tetradecanoylphorbol acetate has been researched along with n-formylmethionine leucyl-phenylalanine in 1268 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 370 (29.18) | 18.7374 |
| 1990's | 684 (53.94) | 18.2507 |
| 2000's | 176 (13.88) | 29.6817 |
| 2010's | 34 (2.68) | 24.3611 |
| 2020's | 4 (0.32) | 2.80 |
| Authors | Studies |
|---|---|
| Raghavan, A; Rathakrishnan, C; Tiku, K; Tiku, ML | 1 |
| Barasoaín, I; Flores, I; García-Sancho, J; Lacal, PM; Mollinedo, F; Sánchez, A | 1 |
| Daigneault, DE; Hartshorn, KL; Tauber, AI; Tauber, JL; Tuvin, M; White, MR | 1 |
| Filep, JG; Földes-Filep, E; Sirois, P | 1 |
| Jin, N; Packer, CS; Patterson, CE; Rhoades, RA | 1 |
| Azuma, E; Kitagawa, S; Motoyoshi, K; Saito, M; Takaku, F; Yuo, A | 1 |
| Akimaru, K; Edashige, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T | 1 |
| Barton, JC; Basford, RE; Berkow, RL; Joyce, RA; Kaplan, SS | 1 |
| Bach, MK; Brashler, JR | 1 |
| Müller, S; Nigam, S; Walzog, B | 1 |
| Franson, RC; Lattanzio, KS; Rosenthal, MD | 1 |
| Becker, EL; Gomez-Cambronero, J; Gomez-Cambronero, TM; Huang, CK; Sha'afi, RI; Waterman, WH | 1 |
| Bernier, JL; Catteau, JP; Cotelle, N; Gaydou, E; Hénichart, JP; Wallet, JC | 1 |
| Akimaru, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T; Yoshioka, T | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Edmondson, DE; Hand, WL; Lambeth, JD; Perry, DK | 1 |
| Douglas, SD; Greer, W; Kilpatrick, L; Korchak, HM; Majumdar, S; McCawley, L; Nachiappan, V | 1 |
| Ashkenazi, M; Dennison, DK; White, RR | 1 |
| Guy, N; Hahn, T; Tabachnik, E; Vaisman, N; Voet, H | 1 |
| Huggler, E; Krause, KH; Lew, DP; Monod, A; van Delden, C | 1 |
| Kishikawa, K; Maruyama, T; Miyamoto, T; Seo, R; Tateishi, N; Toda, M | 1 |
| Davies, B; Edwards, SW | 1 |
| Buth, S; Gahr, M; Jendrossek, V; Stetter, C | 1 |
| Abdalla, DS; Campa, A; Monteiro, HP | 1 |
| Gabler, WL; Smith, J; Tsukuda, N | 1 |
| Harkiss, D; James, K; Kelly, RW; Skibinski, G | 1 |
| Arfors, KE; Berger, E; Lundgren-Akerlund, E | 1 |
| Bessou, G; Halbwachs-Mecarelli, L; Lesavre, P; Porteu, F; Rieu, P | 1 |
| Joyce, DA; Steer, JH | 1 |
| Elsner, J; Emmendörffer, A; Lohmann-Matthes, ML; Roesler, J; Welte, K; Zeidler, C | 1 |
| Chan, CK; Downey, GP; Grinstein, S; Lea, P; Takai, A | 1 |
| Richter, J | 1 |
| Ackerman, SJ; Dvorak, AM; Golightly, LM; Thomas, LL | 1 |
| Cohen, HJ; Currie, MS; Kilby, DL; Peters, WP; Rao, KM | 1 |
| Burton, MJ; Stoehr, SJ; Suchard, SJ | 1 |
| Betts, WH; McLennan, G; Scicchitano, R; Wozniak, A | 1 |
| Heller, DN; Raffin, TA; Schumann, MA; Tanigaki, T | 1 |
| Buschauer, A; Höer, A; Offermanns, S; Schunack, W; Seifert, R | 1 |
| Anfossi, G; Burzacca, S; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Russo, I; Trovati, M | 1 |
| Chabot, MC; Kennerly, DA; McCall, CE; McPhail, LC; Wykle, RL | 1 |
| Joseph, S; MacDermot, J | 1 |
| Graham, GG; Joulianos, G; Rudkowski, R; Ziegler, JB | 1 |
| Kinugasa, T; Kuroki, M; Matsuo, Y; Matsuoka, Y | 1 |
| Lund-Johansen, F; Olweus, J | 1 |
| Andersen, LP; Nielsen, H | 1 |
| Smith, DM; Waite, M | 1 |
| Dvorak, AM; Kissell-Rainville, S; Lichtenstein, LM; MacGlashan, DW; Morgan, E; Warner, JA | 1 |
| Kliubin, IV | 1 |
| Blackburn, WD; Chatham, WW; Heck, LW | 1 |
| Curstedt, T; Eklund, A; Forslid, J; Hed, J; Zetterberg, G | 1 |
| Schatz-Munding, M; Ullrich, V | 1 |
| Chen, HC; Fukui, M; Koide, H; Tomino, Y; Watanabe, A; Yaguchi, Y; Yokoyama, K | 1 |
| Berkow, RL | 1 |
| Aitken, RJ; Buckingham, D; Krausz, C; West, K | 1 |
| Bocckino, SB; Murray, JJ; Truett, AP | 1 |
| Liang, B; Petty, HR | 1 |
| Kanaho, Y; Nishida, A; Nozawa, Y | 1 |
| Dahlgren, C; Johansson, A | 2 |
| Alberts, VA; Coffey, RG; Weakland, LL | 1 |
| Kantorski, J; Tchórzewski, H | 1 |
| Chappell, JB; Henderson, LM | 1 |
| Brys, L; de Baetselier, P; Descamps-Latscha, B; Masson, A; Zavala, F | 1 |
| Hruska, KA; Malone, JD; Nishii, Y; Seino, Y; Tanaka, H; Teitelbaum, SL | 1 |
| Ferrante, A; Hardy, SJ; Harvey, DP; Murray, AW; Poulos, A; Robinson, BS | 2 |
| Berger, M; Cowen, DS; Dubyak, GR; Nuttle, L | 1 |
| Haskovec, C; Hrouda, V; Plásek, J; Sigler, K | 1 |
| Klein, JB; McLeish, KR; Scherzer, JA | 1 |
| Kilfeather, SA; O'Malley, K; Stein, M | 1 |
| Burkey, TH; Farmer, JC; Kew, RR; Webster, RO | 1 |
| Edashige, K; Inoue, M; Matsuno, T; Sato, EF; Takahashi, R; Utsumi, K | 1 |
| Saeki, K; Utsumi, K; Yamamoto, M | 1 |
| Oyanagui, Y; Sato, S | 1 |
| Crawford, N; Eggleton, P; Penhallow, J | 1 |
| Bainton, AL; Devalia, V; Faint, R; Linch, DC; Pilkington, GR; Pizzey, A; Roberts, PJ; Thomas, NS | 1 |
| Mohsenin, V; Yoshida, K | 1 |
| Ferro, TJ; Hocking, DC; Johnson, A | 1 |
| Gay, JC; Murray, JJ | 1 |
| Aizawa, S; Itoh, Y; Kuratsuji, T; Ohyashiki, K; Sai, M; Toyama, K | 1 |
| Bellon, G; Borel, JP; Garnotel, R; Monboisse, JC; Perreau, C | 1 |
| Abramson, SB; Kitsis, EA; Weissmann, G | 1 |
| Samuelsson, J | 2 |
| Gordon, LI; Prachand, S; Weiss, D; Weitzman, SA | 1 |
| Schultz, RM | 1 |
| Borgeat, P; Bourgoin, S; Poubelle, PE | 1 |
| Kapp, A; Zeck-Kapp, G | 1 |
| Colucci, M; Conese, M; Fumarulo, R; Giordano, D; Montemurro, P; Riccardi, S; Semeraro, N | 1 |
| Harris, T; Stewart, AG | 1 |
| Lerner, R; Lindström, P; Nilsson, E; Palmblad, J; Patarroyo, M; Rincon, J; Ringertz, B | 1 |
| Ishizuka, T; Kobayashi, S; Kurosawa, M; Nakano, M; Yodoi, J | 1 |
| Berkow, RL; Dodson, RW | 3 |
| Bonak, V; Casnellie, JE; Huang, CK; Laramee, GR | 1 |
| MacGlashan, DW; Warner, JA | 1 |
| Ervens, J; Seifert, R | 1 |
| Elsner, J; Emmendörffer, A; Lohmann-Matthes, M; Roesler, J; Welte, K; Zeidler, C | 1 |
| Erdös, EG; Jackman, HL; Skidgel, RA | 1 |
| Knol, EF; Koenderman, L; Mul, FP; Roos, D; Verhoeven, AJ | 1 |
| Agwu, DE; McCall, CE; McPhail, LC | 1 |
| Lawrence, MB; Springer, TA | 1 |
| Cramer, R; Dri, P; Patriarca, P; Romano, M; Spessotto, P | 1 |
| Forrest, MJ; Jewell, ME; Koo, GC; Sigal, NH | 1 |
| Abraham, RT; Abu-Ghazaleh, RI; Gleich, GJ; Kita, H | 1 |
| Alonso, JL; Campanero, MR; Fresno, M; Pimentel-Muiños, FX; Pivel, JP; Pulido, R; Sánchez-Madrid, F | 1 |
| Croatto, M; Hamilton, JA; Phillips, WA | 1 |
| Didsbury, JR; Gerard, C; Gerard, N; Snyderman, R; Tomhave, E; Uhing, RJ | 1 |
| Bellavite, P; Guzzo, P; Lauciello, C; Negri, M; Zatti, M | 1 |
| Grdisa, M; Vitale, L | 1 |
| Kapp, A; Komann, A; Schöpf, E | 1 |
| Anderson, GP; Hultkvist-Bengtsson, U; Kings, M; Morley, J | 1 |
| Brezinski, ME; Serhan, CN | 1 |
| Allegrezza-Giulietti, A; Beccerica, E; Cervini, C; Ferretti, G; Serretti, R | 1 |
| Basford, RE; Kaplan, SS; Naum, CC | 1 |
| Day, RO; Gebicki, JM; Guille, J; Winn, JS | 1 |
| Baggiolini, M; Delia, D; Garotta, G; Kamber, M; Thelen, M | 1 |
| Bucknall, RC; Edwards, SW; Nurcombe, HL | 1 |
| Andersen, BR; English, D; Zhang, L | 1 |
| Hagenlocker, BE; Walker, BA; Ward, PA | 1 |
| Damerau, B; Gahr, M; Sawatzki, G; Speer, CP | 1 |
| Clay, K; Dale, MM; Twomey, BM | 1 |
| Edwards, SW; Robinson, J; Watson, F | 1 |
| Anderson, R; Myer, MS; Richards, GA; Theron, AJ; van Rensburg, AJ | 1 |
| Graff, I; Schram-Doumont, A; Szpirer, C | 1 |
| Van den Berghe, G; van Waeg, G | 1 |
| Geffner, JR; Isturiz, MA; Lazzari, MA; Schattner, MA | 1 |
| Bonser, RW; Garland, LG; Hodson, HF; Randall, RW; Spacey, GD; Tateson, JE; Thompson, NT | 1 |
| Chiolero, R; Feihl, F; Markert, M; Perret, CH; Schaller, MD; Tagan, MC | 1 |
| Cockcroft, S; Nielson, CP; Stutchfield, J | 1 |
| van Kessel, KP; van Strijp, JA; Verhoef, J | 1 |
| Berg, A; Samuelsson, J | 1 |
| Bultmann, H; Glade, U; Häfker, T; Vicker, MG | 1 |
| Habermehl, GG; Meier, B; Radeke, HH; Resch, K; Selle, S; Sies, H | 1 |
| Creba, J; Pollock, K | 1 |
| Huang, CK; Laramee, GR; Sha'afi, RI; Yamazaki, M | 1 |
| Gay, JC | 2 |
| Ando, M; Araki, S; Fukushima, K; Ito, K; Suga, M | 1 |
| Fagioli, F; Gavioli, R; Giuliani, AL; Lanza, F; Spisani, S; Traniello, S | 1 |
| Abramson, SB; Buyon, JP; Philips, MR; Reibman, J; Slade, SG; Weissmann, G; Winchester, R | 1 |
| Buyon, JP; Merrill, JT; Slade, SG; Weissmann, G; Winchester, R | 1 |
| Nourshargh, S; Williams, TJ | 1 |
| Hanawa, K; Kobayashi, S; Kurosawa, M; Nakano, M | 1 |
| Abboud, CN; Lichtman, MA; Packman, CH; Sham, RL | 1 |
| Bonta, IL; de Jongste, JC; Jongejan, RC; Kerrebijn, KF; Raatgeep, RC | 1 |
| Fedorov, NA; Koshkin, AA; Sud'ina, GF; Tatarintsev, AV; Varfolomeev, SD; Zaitsev, SV | 2 |
| Fontán, PA; Geffner, JR; Isturiz, MA; Sordelli, DO | 1 |
| Delp, C; Madara, JL; Nash, S; Nusrat, A; Parkos, C | 1 |
| Corkey, BE; Disa, S; Fujiki, T; Johnston, RB; Korchak, HM; Majumdar, S; Phillips, WA; Queen, CF; Rosen, OM; Rossi, MW | 1 |
| Greener, M; Hallam, TJ; Merritt, JE; Swayne, GT | 1 |
| Capuozzo, E; Crifò, C; Jullien, S; Salerno, C | 1 |
| Baggiolini, M; Dahinden, CA; Deranleau, DA; Kernen, P; Spry, CJ; Tai, PC; von Tscharner, V; Wymann, MP | 1 |
| Ank, BJ; Roberts, RL; Stiehm, ER | 2 |
| Gay, JC; Stitt, ES | 3 |
| Della Bianca, V; Grzeskowiak, M; Lissandrini, D; Rossi, F | 1 |
| Abramson, JS; Ralston, EP; Wagner, MP; Wei, Y; Wheeler, JG | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| Fletcher, MP; Longhurst, JC; Stahl, GL | 1 |
| Davies, MP; Hallam, TJ; Merritt, JE | 1 |
| Mullane, KM; Sessa, WC | 1 |
| Dahm, LJ; Roth, RA | 1 |
| Collamer, MA; Hartshorn, KL; Tauber, AI; White, MR; Wright, J | 1 |
| Béréziat, G; Cherqui, G; Etienne, J; Kadiri, C; Masliah, J; Rybkine, T | 1 |
| Bowles, CA; Linnekin, D; MacVittie, TJ; Murano, G | 1 |
| Edwards, RJ; MacDermot, J; Storch, J | 1 |
| Ng, D; Parente, J; Prasad, KV; Wong, K | 1 |
| Christiansen, NO | 2 |
| Graeff, RW; Hunt, TK; Mathes, SJ; Paty, PB | 1 |
| Collamer, M; Hartshorn, KL; Schwartz, JH; Tauber, AI; White, MR | 1 |
| Anderson, DC; Dempsey, K; Jones, DH; Krater, SS; Nannen, DD; Schmalstieg, FC; Smith, CW | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Stevens, VL; Winton, EF | 1 |
| Arndt, C; Bruck, ME; Lee, CS; Pike, MC | 1 |
| Solomkin, JS; Tennenberg, SD | 2 |
| Cohen, HJ; Crawford, J; Currie, MS; Jones, A; Padmanabhan, J; Rao, KM | 1 |
| Masuda, Y; Takanaka, K; Taniguchi, K | 1 |
| Caulfield, T; Fiore, S; Kataoka, H; Nicolaou, KC; Serhan, CN | 1 |
| Basford, RE; Clark, RL; Kaplan, SS; Kuhns, DB; Rinaldo, JE; Stiller, RA | 1 |
| Masuda, Y; O'Brien, PJ; Takanaka, K; Taniguchi, K | 1 |
| Clark, RA; Leidal, KG; Nauseef, WM; Volpp, BD | 1 |
| Edashige, K; Inoue, M; Inouye, B; Kobuchi, H; Matsuno, T; Orita, K; Sato, EF; Utsumi, K | 1 |
| Balsinde, J; Mollinedo, F | 1 |
| DiPersio, JF; Gasson, JD; Golde, DW | 1 |
| Becker, W; Borgeat, P; Gyllenhammar, H; Hafström, I; Palmblad, J; Ringertz, B; Svensson, J | 1 |
| Gordon, LI; Lee, SN; Prachard, S; Vasconcelles, MJ; Weitzman, SA | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Aaku, E; Sorsa, T; Wilkström, M | 1 |
| Das, UN; Koratkar, R; Sangeetha, P | 1 |
| Christensen, RH; Lynn, WS; Pratt, PC; Sachs, CW | 1 |
| Dahlgren, C | 3 |
| Gallin, JI; Kleinberg, ME; Leto, T; Malech, HL; Nunoi, H; Rotrosen, D | 1 |
| Abramson, SB; Callegari, PE; Haines, KA; Philips, MR; Reibman, J; Weissmann, G | 1 |
| Anderson, R; Joone, GK; Smit, MJ; Van Staden, AM | 1 |
| Baliga, BS; Dishuck, JF; Mankad, VN; Sindel, LJ | 1 |
| Hartfield, PJ; Robinson, JM | 1 |
| de Haas, M; Huizinga, TW; Kleijer, M; Nuijens, JH; Roos, D; von dem Borne, AE | 1 |
| Tai, HH; Tanizawa, H | 1 |
| Dale, MM; Muid, RE; Twomey, B | 1 |
| Fourel, J; Mattout, C; Mattout, P; Mege, JL; Monnet, V | 1 |
| Gaudry, M; Hakim, J; Marquetty, C | 1 |
| Badwey, JA; Heyworth, PG; Robinson, JM | 1 |
| Bertoli, E; Curatola, G; Fiorini, R; Giorgi, PL; Kantar, A | 1 |
| Curnutte, JT; Mayo, LA | 1 |
| Galilee, CF; Monteiro, HP; Winterbourn, CC | 1 |
| Bonak, VA; Caon, AC; Gaudry, M; Gilbert, C; Huang, CK; McColl, SR; Naccache, PH; Umezawa, K | 1 |
| Huu, TP; Perianin, A; Stanislawski, L | 1 |
| Fletcher, MP; Ziboh, VA | 1 |
| Britigan, BE; Hamill, DR | 1 |
| Cain, DA; Lawson, DL; Mehta, JL; Mehta, P; Nicolini, FA; Schreier, H | 1 |
| Brunton, AH; Edwards, SW; Gadd, GM; Hart, CA; Humphreys, JM; Soulioti, AM; Taylor, CD | 1 |
| Nowak, D | 1 |
| Lambe, BC; Miller, RD; Sahney, NN; Summersgill, JT | 1 |
| Gabler, WL | 1 |
| Carey, F; Forder, RA; Hoult, JR; Moroney, MA | 1 |
| Jaswon, MS; Jones, HM; Khwaja, A; Linch, DC; Roberts, PJ | 1 |
| Bjerrum, OW; Borregaard, N; Nissen, MH | 1 |
| Dinarello, CA; Gelfand, JA; Schindler, R | 1 |
| Bengtsson, T | 1 |
| Giroud, JP; Hakim, J; Perianin, A | 1 |
| Elfman, F; Kelly, E; Lobo, E; Perez, HD | 1 |
| Hartshorn, KL; Karnad, AB; Tauber, AI | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Salamino, F; Sparatore, B | 2 |
| Chambers, TC; Eilon, G; Gallo, MA; Mascardo, RN; Thompson, W | 1 |
| Hasui, M; Hirabayashi, Y; Kobayashi, Y; Komiyama, Y; Masuda, M; Murakami, T; Murata, K | 1 |
| Hallett, MB; Hughes, LE; Williams, JG | 1 |
| Benestad, HB; Hardersen, H; Hersleth, IB; Molvaer, OI | 1 |
| Eher, R; Gadd, SJ; Kasinrerk, W; Knapp, W; Majdic, O; Maurer, D; Stockinger, H | 1 |
| Jalink, K; Moolenaar, WH; van Corven, EJ | 1 |
| Belloc, F; Boisseau, MR; Dumain, P; Freyburger, G; Vincendeau, P | 1 |
| Branzi, A; Caldarera, I; Guarnieri, C; Guizzardi, S; Ligabue, A; Melandri, G; Scheda, M | 1 |
| Aoki, N; Imamura, M; Maruyama, Y; Ohno, Y; Saito, T; Yamaguchi, J; Yamamoto, T | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Coble, BI; Dahlgren, C; Molin, L; Stendahl, O | 1 |
| Bergstrand, H; Lundquist, B; Michelsen, P | 2 |
| Eaton, JW; Greenberg, CS; Skubitz, KM; Vercellotti, GM | 1 |
| Asakawa, M; Hirai, K; Miyamoto, T; Morita, Y; Takaishi, T | 1 |
| Hubbard, W; Lichtenstein, LM; MacGlashan, DW; Miller, PJ; Peters, SP; Stevenson, HC; Warner, JA; Yancey, KB | 1 |
| Jungblut, P; Schultz, G; Seifert, R | 1 |
| Bonak, VA; Casnellie, JE; Gomez-Cambronero, J; Huang, CK; Sha'afi, RI; Shiraishi, T; Wang, E | 1 |
| Agwu, DE; Chabot, MC; Daniel, LW; McCall, CE; McPhail, LC; Wykle, RL | 1 |
| Molski, TF; Sha'afi, RI; Tao, W | 1 |
| Dougherty, RW; Dubay, GR; Niedel, JE | 1 |
| Roberts, RL; Stiehm, ER | 1 |
| Hejny, P; Lam, BK; Ng, CF; Pritchard, KA; Stemerman, MB; Wong, PY | 2 |
| Deierkauf, M; Elferink, JG | 2 |
| Jewell, DP; Mahida, YR; Wu, KC | 1 |
| Foder, B; Scharff, O; Thastrup, O | 1 |
| Kariya, T; Kume, S; Matsumoto, Y; Ozaki, Y; Yatomi, Y | 1 |
| Nath, J; Powledge, A; Wright, DG | 1 |
| Majima, T; Saito, H; Yoshie, O | 1 |
| Burnham, DN; Lambeth, JD; Tyagi, SR; Uhlinger, DJ | 1 |
| Diamond, RD; Kolotila, MP; Ruggeri, R; Smail, EH | 1 |
| Kitagawa, S; Okabe, T; Saito, M; Suzuki, I; Takaku, F; Urabe, A; Yuo, A | 1 |
| Badwey, JA; Heyworth, PG; Karnovsky, ML | 1 |
| Bullock, WW; Creamer, HR; Gabler, WL | 5 |
| Danner, RL; Doerfler, ME; Parrillo, JE; Shelhamer, JH | 1 |
| Edwards, SW; Nurcombe, HL | 1 |
| Anderson, R | 1 |
| Degenhart, HJ; Kerrebijn, KF; Neijens, HJ; Raatgeep, HC | 1 |
| Antman, K; Elias, A; Fredette, JP; Griffin, JD; Schnipper, L; Socinski, M; Sullivan, R | 1 |
| Akabane, T; Komiyama, A; Matsuoka, T; Yamazaki, M; Yasui, K | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Patrone, M; Pontremoli, S; Salamino, F | 1 |
| Budzynski, AZ; Goldsmith, GH; Kazura, JW; Salata, RA; Wenger, JD | 1 |
| Gyllenhammar, H | 2 |
| Becker, EL; Gomez-Cambronero, J; Mege, JL; Molski, TF; Sha'afi, RI | 1 |
| Iizuka, T; Kanegasaki, S; Nakata, M; Tomita, T | 1 |
| Ginsburg, I; Varani, J; Ward, PA | 1 |
| Albertine, KH; Barnett, RB; Gee, MH; Gottlieb, JE; Ishihara, Y; Nguyen, P; Peters, SP; Shusterman, RD | 1 |
| English, D; Hoffman, R; Rizzo, MT; Tricot, G | 1 |
| King, CH; Kusner, DJ | 1 |
| Brown, KE; Derse, CP; Freeland, HS; Peters, SP; Schleimer, RP | 1 |
| Bast, A; Leurs, R; Timmerman, H | 1 |
| Bachelet, M; Béréziat, G; Kadiri, C; Masliah, J; Vargaftig, BB | 1 |
| Thayer, MS; Weisdorf, DJ | 1 |
| Becker, EL; Gomez-Cambronero, J; Mege, JL; Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Hartshorn, KL; Karnad, AB; Myers, JB; Schwartz, JH; Tauber, AI; Wright, J | 1 |
| Bainton, DF; Hibbs, MS | 1 |
| Chi, EY; Goodman, RB; Martin, TR; Matthay, MA; Pistorese, BP | 1 |
| Kalunta, CI; Kaptein, JS; Lad, PM; Lee, GH; Niedzin, H; Scott, SJ | 2 |
| Wada, Y | 1 |
| Badwey, JA; Curnutte, JT; Heyworth, PG; Robinson, JM | 1 |
| el Abbouyi, A; Giroud, JP; Paul, JL; Raichvarg, D; Roch-Arveiller, M; Sarfati, G | 1 |
| Chappell, JB; Henderson, LM; Jones, OT | 1 |
| Baggiolini, M; Dewald, B; Thelen, M; Wymann, MP | 1 |
| Hayashi, K; Imamichi, T; Kaneko, K; Koyama, J; Nakamura, T | 1 |
| Melloni, E; Pontremoli, S | 1 |
| Busse, W; Randlev, B; Sedgwick, J | 1 |
| Arnaout, MA; Chatila, TA; Geha, RS | 1 |
| Blackwell, GJ; Bonser, RW; Dawson, J; Garland, LG | 1 |
| Hallam, TJ; McCarthy, SA; Merritt, JE | 1 |
| Inoue, T; Sendo, F; Takahashi, K; Watanabe, T; Yakuwa, N | 1 |
| Ferrante, A; Goh, DH; Hill, NL; Kumaratilake, L | 1 |
| Symington, FW | 1 |
| Flohé, L; Haurand, M | 1 |
| Briheim, G; Dahlgren, C; Follin, P; Sandstedt, S | 1 |
| Chap, H; Gelas, P; Record, M; Ribbes, G; Terce, F | 1 |
| Berkow, RL; Dodson, RW; Kraft, AS | 2 |
| Baggiolini, M; Deranleau, DA; Kernen, P; Wymann, MP | 1 |
| Damais, C; Frelin, C; Krawice, I; Ladoux, A | 1 |
| Betts, WH; Cleland, LG; Hurst, NP; McColl, SR | 1 |
| Falloon, J; Friedman, MM; Gallin, JI; Nath, J; Ohno, Y; Seligmann, BE | 1 |
| Drury, JK; Hatori, N; Roberts, RL; Stiehm, ER | 1 |
| Bender, JG; Chenoweth, DE; Van Epps, DE | 1 |
| Berkow, RL; Dodson, RW; Howard, TH; Larrick, JW; Wang, D | 1 |
| Arnold, RR; Kinkade, JM; Lambeth, JD; Merrill, AH; Rice, WG; Wilson, E | 1 |
| Gerard, C; McCall, C; Salzer, W | 1 |
| Gavioli, R; Giuliani, A; Spisani, S; Traniello, S | 1 |
| Gomez-Cambronero, J; Huang, CK; Molski, TF; Sha'afi, RI | 1 |
| Kemmerich, B; Pennington, JE | 1 |
| Cunningham, TW; Johnson, KJ; McCulloch, KK; Phan, SH; Powell, J; Ward, PA | 1 |
| Fujie, A; Hamasaki, T; Harada, Y; Sakano, T; Taniguchi, H; Ueda, K | 1 |
| Damiani, G; Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Salamino, F; Sparatore, B | 1 |
| Klempner, MS; Rocklin, RE; Styrt, B | 1 |
| Vissers, MC; Winterbourn, CC | 2 |
| Della Bianca, V; Dusi, S; Grzeskowiak, M; Rossi, F | 2 |
| Baum, H; Shock, A | 1 |
| Lutz, MJ; Till, GO; Ward, PA | 1 |
| Cunningham, TW; Johnson, KJ; McCulloch, KK; Ward, PA | 1 |
| Clay, KL; Guthrie, LA; Johnston, RB; Seccombe, JF; Worthen, GS | 1 |
| Clark, CA; Esposito, AL; Poirier, WJ | 1 |
| Schächtele, C; Seifert, R | 1 |
| Kitagawa, S; Miura, Y; Ohsaka, A; Saito, M; Suzuki, I; Takaku, F | 1 |
| Bonerandi, JJ; Grob, JJ; Mege, JL; Prax, AM | 1 |
| Busse, WW; Gourley, MF; Sedgwick, JB; Vrtis, RF | 1 |
| Lerner, R; Lindström, P; Palmblad, J | 1 |
| König, W; Raulf, M | 1 |
| Baggiolini, M; Thelen, M; Wolf, M | 1 |
| Christiansen, NO; Esmann, V; Juhl, H; Larsen, CS | 1 |
| Grinstein, S; Nasmith, PE | 1 |
| Caon, AC; Faucher, N; McColl, SR; Naccache, PH | 1 |
| Nilsson, E; Palmblad, J | 1 |
| Korchak, HM; Ljubich, P; Rich, AM; Vosshall, LB; Weissmann, G; Zagon, G | 1 |
| Bathurst, IC; Brennan, SO; George, PM; Vissers, MC; Winterbourn, CC | 1 |
| Hyers, TM; McGarrity, ST; Webster, RO | 1 |
| Brom, J; König, W; Schönfeld, W | 1 |
| Andre, P; Benoliel, AM; Bongrand, P; Capo, C; Mege, JL; Pouget, J; Serratrice, G | 1 |
| Ellis, JA; Jones, OT; Mayer, SJ | 1 |
| Burnham, DN; Lambeth, JD; Tamura, M; Tyagi, SR | 1 |
| Christiansen, NO; Esmann, V; Larsen, CS | 1 |
| Fredette, JP; Griffin, JD; Horne, JH; Lazzari, KG; Leavitt, JL; Lyman, CA; Melnick, DA; Simons, ER; Sullivan, R; Wright, J | 1 |
| Baggiolini, M; Dewald, B; Thelen, M | 1 |
| Berkow, RL; Dodson, MR | 1 |
| Bailly, S; Pasquier, C; Rebut-Bonneton, C | 1 |
| Hyers, TM; McGarrity, ST; Stephenson, AH; Webster, RO | 1 |
| Holman, RG; Maier, RV | 1 |
| Cowen, DS; Dubyak, GR; Meuller, LM | 1 |
| Di Perri, T; Pasini, FL | 1 |
| Hewett, JA; Roth, RA | 1 |
| Fóris, G; Fülöp, T; Nagy, JT; Varga, Z | 1 |
| Hirakawa, M; Okimasu, E; Tsuchiya, M; Ueda, W; Utsumi, K | 1 |
| Justen, JM; Sam, LM; Smith, RJ | 1 |
| Boeynaems, JM; Flament, J; Schandene, L | 1 |
| Cotter, TG; Meagher, LC | 1 |
| Oliver, CN | 1 |
| Benetti, D; Brunelleschi, S; Fantozzi, R; Mian, M; Rubino, A; Tarli, S; Zilletti, L | 1 |
| Perianin, A; Synderman, R | 1 |
| MacIntyre, DE; Meurer, R | 1 |
| Cohn, ZA; Detmers, PA; Kimball, B; Olsen, E; Wright, SD | 1 |
| Bellavite, P; De Togni, P; Della Bianca, V; Grzeskowiak, M; Rossi, F | 1 |
| Berube, ML; Sedgwick, JB; Zurier, RB | 1 |
| Barrowman, MM; Cockcroft, S; Gomperts, BD | 2 |
| Dale, MM; Penfield, A | 1 |
| Borgeat, P; Molski, TF; Naccache, PH; Sha'afi, RI; White, JR | 1 |
| Gallin, JI; Ohno, Y; Seligmann, BE | 1 |
| Becker, EL; Feinstein, MB; Molski, TF; Munoz, JJ; Naccache, PH; Sha'afi, RI; Shefcyk, J; Volpi, M; Yassin, R | 1 |
| Bender, JG; Van Epps, DE | 1 |
| Gennaro, DE; Hoffstein, ST; Manzi, RM | 2 |
| Cassatella, M; De Togni, P; Della Bianca, V; Grzeskowiak, M; Rossi, F | 1 |
| Cochrane, CG; Jesaitis, AJ; Parkos, CA; Schmitt, M | 1 |
| Homma, Y; Ishitoya, J; Kato, M; Nagai, Y; Takenawa, T | 1 |
| Feinstein, MB; Molski, TF; Naccache, PH; Sha'afi, RI; Shefcyk, J; Tao, W; Volpi, M; White, JR; Yassin, R | 1 |
| Becker, EL; Molski, MM; Naccache, PH; Sha'afi, RI; Volpi, M | 1 |
| Ishibashi, S; Kawanishi, M; Ohtsuka, T; Okamura, N; Uchida, M | 1 |
| Borinski, R; Ginsburg, I; Pabst, M | 1 |
| Hara, E; Someya, A; Yamashita, T | 1 |
| Bender, JG; Chenoweth, DE; Steinkamp, JA; Van Epps, DE | 1 |
| Baggiolini, M; Catanese, B; Mauderli, P; Näf, U | 1 |
| Bose, SK; Grisham, MB; Jones, HP; McCord, JM; Schott, A; Shannon, VA | 1 |
| Ohta, H; Okajima, F; Ui, M | 1 |
| Haimes, CS; Kazura, JW; King, CH; Mahmoud, AA; Olds, GR; Peck, CA; Sawyer, JA; Spagnuolo, PJ | 1 |
| Klempner, MS; Styrt, B | 1 |
| Bass, DA; Gerard, C; Marfat, A; McCall, CE; McPhail, LC; Stimler-Gerard, NP | 1 |
| Jakoi, L; McPhail, LC; Pike, MC; Snyderman, R | 1 |
| Beckman, JK; Gay, JC; Lukens, JN; Zaboy, KA | 1 |
| Becker, EL; Feinstein, MB; Kanaho, Y; Matsumoto, T; Molski, TF; Naccache, PH; Pelz, C; Sha'afi, RI; Volpi, M | 1 |
| Cassatella, MA; Della Bianca, V; Grzeskowiak, M; Rossi, F; Zeni, L | 1 |
| Cassatella, MA; Della Bianca, V; Grzeskowiak, M; Rossi, F | 1 |
| Breitman, TR; Imaizumi, M | 1 |
| Connolly, NL; Senior, RM; Welgus, HG | 1 |
| Hamamori, Y; Kaibuchi, K; Kikuchi, A; Kozawa, O; Takai, Y | 1 |
| Hayashi, S; Ichinose, Y; Itoh, T; Kaku, M; Nakanishi, M; Shigematsu, N; Tomoda, A; Yagawa, K; Yoneyama, Y | 1 |
| Benoliel, AM; Bongrand, P; Capo, C; Mege, JL | 1 |
| Huang, CK; Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Sacco, O; Salamino, F; Sparatore, B | 3 |
| Bale, JF; Clark, RA; De Alarcon, P; Nauseef, WM | 1 |
| Gee, JB; Ingbar, DH; Lwebuga-Mukasa, JS; Merrill, WW; Polomski, L; Sibille, Y | 1 |
| Ford, C; Molski, TF; Sha'afi, RI; Weisman, SJ | 1 |
| Minta, JO; Williams, MD | 1 |
| Baricordi, RO; Damiani, G; Dovigo, L; Gavioli, R; Sensi, A; Spisani, S; Traniello, S | 1 |
| Aviram, I; Sharabani, M | 1 |
| Davis, P; Parente, JE; Wong, K | 1 |
| Bell, RM; Lambeth, JD; Merrill, AH; Olcott, MC; Wilson, E | 1 |
| Bell, AL; Betts, WH; Cleland, LG; French, JK; Hurst, NP; Nuki, G; O'Donnell, ML | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Anast, C; Arceci, R; Beard, CJ; Ezekowitz, RA; Key, L; Miller, B; Newburger, PE; Proto, P; Ryan, T; Simons, ER | 1 |
| Mandell, GL; Wright, GG | 1 |
| Korchak, HM; Rich, AM; Roberts, C; Vienne, K; Weissmann, G; Wilkenfeld, C | 1 |
| Gillespie, MN; Jay, M; Kojima, S | 1 |
| Fujita, I; Minakami, S; Takeshige, K | 1 |
| Furuya, W; Grinstein, S | 1 |
| Gasson, JC; Golde, DW; Kwan, L; Weisbart, RH | 1 |
| Cronstein, BN; Hirschhorn, R; Kubersky, SM; Weissmann, G | 1 |
| Ford, C; Punzo, A; Sha'afi, RI; Weisman, SJ | 1 |
| Hoffman, MD; Wright, CD | 1 |
| Giedd, KN; Haines, KA; Korchak, HM; Rich, AM; Weissmann, G | 1 |
| Becker, EL; Kanaho, Y; Matsumoto, T; Molski, TF; Sha'afi, RI | 1 |
| Smith, CD; Snyderman, R; Uhing, RJ | 1 |
| Nielsen, H; Valerius, NH | 1 |
| Ishitoya, J; Takenawa, T; Yamakawa, A | 1 |
| Blackburn, WD; Heck, LW; Wallace, RW | 1 |
| Leonard, EJ; Shenai, A; Skeel, A | 1 |
| Gabler, WL; Harold, W; Roberts, D | 1 |
| Molski, TF; Sha'afi, RI | 1 |
| Jesaitis, AJ; Omann, GM; Tolley, JO | 1 |
| Gillespie, MN; Jay, M; Kojima, S; Owasoyo, JO | 1 |
| Miyahara, M; Okimasu, E; Utsumi, K; Watanabe, S | 1 |
| Ashworth, RF; Cook, RM; Musgrove, NR | 1 |
| Bitter-Suermann, D; Englberger, W; Hadding, U | 1 |
| Ishibashi, S; Ohtsuka, T; Okamoto, T; Okamura, N; Ozawa, M; Uchida, M | 1 |
| Hunt, DA; Katona, IM; McCartney-Francis, N; Smith, PD; Wahl, LM; Wahl, SM | 1 |
| Ando, M; Araki, S; Nakashima, H; Soda, K; Suga, M; Sugimoto, M | 1 |
| Caldarera, I; Flamigni, F; Georgountzos, A; Guarnieri, C; Ligabue, A | 1 |
| Aso, H; Hayashi, S; Ichinose, Y; Maruyama, M; Nakanishi, M; Ogata, K; Shigematsu, N; Yagawa, K | 1 |
| Baggiolini, M; Deranleau, DA; von Tscharner, V; Wymann, MP | 1 |
| Andersson, T; Dahlgren, C; Stendahl, O | 1 |
| Babior, BM | 1 |
| Kitagawa, S; Ohsaka, A; Saito, M; Takaku, F; Yuo, A | 1 |
| Becker, EL; Feinstein, MB; Molski, TF; Naccache, PH; Sha'afi, RI; Shefcyk, J; Volpi, M; White, JR; Yassin, R | 1 |
| Berton, G; Cassatella, MA; Rossi, F; Zeni, L | 1 |
| Lands, WE; Marshall, PJ | 1 |
| Hall, ND; Maslen, C; Stevens, TR | 1 |
| Howard, TH; Wang, D | 1 |
| Ho, YS; Lee, WM; Snyderman, R | 1 |
| Lackie, JM; Lawrence, AJ | 1 |
| Pincus, SH; Ramesh, KS; Rocklin, RE | 1 |
| Fritsch, H; Müller-Peddinghaus, R; Wurl, M | 1 |
| Gallin, JI; Seligmann, BE; Zimmerli, W | 1 |
| Elferink, JG | 1 |
| Arnaout, MA; Freyer, DR; Morganroth, ML; Rogers, CE; Todd, RF | 1 |
| Matsumoto, T; Sha'afi, RI; Tao, W | 1 |
| Hickman, J; Hughes, L; Thompson, M | 1 |
| Bochner, BS; Brown, KE; Peachell, PT; Schleimer, RP | 1 |
| Akizuki, S; Higuchi, Y; Setoguchi, M; Yamamoto, S; Yoshida, S | 1 |
| Lambeth, JD; Liotta, DC; Merrill, AH; Mullins, RE; Uhlinger, DJ; Wang, E; Wilson, E | 1 |
| Gliemann, J; Okuno, Y | 1 |
| Maclouf, J; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Maclouf, J; Pelé, JP; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Christensen, SB; Fujiki, H; Hirasawa, N; Ohuchi, K; Sugawara, T; Sugimura, T; Tsurufuji, S; Watanabe, M | 1 |
| Christopher, B; Dormandy, JA; Jones, JG; Mikita, J; Nash, GB | 1 |
| Changelian, PS; Collins, LA; Fearon, DT; Jack, RM | 1 |
| Becker, EL; Huang, CK; Marsh, ML; Molski, TF; Munoz, J; Naccache, PH; Sha'afi, RI; Shefcyk, J; Volpi, M | 1 |
| Dahlgren, C; Lock, R | 1 |
| Oser, A; Rothe, G; Valet, G | 1 |
| Hashimoto, T; Hosaka, S; Masuko, S; Shimizu, A; Takeuchi, A; Uchida, T | 1 |
| Ferrante, A; McCormack, JG; Seow, WK; Thong, YH | 1 |
| Giroud, JP; Gougerot-Pocidalo, MA; Hakim, J; Perianin, A | 1 |
| Babin-Chevaye, C; Hakim, J; Labro, M; Pochet, I | 1 |
| Bozeman, PM; Hoidal, JR; Shepherd, VL | 1 |
| Roos, D; van Schaik, ML; Verhoeven, AJ; Weening, RS | 1 |
| Kramer, IM; Roos, D; van der Bend, RL; Verhoeven, AJ; Weening, RS | 1 |
| Casnellie, JE; Huang, CK; Laramee, GR | 1 |
| Babior, BM; Curnutte, JT; Okamura, N; Roberts, RL | 1 |
| Benestad, HB; Opdahl, H; Ruud, B | 1 |
| Davis, BH; Langweiler, M | 1 |
| Lindeyer, E; Raghoebar, M; Van den Berg, WB; Van Ginneken, CA | 1 |
| Miyahara, M; Okimasu, E; Sato, F; Uchida, H; Utsumi, K; Yamamoto, M | 1 |
| Campbell, AK; Hallett, MB; Patel, AK | 1 |
| Keller, HU; Roos, FJ; Zimmermann, A | 1 |
| Ikeda, K; Kikuchi, A; Kozawa, O; Takai, Y | 1 |
| Changelian, PS; Fearon, DT | 1 |
| Gadenne, AS; Griffin, JD; Lazzari, KG; Leavitt, JL; Malech, HL; Melnick, DA; Meshulam, T; Proto, PJ; Simons, ER; Sullivan, R | 1 |
| Ferrante, A; Seow, WK; Thong, YH | 1 |
| Breitman, TR; Hemmi, H; Imaizumi, M | 1 |
| Andersson, T; Dahlgren, C; Lew, PD; Stendahl, O | 1 |
| McCormack, JG; Seow, WK; Smith, SE; Thong, YH | 1 |
| Bass, DA; Gerard, C; McCall, CE; McPhail, LC; Olbrantz, P; Wilson, J | 1 |
| Benestad, HB; Nicolaysen, G; Opdahl, H | 1 |
| Baehner, RL; Baker, MD; Lafuze, JE; Oakes, AL | 1 |
| Fletcher, MP | 1 |
| English, D; Gabig, TG | 1 |
| Grewal, IS; Lad, PM; Olson, CV | 1 |
| Rao, KM | 1 |
| Andersson, T; Bengtsson, T; Stendahl, O | 1 |
| Fletcher, MP; Seligmann, BE | 1 |
| Andersson, T; Krause, KH; Lew, PD; Schlegel, W; Waldvogel, FA; Wollheim, CB | 1 |
| Henderson, WR; Klebanoff, SJ; Neill, MA | 1 |
| Bass, DA; Parce, JW; Seeds, MC; Szejda, P | 1 |
| Smith, RJ; Speziale, SC | 1 |
| Feltner, DE; Marasco, WA; Varani, J; Ward, PA | 1 |
| Hoult, JR; Nourshargh, S | 1 |
| Cooke, E; Hallett, MB | 1 |
| Johnson, KJ; Sulavik, MC; Ward, PA | 1 |
| McPhail, LC; Snyderman, R | 2 |
| Gallin, JI; Seligmann, BE | 1 |
| Snyderman, R | 1 |
| Thomson, DM | 1 |
| Marangoni, C; Spisani, S; Traniello, S | 1 |
| Cavalletti, T; Gavioli, R; Marangoni, C; Spisani, S; Traniello, S | 1 |
| Andrews, PC; Babior, BM | 2 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G | 1 |
| Borgeat, P; Molski, TF; Naccache, PH; Sha'afi, RI | 1 |
| Guthrie, LA; Henson, PM; Johnston, RB; McPhail, LC | 1 |
| Gervais, F; Mraz, C; Skamene, E; Somerfield, SD; Stach, JL | 1 |
| Takanaka, K; Taniguchi, K | 1 |
| Baehner, RL; Boxer, LA; Parmley, RT; Tzeng, DY | 1 |
| Aida, N; Miyamoto, T; Morita, Y | 1 |
| Kudo, K; Miyamoto, T; Morita, Y; Takaishi, T | 1 |
| Castranova, V; Jones, GS; VanDyke, K | 1 |
| Henson, PM; Johnston, RB; McPhail, LC | 1 |
| English, D; Lukens, JN; Roloff, JS | 1 |
| Lees, CJ; McCall, CE; O'Flaherty, JT; Shewmake, T; Thomas, MJ; Wykle, RL | 1 |
| Cole, PJ; Williams, AJ | 2 |
| Fletcher, MP; Gallin, JI; Seligmann, BE | 1 |
| Hammett, MJ; Love, SH; McCall, CE; O'Flaherty, JT; Shewmake, TB; Thomas, MJ; Wykle, RL | 1 |
| August, JT; Skubitz, KM; Zhen, YS | 1 |
| Clark, RA; Szot, S | 1 |
| Edelson, HS; Kaplan, HB; Korchak, HM; Smolen, JE; Weissmann, G | 1 |
| Dahlgren, C; Magnusson, KE; Stendahl, O; Sundqvist, T | 1 |
| Charon, J; Mizel, D; Pick, E | 1 |
| Johnston, RB; McPhail, LC; Musson, RA; Shafran, H | 1 |
| Smolen, JE; Weissmann, G | 1 |
| Baggiolini, M; Bretz, U; Dewald, B | 2 |
| Alteri, E; Harvath, L; Lazdins, JK; Leonard, EJ | 1 |
| English, D; Lukens, JN | 1 |
| Dahlgren, C; Stendahl, O | 2 |
| Bonvini, E; Bougnoux, P; Hoffman, T; Markey, S; Stevenson, HC; Zatz, M | 1 |
| Bender, JG; McPhail, LC; Van Epps, DE | 1 |
| Broekman, MJ; Korchak, HM; Marcus, AJ; Serhan, CN; Smolen, JE; Weissmann, G | 1 |
| Fantone, JC; Kinnes, DA | 1 |
| Fletcher, MP; Gallin, JI | 1 |
| Cotton, DJ; Gallin, JI; O'Brien, WF; Seligmann, B | 1 |
| English, D; Janco, RL | 1 |
| Costello, MJ; Gewurz, H; Siegel, JN | 1 |
| Coble, BI; Dahlgren, C; Hed, J; Molin, L; Stendahl, O | 1 |
| Minakami, S; Sumimoto, H; Takeshige, K | 1 |
| Aviram, I; Babior, BM; Simons, ER | 1 |
| Test, ST; Weiss, SJ | 1 |
| Korchak, HM; Rutherford, LE; Weissmann, G | 1 |
| Chew, C; Wong, K | 1 |
| Elgas, LJ; Fantone, JC; Marasco, WA; Ward, PA | 1 |
| Borinski, R; Christensen, P; Eliasson, I; Ginsburg, I; Lahav, M; Malamud, D; Matzner, Y | 1 |
| Bonvini, E; Bougnoux, P; Hoffman, T; Miller, P; Stevenson, HC | 1 |
| Friedman, MM; Gallin, JI; Metcalf, JA; Roos, D; Seligmann, B | 1 |
| Briheim, G; Dahlgren, C; Stendahl, O | 1 |
| Duque, RE; Fantone, JC; Phan, SH | 1 |
| Abramson, S; Edelson, HS; Given, WP; Kaplan, HB; Korchak, HM; Weissmann, G | 1 |
| Clayton, CC; McPhail, LC; Snyderman, R | 1 |
| Becker, EL; Hill, JM; Huang, CK; Naccache, PH; Sha'afi, RI; White, JR | 1 |
| Austen, KF; Ringel, EW; Soter, NA | 1 |
| McCall, CE; O'Flaherty, JT; Schmitt, JD; Wykle, RL | 1 |
| Schell-Frederick, E | 1 |
| Ballestrero, A; Dallegri, F; Frumento, G; Patrone, F; Sacchetti, C | 1 |
| Borisy, GG; Pryzwansky, KB; Schliwa, M | 1 |
| Keisari, Y; Pick, E | 1 |
| Broekman, MJ; Korchak, HM; Marcus, AJ; Serhan, CN; Weissmann, G | 1 |
| Dean, RT; Leoni, P | 1 |
| Allen, J; Baehner, RL; Boxer, LA; Oseas, RS; Yang, HH | 1 |
| Bowman, BJ; Smith, RJ | 1 |
| Abramson, JS; Bass, DA; Heller, KA; Lyles, DS | 1 |
| Eisenstat, BA; Smolen, JE; Weissmann, G | 1 |
| Varani, J | 1 |
| Baehner, RL; Boxer, LA; Oseas, R; Yang, HH | 1 |
| Romeo, D; Schneider, C; Zanetti, M | 1 |
| Chused, TM; Gallin, JI; Seligmann, B | 1 |
| Káldi, K; Kapus, A; Ligeti, E; Suszták, K | 1 |
| Andersson, T; Löfgren, R; Ng-Sikorski, J; Sjölander, A | 1 |
| Casolaro, V; de Paulis, A; Guidi, G; Marino, O; Marone, G; Meliota, S; Patella, V | 1 |
| Bochner, BS; MacGlashan, DW; Warner, JA | 1 |
| Amon, U; von Stebut, E; Wolff, HH | 1 |
| Buschauer, A; Czarnetzki, B; Frank, G; Josties, C; Kleine-Tebbe, J; Kunkel, G; Schunack, W; Stalleicken, D | 1 |
| Bochner, BS; Galli, SJ; Guo, CB; Kagey-Sobotka, A; Lichtenstein, LM; Liu, MC | 1 |
| Parent, D; Remold-O'Donnell, E | 1 |
| Ingraham, RH; Kahn, J; Kishimoto, TK; Migaki, GI; Shirley, F | 1 |
| Buyon, JP; Merrill, JT; Winchester, RJ | 1 |
| Musgrave, IF; Schultz, G; Seifert, R | 1 |
| Berton, G; Fumagalli, L; Laudanna, C; Sorio, C | 1 |
| Avalos, BR; Bartynski, KJ; Burton, WG; Elder, PJ; Kotur, MS; Wilkie, NM | 1 |
