tetradecanoylphorbol acetate has been researched along with phosphoserine in 124 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (10.48) | 18.7374 |
| 1990's | 68 (54.84) | 18.2507 |
| 2000's | 30 (24.19) | 29.6817 |
| 2010's | 11 (8.87) | 24.3611 |
| 2020's | 2 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Min, HK; Park, DJ; Rhee, SG | 1 |
| Diglio, C; Du, YS; Kuo, TH; Tsang, W; Wang, KK | 1 |
| Adams, PD; Parker, PJ | 1 |
| Bird, TA; Saklatvala, J | 1 |
| Baker, MA; Civin, CI; Fackler, MJ; May, WS; Sutherland, DR | 1 |
| Farrar, WL; Linnekin, D | 1 |
| Druker, B; Griffin, JD; Kanakura, Y; Mamon, HJ; Okuda, K; Roberts, TM; Wood, KW | 1 |
| Angel, P; Boyle, WJ; Defize, LH; Hunter, T; Karin, M; Smeal, T; Woodgett, JR | 1 |
| Matsushima, K; Shiroo, M | 1 |
| Chakravarty, R; Rice, RH; Rong, XH | 1 |
| Garcia, JV; Miller, AD | 1 |
| Aguet, M; Ballotti, R; Mao, C; Merlin, G; Metzler, M | 1 |
| Kent, C; Watkins, JD | 1 |
| Duronio, V; Jacobs, S | 1 |
| Mueller-Lantzsch, N; Roeckel, D | 1 |
| Casnellie, JE; Lamberts, RJ | 1 |
| Harford, JB; Klausner, RD; Patel, MD; Samelson, LE; Weissman, AM | 1 |
| Cooper, JA; Kazlauskas, A | 1 |
| Schlossman, SF; Tedder, TF | 1 |
| Luttrell, DK; Luttrell, LM; Parsons, SJ; Rogol, AD | 1 |
| Bourguignon, LY; Kalomiris, EL | 1 |
| Fukuda, M; Piller, F; Piller, V | 1 |
| Kohno, H; Taketani, S; Tokunaga, R | 1 |
| Kahn, CR; Takayama, S; White, MF | 1 |
| Hagiwara, K; Hamada, H; Nakajima, T; Tsuruo, T | 1 |
| Harford, JB; Klausner, RD; Samelson, LE | 1 |
| Blackshear, PJ; Girard, PR; Kuo, JF; Quamo, SN; Witters, LA | 1 |
| Joel, PB; Lannigan, DA; Traish, AM | 1 |
| Berti, L; Häring, H; Kellerer, M; Kroder, G; Mosthaf, L; Mushack, J; Seedorf, K; Seffer, E; Tippmer, S | 1 |
| Pratt, MM; Salathe, M; Wanner, A | 1 |
| Cutler, RL; Krystal, G; Liu, L; Mui, AL | 1 |
| Cherqui, G; Plas, C; Zachayus, JL | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Hunter, T; Tracy, S; van der Geer, P | 1 |
| Boulay, F; Brouchon, L; Giannini, E | 1 |
| Ploegh, HL; Schaap, D; van Blitterswijk, WJ; van der Bend, RL; van der Wal, J | 1 |
| Bell, SM; Connolly, DC; Degen, JL; Maihle, NJ | 1 |
| Fujimoto, T; McEver, RP | 1 |
| Mueller, SG; Richmond, A; Schraw, WP | 1 |
| Abdullah, K; Cromlish, WA; Huang, Z; Kennedy, BP; Laliberté, F; Payette, P; Street, I | 1 |
| Liu, F; Roth, RA | 1 |
| Feener, EP; Hu, KQ; King, GL; Shiba, T; White, MF; Wilden, PA | 1 |
| Covarrubias, M; Salkoff, L; Vyas, TB; Wei, A | 1 |
| Bushfield, M; Houslay, MD; Lavan, BE; Morris, NJ | 1 |
| Babior, BM; el Benna, J; Faust, LP | 1 |
| Ascoli, M; Hipkin, RW; Quintana, J; Sánchez-Yagüe, J | 1 |
| Cooper, JA; Durden, DL; Rosen, H | 1 |
| Martin, J; Meenakshi, T; Ross, FP; Teitelbaum, SL | 1 |
| Matsumoto, N; Osawa, T; Toyoshima, S | 1 |
| Hogervorst, F; Kuikman, I; Noteboom, E; Sonnenberg, A | 1 |
| Hayashi, T; Imura, H; Inoue, G; Kono, S; Kosaki, A; Kuzuya, H; Nishimura, H; Okamoto, M; Yamada, K; Yoshimasa, Y | 1 |
| Kim, T; Park, I; Payne, NS; Shin, J; Strominger, JL; Walsh, CT; Winkler, DG | 1 |
| Bills, ND; Fontes, JD; Hinrichs, SH; Lewis, RE; Strawhecker, JM | 1 |
| Buggy, JJ; Heurich, RO; Rossomando, AJ; Vandenberg, MT | 1 |
| McCormick, F; Porfiri, E | 1 |
| Ohh, M; Takei, F | 1 |
| Kamata, Y; Kozaki, S; Nishiki, T; Omori, A; Sekiguchi, M; Shimazaki, Y; Takahashi, M | 1 |
| Deacon, E; Jardine, LJ; Lord, JM; McKendrick, L; Meek, DW; Milne, DM | 1 |
| Dolci, W; Thorens, B; Widmann, C | 1 |
| Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A | 1 |
| Canessa, M; Ceolotto, G; Clari, G; Conlin, P; Semplicini, A | 1 |
| Angel, P; Dieckmann, A; Pfisterer, P; Wirth, T; Zwilling, S | 1 |
| Ansotegui, IJ; Galron, D; Isakov, N | 1 |
| Ghoda, L; Greene, WC; Lin, X | 1 |
| Fucini, RV; Koretzky, GA; Li, YY; Pessin, JE; Ross, SE; Zhao, H | 1 |
| Byers, SW; Crockett, C; Jensen, JP; Orford, K; Weissman, AM | 1 |
| Olive, D; Parry, RV; Sansom, DM; Ward, SG; Westwick, J | 1 |
| Do, MT; Hébert, RL; Kennedy, CR; Proulx, PR | 1 |
| Bouchie, JL; Feener, EP; Folli, F; Hansen, H; Kahn, CR | 1 |
| Born, JL; Curry, MS; Edwards, BS; Gale, JM; Graf, LH; Robinson, MK; Salazar, F; Southon, EA | 1 |
