tetradecanoylphorbol acetate has been researched along with phenylephrine in 128 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (25.78) | 18.7374 |
| 1990's | 59 (46.09) | 18.2507 |
| 2000's | 33 (25.78) | 29.6817 |
| 2010's | 3 (2.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatch, GE; Hill, HR; Nichols, WK | 1 |
| Castagna, M; Rochette-Egly, C | 1 |
| Dettmer, D; Hermsdorf, T | 1 |
| Garcia-Ruiz, C; Kaplowitz, N; Kuhlenkamp, J; Lu, SC | 1 |
| Hreniuk, S; LaNoue, KF; Scaduto, RC; Sterniczuk, A | 1 |
| Altschuld, RA; Hohl, CM; Hu, B | 1 |
| Chik, CL; Ho, AK | 2 |
| Higashi, K; Hoek, JB | 1 |
| Demigne, C; Morand, C; Redon, C; Remesy, C | 1 |
| Endou, M; Hattori, Y; Kanno, M; Nakaya, H; Tohse, N | 1 |
| Chik, CL; Cragoe, EJ; Ho, AK; Lalh, SS; Young, I | 1 |
| Conricode, KM; Ochs, RS | 1 |
| Hisayama, T; Huang, XN; Takanayagi, I | 1 |
| Klein, DC; Sugden, D | 1 |
| Molderings, GJ; Schümann, HJ | 1 |
| Glembotski, CC; Shields, PP | 1 |
| Chik, CL; Ho, AK; Klein, DC | 1 |
| Kamata, K; Nakanishi, T; Nojima, K; Seguchi, M; Takao, A | 1 |
| Akerman, KE; Enkvist, MO; Holopainen, I | 2 |
| Chik, CL; Cragoe, EJ; Ho, AK; Klein, DC; Weller, JL | 1 |
| Ayuso, MS; González-Manchón, C; Parrilla, R; Saz, JM | 1 |
| Deaciuc, IV; Hermiller, JB; Mehegan, JP; Rodriguez de Turco, EB; Roth, BL; Spitzer, JA | 1 |
| Lim, AT; Vale, W; Widmaier, EP | 1 |
| Azhar, S; Hoffman, BB; Rosenbaum, JS | 1 |
| Aloyo, VJ; Walker, RF | 1 |
| Eipper, BA; May, V; Wand, GS | 1 |
| Ho, AK; Klein, DC; Sugden, AL; Sugden, D | 1 |
| Hartmann, HA; Houser, SR; Kleiman, RB; Mazzocca, NJ | 1 |
| Ho, AK; Klein, DC | 1 |
| Klein, DC; Sugden, D; Vanecek, J; Weller, JL | 1 |
| Dzierzanowski, D; Elliott, ME; Honeyman, TW; Schimmel, RJ | 1 |
| Hoek, JB; Rubin, R; Thomas, AP | 1 |
| Schimmel, RJ | 1 |
| Khalil, RA; van Breemen, C | 1 |
| Jiang, MJ; Morgan, KG | 1 |
| Cobbold, PH; Cuthbertson, KS; Woods, NM | 1 |
| Cooper, DR; Davis, JS; Farese, RV; Konda, TS; Pollet, RJ; Standaert, ML | 1 |
| Patel, TB | 1 |
| Hansford, RG; Staddon, JM | 1 |
| Rao, KM | 1 |
| Danthuluri, NR; Deth, RC | 2 |
| Coll, KE; Cooper, RH; Williamson, JR | 1 |
| Carrière, S; Chan, JS; Delalandre, A; Lachance, S; Wang, TT | 1 |
| Hatake, K; Sakamoto, K; Wakabayashi, I | 1 |
| Bogoyevitch, MA; Marshall, CJ; Sugden, PH | 1 |
| Itoh, H; Kishimoto, I; Komatsu, Y; Nakagawa, O; Nakao, K; Nishino, K; Ogawa, Y; Suga, S; Yoshimasa, T | 1 |
| Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y | 2 |
| Biden, TJ; Browne, CL; Darby, K; Herzog, H; Schmitz-Peiffer, C; Selbie, LA; Shine, J | 1 |
| Bhatti, T; Han, C; Ito, K; Ramwell, PW; Thomas, G; Zikic, E | 1 |
| Dartt, DA; Zoukhri, D | 1 |
| Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y | 1 |
| Karpinski, E; Liu, QY; Pang, PK | 1 |
| Grohé, C; Maass, A; Neyses, L; Oberdorf, S; Sukhatme, VP; Vetter, H | 1 |
| Frost, JA; Thorburn, A; Thorburn, J | 1 |
| Hagino, Y; Hasegawa, S; Kondo, H; Nomura, H; Nomura, T; Sumi-Ichinose, C; Tachibana, M; Ukai, K; Watanabe, T; Yokoyama, R | 1 |
| Conde, M; Gualberto, A; Sobrino, F | 1 |
| Bogoyevitch, MA; Glennon, PE; Sugden, PH | 1 |
| Hoffman, BB; Hu, ZW; Sakaue, M; Shi, XY | 1 |
| Bezstarosti, K; Dekkers, DH; Lamers, JM; Van Heugten, HA | 1 |
| Anwer, MS; Engelking, LR; Grüne, S | 1 |
| Major, TC; Overhiser, RW; Panek, RL; Taylor, DG | 1 |
| Askari, A; Huang, L; Huang, WH; Peng, M; Xie, ZJ | 1 |
| Kitada, Y | 1 |
| Abe-Dohmae, S; Harada, N; Takagi, Y | 1 |
| Packer, CS; Rhoades, RA; Zhao, Y | 1 |
| Tseng, GN; Tseng-Crank, J; Yao, JA | 1 |
| Davies, EL; Fuller, SJ; Gillespie-Brown, J; Sun, H; Tonks, NK | 1 |
| Clerk, A; Sugden, PH | 2 |
| Bezstarosti, K; Dekkers, DH; Eskildsen-Helmond, YE; Lamers, JM; van Heugten, HA | 1 |
| Chik, CL; Ho, AK; Negishi, T | 1 |
| Kimura, M; Ogihara, M | 3 |
| Clerk, A; Lazou, A; Sugden, PH | 1 |
| Büscher, R; Grübbel, B; Insel, PA; Michel, MC; Taguchi, K; Yang, M | 1 |
| Carmeliet, E; Flameng, W; Mubagwa, K; Stengl, M | 1 |
| Clemow, DB; McCarty, R; Steers, WD; Tuttle, JB | 1 |
| Björnsson, OG; Bourgeois, CS; Gibbons, GF | 1 |
| Emala, CW; Hirshman, CA; Kuhl, JS; Levitsky, HI; Lindeman, KS | 1 |