| Hirai, K; Iida, M; Ito, K; Morita, Y; Sakamoto, Y; Shinohara, S; Takaishi, T; Yamaguchi, M | 1 |
| Adams, DH; Burnett, D; Grant, RA; Liu, Q; Lord, JM; Martin, TJ; Stockley, RA | 1 |
| Amon, U; Herbert, JM; von Stebut, E; Wolff, HH | 1 |
| Garcia-Welsh, A; Laskin, DL; Laskin, JD; Molloy, CJ | 1 |
| Gon, S; Murata, K; Sendo, F; Watanabe, T; Yamashita, T | 1 |
| Bodlaj, R; Glaubitt, SI; Hübner, C; Krombach, F; Lehr, HA; Messmer, K; Münzing, S; Seiffge, D; von Andrian, UH | 1 |
| Leung, CC; Raffin, TA; Schumann, MA | 1 |
| Ingraham, R; Kahn, J; Kishimoto, TK; Mainolfi, E; Migaki, G; Rothlein, R; Shirley, F | 1 |
| Collins, PW; Gutteridge, CN; Kelsey, SM; Newland, AC; Williams, MA | 1 |
| Andersen, PL; Laursen, AL; Rungby, J | 1 |
| MacGlashan, DW | 1 |
| Bourgoin, S; Houle, MG; Kahn, RA; Naccache, PH | 1 |
| Ahmed, MU; Hazeki, K; Hazeki, O; Katada, T; Ui, M | 1 |
| Edashige, K; Mamiya, K; Manabe, M; Tomoda, MK; Ueda, W | 1 |
| Kobuchi, H; Nojima, S; Saibara, T; Utsumi, K; Yasuda, T | 1 |
| Ahmed, K; Campbell, KD; Skubitz, AP; Skubitz, KM | 1 |
| Cervini, C; Core, P; Grassi, W; Muti, S; Serretti, R | 1 |
| Bleasdale, JE; Justen, JM; Sly, LM; Smith, RJ | 1 |
| Eiznhamer, D; Fields, JZ; Kazi, N; Keshavarzian, A; Kottapalli, V; Sedghi, S; Winship, D | 1 |
| Bokoch, GM; Chernoff, J; Dong, HJ; Knaus, UG; Morris, S | 1 |
| Heiskanen, KM; Naarala, J; Savolainen, KM | 1 |
| Naarala, J; Ruotsalainen, M; Savolainen, KM | 1 |
| Dang, PM; Hakim, J; Périanin, A; Rais, S | 1 |
| Jacquier-Sarlin, MR; Kantengwa, S; Maridonneau-Parini, I; Polla, BS; Stubbe, H | 1 |
| Costa Rosa, LF; Curi, R; Murphy, C; Newsholme, P | 1 |
| Comhaire, F; Hafez, T; Mahmoud, A; Zalata, A | 1 |
| Abe, M; Furuno, T; Hara, N; Hidaka, K; Mitsuyama, T; Takeshige, K; Tanaka, T | 1 |
| Filep, JG; Földes-Filep, E; Fournier, A | 1 |
| Edwards, SW; Stringer, RE | 1 |
| Azzarà, A; Bruschi, F; Carulli, G; Minnucci, S | 1 |
| Diamond, MS; Springer, TA | 1 |
| Bratton, DL | 1 |
| Bambara, LM; Bellavite, P; Biasi, D; Caraffi, M; Carletto, A; Chirumbolo, S; Serra, MC | 1 |
| Bazil, V; Strominger, JL | 1 |
| Katsura, Y; Kayashima, S; Noritake, M; Rokutanda, M; Shinomiya, M; Shinomiya, N; Tsuru, S; Wakiyama, H | 1 |
| Duncker, HP; Koch, T; Möschet, B; Neuhof, H; Schönharting, M; Stein, A; van Ackern, K | 1 |
| Kobuchi, H; Kurashige, T; Minakami, K; Miyahara, M; Utsumi, K; Watanabe, Y | 1 |
| Asai, T; Itoh, K; Oh, H; Wakita, H; Yoshida, S | 1 |
| Knol, EF; Kuijpers, TW; Mul, FP; Roos, D | 1 |
| Badwey, JA; Ding, J; Gilbert, BA; Lim, YH; Rando, RR | 1 |
| Augustinsson, A; Elwing, H; Lassen, B; Nimeri, G; Ohman, L; Stendahl, O | 1 |
| Forslund, T; Sundqvist, T | 2 |
| Hartshorn, KL; Kazhdan, MM; Liou, LS; Tauber, AI; Tauber, JL; White, MR | 1 |
| Bellido, L; López-González, MA; Lucas, M; Pedrera, C | 1 |
| Turner, NC; Wood, LJ | 1 |
| Watts, RG | 2 |
| Combadière, C; Djerdjouri, B; Hakim, J; Pedruzzi, E; Périanin, A | 1 |
| Johnston, RB; Kawai, K; Kutsumi, H; Rokutan, K | 1 |
| Feoktistov, A; Philips, MR; Pillinger, MH; Weissmann, G | 1 |
| Bratt, J; Lerner, R; Palmblad, J; Ringertz, B | 1 |
| Chiara, MD; Conde, M; Pintado, E; Sobrino, F | 1 |
| Abramson, SB; Feoktistov, A; Philips, MR; Pillinger, MH | 1 |
| Badwey, JA; Brown, RF; Ding, J; Liu, R; Vlahos, CJ | 1 |
| Roney, PL | 1 |
| Colotta, F; Fadlon, EJ; Mantovani, A; Matteucci, C; Orlando, S; Sozzani, S | 1 |
| Ruotsalainen, M; Savolainen, KM | 2 |
| Chap, H; Planat, V; Record, M; Ribbes, G; Tercé, F; Tronchère, H | 1 |
| Antonaci, S; Jirillo, E; Polignano, A; Tortorella, C; Venezia, A | 1 |
| Jove, R; Nairn, R; Suchard, SJ; Yu, H | 1 |
| Baldi, G; Bevilacqua, M; Dallegri, F; Norbiato, G; Renesto, E; Vago, T | 1 |
| Bonneau, C; Couderc, R; Giroud, JP; Raichvarg, D; Roch-Arveiller, M | 1 |
| al-Essa, LY; Kobayashi, M; Kohno, K; Niwa, M; Nozaki, M; Tsurumi, K | 1 |
| Benhaim, P; Benz, CC; Hunt, TK; Mathes, SJ; Scheuenstuhl, H | 1 |
| Anderson, R; Steenkamp, KJ; Theron, AJ | 1 |
| Fuji, H; Goshima, K; Hori, M; Hoshida, S; Kamada, T; Kuzuya, T; Nishida, M; Tada, M | 1 |
| Jaswon, MS; Jones, HM; Linch, DC | 1 |
| Bangalore, N; Travis, J | 1 |
| Katz, A; Levy, R; Riesenberg, K; Schlaeffer, F | 1 |
| Jakabovics, E; Kane, LH; Kilpatrick, LE; Korchak, HM; McCawley, LJ | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Christensen, MM; Hansen, B; Nielsen, SL; Obel, N; Rungby, J | 1 |
| Chinnaiyan, AM; Desrochers, PE; Gibbs, DF; Johnson, KJ; Mulligan, MS; Varani, J; Weiss, SJ | 1 |
| Andrioli, G; Bellavite, P; Bonazzi, L; Chirumbolo, S; Ferro, I; Lippi, G | 1 |
| Volz, A | 1 |
| Allen, PG; Brady, HR; Janmey, PA; Matsubara, M; Serhan, CN; Takata, S | 1 |
| Jack, RM; Lowenstein, BA; Nicholson-Weller, A | 1 |
| Akard, L; Cui, Y; English, D; Harvey, K; Hughes, CV; Jansen, J; Neel, S; Siddiqui, R | 1 |
| Dang, Y; Edwards, SW; Galvani, DW; Lowe, GM; Watson, F | 1 |
| Dikshit, M; Kumari, R; Seth, P; Srimal, RC | 1 |
| Johnston, RB; Moriguchi, T; Ravichandran, V; Seres, T; Thomas, JA | 1 |
| Daniels, RH; Elmore, MA; Finnen, MJ; Hill, ME; Lackie, JM; Shimizu, Y | 1 |
| Blackburn, WD; Chatham, WW; Turkiewicz, A | 1 |
| MacLarkey, WR; Orr, FW; Shaughnessy, SG; Soares, FA | 1 |
| Akopov, SE; Sercombe, R; Seylaz, J | 1 |
| Ando, M; Mori, T; Takagi, K | 1 |
| Koshida, H; Kotake, Y; Reinke, LA; Tanigawa, T | 1 |
| Corkey, BE; Kane, LH; Korchak, HM; Rossi, MW | 1 |
| Forslid, J; Hed, J; Palmblad, J; Samuelsson, J | 1 |
| Buch, JP; Das, DK; Kolon, TF; Kreutzer, DL; Maulik, N | 1 |
| Rothe, G; Valet, G | 1 |
| Edwards, SW; Martin, JH | 2 |
| Davies, EV; Hallett, MB; Harding, KG; Lane, IF; Whiston, RJ | 1 |
| Nagase, M; Nishiya, H; Noda, M | 1 |
| Chuchalin, AG; Kuchkina, NV; Orlov, SN; Pokudin, NI | 2 |
| Klegeris, A; McGeer, PL | 1 |
| Fujiwara, T; Hattori, K; Hirata, Y; Kobayashi, Y; Kojima, T | 1 |
| Antosiewicz, J; Bertoli, E; Fiorini, R; Kantar, A; Tanfani, F; Tartaglini, E; Wozniak, M | 1 |
| Aitken, RJ; Krausz, C; Mills, C; Rogers, S; Tan, SL | 1 |
| Coburn, JP; Eggleton, P; Ghebrehiwet, B; Sastry, KN; Tauber, AI; Zaner, KS | 1 |
| Franson, RC; Rosenthal, MD | 1 |
| Charalambous, K; de las Heras, B; Hoult, JR | 1 |
| Babior, BM; el Benna, J; Faust, LP | 1 |
| Akerman, KE; Leino, L; Tuominen, H | 1 |
| Berton, G; Laudanna, C; Rossi, F | 1 |
| Egesten, A; Gullberg, U; Olsson, I; Richter, J | 1 |
| Halbwachs-Mecarelli, L; Lesavre, P; Rieu, P | 1 |
| Ahnfelt-Rønne, I; Berild, D; Bouchelouche, PN; Nielsen, OH | 1 |
| Narayanan, R; Rosen, CA; Sartorelli, AC; Sokoloski, JA | 1 |
| Koshida, H; Kotake, Y | 1 |
| Javors, MA; Olson, MS; Zhou, W | 1 |
| Gacon, G; Le Cabec, V; Maridonneau-Parini, I; Möhn, H | 1 |
| Denison, M; Ganey, PE; Robinson, JP; Roth, RA; Sirois, JE | 1 |
| Jacobs, AA; Lederer, ED; McLeish, KR | 1 |
| Abdelghaffar, H; Charlier, N; el Benna, J; Hakim, J; Labro, MT | 1 |
| Connelly, PA; Farrell, CA; Richard, S; Shaw, AS; Showell, HJ | 1 |
| Baker, L; Cutilli, JR; Douglas, SD; Kilpatrick, L; Korchak, HM; McCawley, LJ; Stanley, CA | 1 |
| De la Fuente, M; Del Rio, M | 1 |
| Hansen, B; Obel, N; Storgaard, M; Zachariae, H | 1 |
| Abo, A; Grogan, A; Segal, AW; Webb, MR | 1 |
| Marshall, CJ; Saklatvala, J; Thompson, HL | 1 |
| Coleman, H; Huang, CK; Liang, L; Stevens, T | 1 |
| Cave, CM; Solomkin, JS; Tindal, CJ; Zemlan, F | 1 |
| Osaki, T; Ueta, E; Umazume, M; Yamamoto, T | 1 |
| Edashige, K; Kawada, M; Utsumi, K; Watanabe, Y; Yasuda, T | 1 |
| Levy, R; Liel, Y; Nagauker-Shriker, O; Rudich, A; Yermiyahu, T | 1 |
| Goode, HF; Howdle, PD; Walker, BE; Webster, NR | 1 |
| Davis, SA; Goldwater, D; Klein, JB; Koebel, DA; McLeish, KR; Miller, ES; Sonnenfeld, G | 1 |
| Schächtele, C; Seifert, R; Wenzel-Seifert, K | 1 |
| Figala, V; Schmid, E; Ullrich, V | 1 |
| Endoh, M; Kashem, A; Nakazawa, H; Nomoto, Y; Sakai, H | 1 |
| Iwata, M; Miyahara, M; Nishihara, Y; Saeki, K; Watanabe, Y | 1 |
| Badwey, JA; Ding, J; Gilbert, BA; Lu, DJ; Ma, YT; Maddox, JF; Pérez-Sala, D; Rando, RR | 1 |
| Hurttia, HM; Leino, L; Sewon, LA; Sorvajärvi, K | 1 |
| Fukumitsu, T; Haraoka, M; Kubo, S; Kumazawa, J; Matsumoto, T; Mihara, Y; Takahashi, K; Takayama, K; Tanaka, M; Yoshimine, K | 1 |
| Ishibashi, S; Kuwana, M; Okamura, N; Sakai, M; Sasaki, J; Yamaguchi, M | 1 |
| Crastes de Paulet, A; Damon, M; Dore, JC; le Doucen, C; Limasset, B; Ojasoo, T | 1 |
| Azuma, EK; Kitagawa, S; Mizoguchi, H; Saito, M; Takaku, F; Umezawa, K; Yuo, A | 1 |
| Combadière, C; el Benna, J; Hakim, J; Pedruzzi, E; Périanin, A | 1 |
| Ali, H; Didsbury, JR; Richardson, RM; Snyderman, R; Tomhave, ED | 1 |
| Arai, M; Nozawa, R; Sasaki, Y | 1 |
| Frojmovic, MM; Rochon, YP | 1 |
| Lambeth, JD; Perry, DK; Stevens, VL; Widlanski, TS | 1 |
| Dang, Y; Edwards, SW; Galvani, DW; Lowe, GM | 1 |
| Kochanek, PM; Nemoto, EM; Schiding, JK; Uhl, MW | 1 |
| Badwey, JA; Robinson, JM | 1 |
| Jaconi, ME; Krause, KH; Lew, DP; Monod, A | 1 |
| Arcaro, A; Wymann, MP | 1 |
| Dusi, S; Rossi, F | 1 |
| Hawkins, PT; Jackson, TR; Stephens, L | 1 |
| Chollet-Martin, S; Gourgon, R; Hakim, J; Himbert, D; Huu, TP; Juliard, JM; Pasquier, C; Pocidalo, MA; Steg, PG | 1 |
| Bidlingmaier, F; Schöndorf, M; von Ruecker, AA | 1 |
| Ledenev, AV; Muzykantov, VR; Puchnina-Artushenko, EA; Ruuge, EK | 1 |
| Chapman, PB; Houghton, AN; Minasian, LM; Morrison, ME; Nathan, CF; Rosenblum, M; Steffens, T; Szatrowski, TP; Williams, L | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Maekawa, N; Mikawa, K; Nakamura, H; Nishina, K; Obara, H; Uetani, Y; Yaku, H | 1 |
| Anjo, S; Arai, T; Ishibashi, Y; Osaki, E | 1 |
| Danø, K; Ellis, V; Hansen, NE; Høyer-Hansen, G; Pedersen, TL; Plesner, T; Ploug, M; Rønne, E; Tscherning, T; Wittrup, M | 1 |
| Jialal, I; Scaccini, C | 1 |
| Raffin, TA; Schumann, MA | 1 |
| Herr, GP; Plachta, LB; Stroncek, DF | 1 |
| Bailie, MB; Colligan, ME; Ganey, PE; Madhukar, BV; Robinson, JP; Roth, RA; VanCise, S | 1 |
| Core, P; Muti, S; Salaffi, F; Serretti, R | 1 |
| Anthes, JC; Billah, MM; Cheewatrakoolpong, B; Egan, RW; Mullmann, TJ; Siegel, MI | 1 |
| Granger, DN; Grisham, MD; Kubes, P; Smith, R | 1 |
| Champagne, CM; Kurihara, H; Murayama, Y; Van Dyke, TE; Warbington, ML | 1 |
| Horejsi, V; Lund-Johansen, F; Olweus, J | 1 |
| Levine, M; Wang, Y; Washko, PW | 1 |
| Karnovsky, MJ; Khan, AU; Steinbeck, MJ | 1 |
| Harada, M; Nakao, M; Niho, Y; Ohhara, N; Okamura, S; Shirai, T; Umei, T | 1 |
| Kwan-Yeung, L; Wong, K | 1 |
| de Bont, DB; Hilarius, PM; Kessels, GC; Leusen, JH; Liskamp, RM; Verhoeven, AJ | 1 |
| Bengis-Garber, C; Gruener, N | 2 |
| Koide, H; Tomino, Y; Watanabe, A; Yokoyama, K | 1 |
| Goh, LB; Lee, CW; Sartorelli, AC; Sokoloski, JA | 1 |
| Hansson, A; Palmblad, J; Rosendahl, K; Samuelsson, J | 1 |
| Burkey, TH; Webster, RO | 1 |
| Badwey, JA; Ding, J | 1 |
| Saklatvala, J; Shiroo, M; Thompson, HL | 1 |
| Belohradsky, BH; Buth, S; Gahr, M; Jendrossek, V; Liese, J; Peters, AM; Wintergerst, U | 1 |
| Lewis, WH; Mustoe, TA; Porras-Reyes, BH; Roman, J; Simchowitz, L | 1 |
| Harms-Ringdahl, M; Jansson, G | 1 |
| Kanbara, T; Manabe, M; Sato, EF; Tomoda, MK; Ueda, W | 1 |
| Carr, AC; Winterbourn, CC | 1 |
| Kanaho, Y; Katoh, M; Nakai, Y; Nozawa, Y | 1 |
| Aramaki, Y; Ichimori, Y; Masuya, H; Nishinaka, Y; Sugawara, T; Yoshida, H | 1 |
| Halbwachs-Mecarelli, L; Jin, WW; Nathan, C; Xie, QW | 1 |
| Damtew, B; Goldsmith, G; Spagnuolo, PJ; Tserng, KY | 1 |
| Kessels, GC; Krause, KH; Verhoeven, AJ | 1 |
| Bashan, N; Moran, A; Moses, SW; Peist, A; Peleg, N; Potashnik, R | 1 |
| Hirvonen, MR; Savolainen, KM; Tuomala, M | 1 |
| de Groot, H; Komarov, P; Wang, JF | 1 |
| Kushnareva, TA; Muzykantov, VR; Ruuge, EK; Smirnov, MD | 1 |
| Mizuno, S; Ohoka, T; Shibata, M; Suzuki, K | 1 |
| Heimburger, M; Lerner, R; Palmblad, J | 1 |
| Daniels, I; Fletcher, J; Haynes, AP; Lindsay, M; Morgan, AG; Porter, C | 1 |
| Rathakrishnan, C; Tiku, ML | 1 |
| Antonaci, S; Jirillo, E; Ottolenghi, A; Pugliese, P; Tortorella, C | 1 |
| Bokoch, GM; Evans, T; Jesaitis, AJ; Loetterle, LR; Quinn, MT | 1 |
| Camarero, VC; Colepicolo, P; Karnovsky, ML; Ribeiro, JM | 1 |
| Geffner, JR; Isturiz, MA; Maugeri, N; Minnucci, F; Palermo, MS; Trevani, AS | 1 |
| Opdahl, H | 1 |
| Evans, AT; Evans, FJ; MacPhee, CH; Merritt, JE; Moores, KE; Sharma, P | 1 |
| Imajoh-Ohmi, S; Kanegasaki, S; Kikuchi, H | 1 |
| Dexter, TM; Haefner, B; Heyworth, CM; Owen, PJ; Shearman, MS; Whetton, AD | 1 |
| Boulay, F; Brouchon, L; Mery, L; Tardif, M | 1 |
| Curatola, G; Fiorini, R; Giorgi, PL; Gratton, E; Kantar, A | 1 |
| Anderson, DC; McNally, AC; Myones, BL; O'Gorman, MR | 1 |
| Hsiue, TR; Kulp, GV; Leff, AR; Strek, ME; White, SR; Williams, FS | 1 |
| Banks, SM; Buescher, ES; Kavanagh, JJ; Kudelka, AP; McIlheran, SM; Vadhan-Raj, S | 1 |
| Bartoleschi, C; Biselli, R; Casciaro, A; Fattorossi, A; Nisini, R | 1 |
| Huang, CK; Labadia, ME; Zu, YL | 1 |
| Heiskanen, K; Ruotsalainen, M; Savolainen, K | 1 |
| Hammerle, AF; Mayer, N; Micksche, M; Oismüller, C; Steltzer, H | 1 |
| Chap, H; Planat, V; Record, M; Ribbes, G; Tronchere, H | 1 |
| Butcher, EC; Campbell, JJ; Laudanna, C | 1 |
| Danbara, M; Ikebuchi, K; Saito, H; Sato, H; Yagisawa, M; Yuo, A | 1 |
| Bellido, ML; Lucas, M; Pedrera, C; Sänchez-Margalet, V | 1 |
| Haydek, JM; Keshavarzian, A | 1 |
| Jansson, SE; Repo, H; Vuorte, J | 2 |
| Hyvärinen, A; Nevalainen, A; Ruotsalainen, M; Savolainen, KM | 1 |
| Azuma, E; Furukawa, Y; Kitagawa, S; Masuyama, J; Takahashi, M; Takaku, F; Yagisawa, M; Yoshida, M; Yuo, A | 1 |
| Catz, SD; Steŕin-Speziale, NB | 1 |
| Leirisalo-Repo, M; Paimela, L; Repo, H | 1 |
| Chertov, O; Longo, DL; Michiel, DF; Murphy, WJ; Oppenheim, JJ; Tani, K; Taub, DD; Wang, JM; Xu, L | 1 |
| Ahuja, A; Chao, W; Oh, N; Smith, RM; Spragg, RG | 1 |
| Akamatsu, H; Kanoh, T; Kurisaka, M; Niwa, Y; Ozaki, Y | 1 |
| Guignard, F; Markert, M | 1 |
| Donini, M; Dusi, S; Rossi, F; Wientjes, F | 2 |
| Ai, Y; Gilchrist, A; Huang, CK; Labadia, ME; Sha'afi, RI; Zu, YL | 1 |
| Kambayashi, J; Kawasaki, T; Monden, M; Okuyama, M; Sakon, M | 1 |
| Dahlgren, C; Harbecke, O; Lundqvist, H | 1 |
| Heiskanen, KM; Savolainen, KM | 4 |
| Campos, A; Fernández-Segura, E; García, JM | 1 |
| Brown, EJ; Jones, SL | 1 |
| Borregaard, N; Brumell, JH; Grinstein, S; Kjeldsen, L; Nanda, A; Nordström, T; Rotstein, OD; Sengelov, H | 1 |
| Ganey, PE; Roth, RA; Wagner, JG | 1 |
| Daniels, I; Fletcher, J; Lindsay, MA | 1 |
| Embleton, MJ; Grunert, F; Jantscheff, P; Kleist, SV; Nagel, G; Price, MR; Thompson, J | 1 |
| Balazovich, KJ; Boxer, LA; Remick, DG; Suchard, SJ | 1 |
| Clough, J; Cypcar, D; Kaplan, M; Lemanske, RF; Nagata, M; Sedgwick, J; Sorkness, R | 1 |
| de Koster, BM; Elferink, JG; Van den Broek, PJ; VanSteveninck, J; VanUffelen, BE | 1 |
| Cesario, TC; Kaupke, CJ; Vaziri, ND; Yousefi, S; Zhang, J | 1 |
| Lipinski, P; Retmańska, H | 1 |
| Bambara, LM; Bellavite, P; Biasi, D; Caramaschi, P; Carletto, A; Chirumbolo, S; Corrocher, R; Guarini, P | 1 |
| Adachi, M; Ando, S; Dobashi, K; Hisada, T; Ishizuka, T; Mori, M; Morita, K | 1 |
| Dahlgren, C; Lundqvist, H | 1 |
| Dressel, M; Heptinstall, S; Krause, S; Lösche, W; Redlich, H; Spangenberg, P | 1 |
| Imada, T; Murata, H | 1 |
| Ciccarelli, A; Cirillo, R; de Crescenzo, G; de Paulis, A; Marone, G; Patella, V | 1 |
| Bengtsson, T; Grenegård, M; Olsson, A; Sjögren, F; Stendahl, O; Zalavary, S | 1 |
| Herget, J; Sojková, J; Wilhelm, J | 2 |
| Capsoni, F; Catania, A; Lipton, JM; Minonzio, F; Rajora, N; Star, RA | 1 |
| Abe, H; Obinata, T; Okada, K; Takano-Ohmuro, H | 1 |
| Brunelleschi, S; Fantozzi, R; Guidotto, S; Tonso, E; Viano, I | 1 |
| Kubo, S; Kumazawa, J; Matsumoto, T; Mizunoe, Y; Mochida, O; Sakamoto, Y; Sakumoto, M | 1 |
| Ganey, PE; Peters-Golden, M; Schiamberg, E; Tithof, PK | 1 |
| Fridrich, R; Maecke, HR; Stoeckli, TC; Zimmerli, W | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Carman, K; Ferrante, A; McPhee, A; Nandoskar, M; Poulos, A | 1 |
| Nakahata, N; Ohizumi, Y; Tsukii, K; Tsurufuji, S; Watanabe, K | 1 |
| Knol, EF; Lie, WJ; Mul, FP; Roos, D; Verhoeven, AJ | 1 |
| Fruehauf, S; Haas, R; Murea, S; Zeller, WJ | 1 |
| Guignard, F; Markert, M; Mauel, J | 1 |
| Babior, BM; El Benna, J; Han, J; Park, JW; Schmid, E; Ulevitch, RJ | 1 |
| Nagaoka, I; Saito, K; Yamashita, T; Yomogida, S | 1 |
| Ali, H; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Imajoh-Ohmi, S; Kanegasaki, S; Takaku, F; Yagisawa, M; Yazaki, Y; Yonemaru, M; Yuo, A | 1 |
| Altieri, DC; Plescia, J | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Dvorak, AM; Lichtenstein, LM; MacGlashan, DW; Morgan, ES | 1 |
| Cerletti, C; de Gaetano, G; Evangelista, V; Manarini, S; Martelli, N; McGregor, JL; Polischuk, R; Rotondo, S | 1 |
| Ambruso, DR; Cusack, N; Malech, HL; Peterson, VM; Rosenthal, J; Thurman, GW | 1 |
| Donini, M; Dusi, S; Rossi, F | 1 |
| Meyer, CN; Nielsen, H | 1 |
| D'Amico, R; Derevianko, A; Simms, H | 1 |
| Bambara, LM; Bellavite, P; Biasi, D; Caramaschi, P; Carletto, A; Dell'Agnola, C; Montesanti, F; Zavateri, G; Zeminian, S | 1 |
| Anderson, R; Feldman, C; Theron, AJ | 1 |
| Akiyama, J; Ando, M; Kudo, T; Yoshioka, T | 1 |
| Maridonneau-Parini, I; Welch, H | 2 |
| Badruzzaman, M; Shimoyama, M; Terashima, M; Tsuchiya, M | 1 |
| Aitken, RJ; Allan, IW; Irvine, DS; Macnamee, M | 1 |
| Paradowski, PT; Pietruszyński, R; Zeman, K | 1 |
| Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Luyckx, M; Moutard, I | 1 |
| Cohen, HJ; De La Paz, MA; Hatchell, DL; Rao, KM | 1 |
| Dubois, T; Geny, B; Lukowski, S; Mira, JP; Oudinet, JP; Russo-Marie, F | 1 |
| Hong, KW; Kim, CD | 1 |
| KuKuruga, MA; Model, MA; Todd, RF | 1 |
| Gahr, M; Heyden, S; Jendrossek, V; Neubauer, B; Ritzel, A | 1 |
| Ahlin, A; Elinder, G; Palmblad, J | 1 |
| Bald, A; Cassatella, MA; McDonald, PP | 1 |
| Kock, JL; Nigam, S; Roux, MP | 1 |
| Arakawa, S; Fujisawa, M; Kamidono, S; Kanzaki, M; Okada, H; Tatsumi, N | 1 |
| Damtew, B; Spagnuolo, PJ | 1 |
| Hsu, MF; Lin, CN; Raung, SL; Tsao, LT; Wang, JP | 1 |
| Arfors, KE; Chambers, JD; Messmer, K; Peter, K; Thiel, M; von Andrian, UH; Zourelidis, C | 1 |
| Boveris, A; Carreras, MC; Pargament, GA; Poderoso, JJ; Riobó, NA | 1 |
| Agarwal, A; Brackett, NL; Lynne, CM; Padron, OF; Sharma, RK; Thomas, AJ | 1 |
| Tsao, LT; Wang, JP | 1 |
| Berto, L; Bruseghini, L; Cortijo, J; Esteras, A; Martí-Cabrera, M; Morcillo, EJ; Ortiz, JL; Villagrasa, V | 1 |
| Galkop, S; Katz, A; Levy, R; Riesenberg, K; Schlaeffer, F | 1 |
| Iijima, S; Otsuka, F | 1 |
| Benna, JE; Dang, PM; Fay, M; Gaudry, M; Gougerot-Pocidalo, MA; Hakim, J; Morel, F | 1 |
| Harris, H; Hojman, H; Horn, JK; Lounsbury, D | 1 |
| Butler, J; Downey, GP; Fialkow, L; Grinstein, S; Schelm, JA; Sue-A-Quan, AK; Vlahos, CJ | 1 |
| Garcia del Saz, E; Kobayashi, T; Okada, T; Seguchi, H | 1 |
| Bambara, LM; Bellavite, P; Biasi, D; Caramaschi, P; Carletto, A; Pacor, ML; Zeminian, S | 1 |
| Kapus, A; Ligeti, E; Mócsai, A; Suszták, K | 1 |
| Ferrante, A; Hii, CS; Huang, ZH; Murray, AW; Poulos, A; Rathjen, DA | 1 |
| Aitken, J; Bramley, T; Rae, M; Sakka, E | 1 |
| Brun-Buisson, C; Delacourt, C; Delclaux, C; Harf, A; Lafuma, C; Rezaiguia-Delclaux, S | 1 |
| Katagiri, Y; Nakamura, M; Nakashima, S; Nozawa, Y | 1 |
| Brunet, J; Féray, JC; Garay, RP; Hannaert, P; Mohammadi, K; Taouil, K | 1 |
| Harford, F; Haydek, JM; Holmes, EW; Jacyno, M; Keshavarzian, A | 1 |
| Jackson, CG; Stewart, A; Wakelam, MJ | 1 |
| Itoh, Y; Kashima, K; Nakagawa, Y; Nishioji, K; Okanoue, T; Sakamoto, K; Sakamoto, S; Yoshida, N; Yoshikawa, T | 1 |
| Brunet, C; Cabanis, A; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Luyckx, M | 1 |
| Gay, JC; Murray, JJ; Raddassi, K; Truett, AP | 1 |
| Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Okuda, A; Sawada, M; Usami, I; Watanabe, K | 1 |
| Heiskanen, KM; Krombach, F; Münzing, S; Savolainen, KM | 1 |
| Farkas, L; Geiszt, M; Kapus, A; Ligeti, E; Német, K | 1 |
| Badwey, JA; Ding, J; Ellis, BA; Heyworth, PG; Robinson, JM | 1 |
| Bokoch, GM; Chang, P; Cox, D; Greenberg, S; Reddy, PG; Zhang, Q | 1 |
| Babcock, GF; Morris, RE; Rodeberg, DA | 1 |
| Bobanović, F; Kotnik, V; Simcic, S; Vodovnik, L | 1 |
| Osaki, T; Ueta, E; Yamamoto, T; Yoneda, K | 1 |
| Ahmed, N; Berridge, MV; Kansara, M | 1 |
| Eisterer, W; Greil, R; Hilbe, W; Ludescher, C; Thaler, J; Zabernigg, A | 1 |
| Exton, JH; Guillemain, I | 1 |
| Ahmed, N; Berridge, MV; Tan, AS | 1 |
| Higashi-Okai, K; Okai, Y | 1 |
| Capodici, C; Feoktistov, M; Hanft, S; Pillinger, MH | 1 |
| García del Saz, E; Jiang, X; Kobayashi, T; Nahirney, PC; Seguchi, H | 2 |
| Aviram, I; Irit, A; Michaela, S; Sharabani, M; Tal, T | 1 |
| Davies-Hill, TM; Levine, M; Malide, D; Simpson, IA | 1 |
| Caimi, G; Canino, B; Catania, A; Ferrara, F; Lo Presti, R; Meli, F; Montana, M; Ventimiglia, G | 1 |
| Bokoch, GM; Brown, EJ; Jones, SL; Knaus, UG | 1 |
| Hirai, S; Okamoto, K; Sotomatsu, A; Tanaka, M; Yoshida, T | 1 |
| Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Levert, H; Luyckx, M; Moutard, I | 1 |
| Hayakawa, T; Yamaguchi, T | 1 |
| Cockcroft, S; Fensome, A; Jones, D; Morgan, C; Whatmore, J | 1 |
| Brunet, C; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Luyckx, M; Moutard, I; Templier, F | 1 |
| Bordin, G; Brunelleschi, S; Colangelo, D; Viano, I | 1 |
| Fröhlich, D; Hobbhahn, J; Rothe, G; Schmid, P; Schmitz, G; Taeger, K; Wittmann, S | 1 |
| Bennett, JS; Loh, E; Qi, W; Vilaire, G | 1 |
| Gajate, C; Lazo, PA; Martín-Martín, B; Mollinedo, F | 1 |
| Ambruso, DR; Gonzalez-Aller, C; Leavey, PJ; Thurman, G; Zerbe, G | 1 |
| Galkina, SI; Margolis, LB; Sud'ina, GF; Ullrich, V | 1 |
| Kodama, H; Kurashige, T; Masuoka, N; Ohta, J; Sagara, Y; Shimazaki, Y; Ubuka, T; Wakiguchi, H; Zhang, J | 1 |
| Lord, JM; Pongracz, J | 1 |
| Gyllenhammar, H; Lärfars, G | 1 |
| Aitken, RJ; Fulton, N; Houston, P; Irvine, DS; Michael, L; Twigg, J | 1 |
| Kato, M; Morikawa, A; Takei, K; Tokuyama, K | 1 |
| Catravas, JD; Chen, X | 1 |
| Kula, P; Kurmanowska, Z; Nowak, D; Stolarek, R | 1 |
| MacGlashan, DW; Miura, K | 1 |
| Hakki, ZW; Kim-Park, WK; Kowolik, MJ; Moore, MA | 1 |
| Anderson, KL; Maki, RA; Pio, F; Smith, KA; Torbett, BE | 1 |
| Frydrychová, M; Hezinová, A; Vízek, M; Wilhelm, J | 1 |
| Burke-Gaffney, A; Hellewell, PG | 1 |
| Borgeat, P; Bourgoin, S; Créminon, C; Gilbert, C; Maclouf, J; McColl, SR; Naccache, PH; Poubelle, PE; Pouliot, M | 1 |
| Bernstein, PR; Bonuccelli, CM; Cao, GL; Huang, YI; Meng, M; Pou, S; Rosen, GM; Salcedo, TW; Strimpler, A; Surichamorn, W; Veale, C | 1 |
| Bei, L; Hu, T; Qian, ZM; Shen, X | 1 |
| Giroud, JP; Hakim, J; Pédruzzi, E; Périanin, A | 1 |
| Chirumbolo, S; Guidi, G; Lippi, G | 1 |
| Annoni, G; Braga, PC; Dal Sasso, M; Pecile, A; Sala, MT; Vergani, C | 1 |
| Kilpatrick, LE; Korchak, HM; Rossi, MW | 1 |
| Culpepper, S; Danner, RL; Lam, C; Tuschil, AF; Van Dervort, AL; Wesley, RA | 1 |
| Hubbard, WC; MacGlashan, DW; Miura, K | 1 |
| Daniel, WG; Garlichs, CD; Mügge, A; Zhang, H | 2 |
| Anastasiou-Katsiardani, A; Dimitriadou-Georgiadou, A; Kadiltsoglou, I; Panteliadis, C; Roilides, E; Tsaparidou, S; Walsh, TJ | 1 |
| Capodici, C; Hanft, S; Kheterpal, N; Philips, MR; Pillinger, MH; Rosenthal, P; Weissmann, G | 1 |
| Huang, LJ; Kuo, SC; Raung, SL; Wang, JP | 1 |
| Genovese, K; Holtzapple, C; Kogut, MH; Lowry, VK; Stanker, LH | 1 |
| Boulay, F; Christophe, T; Milcent, MD; Rabiet, MJ; Tardif, M | 1 |
| Arai, H; Horiuchi, H; Kita, T; Nishioka, H | 1 |
| Hazeki, K; Hazeki, O; Kodama, T; Okada, T; Ui, M | 1 |
| Jutila, KL; Nelson, LK; Quinn, MT; Rohn, TT; Sipes, KM; Swain, SD | 1 |
| Chung, BS; Kim, IH; Kwak, JY; Park, JI; Uhlinger, DJ | 1 |
| Atger, V; Cogny, A; Lenoble, M; Moatti, N; Paul, JL; Surbled, B | 1 |
| Caimi, G; Canino, B; Catania, A; LoPresti, R; Montana, M; Ventimiglia, G | 1 |
| Caimi, G; Canino, B; Cerasola, G; Ferrara, L; Lo Presti, R; Montana, M; Oddo, G; Ventimiglia, G | 1 |
| Bohbot, A; Didier, A; Loor, F; Tiberghien, F | 1 |
| Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M | 1 |
| Betsuyaku, T; Brown, EJ; Haug, JS; Jones, SL; Link, DC; Liu, F; Matsushima, K; Senior, RM | 1 |
| Budhu, S; Cao, L; El Khoury, J; Hoffman, S; Loike, JD; Marcantonio, EE; Silverstein, SC; Yednock, TA | 1 |
| Bengtsson, T; Lundqvist-Gustafsson, H | 1 |
| Fujiwara, T; Hasui, M; Hattori, K; Kinoshita, Y; Kobayashi, Y; Taniuchi, S; Yamamoto, A | 1 |
| Kondo, M; Miyajima, T; Naito, Y; Nakagawa, S; Nakamura, Y; Tanigawa, T; Yoshida, N; Yoshikawa, T | 1 |
| Baj, Z; Czekalska, R; Janiszewska-Drobinska, B; Kosmider, M; Kowalski, J; Pasnik, J; Zeman, K | 1 |
| Greve, B; Kremsner, PG; Lehman, LG; Lell, B; Luckner, D; Schmidt-Ott, R | 1 |
| Chang, LC; Raung, SL; Shen, AY; Tsao, LT; Wang, JP | 1 |
| Kodama, H; Seto, K; Sugahara, K; Ushikoshi, I; Ushikoshi, S; Zhang, J | 1 |
| Dobos, G; Elsner, J; Löer, D; Melchart, D; Michalsen, A; Völker, K | 1 |
| Bautsch, W; Bock, D; Gärtner, S; Klos, A; Köhl, J; Rheinheimer, C; Saad, H; Settmacher, B | 1 |
| Clifton, AD; Cohen, P; Lal, AS; Rouse, J; Segal, AW | 1 |
| Akasaki, T; Koga, H; Sumimoto, H | 1 |
| Kodama, H; Meng, Z; Sagara, Y; Sugahara, K; Xu, S; Zhang, J; Zhang, M | 1 |
| Bei, L; Hu, TH; Qian, ZM; Shen, X | 1 |
| Hirai, H; Kitagawa, S; Kitamura, T; Okuma, E; Saeki, K; Takaku, F; Yagisawa, M; Yazaki, Y; Yuo, A | 1 |
| Anderson, R; Feldman, C; Mokgobu, I; Theron, AJ | 1 |
| Håkansson, L; Xu, X | 3 |
| Bos, JL; Coffer, PJ; Koenderman, L; M'Rabet, L; Wolthuis, RM; Zwartkruis, F | 1 |
| Ko, HH; Lin, CN; Lin, HC; Wang, JJ; Wang, JP | 1 |
| Brown, EJ; Wang, J | 1 |
| Novak, MJ; Yan, SR | 1 |
| Brown, GE; Burke, PA; Forse, RA; Xu, J; Yaffe, MB | 1 |
| Ford, GA; Noble, JM; Thomas, TH | 1 |
| Arnautova, IP; Gamaleĭ, IA; Kirpichnikova, KM; Kliubin, IV | 1 |
| Grunert, F; Hönig, M; Jantscheff, P; Peter, HH | 1 |
| Daniel, WG; Garlichs, CD; Schmeisser, A; Zhang, H | 1 |
| Caimi, G; Canino, B; Cerasola, G; Lo Presti, R; Montana, M | 1 |
| Arfors, KE; David, G; Dedio, J; Flodgaard, H; Herwald, H; Linde, V; Lundgren-Akerlund, E; Müller-Esterl, W; Olofsson, AM; Rygaard, J; Vestberg, M | 1 |
| Akiyama, J; Horton, AA; Ishisaka, R; Kanematsu, H; Kanno, T; Nakahara, H; Yasuda, T; Yoshioka, T | 1 |
| Carpentier, JL; Cartier, L; Foti, M; Krause, KH; Lew, DP; Piguet, V; Trono, D | 1 |
| Barnes, PJ; Giembycz, MA; Hellewell, PG; Lindsay, MA; Lynch, OT | 1 |
| Orie, NN; Tepel, M; Zidek, W | 1 |
| Attardo, G; Burt, H; Jackson, JK; Pelech, SL; Tudan, C | 1 |
| Banno, Y; Dohi, S; Nakashima, S; Nozawa, Y; Ohguchi, K; Ono, Y; Tan, Z | 1 |
| Bourgoin, S; Houle, MG; Naccache, PH | 1 |
| Gorobchenko, AN; Grachev, SV; Malov, VA; Pak, SG; Roslyĭ, IM | 1 |
| Dahouk, S; Gerngross, H; Kaffenberger, W; Plappert, UG; Starck, C; Willy, C | 1 |
| Argenzio, RA; Blikslager, AT; Rhoads, JM; Roberts, MC; Young, KM | 1 |
| Boxer, LA; Gunning, WT; Keil, ML; Lachant, NA; Ochs, HD; Omann, GM; Rengan, R; Sweet, LI | 1 |
| Aarnes, H; Fonnum, F; Myhre, O; Sagstuen, E; Vestad, TA | 2 |
| Bailleul, F; Brunet, C; Cazin, JC; Cazin, M; Daels-Rakotoarison, DA; Dine, T; Gressier, B; Luyckx, M; Seidel, V; Tillequin, F | 1 |
| Chen, JS; Chen, LW; Shen, AY; Wu, SN | 1 |
| Alexander, SR; Kishimoto, TK; Walcheck, B | 1 |
| Hirota, S; Nagaoka, I | 1 |
| Gaspirc, B; Manthey, CM; Mergenhagen, SE; Skaleric, U; Wahl, SM | 1 |
| Klemm, J; Rådmark, O; Samuelsson, B; Werz, O | 1 |
| Bridts, CH; De Clerck, LS; Mertens, AV; Moens, MM; Stevens, WJ | 1 |
| Chang, CY; Chen, PQ; Ho, KJ; Lu, FJ | 1 |
| Cattaneo, S; Cosentino, M; Di Grazia, L; Fietta, AM; Francioli, C; Frigo, G; Lecchini, S; Marino, F | 1 |
| Campa, A; Ferreira Novo, N; Julian, Y; Rebecchi, IM | 1 |
| Buthmann, U; Freund, M; Kleine, HD; Volk, J | 1 |
| Katsura, Y; Matsuoka, T; Ohsaka, A; Takagi, S; Takahashi, K | 1 |
| Dunzendorfer, S; Wiedermann, CJ | 1 |
| Forslund, T; Nilsson, HM; Sundqvist, T | 1 |
| Bonaventura, V; Caimi, G; Canino, B; Lo Presti, R; Montana, M; Scarpitta, AM; Sinagra, D | 1 |
| Conigrave, AD; Morris, MB; van der Weyden, L | 1 |
| Fujimura, A; Harada, K; Kawaguchi, A; Ohmori, M; Sugimoto, K; Tsuruoka, S | 1 |
| Campbell, EJ; Campbell, MA; Owen, CA | 1 |
| Kanamori, Y; Kanamura, M; Kohno, K; Kozawa, O; Matsuno, H; Niwa, M; Uematsu, T | 1 |
| Boucher, D; Grizard, G; Motta, C; Saez, F | 1 |
| D'Inca, R; D'Odorico, A; Di Leo, V; Ferronato, A; Mestriner, C; Sturniolo, GC | 1 |
| Heiskanen, KM; Komulainen, H; Pennanen, SM; Savolainen, KM | 1 |
| Arnhold, J; Arnold, K; Benard, S; Reichl, S; Schiller, J | 1 |
| Reinisch, N; Ricevuti, G; Wiedermann, CJ | 1 |
| Aziz, KA; Davey, PC; Hunt, JA; Kamiguti, AS; Zuzel, M | 1 |
| Anderson, R; Mahomed, AG | 1 |
| Himmelfarb, J; McMonagle, E | 1 |
| Adzet, T; Cañigueral, S; Pérez-García, F | 1 |
| Erjefält, JS; Malm-Erjefält, M; Persson, CG | 1 |
| Naber, T; van Emst-De Vries, S; Wanten, G; Willems, P | 1 |
| Kawamura, Y; Nakatani, K; Sekine, I; Takeshita, S; Tsujimoto, H | 1 |
| Kodama, H; Lu, J; Meng, Z; Sugahara, K; Xu, S; Zhou, Y | 1 |
| Tou, J; Urbizo, C | 1 |
| Ball, BA; Baumber, J; Vo, AT | 1 |
| Rosen, SD; Strausbaugh, HJ | 1 |
| Badwey, JA; Lian, JP; Toker, A | 1 |
| Kahler, CP | 1 |
| Alvarez, E; Ruiz-Gutiérrez, V; Santa-María, C; Sobrino, F | 1 |
| Brand, C; Carson, CF; Ferrante, A; Finlay-Jones, JJ; Hart, PH; Prager, RH; Riley, TV | 1 |
| Danihelová, E; Drábiková, K; Jancinová, V; Nosál, R | 1 |
| Leto, TL; Levy, R; Malech, HL; Pessach, I | 1 |
| Barbin, L; Cariani, A; Dovigo, L; Fabbri, E; Muccinelli, M; Spisani, S; Trotta, F | 1 |
| Caldwell, RB; Catravas, JD; Ehrhart, IC; Gu, X; Parkerson, JB; Theodorakis, MJ; Zou, L | 1 |
| Cotter, MJ; Hellewell, PG; Norman, KE; Ridger, VC | 1 |
| Asaka, Y; Kodama, H; Lu, HW; Manabe, M; Masuoka, N; Sagara, Y; Sugahara, K | 1 |
| Angelisová, P; Cerný, J; Drbal, K; Hilgert, I; Horejsí, V; Novák, P | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Al-Ghoul, WM; Choudhry, MA; Fazal, N; Sayeed, MM | 1 |
| Biffl, WL; Ciesla, DJ; Gonzalez, RJ; Moore, EE; Moore, HB; Silliman, CC | 1 |
| Fardon, NJ; Thomas, TH; Wilkinson, R | 1 |
| Chen, J; Cheng, GF; Wang, WJ; Zhang, JT; Zhong, M; Zhu, XY | 1 |
| Andrews, RP; Kepley, CL; Oliver, JM; Wilson, BS; Youssef, L | 1 |
| Hanson, AJ; Quinn, MT; Siemsen, DW; Swain, SD | 1 |
| Brunelleschi, S; Colangelo, D; Gaudino, G; Lavagno, L; Penengo, L; Santoro, C; Viano, I | 1 |
| Kodama, H; Ma, D; Sagara, Y; Sugahara, K; Zhang, J | 1 |
| Feng, X; Kodama, H; Lu, H; Lu, J; Ma, D; Manabe, M; Sagara, Y; Sugahara, K; Sun, Q | 1 |
| Cíz, M; Lojek, A | 1 |
| Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J | 1 |
| Naber, T; Rops, A; van Emst-De Vries, SE; Wanten, G; Willems, PH | 1 |
| Bourgoin, SG; Brindley, DN; Gagnon, S; Harbour, D; Houle, MG; Morris, AJ; Singh, IN | 1 |
| Tou, JS | 1 |
| Martínez, AM; Montoya, CJ; Olarte, JC; Velilla, PA | 1 |
| Cadwallader, KA; Chilvers, ER; Jones, HA; Peters, AM; Uddin, M; White, JF | 1 |
| Bordigoni, P; Demaurex, N; Lardy, B; Martel, C; Maturana, A; Morel, F; Rousseau, P; Stasia, MJ | 1 |
| Fujiu, T; Kato, M; Kimura, H; Mirza, ZN; Mochizuki, H; Morikawa, A; Suzuki, M; Tachibana, A; Tokuyama, K | 1 |
| Bussière, FI; Fauquert, JL; Labbe, A; Mazur, A; Rayssiguier, Y; Tridon, A | 1 |
| Ball, BA; Baumber, J; Sabeur, K; Vo, A | 1 |
| Advani, A; Marshall, SM; Thomas, TH | 1 |
| Fraile, G; Medina, R; Navarro, M; Reggio, R; Vásquez, F; Velásquez, M | 1 |
| Campbell, WB; Pratt, PF; Rosolowsky, M | 1 |
| Hansen, PS; Nielsen, H; Petersen, SB; Varning, K | 1 |
| Boetticher, E; Lambertino, A; Leff, AR; Meliton, A; Munoz, NM; Myo, S; Myou, S; Zhu, X | 1 |
| Appelbaum, A; Fisher, A; Greemberg, L; Levy, R; Rachinsky, M; Roytblat, L; Shapira, Y; Zilberstein, G | 1 |
| Buhre, W; de Rossi, LW; Gass, F; Horn, NA; Hutschenreuter, G; Rossaint, R | 1 |
| Bloodsworth, A; Clark, SR; Coles, B; Cross, AR; Freeman, BA; Lewis, MJ; O'Donnell, VB | 1 |
| Borregaard, N; Calafat, J; Kjeldsen, L; Sørensen, OE; Udby, L | 1 |
| Chen, G; Kodama, H; Lu, H; Manabe, M; Meng, Z; Wang, C; Xu, S; Yamashita, K | 1 |
| De Rossi, L; Gott, K; Hecker, K; Horn, N; Hutschenreuter, G; Rossaint, R | 1 |
| Bhattacharjee, AK; Casey, D; Cassels, FJ; Cross, AS; Drysdale, BE; Farese, A; Goldblum, SE; Grange, PA; Held, TK; Kleinberg, M; Powell, J; Rifat, S; Sakarya, S; Stamatos, N; Wang, LX | 1 |
| Ainis, T; Baranovskaia, G; Cavallaro, A; Fimiani, V; Ketlinskaya, O; Kozhemyakin, L | 1 |
| Chen, G; Kodama, H; Lu, H; Manabe, M; Wang, C; Yamashita, K | 1 |
| Cíz, M; Danihelová, E; Drábiková, K; Lojek, A; Nosál, R | 1 |
| Jennings, SC; Lee, VM; Ng, LL; Quinn, PA | 1 |
| Fagergren, A; Forslid, J; Jacobson, SH; Johansson, SG; Lundahl, J; Wikman, A | 1 |
| Kato, M; Kimura, H; Kobayashi, Y; Kozawa, K; Kuroiwa, M; Minakami, H; Morikawa, A; Oshima, S | 1 |
| Ozaki, Y; Rile, G; Takafuta, T; Yatomi, Y | 1 |
| Bovio, C; Braga, PC; dal Sasso, M; Sgaragli, GP | 1 |
| Lin, CN; Tsao, LT; Wang, JP; Weng, JR | 1 |
| Bonnefont-Rousselot, D; Gardès-Albert, M; Jore, D; Legrand, A; Peynet, J; Raji, B; Vasson, MP; Walrand, S | 1 |