| Evans, DL; Jaso-Friedmann, L; Leary, JH | 1 |
| Babior, BM; Benna, JE; Faust, LR; Inanami, O; Johnson, JL; McAdara, JK; Newburger, PE | 1 |
| Exton, JH; Min, DS | 1 |
| Mollerup, S; Rivedal, E; Sanner, T; Vikhamar, G | 1 |
| Kobayashi, Y; Kurosaka, K; Watanabe, N | 1 |
| Hann, SR; Lutterbach, B | 1 |
| Chatterjee, A; Feener, EP; Jiang, ZY; King, GL; Myers, MG; White, MF; Zhou, QL | 1 |
| Allis, CD; Bazett-Jones, DP; Chadee, DN; Davie, JR; Hendzel, MJ; Tylipski, CP; Wright, JA | 1 |
| Moelling, K; Zimmermann, S | 1 |
| Biden, TJ; Ludowyke, RI; Wilson, JR | 1 |
| Arai, K; Harada, Y; Miyatake, S; Watanabe, S | 1 |
| Junttila, I; Kovanen, PE; Li, W; Saharinen, P; Silvennoinen, O; Takaluoma, K; Valmu, L | 1 |
| Hu, CD; Kariya, K; Kataoka, T; Kotani, J; Okada, T; Sendoh, H; Shima, F; Song, C; Wu, D; Yamawaki-Kataoka, Y | 1 |
| Barnard, DS; Lin, A; Marshall, MS; Miao, W; Tzivion, G; Yip-Schneider, MT | 1 |
| Gåfvels, M; McCrae, KR; Sakthivel, R; Strickland, DK; Zhang, JC | 1 |
| Costa, M; Medcalf, RL; Shen, Y | 1 |
| Aramburu, J; García-Rodríguez, C; Hogan, PG; Okamura, H; Qin, J; Raghavan, A; Rao, A; Tahiliani, M; Viola, JP; Zhang, X | 1 |
| Chen, L; Guo, J; Hu, W; Ma, L; Pei, G; Xiang, B; Yu, GH | 1 |
| Chung, J; Jee, K; Kim, D; Kim, S; Koh, H | 1 |
| Dong, M; Eberhardt, NL; Jiang, SW; Miller, LJ; Trujillo, MA | 1 |
| Benovic, JL; Chalmers, C; Cook, SJ; Johnston, E; Palmer, TM; Pronin, A; Watterson, KR | 1 |
| Luo, Z; Ruderman, N; Song, Y; Wen, R; Xiang, X; Yuan, M | 1 |
| Buttrick, PM; Del Nido, P; Dowell, JC; Koretsky, AP; Montgomery, DE; Pyle, WG; Roman, BB; Solaro, RJ; Wolska, BM | 1 |
| Baraban, JM; Beretta, L; Dy, M; Grolleau, A; Machavoine, F; Rolli-Derkinderen, M | 1 |
| Bottini, N; Hyunh, H; Lombroso, PJ; Mustelin, T; Nika, K; Paul, S; Taskén, K; Williams, S | 1 |
| Batty, IH; Downes, CP; Fleming, IN | 1 |
| Anjum, R; Ballif, BA; Blenis, J; Gygi, SP; Roux, PP | 1 |
| Harper, DE; Parra-Palau, JL; Proud, CG; Scheper, GC | 1 |
| Chung, HJ; Huang, YH; Huganir, RL; Lau, LF | 1 |
| Campbell, DG; Mackintosh, C; Morrice, NA; Pozuelo Rubio, M | 1 |
| Armati, PJ; Mandadi, S; Murayama, N; Numazaki, M; Roufogalis, BD; Saito, N; Tominaga, M; Tominaga, T | 1 |
| Argetsinger, LS; Carter-Su, C; Cline, JM; Jensen, ON; Kouadio, JL; Mazurkiewicz-Munoz, AM; Stensballe, A | 1 |
| Dedman, JR; Kaetzel, MA; Li, B | 1 |
| Berna, MJ; Hoffmann, KM; Jensen, RT; Mantey, SA; Pace, A; Tapia, JA; Thill, M | 1 |
| Durgan, J; Michael, N; Parker, PJ; Totty, N | 1 |
| Kanazawa, H; Kuwahara, H; Nishizaki, M | 1 |
| Brattain, MG; Guo, LW; Spengler, ML | 1 |
| Cho, Y; Cunnick, J; Dorfleutner, A; Flynn, DC; Lin, H; Stehlik, C; Vincent, D; Weed, SA | 1 |
| Dai, C; Lee, SM; Lewis, TC; Muehlich, S; Prywes, R; Wang, R | 1 |
| Chen, X; Doshi, D; Katchman, A; Marx, SO; Morrow, J; Yang, L | 1 |
| Kochian, L; Ligaba, A; Piñeros, M | 1 |
| Mashima, K; Nakamura, K; Ozawa, T; Palmer, HE | 1 |
| Gan, L; Li, L | 1 |
| Asara, J; Cantley, LC; Chiu, YH; Lee, JY | 1 |
| Aragão, AZ; Granato, DC; Hoffman, Z; Honorato, RV; Laurindo, FR; Nogueira, ML; Oliveira, PS; Paes Leme, AF; Sherman, NE; Simabuco, FM; Squina, FM; Yokoo, S; Zeri, AC | 1 |
| Lazo, PA; Vázquez-Cedeira, M | 1 |
| Xia, C; Zhang, B | 1 |
| Bak, Y; Ham, SY; Hong, JT; Kang, JW; Kim, MS; Lee, DH; Park, SH; Park, YS; Yoon, DY | 1 |
| Dunn, CA; Lampe, PD | 1 |
| Chung, J; Joo, SY; Kang, D; Koo, MY; Lim, JM; Park, J; Rhee, SG; Shim, HB; Shin, SP; Woo, HA | 1 |
| Bak, Y; Hong, J; Kang, JW; Kim, MS; Kim, S; Kwon, T; Park, YS; Yoon, DY | 1 |
| Brueggemann, LI; Byron, KL; Cribbs, LL; Denning, MF; Haick, JM; Schwartz, J | 1 |
| Chen, X; Gao, Q; He, Y; Li, H; Li, N; Lu, L; Qi, L; Su, H; Tang, J; Xu, T; Xu, Z | 1 |
| Alessi, DR; Chatterjee, D; Dorward, M; Gourlay, R; Karapetsas, A; Knapp, S; Lis, P; Malik, AU; Mathea, S; Nirujogi, RS; Pal, P; Polinski, NK; Purlyte, E; Taylor, M; Tonelli, F; Toth, R; Weidlich, S | 1 |
2 review(s) available for tetradecanoylphorbol acetate and phosphoserine
| Article | Year |
|---|---|
New insights into the regulation of ICAM-1 gene expression.