| Lee, CO; Woo, SH | 1 |
| Montessuit, C; Thorburn, A | 1 |
| Hama, J; Hidaka, H; Horiuchi, M; Ishikawa, K; Kamoi, K; Katori, R; Kondo, H; Kurroka, A; Shimada, S; Watanabe, M; Yamamoto, Y | 1 |
| Piper, HM; Schäfer, M; Schlüter, KD; Simm, A; Taimor, G | 1 |
| Chiloeches, A; Clerk, A; Marais, R; Marshall, CJ; Paterson, HF; Sugden, PH | 1 |
| Hayasaki-Kajiwara, Y; Iwaki, K; Iwasaki, T; Kitano, Y; Nakajima, M; Naya, N; Shimamura, T | 1 |
| Alexandrov, A; Goepel, M; Keffel, S; Michel, MC | 1 |
| Michel, MC; Ruan, J; Schalken, J; Voller, M; Yang, M | 1 |
| Bednarczyk, D; Dantzler, WH; Gekle, M; Mildenberger, S; Sauvant, C; Wright, SH | 1 |
| Brunner, HR; Domenighetti, A; Marsh, DJ; Palmiter, RD; Pedrazzini, T; Pellieux, C; Sauthier, T | 1 |
| Ballou, LM; Cross, ME; Lin, RZ; McReynolds, EM; Rybkin, II | 1 |
| Chan, W; Huang, Y; Ko, W; Yao, X | 1 |
| Cattini, PA; Detillieux, KA; Jin, Y; Sheikh, F | 1 |
| Avkiran, M; Goss, MW; Haworth, RS; Rozengurt, E | 1 |
| Heller, J; Lebrec, D; Moreau, R; Poirel, O; Tazi, KA | 1 |
| Chae, SW; Cho, CH; Jo, SH; Lee, CO | 1 |
| Hofmann, PA; Lester, JW | 1 |
| Carrière, S; Chan, JS; Chen, X; Wang, TT; Zhang, SL | 1 |
| Leite, R; Webb, RC | 1 |
| Harada, N; Nakaya, Y; Niwa, Y; Sakamoto, S | 1 |
| Bell, JR; Eaton, P; Fuller, W; Shattock, MJ | 1 |
| Altavilla, D; Bazzani, C; Bertolini, A; Galeano, M; Guarini, S; Saitta, A; Santamaria, LB; Squadrito, F; Squadrito, G; Venuti, FS | 1 |
| Buttrick, PM; Del Nido, P; Dowell, JC; Koretsky, AP; Montgomery, DE; Pyle, WG; Roman, BB; Solaro, RJ; Wolska, BM | 1 |
| Barton, PJ; Clerk, A; Harrison, JG; Kemp, TJ; Mullen, AJ; Sugden, PH | 1 |
| Aass, H; Andersen, GØ; Osnes, JB; Qvigstad, E; Schiander, I; Skomedal, T | 1 |
| Cramer, R; Fenton, T; Filonenko, V; Gout, IT; Gzhegotsky, M; Lutsyk, A; Matsuka, G; Parker, PJ; Proud, CG; Rebholz, H; Valovka, T; Verdier, F; Wang, L; Wang, ML; Zhyvoloup, A | 1 |
| Dartt, DA; Hodges, RR; Tepavcevic, V; Zoukhri, D | 1 |
| Izumo, S; Ma, Q; Pu, WT | 1 |
| Bayer, AL; Byron, KL; Heidkamp, MC; Heller Brown, J; Howes, AL; Samarel, AM | 1 |
| Bourgoin, SG; Gandhi, GK; Malik, KU; Parmentier, JH; Saeed, AE; Wiggins, MT | 1 |
| Husain, S; Wingard, CJ; Young, D | 1 |
| Galiñanes, M; Hassouna, A; Loubani, M | 1 |
| Chatsudthipong, V; Dantzler, WH; Evans, KK; Soodvilai, S; Wright, SH | 1 |
| Bengtsson, T; Hutchinson, DS | 1 |
| Iwata, Y; Katanosaka, Y; Kobayashi, Y; Shibasaki, F; Shigekawa, M; Wakabayashi, S | 1 |
| Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB | 1 |
| El-Armouche, A; Eschenhagen, T; Grimm, M; Haas, P; Mahnecke, N; Reichenspurner, H; Soja, F; Treede, H | 1 |
| Dartt, DA; Hodges, RR; Ota, I; Rios, JD; Vrouvlianis, J; Zoukhri, D | 1 |
| Abe, K; Nishiura, T | 1 |
| Ding, WG; Horie, M; Ito, M; Matsuura, H; Toda, H; Toyoda, F; Yasuda, Y | 1 |
| Crouch, NR; Ferrara, A; Fusi, F; Koorbanally, C; Mulholland, DA; Sgaragli, G | 1 |
| Bian, JS; Chen, J; Chen, K; McDonald, TV; Sroubek, J; Thomas, D; Wu, ZY | 1 |
| Kimura, M; Moteki, H; Ogihara, M | 1 |
| Kimura, M; Moteki, H; Ogihara, M; Sunaga, K; Tsuda, T | 1 |
2 review(s) available for tetradecanoylphorbol acetate and phenylephrine
| Article | Year |
|---|---|
Catecholamines and angiotensinogen gene expression in kidney proximal tubular cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensinogen; Animals; Cell Line; Clonidine; Gene Expression Regulation; Human Growth Hormone; Humans; Isoproterenol; Kidney Tubules, Proximal; Norepinephrine; Opossums; Phenylephrine; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2000 |
Activation of the small GTP-binding protein Ras in the heart by hypertrophic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Cardiomegaly; Endothelin-1; Heart; Humans; Monomeric GTP-Binding Proteins; Myocardium; Phenylephrine; Protein Binding; ras Proteins; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 2000 |
126 other study(ies) available for tetradecanoylphorbol acetate and phenylephrine
| Article | Year |
|---|---|
Cyclic nucleotide changes in human neutrophils induced by chemoattractants and chemotactic modulators.