| Abrahamson, JA; D'Alessio, KJ; Erickson-Miller, CL; Fischer, EI; Freeman, SD; Holmes, SD; Hopson, CB; Kikly, KK; King, AG | 1 |
| Maxová, H; Sisková, A; Vanková, M; Wilhelm, J | 1 |
| Guo, RF; Huber-Lang, MS; Lu, KT; McGuire, SR; Padgaonkar, VA; Sarma, JV; Ward, PA; Weber, CH; Younkin, EM; Zetoune, FS; Zuiderweg, ER | 1 |
| Heine, J; Jaeger, K; Juettner, B; Piepenbrock, S; Scheinichen, D; Zhao, J | 1 |
| Homburg, CH; Knol, EF; Kuijpers, TW; Lie, WJ; Mul, FP; Roos, D; Tool, AT | 1 |
| Betten, A; Dahlgren, C; Hellstrand, K; Hermodsson, S | 1 |
| Chen, G; Kitaoka, N; Kodama, H; Lu, H; Manabe, M; Sagara, Y; Song, S; Wang, Z; Xu, S | 1 |
| Bailleul, F; Brunet, C; Daels-Rakotoarison, DA; Dine, T; Gressier, B; Kouakou, G; Luyckx, M; Trotin, F | 1 |
| Badwey, JA; Ge, Q; Ohira, T; VanDyke, T; Zhan, Q | 1 |
| Chen, CF; Liou, KT; Shen, YC; Tsai, SK; Tsao, CM | 1 |
| Bani Sacchi, T; Bani, D; Masini, E; Nistri, S; Novelli, A; Vannacci, A | 1 |
| Német, K; Selmeczy, Z; Szelényi, J; Vizi, ES | 1 |
| Ciz, M; Kubala, L; Lojek, A; Nickova, K; Ruzickova, J; Sandula, J | 1 |
| Klink, M; Sulowska, Z; Tchorzewski, H | 1 |
| Balakrishnan, VS; Cendoroglo, M; Guo, D; Jaber, BL; King, AJ; Pereira, BJ; Rao, M; Sundaram, S | 1 |
| Strand, E; Videm, V | 1 |
| Buhre, W; de Rossi, LW; Horn, NA; Hutschenreuter, G; Rossaint, R; Stevanovic, A | 1 |
| Kim, CH; Kim, HM; Park, SY; Park, WH | 1 |
| Bialasiewicz, P; Dudkiewicz, B; Nowak, D; Wlodarczyk, A | 1 |
| Fraczek, M; Kurpisz, M; Sanocka, D | 1 |
| Thom, SR | 1 |
| Caimi, G; Canino, B; Casciolo, MF; Catania, A; Dispensa, F; Hoffmann, E; Incalcaterra, E; Lo Presti, R; Montana, M | 1 |
| Fröhlich, D; Rothe, G; Sessler, DI; Taeger, K; Vogel, P; Wittmann, S | 1 |
| Bordigoni, P; Bost-Bru, C; Brion, JP; Durant-Vital, D; Floret, D; Gatel, P; Guillot, M; Li, XJ; Maquet, E; Martel, C; Michel, G; Morel, F; Stasia, MJ; Voelckel, MA | 1 |
| Caimi, G; Canino, B; Carollo, C; Lo Presti, R; Montana, M; Porretto, F; Vaccaro, F | 1 |
| Caimi, G; Canino, B; Ferrara, F; Lo Presti, R; Montana, M | 1 |
| Brockbank, S; Downey, D; Elborn, JS; Ennis, M | 1 |
| Chen, YZ; Jiang, CL; Liu, L; Liu, Y; Long, F; Sun, HW; Wang, YX; Zhou, J | 1 |
| Gao, XP; Lin, P; Malik, AB; Welch, EJ; Ye, RD | 1 |
| Atzeni, F; Bonara, P; Capsoni, F; Carrabba, M; Doria, A; Minonzio, F; Sarzi-Puttini, P | 1 |
| Kuan, YH; Lin, CN; Lin, RH; Tsao, LT; Wang, JP | 1 |
| Chiesa, ME; Elola, MT; Fink, NE | 1 |
| Fifadara, NH; Nagarajan, S; Selvaraj, P | 1 |
| Liao, XL; Lou, B; Ma, J; Wu, MP | 1 |
| Inoue, T; Matsui, T; Niide, O; Ochiai, T; Ra, C; Suda, T; Suzuki, H; Suzuki, Y; Yoshimaru, T | 1 |
| Fröhlich, D; Rothoerl, R; Trabold, B; Wittmann, S; Woertgen, C | 1 |
| Kato, M; Kimura, H; Tachibana, A; Yamaguchi, T | 1 |
| Dvorak, AM | 1 |
| Araki, N; Hashimoto, M; Imoto, S; Jyokei, Y; Kishimoto, M; Kumagai, S; Saigo, K; Takenokuchi, M; Taniguchi, K | 1 |
| Alam, CA; Brown, J; Carrier, M; Colville-Nash, PR; Divwedi, A; Freemantle, C; Gustafson, S; Perretti, M; Seed, MP; West, DC; Willoughby, DA | 1 |
| Dinauer, MC; Kim, C | 1 |
| Chen, Y; Hashiguchi, N; Junger, WG; Yip, L | 1 |
| Braga, PC; Culici, M; Dal Sasso, M; Galastri, L; Guffanti, EE; Marceca, MT | 1 |
| Chang, S; Chou, YC; Hou, YC; Lin, LC; Liou, KT; Shen, YC; Wang, WY; Wang, YH | 1 |
| Kodama, H; Liu, G; Manabe, M; Song, SJ; Yagi-Chaves, SN; Yamashita, K | 1 |
| Beck-Oldach, K; Horowitz, JD; Kennedy, JA; McFadden-Lewis, K; Murphy, GA; Wong, YW; Zhang, Y | 1 |
| Collino, M; Dianzani, C; Fantozzi, R; Gallicchio, M; Menicagli, R; Samaritani, S; Signore, G | 1 |
| Gruber, J; Hochegger, K; Lhotta, K | 1 |
| Chouker, A; Hoelzl, A; Hummel, T; Kaufmann, I; Peter, K; Schliephake, F; Thiel, M | 1 |
| Anderson, K; Davidson, K; Ellson, C; Hawkins, PT; Stephens, LR | 1 |
| Alfinito, F; Barone, L; Becchimanzi, C; Cacciapuoti, C; Rotoli, B; Ruggiero, G; Sica, M; Terrazzano, G | 1 |
| Asberg, AE; Videm, V | 1 |
| Chilvers, ER; Coadwell, J; Condliffe, AM; Davidson, K; Ellson, CD; Ferguson, GJ; Guillou, H; Hawkins, PT; Stephens, L; Suire, S; Turner, M; Welch, H | 1 |
| Demkow, U; Jakubczak, B; Popko, K; Wasik, M | 1 |
| Ding, Y; Hasturk, H; Kantarci, A; Malabanan, A; Trackman, PC; Van Dyke, TE | 1 |
| Chang, S; Chen, CF; Chen, CH; Chen, CM; Chen, KT; Hou, YC; Ko, HC; Liou, KT; Shen, YC; Wang, WY; Wang, YH | 1 |
| Borregaard, N; Christensen, EI; Jacobsen, LC; Theilgaard-Mönch, K | 1 |
| Bollinger, J; Cherny, VV; DeCoursey, TE; Finnegan, A; Gelb, MH; Morgan, D | 1 |
| Barg, W; Bigda, A; Dobek, R; Dor, A; Gladysz, U; Gogolewski, G; Kulczak, A; Liebhart, E; Liebhart, J; Medrala, W; Panaszek, B | 1 |
| Autenrieth, IB; Bohn, E; Essin, K; Gollasch, M; Kettritz, R; Kraus, D; Luft, FC; Peschel, A; Ruth, P; Salanova, B; Sausbier, M | 1 |
| Barkhausen, T; Hildebrand, F; Krettek, C; Riedemann, NC; Winter, SW; Wrann, CD | 1 |
| Andersen, O; Bergström, T; Dahlgren, C; Hellstrand, K; Lindh, M; Mossberg, N; Movitz, C; Nilsson, S; Svedhem, A | 1 |
| Bokoch, G; Cudre-Maroux, C; Rasmussen, I; Roepstorff, K; Salmon, P; Sawada, M; van Deurs, B; Vilhardt, F | 1 |
| Bitzinger, DI; Dittmar, MS; Lindner, R; Schlachetzki, F; Trabold, B | 1 |
| Chou, CY; Chou, YC; Lee, CH; Li, CH; Liao, JF; Liou, KT; Shen, YC; Wang, YH | 1 |
| Cherny, VV; DeCoursey, TE; MacGlashan, DW; Morgan, D; Musset, B; Ríos, E; Thomas, LL | 1 |
| Chen, R; Huang, C; Jiao, B; Liu, X; Shang, Y | 1 |
| Ahluwalia, J | 1 |
| Avendaño, A; Marin, L; Marin, P; Petriz, J; Sales-Pardo, I | 1 |
| Gende, OA; Giambelluca, MS | 1 |
| Cupanikova, D; Lojek, A; Macickova, T; Nosal, R; Pecivova, J; Pekarova, M | 1 |
| Curi, R; Hatanaka, E; Lambertucci, RH; Newsholme, P; Vinolo, MA | 1 |
| de la Rebière, G; Deby, C; Deby-Dupont, G; Franck, T; Kohnen, S; Niesten, A; Serteyn, D | 1 |
| Basile, G; Bodrato, N; Bruzzone, S; De Flora, A; Ferraris, C; Franco, L; Fresia, C; Guida, L; Moreschi, I; Salis, A; Scarfì, S; Usai, C; Verderio, C; Zocchi, E | 1 |
| Ahluwalia, J; Salmon, MD | 1 |
| Fraser, JF; Fung, YL; Tung, JP; Wood, P | 1 |
| Adler, KB; Eckert, RE; Jones, SL; Neuder, LE; Park, J | 1 |
| Alarcón, J; Figueroa, G; Pastene, E; Speisky, H; Troncoso, M | 1 |
| Borregaard, N; Cowland, JB; Garred, P; Honore, C; Jacobsen, LC; Larsson, LI; Ohlsson, S; Pedersen, CC; Rørvig, S | 1 |
| Hyun, YM; Kim, M; Knauf, PA; Law, FY; Lefort, CT; Schultz, JB; Waugh, RE | 1 |
| Olsen, GD; Videm, V | 1 |
| Crystal, GJ; Eom, W; Hu, G; Kim, SJ; Saad, MM | 1 |
| Hu, T; Liu, Z; Shen, X | 1 |
| Abe, A; Hanieh, H; Kondo, Y | 1 |
| Dhondt, A; Glorieux, G; Jankowski, J; Jankowski, V; Schepers, E; Vanholder, R | 1 |
| Bao, F; Cepinskas, G; Fleming, JC; Weaver, LC | 1 |
| Al Laham, F; Birck, R; Heeringa, P; Heinrich, L; Kallenberg, CG; Kälsch, AI; Yard, B | 1 |
| Daly, L; Maher, BM; Soo, AW; Watson, WR; Wood, AE | 1 |
| Bigot, S; Brachemi, S; Camous, L; Frémeaux-Bacchi, V; Halbwachs-Mecarelli, L; Lesavre, P; Roumenina, L | 1 |
| Kamer, B; Kamer-Bartosińska, A; Kulig, K; Lewkowicz, P; Tchórzewski, H | 1 |
| Clark, SR; Coles, B; Eberl, M; Guy, CJ; Hammond, VJ; Jones, SA; Kift-Morgan, AP; Kotecha, S; O'Donnell, VB; Roberts, GW; Scurr, MJ; Taylor, PR; Thomas, CP; Topley, N | 1 |
| Abe, H; Chen, G; Chi, H; He, W; Kodama, H; Wei, S; Yamashita, K; Yokoyama, M | 1 |
| Hessari, NM; Lee, I; Pan, L; Wu, X; Xu, J; Zhang, X; Zhao, D | 1 |
| Baseggio Conrado, A; Capuozzo, E; Fontana, M; Giovannitti, F; Pecci, L | 1 |
| Echigoya, Y; Itou, T; Morita, S; Sakai, T | 1 |
| Anderson, R; Cholo, MC; Mokgobu, MI; Steel, HC; Theron, AJ; Tintinger, GR | 1 |
| Baj, Z; Majewska, E; Rysz, J; Wittek, N | 1 |
| Bitzinger, DI; Busse, H; Graf, BM; Gruber, M; Paech, C; Sinner, B; Trabold, B; Zausig, YA | 1 |
| Favot, CL; Forster, C; Glogauer, M | 1 |
| Boussetta, T; Driss, F; El-Benna, J; Fay, M; Guichardant, M; Lagarde, M; Liu, M; Makni-Maalej, K | 1 |
| Bagetta, G; Bombelli, R; Corasaniti, MT; Cosentino, M; Luini, A; Marino, F | 1 |
| Chirkov, YY; Horowitz, JD; Liu, S; Ngo, DT; Stewart, S | 1 |
| Bienkiewicz, M; Bukowiecka-Matusiak, M; Burzynska-Pedziwiatr, I; Danikiewicz, W; Machala, W; Spolnik, G; Wojcik, M; Wozniak, LA | 1 |
| Davison, G; Jones, AW; March, DS; Thatcher, R | 1 |
| Avinoah, E; Brotfain, E; Hadad, N; Levy, R; Raichel, L; Shapira, Y; Zlotnik, A | 1 |
| Gorbet, M; Postnikoff, C; Williams, S | 1 |
| Ng, HP; Valentine, VG; Wang, G | 1 |
| Davison, G; Izzat, HJ; Jones, AW; Lewis, KE; Mohamed, P; Robinson, R | 1 |
| Douhan Håkansson, L; Sindelar, R; Stålhammar, ME | 1 |
| Arifulin, EA; Baratova, LA; Fedorova, NV; Galkina, SI; Serebryakova, MV; Stadnichuk, VI; Sud'ina, GF | 1 |
| Al-Ramadi, BK; Al-Sbiei, A; Amarante-Mendes, GP; Cabral-Marques, O; Calich, VLG; Condino-Neto, A; Costa-Carvalho, BT; da Costa, TA; Di Gesu, RSW; Feriotti, C; Fernandez-Cabezudo, MJ; Ferreira, JF; França, TT; Iqbal, A; Junior, OR; Khan, TA; Marzagão Barbuto, JA; Notarangelo, LD; Ochs, HD; Pereira, PVS; Riemekasten, G; Schimke, LF; Tavares, FS; Torgerson, TR; Valente, C; Weber, CW | 1 |
| Hashimoto, M; Imoto, S; Kawano, S; Kono, M; Matsuhiroya, S; Nishiyama, T; Obuchi, A; Saigo, K; Takahashi, T | 1 |
| Chew, CY; Chung, TH; Lam, CH; Tan, KT; Wu, YP | 1 |
| Araujo, EVO; de Sousa, JAC; Guimaraes, MA; Leal, LKAM; Leite, JRSA; Lima, DF; Machado, NJ; Rocha, TM | 1 |
| Broides, A; Hadad, N; Lev, A; Levy, J; Levy, R; Mandola, AB; Nahum, A; Rylova, A; Simon, AJ; Somech, R | 1 |
| Bredthauer, A; Gruber, M; Lehle, K; Pai, D; Pfaehler, SM; Trabold, B | 1 |
| Ciepiela, O; Demkow, U; Głodkowska-Mrówka, E; Mrówka, P; Ostafin, M; Pruchniak, M; Ulińska, E; Wachowska, M | 1 |
| Teranishi, K | 1 |
| Dixon, B; Gorbet, M; Jin, Y; Jones, L | 1 |
13 review(s) available for tetradecanoylphorbol acetate and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
Micronutrient deficiency and neutrophil function in sickle-cell disease.
Topics: Anemia, Sickle Cell; Cytochrome c Group; Hemoglobin SC Disease; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Nutritional Status; Riboflavin; Superoxides; Tetradecanoylphorbol Acetate; Vitamin E; Vitamin E Deficiency | 1990 |
The role of intracellular proteinases in human neutrophil activation.
Topics: Calpain; Cell Compartmentation; Cytoskeletal Proteins; Cytoskeleton; Humans; Macromolecular Substances; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Protein Kinase C; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1989 |
Protein phosphorylation and the respiratory burst.
Topics: Animals; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
The respiratory burst of granulocytes: modulation by inflammatory mediators and its mechanism.
Topics: Animals; Calcium; Colony-Stimulating Factors; Granulocytes; Humans; In Vitro Techniques; Inflammation; Ionomycin; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1988 |
Induction by physiological agents of differentiation of the human leukemia cell line HL-60 to cells with functional characteristics.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Chemotaxis, Leukocyte; Dimethylformamide; Formazans; Humans; Leukemia; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oxidation-Reduction; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Poly-L-arginine and an N-formylated chemotactic peptide act synergistically with lectins and calcium ionophore to induce intense chemiluminescence and superoxide production in human blood leukocytes. Modulation by metabolic inhibitors, sugars, and polyele
Topics: Antimetabolites; Calcimycin; Carbohydrates; Cytochalasin B; Drug Synergism; Electrolytes; Histones; Humans; Inflammation; Lectins; Leukocytes; Ligands; Luminescent Measurements; Luminol; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Polymyxin B; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Exocytosis induced in neutrophils by chemotactic agents and other stimuli.
Topics: Calcimycin; Carrier Proteins; Cell Compartmentation; Chemotactic Factors; Cytoplasmic Granules; Exocytosis; Humans; In Vitro Techniques; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1983 |
Production of active oxygen species by phagocytic leukocytes.
Topics: Amino Acid Sequence; Animals; Cytochrome b Group; Enzyme Activation; Humans; Leukocytes; Macrophages; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phagocytes; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Impaired activation of phospholipase D in polycythaemia vera-implications for the pathogenesis of the disease?
Topics: Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Phospholipase D; Platelet Activating Factor; Polycythemia Vera; Tetradecanoylphorbol Acetate | 1995 |
Circulating neutrophils from patients with ulcerative colitis have a normal respiratory burst.
Topics: Adult; Aged; Blood Cells; Colitis, Ulcerative; Female; Humans; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Respiratory Burst; Tetradecanoylphorbol Acetate | 1995 |
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C5a; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine Release; Humans; Hypersensitivity; Interleukin-3; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nasal Lavage Fluid; Phorbol Esters; Platelet Activating Factor; Prostaglandin D2; Receptors, IgE; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Thapsigargin; Tryptases | 1996 |
Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptor.
Topics: Actins; Adenosine Triphosphate; Blotting, Northern; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Flow Cytometry; HL-60 Cells; Humans; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Purinergic P2; RNA, Messenger; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Manifestations of oxidant stress in uremia.
Topics: Biomarkers; Blood Proteins; C-Reactive Protein; Cardiovascular Diseases; Dose-Response Relationship, Drug; Elapid Venoms; Humans; Hypochlorous Acid; Inflammation; Kidney Failure, Chronic; Macrophage Activation; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phagocytes; Phagocytosis; Renal Dialysis; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Uremia | 2001 |
12 trial(s) available for tetradecanoylphorbol acetate and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
The cardiac glycoside digoxin does not alter the activity of human polymorphonuclear leukocytes in vitro.
Topics: Adult; Blood Bactericidal Activity; Chemotaxis, Leukocyte; Digoxin; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Hemorrhagic tumor necrosis during a pilot trial of tumor necrosis factor-alpha and anti-GD3 ganglioside monoclonal antibody in patients with metastatic melanoma.
Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Female; Gangliosides; Humans; Male; Melanoma; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Necrosis; Neutrophils; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Lysis Syndrome; Tumor Necrosis Factor-alpha | 1994 |
The effects of interleukin-1 therapy on peripheral blood granulocyte function in humans.
Topics: Analysis of Variance; Cell Movement; Chemotaxis, Leukocyte; Dose-Response Relationship, Immunologic; Female; Granulocytes; Humans; Hydrogen Peroxide; Infusions, Intravenous; Interleukin-1; Male; N-Formylmethionine Leucyl-Phenylalanine; Ovarian Neoplasms; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate | 1993 |
In vivo modulation of human neutrophil function by pentoxifylline in patients with septic syndrome.
Topics: Adult; Humans; Infusions, Intravenous; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Respiratory Burst; Sepsis; Tetradecanoylphorbol Acetate | 1995 |
Chemiluminescence responses and chemotaxis of monocytes from patients with early rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chemotaxis, Leukocyte; Female; Humans; Luminescent Measurements; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Rheumatoid Factor; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Dose-dependent enhancements by interferon-gamma on functional responses of neutrophils from chronic granulomatous disease patients.
Topics: Adolescent; Adult; Aspergillus; Child; Dose-Response Relationship, Drug; Double-Blind Method; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Interferon-gamma; Kinetics; Luminescent Measurements; Male; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; NADH Dehydrogenase; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phagocytosis; Phosphoproteins; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
The effects of stem cell factor and granulocyte colony stimulating factor therapy on the activity of the neutrophil NADPH oxidase enzyme system.
Topics: Adult; Granulocyte Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Stem Cell Factor; Tetradecanoylphorbol Acetate | 1998 |
Pentoxifylline decreases neutrophil respiratory bursts in patients with stable angina.
Topics: Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Depression, Chemical; Female; Humans; In Vitro Techniques; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Ketamine attenuates neutrophil activation after cardiopulmonary bypass.
Topics: Aged; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Intravenous; Cardiopulmonary Bypass; Coronary Artery Bypass; Double-Blind Method; Female; Fentanyl; Humans; Ketamine; Leukocyte Count; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Postoperative Complications; Prospective Studies; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis.
Topics: Adalimumab; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antirheumatic Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Biomarkers; CD11b Antigen; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Female; Gene Expression Regulation; Humans; Immunophenotyping; Lectins, C-Type; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2005 |
Preoperative neutrophil response as a predictive marker of clinical outcome following open heart surgery and the impact of leukocyte filtration.
Topics: Aged; CD11b Antigen; Coronary Artery Bypass; Female; Flow Cytometry; Heart Valve Prosthesis Implantation; Humans; Inflammation; L-Selectin; Leukapheresis; Leukocyte Count; Lipopolysaccharides; Male; Membrane Glycoproteins; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Preoperative Period; Tetradecanoylphorbol Acetate; Treatment Outcome | 2010 |
Influence of 4 weeks of bovine colostrum supplementation on neutrophil and mucosal immune responses to prolonged cycling.
Topics: Adult; Animals; Cattle; Cell Degranulation; Colostrum; Dietary Supplements; Double-Blind Method; Exercise; Humans; Immunoglobulin A; Leukocyte Count; Mouth Mucosa; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Primary Cell Culture; Respiratory Burst; Saliva; Tetradecanoylphorbol Acetate; Young Adult | 2015 |
1243 other study(ies) available for tetradecanoylphorbol acetate and n-formylmethionine leucyl-phenylalanine
| Article | Year |
|---|---|
Release of oxygen radicals by articular chondrocytes: a study of luminol-dependent chemiluminescence and hydrogen peroxide secretion.
Topics: Animals; Antioxidants; Azides; Cartilage, Articular; Concanavalin A; Dose-Response Relationship, Drug; Female; Free Radicals; Hydrogen Peroxide; Interferons; Interleukin-1; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Rabbits; Sodium Azide; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
A monoclonal antibody that detects a specific human neutrophil antigen involved in phorbol myristate acetate- and formyl-methionyl-leucyl-phenylalanine-triggered respiratory burst.
Topics: Antibodies, Monoclonal; Antigens, Surface; Calcium; Carrier Proteins; Cell Membrane; Cytosol; Humans; Hydrogen-Ion Concentration; Membrane Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Respiratory Burst; Sodium-Hydrogen Exchangers; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Comparison of influenza A virus and formyl-methionyl-leucyl-phenylalanine activation of the human neutrophil.
Topics: Actins; Calcium; Cell Membrane; Enzyme Activation; Humans; Hydrogen Peroxide; Influenza A virus; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
C-reactive protein inhibits intracellular calcium mobilization and superoxide production by guinea pig alveolar macrophages.
Topics: Animals; C-Reactive Protein; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Activated neutrophils alter contractile properties of the pulmonary artery.
Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contraction; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Artery; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase | 1992 |
Rapid priming of human monocytes by human hematopoietic growth factors: granulocyte-macrophage colony-stimulating factor (CSF), macrophage-CSF, and interleukin-3 selectively enhance superoxide release triggered by receptor-mediated agonists.
Topics: Adult; Cells, Cultured; Concanavalin A; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interferon-gamma; Interleukin-3; Interleukin-4; Macrophage Colony-Stimulating Factor; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Modulation of TNF-alpha-priming and stimulation-dependent superoxide generation in human neutrophils by protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cinnamates; Diglycerides; Genistein; Guinea Pigs; Humans; Isoflavones; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Staurosporine; Sulfides; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Neutrophil function in chronic neutrophilic leukemia: defective respiratory burst in response to phorbol esters.
Topics: Aged; Aged, 80 and over; Female; Humans; Kinetics; Leukemia, Neutrophilic, Chronic; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
FMLP is a potent activator of guinea-pig eosinophils but its activity is dependent on the prior overnight in vitro culture of the cells (facilitation).
Topics: Animals; Cells, Cultured; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Peroxidases; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Effect of staurosporine on fMet-Leu-Phe-stimulated human neutrophils: dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium.
Topics: Alkaloids; Calcium; Diglycerides; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
The effects of the phospholipase A2 inhibitors aristolochic acid and PGBx on A23187-stimulated mobilization of arachidonate in human neutrophils are overcome by diacylglycerol or phorbol ester.
Topics: Arachidonic Acid; Aristolochic Acids; Calcimycin; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenanthrenes; Phosphatidate Phosphatase; Phospholipase D; Phospholipases A; Phospholipases A2; Polymers; Prostaglandins B; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Granulocyte-macrophage colony-stimulating factor-induced protein tyrosine phosphorylation of microtubule-associated protein kinase in human neutrophils.
Topics: Amino Acid Sequence; Antibodies; Blood Proteins; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phosphoproteins; Phosphorylation; Protein Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Scavenger and antioxidant properties of ten synthetic flavones.
Topics: Animals; Antioxidants; Electron Spin Resonance Spectroscopy; Flavonoids; Free Radical Scavengers; Glutathione; Luminescent Measurements; Macrophages, Alveolar; Male; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Rats; Rats, Inbred Strains; Respiratory Burst; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1992 |
Effect of tumor necrosis factor-alpha on the stimulus-coupled responses of neutrophils and their modulation by various inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Calcium; Dose-Response Relationship, Drug; Genistein; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors.
Topics: Diglycerides; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidate Phosphatase; Phosphatidic Acids; Phospholipase D; Phosphorylation; Propranolol; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Alpha-1-antichymotrypsin inhibits the NADPH oxidase-enzyme complex in phorbol ester-stimulated neutrophil membranes.
Topics: alpha 1-Antichymotrypsin; Arachidonic Acid; Calcium; Cell Membrane; Concanavalin A; Humans; In Vitro Techniques; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Neutrophil modulation by Actinobacillus actinomycetemcomitans. II. Phagocytosis and development of respiratory burst.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; Blood Bactericidal Activity; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Superoxide production during refeeding in patients with anorexia nervosa.
Topics: Adolescent; Analysis of Variance; Anorexia Nervosa; Feeding Behavior; Female; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Weight Gain | 1992 |
Differential effects on neutrophil activation of staurosporin and its protein kinase C-selective derivative cgp 41231.
Topics: Alkaloids; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
ONO-4057, a novel, orally active leukotriene B4 antagonist: effects on LTB4-induced neutrophil functions.
Topics: Animals; Calcium; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5a; Cytoplasmic Granules; Guinea Pigs; Humans; Inflammation; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Phenylpropionates; Receptors, Immunologic; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate | 1992 |
Chemiluminescence of human bloodstream monocytes and neutrophils: an unusual oxidant(s) generated by monocytes during the respiratory burst.
Topics: Acridines; Arginine; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Luminescent Measurements; Luminol; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; omega-N-Methylarginine; Oxidants; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Modulation of human monocyte superoxide production by recombinant interleukin-3.
Topics: Cell Adhesion; Cells, Cultured; Humans; Interferon-gamma; Interleukin-3; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Recombinant Proteins; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Low density lipoprotein oxidation by stimulated neutrophils and ferritin.
Topics: Apoproteins; Ascorbic Acid; Catalase; Ceruloplasmin; Ferritins; Humans; Lipid Peroxidation; Lipoproteins, LDL; Methionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Transferrin; Uric Acid | 1992 |
Comparison of doxycycline and a chemically modified tetracycline inhibition of leukocyte functions.
Topics: Cell Adhesion; Cell Degranulation; Doxycycline; Erythrocytes; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetracycline; Tetradecanoylphorbol Acetate | 1992 |
Immunosuppression by human seminal plasma--extracellular organelles (prostasomes) modulate activity of phagocytic cells.
Topics: Cell Adhesion; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immune Tolerance; Latex; Leukocytes; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Organelles; Phagocytosis; Prostate; Receptors, Complement 3b; Receptors, IgG; Semen; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Effect of divalent cations on adhesion of polymorphonuclear leukocytes to matrix molecules in vitro.
Topics: Antigens, CD; Calcium; CD11 Antigens; CD18 Antigens; Cell Adhesion; Humans; In Vitro Techniques; Magnesium; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1992 |
Human neutrophils release their major membrane sialoprotein, leukosialin (CD43), during cell activation.
Topics: Animals; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Aggregation; Cell Communication; Cells, Cultured; Down-Regulation; Humans; Leukosialin; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1992 |
Differentiation of the U-937 promonocytic cell line induced by phorbol myristate acetate or retinoic acid: effect of aurothiomalate.
Topics: Cell Differentiation; Cell Line; gamma-Glutamyltransferase; Gold Sodium Thiomalate; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Phenotype; Superoxides; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin | 1992 |
Altered function and surface marker expression of neutrophils induced by rhG-CSF treatment in severe congenital neutropenia.
Topics: Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Surface; Chemotaxis, Leukocyte; Complement C5a; Fluorescein-5-isothiocyanate; Granulocyte Colony-Stimulating Factor; HLA-DR Antigens; Humans; Immunoglobulin G; In Vitro Techniques; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Recombinant Proteins; Reference Values; Tetradecanoylphorbol Acetate | 1992 |
Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Membrane; Diglycerides; Enzyme Activation; Humans; Isoquinolines; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Naphthalenes; Neutrophils; Piperazines; Polycyclic Compounds; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Charcot-Leyden crystal protein in the degranulation and recovery of activated basophils.
Topics: Antigens, Differentiation, B-Lymphocyte; Basophils; Calcimycin; Cell Degranulation; Fluorescent Antibody Technique; Glycoproteins; Histamine Release; Humans; In Vitro Techniques; Lysophospholipase; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate | 1992 |
Changes in actin state and chemotactic peptide receptor expression in granulocytes during cytokine administration after autologous bone marrow transplantation.
Topics: Actins; Bone Marrow Transplantation; Cytokines; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Macrophage Colony-Stimulating Factor; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1992 |
Thrombospondin receptor expression in human neutrophils coincides with the release of a subpopulation of specific granules.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Sequence; Catalase; CD36 Antigens; Cytochalasin B; Cytoplasmic Granules; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Receptors, Cytoadhesin; Tetradecanoylphorbol Acetate; Transcobalamins | 1992 |
The effect of substance P on neutrophil function in normal and asthmatic subjects.
Topics: Antibody-Dependent Cell Cytotoxicity; Asthma; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Ca(2+)-dependent and Ca(2+)-independent mechanisms modulate whole-cell cationic currents in human neutrophils.
Topics: Adenine Nucleotides; Bucladesine; Calcimycin; Calcium; Cations; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Potassium; Sodium; Tetradecanoylphorbol Acetate | 1992 |
Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue.
Topics: Betahistine; Bucladesine; Calcium; Cations; Cell Differentiation; Cytosol; Glucuronidase; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Ion Channels; Leukemia, Experimental; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Receptors, Histamine H1; Secretory Rate; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella | 1992 |
Insulin, at physiological concentrations, enhances the polymorphonuclear leukocyte chemotactic properties.
Topics: Adult; Chemotaxis, Leukocyte; Female; Humans; In Vitro Techniques; Insulin; Ionophores; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1992 |
Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate.
Topics: Calcimycin; Cells, Cultured; Choline; Diglycerides; Drug Interactions; Ethanol; Glycerophosphates; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Propranolol; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Thrombin promotes actin polymerization in U937 human monocyte-macrophage cells. Analysis of the signalling mechanisms mediating actin polymerization.
Topics: Actins; Alkaloids; Calcium; Cations, Divalent; Cell Line; Chemotaxis, Leukocyte; GTP-Binding Proteins; Humans; Indoles; Ionomycin; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Polymers; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Virulence Factors, Bordetella | 1992 |
Gold complexes and activation of human polymorphonuclear leukocytes. Dissociation of changes in membrane potential and oxidative burst.
Topics: Auranofin; Calcimycin; Cell Survival; Concanavalin A; Drug Interactions; Gold Sodium Thiomalate; Humans; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate | 1992 |
Augmented expression and release of nonspecific cross-reacting antigens (NCAs), members of the CEA family, by human neutrophils during cell activation.
Topics: Antigens, Neoplasm; Antigens, Surface; Calcimycin; Cell Adhesion Molecules; Cell Degranulation; Cell Membrane; Humans; In Vitro Techniques; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1992 |
Signal transduction in monocytes and granulocytes measured by multiparameter flow cytometry.
Topics: Alkaloids; Calcium; Chelating Agents; Cytochalasin B; Egtazic Acid; Flow Cytometry; Fluorescent Dyes; Granulocytes; Humans; Kinetics; Leukocytes, Mononuclear; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Reproducibility of Results; Respiratory Burst; Rhodamines; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Activation of human phagocyte oxidative metabolism by Helicobacter pylori.