Topics: Animals; Antigens, CD; Binding Sites; Cell Adhesion Molecules; Cycloheximide; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Phosphoserine; Phosphothreonine; Protein Synthesis Inhibitors; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Receptor associated phosphorylation following monoclonal antibody or synthetic peptide binding to nonspecific cytotoxic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Cytotoxicity, Immunologic; Genistein; Ictaluridae; Isoquinolines; Killer Cells, Natural; Molecular Sequence Data; Oxazolone; Peptides; Phosphorylation; Phosphoserine; Protein Kinase C; Quinolines; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
122 other study(ies) available for tetradecanoylphorbol acetate and phosphoserine
| Article | Year |
|---|---|
Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Kinetics; Muromonab-CD3; Peptide Mapping; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases; Tyrosine | 1992 |
Hormone-induced phosphorylation of the plasma membrane calcium pump in cultured aortic endothelial cells.
Topics: Animals; Aorta, Thoracic; Biological Transport, Active; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Enzyme Activation; Hormones; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Thionucleotides | 1991 |
TPA-induced activation of MAP kinase.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Humans; In Vitro Techniques; Molecular Sequence Data; Molecular Weight; Peptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1991 |
Down-modulation of epidermal growth factor receptor affinity in fibroblasts treated with interleukin 1 or tumor necrosis factor is associated with phosphorylation at a site other than threonine 654.
Topics: Cell Line; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gingiva; Humans; Interleukin-1; Kinetics; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Threonine; Tumor Necrosis Factor-alpha; Tyrosine | 1990 |
Activated protein kinase C directly phosphorylates the CD34 antigen on hematopoietic cells.
Topics: Antigens, CD; Antigens, CD34; Antigens, Differentiation; Blotting, Western; Bryostatins; Enzyme Activation; Flow Cytometry; Growth Substances; Hematopoietic Stem Cells; Humans; Lactones; Macrolides; Molecular Weight; Peptide Mapping; Phosphorylation; Phosphoserine; Protein Kinase C; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1990 |
Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoenzymes; Kinetics; Phosphates; Phosphoserine; Phosphotyrosine; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line.
Topics: Cell Line; Ethers, Cyclic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interleukin-3; Okadaic Acid; Phosphorylation; Phosphoserine; Precipitin Tests; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Vanadates | 1991 |
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity.
Topics: Amino Acid Sequence; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme Activation; Glycogen Synthase Kinases; HeLa Cells; Humans; In Vitro Techniques; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factors | 1991 |
Enhanced phosphorylation of 65 and 74 kDa proteins by tumor necrosis factor and interleukin-1 in human peripheral blood mononuclear cells.
Topics: Cell Compartmentation; Cell Membrane; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Humans; In Vitro Techniques; Interleukin-1; Leukocytes, Mononuclear; Phosphoproteins; Phosphorylation; Phosphoserine; Prednisolone; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Phorbol ester-stimulated phosphorylation of keratinocyte transglutaminase in the membrane anchorage region.
Topics: Binding Sites; Cell Membrane; Cells, Cultured; Humans; Immunosorbent Techniques; Keratinocytes; Peptide Fragments; Phosphates; Phosphorylation; Phosphoserine; Protein Kinase C; Tetradecanoylphorbol Acetate; Transglutaminases; Trypsin | 1990 |
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.
Topics: Antigens, CD; B-Lymphocytes; CD4 Antigens; Cell Line; Down-Regulation; Fluorescent Antibody Technique; Gene Expression Regulation; Gene Products, nef; Genetic Vectors; HIV; HIV Long Terminal Repeat; Humans; Moloney murine leukemia virus; Monocytes; nef Gene Products, Human Immunodeficiency Virus; Phosphorylation; Phosphoserine; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Rapid increase of the human IFN-gamma receptor phosphorylation in response to human IFN-gamma and phorbol myristate acetate. Involvement of different serine/threonine kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Humans; In Vitro Techniques; Interferon-gamma; Isoquinolines; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Piperazines; Protein Kinases; Receptors, Immunologic; Receptors, Interferon; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Phosphorylation of CTP:phosphocholine cytidylyltransferase in vivo. Lack of effect of phorbol ester treatment in HeLa cells.
Topics: Animals; Antibodies; Cell Membrane Permeability; Choline-Phosphate Cytidylyltransferase; Chromatography, Affinity; Chromatography, Ion Exchange; Cytosol; Digitonin; HeLa Cells; Humans; Kinetics; Liver; Molecular Weight; Nucleotidyltransferases; Phosphorylation; Phosphoserine; Rats; Tetradecanoylphorbol Acetate | 1990 |
The effect of protein kinase-C inhibition on insulin receptor phosphorylation.
Topics: Alkaloids; Cell Line; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Insulin; Peptide Mapping; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Receptor, Insulin; Staurosporine; Tetradecanoylphorbol Acetate; Trypsin | 1990 |
Biochemical characterization of two Epstein-Barr virus early antigen-associated phosphopolypeptides.
Topics: Antibodies, Monoclonal; Antigens, Viral; Cell Line; Chromatin; DNA; DNA-Binding Proteins; Herpesvirus 4, Human; Humans; Molecular Weight; Phosphopeptides; Phosphoserine; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine; Viral Proteins | 1985 |
Tumor promoters cause changes in the state of phosphorylation and apparent molecular weight of a tyrosine protein kinase in T lymphocytes.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Immunologic Techniques; Immunosorbent Techniques; Lymphoma; Mice; Molecular Weight; Phorbols; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor.
Topics: Animals; Antigens; Isoelectric Point; Lymphocyte Activation; Macromolecular Substances; Membrane Proteins; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1986 |
Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.