Topics: Carbachol; Chemotaxis, Leukocyte; Complement System Proteins; Cyclic AMP; Cyclic GMP; Dipeptides; Drug Synergism; Escherichia coli; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Neutrophils; Phenylephrine; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate | 1977 |
A tumor-promoting phorbol ester inhibits the cyclic AMP response of rat embryo fibroblasts to catecholamines and prostaglandin E1.
Topics: Animals; Catecholamines; Cyclic AMP; Embryo, Mammalian; Female; Fibroblasts; In Vitro Techniques; Phenylephrine; Phorbol Esters; Phorbols; Pregnancy; Prostaglandins E; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Phorbol ester effects on hormonal responses in freshly isolated short-term incubated and cultured hepatocytes.
Topics: Animals; Glucagon; Glucose; In Vitro Techniques; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.
Topics: Animals; Bucladesine; Cells, Cultured; Cytosol; Down-Regulation; Glucagon; Glutathione; In Vitro Techniques; Liver; Male; Perfusion; Phenylephrine; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
The mechanism of Ca2(+)-related control of gluconeogenesis in perfused liver.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Glucagon; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Phenylephrine; Rats; Tetradecanoylphorbol Acetate | 1991 |
Phorbol esters and cyclic AMP activate AMP deaminase in adult rat cardiac myocytes.
Topics: Adrenergic alpha-Agonists; Alkaloids; AMP Deaminase; Animals; Cyclic AMP; Enzyme Activation; Epinephrine; Inosine Monophosphate; Kinetics; Myocardium; Phenylephrine; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
See-saw signal processing: reciprocal effects of stimulus deprivation on vasoactive intestinal peptide-stimulated adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation in rat pinealocytes.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Light; Male; Phenylephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Sensory Deprivation; Signal Transduction; Sympathomimetics; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1991 |
Ethanol causes desensitization of receptor-mediated phospholipase C activation in isolated hepatocytes.
Topics: Angiotensin II; Animals; Calcium; Enzyme Activation; Epidermal Growth Factor; Ethanol; Glucagon; Liver; Male; Phenylephrine; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasopressins | 1991 |
Non-hormonal and hormonal control of glycogen metabolism in isolated sheep liver cells.
Topics: Animals; Drug Interactions; Egtazic Acid; Enzyme Activation; Epinephrine; Fructose; Glucagon; Glucose; Glycogen; Glycogen Synthase; Insulin; Liver; Phenylephrine; Phosphorylase a; Propionates; Sheep; Tetradecanoylphorbol Acetate | 1990 |
Inhibitory effect mediated by alpha 1-adrenoceptors on transient outward current in isolated rat ventricular cells.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Cell Separation; Electrophysiology; Heart Ventricles; Kinetics; Myocardial Contraction; Myocardium; Phenylephrine; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Inhibitory effects of amilorides on pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation: possible involvement of postreceptor mechanisms.
Topics: Amiloride; Animals; Carrier Proteins; Cyclic AMP; Cyclic GMP; Drug Synergism; Hydrogen-Ion Concentration; Isoproterenol; Male; Norepinephrine; Phenylephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1990 |
Epidermal growth factor and 12-O-tetradecanoylphorbol 13-acetate stimulate lactate production and the pentose phosphate pathway in freshly isolated rat hepatocytes.
Topics: Animals; Bucladesine; Cells, Cultured; Epidermal Growth Factor; Glycolysis; Insulin; Kinetics; Lactates; Liver; Male; Pentose Phosphate Pathway; Phenylephrine; Pyruvates; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Endothelin-1 induced contraction of rat aorta in Ca2(+)-free medium independent of phosphatidylinositol 4,5-bisphosphate (PIP2) breakdown.
Topics: Animals; Aorta, Thoracic; Calcium; Culture Media; Endothelins; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Phenylephrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Activators of protein kinase C act at a postreceptor site to amplify cyclic AMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Phenylephrine; Phorbol Esters; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1988 |
Amplifying effects of several vasoconstrictor agents of alpha 1-adrenoceptor-mediated contraction of isolated thoracic aortae of the guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Azepines; Dose-Response Relationship, Drug; Endothelium; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Ouabain; Phenylephrine; Receptors, Adrenergic, alpha; Serotonin; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1989 |
Regulation of atrial natriuretic factor-(99-126) secretion from neonatal rat primary atrial cultures by activators of protein kinases A and C.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Enzyme Activation; Heart Atria; Peptide Fragments; Phenylephrine; Prazosin; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Forskolin stimulates pinealocyte cGMP accumulation. Dramatic potentiation by an alpha 1-adrenergic----[Ca2+]i mechanism involving protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cations, Divalent; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Female; Phenylephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Inotropic effect of phenylephrine and myocardial alpha-adrenergic receptor in newborn and adult animals.
Topics: Animals; Animals, Newborn; Dogs; Enzyme Activation; Heart; Myocardial Contraction; Phenylephrine; Propranolol; Protein Kinase C; Rabbits; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Species Specificity; Tetradecanoylphorbol Acetate | 1989 |
Alpha-receptor and cholinergic receptor-linked changes in cytosolic Ca2+ and membrane potential in primary rat astrocytes.
Topics: Animals; Astrocytes; Calcium; Carbachol; Cells, Cultured; Membrane Potentials; Phenylephrine; Potassium Channels; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Tetradecanoylphorbol Acetate; Valinomycin | 1989 |
Evidence of alpha 1-adrenergic----protein kinase C----Na+/H+ antiporter-dependent increase in pinealocyte intracellular pH. Role in the adrenergic stimulation of cGMP accumulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amiloride; Animals; Calcium; Carrier Proteins; Cyclic AMP; Cyclic GMP; Cytosol; Enzyme Activation; Hydrogen-Ion Concentration; Norepinephrine; Phenylephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Receptors, Adrenergic, alpha; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1989 |
Effect of cellular Ca2+ loading on alpha 1-agonist or protein kinase C activators-mediated stimulation of phosphorylase "a" in liver cells.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Diglycerides; Enzyme Activation; Fatty Acids, Unsaturated; Liver; Male; Oleic Acid; Oleic Acids; Oxidation-Reduction; Phenylephrine; Phosphorylase a; Phosphorylases; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1989 |
Modification of protein kinase C (PKC) activity and diacylglycerol (DAG) accumulation in hepatocytes in continuous endotoxemia.