Topics: Adult; Free Radicals; Gastritis; Helicobacter pylori; Humans; In Vitro Techniques; Luminescent Measurements; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Phagocytes; Tetradecanoylphorbol Acetate | 1992 |
Phosphatidylinositol hydrolysis by phospholipase A2 and C activities in human peripheral blood neutrophils.
Topics: Arachidonic Acid; Calcimycin; Calcium Chloride; Cell Membrane; Chromatography, Thin Layer; Cytosol; Deoxycholic Acid; Detergents; Edetic Acid; Humans; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Octoxynol; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Polyethylene Glycols; Stearic Acids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
An ultrastructural analysis of tumor-promoting phorbol diester-induced degranulation of human basophils.
Topics: Basophils; Cell Degranulation; Histamine; Humans; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
[The effect of inhibitors of glucose utilization on the chemiluminescence and fluorescence of murine peritoneal macrophages].
Topics: Animals; Depression, Chemical; Fluorescence; Glucose; Glycolysis; Luminescent Measurements; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Ligand dependent release of activated neutrophil collagenase--a role for surface bound IgG in the degradation of articular collagens.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Collagenases; Humans; Immunoglobulin G; Ligands; Matrix Metalloproteinase 8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Antigen, B-Cell; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Increased expression of adhesion proteins (MAC-1) and altered metabolic response in human leukocytes exposed to surfactant in vitro.
Topics: Adolescent; Adult; Aged; Flow Cytometry; Granulocytes; Humans; In Vitro Techniques; Luminescent Measurements; Macrophage-1 Antigen; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pulmonary Surfactants; Tetradecanoylphorbol Acetate | 1992 |
Priming of human polymorphonuclear leukocytes with granulocyte-macrophage colony-stimulating factor involves protein kinase C rather than enhanced calcium mobilisation.
Topics: Alkaloids; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcium; Cations, Divalent; Chromatography, High Pressure Liquid; Cycloheximide; Dactinomycin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Oxidative metabolism of polymorphonuclear leukocytes (PMN) in patients with IgA nephropathy.
Topics: Adult; Female; Glomerulonephritis, IGA; Humans; Hydrogen Peroxide; Immunoglobulin G; In Vitro Techniques; Kidney Glomerulus; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Granulocyte-macrophage colony-stimulating factor induces a staurosporine inhibitable tyrosine phosphorylation of unique neutrophil proteins.
Topics: Alkaloids; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Development of a technique for monitoring the contamination of human semen samples with leukocytes.
Topics: Cell Fractionation; Cell Separation; Germ Cells; Humans; Leukocytes; Luminescent Measurements; Magnetics; Male; Methods; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; Semen; Tetradecanoylphorbol Acetate | 1992 |
Regulation of phosphatidic acid phosphohydrolase activity during stimulation of human polymorphonuclear leukocytes.
Topics: Calcimycin; Gene Expression Regulation, Enzymologic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidate Phosphatase; Signal Transduction; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Imaging neutrophil activation: analysis of the translocation and utilization of NAD(P)H-associated autofluorescence during antibody-dependent target oxidation.
Topics: Antibodies; Enzyme Activation; Humans; Image Processing, Computer-Assisted; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Phagocytosis; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Calcium rather than protein kinase C is the major factor to activate phospholipase D in FMLP-stimulated rabbit peritoneal neutrophils. Possible involvement of calmodulin/myosin L chain kinase pathway.
Topics: Animals; Arachidonic Acid; Calcium; Calmodulin; Enzyme Activation; In Vitro Techniques; Myosin-Light-Chain Kinase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Rabbits; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Differentiation of human peripheral blood monocytes to macrophages is associated with changes in the cellular respiratory burst activity.
Topics: Adult; Cell Differentiation; Humans; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Respiratory Burst; Tetradecanoylphorbol Acetate | 1992 |
Paradoxical stimulation and inhibition by protein kinase C modulating agents of lipopolysaccharide evoked production of tumour necrosis factor in human monocytes.
Topics: Cells, Cultured; Cytotoxicity, Immunologic; Humans; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1992 |
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan | 1992 |
The activation of the electrogenic NADPH oxidase.
Topics: Alkaloids; Cell Membrane; Enzyme Activation; Humans; Membrane Potentials; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
A monoclonal antibody against peripheral benzodiazepine receptor activities the human neutrophil NADPH-oxidase.
Topics: Antibodies, Monoclonal; Antigen-Antibody Complex; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Luminescent Measurements; Membrane Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Receptors, GABA-A; Tetradecanoylphorbol Acetate | 1991 |
Disassociation of the macrophage-maturational effects of vitamin D from respiratory burst priming.
Topics: Antineoplastic Agents; Calcitriol; Calcium; Cell Differentiation; Cell Line; Cytoplasm; Humans; Leukemia, Promyelocytic, Acute; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Calcitriol; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Steroid; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Effect of 22-32 carbon n-3 polyunsaturated fatty acids on superoxide production in human neutrophils: synergism of docosahexaenoic acid with f-met-leu-phe and phorbol ester.
Topics: Calmodulin; Cells, Cultured; Cytochalasin B; Docosahexaenoic Acids; Drug Synergism; Fatty Acids; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
The neutrophil respiratory burst. Responses to fatty acids, N-formylmethionylleucylphenylalanine and phorbol ester suggest divergent signalling mechanisms.
Topics: Calcium; Ethanol; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phospholipase D; Phospholipids; Propranolol; Signal Transduction; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Chronic treatment with P2-purinergic receptor agonists induces phenotypic modulation of the HL-60 and U937 human myelogenous leukemia cell lines.
Topics: Actins; Adenosine; Adenosine Triphosphate; Calcium; Cell Differentiation; Cell Division; Cell Line; Genes, myc; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Phenotype; Receptors, Purinergic; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1991 |
Membrane potential in human myeloid leukemia cell line ML-1: responsiveness of granulocytic and monocytic differentiated cells.
Topics: Benzothiazoles; Carbocyanines; Cell Differentiation; Fluorescence; Granulocytes; Humans; Kinetics; Leukemia, Myeloid; Membrane Potentials; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Valinomycin | 1991 |
Interferon-gamma enhances superoxide production by HL-60 cells stimulated with multiple agonists.
Topics: Antigens, Surface; Cell Differentiation; Humans; Interferon-gamma; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Biosynthesis; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Neutrophil beta-adrenergic receptor responses are potentiated by acute exposure to phorbol ester without changes in receptor distribution or coupling.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Humans; Isoproterenol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1991 |
Concentration-dependent regulatory effects of prostaglandin E1 on human neutrophil function in vitro.
Topics: Alprostadil; Chemotaxis, Leukocyte; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Luminol chemiluminescence and active oxygen generation by activated neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Azides; Cytochalasin B; Ferric Compounds; Free Radical Scavengers; Guinea Pigs; Hydroxides; Hydroxyl Radical; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxygen; Peroxidase; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Uric Acid; Zymosan | 1991 |
Isolation of human salivary polymorphonuclear leukocytes and their stimulation-coupled responses.
Topics: Annexins; Arachidonic Acid; Arachidonic Acids; Azides; Calcium; Calcium-Binding Proteins; Cell Membrane; Cell Separation; Humans; Kinetics; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Peroxidase; Saliva; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Inhibition by nilvadipine of ischemic and carrageenan paw edema as well as of superoxide radical production from neutrophils and xanthine oxidase.
Topics: Animals; Calcimycin; Carrageenan; Edema; Free Radicals; Ischemia; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred Strains; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1991 |
Priming action of inositol hexakisphosphate (InsP6) on the stimulated respiratory burst in human neutrophils.
Topics: Calcium; Humans; In Vitro Techniques; Inositol Phosphates; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Phytic Acid; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Differentiation-linked activation of the respiratory burst in a monocytic cell line (U937) via Fc gamma RII. A study of activation pathways and their regulation.
Topics: Antigens, Differentiation; Arachidonic Acid; Calcium; Cell Differentiation; Cyclic AMP; Eicosanoids; Gene Expression; Humans; In Vitro Techniques; Interferon-gamma; Isoenzymes; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Respiratory Burst; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils.
Topics: Analysis of Variance; Cell Fractionation; Diglycerides; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Tumor necrosis factor-alpha primes pulmonary hemodynamic response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
Topics: Animals; Antioxidants; Drug Synergism; Guinea Pigs; Hemodynamics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Organ Size; Peroxidase; Platelet Activating Factor; Pulmonary Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1991 |
Differential effects of propranolol on responses to receptor-dependent and receptor-independent stimuli in human neutrophils.
Topics: Calcium; Humans; In Vitro Techniques; Ionomycin; Isomerism; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Platelet Activating Factor; Propranolol; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Superoxide anion production and expression of cytochrome b 558 by neutrophils are impaired in some patients with myelodysplastic syndrome.
Topics: Adult; Aged; Aged, 80 and over; Cytochrome b Group; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Bovine lens capsule basement membrane collagen exerts a negative priming on polymorphonuclear neutrophils.
Topics: Animals; Basement Membrane; Cattle; Cell Adhesion; Collagen; Humans; In Vitro Techniques; Kinetics; Lens, Crystalline; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The prostaglandin paradox: additive inhibition of neutrophil function by aspirin-like drugs and the prostaglandin E1 analog misoprostol.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Calcium; Cell Aggregation; Cyclic AMP; Depression, Chemical; Drug Synergism; Glucuronidase; Humans; Indomethacin; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins; Sodium Salicylate; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Neutrophil function in polycythemia vera.
Topics: Humans; Leukotriene B4; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polycythemia Vera; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Scavenging of superoxide anion by phosphorylethanolamine: studies in human neutrophils and in a cell free system.
Topics: Cell-Free System; Dianisidine; Ethanolamines; Free Radical Scavengers; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phosphorylcholine; Photochemistry; Respiratory Burst; Riboflavin; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Effect of recombinant human granulocyte/macrophage colony-stimulating factor on neutrophil superoxide production.
Topics: Adult; Alkaloids; Cytochalasin B; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Rolipram; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) primes human neutrophils for enhanced phosphatidylcholine breakdown by phospholipase D.
Topics: Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Effect of Ca-panthotenate on human granulocyte oxidative metabolism.
Topics: Cell Degranulation; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Pantothenic Acid; Peroxidase; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes.
Topics: Calcimycin; Cyclooxygenase Inhibitors; Cytoplasmic Granules; Diterpenes; Humans; Lipoxygenase Inhibitors; Luminescent Measurements; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Retinyl Esters; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A; Zymosan | 1991 |
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.
Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1991 |
Ethanol impairs certain aspects of neutrophil adhesion in vitro: comparisons with inhibition of expression of the CD18 antigen.
Topics: Antigens, CD; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Ethanol; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Effects of azelastine on superoxide anion generation from gamma interferon treated human monoblast cell line U937 measured by chemiluminescence method.
Topics: Cell Adhesion; Cell Line; Histamine H2 Antagonists; Humans; Imidazoles; Interferon-gamma; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Phthalazines; Pyrazines; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Tyrosine-specific protein phosphorylation during activation of human neutrophils.
Topics: Blotting, Western; Calcimycin; Cytosol; Humans; In Vitro Techniques; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Protein tyrosine phosphorylation in rabbit peritoneal neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcimycin; Calcium; Immunoblotting; Isoquinolines; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Rabbits; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Signal transduction events in human basophils. A comparative study of the role of protein kinase C in basophils activated by anti-IgE antibody and formyl-methionyl-leucyl-phenylalanine.
Topics: Alkaloids; Antibodies, Anti-Idiotypic; Basophils; Calcium; Cell Degranulation; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptor Aggregation; Signal Transduction; Sphingosine; SRS-A; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Differential modulation by N4, 2'-O-dibutyryl cytidine 3':5'-cyclic monophosphate of neutrophil activation.
Topics: Butyrates; Calcimycin; Calcium; Cyclic CMP; Growth Substances; Hexachlorocyclohexane; Humans; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1991 |
In vitro functions of neutrophils induced by treatment with rhG-CSF in severe congenital neutropenia.
Topics: Blood Bactericidal Activity; Cell Nucleus; Chemotaxis, Leukocyte; Cytoplasm; Eosinophils; Free Radicals; Granulocyte Colony-Stimulating Factor; Humans; Leukocyte Count; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Oxygen; Phagocytes; Phagocytosis; Recombinant Proteins; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Metabolism of substance P and bradykinin by human neutrophils.
Topics: Amino Acid Sequence; Bradykinin; Cathepsin G; Cathepsins; Cell Membrane; Cytochalasin B; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neprilysin; Neutrophils; Serine Endopeptidases; Subcellular Fractions; Substance P; Tetradecanoylphorbol Acetate | 1991 |
Differential activation of human basophils by anti-IgE and formyl-methionyl-leucyl-phenylalanine. Indications for protein kinase C-dependent and -independent activation pathways.
Topics: Alkaloids; Androstadienes; Antibodies, Anti-Idiotypic; Basophils; Cells, Cultured; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 1991 |
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Humans; In Vitro Techniques; Integrins; Lipid Bilayers; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; P-Selectin; Platelet Membrane Glycoproteins; Stress, Mechanical; Tetradecanoylphorbol Acetate | 1991 |
Eosinophil activation on biologic surfaces. Production of O2- in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells.
Topics: Endothelium, Vascular; Eosinophils; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation.
Topics: Anti-Bacterial Agents; Calcimycin; Cycloheximide; Cyclosporins; Dactinomycin; Humans; Immune Tolerance; Ionomycin; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polyenes; Signal Transduction; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate | 1991 |
Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Antigens, Differentiation; Calcimycin; Cell Degranulation; Cholera Toxin; Cyclic AMP; Eosinophil-Derived Neurotoxin; Eosinophils; GTP-Binding Proteins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neurotoxins; Pertussis Toxin; Phosphatidylinositols; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Ribonucleases; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Down-regulation by tumor necrosis factor-alpha of neutrophil cell surface expression of the sialophorin CD43 and the hyaluronate receptor CD44 through a proteolytic mechanism.
Topics: Antigens, CD; Calcimycin; Cell Adhesion Molecules; Down-Regulation; Flow Cytometry; Histocompatibility Antigens; Humans; L-Selectin; Leukocyte Common Antigens; Leukosialin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Precipitin Tests; Receptors, Lymphocyte Homing; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
The effect of interleukin-4 on the macrophage respiratory burst is species dependent.
Topics: Animals; Calcimycin; Cells, Cultured; Cytokines; Humans; Interferon-gamma; Interleukin-4; Kinetics; Lipopolysaccharides; Macrophages; Mice; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Receptor class desensitization of leukocyte chemoattractant receptors.
Topics: Adenoviruses, Human; Base Sequence; Calcium; Carbachol; Cell Line; Cell Line, Transformed; Cloning, Molecular; Complement C5a; Cytosol; Humans; Kidney; Kinetics; Leukocytes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Norepinephrine; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1991 |
A photometric assay for hydrogen peroxide production by polymorphonuclear leucocytes.
Topics: Arachidonic Acid; Glutathione Peroxidase; Glutathione Reductase; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Photometry; Tetradecanoylphorbol Acetate | 1991 |
The fate of human polymorphonuclear leukocyte aminopeptidases upon cell stimulation with phagocytic and chemical stimuli.
Topics: Aminopeptidases; Cell Degranulation; Cell Division; Humans; Isoelectric Focusing; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Effect of tumour necrosis factor alpha in vivo on human granulocyte oxidative metabolism.
Topics: Acridines; Amino Acid Sequence; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Luminescent Measurements; Lymphotoxin-alpha; Melanoma; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Platelet activating factor-induced pulmonary accumulation of 111Indium-oxine labelled neutrophils in anesthetized guinea pigs.
Topics: Analysis of Variance; Anesthesia, General; Animals; Guinea Pigs; In Vitro Techniques; Indium Radioisotopes; Kinetics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organometallic Compounds; Oxyquinoline; Platelet Activating Factor; Radioisotope Dilution Technique; Tetradecanoylphorbol Acetate | 1991 |
Selective incorporation of 15-HETE in phosphatidylinositol: agonist-induced deacylation and transformation of stored HETEs by human neutrophils.
Topics: Acylation; Calcimycin; Cell Aggregation; Esterification; Humans; Hydroxyeicosatetraenoic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1991 |
Beta-thromboglobulin and polymorphonuclear leukocytes activation. (Effects on chemiluminescence, release of membrane bound calcium, NADPH-oxidase activity and membrane fluidity).
Topics: beta-Thromboglobulin; Blood Platelets; Calcium; Cell Membrane Permeability; Fluorescence Polarization; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Opsonin Proteins; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Platelets and ATP prime neutrophils for enhanced O2- generation at low concentrations but inhibit O2- generation at high concentrations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Hydrogen peroxide modulation of the respiratory burst of human neutrophils.
Topics: Catalase; Hydrogen Peroxide; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
GM-1, a clone of the monoblastic phagocyte U937 that expresses a large respiratory burst capacity upon activation with interferon-gamma.
Topics: Antigens, CD; Cytochrome b Group; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Recombinant Proteins; Spectrum Analysis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1991 |
Neutrophils isolated from the synovial fluid of patients with rheumatoid arthritis: priming and activation in vivo.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cytochalasin B; Humans; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Peroxidase; Stimulation, Chemical; Synovial Fluid; Tetradecanoylphorbol Acetate | 1991 |
Activation of human neutrophils by Mycobacterium tuberculosis-derived sulfolipid-1.
Topics: Calcium; Cells, Cultured; Diglycerides; Glycolipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Pertussis Toxin; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors; Virulence Factors, Bordetella | 1991 |
Superoxide responses to formyl-methionyl-leucyl-phenylalanine in primed neutrophils. Role of intracellular and extracellular calcium.
Topics: Calcium; Cytoplasm; Extracellular Space; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Influence of lactoferrin on the function of human polymorphonuclear leukocytes and monocytes.
Topics: Cell Aggregation; Cells, Cultured; Chemotaxis, Leukocyte; Colostrum; Cytoplasmic Granules; Female; Humans; Kinetics; Lactoferrin; Leukocytes, Mononuclear; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pregnancy; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
The protein kinase C inhibitor, K252a, inhibits superoxide production in human neutrophils activated by both PIP2-dependent and -independent mechanisms.
Topics: Calcium; Carbazoles; Concanavalin A; Humans; Indole Alkaloids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Protein kinase C-dependent and -independent activation of the NADPH oxidase of human neutrophils.
Topics: Alkaloids; Aminoquinolines; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Protein Kinase C; Recombinant Proteins; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Passive smoking by humans sensitizes circulating neutrophils.
Topics: Adult; Chemotaxis, Leukocyte; Cotinine; Cytochalasin B; Female; Humans; Leukocyte Count; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Smoking; Tetradecanoylphorbol Acetate; Tobacco Smoke Pollution; Tumor Necrosis Factor-alpha | 1991 |
Defective protein kinase C-mediated actions in cystic fibrosis neutrophils.
Topics: Cystic Fibrosis; Diglycerides; Enzyme Activation; Exocytosis; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1991 |
Purine catabolism in polymorphonuclear neutrophils. Phorbol myristate acetate-induced accumulation of adenosine owing to inactivation of extracellularly released adenosine deaminase.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Biological Transport; Cells, Cultured; Deoxyglucose; Humans; Hypoxanthine; Hypoxanthines; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Purine-Nucleoside Phosphorylase; Tetradecanoylphorbol Acetate | 1991 |
Interferon-gamma enhances PAF-acether production by stimulated human polymorphonuclear leucocytes.
Topics: Antigen-Antibody Complex; Cells, Cultured; Humans; Interferon-gamma; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1991 |
Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil.
Topics: Androstadienes; Androstenes; Anti-Inflammatory Agents, Non-Steroidal; Diglycerides; Female; GTP-Binding Proteins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Second Messenger Systems; Tetradecanoylphorbol Acetate; Type C Phospholipases; Wortmannin | 1991 |
Oxidative metabolism of circulating granulocytes in adult respiratory distress syndrome.
Topics: Acridines; Female; Granulocytes; Humans; Luminescent Measurements; Luminol; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Chemotactic peptide stimulation of arachidonic acid release in HL60 cells, an interaction between G protein and phospholipase C mediated signal transduction.
Topics: Adenosine Triphosphate; Arachidonic Acid; Calcium; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Neomycin; Phospholipases A; Phospholipases A2; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1991 |
Inactivation of recombinant human tumor necrosis factor-alpha by proteolytic enzymes released from stimulated human neutrophils.
Topics: Catalase; Cell Degranulation; Cytochalasin B; Endopeptidases; Free Radicals; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Recombinant Proteins; Respiratory Burst; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Further studies of the defective stimulus-response coupling for the oxidative burst in neutrophils in polycythemia vera.
Topics: Aged; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Interferon-alpha; Lactoferrin; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polycythemia Vera; Reference Values; Respiratory Burst; Tetradecanoylphorbol Acetate | 1991 |
Ionizing radiation at low doses induces inflammatory reactions in human blood.
Topics: Arachidonic Acid; Blood; Blood Cells; Calcimycin; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Humans; Inflammation; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Radiation Dosage; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate | 1991 |
Human fibroblasts release low amounts of reactive oxygen species in response to the potent phagocyte stimulants, serum-treated zymosan, N-formyl-methionyl-leucyl-phenylalanine, leukotriene B4 or 12-O-tetradecanoylphorbol 13-acetate.
Topics: Electron Spin Resonance Spectroscopy; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Leukotriene B4; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oxidation-Reduction; Oxygen; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Leukotriene D4 induced calcium changes in U937 cells may utilize mechanisms additional to inositol phosphate production that are pertussis toxin insensitive but are blocked by phorbol myristate acetate.
Topics: Calcium; Cell Line; Humans; Inositol Phosphates; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; SRS-A; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Stimulation of a histone H4 protein kinase in Triton X-100 lysates of rabbit peritoneal neutrophils pretreated with chemotactic factors: lack of requirements of calcium mobilization and protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cells, Cultured; Detergents; Egtazic Acid; Enzyme Activation; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Octoxynol; Peritoneal Cavity; Piperazines; Polyethylene Glycols; Protamine Kinase; Protein Kinase C; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Priming of neutrophil oxidative responses by platelet-activating factor.
Topics: Adult; Cytochalasin B; Drug Synergism; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Stimulus- and cumulative dose-dependent inhibition of O2- production by polymorphonuclear leukocytes of patients receiving corticosteroids.
Topics: Adult; Chemotaxis, Leukocyte; Concanavalin A; Cytochalasin D; Dose-Response Relationship, Drug; Female; Humans; Immune System; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prednisolone; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Neutrophil defect associated with hairy cell leukemia.
Topics: Cell Movement; Chemotaxis, Leukocyte; Cytotoxicity, Immunologic; Humans; Leukemia, Hairy Cell; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Constitutive and induced phosphorylation of the alpha- and beta-chains of the CD11/CD18 leukocyte integrin family. Relationship to adhesion-dependent functions.
Topics: Amino Acid Sequence; Antigens, CD; Antigens, Differentiation; Antigens, Surface; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Integrins; Leukocytes, Mononuclear; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate | 1990 |
Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation.
Topics: Alkaloids; Antibodies, Monoclonal; Antigens, CD; CD18 Antigens; Cell Aggregation; Cell Degranulation; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Humans; In Vitro Techniques; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Receptors, Leukocyte-Adhesion; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Evidence that a receptor-operated event on the neutrophil mediates neutrophil accumulation in vivo. Pretreatment of 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Degranulation; Complement C5a; Inflammation; Interleukin-1; Interleukin-8; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Rabbits; Receptors, Leukocyte-Adhesion; Recombinant Proteins; Skin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Zymosan | 1990 |
Inhibitory effects of azelastine on superoxide anion generation from activated inflammatory cells measured by a simple chemiluminescence method.
Topics: Animals; Cytochalasin B; Eosinophils; Histamine H1 Antagonists; Humans; In Vitro Techniques; Inflammation; Luminescent Measurements; Male; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; p-Methoxy-N-methylphenethylamine; Phthalazines; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Signal transduction and the regulation of actin conformation during myeloid maturation: studies in HL60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Bryostatins; Calcium; Cell Differentiation; Dimethyl Sulfoxide; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Lactones; Macrolides; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Effects of zymosan-activated human granulocytes on isolated human airways.
Topics: Adult; Aged; Aged, 80 and over; Autonomic Fibers, Postganglionic; Bronchoconstriction; Calcimycin; Concanavalin A; Electric Stimulation; Female; Granulocytes; Humans; Hypersensitivity, Immediate; In Vitro Techniques; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
The role of adhesive interactions and extracellular matrix fibronectin from human polymorphonuclear leukocytes in the respiratory burst.
Topics: Adult; Cell Adhesion; Disulfides; Extracellular Matrix; Fibronectins; Garlic; Herb-Drug Interactions; Humans; In Vitro Techniques; Kinetics; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Plant Extracts; Plants, Medicinal; Receptors, Immunologic; Sulfoxides; Tetradecanoylphorbol Acetate | 1991 |
Neutrophil erythrotoxicity induced by phorbol myristate acetate: mechanisms involved in neutrophil activation.
Topics: Antigen-Antibody Complex; Calcimycin; Catalase; Cell Adhesion; Cell Survival; Chemotaxis; Dose-Response Relationship, Drug; Erythrocytes; Humans; Immunity, Cellular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
In vitro model of intestinal crypt abscess. A novel neutrophil-derived secretagogue activity.
Topics: Abscess; Bumetanide; Cell Membrane Permeability; Electric Conductivity; Humans; Hydrogen Peroxide; In Vitro Techniques; Intestinal Diseases; Lipopolysaccharides; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty a
Topics: Acyl Coenzyme A; Amino Acid Sequence; Antibodies, Monoclonal; Calcium; Cell Compartmentation; Coenzyme A; Diglycerides; Fatty Acids, Nonesterified; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phosphatidylserines; Phosphoproteins; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Alterations in tyrosine protein kinase activities upon activation of human neutrophils.
Topics: Autoradiography; Cell Separation; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The involvement of calcium and protein kinase C in modulating agonist-stimulated chemotaxis of human neutrophils.
Topics: Calcium; Chemotaxis, Leukocyte; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nickel; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effects of polyene antibiotics on the activation of human polymorphonuclear leukocytes.
Topics: Amphotericin B; Calcimycin; Dose-Response Relationship, Drug; Free Radicals; Humans; Kinetics; Latex; Luminescent Measurements; Lymphocyte Activation; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Potassium; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.
Topics: Alkaloids; Calcium; Complement C5a; Eosinophils; Exocytosis; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Peroxidases; Pertussis Toxin; Platelet Activating Factor; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Human eosinophils are more toxic than neutrophils in antibody-independent killing.
Topics: Antibody-Dependent Cell Cytotoxicity; Child; Child, Preschool; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Granulomatous Disease, Chronic; Humans; Infant; Killer Cells, Natural; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Substrate dependence of human neutrophil protein kinase C.
Topics: Histones; Humans; Myosins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate; Troponin | 1991 |
Source and role of diacylglycerol formed during phagocytosis of opsonized yeast particles and associated respiratory burst in human neutrophils.
Topics: Alkaloids; Complement C3b; Diglycerides; Humans; Immunoglobulin G; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytosis; Phospholipase D; Phospholipids; Propranolol; Protein Kinase C; Saccharomyces cerevisiae; Staurosporine; Tetradecanoylphorbol Acetate; Tritium | 1991 |
The ability of polymorphonuclear leukocyte priming agents to overcome influenza A virus-induced cell dysfunction.
Topics: Diglycerides; Granulocyte-Macrophage Colony-Stimulating Factor; Guanosine Triphosphate; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Humans; In Vitro Techniques; Influenza A virus; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Tetradecanoylphorbol Acetate; Viral Envelope Proteins | 1991 |
Activation of human neutrophil phospholipase D by three separable mechanisms.
Topics: Androstadienes; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Egtazic Acid; Enzyme Activation; Glycerophospholipids; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate; Wortmannin | 1990 |
In vivo and in vitro assessment of porcine neutrophil activation responses to chemoattractants: flow cytometric evidence for the selective absence of formyl peptide receptors.
Topics: Animals; Calcimycin; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Complement C5a; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Ligands; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Swine; Tetradecanoylphorbol Acetate; Thiocyanates; Zymosan | 1990 |
A role for calcium and protein kinase C in agonist-stimulated adhesion of human neutrophils.
Topics: Benzofurans; Calcium; Cell Adhesion; Egtazic Acid; Enzyme Activation; Fluorescent Dyes; Fura-2; Humans; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Release of a neutrophil-derived vasoconstrictor agent which augments platelet-induced contractions of blood vessels in vitro.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Calcimycin; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Molecular Weight; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Serotonin; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1990 |
Differential effects of lithocholate on rat neutrophil activation.
Topics: Animals; Calcimycin; Calcium; L-Lactate Dehydrogenase; Lithocholic Acid; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxides; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Human neutrophil stimulation by influenza virus: relationship of cytoplasmic pH changes to cell activation.
Topics: Calcium; Cholera Toxin; Cytoplasm; Egtazic Acid; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Influenza A virus; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Mechanism of N-formyl-methionyl-leucyl-phenylalanine- and platelet-activating factor-induced arachidonic acid release in guinea pig alveolar macrophages: involvement of a GTP-binding protein and role of protein kinase A and protein kinase C.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Down-Regulation; GTP-Binding Proteins; Guinea Pigs; Isoquinolines; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Alveoli; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Migration of dog polymorphonuclear neutrophilic leukocytes to formylated peptides.
Topics: Animals; Chemotaxis, Leukocyte; Dogs; Drug Synergism; Escherichia coli; Female; GTP-Binding Proteins; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Thromboxane release by lymphokine-differentiated U937 human monocytic cells: response to platelet-activating factor (PAF) and chemotactic peptide (FMLP) but not to low affinity IGE-receptor (Fc epsilon RII/CD23) occupation.
Topics: Antibodies, Anti-Idiotypic; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Drug Synergism; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukemia, Monocytic, Acute; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Binding; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Auranofin modulated cytoplasmic free calcium in neutrophils by mobilizing intracellular calcium and inhibiting protein kinase.
Topics: Auranofin; Ca(2+) Mg(2+)-ATPase; Calcium; Cell Compartmentation; Cytoplasm; Dose-Response Relationship, Drug; Fluorescence; Gold Sodium Thiomalate; Homeostasis; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Chemotactic peptide enhancement of phorbol ester-induced protein kinase C activity in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cytochalasin B; Diglycerides; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Pertussis toxin inhibits the FMLP-induced membrane association of protein kinase C in human neutrophils.
Topics: Cell Membrane; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Superoxide production by wound neutrophils. Evidence for increased activity of the NADPH oxidase.
Topics: Animals; Blood; Cytochrome b Group; Dose-Response Relationship, Drug; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Rabbits; Skin; Spectrum Analysis; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Characterization of influenza A virus activation of the human neutrophil.
Topics: Calcium; Cholera Toxin; GTP-Binding Proteins; Humans; Hydrogen Peroxide; In Vitro Techniques; Influenza A virus; Inositol Phosphates; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Subcellular distribution and mobilization of MAC-1 (CD11b/CD18) in neonatal neutrophils.
Topics: Antigens, Differentiation; Biological Transport; Cell Compartmentation; Chemotaxis, Leukocyte; Cytoplasmic Granules; Exocytosis; Gelatinases; Humans; Infant, Newborn; Lactoferrin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepsin A; Receptors, Leukocyte-Adhesion; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transcobalamins | 1990 |
Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine.
Topics: Blood Physiological Phenomena; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Chemoattractants stimulate phosphatidylinositol-4-phosphate kinase in human polymorphonuclear leukocytes.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenosine Triphosphate; Amino Acid Sequence; Cell Membrane; Chemotactic Factors; Cytochalasin B; Humans; Kinetics; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1990 |
Activation of neutrophils by cachectin/tumor necrosis factor: priming of N-formyl-methionyl-leucyl-phenylalanine-induced oxidative responsiveness via receptor mobilization without degranulation.
Topics: Adult; Cell Degranulation; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Stimulus-specific effects of pentoxifylline on neutrophil CR3 expression, degranulation, and superoxide production.
Topics: Adenosine; Cell Degranulation; Cytoskeleton; Glucans; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Receptors, Complement; Receptors, Complement 3b; Superoxides; Tetradecanoylphorbol Acetate; Theobromine | 1990 |
Action sites of antiallergic drugs on human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Histamine Antagonists; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Evaluation of synthetic sphingosine, lysosphingolipids and glycosphingolipids as inhibitors of functional responses of human neutrophils.
Topics: Antigens, CD; Calcimycin; Cell Aggregation; Cerebrosides; Galactosylceramides; Globosides; Glycolipids; Glycosphingolipids; Humans; Lactosylceramides; Leukotriene B4; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Psychosine; Sphingolipids; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Trihexosylceramides | 1990 |
Endothelial cells inhibit receptor-mediated superoxide anion production by human polymorphonuclear leukocytes via a soluble inhibitor.
Topics: Adenosine; Animals; Arachidonic Acids; Cattle; Cell Adhesion; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Artery; Solubility; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Zymosan | 1990 |
Reversible drug effects on the metabolic activation of polymorphonuclear leukocytes.
Topics: Amines; Animals; Arachidonic Acid; Arachidonic Acids; Benzenesulfonates; Chlorpromazine; Guinea Pigs; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phthalazines; Pyridazines; Spectrophotometry; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.
Topics: Biological Transport; Cell Membrane; Cytosol; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Temperature; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of active oxygen generation in guinea-pig neutrophils by biscoclaurine alkaloids.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Benzylisoquinolines; Free Radicals; Guinea Pigs; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Induction of the oxidative response and of concanavalin A-binding capacity in maturing human U937 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Concanavalin A; Humans; Kinetics; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Concanavalin A; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan | 1990 |
GM-CSF: receptor structure and transmembrane signaling.
Topics: Cell Membrane; Colony-Stimulating Factors; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Platelet Activating Factor; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Sepharose; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Dietary linoleate supplementation modulates formyl-peptide receptor expression and functional responses of rat neutrophils.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate 5-Lipoxygenase; Calcimycin; Calcium; Dietary Fats; Ionomycin; Leukotriene B4; Linoleic Acid; Linoleic Acids; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Rats; Rats, Inbred Strains; Receptors, Formyl Peptide; Receptors, Immunologic; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Inhibition of human polymorphonuclear leukocyte respiratory burst activity and aggregation by 6-ketocholestanol.
Topics: Cell Aggregation; Cell Survival; Cholesterol; Cytochrome c Group; Humans; Hydrogen Peroxide; Ketocholesterols; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Human immunoglobulin G potentiates superoxide production induced by chemotactic peptides and causes degranulation in isolated human neutrophils.
Topics: Calcium; Cathepsin G; Cathepsins; Cell Degranulation; Concanavalin A; Drug Synergism; Humans; Immunoglobulin G; In Vitro Techniques; Microbial Collagenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Serine Endopeptidases; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process.
Topics: Arachidonic Acids; Calmodulin; Chlorpromazine; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Free Radicals; gamma-Linolenic Acid; Humans; Leukocytes; Linolenic Acids; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1990 |
Neutrophil elastase activity and superoxide production are diminished in neutrophils of alcoholics.
Topics: Adult; Alcoholism; Ethanol; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Pulmonary Emphysema; Stem Cells; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Temporal adaptation of human neutrophil metabolic responsiveness to the peptide formylmethionyl-leucyl phenylalanine: a comparison between human neutrophils and granule-depleted neutrophil cytoplasts.
Topics: Cell Degranulation; Cell Survival; Cytoplasmic Granules; Humans; Hydrogen Peroxide; Ligands; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558.
Topics: Amino Acid Sequence; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cytochrome b Group; Cytosol; Enzyme Activation; Humans; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oligopeptides; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Cocaine and its derivatives blunt neutrophil functions without influencing phosphorylation of a 47-kilodalton component of the reduced nicotinamide-adenine dinucleotide phosphate oxidase.
Topics: Anesthetics, Local; Calcimycin; Cell Aggregation; Cell Degranulation; Cocaine; Glucuronidase; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Receptors, Complement; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Up-Regulation | 1990 |
Vitamin C and cellular immune functions. Protection against hypochlorous acid-mediated inactivation of glyceraldehyde-3-phosphate dehydrogenase and ATP generation in human leukocytes as a possible mechanism of ascorbate-mediated immunostimulation.
Topics: Adenosine Triphosphate; Antioxidants; Ascorbic Acid; Glucose; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunity, Cellular; Immunization; Lymphocyte Activation; Mitogens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfhydryl Compounds; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Mg.ATP primes superoxide-generating responses in electropermeabilized neutrophils.
Topics: Adenosine Triphosphate; Animals; Cell Membrane Permeability; Electricity; Enzyme Induction; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Soluble Fc gamma receptor III in human plasma originates from release by neutrophils.
Topics: Antibodies, Monoclonal; Antigens, Differentiation; Humans; Killer Cells, Natural; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Precipitin Tests; Radioimmunoassay; Receptors, Fc; Receptors, IgG; Solubility; Tetradecanoylphorbol Acetate | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
The effect of putative protein kinase C inhibitors, K252a and staurosporine, on the human neutrophil respiratory burst activated by both receptor stimulation and post-receptor mechanisms.
Topics: Alkaloids; Carbazoles; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Indole Alkaloids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
[Function of polynuclear neutrophils in patients with juvenile periodontitis and rapidly progressing periodontitis].
Topics: Aggressive Periodontitis; Cell Migration Inhibition; Chemotaxis, Leukocyte; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Periodontitis; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Dual effect of phorbol myristate acetate on chemoattractant-induced locomotion of human neutrophils.
Topics: Cells, Cultured; Chemotaxis, Leukocyte; Cytosol; Drug Synergism; Enzyme Activation; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1990 |
Utility of staurosporine in uncovering differences in the signal transduction pathways for superoxide production in neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Guinea Pigs; In Vitro Techniques; Isoquinolines; Models, Chemical; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Changes of fluorescence anisotropy in plasma membrane of human polymorphonuclear leukocytes during the respiratory burst phenomenon.
Topics: Adult; Cell Membrane; Diphenylhexatriene; Fluorescent Dyes; Humans; Kinetics; Luminescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Kinetic microplate assay for superoxide production by neutrophils and other phagocytic cells.
Topics: Cytochrome c Group; Humans; Kinetics; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Phagocytes; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Ferritin-dependent lipid peroxidation by stimulated neutrophils: inhibition by myeloperoxidase-derived hypochlorous acid but not by endogenous lactoferrin.
Topics: Ferritins; Humans; Hypochlorous Acid; Iron; Kinetics; Lactoferrin; Lipid Peroxidation; Liposomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Tetradecanoylphorbol Acetate | 1990 |
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Priming effect of fibronectin on respiratory burst of human neutrophils induced by formyl peptides and platelet-activating factor.
Topics: Dose-Response Relationship, Drug; Enzyme Activation; Fibronectins; Free Radicals; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Effects of dietary supplementation with eicosapentaenoic acid or gamma-linolenic acid on neutrophil phospholipid fatty acid composition and activation responses.
Topics: Animals; Chemotaxis, Leukocyte; Dietary Fats; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Leukotriene B4; Linoleic Acid; Linoleic Acids; Membrane Lipids; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Olive Oil; Oxygen; Phospholipids; Plant Oils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Effect of the spin trap 5,5 dimethyl-1-pyrroline-N-oxide (DMPO) on human neutrophil function: novel inhibition of neutrophil stimulus-response coupling?
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Concanavalin A; Cyclic N-Oxides; Cytochrome c Group; Cytoplasmic Granules; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Evidence for generation of a large amount of nitric oxide-like vascular smooth muscle relaxant by cholesterol-rich neutrophils.
Topics: Animals; Aorta; Arginine; Calcium; Cholesterol; Humans; In Vitro Techniques; Indomethacin; Kinetics; Liposomes; Muscle Relaxation; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Oxyhemoglobins; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of neutrophil superoxide secretion by the preservative, methylhydroxybenzoate: effects mediated by perturbation of intracellular Ca2+?
Topics: Calcium; Chelating Agents; Egtazic Acid; Free Radicals; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Parabens; Preservatives, Pharmaceutical; Superoxides; Tetradecanoylphorbol Acetate; Trypsin | 1990 |
Hydrogen peroxide release from human polymorphonuclear leukocytes measured with horseradish peroxidase and o-dianisidine. Effect of various stimulators and cytochalasin B.
Topics: Concanavalin A; Cytochalasin B; Dianisidine; Horseradish Peroxidase; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of polymorphonuclear leukocyte function by Legionella pneumophila exoproducts.
Topics: Calcimycin; Chemotaxis, Leukocyte; Ethyl Methanesulfonate; Legionella; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Potential roles of Mg2+ and Ca2+ in NADPH oxidase dependent superoxide anion synthesis by human neutrophils.
Topics: Calcimycin; Calcium; Cells, Cultured; Humans; Magnesium; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Differential regulation of 5-lipoxygenase and cyclo-oxygenase pathways of arachidonate metabolism in rat peritoneal leukocytes.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Female; In Vitro Techniques; Leukocytes; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
The effects of rhGM-CSF on the neutrophil respiratory burst when studied in whole blood.
Topics: Blood; Cells, Cultured; Colony-Stimulating Factors; Flow Cytometry; Fluoresceins; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1990 |
Neutrophil beta-2 microglobulin: an inflammatory mediator.
Topics: Adolescent; beta 2-Microglobulin; Cell Membrane; Cell Separation; Cytoplasmic Granules; Exocytosis; Humans; Immunoelectrophoresis, Two-Dimensional; Inflammation; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Hydrolases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1990 |
Recombinant C5a stimulates transcription rather than translation of interleukin-1 (IL-1) and tumor necrosis factor: translational signal provided by lipopolysaccharide or IL-1 itself.
Topics: Complement C5a; Gene Expression; Humans; Interleukin-1; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Protein Biosynthesis; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Correlation between chemotactic peptide-induced changes in chlorotetracycline fluorescence and F-actin content in human neutrophils: a role for membrane-associated calcium in the regulation of actin polymerization?
Topics: Actins; Calcium; Cell Membrane; Cell Movement; Chlortetracycline; Ethylmaleimide; Fluorescence; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymers; Protein Kinase C; Tetracaine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Stimulation of human polymorphonuclear leukocytes potentiates the uptake of diclofenac and the inhibition of chemotaxis.
Topics: Cells, Cultured; Chemotaxis, Leukocyte; Diclofenac; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1990 |
Effect of phorbol myristate acetate on processing of formyl peptide receptors by human neutrophils.
Topics: Binding, Competitive; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1990 |
[Adhesion receptors--regulators of respiratory burst in neutrophils].
Topics: Antibodies; Binding, Competitive; Disulfides; Fibronectins; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen; Plant Extracts; Receptors, Leukocyte-Adhesion; Sulfoxides; Tetradecanoylphorbol Acetate | 1990 |
Effect of nisoldipine on priming and activation of the human neutrophil respiratory burst.
Topics: Biotransformation; Calcium; Humans; Hydrogen Peroxide; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nisoldipine; Oxygen Consumption; Tetradecanoylphorbol Acetate | 1990 |
Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases.
Topics: Animals; Brain; Calpain; Chromatography, Gel; Cross Reactions; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Rats; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1990 |
A novel succinyl dipeptide stimulates directed cell migration by modulating protein kinase C activity.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line; Chemotactic Factors; Chemotaxis; Dipeptides; Endothelium, Vascular; Enzyme Activation; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphoproteins; Phosphorylation; Protein Kinase C; Succinates; Tetradecanoylphorbol Acetate | 1990 |
Difference in changes of membrane fluidity of polymorphonuclear leukocytes stimulated with phorbol myristate acetate and formyl-methionyl-leucyl-phenylalanine: role of excited oxygen species.
Topics: Adult; Cell Membrane; Granulomatous Disease, Chronic; Humans; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Toxic oxygen metabolite production by circulating phagocytic cells in inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Colitis, Ulcerative; Crohn Disease; Humans; Latex; Luminescent Measurements; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1990 |
Functional capacity of neutrophil granulocytes in deep-sea divers.
Topics: Adult; Diving; Humans; Hydrogen Peroxide; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Oxygen Consumption; Partial Pressure; Tetradecanoylphorbol Acetate | 1990 |
Identification of the proteolytically activated form of protein kinase C in stimulated human neutrophils.
Topics: Antibodies, Monoclonal; Humans; In Vitro Techniques; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
M5, a phosphoinositol-linked human myelomonocytic activation-associated antigen.
Topics: Antigens, Differentiation, Myelomonocytic; Cells, Cultured; Down-Regulation; Granulocytes; Humans; Lipopolysaccharides; Molecular Weight; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Precipitin Tests; Tetradecanoylphorbol Acetate; Up-Regulation | 1990 |
Lysophosphatidic acid, but not phosphatidic acid, is a potent Ca2(+)-mobilizing stimulus for fibroblasts. Evidence for an extracellular site of action.
Topics: Bradykinin; Calcium; Cells, Cultured; Cytoplasm; Extracellular Space; Fibroblasts; Humans; In Vitro Techniques; Inositol Phosphates; Lanthanum; Lysophospholipids; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidic Acids; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1990 |
Flow cytometric study of the activation of polymorphonuclear cells.
Topics: Actins; Antibodies, Monoclonal; Antigens, Surface; Chemotaxis, Leukocyte; Evaluation Studies as Topic; Flow Cytometry; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phalloidine; Rhodamines; Tetradecanoylphorbol Acetate | 1990 |
Reduced oxidative activity of circulating neutrophils in patients after myocardial infarction.
Topics: Aged; Humans; Middle Aged; Myocardial Infarction; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Inhibitory effects of antithyroid drugs on oxygen radical formation in human neutrophils.
