tetradecanoylphorbol acetate has been researched along with paclitaxel in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.65) | 18.7374 |
| 1990's | 20 (46.51) | 18.2507 |
| 2000's | 18 (41.86) | 29.6817 |
| 2010's | 3 (6.98) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Li, F; Wang, L; Wang, MK; Yu, K; Zhang, XL | 1 |
| Ide, T; Tsuji, K; Ueno, A | 1 |
| Bershadskiĭ, AD; Gel'fand, IM; Ivanova, OIu; Liass, LA; Pletiushkina, OIu; Vasil'ev, IuM | 1 |
| Bershadsky, AD; Gelfand, IM; Ivanova, OY; Lyass, LA; Pletyushkina, OY; Vasiliev, JM | 1 |
| Danowski, BA | 1 |
| Antin, P; Dlugosz, A; Dubyak, G; Forry-Schaudies, S; Holtzer, H | 1 |
| Fujiwara, Y; Inomata, M; Kaneko, A; Kawashima, K; Kunikane, H; Saijo, N; Tanaka, Y | 1 |
| Hume, DA; Sweet, MJ | 1 |
| Jack, RM; Lowenstein, BA; Nicholson-Weller, A | 1 |
| Hasegawa, T | 1 |
| Blagosklonny, MV; Neckers, LM; Nguyen, P; Schulte, T; Trepel, J | 1 |
| Aderem, A; Rosen, A; Veis, N | 1 |
| Liu, D; Mori, H; Sy, MS; Zhang, D | 1 |
| Bement, WM; Canman, JC | 1 |
| Huang, TS; Jee, SH; Kuo, ML; Shen, SC | 1 |
| Chung, HT; Jun, CD; Kook, YA; Kwak, HJ; Lee, SJ; Pae, HO; Park, RK; Yoo, JC | 1 |
| Choi, BM; Chung, HT; Chung, HY; Jun, CD; Kwak, HJ; Na, YG; Pae, HO; Park, RK; Park, WY; Park, YC; Seo, JS; Yoo, JC | 1 |
| Czuba, ZP; Hasiński, P; Król, W; Nowowiejska, A | 1 |
| Craig, RW; Eastman, A; Townsend, KJ; Traupman, MA; Trusty, JL | 1 |
| Crépieux, P; Hiscott, J; Kwon, H; Leclerc, N; Lin, R; Spencer, W | 1 |
| Matsuura, M; Nakano, M; Saito, S; Tominaga, K | 1 |
| Bergan, RC; Blagosklonny, MV; Chuman, Y; Fojo, T | 1 |
| Chou, CY; Hsu, KF; Hsu, KS; Shen, MR; Wu, ML | 1 |
| Heckman, CA; Mukherjee, R; Plummer, HK | 1 |
| Choi, BM; Chung, HT; Lee, EJ; Pae, HO; Song, YS; Yoo, JC | 1 |
| Chang, YG; Fujikawa-Yamamoto, K; Ishikawa, Y; Li, AL; Murakami, M; Yamaguchi, N; Zong, ZP | 1 |
| Craig, RW; Domina, AM; Smith, JH | 1 |
| Bates, SE; Bishop, PC; Blagosklonny, MV; Fojo, T; Robey, R | 1 |
| Ballestrem, C; Hinz, B; Imhof, BA; Wehrle-Haller, B | 1 |
| Kucik, DF; Li, J; Zhou, X | 1 |
| Aboud, M; Ben-Aroya, Z; Butovsky, E; Flügel, RM; Grunspan, A; Hallak, M; Kedar, I; Livneh, E; Löchelt, M; Torgeman, A; Wolfson, M; Zelin, E | 1 |
| Alemany, S; Caivano, M; Cohen, P; Rodriguez, C | 1 |
| Fujikawa-Yamamoto, K; Han, JF; Katsuda, S; Matsui, S; Zong, ZP | 1 |
| Craig, RW; Domina, AM; Gregory, MA; Hann, SR; Vrana, JA | 1 |
| Ahmed, W; Dent, P; Grant, S; Rahmani, M | 1 |
| Dangi, S; Shapiro, P | 1 |
| Avila, GE; Chang, RL; Conney, AH; Crowell, P; Cui, XX; Hansson, A; Lin, Y; Lou, YR; Lu, YP; Rabson, AB; Ryan, AD; Shih, WJ; Suh, J; Zheng, X | 1 |
| Alappat, EC; Boyerinas, B; Feig, C; Kidd, VJ; Murmann, AE; Osborn, SL; Peter, ME; Samuels, M; Slaughter, CA; Tang, WJ; Thorburn, A; Volkland, J; Winoto, A | 1 |
| Avila, GE; Chang, RL; Conney, AH; Cui, XX; Garzotto, M; Hebbar, V; Kong, AN; Lin, Y; Lu, SE; Rabson, AB; Shih, WJ; Zheng, X | 1 |
| Choi, YH; Kim, GY; Kim, WJ; Moon, DO; Moon, SK | 1 |
1 review(s) available for tetradecanoylphorbol acetate and paclitaxel
| Article | Year |
|---|---|
Interactions between IFs, microtubules, and myofibrils in fibrogenic and myogenic cells.