Topics: Animals; Biological Transport; Cytosol; Diglycerides; Endotoxins; Glycerides; Kinetics; Liver; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1989 |
Secretion of corticotropin-releasing factor from cultured rat hypothalamic cells: effects of catecholamines.
Topics: Animals; Animals, Newborn; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Hypothalamus; Isoproterenol; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Alpha 1 adrenergic receptor mediated polyphosphoinositide breakdown in DDT1-MF2 cells. Lack of evidence of desensitization after prolonged exposure to epinephrine.
Topics: Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Inositol Phosphates; Isoproterenol; Muscle, Smooth; Phenylephrine; Phosphatidylinositols; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1987 |
Molecular mechanisms controlling norepinephrine-mediated release of serotonin from rat pineal glands.
Topics: Animals; Isoproterenol; Kinetics; Norepinephrine; Phentolamine; Phenylephrine; Pineal Gland; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Serotonin; Sotalol; Tetradecanoylphorbol Acetate | 1987 |
Comparison of acute and chronic secretagogue regulation of proadrenocorticotropin/endorphin synthesis, secretion, and messenger ribonucleic acid production in primary cultures of rat anterior pituitary.
Topics: Adrenocorticotropic Hormone; Animals; beta-Lipotropin; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Endorphins; Immunosorbent Techniques; Male; Phenylephrine; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Negative feedback mechanisms: evidence that desensitization of pineal alpha 1-adrenergic responses involves protein kinase-C.
Topics: Animals; Arylamine N-Acetyltransferase; Calcium; Cells, Cultured; Cyclic AMP; Cyclic GMP; Feedback; Female; Kinetics; Norepinephrine; Phenylephrine; Phosphatidylinositols; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1988 |
Effects of phenylephrine on calcium current and contractility of feline ventricular myocytes.
Topics: Animals; Calcium Channels; Cats; Egtazic Acid; Electric Conductivity; Electrophysiology; Myocardial Contraction; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1988 |
Activation of alpha 1-adrenoceptors, protein kinase C, or treatment with intracellular free Ca2+ elevating agents increases pineal phospholipase A2 activity. Evidence that protein kinase C may participate in Ca2+-dependent alpha 1-adrenergic stimulation o
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Calcium; Diglycerides; Lysophosphatidylcholines; Male; Norepinephrine; Organ Culture Techniques; Ouabain; Ovariectomy; Phenylephrine; Phospholipases; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinase C; Quinacrine; Rats; Tetradecanoylphorbol Acetate | 1987 |
See-saw signal processing in pinealocytes involves reciprocal changes in the alpha 1-adrenergic component of the cyclic GMP response and the beta-adrenergic component of the cyclic AMP response.
Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Isoproterenol; Kinetics; Light; Male; Nitroprusside; Norepinephrine; Periodicity; Phenylephrine; Pineal Gland; Quinacrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1986 |
Stimulation of phosphoinositide metabolism in hamster brown adipocytes exposed to alpha 1-adrenergic agents and its inhibition with phorbol esters.
Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue, Brown; Animals; Cricetinae; In Vitro Techniques; Insulin; Isoproterenol; Male; Mesocricetus; Oxygen Consumption; Phenylephrine; Phosphatidylinositols; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Ethanol-induced phospholipase C activation is inhibited by phorbol esters in isolated hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcimycin; Diglycerides; Enzyme Activation; Ethanol; Fluorescent Dyes; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
The alpha 1-adrenergic transduction system in hamster brown adipocytes. Release of arachidonic acid accompanies activation of phospholipase C.
Topics: Adipose Tissue, Brown; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Colforsin; Cricetinae; Cyclohexanones; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Inositol Phosphates; Insulin; Isoproterenol; Lipid Metabolism; Male; Phenylephrine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Activators of protein kinase C and phenylephrine depolarize the astrocyte membrane by reducing the K+ permeability.
Topics: Animals; Astrocytes; Cells, Cultured; Diglycerides; Dithiazanine; Phenylephrine; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Sustained contraction of vascular smooth muscle: calcium influx or C-kinase activation?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Potassium; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1988 |
Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle.
Topics: Animals; Aorta; Calcium; Ferrets; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes.
Topics: Aequorin; Animals; Arginine Vasopressin; Biological Transport; Calcium; In Vitro Techniques; Liver; Male; Phenylephrine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes.
Topics: Animals; Cell Line; Cell Membrane; Cytosol; Insulin; Kinetics; Mice; Muscles; Phenylephrine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of hepatic glycogenolysis by phorbol 12-myristate 13-acetate.
Topics: Animals; Calcium; Diglycerides; Glucose; Liver; Liver Glycogen; Male; Oxygen Consumption; Phenylephrine; Prostaglandins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
The glucagon-induced activation of pyruvate dehydrogenase in hepatocytes is diminished by 4 beta-phorbol 12-myristate 13-acetate. A role for cytoplasmic Ca2+ in dehydrogenase regulation.
Topics: Animals; Arginine Vasopressin; Calcium; Cytoplasm; Enzyme Activation; Glucagon; In Vitro Techniques; Liver; Male; NADP; Phenylephrine; Pyruvate Dehydrogenase Complex; Pyruvate Kinase; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Age-related decline in ligand-induced actin polymerization in human leukocytes and platelets.
Topics: Actins; Adult; Aged; Aging; Blood Platelets; Female; Humans; In Vitro Techniques; Ligands; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylephrine; Tetradecanoylphorbol Acetate; Triiodothyronine | 1986 |
Acute desensitization to angiotensin II: evidence for a requirement of agonist-induced diacylglycerol production during tonic contraction of rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Diglycerides; Enzyme Activation; Glycerides; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1986 |
Differential effects of phorbol ester on phenylephrine and vasopressin-induced Ca2+ mobilization in isolated hepatocytes.
Topics: Aminoquinolines; Animals; Calcimycin; Calcium; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Ethers; Ionomycin; Liver; Male; Phenylephrine; Phorbols; Phosphorylases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Phorbol ester-induced contraction of arterial smooth muscle and inhibition of alpha-adrenergic response.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Phorbols; Rabbits; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1984 |
Alpha-adrenoceptors and angiotensinogen gene expression in opossum kidney cells.