Topics: Antithyroid Agents; Calcimycin; Cell Count; Chemotaxis; Concanavalin A; Humans; Hydrogen Peroxide; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Propylthiouracil; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Neutrophil function in psoriasis: effects of retinoids.
Topics: Acitretin; Dermatologic Agents; Etretinate; Female; Humans; In Vitro Techniques; Isotretinoin; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Psoriasis; Retinoids; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Induction of human basophil histamine release by a novel protein kinase C activator, sn-1,2-isopropylidene-3-decanoyl-glycerol (IpOCOC9): partial characterization of secretagogue characteristics.
Topics: Acetophenones; Antigens, Differentiation, B-Lymphocyte; Basophils; Calcium; Cyclopentanes; Decanoic Acids; Deoxyglucose; Dioxoles; Enzyme Activation; Ethylmaleimide; Histamine Release; Hot Temperature; Humans; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptors, Fc; Receptors, IgE; Secretory Rate; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Triglycerides | 1988 |
Impermeant stilbene disulfonic acids block chemotactic peptide receptor function on human granulocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Calcimycin; Cell Aggregation; Granulocytes; Humans; In Vitro Techniques; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Stilbenes; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Modulation of human leukocyte histamine release by sn-1,2-isopropylidene-3-decanoyl-glycerol and decanoic acid cyclopentyl methylester in comparison with effects of synthetic diacylglycerols and a phorbol ester.
Topics: Calcimycin; Cyclopentanes; Decanoic Acids; Diglycerides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Triglycerides | 1989 |
Functional differences of human basophils with different densities.
Topics: Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Centrifugation, Density Gradient; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; Leukocyte Count; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1989 |
Differential release of mediators from human basophils: differences in arachidonic acid metabolism following activation by unrelated stimuli.
Topics: Arachidonic Acids; Basophils; Calcium; Complement C5; Complement C5a; Deuterium; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Signal Transduction; SRS-A; Tetradecanoylphorbol Acetate | 1989 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Tyrosine phosphorylation in human neutrophil.
Topics: Cinnamates; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; In Vitro Techniques; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Sulfides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1989 |
Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils.
Topics: Calcimycin; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glycerides; Glycerophosphates; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidic Acids; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Arachidonic acid release in rabbit neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1989 |
Dynamics of the diradylglycerol responses of stimulated phagocytes.
Topics: Calcimycin; Calcium; Cytochalasin B; Diglycerides; Gas Chromatography-Mass Spectrometry; Glycerides; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phagocytes; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Increased phagocytic cell chemiluminescence in patients with cystic fibrosis.
Topics: Adolescent; Adult; Calcimycin; Child; Cystic Fibrosis; Humans; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1).
Topics: Animals; Calcimycin; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Exocytotic enzyme release from rabbit polymorphonuclear leukocytes after treatment with fluoride and calcium.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Calcium Radioisotopes; Exocytosis; Glyceric Acids; Glycogen; Glycolysis; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1989 |
Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Cell Separation; Female; Humans; Inflammatory Bowel Diseases; Interferon-gamma; Intestinal Mucosa; Macrophage Activation; Macrophages; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin.
Topics: Benzofurans; Calcimycin; Calcium; Computer Simulation; Erythrocytes; Fluorescent Dyes; Fura-2; Homeostasis; Humans; Manganese; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1989 |
Acetyltransferase activity and production of platelet-activating factor by human neutrophils activated with various stimuli.
Topics: Acetyltransferases; Calcimycin; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Formation of lipoxins by rat basophilic leukemia cells.
Topics: Animals; Calcimycin; Cell Line; Hydroxyeicosatetraenoic Acids; Leukemia, Basophilic, Acute; Leukotrienes; Lipid Peroxides; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Rats; Tetradecanoylphorbol Acetate | 1989 |
Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutr
Topics: Cell Line; Diglycerides; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine | 1989 |
Membrane oxidative metabolism of human eosinophilic cell line EoL-1 in response to phorbol diester and formyl peptide: synergistic augmentation by interferon-gamma and tumor necrosis factor.
Topics: Azides; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Drug Synergism; Eosinophils; Humans; Interferon-gamma; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Tumor Necrosis Factor; Sodium Azide; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1989 |
Diacylglycerol generation and phosphoinositide turnover in human neutrophils: effects of particulate versus soluble stimuli.
Topics: Diglycerides; Glycerides; Humans; Hydrolysis; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Phosphatidylinositols; Phospholipids; Solubility; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Natural inhibitor from Candida albicans blocks release of azurophil and specific granule contents by chemotactic peptide-stimulated human neutrophils.
Topics: Actin Cytoskeleton; Actins; Candida albicans; Cell Survival; Exocytosis; Immunity, Cellular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Tumor necrosis factor as an activator of human granulocytes. Potentiation of the metabolisms triggered by the Ca2+-mobilizing agonists.
Topics: Adjuvants, Immunologic; Adult; Calcium Channel Agonists; Concanavalin A; Cyclic AMP; Ethers; Granulocytes; Humans; Ionomycin; Ionophores; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Wheat Germ Agglutinins | 1989 |
Phosphorylation of both 47 and 49kDa proteins accompanies superoxide release by neutrophils.
Topics: Animals; Diglycerides; Enzyme Activation; Guinea Pigs; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphoproteins; Phosphorylation; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Fluoride activation of neutrophils: similarities to formylmethionyl-leucyl-phenylalanine.
Topics: Calcium; Cholera Toxin; Cytochalasin B; Fluorides; Humans; In Vitro Techniques; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.
Topics: Calcimycin; Calcium; Cytosol; Humans; Kinetics; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxidation-Reduction; Salmonella; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Role of myeloperoxidase in intracellular and extracellular chemiluminescence of neutrophils.
Topics: Azides; Humans; Hydrogen Peroxide; Immunoglobulin G; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Peroxidase; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Erythromycin and roxithromycin potentiate human neutrophil locomotion in vitro by inhibition of leukoattractant-activated superoxide generation and autooxidation.
Topics: Calcimycin; Cell Movement; Erythromycin; Humans; In Vitro Techniques; Leucomycins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Propionates; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Characterization of the luminol-amplified light-generating reaction induced in human monocytes.
Topics: Azides; Catalase; Ethers; Horseradish Peroxidase; Humans; Hydrogen Peroxide; In Vitro Techniques; Ionomycin; Leukocytes, Mononuclear; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Responses of neutrophilic granulocytes in vitro of asthmatic and healthy subjects and the degree of inhibition by several drugs.
Topics: Adolescent; Albuterol; Asthma; Calcimycin; Child; Child, Preschool; Cromolyn Sodium; Enzyme Inhibitors; Granulocytes; Humans; Imidazoles; In Vitro Techniques; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Enhancement of superoxide anion release by granulocytes harvested from patients receiving granulocyte-macrophage colony-stimulating factor.
Topics: Adult; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Growth Substances; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Sarcoma; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Dopamine inhibition of superoxide anion production by polymorphonuclear leukocytes.
Topics: Chemotaxis, Leukocyte; Cyclic AMP; Dopamine; Humans; In Vitro Techniques; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.
Topics: Antibodies, Monoclonal; Calpain; Cell Membrane; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Modulation of polymorphonuclear leukocyte microbicidal activity and oxidative metabolism by fibrinogen degradation products D and E.
Topics: Adult; Arachidonic Acids; Blood Bactericidal Activity; Blood Coagulation Factors; Chemotaxis, Leukocyte; Enzyme Activation; Fibrin Fibrinogen Degradation Products; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytosis; Protein Binding; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
The calcium ionophore ionomycin can prime, but not activate, the reactive oxygen generating system in differentiated HL-60 cells.
Topics: Adult; Calcium; Ethers; Humans; Hydrogen Peroxide; Ionomycin; Ionophores; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Correlation between neutrophil superoxide formation, luminol-augmented chemiluminescence and intracellular Ca2+ levels upon stimulation with leukotriene B4, formylpeptide and phorbolester.
Topics: Calcium; Humans; Leukotriene B4; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyridazines; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Effect of granulocyte-macrophage colony-stimulating factor on superoxide production in cytoplasts and intact human neutrophils: role of protein kinase and G-proteins.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Botulinum Toxins; Colony-Stimulating Factors; Cytoplasm; Cytoskeletal Proteins; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; GTP-Binding Proteins; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Effects of extracellular pH on neutrophil superoxide anion production, and chemiluminescence augmented with luminol, lucigenin or DMNH.
Topics: Acridines; Humans; Hydrazines; Hydrogen-Ion Concentration; In Vitro Techniques; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Inhibitory effect of antibiotic cerulenin on the respiratory burst in phagocytes. II. Inhibition by cerulenin of intracellular calcium mobilization in human neutrophils.
Topics: Antifungal Agents; Bacterial Toxins; Calcimycin; Calcium; Cerulenin; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phagocytes; Phagocytosis; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Lysophosphatides enhance superoxide responses of stimulated human neutrophils.
Topics: Adjuvants, Immunologic; Antigen-Antibody Complex; Hemolysis; Histidine; Humans; In Vitro Techniques; Lipopolysaccharides; Lysophospholipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phytohemagglutinins; Superoxides; Teichoic Acids; Tetradecanoylphorbol Acetate | 1989 |
Prolonged exposure of neutrophils to saline or bronchoalveolar lavage fluid does not alter superoxide anion generation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Culture Media; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sheep; Sodium Chloride; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Involvement of guanine nucleotides in superoxide release by fluoride-treated neutrophils. Implications for a role of a guanine nucleotide regulatory protein.
Topics: Adenine Nucleotides; Digitonin; GTP-Binding Proteins; Guanine Nucleotides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Ribavirin; Signal Transduction; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Protease-modulation of neutrophil superoxide response.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Cathepsin G; Cathepsins; Chymotrypsin; Drug Combinations; Humans; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peptide Hydrolases; Serine Endopeptidases; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
An assessment of the effects of glucocorticoids on degranulation, chemotaxis, binding to vascular endothelium and formation of leukotriene B4 by purified human neutrophils.
Topics: Cell Adhesion; Chemotaxis, Leukocyte; Cytoplasmic Granules; Dexamethasone; Endothelium, Vascular; Glucocorticoids; Humans; In Vitro Techniques; Leukotriene B4; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Complement; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of superoxide anion radical production by ebselen (PZ51) and its sulfur analogue (PZ25) in guinea pig alveolar macrophages.
Topics: Animals; Antioxidants; Azoles; Free Radicals; Guinea Pigs; In Vitro Techniques; Isoindoles; Macrophages; Male; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Organoselenium Compounds; Pulmonary Alveoli; Selenium; Superoxides; Tetradecanoylphorbol Acetate; Thiazoles | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Occult intracellular calcium pools: relevance to neutrophil oxidant production.
Topics: Calcimycin; Calcium; Cytosol; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Verapamil | 1989 |
Actions of the protease inhibitor phenylmethylsulfonyl fluoride on neutrophil granule enzyme secretion and superoxide production induced by fMet-Leu-Phe and phorbol 12-myristate-13-acetate.
Topics: Actins; Animals; Calcium; Cytoplasmic Granules; Hydrogen-Ion Concentration; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylmethylsulfonyl Fluoride; Phosphoproteins; Phosphorylation; Protease Inhibitors; Rabbits; Sulfones; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Priming of human neutrophils with N-formyl-methionyl-leucyl-phenylalanine by a calcium-independent, pertussis toxin-insensitive pathway.
Topics: Calcium; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Receptors, Formyl Peptide; Receptors, Immunologic; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Human neutrophil gelatinase is a component of specific granules.
Topics: Blotting, Western; Cytoplasmic Granules; Gelatinases; Humans; Immunohistochemistry; Immunosorbent Techniques; Lactoferrin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microscopy, Electron; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepsin A; Peroxidase; Tetradecanoylphorbol Acetate | 1989 |
Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability.
Topics: Adult; Bronchoalveolar Lavage Fluid; Cell Membrane Permeability; Cell Movement; Female; Humans; Leukotriene B4; Lung; Male; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proteins; Pulmonary Alveoli; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Desensitization of calcium mobilization and cell function in human neutrophils.
Topics: Calcium; Cell Aggregation; Dose-Response Relationship, Drug; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Cyclic AMP inhibits chemotactic-peptide-induced but not Ca2+-ionophore- or tetradecanoylphorbol-acetate-induced enzyme secretion in guinea pig neutrophils.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bucladesine; Calcimycin; Cyclic AMP; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein.
Topics: Alkaloids; Animals; Diglycerides; Diterpenes; Glycerides; Guinea Pigs; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Comparative effects of F1 and P1 fractions obtained from a Klebsiella pneumoniae glycoproteic extract (RU 41740) on polymorphonuclear leukocytes.
Topics: Adjuvants, Immunologic; Bacterial Proteins; Calcimycin; Chemical Fractionation; Glucuronidase; Humans; Klebsiella pneumoniae; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Superoxide generation is inhibited by phospholipase A2 inhibitors. Role for phospholipase A2 in the activation of the NADPH oxidase.
Topics: Acetophenones; Amino Alcohols; Arachidonic Acid; Arachidonic Acids; Cell-Free System; Enzyme Activation; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Quinacrine; Sodium Dodecyl Sulfate; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Staurosporine inhibits the respiratory burst and induces exocytosis in human neutrophils.
Topics: Alkaloids; Aminoquinolines; Calcium; Complement C5a; Cytosol; Exocytosis; Fluorescent Dyes; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
A Chinese traditional medicine, juzentaihoto, inhibits the O2- generation by macrophages.
Topics: Animals; Cinnamates; Drugs, Chinese Herbal; Guinea Pigs; In Vitro Techniques; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Plant Extracts; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
The effect of azelastine on neutrophil and eosinophil generation of superoxide.
Topics: Adult; Calcimycin; Eosinophils; Free Radicals; Histamine H1 Antagonists; Humans; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Protein Kinase C; Pyridazines; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antigens, Differentiation; CD11 Antigens; CD18 Antigens; Chemical Phenomena; Chemistry; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Molecular Sequence Data; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate | 1989 |
Stimulation and inhibition of secretion by phorbol myristate acetate in different cell types.
Topics: Animals; Blood Platelets; Calcimycin; Cell Line; Drug Interactions; Granulocytes; Histamine Release; Humans; Lysosomes; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Phorbols; Rats; Serotonin; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Activation of protein kinase C in human neutrophils attenuates agonist-stimulated rises in cytosolic free Ca2+ concentration by inhibiting bivalent-cation influx and intracellular Ca2+ release in addition to stimulating Ca2+ efflux.
Topics: Benzofurans; Biological Transport; Calcium; Cytosol; Enzyme Activation; Fluorescent Dyes; Fura-2; Humans; In Vitro Techniques; Ionomycin; Kinetics; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1989 |
Enhancement of normal neutrophil chemiluminescence by chronic granulomatous disease neutrophils.
Topics: Acridines; Adolescent; Child; Female; Granulomatous Disease, Chronic; Humans; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1989 |
A novel neutrophil adherence test effectively reflects the activated state of neutrophils.
Topics: Cell Adhesion; Humans; Kinetics; Lymphocyte Activation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1989 |
Altered neutrophils in mice immune to experimental Naegleria amoebic meningoencephalitis.
Topics: Amebiasis; Animals; Antigens, Protozoan; Disease Models, Animal; Female; Immunity; Luminescent Measurements; Meningoencephalitis; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Naegleria; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1989 |
CDw17: a neutrophil glycolipid antigen regulated by activation.
Topics: Antigens, CD; Cell Membrane; Cytoplasmic Granules; Dose-Response Relationship, Drug; Exocytosis; Glycosphingolipids; Humans; Lactosylceramides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Leukotriene formation by human polymorphonuclear leukocytes from endogenous arachidonate. Physiological triggers and modulation by prostanoids.
Topics: Arachidonic Acids; Chromatography, High Pressure Liquid; Complement System Proteins; Humans; In Vitro Techniques; Kinetics; Leukotrienes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thimerosal | 1989 |
Human neutrophil chemiluminescence and f-Meth-Leu-Phe receptor exposure in bacterial infections.
Topics: Bacterial Infections; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1989 |
Differential activation by fMet-Leu-Phe and phorbol ester of a plasma membrane phosphatidylcholine-specific phospholipase D in human neutrophil.
Topics: Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Hydrolysis; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Human neutrophils contain distinct cytosolic and particulate tyrosine kinase activities: possible role in neutrophil activation.
Topics: Cations, Divalent; Chromatography, Gel; Chromatography, Ion Exchange; Cinnamates; Cytosol; Humans; Isoenzymes; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein-Tyrosine Kinases; Sulfides; Tetradecanoylphorbol Acetate | 1989 |
Respiratory burst oscillations in human neutrophils and their correlation with fluctuations in apparent cell shape.
Topics: Androstadienes; Benzofurans; Calcium; Cytosol; Fura-2; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Temperature; Tetradecanoylphorbol Acetate | 1989 |
Phorbol esters and chemotactic factor induce distinct changes in cytoplasmic Ca2+ and pH in granulocytic like HL60 cells.
Topics: Amiloride; Calcium; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Granulocytes; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Polymorphonuclear leukocyte chemiluminescence induced by formylmethionyl-leucyl-phenylalanine and phorbol myristate acetate: effects of catalase and superoxide dismutase.
Topics: Adult; Catalase; Cell-Free System; Cytochrome c Group; Humans; Hydrogen Peroxide; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peroxidase; Scopoletin; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1987 |
Modulation of human neutrophil LTA hydrolase activity by phorbol myristate acetate.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Interactions; Epoxide Hydrolases; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Tetradecanoylphorbol Acetate | 1987 |
Separation and function of neutrophil karyogranuloplasts and comparison with cytoplasts and intact cells.
Topics: Cell Aggregation; Cell Movement; Cell Nucleus; Cell Separation; Cytoplasmic Granules; Humans; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organoids; Osmolar Concentration; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Purification and properties of porcine polymorphonuclear cells.
Topics: Animals; Calcimycin; Cell Separation; Centrifugation, Density Gradient; Chemotaxis, Leukocyte; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Povidone; Silicon Dioxide; Swine; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Independent regulation of human neutrophil chemotactic receptors after activation.
Topics: Caseins; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Cytochalasin B; Flow Cytometry; Fluorescent Dyes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Enhancement of neutrophil superoxide production by preincubation with recombinant human tumor necrosis factor.
Topics: Actins; Cell Aggregation; Drug Synergism; Exocytosis; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils.
Topics: Calcimycin; Glucuronidase; Humans; In Vitro Techniques; Kinetics; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1987 |
Effect of an inhibitor of protein kinase C on human polymorphonuclear leukocyte degranulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C mediates human neutrophil cytotoxicity.
Topics: Cytotoxicity, Immunologic; Diacylglycerol Kinase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases; Protein Kinase C; Pyrimidinones; Tetradecanoylphorbol Acetate; Thiazoles | 1987 |
Dissociation of the 47-kilodalton protein phosphorylation from degranulation and superoxide production in neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylglucosaminidase; Animals; Cytochalasin B; Cytoplasmic Granules; Drug Interactions; Hexosaminidases; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Different calcium and oxidative metabolic responses in human blood monocytes during exposure to various agonists.
Topics: Calcium; Cell Membrane Permeability; Concanavalin A; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Platelet enhancement of O2-. responses in stimulated human neutrophils. Identification of platelet factor as adenine nucleotide.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Adult; Alkaline Phosphatase; Antigen-Antibody Complex; Blood Platelets; Cell Fractionation; Cell-Free System; Hot Temperature; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Intracellular Ca2+ mobilization in immature and more mature U937 induced to differentiate by dimethyl sulfoxide or phorbol myristate acetate.
Topics: Calcium; Cell Differentiation; Cell Line; Cytoplasm; Dimethyl Sulfoxide; Humans; Leukotriene B4; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1988 |
Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C.
Topics: Animals; Antibodies, Monoclonal; Calpain; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Hydrolases; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Characterization of the neutrophil respiratory burst in atopy.
Topics: Calcimycin; Histamine; Humans; Hypersensitivity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
The influence of chlorhexidine on superoxide generation by induced human neutrophils.
Topics: Chlorhexidine; Detergents; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Activation of human neutrophil gelatinase by endogenous serine proteinases.
Topics: Basement Membrane; Collagen; Cytochalasin B; Enzyme Activation; Gelatin; Gelatinases; Humans; In Vitro Techniques; Kidney Glomerulus; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepsin A; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1988 |
Fluoride can activate the respiratory burst independently of Ca2+, stimulation of phosphoinositide turnover and protein kinase C translocation in primed human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Calcium; GTP-Binding Proteins; Humans; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Pertussis Toxin; Phosphatidylinositols; Piperazines; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Inactivation of alpha-1-proteinase inhibitor in serum by stimulated human polymorphonuclear leucocytes. Evidence for a myeloperoxidase-dependent mechanism.
Topics: alpha 1-Antitrypsin; Antioxidants; Blood Proteins; Cell-Free System; Cytochalasin B; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Peroxidase; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1988 |
Hydroxy radical as autotoxin in chemotactically activated neutrophils.
Topics: Animals; Catalase; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Deferoxamine; Dimethyl Sulfoxide; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxidation-Reduction; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1987 |
Regulatory effects of adenosine and adenine nucleotides on oxygen radical responses of neutrophils.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Antigen-Antibody Complex; Cytochalasin B; Dose-Response Relationship, Drug; Free Radicals; Humans; Hydrogen Peroxide; Hydrolases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Rats; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1988 |
The priming of neutrophils by lipopolysaccharide for production of intracellular platelet-activating factor. Potential role in mediation of enhanced superoxide secretion.
Topics: Adjuvants, Immunologic; Body Fluids; Calcium; Cytosol; Dose-Response Relationship, Immunologic; Humans; Intracellular Fluid; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Studies with protein kinase C inhibitors presently available cannot elucidate the role of protein kinase C in the activation of NADPH oxidase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cytochalasin B; Enzyme Activation; Female; Humans; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Phorbol myristate acetate potentiates superoxide release and membrane depolarization without affecting an increase in cytoplasmic free calcium in human granulocytes stimulated by the chemotactic peptide, lectins and the calcium ionophore.
Topics: Calcium; Cytoplasm; Dose-Response Relationship, Drug; Ethers; Granulocytes; Humans; In Vitro Techniques; Ionomycin; Lectins; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Disseminated pustular dermatosis in polycythemia vera. Relationship with neutrophilic dermatosis of myeloproliferative disorders: study of neutrophil function.
Topics: Aged; Dapsone; Humans; In Vitro Techniques; Male; Mouth Mucosa; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polycythemia Vera; Skin; Skin Diseases, Vesiculobullous; Stomatitis; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Stimulus-dependent differences in superoxide anion generation by normal human eosinophils and neutrophils.
Topics: Adolescent; Adult; Calcimycin; Cell Separation; Centrifugation, Density Gradient; Cytochalasin B; Eosinophils; Humans; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Platelet activating factor and leukotriene B4 induce hyperpolarization of human endothelial cells but depolarization of neutrophils.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Modulation of leukotriene release from human polymorphonuclear leucocytes by PMA and arachidonic acid.
Topics: Arachidonic Acids; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; SRS-A; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Activation of monocytes by interferon-gamma has no effect on the level or affinity of the nicotinamide adenine dinucleotide-phosphate oxidase and on agonist-dependent superoxide formation.
Topics: Calcium; Cells, Cultured; Cytochrome b Group; Humans; Hydrogen Peroxide; Interferon-gamma; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Oxygen Consumption; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Membrane-associated protein kinase C activity in superoxide-producing human polymorphonuclear leukocytes.
Topics: Calcimycin; Cell Membrane; Cells, Cultured; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Separation; Concanavalin A; Cytoplasm; Digitonin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Protons; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Propionic acid-induced calcium mobilization in human neutrophils.
Topics: Calcium; Cell Line; Cholera Toxin; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid, Acute; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Propionates; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Effects of ethanol on mechanisms for secretory and aggregatory responses of human granulocytes.
Topics: Calcium; Cell Aggregation; Ethanol; Humans; In Vitro Techniques; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Activation of the neutrophil by calcium-mobilizing ligands. I. A chemotactic peptide and the lectin concanavalin A stimulate superoxide anion generation but elicit different calcium movements and phosphoinositide remodeling.
Topics: Benzofurans; Calcium; Concanavalin A; Fura-2; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Permeability; Phosphatidylinositols; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils.
Topics: alpha 1-Antitrypsin; Chemical Fractionation; Culture Media; Enzyme Activation; Gelatinases; Humans; Metalloendopeptidases; Microbial Collagenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepsin A; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of neutrophil functions by platelets and platelet-derived products: description of multiple inhibitory properties.
Topics: Anti-Inflammatory Agents; Blood Platelets; Cell Fractionation; Cell-Free System; Chemotaxis, Leukocyte; Cytoplasmic Granules; Humans; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Metabolism of leukotriene B4 by activated human polymorphonuclear granulocytes.
Topics: Calcimycin; Cell-Free System; Diazonium Compounds; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Immunologic; Receptors, Leukotriene B4; Sulfanilic Acids; Tetradecanoylphorbol Acetate; Thermolysin | 1988 |
Myotonic dystrophy: defective oxidative burst of polymorphonuclear leukocytes.
Topics: Adult; Humans; Membrane Potentials; Middle Aged; Myotonic Dystrophy; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
The effect of the NADPH oxidase inhibitor diphenyleneiodonium on aerobic and anaerobic microbicidal activities of human neutrophils.
Topics: Aerobiosis; Anaerobiosis; Blood Bactericidal Activity; Cell Movement; Cell Survival; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Onium Compounds; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst.
Topics: Diglycerides; Glycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphatidylinositols; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
A study on the role of protein kinase C and intracellular calcium in the activation of superoxide generation.
Topics: Calcimycin; Calcium; Cell Membrane; Diglycerides; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Effects of recombinant human granulocyte-macrophage colony-stimulating factor on intracellular pH in mature granulocytes.
Topics: Amiloride; Antibodies, Monoclonal; Carrier Proteins; Colony-Stimulating Factors; Cytosol; Glycolysis; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Growth Substances; Hydrogen-Ion Concentration; Mitochondria; N-Formylmethionine Leucyl-Phenylalanine; Ouabain; Receptors, Formyl Peptide; Receptors, Immunologic; Recombinant Proteins; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1988 |
A time-course study on superoxide generation and protein kinase C activation in human neutrophils.
Topics: Calcimycin; Cell Membrane; Ethers; Humans; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Two transduction sequences are necessary for neutrophil activation by receptor agonists.
Topics: Androstadienes; Complement C5; Complement C5a; Exocytosis; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Biochemical mechanisms involved in the priming of neutrophils by tumor necrosis factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Piperazines; Protein Kinase C; Sodium; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1988 |
Superoxide anion production in glass-adherent polymorphonuclear leukocytes and its relationship to calcium movement.
Topics: Calcium; Cell Adhesion; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of neutrophil superoxide anion generation by platelet products: role of adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Deaminase; Blood Platelets; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Superoxide production by neutrophils in a model of adult respiratory distress syndrome.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Endotoxins; Escherichia coli; Kinetics; Leukocyte Count; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Respiratory Distress Syndrome; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1988 |
Activation of inositol phospholipid breakdown in HL60 cells by P2-purinergic receptors for extracellular ATP. Evidence for mediation by both pertussis toxin-sensitive and pertussis toxin-insensitive mechanisms.
Topics: Adenosine Triphosphate; Calcium; Cell Line; Cytosol; Humans; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Phosphatidylinositols; Receptors, Purinergic; Sodium Chloride; Sodium Fluoride; Sugar Phosphates; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Effect of defibrotide on polymorphonuclear leukocytes: modulation of calcium entry and availability.
Topics: Biological Availability; Calcimycin; Calcium; Fibrinolytic Agents; Free Radicals; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polydeoxyribonucleotides; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Dieldrin activates rat neutrophils in vitro.
Topics: Animals; Calcimycin; Calcium; Dieldrin; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Studies on opsonized zymozan, FMLP, carbachol, PMA and A23187 stimulated respiratory burst of human PMNLs.
Topics: Adult; Aging; Calcimycin; Carbachol; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Halothane, an inhalation anesthetic, activates protein kinase C and superoxide generation by neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Cytoplasm; Enzyme Activation; Guinea Pigs; Halothane; Histones; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphatidylserines; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction.
Topics: Exocytosis; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepstatins; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Effect of the 5-lipoxygenase inhibitor piriprost on superoxide production by human neutrophils.
Topics: Arachidonate Lipoxygenases; Epoprostenol; Humans; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
The degranulation response in differentiated HL-60 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Immunoglobulin G; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate | 1988 |
Inactivation of enzymes and oxidative modification of proteins by stimulated neutrophils.
Topics: Blood Bactericidal Activity; Cell Line; Chelating Agents; Chemical Phenomena; Chemistry; Ferric Compounds; Glutamate-Ammonia Ligase; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Rhein: an anthraquinone that modulates superoxide anion production from human neutrophils.
Topics: Adult; Anthraquinones; Calcimycin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Analysis of calcium homeostasis in activated human polymorphonuclear leukocytes. Evidence for two distinct mechanisms for lowering cytosolic calcium.
Topics: Alkaloids; Benzofurans; Calcium; Cytosol; Diglycerides; Ethers; Fura-2; Homeostasis; Humans; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Lack of effect of pertussis toxin on TNF-alpha-induced formation of reactive oxygen intermediates by human neutrophils.
Topics: Calcium; Cell Adhesion; Fetal Blood; Free Radicals; Humans; Hydrogen Peroxide; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Pertussis Toxin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1989 |
Aggregation of complement receptors on human neutrophils in the absence of ligand.
Topics: Antigens, Surface; Cell Membrane; Humans; Ligands; Macromolecular Substances; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate | 1987 |
Intensity and kinetics of the respiratory burst of human neutrophils in relation to receptor occupancy and rate of occupation by formylmethionylleucylphenylalanine.
Topics: Adult; Concanavalin A; Drug Tolerance; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Stimulus-dependent inhibition of superoxide generation by prostaglandins.
Topics: Alprostadil; Cyclic AMP; Depression, Chemical; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Prostaglandins; Prostaglandins E; Protein Binding; Superoxides; Tetradecanoylphorbol Acetate; Tritium; Zymosan | 1985 |
Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils.
Topics: Animals; Diglycerides; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate | 1985 |
Prostaglandins E1 and E2 enhance the stimulation of superoxide release by 1-oleoyl-2-acetylglycerol from human neutrophils.
Topics: Alprostadil; Calcimycin; Diglycerides; Dinoprostone; Enzyme Activation; Glycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Protein Kinase C; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.
Topics: Acetylglucosaminidase; Animals; Calcimycin; Calcium; Cytoplasmic Granules; Leukotriene B4; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Rabbits; Sodium; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1985 |
Cytochrome b translocation to human neutrophil plasma membranes and superoxide release. Differential effects of N-formylmethionylleucylphenylalanine, phorbol myristate acetate, and A23187.
Topics: Calcimycin; Cell Fractionation; Cell Membrane; Child; Cytochrome b Group; Cytoplasmic Granules; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Pertussis but not cholera toxin inhibits the stimulated increase in actin association with the cytoskeleton in rabbit neutrophils: role of the "G proteins" in stimulus-response coupling.
Topics: Actins; Animals; Bacterial Toxins; Calcimycin; Calcium; Cholera Toxin; Cytoskeleton; GTP-Binding Proteins; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Binding; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
Stimulus interactions in release of superoxide anion (O2-) from human neutrophils. Further evidence for multiple pathways of activation.
Topics: Adult; Arachidonic Acid; Arachidonic Acids; Complement C5; Complement C5a; Concanavalin A; Drug Synergism; Egtazic Acid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Surface contact inhibits neutrophil superoxide generation induced by soluble stimuli.
Topics: Cell Adhesion; Cyclic AMP; Cytochalasin B; Humans; Hydrogen Peroxide; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Surface Properties; Tetradecanoylphorbol Acetate | 1985 |
Inhibition by verapamil of neutrophil responses to formylmethionylleucylphenylalanine and phorbol myristate acetate. Mechanisms involving Ca2+ changes, cyclic AMP and protein kinase C.
Topics: Calcium; Cell Membrane; Cyclic AMP; Cytoplasmic Granules; Cytosol; Enzyme Activation; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phorbols; Phosphatidylserines; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Verapamil | 1985 |
Regulation of the oxidative response of human granulocytes to chemoattractants. No evidence for stimulated traffic of redox enzymes between endo and plasma membranes.
Topics: Cell Fractionation; Centrifugation, Density Gradient; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Cytochrome b Group; Flavins; Granulocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Oxygen; Photosystem II Protein Complex; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Role of enhanced inositol phospholipid metabolism in neutrophil activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Proteins; Calcimycin; Calcium; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Effects of chemotactic factors and other agents on the amounts of actin and a 65,000-mol-wt protein associated with the cytoskeleton of rabbit and human neutrophils.
Topics: Actins; Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cytoskeleton; Glucose; Humans; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate; Urea; Water-Electrolyte Balance | 1985 |
Unique inhibitory profile of platelet activating factor induced calcium mobilization, polyphosphoinositide turnover and granule enzyme secretion in rabbit neutrophils towards pertussis toxin and phorbol ester.
Topics: Aminoquinolines; Animals; Bacterial Toxins; Calcium; Cytoplasmic Granules; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbols; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Diverse involvements of Ni protein in superoxide anion production in polymorphonuclear leukocytes depending on the type of membrane stimulants.
Topics: Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Calcimycin; Calcium; Concanavalin A; Female; GTP-Binding Proteins; Guinea Pigs; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
Superoxide generation by human blood leucocytes under the effect of cytolytic agents.
Topics: Cytochalasins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phytohemagglutinins; Polyanetholesulfonate; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Response of superoxide anion production by guinea pig eosinophils to various soluble stimuli: comparison to neutrophils.
Topics: Animals; Cytochalasin B; Digitonin; Eosinophils; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Modulation of neutrophil-reduced pyridine nucleotide content following stimulation with phorbol myristate acetate and chemotactic factors.
Topics: Complement C5; Complement C5a; Cytochalasin B; Dose-Response Relationship, Drug; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Effect of benzydamine on exocytosis and respiratory burst in human neutrophils and mononuclear phagocytes.
Topics: Benzydamine; Calcimycin; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Glucuronidase; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytes; Pyrazoles; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Effect of allopurinol on neutrophil superoxide production, chemotaxis, or degranulation.
Topics: Allopurinol; Animals; Carrageenan; Drug Interactions; Edema; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1985 |
Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.
Topics: Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; Inositol Phosphates; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Modulation of human neutrophil effector functions by monoclonal antibodies against surface membrane molecules of 94,000 and 180,000 molecular weight.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Cell Adhesion; Chemotaxis, Leukocyte; Female; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Mice; Mice, Inbred BALB C; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Neutrophils may directly synthesize both H2O2 and O2- since surface stimuli induce their release in stimulus-specific ratios.
Topics: Antigen-Antibody Complex; Catalase; Enzyme-Linked Immunosorbent Assay; Histocytochemistry; Humans; Hydrogen Peroxide; Immunoglobulin G; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Inhibition of neutrophil oxidative metabolism by lysosomotropic weak bases.
Topics: Ammonium Chloride; Chloroquine; Clindamycin; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Methylamines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Role of protein kinases in stimulation of human polymorphonuclear leukocyte oxidative metabolism by various agonists. Differential effects of a novel protein kinase inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Complement C5; Complement C5a; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Oxygen Consumption; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Chemoattractant-mediated stimulation of the respiratory burst in human polymorphonuclear leukocytes may require appearance of protein kinase activity in the cells' particulate fraction.
Topics: Alcohols; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Modulation of neutrophil oxidative responses to soluble stimuli by platelet-activating factor.
Topics: Adult; Diglycerides; Fatty Acids; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Oxygen Consumption; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Treatment of rabbit neutrophils with phorbol esters results in increased ADP-ribosylation catalyzed by pertussis toxin and inhibition of the GTPase stimulated by fMet-Leu-Phe.
Topics: Adenosine Diphosphate Ribose; Animals; GTP Phosphohydrolases; GTP-Binding Proteins; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleoside Diphosphate Sugars; Pertussis Toxin; Phorbols; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Phorbol 12, myristate 13, acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophils.
Topics: Calcium; Drug Synergism; Enzyme Activation; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbols; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1986 |
Complete dissociation between the activation of phosphoinositide turnover and of NADPH oxidase by formyl-methionyl-leucyl-phenylalanine in human neutrophils depleted of Ca2+ and primed by subthreshold doses of phorbol 12,myristate 13,acetate.
Topics: Calcium; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inositol Phosphates; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbols; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1986 |
A combination of a T cell-derived lymphokine differentiation-inducing activity and a physiologic concentration of retinoic acid induces HL-60 to differentiate to cells with functional chemotactic peptide receptors.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Chemotaxis; Cytochalasin B; Dimethylformamide; Humans; Kinetics; Leukemia, Lymphoid; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Receptors, Formyl Peptide; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.
Topics: Cathepsin G; Cathepsins; Cell Differentiation; Cell Line; Chemotaxis; Cholecalciferol; Cyclic AMP; DNA; Humans; Leukemia, Myeloid, Acute; Macrophages; Microbial Collagenase; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phorbols; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of chemotactic peptide-induced phosphoinositide hydrolysis by phorbol esters through the activation of protein kinase C in differentiated human leukemia (HL-60) cells.
Topics: Cell Differentiation; Cell Line; Enzyme Activation; Humans; Inositol Phosphates; Leukemia, Experimental; N-Formylmethionine Leucyl-Phenylalanine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
Abolishment of inhibitory effects of 3'-deazaadenosine on superoxide generation of guinea pig phagocytes by pre-exposure to phorbol myristate acetate.
Topics: Animals; Antigen-Antibody Complex; Dose-Response Relationship, Drug; Guinea Pigs; Lectins; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytes; Phorbols; Ribonucleosides; Superoxides; Tetradecanoylphorbol Acetate; Tubercidin; Wheat Germ Agglutinins | 1986 |
Self-limitation of the oxidative burst of rat polymorphonuclear leukocytes.
Topics: Animals; Catalase; Chlortetracycline; Cytochromes; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
The inhibition of neutrophil responsiveness caused by phorbol esters is blocked by the protein kinase C inhibitor H7.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcium; Cytosol; Exocytosis; Hexosaminidases; Isoquinolines; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phorbols; Phosphoproteins; Piperazines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase.
Topics: Calpain; Cytochalasin B; Endopeptidases; Exocytosis; Humans; Hydrogen Peroxide; Leupeptins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Retinaldehyde; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Aberrant activation and regulation of the oxidative burst in neutrophils with Mol glycoprotein deficiency.
Topics: Cell Adhesion; Chemotaxis, Leukocyte; Glycoproteins; Humans; Infant; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Peroxidase; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
An in vitro model for polymorphonuclear-leukocyte-induced injury to an extracellular matrix. Relative contribution of oxidants and elastase to fibronectin release from amnionic membranes.
Topics: Amnion; Basement Membrane; Catalase; Extracellular Matrix; Fibronectins; Humans; In Vitro Techniques; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Cell alkalinization is not necessary and increased sodium influx is not sufficient for stimulated superoxide production.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Hydrogen-Ion Concentration; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase C; Rabbits; Sodium; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Modulation of the kinetics of induced neutrophil superoxide generation by fluoride.
Topics: Calcium; Fluorides; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Interactions of antirheumatic drugs with the superoxide generation system of activated human polymorphonuclear leukocytes.
Topics: Anti-Inflammatory Agents; Endopeptidases; Humans; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Serine Endopeptidases; Superoxides; Tetradecanoylphorbol Acetate; Tritium; Xanthine; Xanthine Oxidase; Xanthines | 1986 |
Deficiency of neutrophil membrane antigen detected by monoclonal antibody in rheumatoid arthritis.
Topics: Antibodies, Monoclonal; Antigens, Surface; Arthritis, Rheumatoid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Activation-dependent redistribution of cellular components alters susceptibility of human neutrophils to cross-linking agents.
Topics: Concanavalin A; Cross-Linking Reagents; Enzyme Activation; Humans; Lymphocyte Activation; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Effect of gold compounds on NADPH oxidase system of human neutrophils.
Topics: Auranofin; Aurothioglucose; Cytoplasmic Granules; Free Radicals; Gold; Gold Sodium Thiomalate; Humans; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Cell Membrane; Cell Survival; Cytochrome c Group; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Survival; Chloroquine; Fluorides; Humans; Hydroxychloroquine; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Neutrophil defect associated with malignant infantile osteopetrosis.
Topics: Flow Cytometry; Hematopoietic Stem Cells; Humans; Infant; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Osteopetrosis; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Anthrax toxin blocks priming of neutrophils by lipopolysaccharide and by muramyl dipeptide.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Antigens, Bacterial; Bacterial Toxins; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
The first seconds of neutrophil activation: phosphoinositides, protein kinase C, and calcium movements.
Topics: Calcium; Chemotaxis, Leukocyte; Drug Synergism; Ethers; Humans; Ionomycin; Kinetics; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Nicotine potentiates superoxide anion generation by human neutrophils.
Topics: Drug Synergism; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nicotine; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of neutrophil superoxide formation by 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7), and inhibitor of protein kinase-C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Cytoplasm; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Cytoplasmic pH regulation in activated human neutrophils: effects of adenosine and pertussis toxin on Na+/H+ exchange and metabolic acidification.
Topics: Adenosine; Biological Transport, Active; Carrier Proteins; Cell Aggregation; Cytoplasm; Enzyme Activation; Humans; Hydrogen; Hydrogen-Ion Concentration; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Pentose Phosphate Pathway; Pertussis Toxin; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Human GM-CSF primes neutrophils for enhanced oxidative metabolism in response to the major physiological chemoattractants.
Topics: Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Interleukin-3; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Engagement of adenosine receptors inhibits hydrogen peroxide (H2O2-) release by activated human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Antigen-Antibody Complex; Concanavalin A; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Intracellular pH changes during neutrophil activation: Na+/H+ antiport.
Topics: Amiloride; Humans; Hydrogen-Ion Concentration; Hypertonic Solutions; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymyxin B; Protein Kinase C; Protons; Sodium; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Comparison of the roles of calmodulin and protein kinase C in activation of the human neutrophil respiratory burst.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calmodulin; Humans; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Piperazines; Protein Kinase C; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
The leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites.
Topics: Arachidonic Acid; Arachidonic Acids; Humans; Immunoglobulin G; Leukotriene B4; Ligands; Linoleic Acid; Linoleic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Drug; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cell-Free System; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters.
Topics: Calcium; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases; Virulence Factors, Bordetella | 1987 |
The effect of a protein kinase C inhibitor, H-7, on human neutrophil oxidative burst and degranulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium-Binding Proteins; Cells, Cultured; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Thalidomide enhances superoxide anion release from human polymorphonuclear and mononuclear leukocytes.
Topics: Chemotaxis; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate; Thalidomide | 1986 |
Translocation of diacylglycerol kinase in response to chemotactic peptide and phorbol ester in neutrophils.
Topics: Cell Membrane; Chemotaxis, Leukocyte; Cytosol; Diacylglycerol Kinase; Diglycerides; Glycerides; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases; Tetradecanoylphorbol Acetate | 1987 |
The bioflavonoid quercetin inhibits neutrophil degranulation, superoxide production, and the phosphorylation of specific neutrophil proteins.
Topics: Adult; Blood Proteins; Cytoplasmic Granules; Flavonoids; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Quercetin; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Dynamics of chemotactic peptide-induced superoxide generation by human monocytes.
Topics: Adenosine; Cold Temperature; Humans; In Vitro Techniques; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
The effect of chlorhexidine on blood cells.
Topics: Chemotaxis, Leukocyte; Chlorhexidine; Erythrocytes; Humans; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Signalling for increased cytoskeletal actin in neutrophils.
Topics: Actins; Animals; Calcimycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Pertussis Toxin; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
A high-yield, high-purity elutriation method for preparing human granulocytes demonstrating enhanced experimental lifetimes.
Topics: Cell Separation; Cell Survival; Centrifugation; Granulocytes; Humans; Kinetics; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Enhanced chemotaxis and superoxide anion production by polymorphonuclear leukocytes from nicotine-treated and smoke-exposed rats.
Topics: Animals; Cell Survival; Chemotaxis, Leukocyte; Drug Synergism; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nicotine; Rats; Rats, Inbred Strains; Smoking; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Charge-dependent regulation of NADPH oxidase activity in guinea-pig polymorphonuclear leukocytes.
Topics: Amines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Membrane; Electrochemistry; Enzyme Activation; Guinea Pigs; Hydrocarbons; Intracellular Membranes; Male; Myristic Acid; Myristic Acids; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Eosinophil- and neutrophil-mediated injury of human lung fibroblast cells.
Topics: Animals; Catalase; Cell Communication; Cell Line; Cells, Cultured; Cytotoxicity, Immunologic; Eosinophils; Fibroblasts; Humans; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Influence of lysophospholipids and PAF on the oxidative burst of PMNL.
Topics: Acetophenones; Animals; Complement C5; Complement C5a; Female; Guinea Pigs; In Vitro Techniques; Luminescent Measurements; Lysophosphatidylcholines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Significance of phosphorylation/dephosphorylation of 46K protein(s) in regulation of superoxide anion production in intact guinea pig polymorphonuclear leukocytes.