Topics: Actin Cytoskeleton; Alkaloids; Animals; Cytoskeleton; Demecolcine; Desmin; Ethyl Methanesulfonate; Humans; Intermediate Filaments; Microtubules; Muscles; Myofibrils; Paclitaxel; Tetradecanoylphorbol Acetate; Vimentin | 1985 |
42 other study(ies) available for tetradecanoylphorbol acetate and paclitaxel
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Cytotoxic phorbol esters of Croton tiglium.
Topics: Antineoplastic Agents; Croton; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Humans; Inhibitory Concentration 50; Liver Neoplasms; Molecular Structure; Phorbol Esters; Seeds | 2013 |
Inhibitory effect of taxol, a microtubule stabilizing agent, on induction of DNA synthesis is dependent upon cell lines and growth factors.
Topics: Alkaloids; Animals; Blood; Cell Line; Culture Media; DNA; Epidermal Growth Factor; Fibroblasts; Humans; Microtubules; Paclitaxel; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
[The role of intermediate filaments in forming cellular processes induced in fibroblasts by the tumor promoter TPA].
Topics: Actins; Alkaloids; Animals; Cell Line, Transformed; Cells, Cultured; Demecolcine; Drug Interactions; Fibroblasts; Fluorescent Antibody Technique; Intermediate Filaments; Mice; Microtubules; Paclitaxel; Tetradecanoylphorbol Acetate | 1992 |
Cytoskeletal reorganizations responsible for the phorbol ester-induced formation of cytoplasmic processes: possible involvement of intermediate filaments.
Topics: Alkaloids; Animals; Cell Line; Clone Cells; Cytoplasm; Cytoskeleton; Demecolcine; Intermediate Filaments; Mice; Paclitaxel; Tetradecanoylphorbol Acetate | 1990 |
Fibroblast contractility and actin organization are stimulated by microtubule inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Colforsin; Demecolcine; Fibroblasts; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Photomicrography; Tetradecanoylphorbol Acetate; Vinblastine | 1989 |
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
Topics: Apoptosis; Calcimycin; Cell Cycle; Cell Survival; Child, Preschool; Cholera Toxin; Colforsin; DNA, Neoplasm; Enzyme Inhibitors; Ethers, Cyclic; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Male; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Retinoblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
RAW264 macrophages stably transfected with an HIV-1 LTR reporter gene provide a sensitive bioassay for analysis of signalling pathways in macrophages stimulated with lipopolysaccharide, TNF-alpha or taxol.
Topics: Animals; Cell Line; Gene Expression; Genes, Reporter; HIV Long Terminal Repeat; HIV-1; Humans; Lipopolysaccharides; Luciferases; Macrophages; Mice; Paclitaxel; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1995 |
Regulation of C1q receptor expression on human polymorphonuclear leukocytes.
Topics: Carrier Proteins; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paclitaxel; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
Production of a unique antibody specific for membrane ruffles and its use to characterize the behavior of two distinct types of ruffles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Antigens, Surface; Calmodulin; Cell Membrane; Chick Embryo; Culture Media, Serum-Free; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Isoquinolines; Kinetics; Membrane Proteins; Molecular Weight; Nocodazole; Paclitaxel; Piperazines; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line; Enzyme Activation; Female; HL-60 Cells; Humans; Male; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Microtubule-active agents mimic lipopolysaccharides in priming macrophages for enhanced arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Colchicine; Female; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Microtubules; Nocodazole; Paclitaxel; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Binding of CD44 to hyaluronic acid can be induced by multiple signals and requires the CD44 cytoplasmic domain.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; CD3 Complex; Colchicine; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin D; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Humans; Hyaluronan Receptors; Hyaluronic Acid; Ionomycin; Ionophores; Jurkat Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Paclitaxel; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Microtubules suppress actomyosin-based cortical flow in Xenopus oocytes.