Topics: Adrenergic alpha-Agonists; Affinity Labels; Alkaloids; Angiotensinogen; Animals; Cells, Cultured; Clonidine; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Kidney Tubules; Opossums; Phenylephrine; Prazosin; Protein Kinase C; Receptors, Adrenergic, alpha; Staurosporine; Tetradecanoylphorbol Acetate; Yohimbine | 1995 |
Inhibitory effects of cadmium ion on extracellular Ca(2+)-independent contraction of rat aorta.
Topics: Animals; Aorta, Thoracic; Cadmium; Calcium; Ethers, Cyclic; Extracellular Space; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Okadaic Acid; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Sodium Fluoride; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1995 |
Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes.
Topics: Animals; Animals, Newborn; Brain; Carbachol; Cells, Cultured; Culture Media; Cyclic AMP; Endothelins; Enzyme Activation; Fibroblast Growth Factor 1; Gene Expression; Growth Substances; Heart Ventricles; Isoenzymes; Kinetics; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Myocardium; Pertussis Toxin; Phenylephrine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1995 |
Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA Primers; Endothelins; Enzyme Activation; Gene Expression Regulation; Heart Ventricles; Kinetics; Molecular Sequence Data; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phenylephrine; Protein Kinase C; Radioimmunoassay; Rats; Rats, Wistar; Restriction Mapping; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Differential effects of putative protein kinase C inhibitors on contraction of rat aortic smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta; Dose-Response Relationship, Drug; Isoquinolines; Male; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Phorbol 12,13-Dibutyrate; Piperazines; Polycyclic Compounds; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction | 1993 |
Pituitary adenylate cyclase-activating polypeptide: control of rat pineal cyclic AMP and melatonin but not cyclic GMP.
Topics: Animals; Cyclic AMP; Cyclic GMP; Drug Synergism; Male; Melatonin; Neuropeptides; Phenylephrine; Pineal Gland; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1995 |
Synergistic interaction of Y1-neuropeptide Y and alpha 1b-adrenergic receptors in the regulation of phospholipase C, protein kinase C, and arachidonic acid production.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Arachidonic Acid; Calcium; CHO Cells; Cricetinae; Drug Synergism; Enzyme Activation; Hydroquinones; Inositol 1,4,5-Trisphosphate; Peptide YY; Peptides; Pertussis Toxin; Phenylephrine; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Protein Kinase C; Receptors, Adrenergic, alpha-1; Receptors, Neuropeptide Y; Recombinant Fusion Proteins; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 1995 |
Specific inhibition of the contraction of the rat aorta by estradiol 17 beta.
Topics: Animals; Aorta; Cyclooxygenase Inhibitors; Estradiol; In Vitro Techniques; Male; Microscopy, Electron; Muscle Contraction; Nitric Oxide; Phenylephrine; Potassium Chloride; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
Cholinergic activation of phospholipase D in lacrimal gland acini is independent of protein kinase C and calcium.
Topics: Animals; Atropine; Calcium; Carbachol; Diacylglycerol Kinase; Enzyme Activation; Epinephrine; Ethanol; Lacrimal Apparatus; Male; Phenylephrine; Phosphatidic Acids; Phosphatidylethanolamines; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Rats, Wistar; Receptors, Cholinergic; Stearic Acids; Tetradecanoylphorbol Acetate | 1995 |
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
L-channel modulation by alpha-1 adrenoceptor activation in neonatal rat ventricular cells: intracellular mechanisms.
Topics: Animals; Animals, Newborn; Calcium Channels; Cholera Toxin; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Pertussis Toxin; Phenylephrine; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
Mitogenic signals control translation of the early growth response gene-1 in myogenic cells.
Topics: Angiotensin II; Animals; Base Sequence; Becaplermin; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelins; Fibroblast Growth Factor 2; Immediate-Early Proteins; Insulin; Mice; Molecular Sequence Data; Muscles; Oligodeoxyribonucleotides; Phenylephrine; Platelet-Derived Growth Factor; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Zinc Fingers | 1994 |
Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy.
Topics: Actins; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytoskeleton; Enzyme Activation; Gene Expression Regulation; Hypertrophy; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Mutation; Myocardium; Phenotype; Phenylephrine; Rats; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Alpha 1B-adrenoceptor-mediated stimulation of Ca2+ mobilization and cAMP accumulation in isolated rat hepatocytes.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; Cyclic AMP; Dioxanes; In Vitro Techniques; Liver; Male; Methoxamine; Norepinephrine; Pertussis Toxin; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins; Virulence Factors, Bordetella | 1993 |
Cyclosporin A antagonizes phenylephrine, oxytocin and angiotensin effects on glucose metabolism in rat thymus lymphocytes.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Cyclosporine; Dose-Response Relationship, Drug; Fructosediphosphates; Glucose; Glycolysis; Lactates; Lactic Acid; Lymphocytes; Male; Oxytocin; Phenylephrine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland | 1994 |
Endothelin-1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Chromatography, Liquid; Disease Models, Animal; Endothelins; Enzyme Activation; Glycogen Synthase Kinase 3; Molecular Sequence Data; Myocardium; Phenylephrine; Phosphoprotein Phosphatases; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1993 |
Prolonged activation of protein kinase C induces transcription and expression of the alpha 1B adrenergic receptor gene in DDT1 MF-2 cells.
Topics: Animals; Cell Nucleus; Cricetinae; Enzyme Activation; Gene Expression Regulation, Neoplastic; Inositol 1,4,5-Trisphosphate; Kinetics; Mesocricetus; Phenylephrine; Protein Kinase C; Receptors, Adrenergic, alpha; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Homologous desensitization of the endothelin-1 receptor mediated phosphoinositide response in cultured neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; Endothelins; Inositol Phosphates; Myocardium; Phenylephrine; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Wistar; Receptors, Endothelin; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Role of intracellular calcium and protein kinases in the activation of hepatic Na+/taurocholate cotransport by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Colforsin; Cyclic AMP; Ionomycin; Kinetics; Liver; Phenylephrine; Protein Kinase Inhibitors; Protein Kinases; Rats; Sodium; Taurocholic Acid; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1993 |
Effects of quinapril, a new angiotensin-converting enzyme inhibitor, on vasoconstrictor activity in the isolated, perfused mesenteric vasculature of hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Hypertension; In Vitro Techniques; Isoquinolines; Male; Mesenteric Arteries; Phenylephrine; Potassium Chloride; Quinapril; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Vasoconstriction | 1993 |
Oxidant-induced activations of nuclear factor-kappa B and activator protein-1 in cardiac myocytes.
Topics: Animals; Animals, Newborn; Antioxidants; Gene Expression Regulation; Genes, fos; Genes, jun; Heart; Hydrogen Peroxide; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Oxidants; Oxidative Stress; Phenylephrine; Pyrrolidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiocarbamates; Transcription Factor AP-1 | 1995 |
MCI-154-induced relaxation in vascular smooth muscles of guinea pig.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Endothelium, Vascular; Femoral Artery; Guinea Pigs; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Pyridazines; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Neurotransmitter-mediated regulation of brain aromatase: protein kinase C- and G-dependent induction.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Aromatase; Brain; Bucladesine; Cells, Cultured; Cholecystokinin; Diencephalon; Embryonic and Fetal Development; Enzyme Induction; Female; Fetus; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; GTP-Binding Proteins; Mice; Mice, Inbred ICR; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; Neuropeptides; Neurotensin; Neurotransmitter Agents; Phenylephrine; Prazosin; Pregnancy; Protein Kinase C; Receptors, Adrenergic, alpha-1; RNA, Messenger; Signal Transduction; Substance P; Tetradecanoylphorbol Acetate | 1996 |
Hypoxia-induced pulmonary arterial contraction appears to be dependent on myosin light chain phosphorylation.
Topics: Angiotensin II; Animals; Azepines; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Naphthalenes; Phenylephrine; Phosphorylation; Potassium Chloride; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Modulation of K channels by coexpressed human alpha1C-adrenoceptor in Xenopus oocytes.
Topics: Animals; Female; Humans; Kinetics; Membrane Potentials; Oocytes; Phenylephrine; Phorbol Esters; Potassium Channels; Receptors, Adrenergic, alpha-1; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Xenopus laevis | 1997 |
Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes.
Topics: Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Endothelin-1; Gene Expression Regulation; Genes, Reporter; Immediate-Early Proteins; Luciferases; Mitogen-Activated Protein Kinase 1; Myocardium; Phenylephrine; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Sarcomeres; Tetradecanoylphorbol Acetate | 1997 |
Regulation of phospholipases C and D in rat ventricular myocytes: stimulation by endothelin-1, bradykinin and phenylephrine.
Topics: Adrenergic alpha-Agonists; Animals; Bradykinin; Cells, Cultured; Endothelin-1; Heart Ventricles; Hydrolysis; Phenylephrine; Phosphatidylinositols; Phospholipase D; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Cross-talk between receptor-mediated phospholipase C-beta and D via protein kinase C as intracellular signal possibly leading to hypertrophy in serum-free cultured cardiomyocytes.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Culture Media, Serum-Free; Down-Regulation; Endothelin-1; Histones; Immunoblotting; Isoenzymes; Myocardium; Phenylephrine; Phospholipase C beta; Phospholipase D; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Proliferation of adult rat hepatocytes in primary cultures induced by platelet-derived growth factor is potentiated by phenylephrine.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Division; Cells, Cultured; DNA Replication; Drug Synergism; Enzyme Inhibitors; Estrenes; Ionomycin; Liver; Male; Phenylephrine; Platelet-Derived Growth Factor; Pyrrolidinones; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Suramin; Tetradecanoylphorbol Acetate | 1998 |
Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart.
Topics: Adrenergic alpha-Agonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Heart; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Reperfusion; Tetradecanoylphorbol Acetate | 1998 |
Protein kinase C does not mediate phenylephrine-induced down-regulation of Madin-Darby canine kidney cell alpha-1B adrenoceptors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; beta-Adrenergic Receptor Kinases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dogs; Down-Regulation; G-Protein-Coupled Receptor Kinase 3; Indomethacin; Phenylephrine; Prazosin; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 1998 |
Phenylephrine-induced stimulation of Na+/Ca2+ exchange in rat ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Enzyme Inhibitors; Myocardium; Neomycin; Ouabain; Patch-Clamp Techniques; Phenanthridines; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Sodium-Calcium Exchanger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Effects of insulin-like growth factor I and II on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Topics: Animals; Brimonidine Tartrate; Cell Count; Cell Division; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Drug Interactions; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Isoquinolines; Liver; Male; Metaproterenol; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding.
Topics: Animals; Cells, Cultured; Colforsin; Hypertension; Isoproterenol; Nerve Growth Factors; Neuronal Plasticity; Neuropeptide Y; Phenylephrine; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Tetradecanoylphorbol Acetate; Urinary Bladder; Urination; Urination Disorders | 1998 |
Varying very low-density lipoprotein secretion of rat hepatocytes by altering cellular levels of calcium and the activity of protein kinase C.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cholesterol; Culture Media; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Ketone Bodies; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Phenanthridines; Phenylephrine; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Role of PKC in the effects of alpha1-adrenergic stimulation on Ca2+ transients, contraction and Ca2+ current in guinea-pig ventricular myocytes.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Electric Conductivity; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Ventricles; Myocardial Contraction; Phenylephrine; Prazosin; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Ventricular Function | 1999 |
Transcriptional activation of the glucose transporter GLUT1 in ventricular cardiac myocytes by hypertrophic agonists.
Topics: Animals; Cardiomegaly; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Dual Specificity Phosphatase 6; Flavonoids; Gene Expression Regulation; Genes, ras; Genes, Reporter; Glucose Transporter Type 1; Glucose Transporter Type 4; Heart Ventricles; Immediate-Early Proteins; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Muscle Proteins; Phenylephrine; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 1999 |
Alpha1-adrenergic stimulation induced hypertrophy in protein kinase C down-regulated cultured cardiac myocytes.
Topics: Adrenergic alpha-Agonists; Animals; Cardiomegaly; Cell Size; Cells, Cultured; Down-Regulation; Hypertrophy; Myocardium; Phenylephrine; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbon Radioisotopes; Carcinogens; Cardiomegaly; Cells, Cultured; Chromones; Creatine Kinase; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Heart Ventricles; Indoles; Isoenzymes; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle Fibers, Skeletal; Myocardium; Phenylephrine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Wortmannin | 1999 |
Regulation of Ras.GTP loading and Ras-Raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester. Activation of the extracellular signal-regulated kinase cascade by phorbol ester is mediated by Ras.
Topics: Animals; Cells, Cultured; Cyclic AMP; Down-Regulation; Endothelin-1; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Pertussis Toxin; Phenylephrine; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Na(+)influx via Na(+)/H(+)exchange activates protein kinase C isozymes delta and epsilon in cultured neonatal rat cardiac myocytes.
Topics: Animals; Carcinogens; Cell Size; Cells, Cultured; Endothelin-1; Enzyme Activation; Guanidines; Heart Ventricles; Hydrogen-Ion Concentration; Ion Transport; Isoenzymes; Phenylephrine; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Tetradecanoylphorbol Acetate | 1999 |
Differential regulation of 46 and 54 kDa jun N-terminal kinases and p38 mitogen-activated protein kinase by human alpha(1A)-adrenoceptors expressed in Rat-1 cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gene Expression; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Maleimides; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phenylephrine; Phosphoinositide-3 Kinase Inhibitors; Prazosin; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin | 1999 |
Differential regulation of human alpha1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Binding Sites; Cells, Cultured; Down-Regulation; Fibroblasts; Humans; Inositol Phosphates; Phenylephrine; Prazosin; Radioligand Assay; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tetradecanoylphorbol Acetate | 1999 |
Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine.
Topics: Adrenergic alpha-Agonists; Animals; Anion Transport Proteins; Biological Transport; Bradykinin; Carrier Proteins; Diglycerides; Enzyme Inhibitors; Indoles; Intracellular Membranes; Ketoglutaric Acids; Kidney Tubules, Proximal; Male; Maleimides; Phenylephrine; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1999 |
Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by alpha- and beta-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Brimonidine Tartrate; Cell Division; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Drug Interactions; ErbB Receptors; Isoquinolines; Liver; Male; Metaproterenol; Mitogen-Activated Protein Kinase Kinases; Phenylephrine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinases; Quinoxalines; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases | 1999 |
Relationship between intracellular Ca2+ store and protein kinase C in agonist-induced contraction of hypertensive rat aortae.
Topics: Animals; Aorta; Calcium; Carcinogens; Endothelin-1; Enzyme Inhibitors; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma; Serotonin; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
Neuropeptide Y (NPY) potentiates phenylephrine-induced mitogen-activated protein kinase activation in primary cardiomyocytes via NPY Y5 receptors.
Topics: Angiotensin II; Animals; Cells, Cultured; Enzyme Activation; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Neuropeptide Y; Pertussis Toxin; Phenylephrine; Phosphorylation; Protein Kinase C; Receptors, Neuropeptide Y; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Virulence Factors, Bordetella | 2000 |
alpha(1A) adrenergic receptor induces eukaryotic initiation factor 4E-binding protein 1 phosphorylation via a Ca(2+)-dependent pathway independent of phosphatidylinositol 3-kinase/Akt.
Topics: Adaptor Proteins, Signal Transducing; Adrenergic alpha-Agonists; Animals; Calcium; Calmodulin; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Chelating Agents; Enzyme Inhibitors; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Ionophores; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Adrenergic, alpha-1; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Nitric oxide mediated endothelium-dependent relaxation induced by glibenclamide in rat isolated aorta.
Topics: Animals; Aorta; Arginine; Calcimycin; Calcium Chloride; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Role for early growth response-1 protein in alpha(1)-adrenergic stimulation of fibroblast growth factor-2 promoter activity in cardiac myocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Fibroblast Growth Factor 2; Gene Expression Regulation; Heart; Humans; Immediate-Early Proteins; Mice; Myocardium; Nuclear Proteins; Phenylephrine; Promoter Regions, Genetic; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2000 |
Expression and activity of protein kinase D/protein kinase C mu in myocardium: evidence for alpha1-adrenergic receptor- and protein kinase C-mediated regulation.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Cells, Cultured; Enzyme Activation; Female; Heart; Heart Ventricles; Male; Myocardium; Norepinephrine; Phenylephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 2000 |
Changes in protein kinase C isoforms in association with vascular hyporeactivity in cirrhotic rat aortas.
Topics: Animals; Aorta; Biological Transport; Down-Regulation; Intracellular Membranes; Isoenzymes; Liver Cirrhosis, Experimental; Male; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reference Values; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution; Vasoconstriction; Vasoconstrictor Agents; Vasomotor System | 2000 |
Role of protein kinase C in alpha(1)-adrenergic regulation of a(Na)(i) in guinea pig ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Animals; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart Ventricles; Indoles; Intracellular Membranes; Maleimides; Myocardium; Phenylephrine; Potassium; Protein Kinase C; Receptors, Adrenergic, alpha; Sodium; Staurosporine; Strophanthidin; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2000 |
Role for PKC in the adenosine-induced decrease in shortening velocity of rat ventricular myocytes.
Topics: Adenosine; Alkaloids; Animals; Benzophenanthridines; Carcinogens; Cells, Cultured; Cytosol; Enzyme Inhibitors; Heart Ventricles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Phenanthridines; Phenylephrine; Phenylisopropyladenosine; Protein Kinase C; Protein Kinase C-epsilon; Rats; Sarcomeres; Sarcoplasmic Reticulum; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Increased dilator response to heptanol and octanol in aorta from DOCA-salt-hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Dose-Response Relationship, Drug; Heptanol; Hypertension; In Vitro Techniques; Male; Nifedipine; Octanols; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Involvement of adenosine in vascular contractile preconditioning.
Topics: Adenine Nucleotides; Adenosine; Adrenergic alpha-1 Receptor Agonists; Animals; Aorta; Endothelium, Vascular; Glyburide; In Vitro Techniques; Isometric Contraction; Male; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Rats; Stress, Mechanical; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents | 2001 |
AlphaB crystallin translocation and phosphorylation: signal transduction pathways and preconditioning in the isolated rat heart.
Topics: Adrenergic alpha-Agonists; Animals; Anisomycin; Chromatography, Gel; Crystallins; Heart; Immunoblotting; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Mitogen-Activated Protein Kinases; Myocardium; Particle Size; Perfusion; Phenylephrine; Phosphorylation; Protein Synthesis Inhibitors; Protein Transport; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Nuclear factor-kappaB as a target of cyclosporin in acute hypovolemic hemorrhagic shock.
Topics: Animals; Aorta; Blotting, Western; Cells, Cultured; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; In Vitro Techniques; Liver; Macrophage Activation; Macrophages, Peritoneal; Male; Models, Animal; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylephrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shock; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2001 |
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.
Topics: Actin Cytoskeleton; Alkaloids; Animals; Benzophenanthridines; Binding Sites; Detergents; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Heart; Mice; Mice, Transgenic; Mutation; Myocardial Contraction; Papillary Muscles; Phenanthridines; Phenylephrine; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Troponin I | 2002 |
Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein.
Topics: Animals; Endothelin-1; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myocardium; Osmotic Pressure; Phenylephrine; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Alpha(1)-AR-induced positive inotropic response in heart is dependent on myosin light chain phosphorylation.
Topics: Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cardiotonic Agents; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; MAP Kinase Signaling System; Myocardial Contraction; Myosin Light Chains; Papillary Muscles; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; rho-Associated Kinases; Tetradecanoylphorbol Acetate | 2002 |
Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Binding Sites; Cell Line; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Insulin; Isoenzymes; Mitogens; Molecular Sequence Data; Phenylephrine; Phosphorylation; Protein Kinase C; Recombinant Proteins; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Eye Proteins; Lacrimal Apparatus; Male; Peroxidase; Phenylephrine; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Quinazolines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrphostins | 2003 |
NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Apoptosis; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclosporine; DNA-Binding Proteins; Gene Expression; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Ionomycin; Jurkat Cells; Luminescent Proteins; Molecular Sequence Data; Myocytes, Cardiac; NFATC Transcription Factors; Nuclear Proteins; Oligopeptides; Phenylephrine; Protein Isoforms; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2003 |
Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.
Topics: Adenoviridae; Animals; Animals, Newborn; Blotting, Western; Cardiotonic Agents; Endothelin-1; Enzyme Activation; Heart Ventricles; Mutation; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Precipitin Tests; Proline; Protein Kinase C; Protein Kinase C-epsilon; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase Czeta regulates phospholipase D activity in rat-1 fibroblasts expressing the alpha1A adrenergic receptor.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cell Line; Enzyme Inhibitors; Fibroblasts; Gene Expression; Phenylephrine; Phospholipase D; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 2004 |
Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Alkaloids; Animals; Benzophenanthridines; Enzyme Activators; In Vitro Techniques; Isoenzymes; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Penis; Phenanthridines; Phenylephrine; Protein Kinase C; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2004 |
Delayed preconditioning of the human myocardium: signal transduction and clinical implications.
Topics: Acetylcholine; Aged; Alkaloids; Anisomycin; Antihypertensive Agents; Benzophenanthridines; Culture Techniques; Decanoic Acids; Diazoxide; Enzyme Activation; Enzyme Inhibitors; Female; Heart Atria; Humans; Hydroxy Acids; Imidazoles; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Estrone; Gene Expression Regulation; In Vitro Techniques; Kidney Tubules, Proximal; Organic Anion Transporters, Sodium-Independent; Phenylephrine; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 2004 |
alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carcinogens; Cell Line; Extracellular Signal-Regulated MAP Kinases; Glucose; Hypoglycemic Agents; Imidazoles; Insulin; Isoproterenol; Muscle Fibers, Skeletal; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphatidylinositol 3-Kinases; Prazosin; Propranolol; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2005 |
Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes.
Topics: Animals; Binding Sites; Calcineurin; Calcium; Cardiomegaly; Cells, Cultured; Cricetinae; Dogs; Female; Heart; Humans; Ion Transport; Male; Mutation; Myocytes, Cardiac; Phenylephrine; Protein Binding; Rats; Sodium; Sodium-Calcium Exchanger; Tacrolimus; Tetradecanoylphorbol Acetate | 2005 |
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.
Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2006 |
The MLCK-mediated alpha1-adrenergic inotropic effect in atrial myocardium is negatively modulated by PKCepsilon signaling.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiotonic Agents; Heart; Heart Atria; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Mice; Myocardial Contraction; Myosin-Light-Chain Kinase; Phenylephrine; Phosphorylation; Protein Kinase C-epsilon; Receptors, Adrenergic, alpha-1; Sarcoplasmic Reticulum; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2006 |
Roles of protein kinase C, Ca2+, Pyk2, and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK.
Topics: Adrenergic alpha-Agonists; Animals; Blotting, Western; Calcium; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 2; Genes, src; Ionomycin; Lacrimal Apparatus; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phenylephrine; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Alpha1-adrenergic receptor stimulation induces the expression of receptor activator of nuclear factor kappaB ligand gene via protein kinase C and extracellular signal-regulated kinase pathways in MC3T3-E1 osteoblast-like cells.
Topics: 3T3 Cells; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Indoles; Maleimides; Mice; Osteoblasts; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Receptor Activator of Nuclear Factor-kappa B; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Yohimbine | 2007 |
Stimulatory action of protein kinase C(epsilon) isoform on the slow component of delayed rectifier K+ current in guinea-pig atrial myocytes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Heart Atria; In Vitro Techniques; Indoles; Isoenzymes; Maleimides; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Peptide Fragments; Phenylephrine; Prazosin; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Vascular myorelaxing activity of isolates from South African Hyacinthaceae partly mediated by activation of soluble guanylyl cyclase in rat aortic ring preparations.
Topics: Animals; Aorta; Bufanolides; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Ion Channel Gating; Isoflavones; Liliaceae; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Plant Extracts; Potassium Channels; Potassium Compounds; Rats; Rats, Sprague-Dawley; Sesquiterpenes; South Africa; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Post-transcriptional control of human ether-a-go-go-related gene potassium channel protein by alpha-adrenergic receptor stimulation.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Blotting, Western; Cell Line; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Phenylephrine; Phosphorylation; Protein Kinase C; Rats; RNA Processing, Post-Transcriptional; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
Activation of extracellular-signal regulated kinase by platelet-derived growth factor is potentiated by phenylephrine in primary cultures of adult rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Brimonidine Tartrate; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Male; Metaproterenol; Phenylephrine; Phosphorylation; Platelet-Derived Growth Factor; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2011 |
Signal transduction mechanism for potentiation by α1- and β2-adrenoceptor agonists of L-ascorbic acid-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Animals; Ascorbic Acid; Cell Proliferation; Cells, Cultured; DNA; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Male; Metaproterenol; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Receptor, IGF Type 1; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-2; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2013 |