Topics: Animals; Concanavalin A; Guinea Pigs; Isoelectric Point; Mannosides; Molecular Weight; Multienzyme Complexes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Phosphoproteins; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Monocyte interleukin 2 receptor gene expression and interleukin 2 augmentation of microbicidal activity.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Cytotoxicity, Immunologic; Gene Expression Regulation; Giardia; HLA-DR Antigens; Humans; Immunity, Cellular; Interleukin-2; Macrophage Activation; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Receptor-mediated O2- release by alveolar macrophages and peripheral blood monocytes from smokers and nonsmokers. Priming and triggering effects of monomeric IgG, concanavalin A, N-formyl-methionyl-leucyl-phenylalanine, phorbol myristate acetate, and cyto
Topics: Adult; Binding Sites; Concanavalin A; Cytochalasin D; Cytochalasins; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunoglobulin G; Macrophages; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pulmonary Alveoli; Receptors, Fc; Smoking; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Polyamines stimulate superoxide production in human neutrophils activated by N-fMet-Leu-Phe but not by phorbol myristate acetate.
Topics: Calcium; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Polyamines; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Restoration of Fc receptor-mediated desensitization of superoxide generation in human PMN by PMA.
Topics: Antigen-Antibody Complex; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Fc; Superoxides; Tetradecanoylphorbol Acetate; Tubercidin; Wheat Germ Agglutinins | 1987 |
The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process.
Topics: Ethers; Humans; Hydrogen Peroxide; Ionomycin; Kinetics; Leukotriene B4; Luminescent Measurements; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1987 |
Chemotactic factor binding and functional capacity: a comparison between human granulocytes and differentiated HL-60 cells.
Topics: Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Leukemia, Myeloid, Acute; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Peroxidase; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1987 |
Surface receptor mobilization in complement-mediated neutrophil activation: characterization and effects of methylprednisolone.
Topics: Complement System Proteins; Humans; Lymphocyte Activation; Methylprednisolone; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Respiratory Distress Syndrome; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Is a rise in intracellular concentration of free calcium necessary or sufficient for stimulated cytoskeletal-associated actin?
Topics: Actins; Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cytoskeletal Proteins; Cytoskeleton; Fluorescent Dyes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophils.
Topics: Biological Transport, Active; Calcimycin; Calcium; Cell Membrane; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Potentiation and inhibition of secretion from neutrophils by phorbol ester.
Topics: Animals; Calcimycin; Calcium; Cytoplasmic Granules; Exocytosis; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Role of extracellular calcium in neutrophil responsiveness to chemotactic tripeptides.
Topics: Calcimycin; Calcium; Extracellular Space; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1986 |
Gamma interferon is able to enhance the oxidative metabolism of human neutrophils.
Topics: Concanavalin A; Cycloheximide; Drug Synergism; Humans; In Vitro Techniques; Interferon-gamma; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1986 |
In vitro formation of activators for prostaglandin synthesis by neutrophils and macrophages from humans and guinea pigs.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Enzyme Activation; Glutathione Peroxidase; Guinea Pigs; HEPES; Humans; Hydrogen Peroxide; Leukotrienes; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Protamine sulfate-induced enzyme secretion from rabbit neutrophils.
Topics: Animals; Calcimycin; Exocytosis; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophils; Protamines; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
The generation of lipid peroxides by stimulated human neutrophils. Detection using phenol red oxidation.
Topics: Arachidonic Acids; Catalase; Enzyme Activation; Humans; Leukotrienes; Lipid Peroxides; Lipoxygenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Phenolphthaleins; Phenolsulfonphthalein; Tetradecanoylphorbol Acetate | 1987 |
Calcium ionophore, phorbol ester, and chemotactic peptide-induced cytoskeleton reorganization in human neutrophils.
Topics: Actins; Calcimycin; Calcium; Cytoskeleton; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Chemoattractant-induced activation of c-fos gene expression in human monocytes.
Topics: beta 2-Microglobulin; Cycloheximide; Dactinomycin; Gene Expression Regulation; GTP-Binding Proteins; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Protein Biosynthesis; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Virulence Factors, Bordetella | 1987 |
Signal response transduction in rabbit neutrophil leucocytes. The effects of exogenous phospholipase A2 suggest two pathways exist.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Luminescent Measurements; Lymphocyte Activation; Lysophosphatidylcholines; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Rabbits; Tetradecanoylphorbol Acetate | 1987 |
Phosphorylation and dephosphorylation of soluble proteins in human eosinophils.
Topics: Blood Proteins; Calcimycin; Eosinophils; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Solubility; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
[Effects of benzydamine on leukocyte aggregation].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzydamine; Calcimycin; Cell Aggregation; Cell Survival; Exudates and Transudates; In Vitro Techniques; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Pyrazoles; Rats; Tetradecanoylphorbol Acetate | 1987 |
Neutrophils are hyperpolarized after exudation and show an increased depolarization response to formyl-peptide but not to phorbol myristate acetate.
Topics: Animals; Exudates and Transudates; Female; Fluorescence; Guinea Pigs; Humans; In Vitro Techniques; Indicators and Reagents; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1987 |
The effect of apomorphine on exocytosis and metabolic burst of polymorphonuclear leukocytes.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Calcimycin; Exocytosis; In Vitro Techniques; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Rabbits; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 1987 |
Modulation of surface CD11/CD18 glycoproteins (Mo1, LFA-1, p150,95) by human mononuclear phagocytes.
Topics: Animals; Antigens, Differentiation; Antigens, Surface; Blood Proteins; Calcimycin; Humans; Lymphocyte Function-Associated Antigen-1; Macrophage Activation; Macrophage-1 Antigen; Macrophages; Membrane Glycoproteins; Milk; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1988 |
Demonstration of calcium-dependent phospholipase A2 activity in membrane preparation of rabbit neutrophils. Absence of activation by fMet-Leu-Phe, phorbol 12-myristate 13-acetate and A-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Membrane; Enzyme Activation; In Vitro Techniques; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of the chemotactic peptide-induced elevation of intracellular calcium in differentiated human leukemic (HL-60) cells by the phorbol ester phorbol 12-myristate 13-acetate.
Topics: Calcium; Cell Differentiation; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Inositol Phosphates; Leukemia, Myeloid, Acute; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1988 |
Adherence of human basophils to cultured umbilical vein endothelial cells.
Topics: Basophils; Calcimycin; Cations, Divalent; Cell Adhesion; Cell Line; Complement C5; Complement C5a; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1988 |
Enhancement of c-fos expression is associated with activated macrophages.
Topics: Animals; BCG Vaccine; Calcimycin; Calcitriol; Cell Line; DNA; Gene Expression Regulation; Hybrid Cells; Kinetics; Lipopolysaccharides; Lymphokines; Macrophage Activation; Macrophages; Mice; N-Formylmethionine Leucyl-Phenylalanine; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.
Topics: Calcimycin; Culture Media; Humans; In Vitro Techniques; Kinetics; Lipoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Effect of chemotactic factors on hexose transport in polymorphonuclear leucocytes.
Topics: 3-O-Methylglucose; Arachidonic Acid; Arachidonic Acids; Biological Transport; Blood; Calcimycin; Chemotactic Factors; Deoxyglucose; Glucose; Hexoses; Humans; Kinetics; Methylglucosides; Monosaccharide Transport Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombin; Zymosan | 1988 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Stimulation of release of prostaglandins and thromboxanes from isolated guinea pig lung cells by bradykinin, f-Met-Leu-Phe, phorbol myristate, ionophore A23187, and leukotrienes.
Topics: Animals; Bradykinin; Calcimycin; Dinoprostone; Guinea Pigs; In Vitro Techniques; Leukotrienes; Lung; N-Formylmethionine Leucyl-Phenylalanine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Cytoplasm; In Vitro Techniques; Isoquinolines; Lyngbya Toxins; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Piperazines; Plant Extracts; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Effects of preparative procedures and of cell activation on flow of white cells through micropore filters.
Topics: Anticoagulants; Culture Media; Edetic Acid; Granulocytes; Humans; Leukocytes; Leukocytes, Mononuclear; Micropore Filters; N-Formylmethionine Leucyl-Phenylalanine; Rheology; Specimen Handling; Tetradecanoylphorbol Acetate | 1988 |
PMA induces the ligand-independent internalization of CR1 on human neutrophils.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Membrane; Humans; Mice; Mice, Inbred BALB C; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phorbols; Rabbits; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate | 1985 |
Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.
Topics: Animals; Bacterial Toxins; GTP-Binding Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbol Esters; Phorbols; Phospholipids; Protein Kinase C; Protein Kinases; Rabbits; Sodium; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
The limitation of the human neutrophil chemiluminescence response by extracellular peroxidase is stimulus dependent: effect of added horse radish peroxidase on the response induced by both soluble and particulate stimuli.
Topics: Adult; Horseradish Peroxidase; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1988 |
Enhancement of phorbol ester-induced protein kinase activity in human neutrophils by platelet-activating factor.
Topics: Calcium; Cytochalasin B; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1988 |
Anti-immunoglobulin pretreatment induces a calcium-mobilization response to the chemotactic agent N-formylmethionylleucylphenylalanine in Daudi lymphoblastoid cells.
Topics: Antigen-Antibody Complex; Benzofurans; Calcium; Cell Line; Fura-2; Humans; Immunoglobulin G; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Signal Transduction; Tetradecanoylphorbol Acetate | 1988 |
Dihydrorhodamine 123: a new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes.
Topics: Flow Cytometry; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytosis; Rhodamines; Tetradecanoylphorbol Acetate; Xanthenes | 1988 |
Effect of neutrophil activating substances on intracellular generation of phagocyte chemiluminescence by means of luminol-bound microspheres.
Topics: Concanavalin A; Cytochalasin B; Granulocytes; Humans; Luminescent Measurements; Microscopy, Electron, Scanning; Microspheres; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Tetradecanoylphorbol Acetate | 1988 |
Lymphocyte-neutrophil interactions: opposite effects of interleukin-2 and tumour necrosis factor-beta (lymphotoxin) on human neutrophil adherence.
Topics: Cell Adhesion; Cell Communication; Dose-Response Relationship, Immunologic; Drug Synergism; Hot Temperature; Humans; Interleukin-2; Lymphocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymyxin B; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1988 |
Diclofenac binding to human polymorphonuclear neutrophils: effect on respiratory burst and N-formylated peptide binding.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Bactericidal Activity; Cold Temperature; Diclofenac; Hot Temperature; Humans; Klebsiella pneumoniae; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Tetradecanoylphorbol Acetate | 1987 |
Effect of ceftriaxone on bacterial killing by human neutrophils in vitro.
Topics: Ceftriaxone; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Klebsiella pneumoniae; Microbial Sensitivity Tests; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1987 |
Oxidant-mediated inhibition of ligand uptake by the macrophage mannose receptor.
Topics: Animals; Bone Marrow Cells; Catalase; Glucose Oxidase; Glucuronidase; Hydrogen Peroxide; Lectins, C-Type; Ligands; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Receptors, Cell Surface; Receptors, Immunologic; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1988 |
Detection of carriers of the autosomal form of chronic granulomatous disease.
Topics: Genetic Carrier Screening; Granulomatous Disease, Chronic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.
Topics: Chromosome Aberrations; Chromosome Disorders; Electrophoresis, Polyacrylamide Gel; Granulomatous Disease, Chronic; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Chemotactic factor induced tyrosine phosphorylation of membrane associated proteins in rabbit peritoneal neutrophils.
Topics: Animals; Kinetics; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1988 |
Relationship of protein phosphorylation to the activation of the respiratory burst in human neutrophils. Defects in the phosphorylation of a group of closely related 48-kDa proteins in two forms of chronic granulomatous disease.
Topics: Blood Proteins; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1988 |
Dual effect of thiopentone on human granulocyte activation. Non-intervention by ketamine and morphine.
Topics: Cell Aggregation; Humans; In Vitro Techniques; Ketamine; Morphine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiopental | 1988 |
Comparative study of assays for stimulated fluid pinocytosis in canine and human neutrophils.
Topics: Animals; Dogs; Flow Cytometry; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pinocytosis; Spectrometry, Fluorescence; Spectrum Analysis; Tetradecanoylphorbol Acetate | 1988 |
On the mechanisms of association of the macrolide antibiotic erythromycin with isolated human polymorphonuclear leucocytes.
Topics: Biological Transport; Blood Proteins; Cell Membrane; Cytoplasm; Erythromycin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Temperature; Tetradecanoylphorbol Acetate | 1988 |
Charge-dependent regulation of NADPH oxidase activities in intact and subcellular systems of polymorphonuclear leukocytes.
Topics: Animals; Cell-Free System; Guinea Pigs; Interphase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphorylation; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1988 |
Threshold responses in production of reactive oxygen metabolites in individual neutrophils detected by flow cytometry and microfluorimetry.
Topics: Cells, Cultured; Flow Cytometry; Fluoresceins; Humans; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1987 |
Effect of phorbol myristate acetate and the chemotactic peptide fNLPNTL on shape and movement of human neutrophils.
Topics: Chemotaxis, Leukocyte; Humans; Microscopy, Interference; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1987 |
Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells.
Topics: 2,3-Diphosphoglycerate; Calcium; Cell Differentiation; Cell Line; Cell Membrane; Diphosphoglyceric Acids; Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Leukemia, Myeloid, Acute; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1987 |
Tissue-specific phosphorylation of complement receptors CR1 and CR2.
Topics: B-Lymphocytes; Eosinophils; Humans; In Vitro Techniques; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Receptors, Complement; Tetradecanoylphorbol Acetate | 1986 |
The effects of phorbol myristate acetate and chemotactic peptide on transmembrane potentials and cytosolic free calcium in mature granulocytes evolve sequentially as the cells differentiate.
Topics: Aminoquinolines; Benzothiazoles; Bone Marrow Cells; Calcium; Carbocyanines; Cell Differentiation; Cell Membrane; Cytosol; Fluorescent Dyes; Granulocytes; Hematopoietic Stem Cells; Humans; Hydrogen-Ion Concentration; Interleukin-3; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Potassium; Sodium; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Macrophage-neutrophil interactions: contrasting effects of the monokines interleukin-1 and tumour necrosis factor (cachectin) on human neutrophil adherence.
Topics: Dose-Response Relationship, Immunologic; Humans; Immune Adherence Reaction; Interleukin-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymyxin B; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
Cell surface expression of fMet-Leu-Phe receptors on human neutrophils. Correlation to changes in the cytosolic free Ca2+ level and action of phorbol myristate acetate.
Topics: Aminoquinolines; Calcium; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1987 |
Uptake of 3H-deoxyglucose as a microassay of human neutrophil and monocyte activation.
Topics: Cell Count; Deoxy Sugars; Deoxyglucose; Dose-Response Relationship, Drug; Humans; Macrophage Activation; Microchemistry; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Potassium Cyanide; Tetradecanoylphorbol Acetate; Time Factors; Tritium | 1987 |
Priming of the respiratory burst of neutrophils by diacylglycerol. Independence from activation or translocation of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cytosol; Diglycerides; Enzyme Activation; Glycerides; Humans; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Differences and similarities between human and rabbit neutrophil granulocyte responses in vitro: the effects of zymosan-activated plasma, phorbol myristate acetate and n-formyl-methionyl-leucyl-phenylalanine.
Topics: Animals; Cell Aggregation; Granulocytes; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Plasma; Rabbits; Species Specificity; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Comparison of in vivo effects of intravenous infusion of N-formyl-methionyl-leucyl-phenylalanine and phorbol myristate acetate in rabbits.
Topics: Animals; Blood Pressure; Granulocytes; Infusions, Intravenous; Kinetics; Leukocyte Count; N-Formylmethionine Leucyl-Phenylalanine; Rabbits; Respiration; Tetradecanoylphorbol Acetate | 1987 |
Prostaglandin E1 inhibits N-formyl-methionyl-leucyl-phenylalanine-mediated depolarization responses by decreasing the proportion of responsive cells without affecting chemotaxin-induced forward light scatter changes.
Topics: Alprostadil; Cytochalasin B; Humans; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Nephelometry and Turbidimetry; Neutrophils; Tetradecanoylphorbol Acetate | 1987 |
Differentiation of cellular processes involved in the induction and maintenance of stimulated neutrophil adherence.
Topics: Cell Adhesion; Cell Differentiation; Cytochalasin B; Ethylmaleimide; Humans; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
A step sensitive to pertussis toxin and phorbol ester in human neutrophils regulates chemotaxis and capping but not phagocytosis.
Topics: Chemotaxis, Leukocyte; Concanavalin A; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phagocytosis; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Age-related decline in ligand-induced actin polymerization in human leukocytes and platelets.
Topics: Actins; Adult; Aged; Aging; Blood Platelets; Female; Humans; In Vitro Techniques; Ligands; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenylephrine; Tetradecanoylphorbol Acetate; Triiodothyronine | 1986 |
Phosphorylation of proteins in human neutrophils activated with phorbol myristate acetate or with chemotactic factor.
Topics: Blood Proteins; Cell Membrane; Cytosol; Electrophoresis, Polyacrylamide Gel; Humans; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
The role of the cytosolic free Ca2+ transient for fMet-Leu-Phe induced actin polymerization in human neutrophils.
Topics: Actin Cytoskeleton; Actins; Calcium; Cells, Cultured; Chemotaxis, Leukocyte; Cytoskeleton; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Monitoring human neutrophil granule secretion by flow cytometry: secretion and membrane potential changes assessed by light scatter and a fluorescent probe of membrane potential.
Topics: Cytochalasin B; Cytoplasmic Granules; Exocytosis; Flow Cytometry; Humans; Light; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Scattering, Radiation; Tetradecanoylphorbol Acetate | 1985 |
Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation.
Topics: Calcium; Cell Line; Cytoplasmic Granules; Ethers; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Ionomycin; Leukemia, Myeloid, Acute; Lymphocyte Activation; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophages.
Topics: Calcimycin; Cells, Cultured; Humans; Kinetics; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; SRS-A; Tetradecanoylphorbol Acetate | 1985 |
Independent stimulation of membrane potential changes and the oxidative metabolic burst in polymorphonuclear leukocytes.
Topics: Carbocyanines; Flow Cytometry; Humans; Hydrogen Peroxide; In Vitro Techniques; Membrane Potentials; Microscopy, Fluorescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1985 |
Effects of soluble stimuli on human monocyte secretion.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetylglucosaminidase; Cycloheximide; Dipeptides; Gallic Acid; Humans; Monocytes; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Chemotactic factor binding by metastatic tumour cells: evidence for a formyl-peptide receptor on a non-myelogenous cell.
Topics: Animals; Binding Sites; Carcinoma 256, Walker; Cell Adhesion; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Protein Binding; Rats; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Phorbol myristate acetate enhances human polymorphonuclear neutrophil release of granular enzymes but inhibits chemokinesis.
Topics: Calcium; Chemotaxis, Leukocyte; Cytoplasm; Cytoplasmic Granules; Glucuronidase; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
The role of C-kinase in the physiological activation of the neutrophil oxidase. Evidence from using pharmacological manipulation of C-kinase activity in intact cells.
Topics: Animals; Diglycerides; Diterpenes; Enzyme Activation; In Vitro Techniques; Latex; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Phorbols; Protein Kinase C; Rats; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigen-Antibody Complex; Antioxidants; Calcimycin; Catechols; Cyclooxygenase Inhibitors; Cytochalasin B; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Pyrazoles; Pyrazolones; Rats; Superoxides; Tetradecanoylphorbol Acetate; Thiazines; Zymosan | 1984 |
Mechanisms of regulating the respiratory burst in leukocytes.
Topics: Animals; Arachidonic Acids; Calcimycin; Calcium; Cytoplasmic Granules; Electric Conductivity; Granulomatous Disease, Chronic; Humans; Leukocytes; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nucleotides, Cyclic; Oxygen Consumption; Peroxidase; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Mobilization and adaptation of human neutrophil chemoattractant fMet-Leu-Phe receptors.
Topics: Chemotaxis, Leukocyte; Cytoplasmic Granules; Humans; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Tetradecanoylphorbol Acetate | 1984 |
Regulatory mechanisms of a chemoattractant receptor on leukocytes.
Topics: Amphotericin B; Chemotaxis, Leukocyte; Guanine Nucleotides; Humans; Kinetics; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Various authentic chemoattractants mediating leukocyte adherence inhibition.
Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Complement C5a, des-Arginine; Humans; Leukocyte Adherence Inhibition Test; Leukocytes; Leukotriene B4; Liver Neoplasms; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Effect of anti-inflammatory drugs on leukocyte superoxide production by soluble and particulate stimuli.
Topics: Anti-Inflammatory Agents; Concanavalin A; Digitonin; Humans; Indomethacin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1984 |
[Indomethacin and oxamethacin as modulators of the production of superoxide anion in human leukocytes].
Topics: Humans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1984 |
Phosphorylation of cytosolic proteins by resting and activated human neutrophils.
Topics: Cytosol; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleotides, Cyclic; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1984 |
A new physiological function for adenosine: regulation of superoxide anion production.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Anions; Calcimycin; Concanavalin A; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Association of leukotriene B4 with the cytoskeleton of rabbit neutrophils. Effect of chemotactic factor and phorbol esters.
Topics: Animals; Cytoskeleton; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phorbols; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.
Topics: Calcium; Cycloheximide; Humans; Hydrogen Peroxide; In Vitro Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Oxygen Consumption; Superoxides; Temperature; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Bee venom inhibits superoxide production by human neutrophils.
Topics: Bee Venoms; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1984 |
Inhibitory effects of various drugs on phorbol myristate acetate and n-formyl methionyl leucyl phenylalanine induced O2- production in polymorphonuclear leukocytes.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Abnormal distribution of complex carbohydrates in neutrophils of a patient with lactoferrin deficiency.
Topics: Acid Phosphatase; Alkaline Phosphatase; Carbohydrates; Cytoplasmic Granules; Humans; Lactoferrin; Lactoglobulins; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidases; Staining and Labeling; Sulfates; Tetradecanoylphorbol Acetate | 1983 |
Role of phospholipase A2 activation in histamine release from human basophils.
Topics: Acetophenones; Basophils; Calcimycin; Histamine Release; Humans; Melitten; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1983 |
Auranofin, an oral chrysotherapeutic agent, inhibits histamine release from human basophils.
Topics: Asthma; Auranofin; Aurothioglucose; Basophils; Calcimycin; Gold; Gold Sodium Thiomalate; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1984 |
Transmembrane potential changes associated with superoxide release from human granulocytes.
Topics: Calcimycin; Calcium; Concanavalin A; Granulocytes; Humans; Membrane Potentials; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Potassium; Sodium; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Respiratory burst enzyme in human neutrophils. Evidence for multiple mechanisms of activation.
Topics: Benzenesulfonates; Calcimycin; Concanavalin A; Diazonium Compounds; Enzyme Activation; Fluorides; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADP; Neutrophils; Oligopeptides; Oxygen Consumption; Sulfanilic Acids; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Chemotactic factor enhancement of superoxide release from fluoride and phorbol myristate acetate stimulated neutrophils.
Topics: Chemotactic Factors; Enzyme Activation; Fluorides; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Humans; In Vitro Techniques; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Polymorphonuclear leucocyte membrane-stimulated oxidative metabolic activity---the effect of divalent cations and cytochalasins.
Topics: Adult; Calcium; Cell Membrane; Cells, Cultured; Cytochalasins; Cytochrome c Group; Digitonin; Dose-Response Relationship, Drug; Humans; Luminescent Measurements; Magnesium; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen Consumption; Tetradecanoylphorbol Acetate; Zymosan | 1981 |
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity.
Topics: 1-Butanol; Butanols; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cycloheximide; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Lactoferrin; Methionine; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pinocytosis; Puromycin; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Evidence for 5, 12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation.
Topics: Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Kinetics; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1981 |
Dexamethasone synergistically induces chemotactic peptide receptor expression in HL-60 cells.
Topics: Cell Line; Cell Transformation, Neoplastic; Dexamethasone; Dimethyl Sulfoxide; Dimethylformamide; Dose-Response Relationship, Drug; Drug Synergism; Humans; Indomethacin; Methionine; Methyltestosterone; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Progesterone; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Chemotactic factor inactivation by stimulated human neutrophils mediated by myeloperoxidase-catalyzed methionine oxidation.
Topics: Aminopeptidases; Candidiasis; Catalysis; Chemotactic Factors; Complement C5; Complement C5a; Granulomatous Disease, Chronic; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Sulfides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Dissociation by piroxicam of degranulation and superoxide anion generation from decrements in chlortetracycline fluorescence of activated human neutrophils.
Topics: Analgesics; Cell Aggregation; Chemotactic Factors; Chlortetracycline; Concanavalin A; Humans; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen; Piroxicam; Pyridines; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate; Thiazines | 1982 |
Modulation of polymorphonuclear leukocyte chemiluminescent response to the chemoattractant f-Met-Leu-Phe.
Topics: Chemotactic Factors; Humans; Luminescent Measurements; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Saccharomyces cerevisiae; Temperature; Tetradecanoylphorbol Acetate | 1982 |
A rapid densitometric microassay for nitroblue tetrazolium reduction and application of the microassay to macrophages.
Topics: Animals; Calcimycin; Concanavalin A; Cytochrome c Group; Densitometry; Guinea Pigs; Macrophages; Microscopy; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oligopeptides; Oxidation-Reduction; Photometry; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1981 |
Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: studies with cells from normals and patients with chronic granulomatous disease.
Topics: Adult; Calcimycin; Cells, Cultured; Female; Granulomatous Disease, Chronic; Humans; Infant; Macrophages; Male; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Opsonin Proteins; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
The effect of various stimuli and calcium antagonists on the fluorescence response of chlorotetracycline-loaded human neutrophils.
Topics: Calcium; Chlortetracycline; Concanavalin A; Egtazic Acid; Gallic Acid; Glucuronidase; Humans; Lysosomes; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phorbols; Spectrometry, Fluorescence; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine; Vasodilator Agents | 1982 |
Release of gelatinase from a novel secretory compartment of human neutrophils.
Topics: Calcimycin; Carrier Proteins; Cell Compartmentation; Cells, Cultured; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Gelatinases; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pepsin A; Superoxides; Tetradecanoylphorbol Acetate; Vitamin B 12 | 1982 |
Differences in superoxide production by nonmigrating and migrating human monocyte subpopulations.
Topics: Cell Movement; Chemotaxis; Humans; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Regulation of neutrophil inflammatory mediator release: chemotactic peptide activation of stimulus-dependent cytotoxicity.
Topics: Chemotactic Factors; Chromium Radioisotopes; Cytotoxicity, Immunologic; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Inflammation; Interleukin-8; Male; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Tetradecanoylphorbol Acetate | 1983 |
Modulation of granulocyte response to the chemoattractant F-Met-Leu-Phe.
Topics: Chemotaxis, Leukocyte; Granulocytes; Humans; Kinetics; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Tetradecanoylphorbol Acetate | 1982 |
Role of myeloperoxidase in luminol-dependent chemiluminescence of polymorphonuclear leukocytes.
Topics: Cytochalasin B; Humans; Luminescent Measurements; Luminol; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Pyridazines; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Identification of ubiquinone-50 as the major methylated nonpolar lipid in human monocytes. Regulation of its biosynthesis via methionine-dependent pathways and relationship to superoxide production.
Topics: Animals; Cell Line; Chemotaxis, Leukocyte; Chromatography, Thin Layer; Coenzymes; Humans; Kinetics; Methionine; Methylation; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Tritium; Ubiquinone | 1983 |
Exposure of human neutrophils to chemotactic factors potentiates activation of the respiratory burst enzyme.
Topics: Chemotactic Factors; Complement C5; Complement C5a; Cytoplasmic Granules; Deoxycholic Acid; Dose-Response Relationship, Immunologic; Enzyme Activation; Humans; Interleukin-8; Kinetics; Luminescent Measurements; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neutrophils; Oligopeptides; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Changes in phosphatidylinositol and phosphatidic acid in stimulated human neutrophils. Relationship to calcium mobilization, aggregation and superoxide radical generation.
Topics: Calcium; Cell Aggregation; Free Radicals; Humans; In Vitro Techniques; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphatidic Acids; Phosphatidylinositols; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Prostaglandin E1 and prostaglandin I2 modulation of superoxide production by human neutrophils.
Topics: Alprostadil; Arachidonic Acid; Arachidonic Acids; Epoprostenol; Humans; In Vitro Techniques; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen; Prostaglandins; Prostaglandins E, Synthetic; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Human neutrophils contain an intracellular pool of putative receptors for the chemoattractant N-formyl-methionyl-leucyl-phenylalanine.
Topics: Binding Sites; Cell Membrane; Cytoplasmic Granules; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Receptors, Amino Acid; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1983 |
Selective defect in human neutrophil superoxide anion generation elicited by the chemoattractant N-formylmethionylleucylphenylalanine in pregnancy.
Topics: Chemotaxis, Leukocyte; Estradiol; Female; Humans; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen; Pregnancy; Progesterone; Receptors, Fc; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Regulation of monocyte oxidative metabolism: chemotactic factor enhancement of superoxide release, hydroxyl radical generation, and chemiluminescence.
Topics: Adult; Chemotactic Factors; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Oxygen; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of neutrophil activation by alpha1-acid glycoprotein.
Topics: Cell Aggregation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Orosomucoid; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Myeloperoxidase modulates the phagocytic activity of polymorphonuclear neutrophil leukocytes. Studies with cells from a myeloperoxidase-deficient patient.
Topics: Complement C3b; Humans; Immunoglobulin G; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peroxidase; Peroxidases; Phagocytosis; Psoriasis; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Superoxide production of human polymorphonuclear leukocytes stimulated by leukotriene B4.
Topics: Animals; Anions; Calcium; Calcium Channel Blockers; Calmodulin; Cytochalasin B; Dose-Response Relationship, Drug; Gallic Acid; Guinea Pigs; Humans; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Reversible blockade of the respiratory burst in human neutrophils by a cleavable cross-linking agent.
Topics: Cross-Linking Reagents; Dithiothreitol; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Succinimides; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Quantitative and temporal characterization of the extracellular H2O2 pool generated by human neutrophils.
Topics: Catalase; Extracellular Space; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Stimulus response coupling in the human neutrophil. I. Kinetic analysis of changes in calcium permeability.
Topics: Antigen-Antibody Complex; Biological Transport, Active; Calcium; Cell Membrane Permeability; Chemotaxis, Leukocyte; Concanavalin A; Cytochalasin B; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Serum Albumin, Bovine; Superoxides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1984 |
The respiratory burst of human neutrophils treated with various stimulators in vitro is dampened by exogenous unsaturated fatty acids.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Calcium; Cyclic AMP; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Fluorides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Tetradecanoylphorbol Acetate | 1984 |
Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production.
Topics: Acetylglucosaminidase; Animals; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cyclic AMP; Cytochalasin B; Dose-Response Relationship, Drug; Epoprostenol; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Rabbits; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1984 |
Activation of the oxidative burst in human monocytes is associated with inhibition of methionine-dependent methylation of neutral lipids and phospholipids.
Topics: Calcimycin; Catalase; Cell Movement; Cytochrome c Group; Humans; Kinetics; Lipids; Methionine; Methylation; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Phospholipids; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Organelle-depleted human neutrophil cytoplasts used to study fmet-leu-phe receptor modulation and cell function.
Topics: Carbocyanines; Cell Aggregation; Chemotaxis, Leukocyte; Cytoplasmic Granules; Electrophoresis; Humans; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organoids; Receptors, Cell Surface; Receptors, Formyl Peptide; Tetradecanoylphorbol Acetate | 1984 |
Intra- and extracellular events in luminol-dependent chemiluminescence of polymorphonuclear leukocytes.
Topics: Humans; Hydrogen Peroxide; Kinetics; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Pyridazines; Serum Albumin; Tetradecanoylphorbol Acetate | 1984 |
Prostaglandin modulation of N-formylmethionylleucylphenylalanine-induced transmembrane potential changes in rat neutrophils.
Topics: Alprostadil; Animals; Bucladesine; Cyclic AMP; Epoprostenol; Female; Isoproterenol; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Tetradecanoylphorbol Acetate | 1984 |
Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.
Topics: Calcimycin; Chemotactic Factors; Complement C5; Complement C5a; Cytochalasin B; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Kinetics; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate | 1983 |
Effects of non-steroidal anti-inflammatory agents on human neutrophil functions in vitro and in vivo.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Anti-Inflammatory Agents; Chlortetracycline; Concanavalin A; Humans; Ibuprofen; In Vitro Techniques; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals.
Topics: Calcimycin; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.
Topics: Animals; Blood Proteins; Calcimycin; Carcinogens; Cytochalasin B; Kinetics; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate; Trifluoperazine | 1984 |
Localization of histaminase to the specific granule of the human neutrophil.
Topics: Amine Oxidase (Copper-Containing); Calcimycin; Cell Fractionation; Centrifugation, Density Gradient; Concanavalin A; Cytochalasin B; Cytoplasmic Granules; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
Diacylglycerols enhance human neutrophil degranulation responses: relevancy to a multiple mediator hypothesis of cell function.
Topics: Animals; Calcimycin; Cytoplasmic Granules; Diglycerides; Glycerides; Humans; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
A comparison of the effects of soluble stimuli on free cytoplasmic and membrane bound calcium in human neutrophils.
Topics: Adult; Aminoquinolines; Calcimycin; Calcium; Cytochalasin B; Cytoplasm; Fluorescent Dyes; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
Chemotactic peptide enhancement of PMA triggered monocyte cytotoxicity.
Topics: Cytotoxicity, Immunologic; Drug Synergism; Humans; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Changes in ascorbate levels on stimulation of human neutrophils.
Topics: Ascorbic Acid; Cytochalasin B; Dehydroascorbic Acid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Tumor promoter-induced centrosome splitting in human polymorphonuclear leukocytes.
Topics: Carcinogens; Humans; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organoids; Tetradecanoylphorbol Acetate | 1983 |
A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture.
Topics: Animals; Calcimycin; Cells, Cultured; Colorimetry; Concanavalin A; Guinea Pigs; Hydrogen Peroxide; Lectins; Macrophages; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Phenolsulfonphthalein; Tetradecanoylphorbol Acetate; Zymosan | 1980 |
Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA.
Topics: Calcimycin; Chemotactic Factors; Humans; Kinetics; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
Endogenous protein phosphorylation by resting and activated human neutrophils.
Topics: Digitonin; Granulomatous Disease, Chronic; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Mechanisms of lysosomal enzyme secretion by human U-937 monocytes.
Topics: Acetylglucosaminidase; Ammonium Chloride; Cell Line; Cytochalasin B; Hexosaminidases; Humans; Lymphokines; Lysosomes; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Phagocytosis; Tetradecanoylphorbol Acetate | 1983 |
Mechanism of dexamethasone inhibition of chemotactic factor induced granulocyte aggregation.
Topics: Cell Aggregation; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Dexamethasone; Endothelium; Glucuronidase; Granulocytes; Humans; In Vitro Techniques; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Tetradecanoylphorbol Acetate | 1982 |
Generation of hydrogen peroxide by human neutrophils: effects of soluble stimuli and requirements for divalent cations.
Topics: Calcium; Cytochalasin B; Dipeptides; Humans; Hydrogen Peroxide; In Vitro Techniques; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate; Trifluoperazine | 1982 |
Influenza A virus-induced polymorphonuclear leukocyte dysfunction.
Topics: Humans; Influenza A virus; Luminescent Measurements; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Oxygen Consumption; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1982 |
The fluorescence response of chlorotetracycline-loaded human neutrophils. Correlations with lysosomal enzyme release and evidence for a 'trigger pool' of calcium.
Topics: Binding Sites; Calcium; Cell Membrane; Chlortetracycline; Glucuronidase; Humans; Lysosomes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1982 |
Chemotaxis of metastatic tumor cells.
Topics: Animals; Carcinoma 256, Walker; Cell Adhesion; Cells, Cultured; Chemotactic Factors; Chemotaxis; Kinetics; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Oligopeptides; Tetradecanoylphorbol Acetate | 1982 |
Lactoferrin: a promoter of polymorphonuclear leukocyte adhesiveness.
Topics: Animals; Cell Adhesion; Cell Aggregation; Cytoplasmic Granules; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Lactoferrin; Lactoglobulins; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Rabbits; Tetradecanoylphorbol Acetate | 1981 |
Surface-reactive stimuli selectively increase protein phosphorylation in human neutrophils.
Topics: Adult; Chemotaxis, Leukocyte; Electrophoresis, Polyacrylamide Gel; Humans; Methionine; Molecular Weight; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phorbols; Phosphates; Phosphorylation; Tetradecanoylphorbol Acetate | 1981 |
The onset of polymorphonuclear leucocyte membrane-stimulated metabolic activity.
Topics: Antimetabolites; Cell Membrane; Cytochalasin B; Digitonin; Humans; Luminescent Measurements; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1981 |
Human neutrophil heterogeneity identified using flow microfluorometry to monitor membrane potential.
Topics: Calcium; Cell Membrane; Flow Cytometry; Granulomatous Disease, Chronic; Humans; Magnesium; Membrane Potentials; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate | 1981 |
Ligands of purinergic receptors stimulate electrogenic H(+)-transport of neutrophils.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Kinetics; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Proton-Translocating ATPases; Purinergic P2 Receptor Agonists; Ribonucleotides; Swine; Tetradecanoylphorbol Acetate | 1995 |
Beta 2 integrin engagement triggers actin polymerization and phosphatidylinositol trisphosphate formation in non-adherent human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Actin Cytoskeleton; Actins; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Cyclic AMP; Humans; In Vitro Techniques; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Phosphates; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Graded changes in the response of individual human basophils to stimulation: distributional behavior of early activation events.
Topics: Basophils; Calcium; Cell Degranulation; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1994 |
Pharmacological investigations with different protein kinase C inhibitors on IgE-dependent and IgE-independent activation of human basophils.
Topics: Alkaloids; Basophils; Calcimycin; Exocytosis; Histamine; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptors, IgE; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H1-antagonist, desethoxycarbonyl-loratadine.
Topics: Basophils; Calcimycin; Concanavalin A; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Loratadine; N-Formylmethionine Leucyl-Phenylalanine; Rhinitis, Allergic, Seasonal; Tetradecanoylphorbol Acetate | 1994 |
Identification of IgE-bearing cells in the late-phase response to antigen in the lung as basophils.
Topics: Alcian Blue; Allergens; Antibodies, Anti-Idiotypic; Antigens, Surface; Basophils; Bronchoalveolar Lavage Fluid; Dimaprit; Histamine; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; Lung; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1994 |
Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils.
Topics: Antigens, CD; Calcimycin; Calcium; CD18 Antigens; Cell Adhesion Molecules; Down-Regulation; Endopeptidases; Humans; Interleukin-8; L-Selectin; Leukosialin; Macrophage-1 Antigen; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protease Inhibitors; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1994 |
Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin.
Topics: Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Cell Adhesion Molecules; Cell Line; Cell Membrane; Humans; L-Selectin; Lymphocytes; Membrane Glycoproteins; Mice; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phytohemagglutinins; Rats; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Dynamic state of beta 2 integrin phosphorylation: regulation of neutrophil aggregation involves a phosphatase-dependent pathway.
Topics: Adult; Amino Acid Sequence; Antigens, CD; CD18 Antigens; Cell Aggregation; Cell Survival; Ethers, Cyclic; Humans; Integrins; Kinetics; L-Lactate Dehydrogenase; Macromolecular Substances; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate | 1994 |
Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells.
Topics: Bucladesine; Cadmium; Calcium; Cations; Fluorescent Dyes; Fura-2; Gadolinium; Humans; Imidazoles; Ion Channels; Manganese; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Oxocins; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1994 |
Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils.
Topics: Amino Acid Sequence; Antibodies; CD18 Antigens; Cell Adhesion; Enzyme Activation; Epitopes; Humans; Integrins; Kinetics; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 1994 |
The active monomeric form of macrophage inflammatory protein-1 alpha interacts with high- and low-affinity classes of receptors on human hematopoietic cells.
Topics: Antigens, CD; Antigens, CD34; Binding, Competitive; Chemokine CCL4; Cross-Linking Reagents; Cytokines; Granulocytes; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia; Macrophage Inflammatory Proteins; Molecular Weight; Monocytes; Monokines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Chemokine; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Lipopolysaccharide primes human basophils for enhanced mediator release: requirement for plasma co-factor and CD14.
Topics: Acute-Phase Proteins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Basophils; Calcimycin; Carrier Proteins; Histamine Release; Humans; Immunoglobulin E; Kinetics; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1994 |
Inhibition by FK506 of formyl peptide-induced neutrophil activation and associated protein synthesis.
Topics: Calcium; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Protein Biosynthesis; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tacrolimus; Tetradecanoylphorbol Acetate | 1994 |
Investigations with the selective PKC inhibitor chelerythrine on human basophils.
Topics: Alkaloids; Basophils; Benzophenanthridines; Calcimycin; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Alterations in expression of p56lck during myeloid differentiation of LSTRA cells.
Topics: Antigens, Differentiation; Bucladesine; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Cycle; Cell Differentiation; Cholecalciferol; Enzyme Induction; Granulocytes; Hematopoietic Stem Cells; Histocompatibility Antigens Class II; Humans; Leukemia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1994 |
Modulation of rat neutrophil functions by administration of granulocyte colony-stimulating factor.
Topics: Amino Acid Sequence; Animals; Ascitic Fluid; Buffers; Cell Adhesion; Cell Division; Granulocyte Colony-Stimulating Factor; Male; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
In vitro effects of oxidized low density lipoprotein on CD11b/CD18 and L-selectin presentation on neutrophils and monocytes with relevance for the in vivo situation.
Topics: 1-Butanol; Adult; Animals; Butanols; CD18 Antigens; Cell Adhesion Molecules; Cells, Cultured; Cricetinae; Female; Flow Cytometry; Fluorescence Polarization; Humans; L-Selectin; Lipoproteins, LDL; Macrophage-1 Antigen; Male; Mesocricetus; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1995 |
Activation of NADPH-oxidase and its associated whole-cell H+ current in human neutrophils by recombinant human tumor necrosis factor alpha and formyl-methionyl-leucyl-phenylalanine.
Topics: Amino Acid Sequence; Benzopyrans; Cell Membrane; Cytosol; Enzyme Activation; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Naphthols; Neutrophils; Protons; Recombinant Proteins; Rhodamines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Regulation of L-selectin expression by membrane proximal proteolysis.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Cell Adhesion Molecules; Cell Membrane; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Humans; Immunosorbent Techniques; L-Selectin; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protease Inhibitors; Sequence Homology; Tetradecanoylphorbol Acetate | 1995 |
Administration of rHuGM-CSF activates monocyte reactive oxygen species secretion and adhesion molecule expression in vivo in patients following high-dose chemotherapy.
Topics: Adult; Antigens, Bacterial; CD18 Antigens; Cell Adhesion Molecules; Cyclophosphamide; Escherichia coli; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; L-Selectin; Lipopolysaccharides; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Recombinant Proteins; Respiratory Burst; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1995 |
Decreased activation of the respiratory burst in neutrophils from AIDS patients with previous Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Case-Control Studies; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Seronegativity; HIV Seropositivity; Humans; Kinetics; Leukocyte Count; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Pneumocystis; Pneumonia, Pneumocystis; Rats; Recombinant Proteins; Respiratory Burst; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1995 |
Graded changes in the response of individual human basophils to stimulation: distributional behavior of events temporally coincident with degranulation.
Topics: Acridine Orange; Antigens, CD; Basophils; Cytoplasmic Granules; Flow Cytometry; Histamine Release; Humans; Immunoglobulin E; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Platelet Membrane Glycoproteins; Scattering, Radiation; Tetradecanoylphorbol Acetate; Tetraspanin 30 | 1995 |
ADP-ribosylation factor translocation correlates with potentiation of GTP gamma S-stimulated phospholipase D activity in membrane fractions of HL-60 cells.
Topics: ADP-Ribosylation Factors; Carcinogens; Carrier Proteins; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
Cyclic AMP-increasing agents interfere with chemoattractant-induced respiratory burst in neutrophils as a result of the inhibition of phosphatidylinositol 3-kinase rather than receptor-operated Ca2+ influx.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Biological Transport, Active; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Local anesthetics enhance nitric oxide production by human peripheral neutrophils.
Topics: Anesthetics, Local; Blood Pressure; Bupivacaine; Canavanine; Dibucaine; Humans; In Vitro Techniques; Lidocaine; Mepivacaine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1995 |
Selective inhibition of human TNF-alpha action by flecainide acetate, an antiarrhythmic drug.
Topics: Animals; Anti-Arrhythmia Agents; Cell Survival; Dose-Response Relationship, Drug; Flecainide; Humans; In Vitro Techniques; L Cells; Membrane Potentials; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphotyrosine; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
CD66 family members are associated with tyrosine kinase activity in human neutrophils.
Topics: Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate | 1995 |
Influence of nifedipine on plasma membrane fluidity and oxidative burst of polymorphonuclear leucocytes.
Topics: Fluorescence Polarization; Humans; In Vitro Techniques; Luminescent Measurements; Lymphocytes; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1995 |
NPC 15669-modulated human polymorphonuclear neutrophil functional responsiveness: effects on receptor-coupled signal transduction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Dose-Response Relationship, Drug; Exocytosis; Humans; Leucine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Modulation of neutrophil function by novel colonic factors: possible role in the pathophysiology of ulcerative colitis.
Topics: Adult; Aged; Colitis, Ulcerative; Colon; Dialysis; Female; Humans; Luminescent Measurements; Luminol; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rectum; Tetradecanoylphorbol Acetate | 1995 |
Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors.
Topics: Adenosine Triphosphate; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophil Activation; Neutrophils; p21-Activated Kinases; Pertussis Toxin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1995 |
The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes.
Topics: Calcium; Cell Membrane; Centrifugation, Density Gradient; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukocytes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1995 |
Mineral fiber-induced leukocyte activation: the role of intra- and extracellular calcium.
