kinase; Enzyme Activation; Ethanol; Glycerophospholipids; Muscle, Smooth, Vascular; Phosphatidic Acids; Phospholipase D; Piperidines; Protein Kinase C; Quinazolines; Quinazolinones; Rats; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 1998 |
Role of endothelins on lymphocyte accumulation in allergic pleurisy.
Topics: Animals; Bosentan; CD4-Positive T-Lymphocytes; Chemotaxis, Leukocyte; Endothelin Receptor Antagonists; Endothelin-1; Humans; Interferon-gamma; Interleukin-4; Interleukin-5; Ionomycin; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Monensin; Oligopeptides; Ovalbumin; Peptides, Cyclic; Piperidines; Pleurisy; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Respiratory Hypersensitivity; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Endothelins enhance prostaglandin (PGE(2) and PGF(2alpha)) biosynthesis and release by human luteal cells: evidence of a new paracrine/autocrine regulation of luteal function.
Topics: Antihypertensive Agents; Cells, Cultured; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-3; Female; Humans; Kinetics; Oligopeptides; Piperidines; Progesterone; Tetradecanoylphorbol Acetate | 2001 |
The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells.
Topics: Apoptosis; Carrier Proteins; Caspases; Cell Cycle Proteins; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Membrane Potentials; Microtubule-Associated Proteins; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Piperidines; Protein Binding; Retinoblastoma Protein; Retinoblastoma-Binding Protein 1; Tetradecanoylphorbol Acetate; Transcription Factor DP1; Transcription Factors; Tumor Suppressor Proteins; U937 Cells | 2001 |
Class III anti-arrhythmia drug E-4031 potentiates Na+/Ca2+ exchange current in rat ventricular myocytes.
Topics: Animals; Anti-Arrhythmia Agents; Cell Separation; Heart Ventricles; Myocardium; Piperidines; Protein Kinase C; Pyridines; Rats; Sodium-Calcium Exchanger; Tamoxifen; Tetradecanoylphorbol Acetate | 2000 |
Synergistic induction of apoptosis in human myeloid leukemia cells by phorbol 12-myristate 13-acetate and flavopiridol proceeds via activation of both the intrinsic and tumor necrosis factor-mediated extrinsic cell death pathways.
Topics: Antineoplastic Agents; Apoptosis; Arabidopsis Proteins; Carcinogens; Caspase 8; Caspase 9; Caspases; Drug Synergism; Enzyme Precursors; Fatty Acid Desaturases; Flavonoids; Humans; Leukemia, Myeloid; Mitochondria; Piperidines; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; U937 Cells | 2002 |
TRH signal transduction in melanotrope cells of Xenopus laevis.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Melanocyte-Stimulating Hormones; Membrane Potentials; Piperidines; Pituitary Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyrotropin-Releasing Hormone; Xenopus laevis | 2002 |
Effect of tumor necrosis factor-alpha converting enzyme (TACE) and metalloprotease inhibitor on amyloid precursor protein metabolism in human neurons.
Topics: ADAM Proteins; ADAM17 Protein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Humans; Metalloendopeptidases; Neurons; Peptide Fragments; Piperidines; Protein Processing, Post-Translational; Sulfones; Tetradecanoylphorbol Acetate | 2002 |
Regulation of vesicular acetylcholine transporter by the activation of excitatory amino acid receptors in the avian retina.
Topics: Acetylcholine; Animals; Binding Sites; Carrier Proteins; Chick Embryo; Choline O-Acetyltransferase; Enzyme Inhibitors; Immunohistochemistry; Kainic Acid; Membrane Transport Proteins; Organ Culture Techniques; Phosphorylation; Piperidines; Presynaptic Terminals; Protein Kinase C; Receptors, Kainic Acid; Retina; Synaptic Transmission; Tetradecanoylphorbol Acetate; Up-Regulation; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2002 |
Inhibition of protein kinase C by synthetic xanthone derivatives.
Topics: Alkaloids; Arachidonic Acid; Benzophenanthridines; Enzyme Inhibitors; Immunoblotting; Immunochemistry; Indicators and Reagents; Isoenzymes; Phenanthridines; Phenotype; Phosphatidylserines; Piperidines; Plasmids; Protein Kinase C; Saccharomyces cerevisiae; Tetradecanoylphorbol Acetate; Xanthines | 2003 |
Protein kinase C is involved in clozapine's facilitation of N-methyl-D-aspartate- and electrically evoked responses in pyramidal cells of the medial prefrontal cortex.