Topics: Animals; Cell Line; Immunoassay; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1988 |
Phosphorylation of the B1 (CD20) molecule by normal and malignant human B lymphocytes.
Topics: Antibodies; Antigens; Antigens, CD20; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Electrophoresis, Polyacrylamide Gel; Humans; Immunosorbent Techniques; Kinetics; Leukemia, Lymphoid; Molecular Weight; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Insulin and phorbol ester induce distinct phosphorylations of pp60c-src in the BC3H-1 murine myocyte cell line.
Topics: Animals; Cell Line; Cyclic AMP; Insulin; Mice; Muscles; Peptide Mapping; Phosphorylation; Phosphoserine; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Tetradecanoylphorbol Acetate | 1989 |
Lymphoma protein kinase C is associated with the transmembrane glycoprotein, GP85, and may function in GP85-ankyrin binding.
Topics: Animals; Ankyrins; Blood Proteins; Calcium; Cell Membrane; Cytoskeleton; Fluorescent Antibody Technique; Histones; Hyaluronan Receptors; Immunosorbent Techniques; Isoelectric Point; Lymphoma; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred AKR; Molecular Weight; Phospholipids; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Cell Surface; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Phosphorylation of the major leukocyte surface sialoglycoprotein, leukosialin, is increased by phorbol 12-myristate 13-acetate.
Topics: Alkaloids; Amino Acid Sequence; Antigens, CD; Blood Platelets; Cell Line; Erythrocytes; Granulocytes; Humans; Kinetics; Leukosialin; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Phosphates; Phosphorylation; Phosphoserine; Protein Kinase C; Sialoglycoproteins; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Expression and phosphorylation of transferrin receptors in mitogen-activated peripheral blood lymphocytes.
Topics: Blood Physiological Phenomena; Cells, Cultured; Concanavalin A; Humans; Lymphocyte Activation; Lymphocytes; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Receptors, Transferrin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transferrin | 1985 |
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Chromatography, Affinity; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphoserine; Phosphothreonine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1988 |
Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters.
Topics: Antibodies, Monoclonal; Calmodulin; Drug Resistance; Glycoproteins; Humans; Molecular Weight; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Tetradecanoylphorbol Acetate; Trifluoperazine; Verapamil | 1987 |
Identification of the components of the murine T cell antigen receptor complex.
Topics: Animals; Antibodies, Monoclonal; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Lymphocyte Activation; Mice; Models, Biological; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Growth factor-stimulated protein phosphorylation in 3T3-L1 cells. Evidence for protein kinase C-dependent and -independent pathways.
Topics: Animals; Brain; Cell Line; Diglycerides; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; Immunologic Techniques; Insulin; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1985 |
Estradiol and phorbol ester cause phosphorylation of serine 118 in the human estrogen receptor.
Topics: Animals; Base Sequence; Cell Compartmentation; Cell Nucleus; Cells, Cultured; Chlorocebus aethiops; Cyanogen Bromide; Enzyme Activation; Estradiol; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides; Peptide Mapping; Phosphoserine; Protein Kinase C; Receptors, Estrogen; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Glucose-induced translocation of protein kinase C isoforms in rat-1 fibroblasts is paralleled by inhibition of the insulin receptor tyrosine kinase.
Topics: 3-O-Methylglucose; Animals; Cell Line; Fibroblasts; Glucose; Humans; Insulin; Isoenzymes; Kinetics; Mannitol; Methylglucosides; Phosphates; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1994 |
Protein kinase C-dependent phosphorylation of a ciliary membrane protein and inhibition of ciliary beating.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Annexins; Carbazoles; Cell Fractionation; Cilia; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Erythrocytes; Indoles; Isoquinolines; Membrane Proteins; Movement; Phosphorylation; Phosphoserine; Phosphotyrosine; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sheep; Tetradecanoylphorbol Acetate; Trachea; Tyrosine | 1993 |
Steel factor stimulates the serine/threonine phosphorylation of the interleukin-3 receptor.
Topics: Animals; Cell Adhesion Molecules; Cell Division; Cell Line; DNA; Electrophoresis, Polyacrylamide Gel; Hematopoietic Cell Growth Factors; Interleukin-3; Kinetics; Macromolecular Substances; Mice; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Receptors, Interleukin-3; Recombinant Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Thymidine; Transfection | 1994 |
Protein kinase C and insulin receptor beta-subunit serine phosphorylation in cultured foetal rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Enzyme Activation; Glucose; Glycogen; Insulin; Liver; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Rats; Receptor, Insulin; Swine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.
Topics: 3T3 Cells; Animals; Base Sequence; Cytoplasm; DNA Primers; Fluorescent Antibody Technique; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatases; Recombinant Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Identification of the major phosphorylation sites in human C5a anaphylatoxin receptor in vivo.
Topics: Amino Acid Sequence; Antigens, CD; Complement C5a; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Receptor, Anaphylatoxin C5a; Receptors, Complement; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
Differential modulation of plasminogen activator gene expression by oncogene-encoded protein tyrosine kinases.
Topics: Animals; Cell Transformation, Viral; Chick Embryo; DNA Mutational Analysis; Gene Expression Regulation, Enzymologic; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tyrosine; Urokinase-Type Plasminogen Activator | 1993 |
The cytoplasmic domain of P-selectin is phosphorylated on serine and threonine residues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Alprostadil; Amino Acid Sequence; Antigens, CD; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; P-Selectin; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phosphoserine; Phosphothreonine; Piperazines; Platelet Membrane Glycoproteins; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1993 |
Activation of protein kinase C enhances the phosphorylation of the type B interleukin-8 receptor and stimulates its degradation in non-hematopoietic cells.
Topics: Alkaloids; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Diglycerides; Down-Regulation; Enzyme Activation; Growth Substances; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Pertussis Toxin; Phosphorylation; Phosphoserine; Placenta; Protein Kinase C; Receptors, Interleukin; Receptors, Interleukin-8A; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 1995 |
Human cytosolic phospholipase A2 expressed in insect cells is extensively phosphorylated on Ser-505.