Topics: Actins; Actomyosin; Animals; Cell Division; Female; Intermediate Filaments; Keratins; Microscopy, Fluorescence; Microtubules; Models, Biological; Nocodazole; Oocytes; Paclitaxel; Tetradecanoylphorbol Acetate; Tubulin; Xenopus laevis | 1997 |
Taxol-induced p34cdc2 kinase activation and apoptosis inhibited by 12-O-tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; CDC2 Protein Kinase; Enzyme Activation; Humans; Paclitaxel; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Enhancing and priming of macrophages for superoxide anion production by taxol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bucladesine; Cell Line; Colchicine; Macrophage Activation; Mice; Paclitaxel; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
The role of inducible 70-kDa heat shock protein in cell cycle control, differentiation, and apoptotic cell death of the human myeloid leukemic HL-60 cells.
Topics: Apoptosis; Base Sequence; Cell Cycle; Cell Differentiation; DNA Damage; DNA Fragmentation; DNA, Recombinant; Gene Expression; Granulocytes; Hematopoiesis; HL-60 Cells; HSP70 Heat-Shock Proteins; Humans; Macrophages; Nitric Oxide; Nitroprusside; Paclitaxel; Tetradecanoylphorbol Acetate | 1998 |
The effects of taxol (paclitaxel) on chemiluminescence of neutrophils, macrophages and J.774.2 cell line.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Free Radicals; Luminescent Measurements; Macrophages; Macrophages, Peritoneal; Mice; Neutrophils; Paclitaxel; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1998 |
Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Death; Cisplatin; Colchicine; Humans; Leukemia, Myeloid, Acute; Microtubules; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Paclitaxel; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine | 1998 |
Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation.
Topics: 3T3 Cells; Animals; Base Sequence; Biopolymers; Cell Line; COS Cells; DNA Primers; DNA-Binding Proteins; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Humans; Hydrolysis; I-kappa B Proteins; Mice; Microtubules; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1999 |
Lipopolysaccharide tolerance in murine peritoneal macrophages induces downregulation of the lipopolysaccharide signal transduction pathway through mitogen-activated protein kinase and nuclear factor-kappaB cascades, but not lipopolysaccharide-incorporatio
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Drug Tolerance; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase 1; NF-kappa B; Paclitaxel; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 1999 |
Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Genes, ras; Humans; Leukemia, Myeloid; MAP Kinase Kinase Kinase 1; Microtubules; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Modulation of volume-sensitive Cl - channels and cell volume by actin filaments and microtubules in human cervical cancer HT-3 cells.
Topics: Actins; Cell Size; Chloride Channels; Colchicine; Cytochalasin B; Female; Humans; Hypotonic Solutions; Membrane Potentials; Microtubules; Osmotic Pressure; Paclitaxel; Patch-Clamp Techniques; Phalloidine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1999 |
Enhancement of the transformed shape phenotype by microtubule inhibitors and reversal by an inhibitor combination.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Colchicine; Insulin; Microtubules; Monensin; Paclitaxel; Phenotype; Rats; Tetradecanoylphorbol Acetate; Valinomycin | 2000 |
12-O-tetradecanoyl phorbol 13-acetate, protein kinase C (PKC) activator, protects human leukemia HL-60 cells from taxol-induced apoptosis: possible role for extracellular signal-regulated kinase.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; DNA Fragmentation; Down-Regulation; Enzyme Activators; Extracellular Space; HL-60 Cells; Humans; MAP Kinase Signaling System; Nucleosomes; Paclitaxel; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 2000 |
Involvement of protein kinase C in taxol-induced polyploidization in a cultured sarcoma cell line.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cell Cycle; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Fluorescent Antibody Technique; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Paclitaxel; Polyploidy; Protein Kinase C; Sarcoma, Experimental; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured | 2000 |
Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition.
Topics: Burkitt Lymphoma; Cell Cycle; Cell Survival; Enzyme Activation; Enzyme Inhibitors; G2 Phase; Humans; Marine Toxins; Microtubules; Mitogen-Activated Protein Kinases; Mitosis; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nocodazole; Okadaic Acid; Oxazoles; Paclitaxel; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine | 2000 |
Loss of cell cycle control allows selective microtubule-active drug-induced Bcl-2 phosphorylation and cytotoxicity in autonomous cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; Female; HL-60 Cells; Humans; Microtubules; Mitosis; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Quinazolines; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured; Tyrphostins | 2000 |
Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control-directed cell migration.