Topics: Alkaloids; Animals; Benzophenanthridines; Clozapine; Drug Interactions; Electric Stimulation; Electrophysiology; Enzyme Activators; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Fluorobenzenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Peptide Fragments; Phenanthridines; Phorbols; Piperidines; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Cannabinoids; Capsaicin; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Nerve Growth Factor; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2003 |
Facilitative effect of a novel AVP fragment analog, NC-1900, on memory retention and recall in mice.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Enzyme Activators; Male; Memory; Mental Recall; Mice; Mice, Inbred Strains; Oligopeptides; Phorbol Esters; Piperidines; Protein Kinase C; Pyrrolidonecarboxylic Acid; Receptors, Vasopressin; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2004 |
Production of NGF, BDNF and GDNF in mouse astrocyte cultures is strongly enhanced by a cerebral vasodilator, ifenprodil.
Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Glial Cell Line-Derived Neurotrophic Factor; Indoles; Maleimides; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Growth Factors; Piperidines; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Inhibition of poly(ADP-ribose) polymerase modulates tumor-related gene expression, including hypoxia-inducible factor-1 activation, during skin carcinogenesis.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Hypoxia-Inducible Factor 1, alpha Subunit; Isoquinolines; Mice; Mice, Inbred C57BL; NF-kappa B; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2006 |
Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.
Topics: Animals; Cell Count; Cimetidine; Cyclophosphamide; Cyclosporine; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ear Auricle; Eosinophil Peroxidase; Eosinophils; Gene Expression; Histamine; Histamine Antagonists; Immunoglobulin E; Interferon-gamma; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Picryl Chloride; Piperidines; Pyrilamine; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2009 |
Comparative EPR study of different macrophage types stimulated for superoxide and nitric oxide production.
Topics: Animals; Cell Line; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Endotoxins; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Organophosphates; Piperidines; Pyrrolidines; Spin Labels; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2010 |
EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines.
Topics: Anions; Cations; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Endothelial Cells; Humans; Hydrocarbons, Cyclic; Hydrophobic and Hydrophilic Interactions; Hydroxylamine; Hydroxylamines; Mitochondria; Neutrophils; Organophosphates; Permeability; Piperidines; Pyrrolidines; Rotenone; Spin Trapping; Static Electricity; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate | 2011 |
Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Benzodioxoles; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Fibrosarcoma; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Protein Kinase C-alpha; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2011 |
Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages.
Topics: Alkaloids; Animals; Benzodioxoles; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Line; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme Activation; Humans; Macrophages; Mice; NF-kappa B; Piperidines; Polyunsaturated Alkamides; Protein Kinases; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2012 |
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Enzyme Inhibitors; Farnesyltranstransferase; Gene Dosage; Gene Knock-In Techniques; Genes, ras; Humans; Mice, Mutant Strains; Mutation; Papilloma; Piperidines; Pyridines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression.
Topics: Animals; Candida albicans; Chemokine CCL3; Cycloheximide; Dactinomycin; Extracellular Traps; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Lipopolysaccharides; Male; Mice; Neutrophils; Piperidines; Primary Cell Culture; RNA Polymerase II; RNA Polymerase III; Salmonella typhimurium; Tetradecanoylphorbol Acetate | 2016 |
JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1.
Topics: Binding Sites; CD4 Antigens; CD4-Positive T-Lymphocytes; env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Interleukin-2; Janus Kinases; Nitriles; Piperidines; Pyrazoles; Pyrimidines; Pyrroles; Pyrrolidines; Signal Transduction; STAT Transcription Factors; Sulfonamides; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Virus Internalization; Virus Replication | 2017 |
Janus kinase inhibitors prevent migration of rheumatoid arthritis neutrophils towards interleukin-8, but do not inhibit priming of the respiratory burst or reactive oxygen species production.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azetidines; Case-Control Studies; Cell Movement; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Janus Kinases; Male; Middle Aged; Neutrophils; Piperidines; Protein Kinase Inhibitors; Purines; Pyrazoles; Pyrimidines; Pyrroles; Reactive Oxygen Species; Respiratory Burst; Sulfonamides; Tetradecanoylphorbol Acetate; United Kingdom | 2017 |
Bruton's agammaglobulinemia tyrosine kinase (Btk) regulates TPA‑induced breast cancer cell invasion via PLCγ2/PKCβ/NF‑κB/AP‑1‑dependent matrix metalloproteinase‑9 activation.
Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Breast Neoplasms; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Invasiveness; NF-kappa B; Phospholipase C gamma; Piperidines; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2021 |
Small Molecule Inhibitors Targeting Nuclear Factor κB Activation Markedly Reduce Expression of Interleukin-2, but Not Interferon-γ, Induced by Phorbol Esters and Calcium Ionophores.
Topics: Amides; Animals; Calcium Ionophores; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Interferon-gamma; Interleukin-2; Mice; NF-kappa B; Piperidines; Primary Cell Culture; Promoter Regions, Genetic; Pyrrolidines; Small Molecule Libraries; T-Box Domain Proteins; Tetradecanoylphorbol Acetate; Thiophenes | 2021 |