Topics: Animals; Base Sequence; Chlorocebus aethiops; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Phosphoserine; Recombinant Proteins; Spodoptera; Tetradecanoylphorbol Acetate | 1995 |
Identification of serines-1035/1037 in the kinase domain of the insulin receptor as protein kinase C alpha mediated phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; CHO Cells; Cricetinae; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Protein Kinase C; Receptor, Insulin; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection; Trypsin | 1994 |
Characterization of phorbol ester-stimulated serine phosphorylation of the human insulin receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; CHO Cells; Cricetinae; Electrophoresis, Polyacrylamide Gel; Epithelium; Humans; Insulin; Kidney; Kinetics; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Rats; Receptor, Insulin; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection; Trypsin | 1994 |
Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate.
Topics: Amino Acid Sequence; Animals; Diglycerides; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Phosphoserine; Potassium Channels; Protein Kinase C; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Xenopus laevis | 1994 |
Multi-site phosphorylation of the inhibitory guanine nucleotide regulatory protein Gi-2 occurs in intact rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Colforsin; Glucagon; GTP-Binding Proteins; Immunosorbent Techniques; Isoelectric Point; Liver; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trypsin; Vasopressins | 1994 |
The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases.
Topics: Amino Acid Sequence; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peptide Mapping; Phosphorylation; Phosphoserine; Proline-Directed Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate | 1994 |
Follitropin (FSH) and a phorbol ester stimulate the phosphorylation of the FSH receptor in intact cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Follicle Stimulating Hormone; Humans; Inositol Phosphates; Phorbol Esters; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Rats; Receptors, FSH; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Serine/threonine phosphorylation of the gamma-subunit after activation of the high-affinity Fc receptor for immunoglobulin G.
Topics: Amino Acid Sequence; Cell Line; Gene Expression; Humans; Immunoglobulin G; Interferon-gamma; Kinetics; Macromolecular Substances; Molecular Sequence Data; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Processing, Post-Translational; Receptors, IgG; Recombinant Proteins; Signal Transduction; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
1,25-Dihydroxyvitamin D3 and macrophage colony-stimulating factor-1 synergistically phosphorylate talin.
Topics: Alkaloids; Animals; Calcitriol; Cell Line; Drug Synergism; Genistein; Isoflavones; L Cells; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Staurosporine; Talin; Tetradecanoylphorbol Acetate | 1993 |
Characterization of the 50 kDa protein phosphorylated in concanavalin A-stimulated mouse T cells.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium-Binding Proteins; Chromatography, High Pressure Liquid; Concanavalin A; Electrophoresis, Gel, Two-Dimensional; Female; Lymphocyte Activation; Mice; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Phosphorylation; Phosphoserine; Phosphothreonine; Sequence Alignment; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
The role of phosphorylation in activation of the alpha 6A beta 1 laminin receptor.
Topics: Amino Acid Sequence; Base Sequence; DNA; Humans; Laminin; Leukemia, Erythroblastic, Acute; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Laminin; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Preparation of anti-phosphoserine and anti-phosphothreonine antibodies and their application in the study of insulin- and EGF-induced phosphorylation.
Topics: Animals; Antibodies; CHO Cells; Chromatography, Affinity; Cricetinae; Epidermal Growth Factor; ErbB Receptors; Humans; Insulin; Kinetics; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Rabbits; Receptor, Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck.
Topics: Amino Acid Sequence; Cell Line; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; HeLa Cells; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Peptides; Phosphopeptides; Phosphorylation; Phosphoserine; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine | 1993 |
Phorbol esters modulate the phosphorylation of human T-cell leukemia virus type I Tax.
Topics: Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Gene Products, tax; Mice; Mice, Transgenic; Molecular Sequence Data; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphoserine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells.
Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Glucagon; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Glucagon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; GRB2 Adaptor Protein; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Humans; Kinetics; Mice; Mutagenesis; Peptide Mapping; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Biosynthesis; Proteins; ras Guanine Nucleotide Exchange Factors; Recombinant Fusion Proteins; Recombinant Proteins; Sequence Deletion; Sequence Tagged Sites; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Phosphorylation of 25-kDa synaptosome-associated protein. Possible involvement in protein kinase C-mediated regulation of neurotransmitter release.
Topics: Animals; Antibodies, Monoclonal; Antigens; Botulinum Toxins; Membrane Proteins; Nerve Tissue Proteins; Neurotoxins; Norepinephrine; PC12 Cells; Phosphorylation; Phosphoserine; Potassium; Protein Kinase C; Qa-SNARE Proteins; Rats; SNARE Proteins; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 1996 |
Murine p53 is phosphorylated within the PAb421 epitope by protein kinase C in vitro, but not in vivo, even after stimulation with the phorbol ester o-tetradecanoylphorbol 13-acetate.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Binding Sites; DNA; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Mice; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1996 |
Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Chlorocebus aethiops; Cricetinae; Cricetulus; Cytoplasm; DNA Mutational Analysis; Down-Regulation; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Molecular Sequence Data; Peptides; Phosphorylation; Phosphoserine; Protein Kinase C; Rats; Receptors, Glucagon; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Phosphorylation of A 27-kDa protein correlates with survival of protein-synthesis-inhibited MCF-7 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Carcinoma; Cell Survival; Cycloheximide; Cytosol; Epidermal Growth Factor; Heat-Shock Proteins; Humans; Insulin-Like Growth Factor I; Isoelectric Point; Mitogens; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
Protein kinase C and insulin regulation of red blood cell Na+/H+ exchange.
Topics: Adult; Erythrocyte Membrane; Humans; Hydrogen-Ion Concentration; Insulin; Lithium; Membrane Proteins; Middle Aged; Phosphorylation; Phosphoserine; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1997 |
Inducible expression and phosphorylation of coactivator BOB.1/OBF.1 in T cells.
Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Cells, Cultured; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Homeodomain Proteins; Host Cell Factor C1; Humans; Immunosuppressive Agents; Ionomycin; Jurkat Cells; Lymphocyte Activation; Mice; Molecular Sequence Data; Octamer Transcription Factor-1; Phosphorylation; Phosphoserine; Recombinant Fusion Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcriptional Activation | 1997 |
Posttranslational regulation of Lck and a p36-38 protein by activators of protein kinase C: differential effects of the tumor promoter, PMA, and the non-tumor-promoter, bryostatin.
Topics: Adjuvants, Immunologic; Bryostatins; Carcinogens; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Lactones; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrolides; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro.
Topics: Animals; DNA-Binding Proteins; Enzyme Activation; Enzyme Induction; Gene Products, tax; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Protein Binding; Protein Serine-Threonine Kinases; Rats; Ribosomal Protein S6 Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Cells, Cultured | 1997 |
T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.