Topics: Asbestos, Serpentine; Calcimycin; Calcium; Cell Survival; Dose-Response Relationship, Drug; Egtazic Acid; Fura-2; Humans; Luminescent Measurements; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quartz; Reactive Oxygen Species; Respiratory Burst; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Verapamil | 1995 |
Redistribution of protein kinase C isoforms in human neutrophils stimulated by formyl peptides and phorbol myristate acetate.
Topics: Blotting, Western; Calcium; Cell Membrane; Cytosol; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1995 |
Differential induction of stress proteins and functional effects of heat shock in human phagocytes.
Topics: Cadmium; Cadmium Compounds; Erythrocytes; Gene Expression Regulation; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phagocytosis; Platelet Activating Factor; Respiratory Burst; Staphylococcus aureus; Sulfates; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1995 |
Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phosphate d
Topics: Animals; Bucladesine; Cell Membrane Permeability; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Digitonin; Epinephrine; Glucose; Glucosephosphate Dehydrogenase; Glutamine; Glycerol; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Malate Dehydrogenase; Male; Mycobacterium bovis; N-Formylmethionine Leucyl-Phenylalanine; NADP; Oxygen Consumption; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1995 |
Relationship between resazurin reduction test, reactive oxygen species generation, and gamma-glutamyltransferase.
Topics: gamma-Glutamyltransferase; Horseradish Peroxidase; Humans; In Vitro Techniques; Indicators and Reagents; Infertility, Male; Lipid Peroxidation; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxazines; Oxidation-Reduction; Oxidative Stress; Prostate; Reactive Oxygen Species; Spermatozoa; Tetradecanoylphorbol Acetate; Xanthenes | 1995 |
An inhibitor of cyclic AMP-dependent protein kinase enhances the superoxide production of human neutrophils stimulated by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Bucladesine; Calcium; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Signal Transduction; Sodium Dodecyl Sulfate; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung: involvement of ETA and ETB receptors.
Topics: Animals; Azepines; Blood Pressure; Bosentan; Bronchopulmonary Sequestration; Capillary Permeability; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; In Vitro Techniques; Indoles; Injections, Intravenous; Lung; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Peptide Fragments; Plasma Volume; Platelet Activating Factor; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Potentiation of the respiratory burst of human neutrophils by cycloheximide: regulation of reactive oxidant production by a protein(s) with rapid turnover?
Topics: Amino Acid Sequence; Calcium; Cycloheximide; Drug Synergism; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukotriene B4; Luminescent Measurements; Luminol; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Puromycin; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of neutrophil oxidative metabolism by trichinellosis patient sera. Parasite origin or host induction?
Topics: Animals; Antibodies, Helminth; Humans; Interleukin-2; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Trichinella spiralis; Trichinellosis | 1995 |
A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; CHO Cells; Cricetinae; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrinogen; Humans; Immunoglobulin Fab Fragments; Intercellular Adhesion Molecule-1; Interleukin-8; Kinetics; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Leukocyte-Adhesion; Temperature; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Release of platelet activation factor from activated neutrophils. Transglutaminase-dependent enhancement of transbilayer movement across the plasma membrane.
Topics: Cell Membrane; Cystamine; Erythrocyte Membrane; Humans; In Vitro Techniques; Ionomycin; Kinetics; Lipid Bilayers; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sarcosine; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Transglutaminases | 1993 |
Factor-specific changes in oxidative burst response of human neutrophils in skin-window exudates.
Topics: Concanavalin A; Exudates and Transudates; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Respiratory Burst; Skin Window Technique; Sodium Fluoride; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1993 |
CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes.
Topics: Antibodies, Monoclonal; Antigens, CD; Cell Adhesion Molecules; Cells, Cultured; Complement C5a; Electrophoresis, Polyacrylamide Gel; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; Kinetics; L-Selectin; Leukocytes; Leukosialin; Lymphocytes; Membrane Glycoproteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Recombinant Proteins; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Granulocyte colony-stimulating factor enhances the extracellular emission of reactive oxygen from neutrophils stimulated with formylmethionylleucylphenylalanine.
Topics: Cytochalasin B; Drug Synergism; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Influence of a pentoxifylline-analogue on the granulocyte-mediated pulmonary mediator release and vascular reaction.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Female; Histamine Release; Lung; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Pulmonary Artery; Rabbits; Tetradecanoylphorbol Acetate; Thromboxane B2; Vascular Resistance | 1993 |
Effect of indomethacin and aspirin on the TNF-alpha-induced priming and protein tyrosyl phosphorylation of human neutrophils.
Topics: Animals; Aspirin; Azides; Electrophoresis, Polyacrylamide Gel; Granulocyte Colony-Stimulating Factor; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sodium Azide; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Tyrosine | 1993 |
Chemiluminescence of neutrophils in patients with myeloproliferative or myelodysplastic hematologic diseases--relation to neutrophil alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Cells, Cultured; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Luminescent Measurements; Myelodysplastic Syndromes; Myeloproliferative Disorders; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombocythemia, Essential | 1993 |
Stimulation of human basophils results in homotypic aggregation. A response independent of degranulation.
Topics: Alkaloids; Antibodies, Monoclonal; Antigens, CD; Basophils; CD18 Antigens; Cell Aggregation; Cell Degranulation; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Farnesyl thiotriazole, a potent neutrophil agonist and structurally novel activator of protein kinase C.
Topics: Animals; Diglycerides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Farnesol; Guinea Pigs; In Vitro Techniques; Kinetics; Models, Molecular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphoproteins; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1995 |
The chemiluminescence response of neutrophils on polymer surfaces made by glow discharge plasma polymerization.
Topics: Acrylates; Biocompatible Materials; Cyclohexylamines; Humans; Luminescent Measurements; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Polymers; Serum Albumin; Siloxanes; Surface Properties; Tetradecanoylphorbol Acetate | 1994 |
Nitric oxide reduces hydrogen peroxide production from human polymorphonuclear neutrophils.
Topics: Collagen; Humans; Hydrogen Peroxide; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; Potassium Cyanide; Respiratory Burst; Tetradecanoylphorbol Acetate | 1995 |
Neutrophil deactivation by influenza A virus. Role of hemagglutinin binding to specific sialic acid-bearing cellular proteins.
Topics: Antigens, CD; Antigens, Surface; Calcium; Concanavalin A; Granulocyte-Macrophage Colony-Stimulating Factor; Hemagglutinins, Viral; Humans; Hydrogen Peroxide; Immunity, Cellular; In Vitro Techniques; Influenza A virus; Leukocyte Elastase; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Receptors, Virus; Sialic Acids; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Receptor-independent mechanisms are involved in the priming of neutrophil's oxidase by vasoactive intestinal peptide.
Topics: Calcimycin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Receptors, Vasoactive Intestinal Peptide; Respiratory Burst; Somatostatin; Sphingosine; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1994 |
Superoxide generation by guinea-pig peritoneal macrophages is inhibited by rolipram, staurosporine and mepacrine in an agonist-dependent manner.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Macrophages, Peritoneal; Male; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Platelet Activating Factor; Protein Kinase C; Pyrrolidinones; Quinacrine; Respiratory Burst; Rolipram; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Role of gelsolin in the formation and organization of triton-soluble F-actin during myeloid differentiation of HL-60 cells.
Topics: Actins; Biopolymers; Cell Compartmentation; Cell Differentiation; Chemotaxis, Leukocyte; Contractile Proteins; Cytoskeleton; Dimethyl Sulfoxide; Filamins; Gelsolin; Humans; Leukemia, Promyelocytic, Acute; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Octoxynol; Respiratory Burst; Solubility; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Contrasting effects of calyculin A and okadaic acid on the respiratory burst of human neutrophils.
Topics: Amino Acid Sequence; Calcimycin; Ethers, Cyclic; Humans; In Vitro Techniques; Marine Toxins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Evidence for participation of vicinal dithiols in the activation sequence of the respiratory burst of human neutrophils.
Topics: Arachidonic Acid; Arsenicals; Blood Proteins; Calcium; Cell-Free System; Cytosol; Dimercaprol; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Respiratory Burst; Signal Transduction; Sulfhydryl Compounds; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Crosstalk in signal transduction via EP receptors: prostaglandin E1 inhibits chemoattractant-induced mitogen-activated protein kinase activity in human neutrophils.
Topics: Adenosine Triphosphate; Alprostadil; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Prostaglandin E; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells.
Topics: Azepines; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Triazoles; Umbilical Veins; Virulence Factors, Bordetella | 1995 |
Modulation of phorbol ester-induced respiratory burst by vanadate, genistein, and phenylarsine oxide in mouse macrophages.
Topics: Animals; Arsenicals; Genistein; Isoflavones; Macrophages, Peritoneal; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Translocation of p21rac2 from cytosol to plasma membrane is neither necessary nor sufficient for neutrophil NADPH oxidase activity.
Topics: Cell Fractionation; Cell Membrane; Cell-Free System; Cytosol; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; Tetradecanoylphorbol Acetate | 1995 |
Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils.
Topics: Androstadienes; Animals; Chromones; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Protamine Kinase; Protein Denaturation; Protein Kinase Inhibitors; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 1995 |
Differences in the effects of two hexa-chlorophenols on superoxide generation by polymorphonuclear leucocytes stimulated by N-formyl-methionyl-leucyl-phenylalanine and phorbol myristate acetate.
Topics: Chlorophenols; Glycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
The role of G-proteins in the activation of human leukocytes by particulate stimuli to produce reactive oxygen metabolites.
Topics: Adult; Asbestos, Serpentine; Calcium; Cholera Toxin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pertussis Toxin; Quartz; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1995 |
Phosphatidylcholine turnover in activated human neutrophils. Agonist-induced cytidylyltransferase translocation is subsequent to phospholipase D activation.
Topics: Biological Transport; Catalysis; Choline; Choline-Phosphate Cytidylyltransferase; Cytochalasin B; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nucleotidyltransferases; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1995 |
Age-associated changes of neutrophil responsiveness in a human healthy elderly population.
Topics: Adult; Aged; Aged, 80 and over; Aging; Chemotaxis, Leukocyte; Cytotoxicity, Immunologic; Female; Humans; Leukocyte Count; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Effects of a protein kinase C inhibitor, Ro 31-7549, on the activation of human leukocytes by particulate stimuli.
Topics: Adult; Asbestos, Serpentine; Calcium; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Protein Kinase C; Quartz; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1995 |
Dissociation of mitogen-activated protein kinase activation from the oxidative burst in differentiated HL-60 cells and human neutrophils.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Nimesulide decreases superoxide production by inhibiting phosphodiesterase type IV.
Topics: Adenylyl Cyclases; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cell Membrane; Chemotaxis, Leukocyte; Cyclic AMP; Humans; In Vitro Techniques; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Oxygen Consumption; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase Inhibitors; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Effects of low-density lipoproteins on polymorphonuclear leukocyte functions in vitro.
Topics: Alkaloids; Amino Acid Sequence; Cell Survival; Chemotaxis, Leukocyte; Complement C5a; Humans; Leukocyte Migration-Inhibitory Factors; Lipoproteins, LDL; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Staurosporine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
Ibudilast, an anti-allergic and cerebral vasodilator, modulates superoxide production in human neutrophils.
Topics: Calcium; Cyclic AMP; Humans; Inositol 1,4,5-Trisphosphate; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyridines; Superoxides; Tetradecanoylphorbol Acetate; Vasodilator Agents | 1995 |
Induction of neutrophil Mac-1 integrin expression and superoxide production by the medicinal plant extract gossypol.
Topics: Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cells, Cultured; Edetic Acid; Enzyme Induction; Gene Expression Regulation; Gossypol; Humans; Intracellular Fluid; Macrophage-1 Antigen; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Staurosporine; Stereoisomerism; Structure-Activity Relationship; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
NADPH-oxidase activity of stimulated neutrophils is markedly increased by serum.
Topics: Adenosine Triphosphate; Adult; Animals; Blood Physiological Phenomena; Cattle; Dose-Response Relationship, Drug; Glycolysis; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Opsonin Proteins; Oxidation-Reduction; Protein Synthesis Inhibitors; Respiratory Burst; Serum Albumin, Bovine; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Polymorphonuclear leukocytes-induced injury in hypoxic cardiac myocytes.
Topics: Animals; Catalase; Cell Hypoxia; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Mice; Microscopy, Electron; Myocardium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Thiobarbiturates; Zymosan | 1994 |
The effects of recombinant human granulocyte-macrophage colony stimulating factor on the neutrophil respiratory burst in the term and preterm infant when studied in whole blood.
Topics: Adult; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Infant, Newborn; Infant, Premature; Intensive Care, Neonatal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Reference Values; Respiratory Burst; Tetradecanoylphorbol Acetate | 1994 |
Comparison of properties of membrane bound versus soluble forms of human leukocytic elastase and cathepsin G.
Topics: alpha 1-Antitrypsin; Amino Acid Sequence; Cathepsin G; Cathepsins; Cell Membrane; Cytoplasmic Granules; Histones; Humans; Leukocyte Elastase; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peroxidase; Protamines; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium Chloride; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of superoxide production in human neutrophils by combinations of heparin and thrombolytic agents.
Topics: Depression, Chemical; Drug Synergism; Fibrinolytic Agents; Heparin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Streptokinase; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator; Zymosan | 1995 |
Cromolyn inhibits assembly of the NADPH oxidase and superoxide anion generation by human neutrophils.
Topics: Adult; Amino Acid Sequence; Calcium; Cell Degranulation; Cromolyn Sodium; Fura-2; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Protein Kinase C; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Methyl mercury, mercuric chloride, and silver lactate decrease superoxide anion formation and chemotaxis in human polymorphonuclear leucocytes.
Topics: Cell Survival; Chemotaxis, Leukocyte; Humans; In Vitro Techniques; Lactates; Lactic Acid; Mercuric Chloride; Methylmercury Compounds; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.
Topics: Animals; Antigen-Antibody Complex; Cathepsin G; Cathepsins; Cytochalasin B; Enzyme Precursors; Gelatinases; Humans; Leukocyte Elastase; Lung Diseases; Male; Metalloendopeptidases; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Neutrophils; Oxidants; Pancreatic Elastase; Proteinase Inhibitory Proteins, Secretory; Proteins; Pulmonary Alveoli; Rats; Recombinant Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2 | 1993 |
Dual effects of formylpeptides on the adhesion of endotoxin-primed human neutrophils.
Topics: Antigens, CD; CD11 Antigens; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Endotoxins; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Regulation of CD18 expression in human neutrophils as related to shape changes.
Topics: Amino Acid Sequence; Antigens, CD; CD18 Antigens; Cell Movement; Cell Size; Chemotactic Factors; Ethers, Cyclic; Humans; In Vitro Techniques; Indoles; Marine Toxins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oligopeptides; Oxazoles; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate | 1993 |
Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium.
Topics: Antigens, CD; Calcimycin; CD11 Antigens; CD18 Antigens; Cells, Cultured; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipids; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate; Umbilical Veins | 1994 |
Regulation of C1q receptor expression on human polymorphonuclear leukocytes.
Topics: Carrier Proteins; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paclitaxel; Receptors, Complement; Receptors, Complement 3b; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
Parallel up-regulation of CD11B and CD45 on neutrophilic leukocytes exposed to soluble factors of oral pathogens.
Topics: Antigens, CD; Bacteria; CD11 Antigens; Flow Cytometry; Humans; Leukocyte Common Antigens; Mouth; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Up-Regulation | 1994 |
Identification of a subgroup of myelodysplastic patients with a neutrophil stimulation-signalling defect.
Topics: Blood Bactericidal Activity; Calcium; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Luminescent Measurements; Myelodysplastic Syndromes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine.
Topics: Animals; Arachidonic Acid; Arginine; Free Radicals; Hydroxyl Radical; Luminescent Measurements; Luminol; Male; Malondialdehyde; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
S-thiolation of glyceraldehyde-3-phosphate dehydrogenase induced by the phagocytosis-associated respiratory burst in blood monocytes.
Topics: Ethylmaleimide; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Respiratory Burst; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 1994 |
Priming of the oxidative burst in human neutrophils by physiological agonists or cytochalasin B results from the recruitment of previously non-responsive cells.
Topics: Cells, Cultured; Cytochalasin B; Cytokines; Fluorides; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Determinants of neutrophil HOCl generation: ligand-dependent responses and the role of surface adhesion.
Topics: Cell Adhesion; Cell Membrane; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Quantification and morphologic demonstration of reactive oxygen species produced by Walker 256 tumor cells in vitro and during metastasis in vivo.
Topics: Animals; Carcinoma 256, Walker; Cell Adhesion; Endothelium, Vascular; Hydrogen Peroxide; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Leukocyte-induced acute endothelial dysfunction in middle cerebral artery in rabbits. Response to aggregating platelets.
Topics: Animals; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Ischemic Attack, Transient; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Osmolar Concentration; Platelet Aggregation; Rabbits; Tetradecanoylphorbol Acetate; Time Factors; Vasodilator Agents | 1994 |
Staurosporine and its derivatives enhance f-Met-Leu-Phe-induced superoxide production via phospholipase D activation in human polymorphonuclear leukocytes.
Topics: Alkaloids; Amino Acid Sequence; Carbazoles; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Humans; Indole Alkaloids; Male; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Propranolol; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Determination of the rate of superoxide generation from biological systems by spin trapping: use of rapid oxygen depletion to measure the decay rate of spin adducts.
Topics: Cyclic N-Oxides; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Humans; Hypoxanthine; Hypoxanthines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1994 |
Long chain acyl coenzyme A and signaling in neutrophils. An inhibitor of acyl coenzyme A synthetase, triacsin C, inhibits superoxide anion generation and degranulation by human neutrophils.
Topics: Acyl Coenzyme A; Coenzyme A Ligases; Cytochalasin B; Cytoplasmic Granules; Humans; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazenes | 1994 |
Studies of neutrophil and monocyte oxidative responses in polycythaemia vera and related myeloproliferative disorders.
Topics: Adult; Aged; Humans; Hydrogen Peroxide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Luminescent Measurements; Middle Aged; Monocytes; Myeloproliferative Disorders; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polycythemia Vera; Tetradecanoylphorbol Acetate; Thrombocythemia, Essential | 1994 |
Cytokines stimulate lipid membrane peroxidation of human sperm.
Topics: Cell Membrane; Cytokines; Humans; Interleukins; Lipid Metabolism; Male; N-Formylmethionine Leucyl-Phenylalanine; Peroxides; Spermatozoa; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Flow cytometric assays of oxidative burst activity in phagocytes.
Topics: Cell Separation; Cell-Free System; Centrifugation, Density Gradient; Chemotaxis, Leukocyte; Ficoll; Flow Cytometry; Fluorescent Antibody Technique; Fluorescent Dyes; Horseradish Peroxidase; Humans; Indicators and Reagents; Leukocytes; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Phagocytes; Rhodamines; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Interferon-gamma enhances monocyte cytotoxicity via enhanced reactive oxygen intermediate production. Absence of an effect on macrophage cytotoxicity is due to failure to enhance reactive nitrogen intermediate production.
Topics: Acridines; Cells, Cultured; Chromates; Cytotoxicity, Immunologic; Humans; Interferon-gamma; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nitrites; Oxygen; Reactive Oxygen Species; Sodium Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inappropriate neutrophil activation in venous disease.
Topics: Aged; Arm; Calcium; Female; Free Radicals; Humans; Leg; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Regional Blood Flow; Scleroderma, Localized; Tetradecanoylphorbol Acetate; Varicose Ulcer; Venous Pressure | 1994 |
Priming effect of hydroxyapatite on the chemiluminescence response in human polymorphonuclear leukocytes.
Topics: Calcimycin; Dose-Response Relationship, Drug; Durapatite; Humans; Inflammation; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1994 |
[Effect of osmolarity of the medium on the chemiluminescence of human neutrophils].
Topics: Calcimycin; Hot Temperature; Humans; Immunoglobulin G; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Oxygen; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Rat brain microglia and peritoneal macrophages show similar responses to respiratory burst stimulants.
Topics: Animals; Macrophages, Peritoneal; Male; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Oxygen Consumption; Rats; Rats, Wistar; Respiratory Burst; Tetradecanoylphorbol Acetate; Tuftsin | 1994 |
Maturational changes in superoxide anion production of rabbit alveolar macrophages.
Topics: Aging; Animals; Cells, Cultured; Endothelins; Imidazoles; Luminescent Measurements; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Pyrazines; Rabbits; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
A sensitive detection of neutrophil activation by fluorescence quenching of membrane inserted singlet oxygen probe.
Topics: Benzofurans; Biphenyl Compounds; Cell Membrane; Cyclohexane Monoterpenes; Hydroxyl Radical; Monoterpenes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Onium Compounds; Oxygen; Photochemistry; Platelet Activating Factor; Singlet Oxygen; Spectrometry, Fluorescence; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
Stimulation of oxidant generation by human sperm suspensions using phorbol esters and formyl peptides: relationships with motility and fertilization in vitro.
Topics: Fertilization; Fertilization in Vitro; Humans; Leukocytes; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate | 1994 |
Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils.
Topics: Antibodies; Blotting, Western; Carrier Proteins; Cell Differentiation; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Complement; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1994 |
Separation of agonist-stimulated arachidonate mobilization from subsequent leukotriene B4 synthesis in human neutrophils: different effects of oleoylacetylglycerol and phorbol myristate acetate as priming agents.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arachidonic Acid; Biological Transport; Calcimycin; Diglycerides; Eicosanoids; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Tetradecanoylphorbol Acetate | 1994 |
Calcium overload toxicity and functional impairment in peritoneal leukocytes elicited by glycogen or interleukin-1 beta.
Topics: Animals; Calcimycin; Calcium; Drug Synergism; Glucuronidase; Glycogen; Humans; Injections, Intraperitoneal; Interleukin-1; L-Lactate Dehydrogenase; Leukocytes; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases.
Topics: Amino Acid Sequence; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peptide Mapping; Phosphorylation; Phosphoserine; Proline-Directed Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate | 1994 |
Does protein kinase C regulate receptor agonists-mediated elevation in the cytosolic Ca2+ in human neutrophils?
Topics: Alkaloids; Calcium; Cytosol; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Effect of inhibitors of distinct signalling pathways on neutrophil Q2- generation in response to tumor necrosis factor-alpha, and antibodies against CD18 and CD11a: evidence for a common and unique pattern of sensitivity to wortmannin and protein tyrosine
Topics: Alkaloids; Androstadienes; Antigens, CD; CD18 Antigens; Genistein; Integrins; Isoflavones; Lymphocyte Function-Associated Antigen-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella; Wortmannin | 1993 |
Phorbol ester-induced degranulation in adherent human eosinophil granulocytes is dependent on CD11/CD18 leukocyte integrins.
Topics: Antibodies; Antigens, CD; Blood Proteins; Calcimycin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Degranulation; Chelating Agents; Cytochalasin B; Egtazic Acid; Eosinophil Granule Proteins; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Interleukin-3; Ionomycin; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Phorbol Esters; Protein Kinase C; Ribonucleases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Evidence for integrins other than beta 2 on polymorphonuclear neutrophils: expression of alpha 6 beta 1 heterodimer.
Topics: Antibodies, Monoclonal; Antigens, CD; CD11 Antigens; CD18 Antigens; Cells, Cultured; Extracellular Matrix Proteins; Flow Cytometry; Fluorescent Antibody Technique; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunohistochemistry; Integrin alpha6beta1; Integrins; Interferon-gamma; Lymphotoxin-alpha; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Precipitin Tests; Radioimmunoassay; Receptors, Laminin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1993 |
Effect of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes.
Topics: Aminosalicylic Acids; Calcium; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Mesalamine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfapyridine; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes.
Topics: Antigens, CD; Base Sequence; CD11 Antigens; Cell Adhesion; Cell Differentiation; Dimethyl Sulfoxide; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NF-kappa B; Oligonucleotides, Antisense; Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Corticotropin-releasing hormone enhances the superoxide anion production of rabbit peritoneal macrophages stimulated with N-formyl-methionyl-leucyl-phenylalanine.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Female; Macrophages, Peritoneal; N-Formylmethionine Leucyl-Phenylalanine; Rabbits; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation.
Topics: Calcimycin; Calcium; Cell Aggregation; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
The small GTP-binding protein rac is not recruited to the plasma membrane upon NADPH oxidase activation in human neutrophils.
Topics: Cell Adhesion; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fluorescent Antibody Technique; GTP-Binding Proteins; Humans; In Vitro Techniques; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; rac GTP-Binding Proteins; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Neutrophil function after exposure to polychlorinated biphenyls in vitro.
Topics: Animals; Glucuronidase; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Desensitization by protein kinase C activation differentially uncouples formyl peptide receptors from effector enzymes in HL-60 granulocytes.
Topics: Autoradiography; Calcium; Cell Line; Enzyme Activation; Granulocytes; GTP-Binding Proteins; Leukotriene B4; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Phosphorylation; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Tetradecanoylphorbol Acetate | 1993 |
Cefdinir (CI-983), a new oral amino-2-thiazolyl cephalosporin, inhibits human neutrophil myeloperoxidase in the extracellular medium but not the phagolysosome.
Topics: Blood Bactericidal Activity; Calcimycin; Cefdinir; Cell Degranulation; Cephalosporins; Cytochalasin B; Extracellular Space; Humans; Hydrogen Peroxide; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Phagosomes; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil.
Topics: Benzoquinones; Cell Line; Chemotactic Factors; Complement C5a; Humans; In Vitro Techniques; Interleukin-8; Lactams, Macrocyclic; Leukotriene B4; Models, Biological; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Quinones; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Interferon-gamma corrects the respiratory burst defect in vitro in monocyte-derived macrophages from glycogen storage disease type 1b patients.
Topics: Adolescent; Adult; Cell Differentiation; Cells, Cultured; Child; Child, Preschool; Concanavalin A; Female; Glycogen Storage Disease Type I; Humans; Interferon-gamma; Macrophages; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate | 1993 |
Chemoattractant capacity of bombesin, gastrin-releasing peptide and neuromedin C is mediated through PKC activation in murine peritoneal leukocytes.
Topics: Analysis of Variance; Animals; Bombesin; Chemotaxis; Chemotaxis, Leukocyte; Enzyme Activation; Gastrin-Releasing Peptide; Lymphocytes; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Peptide Fragments; Peptides; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Normal oxidative activity and chemotaxis of circulating neutrophils in patients treated with photopheresis.
Topics: Adult; Aged; Chemotaxis, Leukocyte; Female; Humans; In Vitro Techniques; Male; Methoxsalen; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Photopheresis; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.
Topics: Amino Acid Sequence; Biological Transport; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine Triphosphate; Humans; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; rac GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor.
Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Gel; Chromatography, Ion Exchange; Complement C5a; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-8; Isoenzymes; Leukotriene B4; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Platelet Activating Factor; Point Mutation; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Rapid modification of ribosomal S6 kinase II (S6KII) in rabbit peritoneal neutrophils stimulated with chemotactic factor fMet-Leu-Phe.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Protein Serine-Threonine Kinases; Rabbits; Ribosomal Protein S6 Kinases; Tetradecanoylphorbol Acetate | 1994 |
Regulation of TNF-alpha receptor expression on human neutrophils by various cell activating factors.
Topics: Complement C5a; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Enhancement of polymorphonuclear leukocyte (PMN) function by OK-432.
Topics: Candida albicans; Carcinoma, Squamous Cell; Combined Modality Therapy; Cytokines; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Luminescent Measurements; Mouth Neoplasms; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Phagocytosis; Picibanil; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Increase in cell responses and protein phosphorylation of neutrophils induced by synthetic diacylglycerols.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azides; Blood Proteins; Brain; Diglycerides; Guinea Pigs; Isoquinolines; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Rats; Sodium Azide; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Monocyte dysfunction in patients with Gaucher disease: evidence for interference of glucocerebroside with superoxide generation.
Topics: Adult; Aged; Chemotaxis; Female; Gaucher Disease; Glucosylceramides; Granulocytes; Humans; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitroblue Tetrazolium; Opsonin Proteins; Oxidation-Reduction; Phagocytes; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Nitric oxide production by human peripheral blood polymorphonuclear leucocytes.
Topics: Humans; Interferon-gamma; Interleukin-6; Lipopolysaccharides; Methemoglobin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Oxyhemoglobins; Spectrophotometry; Stimulation, Chemical; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1994 |
Influence of suspension on the oxidative burst by rat neutrophils.
Topics: Animals; Body Weight; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Sprague-Dawley; Respiratory Burst; Space Flight; Superoxides; Tetradecanoylphorbol Acetate; Weightlessness | 1994 |
N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions.
Topics: Carbazoles; Enzyme Activation; Humans; In Vitro Techniques; Indoles; Isoenzymes; Maleimides; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of NADPH-oxidase activity in human polymorphonuclear neutrophils by lipophilic ascorbic acid derivatives.
Topics: Amino Acid Sequence; Arachidonic Acid; Ascorbic Acid; Calcium; Guanine Nucleotides; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Fc alpha R expression on polymorphonuclear leukocyte and superoxide generation in IgA nephropathy.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Female; Flow Cytometry; Glomerulonephritis; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Fc; Receptors, IgG; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Differences in the effects of two hexachlorobiphenyls on superoxide generation by polymorphonuclear leucocytes stimulated by N-formyl-methionyl-leucyl-phenylalanine and phorbol myristate acetate.
Topics: Animals; Cytochrome c Group; Dose-Response Relationship, Drug; Guinea Pigs; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polychlorinated Biphenyls; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1994 |
Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils.
Topics: Chromatography, High Pressure Liquid; Cysteine; Humans; In Vitro Techniques; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Increased respiratory burst activity is associated with normal expression of IgG-Fc-receptors and complement receptors in peripheral neutrophils from patients with juvenile periodontitis.
Topics: Adolescent; Adult; Aggressive Periodontitis; Case-Control Studies; Female; Humans; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Complement; Receptors, IgG; Receptors, Immunologic; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Suppressive effect of sera from patients undergoing chronic hemodialysis on neutrophil chemiluminescence response.
Topics: Female; Humans; Luminescent Measurements; Lymphocyte Activation; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Renal Dialysis; Respiratory Burst; Tetradecanoylphorbol Acetate; Uremia | 1993 |
Cytosolic protein phosphatase may turn off activated NADPH oxidase in guinea pig neutrophils.
Topics: Animals; Cytosol; Enzyme Activation; Ethers, Cyclic; Female; Guinea Pigs; Kinetics; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Effects of flavonoids on the release of reactive oxygen species by stimulated human neutrophils. Multivariate analysis of structure-activity relationships (SAR).
Topics: Acridines; Benzopyrans; Drug Design; Flavonoids; Glycosylation; Horseradish Peroxidase; Humans; Luminescent Measurements; Luminol; Multivariate Analysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
Topics: Concanavalin A; Genistein; Humans; Hydroquinones; Ionomycin; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1993 |
Stimulation of the human neutrophil respiratory burst by formyl peptides is primed by a protein kinase inhibitor, staurosporine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Genistein; Humans; Isoflavones; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Respiratory Burst; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.
Topics: Alkaloids; Amino Acid Sequence; Animals; Antigens; Cells, Cultured; Complement C5a; Humans; Kinetics; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Inhibition by the protein kinase inhibitor HA1077 of the activation of NADPH oxidase in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Enzyme Activation; Free Radicals; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate | 1993 |
Regulation of human neutrophil aggregation: comparable latent times, activator sensitivities, and exponential decay in aggregability for FMLP, platelet-activating factor, and leukotriene B4.
Topics: Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
A novel ecto-phosphatidic acid phosphohydrolase activity mediates activation of neutrophil superoxide generation by exogenous phosphatidic acid.
Topics: Animals; CHO Cells; Cricetinae; Ethylmaleimide; Humans; In Vitro Techniques; Kinetics; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organophosphonates; Phosphatidate Phosphatase; Phosphatidic Acids; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
The effects of GM-CSF on myeloperoxidase release in normal and myelodysplastic neutrophils.
Topics: Anemia; Cytochalasin B; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Leukemia, Myelomonocytic, Chronic; Luminescent Measurements; Myelodysplastic Syndromes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Recombinant Proteins; Reference Values; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Effect of phorbol myristate acetate on cerebral blood flow in normal and neutrophil-depleted rats.
Topics: Animals; Cerebrovascular Circulation; Endothelium, Vascular; Enzyme Activation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Count; Protein Kinase C; Rats; Rats, Wistar; Regional Blood Flow; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Volume-dependent regulation of the respiratory burst of activated human neutrophils.
Topics: Adult; Calcimycin; Humans; Hydrogen Peroxide; Hydroxyl Radical; Immunoglobulin G; In Vitro Techniques; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Oxygen; Photochemistry; Singlet Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements.
Topics: Biological Transport; Calcium; Cell Line; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; N-Formylmethionine Leucyl-Phenylalanine; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides | 1993 |
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.
Topics: Androstadienes; Autoradiography; Humans; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphates; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipase D; Phospholipids; Phosphorus Radioisotopes; Phosphotransferases (Alcohol Group Acceptor); Tetradecanoylphorbol Acetate; Wortmannin | 1993 |
Activation of NADPH oxidase of human neutrophils involves the phosphorylation and the translocation of cytosolic p67phox.
Topics: Cytosol; Enzyme Activation; Granulomatous Disease, Chronic; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Reference Values; Tetradecanoylphorbol Acetate | 1993 |
Activation of phosphatidylinositol 4,5-bisphosphate supply by agonists and non-hydrolysable GTP analogues.
Topics: Cell Membrane Permeability; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Kinetics; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphatidylinositol Phosphates; Phosphorus Radioisotopes; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Evidence for priming and activation of neutrophils early after coronary angioplasty.
Topics: Angioplasty, Balloon, Coronary; Cell Adhesion; Complement System Proteins; Humans; Lactoferrin; Leukocyte Count; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Protein kinase C regulates IL-8 and fMLP induced cytoplasmic Ca2+ increase in human granulocytes by receptor modulation measurements by flow cytometry.
Topics: Alkaloids; Aniline Compounds; Calcium; Cytoplasm; Diglycerides; Flow Cytometry; Fluorescent Dyes; Granulocytes; Humans; In Vitro Techniques; Interleukin-8; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Xanthenes | 1993 |
Sublethal doses of exogenous hydrogen peroxide prime human neutrophils to formyl peptide.
Topics: Centrifugation, Density Gradient; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Perioperative changes in superoxide production in neonates and infants.
Topics: Abdomen; Anesthesia, Inhalation; Female; Halothane; Humans; Infant; Infant, Newborn; Intraoperative Period; Leukocyte Count; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrous Oxide; Oxygen; Oxygen Consumption; Postoperative Period; Prospective Studies; Sensitivity and Specificity; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Cefodizime enhances formyl-methionyl-leucyl-phenylalanine-induced hydrogen peroxide production from human neutrophils.
Topics: Cefotaxime; Drug Synergism; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1993 |
The receptor for urokinase-type plasminogen activator and urokinase is translocated from two distinct intracellular compartments to the plasma membrane on stimulation of human neutrophils.
Topics: Biological Transport; Cell Fractionation; Cell Membrane; Fibrinolysin; Flow Cytometry; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
LDL modification by activated polymorphonuclear leukocytes: a cellular model of mild oxidative stress.
Topics: Humans; Lipopolysaccharides; Lipoproteins, LDL; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxidation-Reduction; Reactive Oxygen Species; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Zymosan | 1994 |
Activation of a voltage-dependent chloride current in human neutrophils by phorbol 12-myristate 13-acetate and formyl-methionyl-leucyl-phenylalanine. The role of protein kinase C.
Topics: Calcimycin; Calcium; Cell Membrane; Chloride Channels; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peptide Fragments; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Neutrophil-specific antigen NB1 inhibits neutrophil-endothelial cell interactions.
Topics: Antibodies; Cell Adhesion; Chemotaxis, Leukocyte; Complement C5a; Endothelium, Vascular; GPI-Linked Proteins; Humans; Immunoglobulin Fab Fragments; Isoantigens; Kinetics; Luminescent Measurements; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Activated neutrophils from rat injured isolated hepatocytes.
Topics: Alanine Transaminase; Animals; Catalase; Cells, Cultured; Culture Media, Conditioned; Deferoxamine; Liver; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Influence of dichloromethylene diphosphonate on reactive oxygen species production by human neutrophils.
Topics: Bone Resorption; Calcimycin; Clodronic Acid; Dose-Response Relationship, Drug; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Xanthine Oxidase; Xanthines | 1993 |
Phospholipase C and phospholipase D are activated independently of each other in chemotactic peptide-stimulated human neutrophils.
Topics: Cytochalasin B; Enzyme Activation; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phospholipase D; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Neutrophil-mediated proteolysis. Differential roles for cathepsin G and elastase.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antibodies, Monoclonal; Cathepsin G; Cathepsins; Cephalosporins; Fibronectins; Humans; Leukocyte Elastase; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Pyrrolidines; Serine Endopeptidases; Serpins; Tetradecanoylphorbol Acetate | 1993 |
Calcium-dependent protein kinase C activity of neutrophils in localized juvenile periodontitis.
Topics: Aggressive Periodontitis; Biological Transport; Calcium; Chemotaxis, Leukocyte; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
CD53, a protein with four membrane-spanning domains, mediates signal transduction in human monocytes and B cells.
Topics: Adenosine Diphosphate Ribose; Alkaloids; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; B-Lymphocytes; Calcium; Cell Line; Humans; Mice; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Respiratory Burst; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tetraspanin 25 | 1993 |
Ascorbic acid recycling in human neutrophils.
Topics: Adult; Antioxidants; Ascorbic Acid; Catalase; Cells, Cultured; Dehydroascorbic Acid; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Sodium Fluoride; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines | 1993 |
Extracellular production of singlet oxygen by stimulated macrophages quantified using 9,10-diphenylanthracene and perylene in a polystyrene film.
Topics: Animals; Anthracenes; Cell Adhesion; Free Radicals; Hydrogen Peroxide; Macrophage Activation; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Perylene; Polystyrenes; Rats; Rats, Sprague-Dawley; Sodium Hypochlorite; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1993 |
Activation of neutrophils NADPH oxidase by PMA: cytosol activity is translocated in phorbol-primed neutrophils.
Topics: Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Tetradecanoylphorbol Acetate | 1993 |
Sphingosine mobilizes intracellular calcium in human neutrophils.
Topics: Biological Transport; Calcium; Cell Compartmentation; Cell Death; Dose-Response Relationship, Drug; Edetic Acid; Fluorescent Dyes; Fura-2; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylcholine; Saponins; Sphingosine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C.
Topics: Amino Acid Sequence; Biological Transport; Cell Membrane; Cell-Free System; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Molecular Sequence Data; Myristates; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Oligopeptides; Phosphoproteins; Phosphorylation; Protein Kinase C; Sodium Dodecyl Sulfate; Tetradecanoylphorbol Acetate | 1993 |
Calcium-binding myeloid protein (P8,14) is phosphorylated in fMet-Leu-Phe-stimulated neutrophils.
Topics: Calcimycin; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Calmodulin; Cell Adhesion Molecules, Neuronal; Humans; In Vitro Techniques; Leukocyte L1 Antigen Complex; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Precipitin Tests; Tetradecanoylphorbol Acetate; Trifluoperazine | 1993 |
Production of hydrogen peroxide by neutrophilic polymorphonuclear leukocytes in patients with diabetic nephropathy.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hydrogen Peroxide; Immunoglobulin G; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1993 |
Enhancement of pertussis-toxin-sensitive Na(+)-dependent uridine transporter activity in HL-60 granulocytes by N-formylmethionyl-leucyl-phenylalanine.
Topics: Amino Acid Sequence; Biological Transport; Calcimycin; Calcium; Extracellular Space; Granulocytes; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Sodium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine; Virulence Factors, Bordetella | 1993 |
Superoxide anion production and phospholipase D-mediated generation of diacylglycerol are subnormal after N-formyl-methionyl-leucyl-phenylalanine stimulation of polymorphonuclear granulocytes in polycythemia vera.
Topics: Adult; Age Factors; Aged; Calcium; Diglycerides; Glycerophospholipids; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Luminescent Measurements; Membrane Potentials; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Polycythemia Vera; Receptors, Formyl Peptide; Receptors, Immunologic; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
Adenosine inhibits fMLP-stimulated adherence and superoxide anion generation by human neutrophils at an early step in signal transduction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcimycin; Cell Adhesion; Cell Membrane; Complement C5a; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Signal Transduction; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Neutrophils stimulated with a chemotactic peptide or a phorbol ester exhibit different alterations in the activities of a battery of protein kinases.
Topics: Animals; Ethers, Cyclic; Guinea Pigs; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Substrate Specificity; Tetradecanoylphorbol Acetate | 1993 |
The chemotactic factor N-formylmethionyl-leucyl-phenylalanine activates microtubule-associated protein 2 (MAP) kinase and a MAP kinase kinase in polymorphonuclear leucocytes.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphorylation; Protein Kinases; Rabbits; Substrate Specificity; Tetradecanoylphorbol Acetate | 1993 |
Changes in mechanisms of monocyte/macrophage-mediated cytotoxicity during culture. Reactive oxygen intermediates are involved in monocyte-mediated cytotoxicity, whereas reactive nitrogen intermediates are employed by macrophages in tumor cell killing.
Topics: Arginine; Cells, Cultured; Cytotoxicity, Immunologic; DNA, Neoplasm; Humans; Leukemia, Erythroblastic, Acute; Luminescent Measurements; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Improvement of superoxide production in monocytes from patients with chronic granulomatous disease by recombinant cytokines.
Topics: Cells, Cultured; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Granulomatous Disease, Chronic; Humans; Interferon-gamma; Interleukin-1; Interleukin-3; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Enhancement of wound healing by the alkaloid taspine defining mechanism of action.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cell Line; Chemotaxis; Chemotaxis, Leukocyte; DNA Replication; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Inflammation; Lung; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Thymidine; Wound Healing; Wounds and Injuries | 1993 |
Stimulating effects of mercuric- and silver ions on the superoxide anion production in human polymorphonuclear leukocytes.
Topics: Anions; Humans; Kinetics; Mercury; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Respiratory Burst; Silver; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Lidocaine inhibits priming and protein tyrosine phosphorylation of human peripheral neutrophils.
Topics: Humans; Lidocaine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Myeloperoxidase-dependent loss of malondialdehyde: a limitation for detecting neutrophil-mediated lipid peroxidation.
Topics: Chlorides; Humans; Hydrogen Peroxide; Hypochlorous Acid; Lipid Peroxidation; Liposomes; Malondialdehyde; Models, Chemical; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1993 |
Regulation of neutrophil respiratory burst by protein phosphatases.
Topics: Ethers, Cyclic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
The phosphatase inhibitor 2,3-diphosphoglycerate interferes with phospholipase D activation in rabbit peritoneal neutrophils.
Topics: 2,3-Diphosphoglycerate; Acetylglucosaminidase; Animals; Diphosphoglyceric Acids; Dose-Response Relationship, Drug; Enzyme Activation; Glycerophospholipids; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrophenols; Organophosphorus Compounds; Phosphatidic Acids; Phospholipase D; Rabbits; Streptomyces; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
A new sensitive chemiluminescence probe, L-012, for measuring the production of superoxide anion by cells.
Topics: Complement C5a; Humans; Imidazoles; Indicators and Reagents; Interferon-gamma; Kinetics; Leukemia, Eosinophilic, Acute; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyrazines; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Albumin inhibits neutrophil spreading and hydrogen peroxide release by blocking the shedding of CD43 (sialophorin, leukosialin).
Topics: Antigens, CD; Cell Adhesion; Cell Movement; Chromatography, Affinity; Complement C5a; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Kinetics; Leukosialin; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophils; Pancreatic Elastase; Periodic Acid; Recombinant Proteins; Serum Albumin; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Mechanism and regulation of neutrophil priming by platelet-activating factor.
Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Human neutrophil adhesion to bovine aortic endothelium. Evidence for endothelial lipoxygenase activity.
Topics: Animals; Arachidonic Acid; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Inflammation; Leukotriene B4; Lipoxygenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved sel
Topics: Alkaloids; Bucladesine; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipase D; Protein Kinase C; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Deficient glucose phosphorylation as a possible common denominator and its relation to abnormal leucocyte function, in glycogen storage disease 1b patients.
Topics: 3-O-Methylglucose; Calcium; Deoxyglucose; Glucose; Glycogen Storage Disease Type I; Humans; Methylglucosides; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutropenia; Neutrophils; Phosphorylation; Phosphotransferases; Respiratory Burst; Tetradecanoylphorbol Acetate | 1993 |
Changes in free intracellular calcium and production of reactive oxygen metabolites in human leukocytes by soluble and particulate stimuli.
Topics: Asbestos; Asbestos, Serpentine; Calcium; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quartz; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1993 |
Luminol chemiluminescence in rat macrophages and granulocytes: the role of NO, O2-/H2O2, and HOCl.
Topics: Animals; Arginine; Azides; Calcimycin; Catalase; Granulocytes; Hydrogen Peroxide; Hypochlorous Acid; Kupffer Cells; Luminescent Measurements; Luminol; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Rats; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Avidin attachment to biotinylated human neutrophils induces generation of superoxide anion.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Avidin; Biotin; Electron Spin Resonance Spectroscopy; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Characterization of a 64-kd protein phosphorylated during chemotactic activation with IL-8 and fMLP of human polymorphonuclear leukocytes. I. Phosphorylation of a 64-kd protein and other proteins.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Blood Proteins; Chemotactic Factors; Complement C5a; Humans; Interleukin-8; Kinetics; Leukotriene B4; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1993 |
Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils.
Topics: Calcium; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-1; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Effect of peritoneal dialysis effluent on superoxide anion production by polymorphonuclear neutrophils.
Topics: Candida; Hemodialysis Solutions; Humans; In Vitro Techniques; Kidney Failure, Chronic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Dialysis, Continuous Ambulatory; Staphylococcus epidermidis; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Lucigenin-dependent chemiluminescence in articular chondrocytes.
Topics: Acridines; Animals; Antioxidants; Cartilage, Articular; Cell Adhesion; Concanavalin A; Cytochrome c Group; Female; Free Radicals; Hydrogen Peroxide; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Rabbits; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Relationship between respiratory burst and adhesiveness capacity in elderly polymorphonuclear cells.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antibodies, Monoclonal; Cell Adhesion; Female; Humans; In Vitro Techniques; Integrins; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Phorbol myristate acetate induction of chemotactic migration of human polymorphonuclear neutrophils.
Topics: Chemotaxis, Leukocyte; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Tetradecanoylphorbol Acetate | 1993 |
Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.
Topics: Biological Transport; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Tetradecanoylphorbol Acetate | 1993 |
Leukocyte-deactivating factor from macrophages: partial purification and biochemical characterization. A novel cytokine.
Topics: Animals; Chromatography, High Pressure Liquid; Cytokines; Macrophages; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Peptides; Retinaldehyde; Stereoisomerism; Tetradecanoylphorbol Acetate | 1993 |
Extracellular acidic pH modulates oxygen-dependent cytotoxic responses mediated by polymorphonuclear leucocytes and monocytes.
Topics: Antigen-Antibody Complex; Cells, Cultured; Cytotoxicity, Immunologic; Humans; Hydrogen-Ion Concentration; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1993 |
Direct and indirect effects of E. coli lipopolysaccharide on isolated human polymorphonuclear granulocytes and mixed leukocytes.
Topics: Cell Aggregation; Culture Media; Endotoxins; Escherichia coli; Humans; Leukocytes; Luminescent Measurements; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Respiratory Burst; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Involvement of calcium in modulation of neutrophil function by phorbol esters that activate protein kinase C isotypes and related enzymes.
Topics: Calcium; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Free Radicals; Humans; Imidazoles; Ionomycin; Isoenzymes; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phorbol Esters; Platelet Aggregation Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Novel antibodies specific for proteolyzed forms of protein kinase C: production of anti-peptide antibodies available for in situ analysis of intracellular limited proteolysis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Formation; Calcimycin; Calpain; Cell Line; Immunoblotting; Immunohistochemistry; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1993 |
Haemopoietic stem cell development to neutrophils is associated with subcellular redistribution and differential expression of protein kinase C subspecies.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cytosol; DNA Replication; Enzyme Activation; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Interleukin-3; Isoenzymes; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Tetradecanoylphorbol Acetate | 1993 |
Agonist-dependent phosphorylation of N-formylpeptide and activation peptide from the fifth component of C (C5a) chemoattractant receptors in differentiated HL60 cells.
Topics: Amino Acid Sequence; beta-Adrenergic Receptor Kinases; Complement C5a; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Receptor, Anaphylatoxin C5a; Receptors, Complement; Receptors, Formyl Peptide; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Use of Laurdan fluorescence in studying plasma membrane organization of polymorphonuclear leukocytes during the respiratory burst.
Topics: 2-Naphthylamine; Cell Membrane; Fluorescent Dyes; Humans; Laurates; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1993 |
Transmembrane signaling pathways involved in phagocytosis and associated activation of NADPH oxidase mediated by Fc gamma Rs in human neutrophils.
Topics: Arachidonic Acid; Calcium; Enzyme Activation; Erythrocytes; Humans; Immunoglobulin G; In Vitro Techniques; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phagocytosis; Phospholipids; Receptors, IgG; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
A rapid whole blood lysis technique for the diagnosis of moderate or severe leukocyte adhesion deficiency (LAD).
Topics: Adult; Antigens, CD; Female; Flow Cytometry; Granulocytes; Hemolysis; Humans; Immunologic Deficiency Syndromes; Integrins; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Effect of mode of activation of human eosinophils on tracheal smooth muscle contraction in guinea pigs.
Topics: Acetamides; Acetylcholine; Animals; Cytochalasin B; Eosinophils; Erythropoietin; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; N-Formylmethionine Leucyl-Phenylalanine; Phenyl Ethers; Tetradecanoylphorbol Acetate; Trachea | 1993 |
Flow cytometric analysis of cell function: cytosolic Ca++ modulation in human polymorphonuclear leukocytes and T lymphocytes.
Topics: Aniline Compounds; Calcium; Cytochalasin B; Flow Cytometry; Fluorescent Dyes; Humans; In Vitro Techniques; Light; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Scattering, Radiation; T-Lymphocytes; Tetradecanoylphorbol Acetate; Xanthenes | 1994 |
A synthetic peptide containing a predominant protein kinase C site within p47phox inhibits the NADPH oxidase in intact neutrophils.
Topics: Amino Acid Sequence; Binding Sites; Binding, Competitive; Cytochalasin B; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Kinase C; Respiratory Burst; Tetradecanoylphorbol Acetate | 1996 |
Interactions of cis-fatty acids and their anilides with formyl-methionyl-leucyl-phenylalanine, phorbol myristate acetate and dioctanoyl-s,n-glycerol in human leukocytes.
Topics: Analysis of Variance; Anilides; Calcium; Diglycerides; Fatty Acids, Monounsaturated; Humans; Linoleic Acid; Linoleic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Oleic Acids; Plant Oils; Rapeseed Oil; Reactive Oxygen Species; Respiratory Burst; Stereoisomerism; Tetradecanoylphorbol Acetate | 1995 |
Involvement of vicinal dithiols in differential regulation of fMLP and phorbol ester-activated phospholipase D in stimulated human neutrophils.
Topics: Arsenicals; Calcium; Cells, Cultured; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Role of Rho in chemoattractant-activated leukocyte adhesion through integrins.
Topics: Amino Acid Sequence; Animals; Antigens, CD; B-Lymphocytes; Cell Adhesion; Cells, Cultured; Chemotactic Factors; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Integrin alpha4beta1; Integrins; Interleukin-8; Mice; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Interleukin; Receptors, Interleukin-8A; Receptors, Lymphocyte Homing; Receptors, Peptide; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Vascular Cell Adhesion Molecule-1 | 1996 |
Biological characteristics of chronic eosinophilic leukemia cells with a t(2;5)(p23;q35) translocation.
Topics: Adult; Antigens, Neoplasm; Antigens, Surface; Chemotactic Factors; Chemotaxis, Leukocyte; Chromosomes, Human, Pair 2; Chromosomes, Human, Pair 5; Combined Modality Therapy; Complement C5a; Eosinophils; Folliculitis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Interleukins; Leukotriene C4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Neoplastic Stem Cells; Oxygen; Tetradecanoylphorbol Acetate; Translocation, Genetic; Tumor Stem Cell Assay | 1995 |
A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells.
Topics: Animals; Blood Donors; Calcimycin; Cell Membrane; Enzyme Activation; Humans; Hydrolysis; Leukocytes; Linear Models; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipase D; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Standardization of a flow cytometric assay for phagocyte respiratory burst activity.
Topics: Adult; Citrates; Citric Acid; Edetic Acid; Flow Cytometry; Heparin; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Phagocytes; Reproducibility of Results; Respiratory Burst; Tetradecanoylphorbol Acetate; Yersinia enterocolitica | 1996 |
Production of reactive oxygen metabolites by opsonized fungi and bacteria isolated from indoor air, and their interactions with soluble stimuli, fMLP or PMA.
Topics: Adult; Air Microbiology; Air Pollution, Indoor; Analysis of Variance; Aspergillus; Calcium; Candida; Carcinogens; Cladosporium; Fungi; Fura-2; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Paecilomyces; Penicillium; Reactive Oxygen Species; Stachybotrys; Streptomyces; Tetradecanoylphorbol Acetate | 1995 |
Activation of human monocyte functions by tumor necrosis factor: rapid priming for enhanced release of superoxide and erythrophagocytosis, but no direct triggering of superoxide release.
Topics: Adult; Complement C3b; Concanavalin A; Cytoplasm; Erythrocytes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Phosphotyrosine; Receptors, Leukocyte-Adhesion; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1996 |
Bradykinin stimulates phosphoinositide turnover and phospholipase C but not phospholipase D and NADPH oxidase in human neutrophils.
Topics: Amino Acid Sequence; Bradykinin; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nitric Oxide; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils.
Topics: alpha-Defensins; Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Blood Proteins; Carrier Proteins; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Defensins; Humans; Interleukin-8; Ionomycin; Mice; Mice, Inbred BALB C; Mice, SCID; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of the human neutrophil respiratory burst by native and synthetic surfactant.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Amino Acid Sequence; Animals; Humans; In Vitro Techniques; Kinetics; Lactoferrin; Liposomes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphatidic Acids; Phosphatidylglycerols; Protein Kinase C; Pulmonary Surfactants; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Superoxides; Swine; Tetradecanoylphorbol Acetate | 1996 |
Role of cytokines, tyrosine kinase, and protein kinase C on production of superoxide and induction of scavenging enzymes in human leukocytes.
Topics: Adult; Bleomycin; Calcimycin; Catalase; Cytokines; Enzyme Induction; Female; Glutathione Peroxidase; Humans; Interferon-gamma; Interleukin-1; Lymphocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
The nucleoside diphosphate kinase of human neutrophils.
Topics: Cell Membrane; Cytochalasin B; Cytosol; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Isoenzymes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleoside-Diphosphate Kinase; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Translocation of p190rho guanosine triphosphatase-activating protein from cytosol to the membrane in human neutrophils stimulated with different agonists.
Topics: Cell Membrane; Concanavalin A; Cytosol; Enzyme Activation; Guanine Nucleotide Exchange Factors; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Nuclear Proteins; Oxygen Consumption; Phosphoproteins; Repressor Proteins; Tetradecanoylphorbol Acetate | 1996 |
Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation.
Topics: Amino Acid Sequence; Binding, Competitive; Cell Differentiation; Chemotactic Factors; Enzyme Activation; Enzyme Inhibitors; Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Involvement of protein phosphatase 2A in PKC-independent pathway of neutrophil superoxide generation by fMLP.
Topics: Calcium; Enzyme Inhibitors; Ethers, Cyclic; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Phosphatase 1; Protein Phosphatase 2; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Okadaic acid inhibits the signal responsible for activation of the NADPH-oxidase in neutrophils stimulated with serum-opsonized yeast.
Topics: Animals; Cell Fusion; Enzyme Inhibitors; Ethers, Cyclic; Humans; Hydrogen Peroxide; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Okadaic Acid; Phagocytosis; Phosphoprotein Phosphatases; Rabbits; Reactive Oxygen Species; Respiratory Burst; Saccharomyces cerevisiae; Tetradecanoylphorbol Acetate | 1996 |
Formyl-methionyl-leucyl-phenylalanine and a calcium ionophore A23187 reverse the inhibition of phorbol myristate acetate-induced oxidative burst by linoleic and oleic acid anilides.
Topics: Anilides; Calcimycin; Calcium; Carcinogens; Drug Synergism; Humans; Ionophores; Linoleic Acids; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acids; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1996 |
Topographic distribution of CD18 integrin on human neutrophils as related to shape changes and movement induced by chemotactic peptide and phorbol esters.
Topics: CD18 Antigens; Cell Movement; Cell Size; Humans; Immunohistochemistry; Integrins; Microscopy, Immunoelectron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1996 |
FcgammaRII-mediated adhesion and phagocytosis induce L-plastin phosphorylation in human neutrophils.
Topics: Actinin; Antibodies, Monoclonal; Antigens, CD; Calcium; CD18 Antigens; Cell Adhesion; Cell Membrane; Cells, Cultured; Egtazic Acid; Humans; Immunoglobulin Fab Fragments; Kinetics; Leukocyte-Adhesion Deficiency Syndrome; Membrane Glycoproteins; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Phosphoproteins; Phosphorylation; Receptors, IgG; Tetradecanoylphorbol Acetate; Vinculin | 1996 |
Activation of proton pumping in human neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases.
Topics: Enzyme Activation; Exocytosis; Gelatinases; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proton-Translocating ATPases; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Vacuoles | 1996 |
Nitric oxide is not involved in hepatocyte killing by neutrophils activated by N-formyl-methionyl-leucylphenylalanine or phorbol myristate acetate in vitro.
Topics: Animals; Cells, Cultured; Coculture Techniques; Liver; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nitric Oxide; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Investigation of the role of protein kinase C and tyrosine kinases during the rapid and sustained release of superoxide from adherent human neutrophils.
Topics: Cell Adhesion; Cinnamates; Enzyme Inhibitors; Humans; Indoles; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophils; Phenols; Protein Kinase C; Protein-Tyrosine Kinases; Sulfides; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
A CD66a-specific, activation-dependent epitope detected by recombinant human single chain fragments (scFvs) on CHO transfectants and activated granulocytes.
Topics: Animals; Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; CHO Cells; Cricetinae; Epitopes; HeLa Cells; HL-60 Cells; Humans; Immunoglobulin Fragments; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Tumor necrosis factor-alpha and FMLP receptors are functionally linked during FMLP-stimulated activation of adherent human neutrophils.
Topics: Animals; Antigens, CD; Chemotactic Factors; Cycloheximide; Dactinomycin; Humans; Hydrogen Peroxide; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Synthesis Inhibitors; Rabbits; Rats; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Rat eosinophils: isolation and characterization of superoxide production.
Topics: Animals; Calcimycin; Cell Separation; Cytochalasin B; Eosinophils; Humans; In Vitro Techniques; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Modulation of neutrophil migration by exogenous gaseous nitric oxide.
Topics: Aminoquinolines; Animals; Calcium; Chemotaxis, Leukocyte; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Egtazic Acid; Enzyme Inhibitors; Female; Guanylate Cyclase; In Vitro Techniques; Kinetics; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Tetradecanoylphorbol Acetate | 1996 |
Flow cytometric investigation of neutrophil activation pathways by n-formyl-Met-Leu-Phe and phorbol myristate acetate.
Topics: Alkaloids; Antigens, CD; Calcium; Edetic Acid; Enzyme Inhibitors; Flow Cytometry; Humans; In Vitro Techniques; Ionophores; Light; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Scattering, Radiation; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Horse spleen ferritin inhibits superoxide production by equine blood monocytes in vitro.
Topics: Animals; Catalase; Cells, Cultured; Deferoxamine; Ferritins; Horses; Iron-Dextran Complex; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Changes of fatty acid composition and oxidative metabolism of human neutrophils migrating into an inflammatory exudate.
Topics: Chemotaxis, Leukocyte; Exudates and Transudates; Fatty Acids; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Respiratory Burst; Skin Window Technique; Tetradecanoylphorbol Acetate | 1996 |
The direct effect of interferon-gamma on human eosinophilic leukemia cell lines: the induction of interleukin-5 mRNA and the presence of an interferon-gamma receptor.
Topics: Antigens, CD; Base Sequence; Eosinophils; Gene Expression Regulation, Leukemic; Humans; Imidazoles; Interferon gamma Receptor; Interferon-gamma; Interleukin-5; Leukemia, Eosinophilic, Acute; Luminescent Measurements; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Proteins; Neoplastic Stem Cells; Pyrazines; Receptors, Interferon; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Isoluminol-enhanced chemiluminescence: a sensitive method to study the release of superoxide anion from human neutrophils.
Topics: Catalase; Cytochrome c Group; Free Radical Scavengers; Humans; Hydrogen Peroxide; Kinetics; Light; Luminescent Measurements; Luminol; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Sensitivity and Specificity; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Contact-induced modulation of neutrophil elastase secretion and phagocytic activity by platelets.
Topics: Blood Platelets; Calcimycin; Humans; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activation; Platelet Adhesiveness; Tetradecanoylphorbol Acetate | 1996 |
Chemiluminescence response of cervine neutrophils to various stimuli.
Topics: Animals; Cattle; Concanavalin A; Deer; Female; Humans; In Vitro Techniques; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Orchiectomy; Species Specificity; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Basophils; Binding, Competitive; Bryostatins; Chemokine CCL2; Chemokine CCL5; Complement C5a; Cyclosporine; Histamine Release; Humans; Interleukin-1; Interleukin-8; Kinetics; Lactones; Leukotriene C4; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Platelet Activating Factor; Protein Binding; Tetradecanoylphorbol Acetate | 1996 |
Sulfatide-induced L-selectin activation generates intracellular oxygen radicals in human neutrophils: modulation by extracellular adenosine.
Topics: Adenosine; Calcium; Enzyme Activation; Free Radicals; Humans; Ionomycin; L-Selectin; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotyrosine; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Sulfoglycosphingolipids; Tetradecanoylphorbol Acetate | 1996 |
Dephosphorylation of a 34kd triton-insoluble F-actin pool protein is associated with phorbol ester-induced actin polymerization in human polymorphonuclear leukocytes.
Topics: Actins; Biopolymers; Detergents; Enzyme Inhibitors; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Octoxynol; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Solubility; Tetradecanoylphorbol Acetate | 1996 |
Production of hydrogen peroxide by alveolar macrophages. Effect of barbiturates.
Topics: Animals; Barbiturates; Horseradish Peroxidase; Hydrogen Peroxide; Hypnotics and Sedatives; In Vitro Techniques; Luminescent Measurements; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thiopental | 1995 |
The neuropeptide alpha-MSH has specific receptors on neutrophils and reduces chemotaxis in vitro.
Topics: alpha-MSH; Analysis of Variance; Chemotaxis, Leukocyte; Cyclic AMP; DNA Primers; Humans; Interleukin-8; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrites; Polymerase Chain Reaction; Receptors, Corticotropin; Receptors, Melanocortin; Receptors, Pituitary Hormone; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Dephosphorylation of cofilin in polymorphonuclear leukocytes derived from peripheral blood.
Topics: Actin Depolymerizing Factors; Androstadienes; Animals; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethers, Cyclic; Humans; Ionophores; Marine Toxins; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Swine; Tetradecanoylphorbol Acetate; Wortmannin | 1996 |
Modulation by protein kinase C of the enhanced responsiveness to tachykinins in ovalbumin-sensitized guinea pig alveolar macrophages.
Topics: Animals; Bordetella pertussis; Cytochrome c Group; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Guinea Pigs; Immunization; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Ovalbumin; Peptide Fragments; Protein Kinase C; Receptors, Tachykinin; Staurosporine; Substance P; Superoxides; Tachykinins; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of chemiluminescence response of human polymorphonuclear leukocytes by three different stimulations in hyperosmotic condition comparable to the renal medulla.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indicators and Reagents; Kidney Medulla; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Sodium Chloride; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Urea; Zymosan | 1996 |
Phospholipase A2 is involved in the mechanism of activation of neutrophils by polychlorinated biphenyls.
Topics: Animals; Arachidonic Acid; Aroclors; Aspirin; Cyclooxygenase Inhibitors; Hydroxyurea; In Vitro Techniques; Lipoxygenase Inhibitors; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phospholipases A; Phospholipases A2; Polychlorinated Biphenyls; Quinacrine; Rats; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1996 |
Comparison of chemotaxis and superoxide generation of indium-111-oxine- and technetium-99m-HMPAO-labelled granulocytes.
Topics: Chemotaxis, Leukocyte; Granulocytes; N-Formylmethionine Leucyl-Phenylalanine; Organometallic Compounds; Organotechnetium Compounds; Oximes; Oxyquinoline; Superoxides; Technetium Tc 99m Exametazime; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase A downregulates the phosphorylation of p47 phox in human neutrophils: a possible pathway for inhibition of the respiratory burst.
Topics: Bucladesine; Carbazoles; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Inhibitors; Humans; Indoles; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphoproteins; Phosphorylation; Pyrroles; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Cord blood neutrophil responses to polyunsaturated fatty acids: effects on degranulation and oxidative respiratory burst.
Topics: Adult; Arachidonic Acid; Cytoplasmic Granules; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Fetal Blood; Humans; Infant, Newborn; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate | 1996 |
Comparison of tBuBHQ with chemotactic peptide and phorbol ester in O2- production in HL-60 cells.
Topics: Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Inhibitors; HL-60 Cells; Humans; Hydroquinones; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Granulocytes harvested following G-CSF-enhanced leukocyte recovery retain their functional capacity during in vitro culture for 72 hours.
Topics: Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Blood Preservation; Blood Transfusion, Autologous; Cell Adhesion; Cell Survival; Cells, Cultured; Cryopreservation; Filgrastim; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematologic Neoplasms; Humans; Immunophenotyping; Leukapheresis; Leukocyte Transfusion; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phagocytosis; Receptors, Immunologic; Recombinant Proteins; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Phosphorylation of myeloid-related proteins MRP-14 and MRP-8 during human neutrophil activation.
Topics: Antigens, Differentiation; Arachidonic Acid; Calcimycin; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cell Membrane; Cytochalasin B; Cytoplasm; Electrophoresis, Gel, Two-Dimensional; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Activation of p38 in stimulated human neutrophils: phosphorylation of the oxidase component p47phox by p38 and ERK but not by JNK.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Dehydrogenase; NADPH Oxidases; Nerve Tissue Proteins; Neutrophils; Peptide Fragments; Peptide Mapping; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein Kinases; Receptor Protein-Tyrosine Kinases; Receptor, EphA8; Tetradecanoylphorbol Acetate | 1996 |
Evaluation of the effects of defensins on neutrophil functions.
Topics: Animals; Blood Proteins; Cell Adhesion; Defensins; Guinea Pigs; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
Topics: Amino Acid Sequence; Calcium; Chemotactic Factors; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Superoxide release and NADPH oxidase components in mature human phagocytes: correlation between functional capacity and amount of functional proteins.
Topics: Adult; Bronchoalveolar Lavage Fluid; Eosinophilia; Eosinophils; Humans; In Vitro Techniques; Kinetics; Lung Neoplasms; Macrophages, Alveolar; Membrane Glycoproteins; Membrane Transport Proteins; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Dehydrogenase; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phagocytes; Phosphoproteins; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Activation of Mac-1 (CD11b/CD18)-bound factor X by released cathepsin G defines an alternative pathway of leucocyte initiation of coagulation.
Topics: Blood Coagulation; Cathepsin G; Cathepsins; Cell Fractionation; Cell Line; Cell Membrane; Cytoplasmic Granules; Endopeptidases; Factor X; Factor Xa; Humans; Kinetics; Leukocytes; Macrophage-1 Antigen; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Tyrosine phosphorylation and subcellular redistribution of p125 ras guanosine triphosphatase-activating protein in human neutrophils stimulated with FMLP.
Topics: Cell Membrane; Concanavalin A; Cytosol; GTPase-Activating Proteins; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Phosphotyrosine; Proteins; ras GTPase-Activating Proteins; Respiratory Burst; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine | 1996 |
Vesicular transport of histamine in stimulated human basophils.
Topics: Basophils; Biological Transport; Cytoplasmic Granules; Exocytosis; Histamine; Histamine Release; Humans; Membrane Fusion; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Organelles; Tetradecanoylphorbol Acetate | 1996 |
Platelet/polymorphonuclear leukocyte interaction in dynamic conditions: evidence of adhesion cascade and cross talk between P-selectin and the beta 2 integrin CD11b/CD18.
Topics: Antibodies, Monoclonal; Blood Platelets; Calcium; CD18 Antigens; Cell Adhesion; Enzyme Inhibitors; Humans; Macromolecular Substances; Macrophage-1 Antigen; Magnesium; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; P-Selectin; Platelet Activation; Protein Conformation; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox.
Topics: Adult; Burns; Cell-Free System; Cytochrome b Group; Cytosol; Disease Susceptibility; Female; Humans; Immunocompromised Host; Infections; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxygen; Phosphoproteins; Platelet Activating Factor; Respiratory Burst; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Mechanisms of NADPH oxidase activation in human neutrophils: p67phox is required for the translocation of rac 1 but not of rac 2 from cytosol to the membranes.
Topics: Blotting, Western; Cell Membrane; Concanavalin A; Cytoplasm; Granulomatous Disease, Chronic; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; rac GTP-Binding Proteins; Tetradecanoylphorbol Acetate | 1995 |
Priming of neutrophil and monocyte activation in human immunodeficiency virus infection. Comparison of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor and interferon-gamma.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; CD4 Lymphocyte Count; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; Humans; Interferon-gamma; Luminescent Measurements; Male; Matched-Pair Analysis; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Zidovudine | 1996 |
Polymorphonuclear leucocyte (PMN)-derived inflammatory cytokines--regulation by oxygen tension and extracellular matrix.
Topics: Culture Media; Culture Techniques; Cytokines; Extracellular Matrix Proteins; Humans; Interleukin-1; Interleukin-8; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Partial Pressure; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Neutrophil migration, oxidative metabolism, and adhesion in elderly and young subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cell Adhesion; Chemotaxis, Leukocyte; Female; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Topics: Adult; Anti-Asthmatic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Azithromycin; Calcimycin; Cell Membrane; Clarithromycin; Erythromycin; Humans; Ionophores; Luminescent Measurements; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Roxithromycin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Regulation of neutrophil superoxide generation by alpha-tocopherol in human peripheral and umbilical-cord blood.
Topics: Annexin A1; Calcimycin; Fetal Blood; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Vitamin E | 1996 |
Hck is activated by opsonized zymosan and A23187 in distinct subcellular fractions of human granulocytes.
Topics: Calcimycin; Calcium; Cell Compartmentation; Cell Degranulation; Cell Differentiation; Cells, Cultured; Cytoplasmic Granules; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Opsonin Proteins; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tretinoin; Zymosan | 1997 |
Exocytosis of arginine-specific ADP-ribosyltransferase and p33 induced by A23187 and calcium or serum-opsonized zymosan in chicken polymorphonuclear leukocytes.
Topics: Acetyltransferases; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Calcimycin; Calcium; Chickens; Dimethyl Sulfoxide; Exocytosis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proteins; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Field trial of a diluent for the transportation of human semen at ambient temperatures.
Topics: Acrosome; Buffers; Calcimycin; Cell Survival; Citric Acid; Egg Yolk; Humans; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Preservation, Biological; Reactive Oxygen Species; Semen; Sperm Motility; Spermatozoa; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Transportation | 1997 |
Pentoxifylline inhibits tumor necrosis factor alpha-induced priming of human neutrophils.
Topics: Dose-Response Relationship, Drug; Humans; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Pentoxifylline; Phosphodiesterase Inhibitors; Recombinant Proteins; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
In vitro interaction between dirithromycin or its metabolite, erythromycylamine, and oxidative polymorphonuclear metabolism.
Topics: Anti-Bacterial Agents; Erythromycin; Humans; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Alterations in stimulus-induced integrin expression in peripheral blood neutrophils of patients with diabetic retinopathy.
Topics: Adult; Aged; Aged, 80 and over; CD18 Antigens; Diabetic Retinopathy; Female; Humans; Integrins; L-Selectin; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1997 |
Effects of 3-phenylamino-1,2-propanediol and its mono- and dioleylesters on the production of reactive oxygen metabolites in human polymorphonuclear leukocytes.
Topics: Analysis of Variance; Cell Separation; Cell Survival; Dose-Response Relationship, Drug; Esters; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Propylene Glycols; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1997 |
Palmitic acid anilide-induced respiratory burst in human polymorphonuclear leukocytes is inhibited by a protein kinase C inhibitor, Ro 31-8220.
Topics: Adult; Anilides; Calcium; Enzyme Inhibitors; Humans; Indoles; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Palmitic Acids; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of cytosolic phospholipase A2 by annexin V in differentiated permeabilized HL-60 cells. Evidence of crucial importance of domain I type II Ca2+-binding site in the mechanism of inhibition.
Topics: Annexin A5; Arachidonic Acid; Bacterial Proteins; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Membrane Permeability; Cytosol; Enzyme Inhibitors; Female; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Indoles; Kinetics; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Placenta; Pregnancy; Protein Kinase C; Recombinant Proteins; Streptolysins; Tetradecanoylphorbol Acetate | 1997 |
Preventive effect of rebamipide on gastric mucosal cell damage evoked by activation of formyl-methionyl-leucyl-phenylalanine receptors of rabbit neutrophils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Gastric Mucosa; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolones; Rabbits; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
A sensitive flow cytometric method for measuring the oxidative burst.
Topics: Flow Cytometry; Fluorescent Dyes; Humans; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
An in-frame triplet deletion within the gp91-phox gene in an adult X-linked chronic granulomatous disease patient with residual NADPH-oxidase activity.
Topics: Adult; Amino Acid Sequence; Antibodies; Bacterial Infections; Cytochrome b Group; Exons; Fatal Outcome; Female; Genetic Carrier Screening; Granulocytes; Granulomatous Disease, Chronic; Heme; Humans; Male; Membrane Glycoproteins; Models, Structural; Molecular Sequence Data; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Pedigree; Peptide Fragments; Polymorphism, Genetic; Protein Conformation; Sequence Deletion; Superoxides; Tetradecanoylphorbol Acetate; X Chromosome; Zymosan | 1997 |
Activation of the NF-kappaB pathway by inflammatory stimuli in human neutrophils.
Topics: Base Sequence; Binding Sites; Cell Nucleus; Cells, Cultured; Cytokines; Dimerization; DNA-Binding Proteins; HIV; Humans; I-kappa B Proteins; Inflammation; Interferons; Interleukins; Leukotriene B4; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1997 |
Phosphatidylinositol-3-kinase pathway is stimulated by fungal lipid containing cocoa butter equivalents (CBE) in FMet-Leu-Phe (FMLP)- and phorbolester (PMA)-challenged human neutrophils.
Topics: Cacao; Enzyme Inhibitors; Fungi; Humans; In Vitro Techniques; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Respiratory Burst; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Nitric oxide-releasing particles inhibit phagocytosis in human neutrophils.
Topics: Actins; Cell Adhesion; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Phagocytosis; Saccharomyces cerevisiae; Tetradecanoylphorbol Acetate | 1997 |
Formation of reactive oxygen species by spermatozoa from asthenospermic patients: response to treatment with pentoxifylline.
Topics: Fertilization; Humans; Infertility, Male; Male; N-Formylmethionine Leucyl-Phenylalanine; Pentoxifylline; Reactive Oxygen Species; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate | 1997 |
Tumor cell-endothelial cell interactions: evidence for roles for lipoxygenase products of arachidonic acid in metastasis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Blockade of protein kinase C is involved in the inhibition by cycloheterophyllin of neutrophil superoxide anion generation.
Topics: Animals; Arachidonic Acid; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Expression of beta 2-integrins and L-selectin on polymorphonuclear leukocytes in septic patients.
Topics: Adult; Aged; Aged, 80 and over; Calcimycin; CD18 Antigens; Female; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Severity of Illness Index; Survivors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Effects of respiratory burst inhibitors on nitric oxide production by human neutrophils.
Topics: Adenylyl Cyclases; Electrochemistry; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Humans; Hydrogen Peroxide; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Pertussis Toxin; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1997 |
Seminal reactive oxygen species and sperm motility and morphology in men with spinal cord injury.
Topics: Adult; Cross-Sectional Studies; Ejaculation; Humans; Leukocytes; Male; Masturbation; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Reference Values; Semen; Sperm Count; Sperm Motility; Sperm Tail; Spermatozoa; Spinal Cord Injuries; Tetradecanoylphorbol Acetate | 1997 |
Translocation of protein kinase C isoforms in rat neutrophils.
Topics: Animals; Biological Transport, Active; Cytosol; In Vitro Techniques; Isoenzymes; Kinetics; Membranes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effects of N-acetylcysteine on superoxide anion generation in human polymorphonuclear leukocytes.
Topics: Acetylcysteine; Anions; Calcium; Enzyme Activation; Glutathione; Humans; Lipid Peroxidation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxides; Protein Kinase C; Superoxides; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate | 1997 |
Neutrophil superoxide release and interleukin 8 in acute myocardial infarction: distinction between complicated and uncomplicated states.
Topics: Aged; Aged, 80 and over; Female; Humans; Interleukin-8; Male; Middle Aged; Myocardial Infarction; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Ozone; Streptokinase; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Peripheral blood neutrophil rheology measured by micropore filtration reflects Behçet's disease activity well.
Topics: Adolescent; Adult; Aged; Behcet Syndrome; Blood Cells; C-Reactive Protein; Female; Filtration; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Reference Values; Rheology; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Production of hydrogen peroxide by alveolar macrophages from rats exposed to subacute and chronic hypoxia.
Topics: Animals; Cell Adhesion; Hydrogen Peroxide; Hypoxia; Luminescent Measurements; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1996 |
Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways.
Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lymphocyte Activation; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate | 1997 |
Immunodepressive effects of LPS on monocyte CD14 in vivo.
Topics: Escherichia coli; Fluorescent Antibody Technique, Direct; Humans; Immunosuppressive Agents; Lipopolysaccharide Receptors; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Inhibition of neutrophil oxidative burst and granule secretion by wortmannin: potential role of MAP kinase and renaturable kinases.
Topics: Androstadienes; Antigens, CD; Antigens, Neoplasm; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molecules; Cell Degranulation; Cells, Cultured; Chromones; Enzyme Inhibitors; Humans; MAP Kinase Kinase 1; Membrane Glycoproteins; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Platelet Membrane Glycoproteins; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tetraspanin 30; Wortmannin | 1997 |
Internalization of ecto-ATPase activity in human neutrophils upon stimulation with phorbol ester or formyl peptide.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Cell Membrane; Endocytosis; Histocytochemistry; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Intracellular Membranes; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Changes of neutrophil migration without modification of in vitro metabolism and adhesion in Behçet's disease.
Topics: Adult; Behcet Syndrome; Carcinogens; Cell Adhesion; Cell Movement; Female; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Skin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1997 |
Electrogenic H+ pathway contributes to stimulus-induced changes of internal pH and membrane potential in intact neutrophils: role of cytoplasmic phospholipase A2.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cytoplasm; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Macrophages, Peritoneal; Membrane Potentials; Mice; Mice, Inbred Strains; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Patch-Clamp Techniques; Phospholipases A; Phospholipases A2; Phosphotyrosine; Proton Pumps; Sodium-Hydrogen Exchangers; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
N-6 and n-3 polyunsaturated fatty acids stimulate translocation of protein kinase Calpha, -betaI, -betaII and -epsilon and enhance agonist-induced NADPH oxidase in macrophages.
Topics: Calcimycin; Docosahexaenoic Acids; Enzyme Inhibitors; Fatty Acids, Unsaturated; Histones; HL-60 Cells; Humans; Indoles; Ionophores; Isoenzymes; Luminescent Measurements; Macrophages; Maleimides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells.
Topics: Animals; Calcimycin; Calcium; Cattle; Cell Count; Cell Separation; Corpus Luteum; Enzyme Activation; Female; Luminescent Measurements; Luteal Phase; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1997 |
Alveolar neutrophils in endotoxin-induced and bacteria-induced acute lung injury in rats.
Topics: Animals; Bronchoalveolar Lavage Fluid; Collagenases; Endotoxins; Exocytosis; Leukocyte Elastase; Lipopolysaccharides; Lung; Lung Injury; Male; Matrix Metalloproteinase 9; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pseudomonas aeruginosa; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in phosp
Topics: Androstadienes; Cell Differentiation; Cell Membrane; Chromones; Enzyme Activation; HL-60 Cells; Humans; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphodiesterase Inhibitors; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
Fenspiride and membrane transduction signals in rat alveolar macrophages.
Topics: Animals; Bronchodilator Agents; Calcium; Cell Membrane; Hydrogen-Ion Concentration; Macrophages, Alveolar; N-Formylmethionine Leucyl-Phenylalanine; Rats; Signal Transduction; Spiro Compounds; Tetradecanoylphorbol Acetate | 1997 |
Modulatory effects of the colonic milieu on neutrophil oxidative burst: a possible pathogenic mechanism of ulcerative colitis.
Topics: Adult; Colectomy; Colitis, Ulcerative; Colon; Dose-Response Relationship, Drug; Female; Humans; Lipopolysaccharides; Luminescent Measurements; Luminol; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Reactive Oxygen Species; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
The regulation by phosphorylation of 'priming' of phospholipase A2 activity in the neutrophil model system, differentiated HL60 cells.
Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Differentiation; Cell Membrane; Cytochalasin B; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Lysophospholipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1997 |
Intercellular adhesion molecule-1 and CD18 are involved in neutrophil adhesion and its cytotoxicity to cultured sinusoidal endothelial cells in rats.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Cells, Cultured; Chemotaxis, Leukocyte; Dexamethasone; Endothelium; Intercellular Adhesion Molecule-1; Liver; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Effect of the protein kinase C inhibitor GF 109 203X on elastase release and respiratory burst of human neutrophils.
Topics: Calcimycin; Calcium; Enzyme Inhibitors; Exocytosis; Humans; In Vitro Techniques; Indoles; L-Lactate Dehydrogenase; Leukocyte Elastase; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Phosphatase activity regulates superoxide anion generation and intracellular signaling in human neutrophils.
Topics: Adult; Humans; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxazoles; Phosphatidic Acids; Phospholipase D; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of superoxide production and chemotaxis by methotrexate in neutrophils primed by TNF-alpha or LPS.
Topics: Cells, Cultured; Chemotaxis, Leukocyte; Cytochrome c Group; Guanosine; Humans; Hypoxanthine; Interleukin-8; Lipopolysaccharides; Methotrexate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Effect of linoleic acid, linoleic acid anilide, and arachidonic acid on the expression of adhesion molecules on human neutrophils.
Topics: Anilides; Arachidonic Acid; CD18 Antigens; Cell Adhesion Molecules; Flow Cytometry; Humans; Integrin alphaXbeta2; L-Selectin; Linoleic Acid; Linoleic Acids; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate | 1997 |
Regulation of capacitative Ca2+ influx in human neutrophil granulocytes. Alterations in chronic granulomatous disease.
Topics: Calcium; Granulomatous Disease, Chronic; Humans; Ion Transport; Manganese; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes.
Topics: Animals; Cell Cycle Proteins; Cell Line; Cell Membrane; Cell Movement; Chimerin 1; Cytoskeleton; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Mice; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Phagocytosis; Proteins; rac GTP-Binding Proteins; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Receptors, Peptide; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Azurophilic granules of human neutrophils contain CD14.
Topics: Calcimycin; Cytoplasmic Granules; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1997 |
Local changes in membrane potential intensify neutrophil oxidative burst.
Topics: Adolescent; Adult; Electric Stimulation; Humans; In Vitro Techniques; Ionomycin; Ionophores; Luminescent Measurements; Luminol; Membrane Potentials; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Influence of SNN-6010, an elemental diet, on the generation of cytokines, NO, and chemiluminescence from leukocytes and umbilical vein endothelial cells in man.
Topics: Adult; Cells, Cultured; Cytokines; Endothelium, Vascular; Female; Food, Formulated; Humans; Leukocytes; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1997 |
Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 affinity for glucose is enhanced during the respiratory burst.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Cell Division; Cell Line; Cell Membrane; Deoxyglucose; Enzyme Inhibitors; Glucose; Glucose Transporter Type 3; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Kinetics; Macrophages; Mice; Monocytes; Monosaccharide Transport Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Lyn and Fgr are activated in distinct membrane fractions of human granulocytic cells.
Topics: Blotting, Western; Calcimycin; Cell Membrane; Cells, Cultured; Granulocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src-Family Kinases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tretinoin; Zymosan | 1997 |
Cytokine priming of the granulocyte respiratory burst in myelodysplastic syndromes.
Topics: Adult; Aged; Aged, 80 and over; Cytokines; Female; Granulocytes; Humans; Male; Middle Aged; Myelodysplastic Syndromes; N-Formylmethionine Leucyl-Phenylalanine; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Effects of brefeldin A on phosphatidylcholine phospholipase D and inositolphospholipid metabolism in HL-60 cells.
Topics: Adenosine Triphosphate; ADP-Ribosylation Factors; Brefeldin A; Cyclopentanes; Enzyme Activation; Enzyme Inhibitors; Galactosyltransferases; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phosphatidylinositols; Phospholipase D; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Acute regulation of glucose transport after activation of human peripheral blood neutrophils by phorbol myristate acetate, fMLP, and granulocyte-macrophage colony-stimulating factor.
Topics: Biological Transport; Carcinogens; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 1998 |
Potent anti-inflammatory activity of pheophytin a derived from edible green alga, Enteromorpha prolifera (Sujiao-nori).
Topics: Animals; Anti-Inflammatory Agents; Chlorophyta; Edema; Humans; In Vitro Techniques; Macrophages; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Pheophytins; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: evidence for an ERK-independent pathway.
Topics: Androstadienes; Calcium-Calmodulin-Dependent Protein Kinases; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Line, Transformed; Chromones; Complement C5a; Endothelium, Vascular; Epitopes; Humans; Ionophores; Macrophage-1 Antigen; Morpholines; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphatidylinositol 3-Kinases; Tetradecanoylphorbol Acetate; Up-Regulation; Wortmannin | 1998 |
An ultracytochemical study on the dynamics of alkaline phosphatase-positive granules in rat neutrophils.
Topics: Alkaline Phosphatase; Animals; Cerium; Cytoplasmic Granules; Male; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Cationic proteins of neutrophil azurophilic granules: protein-protein interaction and blockade of NADPH oxidase activation.
Topics: Cell Fractionation; Cell-Free System; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Gel; Cytoplasmic Granules; Cytosol; Enzyme Activation; Humans; Muramidase; Myeloblastin; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phenylmethylsulfonyl Fluoride; Respiratory Burst; Serine Endopeptidases; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Erucic acid and erucic acid anilide-induced oxidative burst in human polymorphonuclear leukocytes.
Topics: Anilides; Calcium; Dose-Response Relationship, Drug; Erucic Acids; Humans; Indoles; Intracellular Fluid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1997 |
Distinct localization of GLUT-1, -3, and -5 in human monocyte-derived macrophages: effects of cell activation.
Topics: Cell Differentiation; Cells, Cultured; Glucose Transporter Type 1; Glucose Transporter Type 3; Glucose Transporter Type 5; Humans; Macrophage Activation; Macrophages; Microscopy, Confocal; Molecular Weight; Monocytes; Monosaccharide Transport Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Tetradecanoylphorbol Acetate | 1998 |
Type II diabetics with macrovascular complications: polymorphonuclear leukocyte (PMN) filtration, PMN membrane fluidity and cytosolic Ca2+ content after activation.
Topics: Aged; Calcium; Cell Movement; Cytosol; Diabetes Mellitus, Type 2; Diphenylhexatriene; Fluorescence Polarization; Fluorescent Dyes; Fura-2; Humans; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Vascular Diseases | 1998 |
Two signaling mechanisms for activation of alphaM beta2 avidity in polymorphonuclear neutrophils.
Topics: Cell Adhesion; Enzyme Activation; GTP-Binding Proteins; Humans; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; p21-Activated Kinases; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Serine-Threonine Kinases; Receptors, Fc; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Serum of Behçet's disease enhances superoxide production of normal neutrophils.
Topics: Adult; Behcet Syndrome; Blood; Female; Humans; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1998 |
Azithromycin impact on neutrophil oxidative metabolism depends on exposure time.
Topics: Anti-Bacterial Agents; Antioxidants; Azithromycin; Cell-Free System; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Reactive Oxygen Species; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Granulocyte colony-stimulating factor promotes functional maturation of O-2 generating system during differentiation of HL-60 cells to neutrophil-like cells.
Topics: Cell Differentiation; Diglycerides; Dimethyl Sulfoxide; Enzyme Activation; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Humans; Immunoglobulin G; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Recombinant Proteins; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Zymosan | 1998 |
ADP-ribosylation factor and Rho proteins mediate fMLP-dependent activation of phospholipase D in human neutrophils.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Biological Transport; Cells, Cultured; Cytosol; Enzyme Activation; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phospholipase D; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
In vitro interaction between spiramycin and polymorphonuclear neutrophils oxidative metabolism.
Topics: Anti-Bacterial Agents; Blood Bactericidal Activity; Calcimycin; Cell Survival; Enzyme Activation; Humans; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Reactive Oxygen Species; Spiramycin; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Tachykinin receptors are present on human monocytes and play a role in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cell Separation; Female; Humans; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neurokinin A; Neurokinin B; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Nitrous oxide impairs the neutrophil oxidative response.
Topics: Adult; Anesthetics, Inhalation; Calcium; Flow Cytometry; Humans; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrous Oxide; Reactive Oxygen Species; Receptors, Peptide; Respiratory Burst; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Regulation of alphaIIb beta3 function in human B lymphocytes.
Topics: B-Lymphocytes; Cell Adhesion; Cytochalasin D; Enzyme Inhibitors; Fibrinogen; Flow Cytometry; Gene Expression Regulation; Genistein; GTP-Binding Proteins; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Physiological activation of human neutrophils down-regulates CD53 cell surface antigen.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cells, Cultured; Down-Regulation; Humans; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tetraspanin 25; Tumor Necrosis Factor-alpha | 1998 |
Dependence of neutrophil activation on cell density and adhesion.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Calcium; Cell Adhesion; Cell Count; Cells, Cultured; Drug Synergism; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Ionophores; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Different effect of diastereoisomers of L-cystathionine sulfoxide on the stimulus coupled responses of human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Metabolism, Inborn Errors; Cystathionine; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Superoxide production in human neutrophils: evidence for signal redundancy and the involvement of more than one PKC isoenzyme class.
Topics: Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Protein Kinase C; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Stimulus-dependent transduction mechanisms for nitric oxide release in human polymorphonuclear neutrophil leukocytes.
Topics: Calcimycin; Calcium; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Iatrogenic DNA damage induced in human spermatozoa during sperm preparation: protective significance of seminal plasma.
Topics: Centrifugation, Density Gradient; DNA Damage; Humans; Lipid Peroxidation; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Oligospermia; Oxidative Stress; Reactive Oxygen Species; