Page last updated: 2024-08-23

tetradecanoylphorbol acetate and okadaic acid

tetradecanoylphorbol acetate has been researched along with okadaic acid in 355 studies

Research

Studies (355)

TimeframeStudies, this research(%)All Research%
pre-19907 (1.97)18.7374
1990's271 (76.34)18.2507
2000's71 (20.00)29.6817
2010's6 (1.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alfonso, A; Botana, LM; Botana, MA; Cabado, AG; Louzao, MC; Vieytes, MR1
Schäfer, C; Wagner, AC; Williams, JA1
Emoto, S; Ichikawa, A; Imanishi, N; Kawai, H; Ohgoh, M; Ohmori, E; Yatsunami, K1
Fujiki, H; Fujiwara, Y; Kasahara, K; Nishio, K; Nishiwaki, S; Ohata, M; Saijo, N; Sugimoto, Y1
Schönthal, A1
Beguinot, F; Condorelli, G; Formisano, P; Miele, C1
Danø, K; Lund, LR1
Badwey, JA; Ding, J2
Carter, BZ; Malter, JS; Pekala, PH; Stephens, JM1
Medcalf, RL1
Berthoud, VM; Hertzberg, EL; Ledbetter, ML; Sáez, JC1
Kiss, Z2
Hattori, M; Horiuchi, R1
Iguchi, A; Ishiguro, T; Miura, H; Nonogaki, K; Sakamoto, N; Tamagawa, T; Uemura, K1
Keller, H; Kreienbühl, P; Niggli, V1
Bu, X; Hagedorn, CH1
Deguchi, K; Ito, M; Kobayashi, K; Kuno, T; Morita, K; Nagao, M; Nakano, T; Nishikawa, M; Shima, H; Tanaka, C1
Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S1
Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S1
Chubb, CH; Fujiki, H; Giometti, C; Huberman, E; Kiguchi, K1
Blackburn, R; Golding, H; Hillman, K; Manischewitz, J; Norcross, M; Qian, J; Roderiquez, G; Siegel, JN1
Enomoto, T; Sawada, S; Tauchi, H1
Cao, X; Chua, SP; Guy, GR; Tan, YH1
Ashino-Fuse, H; Oikawa, T; Shimamura, M; Suganuma, M1
Goad, DL; Meurer, EA; Petrou, CP; Tashjian, AH; Voelkel, EF1
Chambers, TC; Kuo, JF; Zheng, B1
Chao, R; Hannun, YA; Khan, W1
Gschwendt, M; Kittstein, W; Lindner, D; Marks, F1
Candeo, P; Favaron, M; Lengyel, I; Manev, H; Manev, RM; Rimland, JM1
Datta, R; Hass, R; Kharbanda, S; Kufe, D; Nakamura, T; Rubin, E1
Deli, E; Kiss, Z1
Chen, ZH; Gopalakrishna, R; Gundimeda, U1
Kuo, JF; Woo, CF; Zheng, B1
Levine, L1
Buckley, S; Cosico, L; Seth, R; Tayag, A; Warburton, D1
Livne, AA; Pouyssegur, J; Sardet, C1
Aharonovitz, O; Fridman, H; Livne, AA; Markus, S; Tsukitani, Y1
Carpenter, G; Hernández-Sotomayor, SM; Mumby, M1
Olashaw, NE; Pledger, WJ; Winston, JT1
Alberts, AS; Feramisco, JR; Frost, JA; Schönthal, A1
Brooks, JW; Chedid, M; Mizel, SB; Yoza, BK1
Alexandre, H; Mulnard, J; Tsukitani, Y; Van Cauwenberge, A1
Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP1
Druker, B; Griffin, JD; Kanakura, Y; Mamon, HJ; Okuda, K; Roberts, TM; Wood, KW1
Nagamine, Y; Ziegler, A1
Rieber, M; Rieber, MS1
Bushfield, M; Houslay, MD; Lavan, BE1
Cervello, M; Landreth, G; Lemmon, V; Rutishauser, U1
Haystead, TA; Krebs, EG; Licciardi, KA; Meier, KE1
Barratt, MJ; Mahadevan, LC; Willis, AC1
Fujiwara, C; Mochizuki, N; Oda, T; Ohta, M; Sagara, J; Shimizu, N; Utiyama, H1
Buxbaum, JD; Cicchetti, P; Czernik, AJ; Ehrlich, ME; Fracasso, RP; Gandy, SE; Greengard, P; Ramabhadran, TV; Unterbeck, AJ1
Churcher, Y; Gomperts, BD; Kramer, KM1
Fauci, AS; Fujiki, H; Kehrl, JH; Kim, SJ; Norcross, MA; Rieckmann, P; Sporn, MB; Thévenin, C1
Bungo, M; Fujiki, H; Fujiwara, Y; Kasahara, K; Nakagawa, K; Niimi, S; Nishio, K; Saijo, N; Sugimoto, Y1
Rhoads, RE; Rush, JS; Rychlik, W; Waechter, CJ1
Mikalsen, SO; Rivedal, E; Sanner, T1
Fujiki, H; Hiro, M; Imanishi, Y; Kimura, S; Nam, KY1
Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Tamura, T; Tsurufuji, S; Watanabe, M1
Gschwendt, M; Kittstein, W; Marks, F; Mieskes, G1
Fujiki, H; Hirota, M; Suganuma, M; Sugimura, T; Suguri, H; Takagi, K; Yoshizawa, S1
Fujiki, H; Ikeda, I; Kitani, H; Nagao, M; Rapp, U; Sakai, R; Sugimura, T; Takaku, F1
Brankow, DW; Fujiki, H; Herschman, HR; Lim, RW1
Fujiki, H; Hirota, M; Nakayasu, M; Ojika, M; Suganuma, M; Sugimura, T; Suguri, H; Wakamatsu, K; Yamada, K; Yoshizawa, S1
Fujiki, H; Issinger, OG; Martin, T; Olson, M; Richter, WW1
Huang, TS; Kuo, ML; Lin, JK1
Fujiwara, Y; Inomata, M; Kaneko, A; Kawashima, K; Kunikane, H; Saijo, N; Tanaka, Y1
Karimi, K; Lennartz, MR1
Buyon, JP; Merrill, JT; Winchester, RJ1
Malbon, CC; Strassheim, D1
Fetz, I; Fölsch, UR; Höcker, M; Meyer-Alber, A; Schmidt, WE; Waschulewski, IH1
Cherington, V; Riseberg, JC; Tischler, AS1
Botana, LM; Estévez, MD; Vieytes, MR2
García-Sáinz, JA; González-Espinosa, C1
Bruder, JT; Geppert, TD; Owaki, H; Rapp, UR; Whitehurst, CE1
Jones, PM; Persaud, SJ; Wheeler-Jones, CP1
Chik, CL; Ho, AK; Karpinski, E; Kovacs, CS; Li, B1
Arkhammar, P; Berggren, PO; Bertorello, AM; Efendić, S; Zaitsev, SV1
Hatake, K; Sakamoto, K; Wakabayashi, I1
Greene, MI; Samanta, A1
Dickinson, CJ; Seva, C; Takeuchi, Y; Todisco, A; Yamada, T1
Bishop, PR; Coffey, RJ; DuBois, RN; Graves-Deal, R1
Marantz, Y; Naor, Z; Przedecki, F; Reiss, N1
Coezy, E; de Neef, RS; Fathallah, H; Giraud, F; Hardy-Dessources, MD1
Chong, AS; Curry, MS; Edwards, BS; Graf, LH; Southon, EA1
Marksitzer, R; Menoud, PA; Nagamine, Y; Stief, A1
Beguinot, L; Johnson, AC; Pastan, I; Yamazaki, H1
Indelicato, SR; Kirk, G; Kitamura, T; Meyer, L; Miyajima, A; Muir, VC; Parce, JW; Wada, HG1
Azzi, A; Boscoboinik, D; Galeotti, T1
Augenlicht, LH; Velcich, A1
Bertrand, R; Jenkins, J; Pommier, Y; Solary, E1
Bona, BJ; Borror, KC; DeFranco, DB; Moyer, ML; Nordeen, SK1
Heider, H; Widmer, HR1
Edashige, K; Inoue, M; Sato, EF; Utsumi, K1
Combadière, C; Djerdjouri, B; Hakim, J; Pedruzzi, E; Périanin, A1
Ilvonen, E; Kähäri, VM; Uitto, J; Westermarck, J1
Beltrán, LM; DiGiovanni, J; Kiguchi, K; Rho, O; You, J1
Wei, L; Yung, BY1
Aggarwal, BB; Singh, S1
Kim, NH; Menino, AR1
Chang, PL; Prince, CW; Yang, WC1
Baeuerle, PA; Henkel, T; Pahl, HL; Schmidt, KN; Traenckner, EB; Wilk, S1
Chubb, CH; Fujiki, H; Glesne, D; Huberman, E; Kiguchi, K1
Bissonnette, M; Brasitus, TA; Jiang, K; Khare, S; Niedziela, SM; Roy, HK; Sitrin, MD; Wali, RK1
Ikeda, SR; Zhu, Y1
Kähäri, VM; Keski-Oja, J; Lohi, J; Westermarck, J1
Pshenichkin, SP; Wise, BC1
Giese, G; Kubbies, M; Scherbarth, A; Traub, P; Wiegers, W1
Volz, A1
Gopalakrishna, R; Hinton, DR; Kohen, L; Oganesian, A; Ryan, SJ; Sakamoto, H; Sakamoto, T1
Ikonen, T; Jänne, OA; Kallio, PJ; Palvimo, JJ; Reinikainen, P1
Falk, W; Krammer, PH; Praast, G; Stoeck, M; Stricker, K; Tsukitani, Y1
Ito, Y; Kotoyori, J; Kozawa, O; Oiso, Y; Suzuki, A; Watanabe, Y1
Sen, AK; Torchia, J; Yi, Q1
Collins, CA; Ferro, KL; Lin, SX1
Joggerst, B; Parton, RG; Simons, K1
Granner, DK; Noisin, EL; O'Brien, RM1
de Ondarza, J; Hootman, SR; Wilkins, TJ1
Beltrán, LM; DiGiovanni, J; Rupp, T; Wang, XJ; Warren, BS1
Blenis, J; Emoto, Y; Hirano, M; Kharbanda, S; Kufe, D; Saleem, A; Sukhatme, V1
Forchhammer, J; Jensen, PO; Larsen, JK; Lund, LR; Skouv, J1
Dumont, FJ; Kastner, CA1
Leslie, CC; Qiu, ZH1
Hadjiconstantinou, M; Neff, NH; Young, EA1
Fujii, J; Ikeda, Y; Miyoshi, E; Nakata, T; Taniguchi, N1
Bischof, D; Hammond, KD1
Bollen, M; De Smedt, H; Himpens, B1
Alfonso, A; Botana, LM; Botana, MA; Vieytes, MR1
Fernández, MT; Gascón, S; Novelli, A; Torreblanca, A; Zitko, V1
Aussel, C; Bernard, A; Breittmayer, JP; Deckert, M1
Cheong, J; Kaneko, S; Matsushima, K; Murakami, S; Ohno, S1
Baldini, P; Bellucci, V; Incerpi, S; Luly, P; Zannetti, A1
Ammälä, C; Berggren, PO; Bokvist, K; Eliasson, L; Honkanen, RE; Rorsman, P; Sjöholm, A1
Ishibashi, S; Kuwana, M; Okamura, N; Sakai, M; Sasaki, J; Yamaguchi, M1
Fu, SM; Kannapell, CC; Sung, SS; Xia, HZ1
de Carvalho, MS; Leslie, CC; Qiu, ZH1
Deuticke, B; Fischer, Y; Kammermeier, H; Rose, H; Thomas, J1
Husøy, T; Mikalsen, SO; Sanner, T1
Hurme, M; Matikainen, S1
Beck, CA; Edwards, DP; Nordeen, SK; Weigel, NL1
Benistant, C; Gustavsson, L; Hoek, JB; Moehren, G; Rubin, R; Torres-Marquez, ME1
Emoto, Y; Kharbanda, S; Kufe, D; Rapp, U; Saleem, A; Stone, R1
Floer, M; Stock, J1
Colucci, WS; Izzo, NJ; Tulenko, TN1
Mayer, AM; Spitzer, JA1
Ishaque, A; Kazmi, SM; Lau, C; Plante, RK; Visconti, V1
Cormont, M; Le Marchand-Brustel, Y; Tanti, JF; Tavitian, A; Van Obberghen, E; Zahraoui, A1
Daneschmand, H; Klein, H; Probst, I; Quentmeier, A; Unthan-Fechner, K1
Lewis, CE; McGee, JO; Pusztai, L1
Finnegan, SG; Koenig, E; Lemmon, VP1
Aggarwal, BB; Higuchi, M1
Kimura, M; Satoh, S; Shibuya, M; Sugita, K; Suzuki, Y; Takayasu, M1
Holst, E; Houweling, M; Sundler, R; Svensson, U1
Berkow, RL; Dodson, RW1
Armerding, D; Hren, A1
Amaral, MC; Casillas, AM; Nel, AE1
Kharbanda, S; Kufe, DW; Saleem, A; Slapak, CA1
Barclay, CG; Brennand, JE; Calder, AA; Kelly, RW1
Bishop, JM; McMahon, M; Samuels, ML; Weber, MJ1
Fujiki, H; Okabe, S; Suganuma, M; Yatsunami, J; Yoshizawa, S1
Amaral, K; Casillas, AM; Chegini-Farahani, S; Nel, AE1
Asakura, R; Chida, K; Ikuta, T; Kasahara, K; Kuroki, T1
Heimerl, P; Hofer, HW; Stader, C; Willmann, R1
Dussault, JH; Etongue-Mayer, P; Puymirat, J1
Houslay, MD; Zeng, L1
Chen, G; Gao, XM; Newell, SW; Perchellet, EM; Perchellet, JP1
Kasai, M; Kiyosue, K; Sato, SB; Taguchi, T; Toyama, S1
Buckle, RS; Cano, E; Hazzalin, CA; Kardalinou, E; Mahadevan, LC1
Callahan, KS; Terry, CM1
Budunova, IV; Carbajal, S; Slaga, TJ1
Bondurant, MC; Bu, X; Hagedorn, CH1
Goracci, G; Gresele, P; Iorio, P; Nenci, GG; Nucciarelli, F; Stasi, M; Vezza, R1
Azzi, A; Bartoli, GM; Boscoboinik, D; Maroni, P; Tasinato, A1
Handschumacher, RE; Li, W1
el-Deiry, WS; Zeng, YX1
Israël, A; Logeat, F; MacKichan, ML1
Braconi Quintaje, S; Church, DJ; Hemmings, BA; Lang, U; Rebsamen, M; Valloton, MB1
Bagenstose, SE; Newhouse, YG; Whisler, RL1
Chang, HC; Lee, SC; Yang, SD1
Kambayashi, J; Kawasaki, T; Monden, M; Okuyama, M; Sakon, M1
Dahlgren, C; Harbecke, O; Lundqvist, H1
Daniels, M; Hu, RM; Levin, ER; Pedram, A; Prins, BA; Weber, MJ1
Asano, T; Hasegawa, K; Inaguma, Y; Ito, H; Kato, K; Kozawa, O1
Azuma, A; Hashimoto, Y; Hioki, E; Iwasaki, S; Kobayashi, Y; Miyachi, H2
Vernon, RG1
Chandok, MR; Sopory, SK2
Fong, LG1
Liedtke, CM; Thomas, L1
Dowd, LA; Robinson, MB1
Lloret, S; Moreno, JJ; Torrent, M1
Bréant, B; Karlsson, T; Lavergne, C; Mares, J; Welsh, M1
del Castillo-Olivares, A; Esteban del Valle, A; Márquez, J; Medina, MA; Núñez de Castro, I1
Raghow, R; Wang, Q1
Watts, RG1
Aggarwal, BB; Burke, TR; Grunberger, D; Natarajan, K; Singh, S1
Orlicky, DJ1
Abe, H; Obinata, T; Okada, K; Takano-Ohmuro, H1
Rebel, G; Tchoumkeu-Nzouessa, GC1
Hidaka, H; Hisatomi, M; Niki, I1
Marriott, I; Mason, MJ1
Kan, H; Malik, KU; Ruan, Y1
Bajpai, A; Brahmi, Z1
Shaw, MK1
Bornancin, F; Hansra, G; Hemmings, BA; Parker, PJ; Whelan, R1
Gromadzinska, E; Lachowicz, L; Zylinska, L1
Chan, YJ; Chiou, CJ; Hayward, GS; Huang, Q1
Hamm-Alvarez, SF; Kedes, L; Sussman, MA; Vilalta, PM; Welch, S1
Grumbles, RM; Howell, DS; Jeffrey, JJ; Shao, L1
Ho, DT; Murphy, TH; Shayan, H1
Desrivières, S; Ferrari, S; Merćep, L; Volarević, S1
Cabrera Oliva, J; Estévez, F; Fanjul, LF; González Reyes, J; González Robaina, I; Hernández, I; López Blanco, F; Quintana Aguiar, J; Ruiz de Galarreta, CM; Santana, P1
Bell, RL; Carter, GW; Cugier, DJ; Ennis, BW; Glaser, KB; Hulkower, KI; Li, J; Otis, ER1
Ainbinder, E; Bergelson, S; Daniel, V; Pinkus, R1
Grove, DS; Mastro, AM1
Coffey, LL; Reith, ME; Zhang, L1
Farshori, P; Holzbaur, EL1
Bruggeman, CA; Couwenberg, FM; Heemskerk, JW; Hulsbosch, MM; Slobbe-van Drunen, ME; van Dam-Mieras, MC; Vossen, RC1
Fujiki, H; Imanishi, Y; Kimura, S; Kitano, K; Nam, KY1
Casey, ML; Devora, GA; MacDonald, PC; Mibe, M; Morimoto, T1
Kähäri, VM; Seth, A; Westermarck, J1
Clerk, A; Sugden, PH1
Jorcano, JL; Paramio, JM1
Kwan, CY; Leung, YM; Loh, TT1
Azuma, A; Hashimoto, Y; Kato, F; Kato, M; Kobayashi, Y; Miyachi, H; Ogasawara, A; Uchimura, E; Watanabe, N1
Baylink, DJ; Mohan, S; Sampath, K; Srinivasan, N1
Arens, HJ; Hengstler, JG; Oesch, F; Oesch-Bartlomowicz, B; Richter, B1
Badwey, JA; Ding, J; Ellis, BA; Heyworth, PG; Robinson, JM1
Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Node, K; Okuyama, Y; Sato, H; Ueda, Y; Yoshida, K1
Gatti, A; Robinson, PJ1
Orchard, MA; Trotter, PJ; Walker, JH1
Aguayo, LG; Espinoza, F; Tapia, JC1
Agarwal, S; Aggarwal, BB; Chainy, GB; Chaturvedi, MM; Darnay, BG; Kumar, A1
Ito, M; Kawamura, T; Kikuchi, K; Komatsu, M; Mizuno, Y; Nakano, T; Takizawa, N1
Azuma, A; Hashimoto, Y; Miyachi, H; Ogasawara, A1
Kanai, M; Mullen, C; Podolsky, DK1
Blakely, RD; Giovanetti, E; Qian, Y; Ramamoorthy, S1
Gylfe, E; Liu, YJ1
Bhardwaj, D; Eyster, KM; Mijovic, JE; Olson, DM; Zakar, T1
Aggarwal, BB; Chaturvedi, MM; Manna, SK; Natarajan, K1
de Carvalho, MS; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM1
Mijovic, JE; Olson, DM; Zakar, T1
Cobb, RR; Qiu, W; Scholz, W1
Linder, S; Ljungdahl, S; Shoshan, MC; Swedenborg, J; Zhou, JN1
Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H1
Cubillos, S; Lima, L1
Heino, J; Kähäri, VM; Koivisto, L; Nissinen, L; Westermarck, J1
Biswas, T; Boldogh, I; Chen, Z; Grombacher, T; Grösch, S; Hazra, TK; Kaina, B; Mitra, S; Ramana, CV1
Aggarwal, BB; Manna, SK4
Chang, NS; Chang, W; Gelman, MS; Nimnual, AS; Prives, JM; Ross, AF1
Aggarwal, BB; Manna, SK; Ray, R; Shrivastava, A1
Schönthal, AH1
DiGiovanni, J; Higo, R; Iwamori, M; Kagehara, M; Kiguchi, K1
Cillard, J; Okamoto, T; Packer, L; Rihn, B; Saliou, C1
Fabre, S; Georget, V; Lobaccaro, JM; Lumbroso, S; Poujol, N; Sultan, C; Térouanne, B1
Paramio, JM1
Donowitz, M; Kambadur, R; Nath, SK; Tse, CM; Yun, CH1
Breitbart, H; Rubinstein, S; Sun, QY1
Burns, CJ; Howell, SL; Jones, PM; Persaud, SJ1
Fujiki, H; Suganuma, M2
Callahan, KS; Clikeman, JA; Hoidal, JR; Terry, CM1
Chen, CY; Faller, DV1
Beltrán, L; Bol, D; DiGiovanni, J; Kiguchi, K; Rupp, T; Wilker, E1
Bowden, GT; Gupta, A; Rosenberger, SF1
Kishihara, K; Nomoto, K; Sakamoto, T; Wang, B; Zhang, D1
Malaguti, C; Pinna, C; Rossini, GP1
Allis, CD; Bazett-Jones, DP; Chadee, DN; Davie, JR; Hendzel, MJ; Tylipski, CP; Wright, JA1
Dobbelaere, DA; Fernandez, PC1
Fujiki, H; Marino, MW; Okabe, S; Sakai, A; Sueoka, E; Suganuma, M1
Bao, Z; Li, J; Yue, L1
Bartelt, B; Junge, I; Kaufmann, D; Lattke, H; Müller, R1
Aggarwal, BB; Manna, SK; Mukhopadhyay, A; Van, NT1
Anand, M; Manna, PP; Metkar, SS; Nadkarni, JJ; Naresh, KN1
Alcántara-Hernández, R; Gárcia-Sáinz, JA; Vázquez-Prado, J1
Holst, J; Ludowyke, RI; Mudge, LM; Sim, AT1
Bourgeade, MF; Cayre, YE; Thang, MN; Ye, F1
Amsler, K; Henderson, S; Kohanski, RA; Kuze, K; You, G1
Buxbaum, JD; Corfas, G; Peschon, JJ; Rio, C1
Gimenez, MS; Ramirez, DC1
Craig, RW; Domina, AM; Smith, JH1
Aviv, A; Jeanclos, E; Kimura, M; Yang, XY1
Aggarwal, BB; Manna, SK; Mukhopadhyay, A1
Chaudhuri, S; Raha, S1
Bonventre, JV; Gijón, MA; Leslie, CC; Siddiqi, AR; Spencer, DM1
Kajiya, H; Okabe, K; Okamoto, F; Soeda, H; Takada, K1
Eguchi-Kasai, K; Hayata, I; Kanda, R1
Li, T; Lu, L; Reinach, PS1
Balsalobre, A; Marcacci, L; Schibler, U1
Cheng, S; Mao, J; Rehder, V1
Endo, Y; Fukasawa, H; Hashimoto, Y; Shudo, K; Yamaguchi, M1
Browning, MD; Grosshans, DR1
Jang, MA; Kwon, TK; Lee, YH; Park, JW; Passaniti, A1
Crook, RB; Layne, J; Yip, S1
Araneda, RC; Bennett, MV; Grooms, SY; Jover, T; Lan , JY; Lin, Y; Skeberdis, VA; Zheng, X; Zukin, RS1
Chen, DY; Han, ZM; Lu, Q; Schatten, H; Smith, GD; Sun, QY; Yang, Z1
Lee, RG; Rosson, D1
Gimenez, MS; Ramirez, DC; Riera, CM1
Kwon, TK1
Låg, M; Refsnes, M; Schwarze, PE; Thoresen, GH; Thrane, EV1
Baguley, BC; Ching, LM; Philpott, M1
Frankel, SK; Riches, DW; Van Linden, AA1
Kumar, R; Mandal, M; Mazumdar, A; Mishra, SK1
Balaraman, S; Kapoor, P; Madhubala, R; Raj, VS; Saxena, S1
Fujiki, H; Iida, N; Kishimoto, T; Kurusu, M; Ohshima, S; Okabe, S; Saeki, Y; Suganuma, M1
Luo, Z; Ruderman, N; Song, Y; Wen, R; Xiang, X; Yuan, M1
Aggarwal, BB; Lamothe, B; Majumdar, S1
Holst, J; Ludowyke, RI; Sim, AT1
Denys, A; Hichami, A; Khan, NA1
Fan, M; Gaddam, A; Ishaq, M; Natarajan, V; Wigmore, K1
Andrews, DA; Low, PS; Yang, L1
Aggarwal, BB; Ashikawa, K; Banerjee, S; Bharti, AC; Majumdar, S; Shishodia, S1
Bock, PJ; Faulkner, NE; Lane, BR; Markovitz, DM1
Aggarwal, BB; Majumdar, S1
Ghose, AC; Mookerjee, A; Sen, PC1
Göke, B; Groblewski, GE; Krzykowski, KJ; Schäfer, C; Steffen, H1
Fujii, T; Gavrielides, MV; Kazanietz, MG; Mitsuuchi, Y; Tanaka, Y1
Aggarwal, BB; Takada, Y1
Black, JD; Leontieva, OV1
Biden, TJ; Both, GW; Carpenter, L; Mitchell, CJ; Poronnik, P; Xu, ZZ1
Aggarwal, BB; Singh, S; Takada, Y1
Batty, IH; Downes, CP; Fleming, IN1
Biehle, SJ; Clark, JF; Lyons, MA; Pyne, GJ; Shukla, R; Singh, M; Zhang, K1
Mauro, LJ; Warmka, JK; Wattenberg, EV1
Craig, RW; Domina, AM; Gregory, MA; Hann, SR; Vrana, JA1
Aggarwal, BB; Koul, D; Shishodia, S1
Franklin, RA; Howe, CJ; Lahair, MM; McCubrey, JA1
Aggarwal, BB; Shishodia, S1
Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L1
Bełtowski, J; Borkowska, E; Jamroz-Wiśniewska, A; Marciniak, A; Wójcicka, G1
Barth, H; Kinzel, V; Klingler-Hoffmann, M; König, N; Richards, J1
Alcántara-Hernández, R; García-Sáinz, JA1
Aquino, E; Flores, RV; Garrad, RC; Gonzalez, FA; Hernández-Pérez, MG; Weisman, GA1
Bakovic, M; Fullerton, MD; Wagner, L; Yuan, Z1
Joy, KP; Mishra, A1
Ghose, AC; Mukherjee, P; Sen, PC1
Bollinger, J; Cherny, VV; DeCoursey, TE; Finnegan, A; Gelb, MH; Morgan, D1
Chen, JC; Ho, TY; Hsiang, CY; Lee, CH; Wu, HC; Wu, SL1
Beltran, L; Digiovanni, J; Lu, J; Rho, O; Wilker, E1
Gelb, MH; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM; Tucker, DE1
Boyer, B; Drouva, SV; Enjalbert, A; Junoy, B; Maccario, H; Poulin, B; Thirion, S1
Bau, DT; Chen, GW; Chen, JC; Cheng, HM; Ho, TY; Hsiang, CY; Huang, CY; Wu, SL1
Ao, L; Cao, J; Fang, ZJ; Gao, LH; Hu, R; Huang, MH; Liu, JY; Liu, WB; Yang, MS; Zhen, ZX1
Amezcua-Romero, JC; Pantoja, O; Vera-Estrella, R1
Choi, YH; Kim, GY; Kim, WJ; Moon, DO; Moon, SK1
Parra, E1
Craig, RW; Kasof, G; Nifoussi, SK; Ornstein, DL; Ratcliffe, NR; Strack, S1
Attieh, R; Dbaibo, G; El-Hed, AF; Hage-Sleiman, R; Hamze, AB; Kabbani, S; Kozhaya, L1