Topics: Actins; Animals; Cell Line; Cell Movement; Cytoplasm; Green Fluorescent Proteins; Luminescent Proteins; Melanocytes; Melanoma, Experimental; Mice; Microtubules; Nocodazole; Paclitaxel; Proto-Oncogene Proteins c-kit; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2000 |
The microtubule cytoskeleton participates in control of beta2 integrin avidity.
Topics: Animals; Antineoplastic Agents; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Line; Cell Line, Transformed; Colchicine; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Gout Suppressants; Humans; Integrins; Macrophages; Mice; Microscopy, Video; Microtubules; Models, Statistical; Nocodazole; Paclitaxel; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 2001 |
Activation of HTLV-I long terminal repeat by stress-inducing agents and protection of HTLV-I-infected T-cells from apoptosis by the viral tax protein.
Topics: Antineoplastic Agents; Apoptosis; Carcinogens; Cell Line; Cisplatin; Etoposide; Gene Expression Regulation; Gene Products, tax; Genes, Reporter; Human T-lymphotropic virus 1; Humans; Methylcholanthrene; Paclitaxel; Protein Isoforms; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Terminal Repeat Sequences; Tetracycline; Tetradecanoylphorbol Acetate; Transfection | 2001 |
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fibrinolytic Agents; Gene Expression Regulation, Enzymologic; Indoles; Ligands; Lipopolysaccharides; Macrophages; Maleimides; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Precipitin Tests; Prostaglandin D2; Protein Isoforms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones; Time Factors | 2003 |
Phorbol myristate induces apoptosis of taxol-resistant sarcoma cells in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; DNA; Drug Resistance, Neoplasm; Drug Synergism; Flow Cytometry; G1 Phase; Genes, bcl-2; Genes, p53; Male; Mice; Mice, Inbred BALB C; Mitosis; Oncogene Protein p21(ras); Paclitaxel; Polyploidy; Resting Phase, Cell Cycle; S Phase; Sarcoma, Experimental; Survival; Tetradecanoylphorbol Acetate | 2004 |
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Carcinogens; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Okadaic Acid; Paclitaxel; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection | 2004 |
The cyclin-dependent kinase inhibitor p21(CIP1/WAF1) blocks paclitaxel-induced G2M arrest and attenuates mitochondrial injury and apoptosis in p53-null human leukemia cells.
Topics: Antisense Elements (Genetics); Apoptosis; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Doxycycline; Flow Cytometry; G2 Phase; Humans; Jurkat Cells; Leukemia; Membrane Potentials; Mitochondria; Mitotic Index; Paclitaxel; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; U937 Cells | 2004 |
Cdc2-mediated inhibition of epidermal growth factor activation of the extracellular signal-regulated kinase pathway during mitosis.
Topics: CDC2 Protein Kinase; Cell Line, Tumor; Densitometry; Enzyme Activation; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Mitosis; Models, Biological; Nocodazole; Paclitaxel; Phosphorylation; Protein Binding; Protein Biosynthesis; Proto-Oncogene Proteins c-raf; Purines; Roscovitine; Signal Transduction; SOS1 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Vinblastine | 2005 |
Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice.
Topics: Animals; Apoptosis; Body Weight; Cell Cycle; Cell Proliferation; Humans; Immunohistochemistry; Male; Mice; Neoplasm Transplantation; Paclitaxel; Pancreatic Neoplasms; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Retinoblastoma Protein; Sulindac; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Tretinoin; Tumor Cells, Cultured | 2005 |
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Casein Kinase Ialpha; Cell Cycle; Cell Line; Cell Nucleus; Concanavalin A; Cytosol; Enzyme Inhibitors; Fas-Associated Death Domain Protein; HeLa Cells; Humans; Isoquinolines; Jurkat Cells; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitosis; Molecular Sequence Data; Mutation; Paclitaxel; Phosphorylation; Protein Binding; Protein Transport; RNA, Small Interfering; Sequence Homology, Amino Acid; Serine; Spindle Apparatus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Injections, Intraperitoneal; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Nude; Mice, SCID; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Treatment Outcome; Xenograft Model Antitumor Assays | 2006 |
Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.
Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Flow Cytometry; Gossypol; Humans; Intercellular Adhesion Molecule-1; NF-kappa B; Okadaic Acid; Paclitaxel; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2011 |