Topics: Adaptor Proteins, Signal Transducing; Calcium-Calmodulin-Dependent Protein Kinases; GRB2 Adaptor Protein; Humans; JNK Mitogen-Activated Protein Kinases; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Kinase 1; Membrane Proteins; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Receptors, Antigen, T-Cell; Signal Transduction; Son of Sevenless Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin.
Topics: Amino Acid Sequence; beta Catenin; Consensus Sequence; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Indoles; Maleimides; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Point Mutation; Protein Kinase C; Protein Processing, Post-Translational; Sequence Alignment; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Trans-Activators; Ubiquitins | 1997 |
Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.
Topics: B7-1 Antigen; CD28 Antigens; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Ligands; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1997 |
Bradykinin-stimulated arachidonic acid release from MDCK cells is not protein kinase C dependent.
Topics: Animals; Arachidonic Acid; Blotting, Western; Bradykinin; Calcimycin; Cell Line; Dogs; Drug Synergism; Enzyme Inhibitors; Indoles; Kidney; Kinetics; Maleimides; Phospholipases A; Phospholipases A2; Phosphorylation; Phosphoserine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Insulin; Insulin Receptor Substrate Proteins; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphoserine; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Receptors, Angiotensin; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Oxidant inhibition of alphaLbeta2 integrin adhesion: evidence for coordinate effects on conformation and cytoskeleton linkage.
Topics: Adenosine Triphosphate; Antibodies, Monoclonal; Arsenicals; Cell Adhesion; Cells, Cultured; Cytoskeleton; Humans; Integrins; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Oxidants; Oxidation-Reduction; Phosphoserine; Phosphothreonine; Signal Transduction; Sulfhydryl Compounds; Temperature; Tetradecanoylphorbol Acetate | 1998 |
Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304.
Topics: B-Lymphocytes; Base Sequence; Cells, Cultured; DNA Primers; Enzyme Activation; Humans; Leukocytes; Luminescent Measurements; Mutagenesis, Site-Directed; NADPH Oxidases; Phosphoproteins; Phosphorylation; Phosphoserine; Point Mutation; Recombinant Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Phospholipase D is associated in a phorbol ester-dependent manner with protein kinase C-alpha and with a 220-kDa protein which is phosphorylated on serine and threonine.
Topics: Animals; Cell Line; Fibroblasts; Glutathione Transferase; Isoenzymes; Kinetics; Molecular Weight; Phospholipase D; Phosphoproteins; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Kinase C-alpha; Rats; Recombinant Fusion Proteins; Spodoptera; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Role of Cx43 phosphorylation and MAP kinase activation in EGF induced enhancement of cell communication in human kidney epithelial cells.
Topics: Antibodies; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Communication; Cell Line; Connexin 43; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Gap Junctions; Humans; Kidney; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Production of proinflammatory cytokines by phorbol myristate acetate-treated THP-1 cells and monocyte-derived macrophages after phagocytosis of apoptotic CTLL-2 cells.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Line; Cytokines; Humans; Inflammation; Interleukin-8; Macrophages; Mice; Monocytes; Oligopeptides; Phagocytosis; Phosphoserine; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
c-Myc transactivation domain-associated kinases: questionable role for map kinases in c-Myc phosphorylation.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Mice; Phosphopeptides; Phosphorylation; Phosphoserine; Protein Kinases; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate | 1999 |
Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.
Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Peptides, Cyclic; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphoserine; Protein Kinase C; Rats; Rats, Zucker; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatin; Epidermal Growth Factor; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, fos; Genes, myc; Genes, ras; Histones; Mice; Mitogens; Okadaic Acid; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transformation, Genetic | 1999 |
Phosphorylation and regulation of Raf by Akt (protein kinase B).
Topics: Cell Division; Cell Line; Chromones; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Humans; MAP Kinase Signaling System; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Fusion Proteins; Signal Transduction; Somatomedins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Increases in phosphorylation of the myosin II heavy chain, but not regulatory light chains, correlate with insulin secretion in rat pancreatic islets and RINm5F cells.
Topics: Animals; Cells, Cultured; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Myosin Heavy Chains; Myosin Light Chains; Myosin-Light-Chain Kinase; Pancreatic Neoplasms; Peptide Mapping; Phosphates; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Potassium Chloride; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Cyclic AMP inhibits the activity of c-Jun N-terminal kinase (JNKp46) but not JNKp55 and ERK2 in human helper T lymphocytes.
Topics: Antibodies; Bucladesine; Calcimycin; Cell Line; Cyclic AMP; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Weight; Myelin Basic Protein; Phosphorylation; Phosphoserine; Precipitin Tests; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1999 |
Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells.
Topics: Animals; Apoptosis; Catalysis; Cell Differentiation; Cell Division; DNA Replication; Enzyme Activation; Enzyme Induction; Interleukin-3; Isoenzymes; Janus Kinase 2; Macrophages; Mice; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Role of Raf-1 conserved region 2 in regulation of Ras-dependent Raf-1 activation.
Topics: Animals; COS Cells; Enzyme Activation; Fluorescence Polarization; Gene Expression Regulation, Enzymologic; Mutation; Phosphorylation; Phosphoserine; Protein Binding; Proto-Oncogene Proteins c-raf; rap1 GTP-Binding Proteins; ras Proteins; Tetradecanoylphorbol Acetate | 2000 |
Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.
Topics: 14-3-3 Proteins; Animals; Binding, Competitive; Catalytic Domain; COS Cells; Enzyme Activation; Mutation; Oncogene Protein pp60(v-src); Peptide Fragments; Phosphorylation; Phosphoserine; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 2000 |
Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation.
Topics: Cell Line; Endothelium, Vascular; Enzyme Activation; Glucose; Heymann Nephritis Antigenic Complex; Humans; Isoenzymes; Ligands; Membrane Glycoproteins; Phosphorylation; Phosphoserine; Plasminogen Activator Inhibitor 1; Protein Binding; Protein Kinase C; Receptors, LDL; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transfection; Urokinase-Type Plasminogen Activator | 2001 |
Overexpression of a dominant negative CREB protein in HT-1080 cells selectively disrupts plasminogen activator inhibitor type 2 but not tissue-type plasminogen activator gene expression.
Topics: Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Mutagenesis, Site-Directed; Phosphorylation; Phosphoserine; Plasminogen Activator Inhibitor 2; Recombinant Proteins; Repressor Proteins; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity.
Topics: Animals; Carcinogens; Conserved Sequence; DNA-Binding Proteins; Humans; Ionomycin; Ionophores; Jurkat Cells; Kidney; Mice; Molecular Sequence Data; Mutagenesis; NFATC Transcription Factors; Nuclear Localization Signals; Nuclear Proteins; Phosphorylation; Phosphoserine; Protein Conformation; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 2000 |
Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization.
Topics: Arrestins; beta-Arrestins; Calcium; Cell Line; Clathrin; Down-Regulation; Endocytosis; Enkephalin, D-Penicillamine (2,5)-; Humans; Mutation; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Kinetics; MAP Kinase Signaling System; Mice; Phosphatidylinositol 3-Kinases; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Proteins; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
DNA binding of TEA/ATTS domain factors is regulated by protein kinase C phosphorylation in human choriocarcinoma cells.
Topics: Amino Acid Sequence; Choriocarcinoma; DNA; DNA-Binding Proteins; Down-Regulation; Enhancer Elements, Genetic; Humans; Isoenzymes; Molecular Sequence Data; Nuclear Proteins; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Sequence Homology, Amino Acid; TEA Domain Transcription Factors; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2001 |
Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.
Topics: Animals; Base Sequence; beta-Adrenergic Receptor Kinases; Cell Line; Cricetinae; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Fibroblasts; Green Fluorescent Proteins; Humans; Immediate-Early Proteins; Kidney; Kinetics; Luminescent Proteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Polymerase Chain Reaction; Protein Kinase C; Protein Transport; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 2002 |
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Biological Transport; Cell Nucleus; COS Cells; Cytoplasm; Cytosol; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescent Antibody Technique; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Microscopy, Confocal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2002 |
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.
Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Binding Sites; Detergents; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Heart; Mice; Mice, Transgenic; Mutation; Myocardial Contraction; Papillary Muscles; Phenanthridines; Phenylephrine; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Troponin I | 2002 |
ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.
Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line; Chromones; Cycloheximide; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histidine Decarboxylase; Humans; Hypotonic Solutions; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Morpholines; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Repressor Proteins; Response Elements; RNA, Messenger; Sirolimus; Tetradecanoylphorbol Acetate; Transcription Factors | 2003 |
Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.
Topics: Antibodies; Ceramides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Subunits; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2004 |
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line, Tumor; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Receptor Substrate Proteins; Ionomycin; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase.
Topics: Amino Acid Sequence; Animals; Cell Line; Enzyme Activation; Humans; MAP Kinase Signaling System; Models, Biological; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Repressor Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2004 |
The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; Cytoplasm; Drosophila melanogaster; Drosophila Proteins; Enzyme Activation; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Phosphorylation; Phosphoserine; Protein Binding; Tetradecanoylphorbol Acetate | 2005 |
Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disks Large Homolog 4 Protein; Enzyme Activation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuronal Plasticity; Phosphorylation; Phosphoserine; Protein Interaction Mapping; Protein Kinase C; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Structure-Activity Relationship; Synapses; Tetradecanoylphorbol Acetate | 2004 |
Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.
Topics: 14-3-3 Proteins; 3-Phosphoinositide-Dependent Protein Kinases; 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Binding Sites; Cyclic Nucleotide Phosphodiesterases, Type 3; HeLa Cells; Humans; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate | 2005 |
Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antibody Specificity; Calcium; Capsaicin; Cell Line; CHO Cells; Cricetinae; Cricetulus; Ganglia, Spinal; HeLa Cells; Humans; Kidney; Mice; Molecular Sequence Data; Neurons, Afferent; Patch-Clamp Techniques; Peptide Fragments; Phosphorylation; Phosphoserine; Protein Kinase C-epsilon; Protein Processing, Post-Translational; Rabbits; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; TRPV Cation Channels | 2006 |
Phosphorylation of JAK2 at serine 523: a negative regulator of JAK2 that is stimulated by growth hormone and epidermal growth factor.
Topics: 3T3 Cells; Alanine; Animals; Butadienes; Cells, Cultured; Chlorocebus aethiops; COS Cells; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Growth Hormone; Humans; Janus Kinase 2; MAP Kinase Kinase 1; Mass Spectrometry; Mice; Mutation; Nitriles; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Repressor Proteins; STAT5 Transcription Factor; Tetradecanoylphorbol Acetate | 2006 |
Signaling pathways regulating murine cardiac CREB phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart; Isoenzymes; Isoproterenol; Mice; Molecular Sequence Data; Myocardial Reperfusion; Myocardium; Phosphorylation; Phosphoserine; Protein Kinase C-epsilon; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.
Topics: Animals; Bombesin; Calcium; Carbachol; Cholecystokinin; Dose-Response Relationship, Drug; Enzyme Activation; Growth Substances; Isoenzymes; Male; Mitogen-Activated Protein Kinases; Pancreas, Exocrine; Phosphoserine; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 2007 |
Novel phosphorylation site markers of protein kinase C delta activation.
Topics: Amino Acid Sequence; Animals; Biomarkers; Cell Line; Chlorocebus aethiops; Conserved Sequence; Enzyme Activation; Humans; Molecular Sequence Data; Phosphorylation; Phosphoserine; Protein Kinase C-delta; Sequence Alignment; Tetradecanoylphorbol Acetate | 2007 |
Nuclear localization signal and phosphorylation of Serine350 specify intracellular localization of DRAK2.
Topics: Amino Acid Sequence; Animals; Cell Nucleus; Chlorocebus aethiops; COS Cells; Intracellular Space; Mice; Molecular Sequence Data; NIH 3T3 Cells; Nuclear Localization Signals; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Rats; Sequence Deletion; Structure-Activity Relationship; Subcellular Fractions; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2008 |
Phosphorylation mediates Sp1 coupled activities of proteolytic processing, desumoylation and degradation.
Topics: Amino Acid Sequence; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Models, Biological; Molecular Sequence Data; Phosphorylation; Phosphoserine; Protein Kinase C-alpha; Protein Processing, Post-Translational; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells.
Topics: Amino Acid Sequence; Animals; Antibodies, Phospho-Specific; Cell Count; Cellular Structures; Chlorocebus aethiops; COS Cells; Microfilament Proteins; Molecular Sequence Data; Mutant Proteins; Mutation; Myocytes, Smooth Muscle; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C-alpha; Protein Structure, Tertiary; Protein Transport; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2008 |
Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization.