Reviews

4 review(s) available for tetradecanoylphorbol acetate and okadaic acid

ArticleYear
Okadaic acid--a valuable new tool for the study of signal transduction and cell cycle regulation?
    The New biologist, 1992, Volume: 4, Issue:1

    Topics: Animals; Carcinogens; Cell Cycle; Ethers, Cyclic; Genes, fos; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transformation, Genetic

1992
Role of PP2A in intracellular signal transduction pathways.
    Frontiers in bioscience : a journal and virtual library, 1998, Dec-15, Volume: 3

    Topics: Animals; Genes, Tumor Suppressor; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate

1998
Unique features of the okadaic acid activity class of tumor promoters.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:3-4

    Topics: Animals; Carcinogens; Gene Expression Regulation, Neoplastic; Okadaic Acid; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors.
    Progress in molecular and subcellular biology, 2009, Volume: 46

    Topics: Animals; Carcinogens; Disease Progression; Enzyme Inhibitors; Humans; Marine Toxins; Mice; Models, Molecular; Neoplasms; Neoplasms, Experimental; Okadaic Acid; Oxazoles; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2009

Other Studies

351 other study(ies) available for tetradecanoylphorbol acetate and okadaic acid

ArticleYear
Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells.
    Agents and actions, 1992, Volume: 37, Issue:1-2

    Topics: Animals; Colforsin; Cyclic AMP; Enzyme Activation; Ethers, Cyclic; Histamine Release; In Vitro Techniques; Mast Cells; Okadaic Acid; p-Methoxy-N-methylphenethylamine; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Sodium Fluoride; Tetradecanoylphorbol Acetate

1992
Effects of calyculin A on amylase release in streptolysin-O permeabilized acinar cells.
    Biochemical and biophysical research communications, 1992, Dec-30, Volume: 189, Issue:3

    Topics: Amylases; Animals; Bacterial Proteins; Calcium; Carcinogens; Cell Membrane Permeability; Dose-Response Relationship, Drug; Ethers, Cyclic; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Kinetics; Male; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Rats; Rats, Sprague-Dawley; Streptolysins; Tetradecanoylphorbol Acetate

1992
Synergistic effects of 12-O-tetradecanoylphorbol-13-acetate and dexamethasone on de novo synthesis of histidine decarboxylase in mouse mastocytoma P-815 cells.
    Biochimica et biophysica acta, 1992, Jan-13, Volume: 1133, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Carcinogens; Dexamethasone; Diglycerides; Drug Synergism; Enzyme Activation; Ethers, Cyclic; Histidine Decarboxylase; Isoquinolines; Mast-Cell Sarcoma; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Increased phosphorylation of nuclear phosphoproteins in human lung-cancer cells resistant to cis-diamminedichloroplatinum (II).
    International journal of cancer, 1992, Feb-01, Volume: 50, Issue:3

    Topics: Adenocarcinoma; Cell Nucleus; Cisplatin; Drug Resistance; Electrophoresis, Gel, Two-Dimensional; Ethers, Cyclic; Humans; Lung Neoplasms; Molecular Weight; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1992
Thyrotropin regulates autophosphorylation and kinase activity in both the insulin and the insulin-like growth factor-I receptors in FRTL5 cells.
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Ethers, Cyclic; Fluorides; Insulin-Like Growth Factor I; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

1992
Okadaic acid strongly increases gene transcription, mRNA and protein level for the urokinase receptor in human A549 cells.
    FEBS letters, 1992, Feb-24, Volume: 298, Issue:2-3

    Topics: Blotting, Northern; Cell Line; Ethers, Cyclic; Gene Expression Regulation; Humans; Okadaic Acid; Organ Specificity; Phosphoprotein Phosphatases; Plasminogen Activators; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1992
Effects of antagonists of protein phosphatases on superoxide release by neutrophils.
    The Journal of biological chemistry, 1992, Mar-25, Volume: 267, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Autoradiography; Calcium; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Guinea Pigs; Isoquinolines; Magnesium; Marine Toxins; Models, Biological; Neutrophils; Okadaic Acid; Oxazoles; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Piperazines; Superoxides; Tetradecanoylphorbol Acetate

1992
Tumor necrosis factor alpha-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor.
    The Journal of biological chemistry, 1992, Apr-25, Volume: 267, Issue:12

    Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; DNA; Ethers, Cyclic; Mice; Monosaccharide Transport Proteins; Okadaic Acid; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation

1992
Cell- and gene-specific interactions between signal transduction pathways revealed by okadaic acid. Studies on the plasminogen activating system.
    The Journal of biological chemistry, 1992, Jun-15, Volume: 267, Issue:17

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Ethers, Cyclic; Gene Expression Regulation; Humans; Microbial Collagenase; Okadaic Acid; Phosphoprotein Phosphatases; Plasminogen; Plasminogen Inactivators; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator

1992
Connexin43 in MDCK cells: regulation by a tumor-promoting phorbol ester and Ca2+.
    European journal of cell biology, 1992, Volume: 57, Issue:1

    Topics: Alkaloids; Animals; Calcium; Cell Adhesion; Cell Communication; Cell Membrane Permeability; Cells, Cultured; Connexins; Dogs; Ethers, Cyclic; Immunohistochemistry; Intercellular Junctions; Ionophores; Membrane Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinases; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate

1992
The protein phosphatase inhibitor, okadaic acid, potentiates the stimulatory effect of phorbol ester on phosphatidylcholine synthesis, but not on phospholipid hydrolysis, in fibroblasts.
    FEBS letters, 1992, Aug-24, Volume: 308, Issue:3

    Topics: 3T3 Cells; Animals; Choline; Drug Synergism; Ethers, Cyclic; Fibroblasts; Hydrolysis; Mice; Okadaic Acid; Phosphatidylcholines; Phospholipids; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1992
Enhancement of ganglioside GM3 synthesis in okadaic-acid-treated granulosa cells.
    Biochimica et biophysica acta, 1992, Oct-06, Volume: 1137, Issue:1

    Topics: Animals; Carbohydrate Sequence; Chorionic Gonadotropin; Chromatography, Thin Layer; Colforsin; Cyclic AMP; Down-Regulation; Ethers, Cyclic; Female; Follicle Stimulating Hormone; G(M3) Ganglioside; Granulosa Cells; Molecular Sequence Data; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Receptors, LH; Tetradecanoylphorbol Acetate

1992
The long-term combined stimulatory effects of ethanol and phorbol ester on phosphatidylethanolamine hydrolysis are mediated by a phospholipase C and prevented by overexpressed alpha-protein kinase C in fibroblasts.
    European journal of biochemistry, 1992, Oct-01, Volume: 209, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line; Enzyme Activation; Ethanol; Ethanolamines; Ethers, Cyclic; Fibroblasts; Hydrolysis; Isoenzymes; Isoquinolines; Mice; Mice, Inbred BALB C; Okadaic Acid; Phosphatidylethanolamines; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases

1992
Effects of the protein phosphatase inhibitors okadaic acid and calyculin A on insulin release from rat pancreatic islets.
    Endocrinologia japonica, 1992, Volume: 39, Issue:3

    Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Potassium; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1992
Protein phosphatase inhibitors okadaic acid and calyculin A alter cell shape and F-actin distribution and inhibit stimulus-dependent increases in cytoskeletal actin of human neutrophils.
    Blood, 1992, Dec-01, Volume: 80, Issue:11

    Topics: Actins; Cytoskeleton; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edetic Acid; Ethers, Cyclic; Humans; In Vitro Techniques; Kinetics; Marine Toxins; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pinocytosis; Tetradecanoylphorbol Acetate

1992
Phosphoprotein phosphatase 2A dephosphorylates eIF-4E and does not alter binding to the mRNA cap.
    FEBS letters, 1992, Apr-13, Volume: 301, Issue:1

    Topics: Ethers, Cyclic; Eukaryotic Initiation Factor-4E; Humans; Liver; Models, Biological; Okadaic Acid; Peptide Initiation Factors; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; RNA Caps; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Augmentation of retinoic acid-induced granulocytic differentiation in HL-60 leukemia cells by serine/threonine protein phosphatase inhibitors.
    FEBS letters, 1992, Dec-21, Volume: 314, Issue:3

    Topics: Cell Adhesion; Cell Differentiation; Chromatography, Agarose; Ethers, Cyclic; Granulocytes; Humans; Leukemia; Macrophages; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1992
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida.
    Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida

1992
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
    Journal of assisted reproduction and genetics, 1992, Volume: 9, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate

1992
Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A.
    Biochemical and biophysical research communications, 1992, Dec-30, Volume: 189, Issue:3

    Topics: Antibodies, Monoclonal; Autoradiography; Blotting, Northern; Breast Neoplasms; Caseins; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Female; Fluorescent Antibody Technique; Gene Expression; Genes, fos; Genes, jun; Humans; Isoenzymes; Kinetics; Marine Toxins; Microcystins; Okadaic Acid; Oligonucleotide Probes; Oxazoles; Peptides, Cyclic; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Pyrans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Reduced susceptibility to HIV-1 infection of ethyl-methanesulfonate-treated CEM subclones correlates with a blockade in their protein kinase C signaling pathway.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Jun-15, Volume: 148, Issue:12

    Topics: Base Sequence; CD4-Positive T-Lymphocytes; Cell Compartmentation; Cells, Cultured; Clone Cells; Cytoplasm; DNA-Binding Proteins; Ethers, Cyclic; Ethyl Methanesulfonate; Gene Expression; HIV Infections; HIV Long Terminal Repeat; Humans; In Vitro Techniques; Molecular Sequence Data; Mutation; NF-kappa B; Nuclear Proteins; Okadaic Acid; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate

1992
Effect of TPA, okadaic acid and 1 alpha,25-dihydroxyvitamin D3 on neoplastic transformation induced by 60Co gamma-rays or 252Cf fission neutrons in Balb/c 3T3 cells.
    International journal of radiation biology, 1992, Volume: 61, Issue:2

    Topics: 3T3 Cells; Animals; Calcitriol; Cell Transformation, Neoplastic; Ethers, Cyclic; Gamma Rays; Mice; Mice, Inbred BALB C; Neutrons; Okadaic Acid; Tetradecanoylphorbol Acetate

1992
Okadaic acid mimics multiple changes in early protein phosphorylation and gene expression induced by tumor necrosis factor or interleukin-1.
    The Journal of biological chemistry, 1992, Jan-25, Volume: 267, Issue:3

    Topics: Autoradiography; Blotting, Northern; CDC2 Protein Kinase; Cell Line; DNA-Binding Proteins; Early Growth Response Protein 1; Ethers, Cyclic; Gene Expression; Genes, jun; Humans; Immediate-Early Proteins; Interleukin-1; Interleukin-6; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Recombinant Proteins; RNA; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Necrosis Factor-alpha; Zinc Fingers

1992
Okadaic acid is a potent angiogenesis inducer.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:1

    Topics: Animals; Carcinogens; Chick Embryo; Chorion; Ethers, Cyclic; Neovascularization, Pathologic; Okadaic Acid; Tetradecanoylphorbol Acetate; Time Factors

1992
Protein phosphatase inhibitors and bone resorption: inhibition by okadaic acid and biphasic actions of calyculin-A.
    Endocrinology, 1992, Volume: 130, Issue:6

    Topics: Animals; Animals, Newborn; Autoradiography; Bone and Bones; Bone Resorption; Calcitriol; Calcium; Cyclic AMP; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Kinetics; Marine Toxins; Mice; Mice, Inbred Strains; Okadaic Acid; Organ Culture Techniques; Oxazoles; Parathyroid Hormone; Peptide Fragments; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorus Radioisotopes; Protein Biosynthesis; Protein Phosphatase 1; RNA; Teriparatide; Tetradecanoylphorbol Acetate

1992
Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells.
    Molecular pharmacology, 1992, Volume: 41, Issue:6

    Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance; Ethers, Cyclic; Humans; KB Cells; Membrane Glycoproteins; Naphthalenes; Okadaic Acid; Peptide Mapping; Phenotype; Phospholipid Ethers; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vinblastine

1992
Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine.
    The Journal of biological chemistry, 1992, Nov-25, Volume: 267, Issue:33

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cell Division; Cell Line; Ceramides; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Humans; Ionomycin; Isomerism; Isoquinolines; Molecular Weight; Naphthalenes; Okadaic Acid; Phosphorylation; Piperazines; Polycyclic Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase C; Retinoblastoma Protein; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate

1992
Differential inhibition by staurosporine of phorbol ester, bryostatin and okadaic acid effects on mouse skin.
    Cancer letters, 1992, Sep-30, Volume: 66, Issue:2

    Topics: Alkaloids; Animals; Bryostatins; Cyclosporine; Edema; Ethers, Cyclic; Female; Lactones; Macrolides; Mice; Okadaic Acid; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate

1992
Pathological phosphorylation causes neuronal death: effect of okadaic acid in primary culture of cerebellar granule cells.
    Journal of neurochemistry, 1992, Volume: 59, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Death; Cells, Cultured; Cerebellum; Ethers, Cyclic; Granulocytes; Isoquinolines; Neurons; Okadaic Acid; Phosphorylation; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1992
Regulation of c-jun expression during induction of monocytic differentiation by okadaic acid.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1992, Volume: 3, Issue:7

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Ethers, Cyclic; Gene Expression Regulation, Leukemic; Genes, jun; Humans; Isoquinolines; Lymphoma, Large B-Cell, Diffuse; Male; Monocytes; Neoplasm Proteins; Neoplastic Stem Cells; Okadaic Acid; Piperazines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1992
Regulation of phospholipase D by sphingosine involves both protein kinase C-dependent and -independent mechanisms in NIH 3T3 fibroblasts.
    The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3)

    Topics: 3T3 Cells; Alkaloids; Animals; Bryostatins; Down-Regulation; Drug Interactions; Ethers, Cyclic; Hydrolysis; Lactones; Macrolides; Mice; Okadaic Acid; Phosphatidylethanolamines; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Protein Kinase C; Sphingomyelin Phosphodiesterase; Sphingosine; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1992
Nonphorbol tumor promoters okadaic acid and calyculin-A induce membrane translocation of protein kinase C.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cytosol; Ethers, Cyclic; Immunoblotting; Kidney; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1992
Mitotic arrest and enhanced nuclear protein phosphorylation in human leukemia K562 cells by okadaic acid, a potent protein phosphatase inhibitor and tumor promoter.
    The Journal of biological chemistry, 1991, Jun-05, Volume: 266, Issue:16

    Topics: Autoradiography; Carcinogens; Colchicine; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Humans; Leukemia; Mitosis; Nuclear Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1991
Effects of okadaic acid on agonist-stimulated PGI2 production by rat liver cells (the C-9 cell line).
    Prostaglandins, 1991, Volume: 41, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Ethers, Cyclic; Kinetics; Liver; Okadaic Acid; Phosphoprotein Phosphatases; Platelet Activating Factor; Prostaglandins F; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Thrombin

1991
Protein phosphorylation and dephosphorylation in type II pneumocytes.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Animals; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Ethers, Cyclic; Kinetics; Lung; Male; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protamines; Proteins; Pulmonary Surfactants; Rats; Tetradecanoylphorbol Acetate

1991
The Na+/H+ exchanger is phosphorylated in human platelets in response to activating agents.
    FEBS letters, 1991, Jun-24, Volume: 284, Issue:2

    Topics: Alkaloids; Blood Platelets; Carrier Proteins; Diglycerides; Ethers, Cyclic; Humans; Hydrogen-Ion Concentration; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin

1991
Modulation of Na+/H+ exchange and intracellular pH by protein kinase C and protein phosphatase in blood platelets.
    Biochimica et biophysica acta, 1991, Sep-30, Volume: 1068, Issue:2

    Topics: Alkaloids; Blood Platelets; Carrier Proteins; Cytoplasm; Diglycerides; Ethers, Cyclic; Fluoresceins; Humans; Hydrogen-Ion Concentration; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate

1991
Okadaic acid-induced hyperphosphorylation of the epidermal growth factor receptor. Comparison with receptor phosphorylation and functions affected by another tumor promoter, 12-O-tetradecanoylphorbol-13-acetate.
    The Journal of biological chemistry, 1991, Nov-05, Volume: 266, Issue:31

    Topics: Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Ethers, Cyclic; Humans; In Vitro Techniques; Okadaic Acid; Peptide Mapping; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases

1991
Regulation of the transmodulated epidermal growth factor receptor by cholera toxin and the protein phosphatase inhibitor okadaic acid.
    Journal of cellular biochemistry, 1991, Volume: 47, Issue:1

    Topics: Animals; Cells, Cultured; Cholera Toxin; Cyclic AMP; Epidermal Growth Factor; ErbB Receptors; Ethers, Cyclic; Kinetics; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Tetradecanoylphorbol Acetate

1991
Differential regulation of jun family gene expression by the tumor promoter okadaic acid.
    The New biologist, 1991, Volume: 3, Issue:10

    Topics: 3T3 Cells; Animals; Base Sequence; Carcinogens; DNA-Binding Proteins; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Mice; Microbial Collagenase; Molecular Sequence Data; Multigene Family; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate

1991
Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Aug-01, Volume: 147, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Interleukin-1; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1991
Pleiotropic effect of okadaic acid on maturing mouse oocytes.
    Development (Cambridge, England), 1991, Volume: 112, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Cells, Cultured; Cytoskeleton; Ethers, Cyclic; Fluorescent Antibody Technique; Meiosis; Mesothelin; Mice; Microtubules; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1991
Control of nucleoside transport in neural cells. Effect of protein kinase C activation.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adrenal Medulla; Animals; Biological Transport; Calcimycin; Caprylates; Cells, Cultured; Diglycerides; Dinucleoside Phosphates; Enzyme Activation; Ethers, Cyclic; Isoquinolines; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Triglycerides

1991
Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line.
    Blood, 1991, Jan-15, Volume: 77, Issue:2

    Topics: Cell Line; Ethers, Cyclic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interleukin-3; Okadaic Acid; Phosphorylation; Phosphoserine; Precipitin Tests; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Vanadates

1991
Okadaic acid induction of the urokinase-type plasminogen activator gene occurs independently of cAMP-dependent protein kinase and protein kinase C and is sensitive to protein synthesis inhibition.
    The EMBO journal, 1991, Volume: 10, Issue:1

    Topics: Animals; Cell Line; Enzyme Induction; Ethers, Cyclic; Kinetics; Okadaic Acid; Phosphoprotein Phosphatases; Plasminogen Activators; Protein Kinase C; Protein Kinases; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator

1991
Differential genomic susceptibility in malignancy correlates with changes in ATATAT DNA-binding proteins.
    Biochemical and biophysical research communications, 1991, Aug-15, Volume: 178, Issue:3

    Topics: Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; DNA-Binding Proteins; Embryo, Mammalian; Ethers, Cyclic; Genetic Predisposition to Disease; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nuclear Proteins; Okadaic Acid; Substrate Specificity; Tetradecanoylphorbol Acetate

1991
Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2.
    The Biochemical journal, 1991, Mar-01, Volume: 274 ( Pt 2)

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Ethers, Cyclic; Glucagon; GTP-Binding Proteins; Ionophores; Kinetics; Liver; Macromolecular Substances; Male; Okadaic Acid; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins

1991
Phosphorylation-dependent regulation of axon fasciculation.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Dec-01, Volume: 88, Issue:23

    Topics: Animals; Axons; Cell Adhesion Molecules, Neuronal; Chick Embryo; Culture Techniques; Ethers, Cyclic; Immunoglobulin Fab Fragments; Neurites; Okadaic Acid; Phosphorylation; Retina; Retinal Ganglion Cells; Tetradecanoylphorbol Acetate

1991
Activation of messenger-independent protein kinases in wild-type and phorbol ester-resistant EL4 thymoma cells.
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Ethers, Cyclic; Glycogen Synthase Kinase 3; Isoquinolines; Mice; Molecular Sequence Data; Okadaic Acid; Oligopeptides; Phosphoproteins; Piperazines; Protein Kinase C; Protein Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured

1991
Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors.
    Cell, 1991, May-31, Volume: 65, Issue:5

    Topics: Amanitins; Amino Acid Sequence; Animals; Anisomycin; Cell Line; Chromatin; Cycloheximide; Dactinomycin; Ethers, Cyclic; Growth Substances; Histones; Mice; Mice, Inbred C3H; Molecular Sequence Data; Nucleosomes; Okadaic Acid; Phosphates; Phosphopeptides; Phosphorylation; Protein Synthesis Inhibitors; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic

1991
Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells.
    The Journal of biological chemistry, 1991, Jul-05, Volume: 266, Issue:19

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Differentiation; Cycloheximide; DNA; Ethers, Cyclic; Humans; Macrophages; Molecular Sequence Data; Okadaic Acid; Phosphorylation; RNA, Messenger; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured

1991
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:15

    Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Cell Line; Ethers, Cyclic; Humans; Kinetics; Methionine; Molecular Weight; Okadaic Acid; Pheochromocytoma; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Protein Precursors; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Transcription, Genetic

1990
Evidence for protein dephosphorylation as a permissive step in GTP-gamma-S-induced exocytosis from permeabilized mast cells.
    Cell regulation, 1990, Volume: 1, Issue:7

    Topics: Adenosine Triphosphate; Animals; Calcium; Ethers, Cyclic; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Male; Mast Cells; Okadaic Acid; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1990
Induction of nuclear factor-kappa B and the human immunodeficiency virus long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A.
    The New biologist, 1990, Volume: 2, Issue:9

    Topics: Cell Line; Ethers, Cyclic; Gene Expression Regulation; HIV Long Terminal Repeat; Humans; NF-kappa B; Okadaic Acid; Phosphoprotein Phosphatases; Phytohemagglutinins; Tetradecanoylphorbol Acetate

1990
Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin.
    British journal of cancer, 1990, Volume: 62, Issue:3

    Topics: Cell Division; Cell Line; Chemical Phenomena; Chemistry; Cisplatin; Cross Reactions; Doxorubicin; Drug Resistance; Ethers, Cyclic; Humans; Leukemia, Myeloid; Lung Neoplasms; Lyngbya Toxins; Okadaic Acid; Tetradecanoylphorbol Acetate

1990
Increased rate of phosphorylation-dephosphorylation of the translational initiation factor eIF-4E correlates with the induction of protein and glycoprotein biosynthesis in activated B lymphocytes.
    The Journal of biological chemistry, 1990, Nov-15, Volume: 265, Issue:32

    Topics: Animals; B-Lymphocytes; Ethers, Cyclic; Eukaryotic Initiation Factor-4E; Female; Glycoproteins; Half-Life; Ionomycin; Kinetics; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred DBA; Okadaic Acid; Peptide Initiation Factors; Phosphates; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Spleen; Tetradecanoylphorbol Acetate

1990
The non-phorbol ester tumor promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells.
    Biochemical and biophysical research communications, 1990, Mar-30, Volume: 167, Issue:3

    Topics: Animals; Carcinogens; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Ethers, Cyclic; Intercellular Junctions; Mesocricetus; Okadaic Acid; Tetradecanoylphorbol Acetate

1990
Permeability of a non-TPA-type tumor promoter, okadaic acid, through lipid bilayer membrane.
    Carcinogenesis, 1990, Volume: 11, Issue:7

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Buffers; Cell Membrane Permeability; Ethers, Cyclic; Fluoresceins; Membrane Fluidity; Membrane Lipids; Okadaic Acid; Spectrum Analysis; Tetradecanoylphorbol Acetate

1990
Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages.
    Biochimica et biophysica acta, 1989, Sep-04, Volume: 1013, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Dinoprostone; Ethers, Cyclic; Ionophores; Kinetics; Macrophages; Marine Toxins; Okadaic Acid; Pyrans; Rats; Tetradecanoylphorbol Acetate

1989
A type 2A protein phosphatase dephosphorylates the elongation factor 2 and is stimulated by the phorbol ester TPA in mouse epidermis in vivo.
    FEBS letters, 1989, Nov-06, Volume: 257, Issue:2

    Topics: Animals; Cytosol; Enzyme Activation; Epidermis; Ethers, Cyclic; Heparin; Mice; Molecular Weight; Okadaic Acid; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Tetradecanoylphorbol Acetate

1989
Diversity in the chemical nature and mechanism of response to tumor promoters.
    Progress in clinical and biological research, 1989, Volume: 298

    Topics: Acrylamides; Alkaloids; Animals; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Cnidarian Venoms; Enzyme Induction; Ethers, Cyclic; Mice; Okadaic Acid; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoconstrictor Agents

1989
Flat reversion by okadaic acid of raf and ret-II transformants.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:24

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Fibronectins; Fluorescent Antibody Technique; Genes, ras; Ionophores; Kinetics; Mice; Okadaic Acid; Oncogenes; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection

1989
The tumor promoters 12-O-tetradecanoylphorbol-13-acetate and okadaic acid differ in toxicity, mitogenic activity and induction of gene expression.
    Carcinogenesis, 1989, Volume: 10, Issue:8

    Topics: Animals; Carcinogens; Cell Survival; Cells, Cultured; DNA Replication; Ethers, Cyclic; Gene Expression Regulation; Kinetics; Mice; Okadaic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine; Transcription, Genetic; Transcriptional Activation

1989
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Enzyme Induction; Ethers, Cyclic; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Porifera; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Hyperphosphorylation of N-60, a protein structurally and immunologically related to nucleolin after tumour-promoter treatment.
    The EMBO journal, 1988, Volume: 7, Issue:6

    Topics: Carcinogens; Cross Reactions; Ethers, Cyclic; Fibroblasts; Humans; Lyngbya Toxins; Nuclear Proteins; Nucleolin; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proteins; RNA-Binding Proteins; Tetradecanoylphorbol Acetate; Tretinoin

1988
Preferential requirement for protein tyrosine phosphatase activity in the 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human colon cancer cells.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Cell Differentiation; Chlorides; Colonic Neoplasms; Enzyme Activation; Ethers, Cyclic; Genistein; Humans; Isoflavones; Okadaic Acid; Protein Tyrosine Phosphatases; Proteoglycans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc Compounds

1995
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:12

    Topics: Apoptosis; Calcimycin; Cell Cycle; Cell Survival; Child, Preschool; Cholera Toxin; Colforsin; DNA, Neoplasm; Enzyme Inhibitors; Ethers, Cyclic; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Male; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Retinoblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1995
Protein kinase C activation precedes arachidonic acid release during IgG-mediated phagocytosis.
    Journal of immunology (Baltimore, Md. : 1950), 1995, Dec-15, Volume: 155, Issue:12

    Topics: Arachidonic Acid; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Humans; Immunoglobulin G; Intercellular Signaling Peptides and Proteins; Melitten; Monocytes; Okadaic Acid; Peptides; Phagocytosis; Phospholipases A; Phospholipases A2; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Time Factors; Wasp Venoms

1995
Dynamic state of beta 2 integrin phosphorylation: regulation of neutrophil aggregation involves a phosphatase-dependent pathway.
    Clinical immunology and immunopathology, 1994, Volume: 71, Issue:2

    Topics: Adult; Amino Acid Sequence; Antigens, CD; CD18 Antigens; Cell Aggregation; Cell Survival; Ethers, Cyclic; Humans; Integrins; Kinetics; L-Lactate Dehydrogenase; Macromolecular Substances; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate

1994
Phosphorylation of Gi alpha 2 attenuates inhibitory adenylyl cyclase in neuroblastoma/glioma hybrid (NG-108-15) cells.
    The Journal of biological chemistry, 1994, May-13, Volume: 269, Issue:19

    Topics: Adenylyl Cyclases; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Ethers, Cyclic; Glioma; GTP-Binding Proteins; Hybrid Cells; Naphthalenes; Neuroblastoma; Okadaic Acid; Phorbols; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Calyculin A, okadaic acid and W-7 interfere with a distal step in pancreatic acinar signal transduction.
    Biochemical and biophysical research communications, 1994, Jun-30, Volume: 201, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Calcium; Cyclic AMP; Ethers, Cyclic; Inositol 1,4,5-Trisphosphate; Male; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Rats; Rats, Wistar; Secretory Rate; Signal Transduction; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoactive Intestinal Peptide

1994
Multiple mitogenic signalling pathways in chromaffin cells: a model for cell cycle regulation in the nervous system.
    Neuroscience letters, 1994, Feb-28, Volume: 168, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Cell Cycle; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Models, Neurological; Nerve Endings; Nerve Growth Factors; Okadaic Acid; Phosphoprotein Phosphatases; Potassium Chloride; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrodotoxin; Veratridine

1994
Study of the activation mechanism of adriamycin on rat mast cells.
    Agents and actions, 1994, Volume: 42, Issue:3-4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Antimycin A; Benzalkonium Compounds; Calcium; Cells, Cultured; Cholera Toxin; Doxorubicin; Ethers, Cyclic; Histamine Release; In Vitro Techniques; Mast Cells; Okadaic Acid; Peritoneal Cavity; Pertussis Toxin; Pleura; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Trifluoperazine; Virulence Factors, Bordetella

1994
Protein kinases and phosphatases modulate c-fos expression in rat hepatocytes. Effects of angiotensin II and phorbol myristate acetate.
    Life sciences, 1995, Volume: 56, Issue:10

    Topics: Alkaloids; Angiotensin II; Animals; Ethers, Cyclic; Female; Gene Expression; Genes, fos; Genistein; Isoflavones; Marine Toxins; Microcystins; Naphthalenes; Okadaic Acid; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

1995
The MEK kinase activity of the catalytic domain of RAF-1 is regulated independently of Ras binding in T cells.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Binding Sites; Cell Line; Enzyme Activation; Epitopes; Ethers, Cyclic; Hemagglutinins; Humans; MAP Kinase Kinase Kinase 1; Marine Toxins; Mice; Molecular Sequence Data; Okadaic Acid; Oligopeptides; Oxazoles; Phosphoprotein Phosphatases; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Receptor-CD3 Complex, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
The mitogen-activated protein kinase cascade in rat islets of Langerhans.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Ethers, Cyclic; Glucose; Islets of Langerhans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates

1995
Inhibition of serine/threonine protein phosphatases enhances agonist-stimulated cAMP accumulation in UMR 106 osteoblast-like cells.
    Molecular and cellular endocrinology, 1995, Apr-28, Volume: 110, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Antifungal Agents; Colforsin; Cyclic AMP; Dinoprostone; Ethers, Cyclic; Humans; Kinetics; Marine Toxins; Okadaic Acid; Osteoblasts; Oxazoles; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Serine-Threonine Kinases; Proteins; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-10, Volume: 92, Issue:21

    Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Colforsin; Cytoplasm; Enzyme Inhibitors; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Membranes; Mice; Mice, Obese; Okadaic Acid; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioimmunoassay; Tetradecanoylphorbol Acetate

1995
Inhibitory effects of cadmium ion on extracellular Ca(2+)-independent contraction of rat aorta.
    European journal of pharmacology, 1995, Jul-01, Volume: 293, Issue:2

    Topics: Animals; Aorta, Thoracic; Cadmium; Calcium; Ethers, Cyclic; Extracellular Space; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Okadaic Acid; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Sodium Fluoride; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents

1995
A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jul-03, Volume: 92, Issue:14

    Topics: Animals; Cell Line; Cell Nucleus; Chromatin; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; ErbB Receptors; Ethers, Cyclic; Growth Substances; Ligands; Mice; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Receptor, ErbB-2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha

1995
Somatostatin inhibits AP-1 function via multiple protein phosphatases.
    The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1

    Topics: Animals; Base Sequence; Cell Division; Ethers, Cyclic; Molecular Probes; Molecular Sequence Data; Octreotide; Okadaic Acid; Pertussis Toxin; Phosphoprotein Phosphatases; Rats; Receptors, Somatostatin; Somatostatin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured; Vanadates; Virulence Factors, Bordetella

1995
Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:5

    Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Cell Division; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Epithelium; Ethers, Cyclic; Gene Expression Regulation; Immediate-Early Proteins; In Situ Hybridization; Intestinal Mucosa; Male; Molecular Sequence Data; Okadaic Acid; Protein Biosynthesis; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transforming Growth Factor alpha; Tristetraprolin; Zinc Fingers

1995
Involvement of protein phosphatases in gonadotropin releasing hormone regulated gonadotropin secretion.
    Molecular and cellular endocrinology, 1995, Apr-28, Volume: 111, Issue:1

    Topics: Animals; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Female; Gonadotropin-Releasing Hormone; Ionomycin; Luteinizing Hormone; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Pituitary Gland; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1995
Inhibition of deoxygenation-induced membrane protein dephosphorylation and cell dehydration by phorbol esters and okadaic acid in sickle cells.
    Blood, 1995, Sep-01, Volume: 86, Issue:5

    Topics: Adenosine Triphosphate; Anemia, Sickle Cell; Biological Transport; Calcium; Calcium-Transporting ATPases; Desiccation; Erythrocyte Membrane; Erythrocytes; Ethers, Cyclic; Humans; In Vitro Techniques; Kinetics; Membrane Proteins; Okadaic Acid; Oxygen; Phosphates; Phosphorus Radioisotopes; Potassium; Protein Kinase C; Protein Tyrosine Phosphatases; Reference Values; Sodium; Tetradecanoylphorbol Acetate

1995
Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways.
    Blood, 1995, Sep-15, Volume: 86, Issue:6

    Topics: Actins; Animals; Cations, Divalent; Cell Adhesion; Cytoskeleton; Dithiothreitol; Ethers, Cyclic; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Marine Toxins; Membrane Proteins; Mice; Naphthalenes; Neoplasm Proteins; Okadaic Acid; Oxazoles; Oxidation-Reduction; Phosphoprotein Phosphatases; Phosphorylation; Protein Conformation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, IgG; Signal Transduction; Structure-Activity Relationship; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Role of LFB3 in cell-specific cAMP induction of the urokinase-type plasminogen activator gene.
    The Journal of biological chemistry, 1995, Sep-15, Volume: 270, Issue:37