Topics: Actins; Amino Acid Sequence; Animals; Cell Nucleus; DNA-Binding Proteins; HeLa Cells; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Mutation; Oncogene Proteins, Fusion; Phosphorylation; Phosphoserine; Protein Binding; Protein Transport; Serum; Serum Response Factor; Tetradecanoylphorbol Acetate; Trans-Activators | 2008 |
Protein kinase C isoforms differentially phosphorylate Ca(v)1.2 alpha(1c).
Topics: Amino Acid Sequence; Animals; Calcium Channels, L-Type; Cell Line; Humans; In Vitro Techniques; Isoenzymes; Mice; Mice, Knockout; Molecular Sequence Data; Myocytes, Cardiac; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Structure, Secondary; Rabbits; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2009 |
Phosphorylation at S384 regulates the activity of the TaALMT1 malate transporter that underlies aluminum resistance in wheat.
Topics: Aluminum; Animals; Enzyme Inhibitors; Malates; Mutation; Oocytes; Organic Anion Transporters; Phosphoserine; Plant Proteins; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Triticum; Xenopus laevis | 2009 |
Protein phosphatase 1alpha associates with protein tyrosine phosphatase-PEST inducing dephosphorylation of phospho-serine 39.
Topics: Antibodies, Phospho-Specific; Blotting, Western; Catalytic Domain; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Mutant Proteins; Phosphorylation; Phosphoserine; Protein Interaction Domains and Motifs; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Two-Hybrid System Techniques | 2010 |
Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) functionally associates with PKCepsilon and VASP in the regulation of macrophage migration.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Adhesion Molecules; Cell Movement; HeLa Cells; Humans; Interleukin-1 Receptor-Associated Kinases; Macrophages; Mice; Mice, Inbred C57BL; Microfilament Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Binding; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate | 2010 |
Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains.
Topics: Amino Acid Sequence; Animals; Binding Sites; Class Ia Phosphatidylinositol 3-Kinase; Enzyme Activation; Enzyme Activators; HEK293 Cells; Humans; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Binding; Protein Kinase C; Protein Multimerization; Signal Transduction; src Homology Domains; Tetradecanoylphorbol Acetate; Time Factors | 2011 |
Identification of novel interaction between ADAM17 (a disintegrin and metalloprotease 17) and thioredoxin-1.
Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Sequence; Animals; Chromatography, Liquid; Cross-Linking Reagents; Enzyme Activation; HEK293 Cells; HeLa Cells; Heparin-binding EGF-like Growth Factor; Humans; Immunoblotting; Intercellular Signaling Peptides and Proteins; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Models, Molecular; Molecular Sequence Data; Phosphorylation; Phosphoserine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Recombinant Proteins; Reproducibility of Results; Tetradecanoylphorbol Acetate; Thioredoxins | 2012 |
Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cyclooxygenase 2; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Isoenzymes; Mice; Models, Biological; Muscle Proteins; Neoplasm Invasiveness; Neoplasms; NFATC Transcription Factors; Phosphorylation; Phosphoserine; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Response Elements; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2012 |
12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells.
Topics: Cell Line, Tumor; HEK293 Cells; Humans; Phosphorylation; Phosphoserine; Proteasome Endopeptidase Complex; Proteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin | 2013 |
Interleukin (IL)-32β-mediated CCAAT/enhancer-binding protein α (C/EBPα) phosphorylation by protein kinase Cδ (PKCδ) abrogates the inhibitory effect of C/EBPα on IL-10 production.
Topics: Base Sequence; CCAAT-Enhancer-Binding Protein-alpha; Enzyme Activation; HEK293 Cells; Humans; Interleukin-10; Interleukins; Molecular Sequence Data; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Protein Binding; Protein Interaction Mapping; Protein Kinase C-delta; Protein Structure, Tertiary; Protein Transport; Tetradecanoylphorbol Acetate; U937 Cells | 2013 |
Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size.
Topics: Animals; Cell Communication; Connexin 43; Dogs; Gap Junctions; Humans; Hypoxia; Ischemia; Madin Darby Canine Kidney Cells; Male; Mice; Myocardium; Phosphorylation; Phosphoserine; Proteasome Inhibitors; Protein Binding; Proto-Oncogene Proteins c-akt; Skin; Tetradecanoylphorbol Acetate; Zonula Occludens-1 Protein | 2014 |
Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody.
Topics: Animals; Antibodies, Phospho-Specific; Antibody Specificity; Cell Nucleus; Green Fluorescent Proteins; Humans; Interleukin-6; Lipopolysaccharides; Liver; Mice; Mitochondria; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Transport; Proto-Oncogene Proteins c-fos; Single-Chain Antibodies; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2014 |
IL-32θ downregulates CCL5 expression through its interaction with PKCδ and STAT3.
Topics: Cell Line; Chemokine CCL5; Down-Regulation; Humans; Interleukins; Oligonucleotide Array Sequence Analysis; Phosphorylation; Phosphoserine; Promoter Regions, Genetic; Protein Binding; Protein Kinase C-delta; RNA, Messenger; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2014 |
PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells.
Topics: Bronchoconstrictor Agents; Calcium; Cells, Cultured; Cytosol; Enzyme Activation; Histamine; Humans; Ion Channel Gating; KCNQ Potassium Channels; Membrane Potentials; Myocytes, Smooth Muscle; Phosphorylation; Phosphoserine; Protein Kinase C; Tetradecanoylphorbol Acetate; Trachea | 2017 |
Prenatal hypoxia attenuated contraction of offspring coronary artery associated with decreased PKCβ Ser
Topics: Animals; Body Weight; Calcium; Calcium Channels; Coronary Vessels; Endoplasmic Reticulum; Female; Hypoxia; Intracellular Space; Myocardium; Organ Size; Phosphorylation; Phosphoserine; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C beta; Rats, Sprague-Dawley; Serotonin; Tetradecanoylphorbol Acetate; Vasoconstriction | 2020 |
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Cell Line; Fibroblasts; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Knockout; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; rab GTP-Binding Proteins; Recombinant Proteins; RNA, Small Interfering; Sequence Alignment; Sequence Homology, Amino Acid; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 2021 |