    Topics: Animals; Base Sequence; Binding Sites; Cell Line; Colchicine; Cyclic AMP; Cytochalasin B; DNA-Binding Proteins; Enzyme Induction; Ethers, Cyclic; Feedback; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1-beta; Kidney; Luciferases; Mice; Molecular Sequence Data; Okadaic Acid; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; Signal Transduction; TATA Box; Templates, Genetic; Teratocarcinoma; Tetradecanoylphorbol Acetate; Thymidine Kinase; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1995
Biochemical characterization of human GCF transcription factor in tumor cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:6

    Topics: 3T3 Cells; Animals; Cell Line, Transformed; Chlorocebus aethiops; Cyclic AMP; DNA, Complementary; Down-Regulation; ErbB Receptors; Ethers, Cyclic; Fibroblasts; Humans; Immune Sera; Mice; Molecular Weight; Okadaic Acid; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Rabbits; Recombinant Fusion Proteins; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
GM-CSF triggers a rapid, glucose dependent extracellular acidification by TF-1 cells: evidence for sodium/proton antiporter and PKC mediated activation of acid production.
    Journal of cellular physiology, 1993, Volume: 154, Issue:1

    Topics: Benzoquinones; Bone Marrow; Bone Marrow Cells; Carrier Proteins; Cell Division; Cell Line; Ethers, Cyclic; Genistein; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1993
Regulation of the TNF-alpha receptor in human osteosarcoma cells: role of microtubules and of protein kinase C.
    Archives of biochemistry and biophysics, 1993, Volume: 300, Issue:1

    Topics: Alkaloids; Cell Membrane; Cycloheximide; Ethers, Cyclic; Humans; Kinetics; Microtubules; Naphthalenes; Okadaic Acid; Osteosarcoma; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine

1993
Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Bucladesine; Calcimycin; Colforsin; Colonic Neoplasms; DNA Probes; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Ionomycin; Ionophores; Kinetics; Mucins; Okadaic Acid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1993
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
    Experimental cell research, 1993, Volume: 207, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc

1993
Modulation of cell signaling pathways can enhance or impair glucocorticoid-induced gene expression without altering the state of receptor phosphorylation.
    The Journal of biological chemistry, 1993, Oct-25, Volume: 268, Issue:30

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Luciferases; Mammary Tumor Virus, Mouse; Okadaic Acid; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Receptors, Glucocorticoid; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1993
Okadaic acid potentiates heat-induced activation of erk2.
    Biochimica et biophysica acta, 1995, Mar-16, Volume: 1265, Issue:2-3

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Ethers, Cyclic; HeLa Cells; Hot Temperature; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphorylation; Tetradecanoylphorbol Acetate

1995
Okadaic acid increased annexin I and induced differentiation of human promyelocytic leukemia cells.
    Biochimica et biophysica acta, 1995, Apr-06, Volume: 1266, Issue:1

    Topics: Annexin A1; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Ethers, Cyclic; Humans; Leukemia, Myeloid; Okadaic Acid; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate

1995
Contrasting effects of calyculin A and okadaic acid on the respiratory burst of human neutrophils.
    European journal of pharmacology, 1995, Jan-16, Volume: 288, Issue:2

    Topics: Amino Acid Sequence; Calcimycin; Ethers, Cyclic; Humans; In Vitro Techniques; Marine Toxins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate

1995
Suppression of elastin gene expression in dermal fibroblasts by protein phosphatase inhibitor okadaic acid.
    Biochemical and biophysical research communications, 1995, Apr-06, Volume: 209, Issue:1

    Topics: Adult; Animals; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Elastin; Ethers, Cyclic; Gene Expression Regulation; Humans; Male; Mice; Mice, Transgenic; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tretinoin

1995
Elevation of transforming growth factor-alpha mRNA and protein expression by diverse tumor promoters in SENCAR mouse epidermis.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:4

    Topics: Administration, Topical; Animals; Anthracenes; Base Sequence; Blotting, Northern; Carcinogens; DNA Primers; Ethers, Cyclic; Female; Fluorescent Antibody Technique; Gene Expression; Mice; Mice, Inbred SENCAR; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; RNA, Messenger; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transforming Growth Factor alpha

1995
Effects of okadaic acid and vanadate on TPA-induced monocytic differentiation in human promyelocytic leukemia cell line HL-60.
    Cancer letters, 1995, Apr-14, Volume: 90, Issue:2

    Topics: Cell Differentiation; Ethers, Cyclic; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Promyelocytic, Acute; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates

1995
Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.
    The Journal of biological chemistry, 1995, May-05, Volume: 270, Issue:18

    Topics: Adenosine Triphosphate; Arsenicals; Base Sequence; Ceramides; Diamide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Ethers, Cyclic; Humans; I-kappa B Proteins; In Vitro Techniques; Interleukin-1; Marine Toxins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligodeoxyribonucleotides; Oxazoles; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vanadates

1995
Effects of stimulators of protein kinases A and C and modulators of phosphorylation on plasminogen activator activity in porcine oocyte-cumulus cell complexes during in vitro maturation.
    Molecular reproduction and development, 1995, Volume: 40, Issue:3

    Topics: Adenine; Animals; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Ethers, Cyclic; Female; In Vitro Techniques; Okadaic Acid; Oocytes; Oogenesis; Phosphorylation; Plasminogen Activators; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate

1995
Effects of okadaic acid on calcitriol- and phorbol ester-induced expression and phosphorylation of osteopontin in mouse JB6 epidermal cells.
    Annals of the New York Academy of Sciences, 1995, Apr-21, Volume: 760

    Topics: Animals; Calcitriol; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethers, Cyclic; Gene Expression; In Vitro Techniques; Mice; Okadaic Acid; Osteopontin; Phosphoproteins; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate

1995
Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli.
    The EMBO journal, 1995, Jun-15, Volume: 14, Issue:12

    Topics: Base Sequence; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligopeptides; Phosphoprotein Phosphatases; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Serine; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Necrosis Factor-alpha

1995
Differential induction of apoptosis in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:9

    Topics: Apoptosis; Breast Neoplasms; Electrophoresis; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
1,25-Dihydroxyvitamin D3 stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: an effect modulated by vitamin D status.
    Journal of cellular physiology, 1995, Volume: 162, Issue:2

    Topics: Animals; Calcitriol; Cells, Cultured; Colon; Ethers, Cyclic; Isoelectric Point; Kinetics; Male; Membrane Proteins; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1995
Modulation of Ca(2+)-channel currents by protein kinase C in adult rat sympathetic neurons.
    Journal of neurophysiology, 1994, Volume: 72, Issue:4

    Topics: Animals; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Enzyme Activation; Ethers, Cyclic; GTP-Binding Proteins; Membrane Potentials; Neural Inhibition; Neurons; Okadaic Acid; Patch-Clamp Techniques; Pertussis Toxin; Protein Kinase C; Rats; Superior Cervical Ganglion; Synaptic Transmission; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1994
Okadaic acid-elicited transcriptional activation of collagenase gene expression in HT-1080 fibrosarcoma cells is mediated by JunB.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:11

    Topics: Collagenases; Dexamethasone; Enzyme Induction; Ethers, Cyclic; Fibrosarcoma; Glycoproteins; Humans; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Neoplasm Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Transcription Factor AP-1; Transcriptional Activation; Tumor Cells, Cultured

1994
Okadaic acid increases nerve growth factor secretion, mRNA stability, and gene transcription in primary cultures of cortical astrocytes.
    The Journal of biological chemistry, 1995, Mar-17, Volume: 270, Issue:11

    Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Cell Nucleus; Cells, Cultured; Cerebral Cortex; DNA Probes; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Gene Expression; Genes, fos; Genes, jun; Kinetics; Marine Toxins; Nerve Growth Factors; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic

1995
Okadaic acid Co-induces vimentin expression and cell cycle arrest in MPC-11 mouse plasmacytoma cells.
    Journal of cellular physiology, 1995, Volume: 163, Issue:1

    Topics: Animals; Carcinogens; Cell Cycle; Ethers, Cyclic; Fluorescent Antibody Technique; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Okadaic Acid; Plasmacytoma; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin

1995
Regulation of CD18 expression in human neutrophils as related to shape changes.
    Journal of cell science, 1993, Volume: 106 ( Pt 2)

    Topics: Amino Acid Sequence; Antigens, CD; CD18 Antigens; Cell Movement; Cell Size; Chemotactic Factors; Ethers, Cyclic; Humans; In Vitro Techniques; Indoles; Marine Toxins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oligopeptides; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate

1993
Collagen gel contraction induced by retinal pigment epithelial cells and choroidal fibroblasts involves the protein kinase C pathway.
    Current eye research, 1994, Volume: 13, Issue:6

    Topics: Animals; Cattle; Cells, Cultured; Choroid; Collagen; Epithelium; Ethers, Cyclic; Gels; Okadaic Acid; Phosphorylation; Pigment Epithelium of Eye; Protein Kinase C; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1994
Stimulation of androgen-regulated transactivation by modulators of protein phosphorylation.
    Endocrinology, 1994, Volume: 135, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androgen Antagonists; Androgens; Anilides; Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Ethers, Cyclic; HeLa Cells; Humans; Molecular Sequence Data; Nitriles; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Receptors, Androgen; Testosterone; Tetradecanoylphorbol Acetate; Tosyl Compounds; Transcriptional Activation

1994
Activation of the mouse IL-2 gene by okadaic acid: synergy with interleukin-1.
    Lymphokine and cytokine research, 1994, Volume: 13, Issue:3

    Topics: Animals; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Interleukin-1; Interleukin-2; Interleukin-6; Mice; Neoplasm Proteins; Okadaic Acid; Phosphoprotein Phosphatases; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured

1994
Okadaic acid reverses the inhibitory effect of protein kinase C on alkaline phosphatase activity in osteoblast-like cells.
    Molecular and cellular endocrinology, 1994, Volume: 103, Issue:1-2

    Topics: Alkaline Phosphatase; Cell Line; Culture Media; Ethers, Cyclic; Fetal Blood; Okadaic Acid; Osteoblasts; Protein Kinase C; Tetradecanoylphorbol Acetate

1994
Carbachol-stimulated phosphorylation of the Na-K-Cl cotransporter of avian salt gland. Requirement for Ca2+ and PKC Activation.
    The Journal of biological chemistry, 1994, Nov-25, Volume: 269, Issue:47

    Topics: Animals; Birds; Calcium; Carbachol; Carrier Proteins; Chlorides; Enzyme Activation; Ethers, Cyclic; Ionomycin; Okadaic Acid; Phosphorylation; Potassium; Precipitin Tests; Protein Kinase C; Salt Gland; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate

1994
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
    The Journal of cell biology, 1994, Volume: 127, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

1994
Regulated internalization of caveolae.
    The Journal of cell biology, 1994, Volume: 127, Issue:5

    Topics: Alkaline Phosphatase; Alkaloids; Animals; Biological Transport; Caveolin 1; Caveolins; Cell Line; Cell Membrane; Cytochalasin D; Ethers, Cyclic; Genistein; Hypertonic Solutions; Isoflavones; Membrane Proteins; Microscopy, Electron; Microtubules; Nocodazole; Okadaic Acid; Staurosporine; Tetradecanoylphorbol Acetate

1994
Comparison of the effects of insulin and okadaic acid on phosphoenolpyruvate carboxykinase gene expression.
    The Biochemical journal, 1994, Nov-01, Volume: 303 ( Pt 3)

    Topics: Animals; Base Sequence; Dexamethasone; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Okadaic Acid; Oligodeoxyribonucleotides; Phosphoenolpyruvate Carboxykinase (GTP); Phosphoproteins; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
Intracellular mediators of goblet cell degranulation in isolated pancreatic ducts.
    Biochemical and biophysical research communications, 1994, Nov-30, Volume: 205, Issue:1

    Topics: Animals; Calcimycin; Carbachol; Cell Degranulation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Ethers, Cyclic; Guinea Pigs; In Vitro Techniques; Male; Nocodazole; Okadaic Acid; Pancreatic Ducts; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide

1994
Loss of mouse epidermal protein kinase C isozyme activities following treatment with phorbol ester and non-phorbol ester tumor promoters.
    Carcinogenesis, 1994, Volume: 15, Issue:12

    Topics: Animals; Anthracenes; Biological Transport; Carcinogens; Cytosol; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Ethers, Cyclic; Female; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred SENCAR; Okadaic Acid; Protein Kinase C; Tetradecanoylphorbol Acetate

1994
Activation of early growth response 1 gene transcription and pp90rsk during induction of monocytic differentiation.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:3

    Topics: Cell Differentiation; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation; Humans; Immediate-Early Proteins; Monocytes; Okadaic Acid; Phenotype; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

1994
Tumor-promoting phorbol ester transiently down-modulates the p53 level and blocks the cell cycle.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:3

    Topics: Cell Cycle; Cycloheximide; Down-Regulation; Ethers, Cyclic; Half-Life; Humans; Okadaic Acid; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1994
Transforming growth factor beta 1 inhibits interleukin-1-induced but enhances ionomycin-induced interferon-gamma production in a T cell lymphoma: comparison with the effects of rapamycin.
    Journal of cellular physiology, 1994, Volume: 160, Issue:1

    Topics: Animals; Cell Division; Drug Interactions; Drug Synergism; Ethers, Cyclic; Immunosuppressive Agents; Interferon-gamma; Interleukin-1; Ionomycin; Lymphoma, T-Cell; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; RNA, Messenger; Sirolimus; Swine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

1994
Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Macrophages, Peritoneal; Maleimides; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Zymosan

1994
Phorbol ester administration transiently increases aromatic L-amino acid decarboxylase activity of the mouse striatum and midbrain.
    Journal of neurochemistry, 1994, Volume: 63, Issue:2

    Topics: Alkaloids; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benzophenanthridines; Cerebral Ventricles; Corpus Striatum; Ethers, Cyclic; Injections, Intraventricular; Kinetics; Levodopa; Male; Mesencephalon; Mice; Okadaic Acid; Phenanthridines; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Pyridoxal Phosphate; Reference Values; Regression Analysis; Tetradecanoylphorbol Acetate

1994
Induction of manganese superoxide dismutase mRNA by okadaic acid and protein synthesis inhibitors.
    The Biochemical journal, 1994, Jul-01, Volume: 301 ( Pt 1)

    Topics: Animals; Anisomycin; Cell Line; Cycloheximide; Dactinomycin; Ethers, Cyclic; HeLa Cells; Humans; Okadaic Acid; Phosphorylation; Protein Synthesis Inhibitors; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1994
Effect of tumour promoting agents on protein phosphorylation in human placenta.
    The International journal of biochemistry, 1994, Volume: 26, Issue:7

    Topics: Autoradiography; Blotting, Western; Carcinogens; Ethers, Cyclic; Female; Humans; Molecular Weight; Okadaic Acid; Phosphorylation; Placenta; Pregnancy; Pregnancy Proteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Tissue Preservation

1994
Modulation of nucleocytosolic [Ca2+] gradient in smooth muscle by protein phosphorylation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1994, Volume: 8, Issue:11

    Topics: Adenosine Triphosphate; Animals; Benzoquinones; Calcium; Cell Line; Cell Nucleus; Colforsin; Cricetinae; Cytosol; Diacylglycerol Kinase; Epidermal Growth Factor; Ethers, Cyclic; Homeostasis; Kinetics; Lactams, Macrocyclic; Leiomyosarcoma; Marine Toxins; Mesocricetus; Models, Biological; Muscle, Smooth; Okadaic Acid; Oxazoles; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Quinazolines; Quinazolinones; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1994
Functional characterization of the Na(+)-H+ exchanger in rat mast cells: crosstalks between different kinase pathways.
    European journal of pharmacology, 1994, May-17, Volume: 267, Issue:3

    Topics: Animals; Cholera Toxin; Ethers, Cyclic; Hydrogen-Ion Concentration; Mast Cells; Okadaic Acid; Pertussis Toxin; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium; Sodium Fluoride; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1994
Neurotoxic effect of okadaic acid, a seafood-related toxin, on cultured cerebellar neurons.
    Annals of the New York Academy of Sciences, 1993, May-28, Volume: 679

    Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Colforsin; Ethers, Cyclic; Glutamates; Glutamic Acid; Kainic Acid; Marine Toxins; Models, Neurological; Neurons; Neurotoxins; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Shellfish; Tetradecanoylphorbol Acetate

1993
Phenylarsine oxide and phorbol myristate acetate inhibit the CD3-induced rise of cytosolic Ca2+ in Jurkat cells by refilling internal Ca2+ stores.
    The Biochemical journal, 1994, Feb-01, Volume: 297 ( Pt 3)

    Topics: Arsenicals; Biological Transport; Calcium; CD3 Complex; Cell Line; Cytosol; Ethers, Cyclic; Humans; Ionomycin; Okadaic Acid; Phosphatidylserines; Phosphorylation; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine

1994
Transactivation of human hepatitis B virus X protein, HBx, operates through a mechanism distinct from protein kinase C and okadaic acid activation pathways.
    Virology, 1994, Feb-15, Volume: 199, Issue:1

    Topics: Base Sequence; Cell Line; DNA, Viral; Ethers, Cyclic; Hepatitis B virus; Humans; Molecular Sequence Data; Okadaic Acid; Protein Kinase C; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Activation; Viral Regulatory and Accessory Proteins

1994
Modulation of the Na-H antiport by insulin: interplay between protein kinase C, tyrosine kinase, and protein phosphatases.
    Journal of cellular physiology, 1994, Volume: 159, Issue:2

    Topics: Alkaloids; Animals; Ethers, Cyclic; Insulin; Male; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate

1994
Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, May-10, Volume: 91, Issue:10

    Topics: Animals; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ethers, Cyclic; Evoked Potentials; Exocytosis; Islets of Langerhans; Membrane Potentials; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate

1994
Cytosolic protein phosphatase may turn off activated NADPH oxidase in guinea pig neutrophils.
    Archives of biochemistry and biophysics, 1993, Volume: 306, Issue:1

    Topics: Animals; Cytosol; Enzyme Activation; Ethers, Cyclic; Female; Guinea Pigs; Kinetics; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Superoxides; Tetradecanoylphorbol Acetate

1993
Differential regulation of human B-lymphocyte tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin (TNF-beta) production by protein phosphatase 1 and 2A inhibitor.
    Blood, 1993, Nov-01, Volume: 82, Issue:9

    Topics: B-Lymphocytes; Cell Line; Ethers, Cyclic; Humans; Lymphotoxin-alpha; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha

1993
Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages.
    The Journal of biological chemistry, 1993, Nov-15, Volume: 268, Issue:32

    Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Macrophages; Mice; Molecular Sequence Data; Okadaic Acid; Peptide Mapping; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan

1993
Phenylarsine oxide and hydrogen peroxide stimulate glucose transport via different pathways in isolated cardiac myocytes.
    Biochimica et biophysica acta, 1993, Nov-21, Volume: 1153, Issue:1

    Topics: 3-O-Methylglucose; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arsenicals; Biological Transport; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Ethers, Cyclic; Ethylmaleimide; Glucose; Heart; Hydrogen Peroxide; Insulin; Methylglucosides; Myocardium; Okadaic Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vanadates

1993
Phosphatase inhibitors, gap junctional intercellular communication and [125I]-EGF binding in hamster fibroblasts.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: Aluminum Compounds; Animals; Cell Communication; Cell Line; Connexin 43; Cricetinae; Cricetulus; Embryo, Mammalian; Epidermal Growth Factor; Ethers, Cyclic; Fibroblasts; Fluorides; Intercellular Junctions; Iodine Radioisotopes; Kinetics; Lung; Marine Toxins; Mesocricetus; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate; Vanadates; Vanadium Compounds

1993
Okadaic acid, a phosphatase inhibitor, enhances the phorbol ester-induced interleukin-1 beta expression via an AP-1-mediated mechanism.
    Scandinavian journal of immunology, 1993, Volume: 38, Issue:6

    Topics: Cell Line; Electrophoresis, Agar Gel; Ethers, Cyclic; Gene Expression Regulation; Humans; Interleukin-1; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1993
Modulators of cellular protein phosphorylation alter the trans-activation function of human progesterone receptor and the biological activity of progesterone antagonists.
    Breast cancer research and treatment, 1993, Volume: 27, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetyl Coenzyme A; Breast Neoplasms; Cell Line; DNA-Binding Proteins; Drug Synergism; Ethers, Cyclic; Female; Humans; Kinetics; Mifepristone; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Receptors, Progesterone; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1993
The role of cytosolic Ca2+, protein kinase C, and protein kinase A in hormonal stimulation of phospholipase D in rat hepatocytes.
    The Journal of biological chemistry, 1994, Jan-14, Volume: 269, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ethers, Cyclic; Glycerophospholipids; Isoquinolines; Liver; Male; Okadaic Acid; Phosphatidic Acids; Phospholipase D; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins

1994
Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells.
    The Journal of biological chemistry, 1994, Jan-14, Volume: 269, Issue:2

    Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Ethers, Cyclic; Gene Expression; Genes, jun; Humans; In Vitro Techniques; Leukemia, Myeloid; Molecular Sequence Data; Monocytes; Okadaic Acid; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1994
Carboxyl methylation of protein phosphatase 2A from Xenopus eggs is stimulated by cAMP and inhibited by okadaic acid.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: Animals; Calcium; Calmodulin; Caseins; Cattle; Cyclic AMP; Cytosol; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Female; Kinetics; Methylation; Okadaic Acid; Ovum; Phosphoprotein Phosphatases; Protein Phosphatase 2; S-Adenosylmethionine; Second Messenger Systems; Substrate Specificity; Tetradecanoylphorbol Acetate; Xenopus laevis

1994
Phorbol esters and norepinephrine destabilize alpha 1B-adrenergic receptor mRNA in vascular smooth muscle cells.
    The Journal of biological chemistry, 1994, Jan-21, Volume: 269, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Bradykinin; Cells, Cultured; Diglycerides; Down-Regulation; Ethers, Cyclic; Inositol Phosphates; Isoquinolines; Kinetics; Models, Biological; Muscle, Smooth, Vascular; Norepinephrine; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Rabbits; Receptors, Adrenergic, alpha-1; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Modulation of superoxide generation in in vivo lipopolysaccharide-primed Kupffer cells by staurosporine, okadaic acid, manoalide, arachidonic acid, genistein and sodium orthovanadate.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: Alkaloids; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Enzyme Inhibitors; Ethers, Cyclic; Genistein; In Vitro Techniques; Isoflavones; Kupffer Cells; Lipopolysaccharides; Male; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Vanadates

1994
Differential regulation of human progesterone receptor A and B form-mediated trans-activation by phosphorylation.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Base Sequence; Blotting, Western; Cell Line; Drug Synergism; Ethers, Cyclic; Gene Expression; Humans; Mifepristone; Molecular Sequence Data; Okadaic Acid; Phosphoproteins; Phosphorylation; Promegestone; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection

1993
Insulin and okadaic acid induce Rab4 redistribution in adipocytes.
    The Journal of biological chemistry, 1993, Sep-15, Volume: 268, Issue:26

    Topics: Adipose Tissue; Animals; Biological Transport; Brain; Cell Fractionation; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cytosol; Deoxyglucose; Dose-Response Relationship, Drug; Epididymis; Ethers, Cyclic; GTP-Binding Proteins; Insulin; Male; Models, Biological; Monosaccharide Transport Proteins; Okadaic Acid; rab4 GTP-Binding Proteins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1993
Insulin-mimetic actions of phorbol ester in cultured adult rat hepatocytes. Lack of phorbol-ester-elicited inhibition of the insulin signal.
    The Biochemical journal, 1993, Jan-15, Volume: 289 ( Pt 2)

    Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cells, Cultured; Enzyme Activation; Enzyme Induction; Ethers, Cyclic; Fructosediphosphates; Glucagon; Glycolysis; Insulin; Kinetics; Liver; Liver Glycogen; Male; Okadaic Acid; Ornithine Decarboxylase; Phosphoenolpyruvate Carboxykinase (GTP); Phosphofructokinase-2; Phosphoprotein Phosphatases; Phosphotransferases; Protein Kinase C; Pyruvate Kinase; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors

1993
Growth arrest of the breast cancer cell line, T47D, by TNF alpha; cell cycle specificity and signal transduction.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Division; DNA, Neoplasm; Ethers, Cyclic; Humans; Isoquinolines; Okadaic Acid; Piperazines; Protein Kinase C; Sensitivity and Specificity; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Neutrophils stimulated with a chemotactic peptide or a phorbol ester exhibit different alterations in the activities of a battery of protein kinases.
    The Journal of biological chemistry, 1993, Mar-05, Volume: 268, Issue:7

    Topics: Animals; Ethers, Cyclic; Guinea Pigs; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate

1993
Monoclonal antibody 8A2-induced retraction appears to be mediated by protein phosphorylation in goldfish retinal ganglion cell axons.
    Developmental biology, 1993, Volume: 156, Issue:1

    Topics: Alkaloids; Animals; Antibodies, Monoclonal; Axons; Calcium; Cyclic AMP; Ethers, Cyclic; Goldfish; Nerve Regeneration; Okadaic Acid; Organ Culture Techniques; Phorbol Esters; Phorbols; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Retinal Ganglion Cells; Staurosporine; Tetradecanoylphorbol Acetate

1993
Okadaic acid induces down-modulation and shedding of tumor necrosis factor receptors. Comparison with another tumor promoter, phorbol ester.
    The Journal of biological chemistry, 1993, Mar-15, Volume: 268, Issue:8

    Topics: Down-Regulation; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1993
Vasodilatory effects of okadaic acid on the canine cerebral artery.
    Brain research bulletin, 1993, Volume: 30, Issue:5-6

    Topics: Angiography; Animals; Basilar Artery; Cerebral Arteries; Dinoprost; Dogs; Ethers, Cyclic; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Okadaic Acid; Phosphoric Monoester Hydrolases; Potassium; Tetradecanoylphorbol Acetate; Vasodilation; Vasodilator Agents

1993
Phosphorylation and activation of the arachidonate-mobilizing phospholipase A2 in macrophages in response to bacteria.
    European journal of biochemistry, 1993, Apr-01, Volume: 213, Issue:1

    Topics: Animals; Arachidonic Acids; Bacterial Physiological Phenomena; Cells, Cultured; Dinoprostone; Enzyme Activation; Ethers, Cyclic; Female; Gardnerella vaginalis; Macrophages; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan

1993
Regulation of neutrophil respiratory burst by protein phosphatases.
    Life sciences, 1993, Volume: 52, Issue:21

    Topics: Ethers, Cyclic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate

1993
Phorbol ester, prostaglandin E2, forskolin and okadaic acid differentially modulate interleukin-4-versus interleukin-2-dependent immunoglobulin induction in human cellular models, in contrast to other selected modifiers of cellular activation.
    International archives of allergy and immunology, 1993, Volume: 101, Issue:2

    Topics: Antibodies, Monoclonal; B-Lymphocytes; Cells, Cultured; Colforsin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Interleukin-2; Interleukin-4; Interleukins; Lymphocyte Activation; Okadaic Acid; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1993
Contrasting effects of two tumour promoters, phorbol myristate acetate and okadaic acid, on T-cell responses and activation of p42 MAP-kinase/ERK-2.
    Immunology, 1993, Volume: 79, Issue:1

    Topics: Cells, Cultured; Ethers, Cyclic; Humans; Immunoblotting; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Interleukin-2; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate

1993
Defective translocation of protein kinase C in multidrug-resistant HL-60 cells confers a reversible loss of phorbol ester-induced monocytic differentiation.
    The Journal of biological chemistry, 1993, Jun-15, Volume: 268, Issue:17

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Differentiation; Cell Nucleus; Drug Resistance; Ethers, Cyclic; Gene Expression; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Monocytes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine

1993
Interleukin-8 production by the human cervix.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:3

    Topics: Abortifacient Agents, Nonsteroidal; Alprostadil; Analysis of Variance; Cervix Uteri; Culture Techniques; Dimethylformamide; Dinoprostone; Ethers, Cyclic; Female; Humans; Interleukin-8; Lipopolysaccharides; Menopause; Okadaic Acid; Phosphoprotein Phosphatases; Pregnancy; Progesterone; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1993
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
    Molecular and cellular biology, 1993, Volume: 13, Issue:10

    Topics: 3T3 Cells; Animals; Base Sequence; Cell Transformation, Neoplastic; Cloning, Molecular; DNA; Enzyme Activation; Estradiol; Ethers, Cyclic; Humans; Kinetics; Mice; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptors, Estrogen; Retroviridae; Signal Transduction; Tetradecanoylphorbol Acetate

1993
Absence of synergistic effects on tumor promotion in CD-1 mouse skin by simultaneous applications of two different types of tumor promoters, okadaic acid and teleocidin.
    Cancer research, 1993, Mar-01, Volume: 53, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Synergism; Enzyme Induction; Ethers, Cyclic; Female; Lyngbya Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Phosphorylation; Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate

1993
Okadaic acid activates p42 mitogen-activated protein kinase (MAP kinase; ERK-2) in B-lymphocytes but inhibits rather than augments cellular proliferation: contrast with phorbol 12-myristate 13-acetate.
    The Biochemical journal, 1993, Mar-01, Volume: 290 ( Pt 2)

    Topics: B-Lymphocytes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Chromatography, Gel; Enzyme Activation; Ethers, Cyclic; Humans; Immunoglobulin M; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1993
Rapid phosphorylation of 28-kDa heat-shock protein by treatment with okadaic acid and phorbol ester of BALB/MK-2 mouse keratinocytes.
    European journal of biochemistry, 1993, May-01, Volume: 213, Issue:3

    Topics: Animals; Carcinogens; Cell Line; Ethers, Cyclic; Heat-Shock Proteins; Humans; Keratinocytes; Mice; Okadaic Acid; Peptide Mapping; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1993
Phorbol ester-dependent regulation of nuclear protein tyrosine phosphatase in situ.
    Cellular signalling, 1995, Volume: 7, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Nucleus; Enzyme Inhibitors; Ethers, Cyclic; Immunoblotting; Isoquinolines; Lymphocytes; Molecular Weight; Nuclear Proteins; Okadaic Acid; Phosphorylation; Piperazines; Protein Kinase C; Protein Tyrosine Phosphatases; Spleen; Swine; Tetradecanoylphorbol Acetate; Time Factors

1995
Thyroid hormones stabilize acetylcholinesterase mRNA in neuro-2A cells that overexpress the beta 1 thyroid receptor.
    The Journal of biological chemistry, 1995, Dec-22, Volume: 270, Issue:51

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholinesterase; Animals; Cell Line; Dichlororibofuranosylbenzimidazole; Enzyme Inhibitors; Ethers, Cyclic; Humans; Isoquinolines; Kinetics; Mice; Naphthalenes; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Thyroid Hormone; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Triiodothyronine; Tumor Cells, Cultured

1995
Insulin and vasopressin elicit inhibition of cholera-toxin-stimulated adenylate cyclase activity in both hepatocytes and the P9 immortalized hepatocyte cell line through an action involving protein kinase C.
    The Biochemical journal, 1995, Dec-15, Volume: 312 ( Pt 3)

    Topics: 3T3 Cells; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaline Phosphatase; Animals; Cell Line, Transformed; CHO Cells; Cholera Toxin; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Insulin; Kinetics; Liver; Male; Mice; Okadaic Acid; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasopressins

1995
Ability of okadaic acid and other protein phosphatase inhibitors to mimic the stimulatory effects of 12-O-tetradecanoylphorbol-13-acetate on hydroperoxide production in mouse epidermis in vivo.
    Cancer letters, 1996, Jan-02, Volume: 98, Issue:2

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethers, Cyclic; Female; Hydrogen Peroxide; Marine Toxins; Mice; Mice, Inbred Strains; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Skin; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1996
Okadaic acid gives concentration-dependent reciprocal effects on the fluid phase endocytosis activated by Ca2+ and phorbol 12-myristate 13-acetate.
    Journal of cellular physiology, 1996, Volume: 166, Issue:1

    Topics: Biological Transport; Calcium; Dose-Response Relationship, Drug; Endocytosis; Endosomes; Enzyme Inhibitors; Ethers, Cyclic; Fibrosarcoma; Humans; Okadaic Acid; Phosphorylation; Protein Kinase Inhibitors; Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histone H3/HMG-14 phosphorylation or c-fos and c-jun induction.
    Journal of cell science, 1995, Volume: 108 ( Pt 11)

    Topics: 3T3 Cells; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Chromatin; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Ethers, Cyclic; ets-Domain Protein Elk-1; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; High Mobility Group Proteins; Histones; Isoenzymes; MAP Kinase Kinase 4; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase Kinases; Okadaic Acid; Phosphorylation; Protein Binding; Protein Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate; Transcription Factors; Ultraviolet Rays

1995
Protein kinase C regulates cytokine-induced tissue factor transcription and procoagulant activity in human endothelial cells.
    The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:1

    Topics: Blood Coagulation; Calcimycin; Cell Adhesion; Cytokines; Endothelium, Vascular; Epoprostenol; Ethers, Cyclic; Humans; Interleukin-1; Naphthalenes; Neutrophils; Okadaic Acid; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription, Genetic; Tumor Necrosis Factor-alpha

1996
Effect of diverse tumor promoters on the expression of gap-junctional proteins connexin (Cx)26, Cx31.1, and Cx43 in SENCAR mouse epidermis.
    Molecular carcinogenesis, 1996, Volume: 15, Issue:3

    Topics: Animals; Anthracenes; Benzoyl Peroxide; Carcinogens; Cell Communication; Connexins; Ethers, Cyclic; Female; Gap Junctions; Mice; Mice, Inbred SENCAR; Okadaic Acid; Skin; Tetradecanoylphorbol Acetate

1996
Erythropoietin stimulates phosphorylation of eIF-4E and identification of a 37-kD phosphoprotein that binds mRNA caps in erythroblasts.
    Experimental hematology, 1996, Volume: 24, Issue:3

    Topics: Anemia; Animals; Erythroblasts; Erythropoietin; Ethers, Cyclic; Eukaryotic Initiation Factor-4E; Female; Friend murine leukemia virus; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Molecular Weight; Okadaic Acid; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; RNA Caps; RNA, Messenger; Spleen; Tetradecanoylphorbol Acetate

1996
Protein kinase C inhibitors enhance G-protein induced phospholipase A2 activation in intact human platelets.
    FEBS letters, 1996, Mar-04, Volume: 381, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aluminum Compounds; Arachidonic Acid; beta-Thromboglobulin; Blood Platelets; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Fluorides; GTP-Binding Proteins; Humans; Isoquinolines; Kinetics; Naphthalenes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Piperazines; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin

1996
d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26

    Topics: Amino Acid Sequence; Animals; Antioxidants; Aorta; Cell Cycle; Cell Division; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethers, Cyclic; Flow Cytometry; Isomerism; Kinetics; Marine Toxins; Molecular Sequence Data; Muscle, Smooth, Vascular; Naphthalenes; Okadaic Acid; Oligopeptides; Oxazoles; Protein Kinase C; Rats; Substrate Specificity; Tetradecanoylphorbol Acetate; Thymidine; Vitamin E

1995
Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Alkaline Phosphatase; Bucladesine; Clone Cells; Colforsin; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; Female; Humans; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Marine Toxins; NFATC Transcription Factors; Nuclear Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Protein Phosphatase 1; Recombinant Proteins; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured

1996
Regulation of p21WAF1/CIP1 expression by p53-independent pathways.
    Oncogene, 1996, Apr-04, Volume: 12, Issue:7

    Topics: Alkaloids; Blood; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Ethers, Cyclic; Gene Expression Regulation; Genes, p53; Humans; Okadaic Acid; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.
    The Journal of biological chemistry, 1996, Mar-15, Volume: 271, Issue:11

    Topics: Amino Acid Sequence; Antioxidants; Cell Line; Ethers, Cyclic; Humans; Ionomycin; Molecular Sequence Data; NF-kappa B; NF-kappa B p50 Subunit; Okadaic Acid; Oxidation-Reduction; Phosphorylation; Protein Precursors; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation

1996
Role of protein phosphatase 2A in the regulation of mitogen-activated protein kinase activity in ventricular cardiomyocytes.
    Biochemical and biophysical research communications, 1996, Apr-25, Volume: 221, Issue:3

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Heart Ventricles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 2; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1996
Age-related reductions in the activation of mitogen-activated protein kinases p44mapk/ERK1 and p42mapk/ERK2 in human T cells stimulated via ligation of the T cell receptor complex.
    Cellular immunology, 1996, Mar-15, Volume: 168, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Ethers, Cyclic; Female; Humans; Ionomycin; Ionophores; Isoenzymes; Lectins; Lymphocyte Activation; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muromonab-CD3; Okadaic Acid; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate

1996
Okadaic acid, sphingosine, and phorbol ester reversibly modulate heat induction on protein kinase FA/GSK-3 alpha in A431 cells.
    Journal of cellular biochemistry, 1996, Volume: 60, Issue:2

    Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Enzyme Induction; Enzyme Inhibitors; Ethers, Cyclic; Glycogen Synthase Kinase 3; Hot Temperature; Humans; Molecular Sequence Data; Okadaic Acid; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Involvement of protein phosphatase 2A in PKC-independent pathway of neutrophil superoxide generation by fMLP.
    Journal of cellular biochemistry, 1996, Volume: 60, Issue:2

    Topics: Calcium; Enzyme Inhibitors; Ethers, Cyclic; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Phosphatase 2; Superoxides; Tetradecanoylphorbol Acetate

1996
Okadaic acid inhibits the signal responsible for activation of the NADPH-oxidase in neutrophils stimulated with serum-opsonized yeast.
    Journal of leukocyte biology, 1996, Volume: 59, Issue:5

    Topics: Animals; Cell Fusion; Enzyme Inhibitors; Ethers, Cyclic; Humans; Hydrogen Peroxide; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Okadaic Acid; Phagocytosis; Phosphoprotein Phosphatases; Rabbits; Reactive Oxygen Species; Respiratory Burst; Saccharomyces cerevisiae; Tetradecanoylphorbol Acetate

1996
Atrial natriuretic peptide inhibits mitogen-activated protein kinase through the clearance receptor. Potential role in the inhibition of astrocyte proliferation.
    The Journal of biological chemistry, 1996, Jun-14, Volume: 271, Issue:24

    Topics: Animals; Astrocytes; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Diencephalon; Endothelins; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Fetus; Kinetics; Okadaic Acid; Phosphorylation; Platelet-Derived Growth Factor; Rats; Receptors, Atrial Natriuretic Factor; Tetradecanoylphorbol Acetate; Vanadates

1996
Mitoxantrone induces nonimmunological histamine release from rat mast cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Antineoplastic Agents; Calcium; Carcinogens; Cell Division; Cyclic AMP; Drug Interactions; Enzyme Inhibitors; Ethers, Cyclic; Exocytosis; Histamine Release; Mast Cells; Mitoxantrone; Okadaic Acid; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Phosphodiesterase Inhibitors; Pleura; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Theophylline; Trifluoperazine

1996
Modulation of the stress-induced synthesis of stress proteins by a phorbol ester and okadaic acid.
    Journal of biochemistry, 1995, Volume: 118, Issue:3

    Topics: Alkaloids; Animals; Arachidonic Acid; Arsenites; Blotting, Northern; Blotting, Western; Enzyme Activation; Ethers, Cyclic; Glioma; Heat-Shock Proteins; Okadaic Acid; Protein Kinase C; Rats; RNA, Messenger; Serine Proteinase Inhibitors; Staurosporine; Stimulation, Chemical; Stress, Physiological; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Inducer-specific bidirectional regulation by thalidomide and phenylphthalimides of tumor necrosis factor-alpha production.
    Biochemical and biophysical research communications, 1996, Jul-16, Volume: 224, Issue:2

    Topics: Carcinogens; Dose-Response Relationship, Drug; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lyngbya Toxins; Molecular Structure; Okadaic Acid; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Thalidomide; Thapsigargin; Tumor Necrosis Factor-alpha

1996
GH inhibition of lipogenesis and stimulation of lipolysis in sheep adipose tissue: involvement of protein serine phosphorylation and dephosphorylation and phospholipase C.
    The Journal of endocrinology, 1996, Volume: 150, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetyl-CoA Carboxylase; Adipose Tissue; Alkaloids; Animals; Bridged-Ring Compounds; Culture Techniques; Ethers, Cyclic; Glycerol; Growth Hormone; Isoquinolines; Lipid Metabolism; Lipids; Lipolysis; Male; Norbornanes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Sheep; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones; Type C Phospholipases

1996
Phosphorylation/dephosphorylation steps are key events in the phytochrome-mediated enhancement of nitrate reductase mRNA levels and enzyme activity in maize.
    Molecular & general genetics : MGG, 1996, Jul-19, Volume: 251, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Darkness; Enzyme Inhibitors; Ethers, Cyclic; Gene Expression Regulation, Plant; Isoquinolines; Light; Nitrate Reductase; Nitrate Reductases; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Phytochrome; Piperazines; Protein Kinase C; RNA, Messenger; RNA, Plant; Signal Transduction; Tetradecanoylphorbol Acetate; Zea mays

1996
Modulation of macrophage scavenger receptor transport by protein phosphorylation.
    Journal of lipid research, 1996, Volume: 37, Issue:3

    Topics: Animals; Blotting, Northern; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pinocytosis; Protein Binding; Protein Kinase C; Receptors, Immunologic; Receptors, Scavenger; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate

1996
Phorbol ester and okadaic acid regulation of Na-2Cl-K cotransport in rabbit tracheal epithelial cells.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 1

    Topics: Animals; Bumetanide; Carrier Proteins; Cells, Cultured; Electric Conductivity; Epithelial Cells; Epithelium; Male; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Rabbits; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Time Factors; Trachea

1996
Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester.
    Journal of neurochemistry, 1996, Volume: 67, Issue:2

    Topics: Adenylyl Cyclases; Amiloride; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Calcimycin; Carrier Proteins; Colforsin; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycine; Kinetics; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Proliferation-dependent changes in arachidonic acid mobilization from phospholipids of 3T6 fibroblasts.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 432, Issue:4

    Topics: Animals; Arachidonic Acid; Bradykinin; Calcimycin; Cell Division; Cell Line; Culture Media; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phospholipids; Phosphoric Monoester Hydrolases; Tetradecanoylphorbol Acetate

1996
Control of SHB gene expression by protein phosphorylation.
    Cellular signalling, 1996, Volume: 8, Issue:1

    Topics: 3T3 Cells; Animals; Becaplermin; Enzyme Inhibitors; Ethers, Cyclic; Gene Expression Regulation; Genistein; Isoflavones; Mice; Nitriles; Okadaic Acid; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrphostins

1996
Effects of protein kinase C and phosphoprotein phosphatase modulators on Ehrlich cell plasma membrane redox system activity.
    Biochimica et biophysica acta, 1996, Aug-28, Volume: 1313, Issue:2

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cyclosporine; Enzyme Inhibitors; Ethers, Cyclic; NADH, NADPH Oxidoreductases; Okadaic Acid; Oxidation-Reduction; Phosphoprotein Phosphatases; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Okadaic acid-induced transcriptional downregulation of type I collagen gene expression is mediated by protein phosphatase 2A.
    Molecular and cellular biochemistry, 1996, May-10, Volume: 158, Issue:1

    Topics: 3T3 Cells; Animals; Chloramphenicol O-Acetyltransferase; Collagen; Down-Regulation; Gene Expression Regulation; Genes, Reporter; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Procollagen; Promoter Regions, Genetic; Protein Phosphatase 2; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

1996
Dephosphorylation of a 34kd triton-insoluble F-actin pool protein is associated with phorbol ester-induced actin polymerization in human polymorphonuclear leukocytes.
    Hematopathology and molecular hematology, 1996, Volume: 10, Issue:1-2

    Topics: Actins; Biopolymers; Detergents; Enzyme Inhibitors; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Octoxynol; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Solubility; Tetradecanoylphorbol Acetate

1996
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17

    Topics: Base Sequence; Caffeic Acids; Cell Line; Ceramides; DNA-Binding Proteins; Histiocytes; Humans; I-kappa B Proteins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phenylethyl Alcohol; Phosphorylation; Protein Binding; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1996
Negative regulatory activity of a prostaglandin F2 alpha receptor associated protein (FPRP).
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:4

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cloning, Molecular; COS Cells; Dinoprost; DNA, Complementary; Endoplasmic Reticulum; Golgi Apparatus; Immunohistochemistry; Mice; Molecular Sequence Data; Neoplasm Proteins; Okadaic Acid; Proteins; Rats; Receptors, Prostaglandin; Tetradecanoylphorbol Acetate; Transfection

1996
Dephosphorylation of cofilin in polymorphonuclear leukocytes derived from peripheral blood.
    Experimental cell research, 1996, Aug-25, Volume: 227, Issue:1

    Topics: Actin Depolymerizing Factors; Androstadienes; Animals; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethers, Cyclic; Humans; Ionophores; Marine Toxins; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Swine; Tetradecanoylphorbol Acetate; Wortmannin

1996
Activation of protein kinase C down-regulates glial but not neuronal taurine uptake.
    Neuroscience letters, 1996, Mar-08, Volume: 206, Issue:1

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Ethers, Cyclic; Neuroglia; Neurons; Okadaic Acid; Protein Kinase C; Rats; Rats, Wistar; Taurine; Tetradecanoylphorbol Acetate

1996
Ca2+/calmodulin and cyclic 3,5' adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic beta-cell.
    Endocrinology, 1996, Volume: 137, Issue:11

    Topics: Acetylcholine; Animals; Calcium; Calmodulin; Cell Line; Chelating Agents; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Egtazic Acid; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Potassium; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Tolbutamide

1996
Evidence for a phorbol ester-insensitive phosphorylation step in capacitative calcium entry in rat thymic lymphocytes.
    The Journal of biological chemistry, 1996, Oct-25, Volume: 271, Issue:43

    Topics: Animals; Biological Transport; Calcium; Enzyme Inhibitors; Ion Transport; Lymphocytes; Male; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thapsigargin; Thymus Gland

1996
Inducer-specific regulators of tumor necrosis factor alpha production.
    Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:10

    Topics: Carcinogens; Drug Synergism; HL-60 Cells; Humans; Okadaic Acid; Phthalimides; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1996
Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.
    Molecular pharmacology, 1996, Volume: 50, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Amino Acid Sequence; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Molecular Sequence Data; Naphthalenes; Nitriles; Nitrophenols; Nuclear Envelope; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrphostins

1996
Regulation of natural killer cell-mediated cytotoxicity by serine/threonine phosphatases: identification of a calyculin A-sensitive serine/threonine kinase.
    The Biochemical journal, 1996, Nov-15, Volume: 320 ( Pt 1)

    Topics: CD28 Antigens; Cell Line; Cytotoxicity, Immunologic; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Enzyme Stability; Ionophores; Killer Cells, Natural; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Serine-Threonine Kinases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine

1996
Theileria parva sporozoite entry into bovine lymphocytes involves both parasite and host cell signal transduction processes.
    Experimental parasitology, 1996, Volume: 84, Issue:3

    Topics: Adenosine; Animals; Cattle; Down-Regulation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Isoflavones; Lymphocytes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Suramin; Tetradecanoylphorbol Acetate; Theileria parva; Trypanocidal Agents; Type C Phospholipases

1996
12-O-Tetradecanoylphorbol-13-acetate-induced dephosphorylation of protein kinase Calpha correlates with the presence of a membrane-associated protein phosphatase 2A heterotrimer.
    The Journal of biological chemistry, 1996, Dec-20, Volume: 271, Issue:51

    Topics: Animals; Cell Membrane; COS Cells; Down-Regulation; Enzyme Activation; Isoenzymes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinase C-alpha; Protein Phosphatase 2; Tetradecanoylphorbol Acetate

1996
Okadaic acid as a probe for regulation in vitro of Mg(2+), Ca(2+)-ATPase activity in rat cortical and cerebellar synaptosomal membranes.
    Cellular signalling, 1996, Volume: 8, Issue:6

    Topics: Animals; Ca(2+) Mg(2+)-ATPase; Calmodulin; Cerebellum; Cerebral Cortex; Cyclic AMP; Enzyme Inhibitors; Intracellular Membranes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate

1996
Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus major immediate-early promoters in monocyte and T-lympho
    Journal of virology, 1996, Volume: 70, Issue:12

    Topics: 3T3 Cells; Animals; Antigens, Viral; Binding Sites; Cell Extracts; Cell Line; Cell Nucleus; Cytomegalovirus; DNA-Binding Proteins; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Enhancer Elements, Genetic; ets-Domain Protein Elk-1; HeLa Cells; HL-60 Cells; Humans; Immediate-Early Proteins; Jurkat Cells; Mice; Monocytes; Mutagenesis; NF-kappa B; Nuclear Proteins; Okadaic Acid; Primates; Promoter Regions, Genetic; Proto-Oncogene Protein c-ets-2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogene Proteins c-fos; Repressor Proteins; Serum Response Factor; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Transfection; Tumor Cells, Cultured

1996
Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration. An immunofluorescence microscopy analysis.
    Circulation research, 1997, Volume: 80, Issue:1

    Topics: Animals; Cells, Cultured; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Microscopy, Fluorescence; Myocardial Contraction; Myocardium; Myofibrils; Okadaic Acid; Phosphorylation; Phosphotransferases; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1997
Regulation of rat interstitial collagenase gene expression in growth cartilage and chondrocytes by vitamin D3, interleukin-1 beta, and okadaic acid.
    Journal of cellular biochemistry, 1996, Dec-15, Volume: 63, Issue:4

    Topics: Actins; Animals; Blotting, Northern; Carcinogens; Cartilage; Cells, Cultured; Cholecalciferol; Collagenases; Dactinomycin; DNA, Complementary; Electrophoresis, Agar Gel; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genes, Reporter; Interleukin-1; Male; Nucleic Acid Synthesis Inhibitors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

1996
Okadaic acid induces hyperphosphorylation of tau independently of mitogen-activated protein kinase activation.
    Journal of neurochemistry, 1997, Volume: 68, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Neuroglia; Neurons; Okadaic Acid; Phosphorylation; Rats; tau Proteins; Tetradecanoylphorbol Acetate

1997
Evidence for different mechanisms of growth inhibition of T-cell lymphoma by phorbol esters and concanavalin A.
    The Journal of biological chemistry, 1997, Jan-24, Volume: 272, Issue:4

    Topics: Animals; Concanavalin A; Cyclin-Dependent Kinases; G1 Phase; G2 Phase; Humans; Lymphoma, T-Cell; Mice; Mitosis; Okadaic Acid; Phorbol Esters; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Effect of the protein phosphatase inhibitor okadaic acid on FSH-induced granulosa cell steroidogenesis.
    The Journal of endocrinology, 1997, Volume: 152, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Okadaic Acid; Phosphoprotein Phosphatases; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

1997
Induction of prostaglandin H synthase-2 and tumor necrosis factor-alpha in human amnionic WISH cells by various stimuli occurs through distinct intracellular mechanisms.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Amnion; Base Sequence; Blotting, Northern; Cell Line; Cyclooxygenase 2; Dinoprostone; DNA Primers; Enzyme Induction; Female; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Kinetics; Membrane Proteins; Models, Biological; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; Pregnancy; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha

1997
Regulatory mechanisms involved in activator-protein-1 (AP-1)-mediated activation of glutathione-S-transferase gene expression by chemical agents.
    European journal of biochemistry, 1997, Jan-15, Volume: 243, Issue:1-2

    Topics: Benzoflavones; Cell Nucleus; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Humans; Hydroquinones; Methylcholanthrene; Okadaic Acid; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation

1997
Modulation of levels of a negative transcription factor for IL-2 by 12-O-tetradecanoyl phorbol-13-acetate and okadaic acid.
    Cytokine, 1996, Volume: 8, Issue:11

    Topics: Animals; Cattle; Cells, Cultured; Concanavalin A; DNA; Interleukin-2; Lymphocyte Activation; Lymphocytes; Okadaic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors

1996
Regulation of the functional activity of the human dopamine transporter by protein kinase C.
    Biochemical pharmacology, 1997, Mar-07, Volume: 53, Issue:5

    Topics: Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
Dynactin phosphorylation is modulated in response to cellular effectors.
    Biochemical and biophysical research communications, 1997, Mar-27, Volume: 232, Issue:3

    Topics: Animals; Biological Transport, Active; Cell Line; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Dynactin Complex; Dyneins; Enzyme Activation; Microtubule-Associated Proteins; Microtubules; Models, Biological; Okadaic Acid; Organelles; Phosphorylation; Protein Conformation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

1997
Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus.
    Virus research, 1997, Volume: 48, Issue:2

    Topics: Calcimycin; Cells, Cultured; Colforsin; Cytomegalovirus; Endothelium, Vascular; Enzyme Activation; Humans; Iloprost; Okadaic Acid; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Umbilical Veins

1997
Sealing effects of (-)-epigallocatechin gallate on protein kinase C and protein phosphatase 2A.
    Biophysical chemistry, 1997, Apr-22, Volume: 65, Issue:2-3

    Topics: Catechin; Circular Dichroism; Enzyme Inhibitors; Lipid Bilayers; Liposomes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 2; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

1997
Parathyroid hormone-related protein and human myometrial cells: action and regulation.
    Molecular and cellular endocrinology, 1997, Apr-25, Volume: 129, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Chorionic Gonadotropin; Colforsin; Corticotropin-Releasing Hormone; Female; Gene Expression Regulation; Humans; Muscle Relaxation; Myometrium; Okadaic Acid; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Pregnancy; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate

1997
Differential regulation of interstitial collagenase (MMP-1) gene expression by ETS transcription factors.
    Oncogene, 1997, Jun-05, Volume: 14, Issue:22

    Topics: 3T3 Cells; Animals; Collagenases; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 1; Mice; Okadaic Acid; Promoter Regions, Genetic; Protein Binding; Tetradecanoylphorbol Acetate; Transcription Factors

1997
Cell stresses regulate the phosphorylation state of c-Jun and ATF2 in ventricular myocytes.
    Biochemical Society transactions, 1997, Volume: 25, Issue:2

    Topics: Activating Transcription Factor 2; Animals; Cell Nucleus; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Heart Ventricles; Leucine Zippers; Myocardium; Okadaic Acid; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-jun; Rats; Sorbitol; Stress, Physiological; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

1997
Role of protein kinases in the in vitro differentiation of human epidermal HaCaT cells.
    The British journal of dermatology, 1997, Volume: 137, Issue:1

    Topics: Adenine; Cell Differentiation; Cell Line; Enzyme Inhibitors; Epidermal Cells; Epidermis; Genistein; Humans; Indoles; Isoenzymes; Isoflavones; Keratinocytes; Maleimides; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate

1997
Spontaneous Mn2+ entry is specifically inhibited by calyculin A in human leukemic HL-60 cells.
    European journal of pharmacology, 1997, Jul-23, Volume: 331, Issue:2-3

    Topics: Calcium; Colforsin; Depression, Chemical; Dimethyl Sulfoxide; Enzyme Inhibitors; HL-60 Cells; Humans; Manganese; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1997
Novel biological response modifiers: phthalimides with tumor necrosis factor-alpha production-regulating activity.
    Journal of medicinal chemistry, 1997, Aug-29, Volume: 40, Issue:18

    Topics: Cell Survival; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Immunologic Factors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Okadaic Acid; Optical Rotation; Phthalimides; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1997
Effects of inhibitors of signal transduction pathways on transforming growth factor beta1 and osteogenic protein-1-induced insulinlike growth factor binding protein-3 expression in human bone cells.
    Journal of cellular physiology, 1997, Volume: 173, Issue:1

    Topics: Bone and Bones; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cells, Cultured; Culture Media, Conditioned; Gene Expression Regulation; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 3; Isoflavones; Okadaic Acid; Osteoblasts; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Vanadates

1997
Control of the mutagenicity of aromatic amines by protein kinases and phosphatases. I. The protein phosphatase inhibitors okadaic acid and ortho-vanadate drastically reduce the mutagenicity of aromatic amines.
    Archives of toxicology, 1997, Volume: 71, Issue:10

    Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Biotransformation; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Enzyme Inhibitors; Fluorenes; Liver; Male; Mutagenicity Tests; Mutagens; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vanadates

1997
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
    Histochemistry and cell biology, 1997, Volume: 108, Issue:3

    Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate

1997
Role of protein kinase C-alpha in activation of ecto-5'-nucleotidase in the preconditioned canine myocardium.
    Biochemical and biophysical research communications, 1997, Oct-09, Volume: 239, Issue:1

    Topics: Adenosine Triphosphatases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Transport; Blood Pressure; Cell Membrane; Dogs; Enzyme Activation; Enzyme Inhibitors; Heart Rate; Indoles; Ischemic Preconditioning, Myocardial; Isoenzymes; Maleimides; Methoxamine; Myocardium; Okadaic Acid; Prazosin; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate

1997
Okadaic acid interferes with phorbol-ester-mediated down-regulation of protein kinase C-alpha, C-delta and C-epsilon.
    European journal of biochemistry, 1997, Oct-01, Volume: 249, Issue:1

    Topics: Animals; Down-Regulation; Immunoblotting; Isoenzymes; Okadaic Acid; PC12 Cells; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Subcellular Fractions; Tetradecanoylphorbol Acetate

1997
Relocation of annexin V to platelet membranes is a phosphorylation-dependent process.
    The Biochemical journal, 1997, Dec-01, Volume: 328 ( Pt 2)

    Topics: Adenosine Triphosphate; Alkaline Phosphatase; Annexin A5; Biological Transport; Blood Platelets; Calcimycin; Cell Compartmentation; Humans; Membranes; Okadaic Acid; Phosphoproteins; Phosphorylation; Platelet Activation; Protein Binding; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate

1997
Differential intracellular regulation of cortical GABA(A) and spinal glycine receptors in cultured neurons.
    Brain research, 1997, Sep-26, Volume: 769, Issue:2

    Topics: Aluminum Compounds; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Electric Conductivity; Fluorides; Intracellular Membranes; Mice; Mice, Inbred C57BL; Neurons; Okadaic Acid; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Tetradecanoylphorbol Acetate

1997
Sanguinarine (pseudochelerythrine) is a potent inhibitor of NF-kappaB activation, IkappaBalpha phosphorylation, and degradation.
    The Journal of biological chemistry, 1997, Nov-28, Volume: 272, Issue:48

    Topics: Alkaloids; Benzophenanthridines; Cell Compartmentation; Cell Line; Ceramides; Dithiothreitol; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Interleukin-1; Isoquinolines; NF-kappa B; Okadaic Acid; Phosphorylation; Proto-Oncogene Proteins; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Tumor Necrosis Factor-alpha

1997
Relationships of subunits of type-1 serine/threonine protein phosphatase to morphology and aggregation of B cells.
    Journal of biochemistry, 1997, Volume: 122, Issue:4

    Topics: Animals; B-Lymphocytes; Blotting, Western; Catalysis; Cell Aggregation; Cell Line; Humans; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1997
Tumor necrosis factor-alpha production-inhibiting activity of phthalimide analogues on human leukemia THP-1 cells and a structure-activity relationship study.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:11

    Topics: Drug Screening Assays, Antitumor; Humans; Leukemia, Monocytic, Acute; Okadaic Acid; Phthalimides; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1997
Intestinal trefoil factor induces inactivation of extracellular signal-regulated protein kinase in intestinal epithelial cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jan-06, Volume: 95, Issue:1

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Growth Substances; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mucins; Muscle Proteins; Neuropeptides; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Trefoil Factor-2; Trefoil Factor-3; Vanadates

1998
Phosphorylation and regulation of antidepressant-sensitive serotonin transporters.
    The Journal of biological chemistry, 1998, Jan-23, Volume: 273, Issue:4

    Topics: Carrier Proteins; Cell Line; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Weight; Nerve Tissue Proteins; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Second Messenger Systems; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Tetradecanoylphorbol Acetate

1998
Store-operated Ca2+ entry in insulin-releasing pancreatic beta-cells.
    Cell calcium, 1997, Volume: 22, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cells, Cultured; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Gallopamil; Genistein; Insulin; Islets of Langerhans; Lanthanum; Manganese; Mice; Mice, Obese; Okadaic Acid; Pancreas; Phosphoprotein Phosphatases; Protein-Tyrosine Kinases; Strontium; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors

1997
Regulation of prostaglandin H2 synthase-2 expression in primary human amnion cells by tyrosine kinase dependent mechanisms.
    Biochimica et biophysica acta, 1998, Mar-06, Volume: 1391, Issue:1

    Topics: Amnion; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Gene Expression Regulation; Humans; In Situ Hybridization; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Mitogen-Activated Protein Kinases; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate

1998
Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression.
    Archives of biochemistry and biophysics, 1998, Apr-01, Volume: 352, Issue:1

    Topics: Biological Transport, Active; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Genistein; Humans; Hydroquinones; I-kappa B Proteins; Interleukin-1; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Necrosis Factor-alpha

1998
The role of calcium and phosphorylation of cytosolic phospholipase A2 in regulating arachidonic acid release in macrophages.
    The Journal of biological chemistry, 1998, Apr-03, Volume: 273, Issue:14

    Topics: Animals; Arachidonic Acid; Calcium; Cells, Cultured; Macrophage Activation; Macrophages, Peritoneal; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan

1998
Prostaglandin endoperoxide H synthase-2 expression in human amnion cells: involvement of tyrosine kinases in the regulation.
    Advances in experimental medicine and biology, 1997, Volume: 433

    Topics: Amnion; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cycloheximide; Cyclooxygenase 2; Enzyme Induction; Epidermal Growth Factor; Female; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Membrane Proteins; Mitogen-Activated Protein Kinases; Okadaic Acid; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1997
Inhibition of p130cas tyrosine phosphorylation by calyculin A.
    Journal of leukocyte biology, 1998, Volume: 63, Issue:5

    Topics: Cell Aggregation; Crk-Associated Substrate Protein; Enzyme Inhibitors; Humans; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Kinases; Protein Tyrosine Phosphatases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Protozoan Proteins; Retinoblastoma-Like Protein p130; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway.
    Molecular carcinogenesis, 1998, Volume: 21, Issue:4

    Topics: Base Sequence; Benzoquinones; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Dactinomycin; DNA, Complementary; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Genistein; Humans; Hydroquinones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; NF-kappa B; Okadaic Acid; Phenols; Proto-Oncogene Proteins c-raf; Quinones; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription Factor AP-1; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1998
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
    Experimental eye research, 1998, Volume: 66, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

1998
ZmcPKC70, a protein kinase C-type enzyme from maize. Biochemical characterization, regulation by phorbol 12-myristate 13-acetate and its possible involvement in nitrate reductase gene expression.
    The Journal of biological chemistry, 1998, Jul-24, Volume: 273, Issue:30

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Chromatography, Gel; Diglycerides; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Enzymologic; Histones; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lipid Metabolism; Nitrate Reductase; Nitrate Reductases; Okadaic Acid; Phosphatidylserines; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zea mays

1998
Taurine might be acting as a trophic factor in the retina by modulating phosphorylation of cellular proteins.
    Journal of neuroscience research, 1998, Aug-01, Volume: 53, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Eye Proteins; Goldfish; Growth Substances; Indoles; Lactams; Marine Toxins; Okadaic Acid; Optic Nerve; Oxazoles; Phorbol 12,13-Dibutyrate; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Retina; Sulfonamides; Tamoxifen; Taurine; Tetradecanoylphorbol Acetate

1998
Transcription of alpha2 integrin gene in osteosarcoma cells is enhanced by tumor promoters.
    Experimental cell research, 1998, Aug-25, Volume: 243, Issue:1

    Topics: Antigens, CD; Blotting, Northern; Carcinogens; Cell Adhesion; Collagen; Collagenases; Flow Cytometry; Humans; Integrin alpha2; Integrin alpha3; Integrin alpha5; Integrin alphaV; Integrin beta1; Integrins; Matrix Metalloproteinase 1; Okadaic Acid; Osteosarcoma; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation

1998
Regulation of expression of the DNA repair gene O6-methylguanine-DNA methyltransferase via protein kinase C-mediated signaling.
    Cancer research, 1998, Sep-01, Volume: 58, Issue:17

    Topics: Alkylating Agents; DNA Repair; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; O(6)-Methylguanine-DNA Methyltransferase; Okadaic Acid; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

1998
IL-13 suppresses TNF-induced activation of nuclear factor-kappa B, activation protein-1, and apoptosis.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Sep-15, Volume: 161, Issue:6

    Topics: Apoptosis; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytotoxicity, Immunologic; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Humans; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; Interleukin-13; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Identification of phosphorylation sites on AChR delta-subunit associated with dispersal of AChR clusters on the surface of muscle cells.
    Biochemistry, 1998, Oct-20, Volume: 37, Issue:42

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cell Membrane; Cells, Cultured; Chick Embryo; Cyclic AMP-Dependent Protein Kinases; Molecular Sequence Data; Muscle, Skeletal; Octoxynol; Okadaic Acid; Peptide Mapping; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Tetradecanoylphorbol Acetate

1998
Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors.
    Journal of virology, 1998, Volume: 72, Issue:12

    Topics: Base Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; DNA-Binding Proteins; Gene Expression; Genes, Viral; Hepacivirus; Humans; Hydrogen Peroxide; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligodeoxyribonucleotides; Protein Kinases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transfection; Tumor Necrosis Factor-alpha; Viral Core Proteins

1998
Alterations in cholesterol sulfate and its biosynthetic enzyme during multistage carcinogenesis in mouse skin.
    The Journal of investigative dermatology, 1998, Volume: 111, Issue:6

    Topics: Administration, Topical; Animals; Anthracenes; Anticarcinogenic Agents; Carcinogens; Cell Differentiation; Cell Division; Cholesterol Esters; Dehydroepiandrosterone Sulfate; Epidermis; Female; Keratinocytes; Mice; Mice, Inbred SENCAR; Mice, Transgenic; Okadaic Acid; Skin Neoplasms; Sulfotransferases; Tetradecanoylphorbol Acetate; Transglutaminases; Wound Healing

1998
Selective inhibition of NF-kappaB activation by the flavonoid hepatoprotector silymarin in HepG2. Evidence for different activating pathways.
    FEBS letters, 1998, Nov-27, Volume: 440, Issue:1-2

    Topics: DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Lipopolysaccharides; Liver; NF-kappa B; Okadaic Acid; Protective Agents; Silymarin; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Transcriptional interferences between normal or mutant androgen receptors and the activator protein 1--dissection of the androgen receptor functional domains.
    Endocrinology, 1999, Volume: 140, Issue:1

    Topics: Aldehyde Reductase; Androgens; Animals; Breast Neoplasms, Male; COS Cells; DNA; Enzyme Inhibitors; Genes, Reporter; Genetic Engineering; Humans; Luciferases; Male; Marine Toxins; Mice; Mutation; Okadaic Acid; Oxazoles; Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Androgen; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection

1999
Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Aniline Compounds; Biological Transport; Cell Nucleus; Ceramides; Chloramphenicol O-Acetyltransferase; Crotonates; Dithiothreitol; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; Genes, MDR; Genes, Reporter; Host Cell Factor C1; Humans; Hydrogen Peroxide; Hydroxybutyrates; I-kappa B Proteins; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lipopolysaccharides; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitogen-Activated Protein Kinase Kinases; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Nitriles; Octamer Transcription Factor-1; Okadaic Acid; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Tetradecanoylphorbol Acetate; Toluidines; Transcription Factor AP-1; Transcription Factor RelA; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1999
A role for phosphorylation in the dynamics of keratin intermediate filaments.
    European journal of cell biology, 1999, Volume: 78, Issue:1

    Topics: Adenine; Blotting, Western; Cell Line; Cytoskeleton; Densitometry; Fluorescent Antibody Technique; Intermediate Filaments; Keratins; Okadaic Acid; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transfection

1999
NHE2 contains subdomains in the COOH terminus for growth factor and protein kinase regulation.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Animals; Cattle; Cell Line; Cloning, Molecular; Cricetinae; Cricetulus; Fibroblast Growth Factors; Hydrogen-Ion Concentration; Kinetics; Lung; Mutagenesis, Site-Directed; Okadaic Acid; Protein Kinases; Recombinant Proteins; Sequence Deletion; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection

1999
MAP kinase activity is downregulated by phorbol ester during mouse oocyte maturation and egg activation in vitro.
    Molecular reproduction and development, 1999, Volume: 52, Issue:3

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Female; Fertilization in Vitro; Humans; Interphase; Meiosis; Metaphase; Mice; Mice, Inbred BALB C; Naphthalenes; Okadaic Acid; Oocytes; Oogenesis; Ovum; Phosphoprotein Phosphatases; Protein Kinase C; Tetradecanoylphorbol Acetate

1999
The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
    Molecular and cellular endocrinology, 1999, Feb-25, Volume: 148, Issue:1-2

    Topics: Animals; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Colforsin; Enzyme Inhibitors; Glucose; Homeostasis; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Compounds; Sorbitol; Tetradecanoylphorbol Acetate; Vanadates

1999
TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Acetylcysteine; Blotting, Northern; Calcimycin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Interleukin-1; Ionophores; Marine Toxins; Membrane Proteins; Okadaic Acid; Oxazoles; Phospholipases A; Phospholipases A2; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins

1999
Selective inhibition of protein kinase C isozymes by Fas ligation.
    The Journal of biological chemistry, 1999, May-28, Volume: 274, Issue:22

    Topics: Animals; Antibodies; Apoptosis; Cell Division; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Humans; Isoenzymes; Jurkat Cells; Kinetics; Membrane Glycoproteins; Mice; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Signal Transduction; Tetradecanoylphorbol Acetate

1999
Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice.
    Molecular carcinogenesis, 1999, Volume: 25, Issue:2

    Topics: Animals; Anthracenes; Benzoyl Peroxide; Carcinogens; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Mice; Mice, Transgenic; Okadaic Acid; Receptor, IGF Type 1; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes

1999
Inhibition of p38 MAP kinase increases okadaic acid mediated AP-1 expression and DNA binding but has no effect on TRE dependent transcription.
    Oncogene, 1999, Jun-17, Volume: 18, Issue:24

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Consensus Sequence; DNA; DNA-Binding Proteins; Enzyme Activation; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keratinocytes; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation

1999
Transcriptional regulation of a receptor protein tyrosine phosphatase gene hPTP-J by PKC-mediated signaling pathways in Jurkat and Molt-4 T lymphoma cells.
    Biochimica et biophysica acta, 1999, Jul-08, Volume: 1450, Issue:3

    Topics: Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; HL-60 Cells; Humans; Jurkat Cells; Okadaic Acid; Protein Kinase C; Protein Tyrosine Phosphatases; ras Proteins; Receptors, Cell Surface; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

1999
Different sensitivities of p42 mitogen-activated protein kinase to phorbol ester and okadaic acid tumor promoters among cell types.
    Biochemical pharmacology, 1999, Jul-15, Volume: 58, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Cell Line; Fibroblasts; HeLa Cells; Humans; Mice; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphorylation; Tetradecanoylphorbol Acetate

1999
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts.
    The Journal of biological chemistry, 1999, Aug-27, Volume: 274, Issue:35

    Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatin; Epidermal Growth Factor; Fluorescent Antibody Technique; Gene Expression Regulation; Genes, fos; Genes, myc; Genes, ras; Histones; Mice; Mitogens; Okadaic Acid; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transformation, Genetic

1999
Ceramide synergizes with phorbol ester or okadaic acid to induce IkappaB degradation.
    Biochemical and biophysical research communications, 1999, Sep-16, Volume: 263, Issue:1

    Topics: Animals; Cell Line; Ceramides; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Protein Kinase C; Second Messenger Systems; Sphingomyelin Phosphodiesterase; T-Lymphocytes; Tetradecanoylphorbol Acetate; Theileria parva

1999
Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.
    Cancer research, 1999, Sep-15, Volume: 59, Issue:18

    Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line, Transformed; Female; Genes, ras; Interleukin-1; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Okadaic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

1999
Phosphorylated form of MacMARCKS is essential to LFA-1-dependent cell-cell adhesion of U937 monocytic cells.
    Journal of cellular physiology, 1999, Volume: 181, Issue:2

    Topics: Animals; Calmodulin-Binding Proteins; Cell Adhesion; DNA, Complementary; Humans; Intracellular Signaling Peptides and Proteins; Lymphocyte Function-Associated Antigen-1; Membrane Proteins; Mice; Microfilament Proteins; Okadaic Acid; Phosphorylation; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; U937 Cells

1999
On the lysosomal degradation of neurofibromin and its phosphorylation in cultured melanocytes.
    Biological chemistry, 1999, Volume: 380, Issue:9

    Topics: Animals; Cells, Cultured; Chloroquine; Enzyme Inhibitors; Half-Life; Humans; Lysosomes; Melanocytes; Molecular Sequence Data; Neurofibromin 1; Okadaic Acid; Phosphorylation; Proteins; Rats; Tetradecanoylphorbol Acetate

1999
Silymarin suppresses TNF-induced activation of NF-kappa B, c-Jun N-terminal kinase, and apoptosis.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Dec-15, Volume: 163, Issue:12

    Topics: Apoptosis; Binding Sites; Ceramides; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Enzyme Activation; Enzyme Repression; Genes, Reporter; HeLa Cells; Humans; I-kappa B Proteins; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Lipid Peroxidation; Lipopolysaccharides; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Silymarin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha; U937 Cells

1999
Ceramide-induced apoptosis in fas-resistant Hodgkin's disease cell lines is caspase independent.
    Experimental cell research, 2000, Feb-25, Volume: 255, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; bcl-X Protein; Caspase 1; Caspase 3; Caspase Inhibitors; Caspases; CD40 Antigens; Cell Membrane Permeability; Ceramides; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Gene Expression; Hodgkin Disease; Humans; Membrane Glycoproteins; Okadaic Acid; Oligopeptides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

2000
Protein phosphatase-protein kinase interplay modulates alpha 1b-adrenoceptor phosphorylation: effects of okadaic acid.
    British journal of pharmacology, 2000, Volume: 129, Issue:4

    Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Pyrans; Pyrethrins; Rats; Receptors, Adrenergic, alpha-1; Spiro Compounds; Staurosporine; Tetradecanoylphorbol Acetate

2000
Transient translocation and activation of protein phosphatase 2A during mast cell secretion.
    The Journal of biological chemistry, 2000, Mar-03, Volume: 275, Issue:9

    Topics: Animals; Antigens; beta-N-Acetylhexosaminidases; Calcimycin; Cell Line; Dinitrophenols; Enzyme Activation; Immunoglobulin E; Marine Toxins; Mast Cells; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Rats; Serum Albumin, Bovine; Signal Transduction; Tetradecanoylphorbol Acetate

2000
A protein kinase C-independent pathway leading to c-Jun-dependent expression of 100-kDa Ras GTPase-activating protein in JEG-3 human choriocarcinoma cells.
    European journal of biochemistry, 2000, Volume: 267, Issue:6

    Topics: Cell Differentiation; Choriocarcinoma; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Weight; Neoplasm Proteins; Okadaic Acid; Oligonucleotides, Antisense; Protein Isoforms; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; ras GTPase-Activating Proteins; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Neoplasms

2000
Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells.
    The Journal of biological chemistry, 2000, Apr-07, Volume: 275, Issue:14

    Topics: Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cell Line; Kidney; Kinetics; Mice; Okadaic Acid; p-Aminohippuric Acid; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-myc; Recombinant Fusion Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

2000
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4.
    The Journal of biological chemistry, 2000, Apr-07, Volume: 275, Issue:14

    Topics: 3T3 Cells; ADAM Proteins; ADAM17 Protein; Animals; Clone Cells; Cloning, Molecular; Colforsin; Disintegrins; Drosophila Proteins; ErbB Receptors; Kinetics; Marine Toxins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Oxazoles; Protein Isoforms; Receptor, ErbB-4; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Necrosis Factor-alpha; Vanadates

2000
Varied protocols of cadmium exposure produce different effects on nitric oxide production in macrophages.
    Toxicology, 2000, Apr-20, Volume: 146, Issue:1

    Topics: Animals; Blotting, Western; Cadmium; Cell Survival; Formazans; Gene Expression Regulation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Okadaic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazolium Salts

2000
Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition.
    The Journal of biological chemistry, 2000, Jul-14, Volume: 275, Issue:28

    Topics: Burkitt Lymphoma; Cell Cycle; Cell Survival; Enzyme Activation; Enzyme Inhibitors; G2 Phase; Humans; Marine Toxins; Microtubules; Mitogen-Activated Protein Kinases; Mitosis; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Nocodazole; Okadaic Acid; Oxazoles; Paclitaxel; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vinblastine

2000
Cellular proliferation and telomerase activity in CHRF-288-11 cells.
    Life sciences, 2000, Volume: 66, Issue:16

    Topics: Cell Division; Cell Line; Egtazic Acid; Humans; Megakaryocytes; Okadaic Acid; Telomerase; Tetradecanoylphorbol Acetate

2000
Wortmannin inhibits activation of nuclear transcription factors NF-kappaB and activated protein-1 induced by lipopolysaccharide and phorbol ester.
    FEBS letters, 2000, May-04, Volume: 473, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Ceramides; DNA Probes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Proteins; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Organ Specificity; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin

2000
Vesnarinone suppresses TNF-induced activation of NF-kappa B, c-Jun kinase, and apoptosis.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Jun-01, Volume: 164, Issue:11

    Topics: Apoptosis; Biological Transport; Ceramides; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Genes, MDR; Genes, Reporter; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Lipid Peroxidation; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Protein Binding; Pyrazines; Quinolines; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha; U937 Cells; Uridine

2000
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Jun-15, Volume: 164, Issue:12

    Topics: Apoptosis; Biological Transport; Caspase Inhibitors; Cell Line; Cell Nucleus; Ceramides; Cytotoxicity, Immunologic; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Lipopolysaccharides; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2000
Inhibition and stimulation of growth of Entamoeba histolytica in culture: association with PKC activity and protein phosphorylation.
    Experimental parasitology, 2000, Volume: 95, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Culture Media; Down-Regulation; Entamoeba histolytica; Enzyme Inhibitors; Indoles; Maleimides; Marine Toxins; Okadaic Acid; Oxazoles; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine

2000
Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Animals; Anisomycin; Arachidonic Acid; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NADPH Oxidases; Okadaic Acid; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Synthesis Inhibitors; Serine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan

2000
Estrogen directly acts on osteoclasts via inhibition of inward rectifier K+ channels.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: Animals; Barium; Calcium; Cells, Cultured; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Estradiol; Guanosine Diphosphate; Membrane Potentials; Okadaic Acid; Osteoclasts; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Progesterone; Rats; Rats, Wistar; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors

2000
Phosphatase inhibitors and premature chromosome condensation in human peripheral lymphocytes at different cell-cycle phases.
    Somatic cell and molecular genetics, 1999, Volume: 25, Issue:1

    Topics: Calcimycin; Cell Cycle; Chromosomes, Human; Enzyme Inhibitors; Humans; Ionophores; Lymphocytes; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate

1999
Okadaic acid suppresses TPA-induced differentiation by stimulating G1/S transition in human myeloblastic leukaemia ML-1 cells.
    Cell proliferation, 2000, Volume: 33, Issue:4

    Topics: Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; G1 Phase; Humans; Leukemia, Myeloid, Acute; Lipopolysaccharide Receptors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Retinoblastoma Protein; S Phase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts.
    Current biology : CB, 2000, Oct-19, Volume: 10, Issue:20

    Topics: Animals; Biological Clocks; Bucladesine; Calcimycin; Cell Cycle Proteins; Cell Line; Circadian Rhythm; Colforsin; Culture Media; Dimethyl Sulfoxide; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Insulin; Nuclear Proteins; Okadaic Acid; Period Circadian Proteins; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

2000
Filopodial behavior is dependent on the phosphorylation state of neuronal growth cones.
    Cell motility and the cytoskeleton, 2000, Volume: 47, Issue:4

    Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Carrier Proteins; Cells, Cultured; Cerebrosides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Genistein; Growth Cones; Indole Alkaloids; Intracellular Signaling Peptides and Proteins; Models, Biological; Myosin-Light-Chain Kinase; Naphthalenes; Neurons; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pseudopodia; Signal Transduction; Snails; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Vanadates

2000
Enhancing effect of tumor promoters, phorbol esters and teleocidins on nuclear receptor-mediated transcription.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: Animals; Carcinogens; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Lactams; Luciferases; Lyngbya Toxins; Nuclear Receptor Subfamily 1, Group F, Member 1; Okadaic Acid; Plasmids; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Tetradecanoylphorbol Acetate; Thapsigargin; Thymidine Kinase; Trans-Activators; Transcription, Genetic; Transfection

2000
Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor.
    Journal of neurochemistry, 2001, Volume: 76, Issue:3

    Topics: Amino Acid Sequence; Animals; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Okadaic Acid; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine

2001
p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization.
    Biochemical and biophysical research communications, 2001, Jan-12, Volume: 280, Issue:1

    Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Kinetics; Luciferases; Maleimides; Okadaic Acid; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Suppressor Protein p53; U937 Cells

2001
Down-regulation of Na-K-Cl cotransport by protein kinase C is mediated by protein phosphatase 1 in pigmented ciliary epithelial cells.
    Experimental eye research, 2001, Volume: 72, Issue:4

    Topics: Carcinogens; Cells, Cultured; Chloride Channels; Ciliary Body; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; Maleimides; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Pigment Epithelium of Eye; Potassium Channels; Protein Kinase C; Protein Phosphatase 1; Rubidium Radioisotopes; Sodium Channels; Staurosporine; Tetradecanoylphorbol Acetate

2001
Protein kinase C modulates NMDA receptor trafficking and gating.
    Nature neuroscience, 2001, Volume: 4, Issue:4

    Topics: Animals; Botulinum Toxins, Type A; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Exocytosis; Hippocampus; Ion Channel Gating; Membrane Proteins; Microscopy, Fluorescence; N-Methylaspartate; Nerve Tissue Proteins; Neuromuscular Agents; Neurons; Okadaic Acid; Oocytes; Patch-Clamp Techniques; Protein Kinase C; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate; Xenopus

2001
Phosphorylation of mitogen-activated protein kinase is regulated by protein kinase C, cyclic 3',5'-adenosine monophosphate, and protein phosphatase modulators during meiosis resumption in rat oocytes.
    Biology of reproduction, 2001, Volume: 64, Issue:5

    Topics: Animals; Blotting, Western; Cyclic AMP; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Kinetics; Meiosis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2001
12-O-tetradecanoylphorbol-13-acetate induces apoptosis in renal epithelial cells through a growth signal conflict which is prevented by activated ras.
    Archives of biochemistry and biophysics, 2001, Jan-15, Volume: 385, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Bryostatins; Caspase 3; Caspases; Cell Cycle Proteins; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Enzyme Activation; Epithelial Cells; Genes, ras; Kidney; Lactones; Macrolides; Microtubule-Associated Proteins; Okadaic Acid; Oncogene Protein p21(ras); Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Retinoblastoma Protein; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins

2001
Modulation of arachidonic acid turnover in macrophages by cadmium.
    Toxicology letters, 2001, May-31, Volume: 122, Issue:1

    Topics: Animals; Arachidonic Acids; Cadmium; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Okadaic Acid; Oxidation-Reduction; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Time Factors; Zymosan

2001
Phorbol myristate acetate inhibits okadaic acid-induced apoptosis and downregulation of X-linked inhibitor of apoptosis in U937 cells.
    Biochemical and biophysical research communications, 2001, Sep-14, Volume: 287, Issue:1

    Topics: Apoptosis; Carcinogens; Caspase 3; Caspases; Down-Regulation; Drug Interactions; Enzyme Induction; Humans; Isoenzymes; Okadaic Acid; Phospholipase C gamma; Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Type C Phospholipases; U937 Cells; X-Linked Inhibitor of Apoptosis Protein

2001
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells.
    Toxicology, 2001, Oct-15, Volume: 167, Issue:2

    Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin

2001
The antitumour agent 5,6-dimethylxanthenone-4-acetic acid acts in vitro on human mononuclear cells as a co-stimulator with other inducers of tumour necrosis factor.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:15

    Topics: Antineoplastic Agents; Cell Culture Techniques; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; NF-kappa B; Okadaic Acid; Salicylic Acid; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

2001
Heterogeneity in the phosphorylation of human death receptors by p42(mapk/erk2).
    Biochemical and biophysical research communications, 2001, Oct-26, Volume: 288, Issue:2

    Topics: Animals; Antigens, CD; Consensus Sequence; COS Cells; Cytoplasm; fas Receptor; Humans; Leukocytes, Mononuclear; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Okadaic Acid; Phosphoamino Acids; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 25; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Tetradecanoylphorbol Acetate

2001
Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells.
    FEBS letters, 2001, Oct-19, Volume: 507, Issue:1

    Topics: Acetylation; Base Sequence; Breast Neoplasms; Chromatin; DNA Primers; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Effect of Leishmania donovani lipophosphoglycan on ornithine decarboxylase activity in macrophages.
    The Journal of parasitology, 2001, Volume: 87, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Bacterial Agents; Bucladesine; Calcimycin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glycosphingolipids; Leishmania donovani; Leishmaniasis, Visceral; Lipopolysaccharides; Macrophages; Mice; Okadaic Acid; Ornithine Decarboxylase; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

2001
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
    International journal of oncology, 2002, Volume: 20, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Humans; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

2002
14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.
    Molecular endocrinology (Baltimore, Md.), 2002, Volume: 16, Issue:3

    Topics: 14-3-3 Proteins; 3T3 Cells; Animals; Biological Transport; Cell Nucleus; COS Cells; Cytoplasm; Cytosol; Enzyme Inhibitors; Epidermal Growth Factor; Fluorescent Antibody Technique; Immunosorbent Techniques; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Mice; Microscopy, Confocal; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase

2002
Thalidomide suppresses NF-kappa B activation induced by TNF and H2O2, but not that activated by ceramide, lipopolysaccharides, or phorbol ester.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Mar-15, Volume: 168, Issue:6

    Topics: Antigens, CD; Cell Line; Ceramides; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation; Genes, Reporter; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Immunosuppressive Agents; Jurkat Cells; Kidney; Lipopolysaccharides; Myeloid Cells; NF-kappa B; NF-KappaB Inhibitor alpha; NF-kappaB-Inducing Kinase; Okadaic Acid; Protein Serine-Threonine Kinases; Proteins; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tetradecanoylphorbol Acetate; Thalidomide; TNF Receptor-Associated Factor 2; Tumor Necrosis Factor-alpha; U937 Cells

2002
Protein phosphatases 1 and 2A transiently associate with myosin during the peak rate of secretion from mast cells.
    Molecular biology of the cell, 2002, Volume: 13, Issue:3

    Topics: Actins; Animals; Antineoplastic Agents; Calcimycin; Cell Line; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Depsipeptides; Enzyme Inhibitors; Exocytosis; Immunoglobulin E; Ionophores; Mast Cells; Myosins; Okadaic Acid; Peptide Mapping; Peptides, Cyclic; Phosphoprotein Phosphatases; Rats; Tetradecanoylphorbol Acetate

2002
Eicosapentaenoic acid and docosahexaenoic acid modulate MAP kinase enzyme activity in human T-cells.
    Molecular and cellular biochemistry, 2002, Volume: 232, Issue:1-2

    Topics: Antibodies; CD3 Complex; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Activation; Fatty Acids, Unsaturated; Humans; Jurkat Cells; Mitogen-Activated Protein Kinases; Okadaic Acid; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate

2002
Regulation of retinoid X receptor responsive element-dependent transcription in T lymphocytes by Ser/Thr phosphatases: functional divergence of protein kinase C (PKC)theta; and PKC alpha in mediating calcineurin-induced transactivation.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Jul-15, Volume: 169, Issue:2

    Topics: Calcineurin; Calcineurin Inhibitors; Drug Synergism; Enzyme Inhibitors; Humans; Isoenzymes; Jurkat Cells; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-theta; Protein Phosphatase 1; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transcriptional Activation

2002
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.
    Blood, 2002, Nov-01, Volume: 100, Issue:9

    Topics: Adult; Agatoxins; Alkaloids; Benzophenanthridines; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Cell Size; Diglycerides; Dimethyl Sulfoxide; Enzyme Inhibitors; Erythrocytes; Humans; Ion Transport; Ionophores; Marine Toxins; Okadaic Acid; Osmotic Fragility; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Protein Kinase C; Spider Venoms; Staurosporine; Tetradecanoylphorbol Acetate

2002
Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylation.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Dec-01, Volume: 169, Issue:11

    Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Cell Line; Ceramides; Cyclin D1; Cyclooxygenase 2; DNA; Enzyme Inhibitors; Enzyme Precursors; Gene Expression; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Kinase; Intracellular Signaling Peptides and Proteins; Isoenzymes; Jurkat Cells; Lipopolysaccharides; Matrix Metalloproteinase 9; Membrane Proteins; NF-kappa B; Okadaic Acid; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Stilbenes; Syk Kinase; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2002
Protein phosphatase 2A enhances activation of human immunodeficiency virus type 1 by phorbol myristate acetate.
    Journal of virology, 2003, Volume: 77, Issue:3

    Topics: Alkenes; HIV-1; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Polyenes; Promoter Regions, Genetic; Protein Kinase C; Protein Phosphatase 2; Pyrones; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells; Virus Activation

2003
Adenosine suppresses activation of nuclear factor-kappaB selectively induced by tumor necrosis factor in different cell types.
    Oncogene, 2003, Feb-27, Volume: 22, Issue:8

    Topics: Adenosine; Alkaline Phosphatase; Antigens, CD; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; Genes, Reporter; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Jurkat Cells; Kidney; Leukemia, Myeloid; Lipopolysaccharides; Monocytes; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; NF-kappaB-Inducing Kinase; Okadaic Acid; Protein Serine-Threonine Kinases; Proteins; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thymidine; TNF Receptor-Associated Factor 2; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Uridine

2003
Immunosuppression in hamsters with progressive visceral leishmaniasis is associated with an impairment of protein kinase C activity in their lymphocytes that can be partially reversed by okadaic acid or anti-transforming growth factor beta antibody.
    Infection and immunity, 2003, Volume: 71, Issue:5

    Topics: Animals; Cricetinae; Immune Tolerance; Immunoblotting; Leishmaniasis, Visceral; Lymphocyte Activation; Lymphocytes; Okadaic Acid; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

2003
CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 285, Issue:4

    Topics: Alkenes; Animals; Binding Sites; Calcineurin Inhibitors; Calcium; Cholecystokinin; Cyclic AMP; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Polyenes; Pyrones; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

2003
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway.
    The Journal of biological chemistry, 2003, Sep-05, Volume: 278, Issue:36

    Topics: Androstadienes; Apoptosis; Blotting, Western; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostatic Neoplasms; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA Interference; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured; Wortmannin

2003
Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Sep-15, Volume: 171, Issue:6

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Caco-2 Cells; Carcinogens; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Kinase; Interleukin-1; Isoenzymes; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; NF-kappa B; Nicotiana; Okadaic Acid; Pentacyclic Triterpenes; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Smoke; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Triterpenes; Tumor Necrosis Factor-alpha

2003
Identification of two distinct pathways of protein kinase Calpha down-regulation in intestinal epithelial cells.
    The Journal of biological chemistry, 2004, Feb-13, Volume: 279, Issue:7

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Bryostatins; Calpain; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Intestinal Mucosa; Lactones; Macrolides; Marine Toxins; Microscopy, Fluorescence; Models, Biological; Multienzyme Complexes; Okadaic Acid; Oxazoles; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Kinase C-alpha; Rats; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Ubiquitin

2004
PKC alpha is activated but not required during glucose-induced insulin secretion from rat pancreatic islets.
    Diabetes, 2004, Volume: 53, Issue:1

    Topics: Adenoviridae; Animals; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Models, Animal; Okadaic Acid; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Rats, Wistar; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

2004
Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis.
    The Journal of biological chemistry, 2004, Apr-09, Volume: 279, Issue:15

    Topics: Active Transport, Cell Nucleus; Alkaline Phosphatase; Amino Acid Sequence; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Nucleus; Cell-Free System; Coloring Agents; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; In Situ Nick-End Labeling; Interleukin-1; Lipopolysaccharides; Microscopy, Phase-Contrast; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Peptide Fragments; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Transcription Factor RelA; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation

2004
Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    The Biochemical journal, 2004, May-01, Volume: 379, Issue:Pt 3

    Topics: Astrocytoma; Calcium; Carbachol; Cell Line, Tumor; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Insulin; Insulin Receptor Substrate Proteins; Ionomycin; Mitogen-Activated Protein Kinases; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Muscarinic; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases

2004
Increase of metabolic activity and disruption of normal contractile protein distribution by bilirubin oxidation products in vascular smooth-muscle cells.
    Journal of neurosurgery, 2004, Volume: 100, Issue:3

    Topics: Animals; Carrier Proteins; Contractile Proteins; Disease Models, Animal; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Muscle, Smooth, Vascular; Okadaic Acid; Oxidoreductases Acting on CH-CH Group Donors; Proteins; Subarachnoid Hemorrhage; Swine; Tetradecanoylphorbol Acetate; Vasospasm, Intracranial

2004
Mitogen-activated protein kinase phosphatase-3 is a tumor promoter target in initiated cells that express oncogenic Ras.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Acrylamides; Animals; Breast Neoplasms; Carcinogens; Cell Line; Cnidarian Venoms; Dual Specificity Phosphatase 6; Enzyme Activation; Gene Expression; Genes, ras; Humans; Immunoblotting; Keratinocytes; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinases; Okadaic Acid; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2004
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.
    Oncogene, 2004, Jul-08, Volume: 23, Issue:31

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Carcinogens; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Okadaic Acid; Paclitaxel; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection

2004
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Journal of immunology (Baltimore, Md. : 1950), 2004, Aug-01, Volume: 173, Issue:3

    Topics: Carcinogens; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cell Line, Tumor; Cyclin D1; Cyclooxygenase Inhibitors; Enzyme Activation; Genes, Reporter; Humans; I-kappa B Kinase; I-kappa B Proteins; Interleukin-1; Lipopolysaccharides; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase Inhibitors; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Receptors, Tumor Necrosis Factor; Sulfonamides; Tetradecanoylphorbol Acetate; TNF Receptor-Associated Factor 1; TNF Receptor-Associated Factor 2; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2004
Redox regulation of the calcium/calmodulin-dependent protein kinases.
    The Journal of biological chemistry, 2004, Oct-22, Volume: 279, Issue:43

    Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cysteine; Enzyme Activation; Enzyme Inhibitors; Glucose Oxidase; Humans; Hydrogen Peroxide; Immunoblotting; Immunoprecipitation; Jurkat Cells; Marine Toxins; Microcystins; Okadaic Acid; Oxidation-Reduction; Oxygen; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotransferases; Protein Phosphatase 2; Reactive Oxygen Species; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Time Factors

2004
Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis.
    The Journal of biological chemistry, 2004, Nov-05, Volume: 279, Issue:45

    Topics: Active Transport, Cell Nucleus; Apoptosis; Blotting, Western; Cell Line; Cell Line, Tumor; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Humans; I-kappa B Proteins; Inflammation; Interleukin-1; Isoenzymes; Jurkat Cells; Luciferases; Membrane Proteins; Models, Chemical; Neoplasm Metastasis; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Poly(ADP-ribose) Polymerases; Pregnenediones; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Temperature; Tetradecanoylphorbol Acetate; Transcription, Genetic

2004
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
    Circulation research, 2004, Oct-01, Volume: 95, Issue:7

    Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate

2004
Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.
    Acta biochimica Polonica, 2004, Volume: 51, Issue:3

    Topics: Amiloride; Animals; Arachidonic Acids; Brefeldin A; Cytochrome P-450 Enzyme System; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Kidney Cortex; Kinetics; Male; Models, Biological; Nocodazole; Okadaic Acid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Rats, Wistar; Sodium; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate

2004
Downregulation of protein phosphatase 2A activity in HeLa cells at the G2-mitosis transition and unscheduled reactivation induced by 12-O-tetradecanoyl phorbol-13-acetate (TPA).
    European journal of cell biology, 2005, Volume: 84, Issue:8

    Topics: Antibodies; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; G2 Phase; HeLa Cells; Humans; Mitosis; Okadaic Acid; Peptides; Phosphoprotein Phosphatases; Protein Phosphatase 2; Protein Subunits; Tetradecanoylphorbol Acetate

2005
Okadaic acid increases the phosphorylation state of alpha1A-adrenoceptors and induces receptor desensitization.
    European journal of pharmacology, 2005, Nov-21, Volume: 525, Issue:1-3

    Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Line; Enzyme Inhibitors; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate

2005
Agonist-induced phosphorylation and desensitization of the P2Y2 nucleotide receptor.
    Molecular and cellular biochemistry, 2005, Volume: 280, Issue:1-2

    Topics: Humans; Immunoprecipitation; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Uridine Triphosphate

2005
Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages.
    American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:4

    Topics: Animals; Antigens, CD; Biological Transport; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Choline; Enzyme Inhibitors; Humans; Macrophages; Monocytes; Okadaic Acid; Organic Cation Transport Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate

2006
2-Hydroxyestradiol-17beta-induced oocyte maturation in catfish (Heteropneustes fossilis) involves protein kinase C and its interaction with protein phosphatases.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2006, Volume: 144, Issue:4

    Topics: Animals; Catfishes; Cell Differentiation; Enzyme Inhibitors; Estradiol; Female; Naphthalenes; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate

2006
Lymph node cells from BALB/c mice with chronic visceral leishmaniasis exhibiting cellular anergy and apoptosis: involvement of Ser/Thr phosphatase.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:11

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Proliferation; Chronic Disease; Clonal Anergy; Cricetinae; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ionomycin; Ionophores; Leishmania donovani; Leishmaniasis, Visceral; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate

2006
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.
    The Journal of physiology, 2007, Mar-01, Volume: 579, Issue:Pt 2

    Topics: Animals; Arachidonic Acids; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Granulocytes; Group IV Phospholipases A2; Humans; Indoles; Ion Channels; Maleimides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Okadaic Acid; Phospholipases A; Protein Kinase C; Protons; Signal Transduction; Tetradecanoylphorbol Acetate

2007
Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells.
    Pharmacological research, 2007, Volume: 56, Issue:3

    Topics: Alkaloids; Anti-Inflammatory Agents; Benzophenanthridines; Berberine; Cell Survival; Ceramides; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Humans; Hydrogen Peroxide; I-kappa B Proteins; Inflammation; Interleukin-1beta; Isoquinolines; Lipopolysaccharides; Lung; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells

2007
Activation of epidermal akt by diverse mouse skin tumor promoters.
    Molecular cancer research : MCR, 2007, Volume: 5, Issue:12

    Topics: Animals; Anthracenes; Anticoagulants; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermis; ErbB Receptors; Female; Heparin; Indoles; Keratinocytes; Maleimides; Mice; Mice, Inbred ICR; Okadaic Acid; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.
    Journal of leukocyte biology, 2008, Volume: 84, Issue:3

    Topics: Animals; Arachidonic Acid; Benzoquinones; Calcimycin; Calcium; Carcinogens; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Golgi Apparatus; Green Fluorescent Proteins; Group IV Phospholipases A2; HSP90 Heat-Shock Proteins; Immunoblotting; Immunoprecipitation; Ionophores; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 10; NIH 3T3 Cells; Okadaic Acid; Phosphoamino Acids; Phosphorylation; Protein Transport; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan

2008
Ubiquitination as a priming process of PKC alpha and PKC epsilon degradation in the alphaT3-1 gonadotrope cell line.
    Neuroendocrinology, 2009, Volume: 89, Issue:3

    Topics: Animals; Cell Line; Down-Regulation; Gonadotrophs; Gonadotropin-Releasing Hormone; Isoenzymes; Mice; Okadaic Acid; Oligopeptides; Proteasome Endopeptidase Complex; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Tetradecanoylphorbol Acetate; Ubiquitination

2009
Inhibition of lipopolysaccharide-induced interleukin-1beta and tumor necrosis factor-alpha production by menthone through nuclear factor-kappaB signaling pathway in HaCat cells.
    The Chinese journal of physiology, 2008, Jun-30, Volume: 51, Issue:3

    Topics: Anti-Inflammatory Agents; beta-Transducin Repeat-Containing Proteins; Cell Line; Ceramides; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-1beta; Keratinocytes; Lipopolysaccharides; Medicine, Chinese Traditional; Menthol; NF-kappa B; Okadaic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2008
Comparison of gene expression profiles in BALB/c 3T3 transformed foci exposed to tumor promoting agents.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:2

    Topics: Animals; BALB 3T3 Cells; Cadmium Chloride; Carcinogens; Cell Proliferation; Extracellular Matrix; Gene Expression Profiling; Gene Expression Regulation; Mice; Okadaic Acid; Protein Array Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate

2010
Ser123 is essential for the water channel activity of McPIP2;1 from Mesembryanthemum crystallinum.
    The Journal of biological chemistry, 2010, May-28, Volume: 285, Issue:22

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Aquaporins; Mesembryanthemum; Molecular Sequence Data; Mutagenesis, Site-Directed; Okadaic Acid; Oocytes; Permeability; Plant Proteins; Serine; Tetradecanoylphorbol Acetate; Water; Xenopus laevis

2010
Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:4

    Topics: Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Flow Cytometry; Gossypol; Humans; Intercellular Adhesion Molecule-1; NF-kappa B; Okadaic Acid; Paclitaxel; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells

2011
Activation of MAP kinase family members triggered by TPA or ionomycin occurs via the protein phosphatase 4 pathway in Jurkat leukemia T cells.
    Molecular medicine reports, 2012, Volume: 5, Issue:3

    Topics: Calcium Ionophores; Enzyme Activation; Enzyme Inhibitors; Humans; Ionomycin; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia, T-Cell; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Ultraviolet Rays

2012
Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.
    The Journal of biological chemistry, 2014, Aug-08, Volume: 289, Issue:32

    Topics: Binding Sites; Burkitt Lymphoma; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Marine Toxins; Myeloid Cell Leukemia Sequence 1 Protein; Okadaic Acid; Oxazoles; Phosphorylation; Protein Phosphatase 2; Proteolysis; Serine; Tetradecanoylphorbol Acetate; Threonine

2014
Ceramide inhibits PKCθ by regulating its phosphorylation and translocation to lipid rafts in Jurkat cells.
    Immunologic research, 2016, Volume: 64, Issue:4

    Topics: Cell Proliferation; Ceramides; fas Receptor; Humans; Jurkat Cells; Lymphocyte Activation; Marine Toxins; Membrane Microdomains; Okadaic Acid; Oxazoles; Phosphorylation; Protein Kinase C-theta; Protein Transport; Signal Transduction; Sphingomyelin Phosphodiesterase; T-Lymphocytes; Tetradecanoylphorbol Acetate

2016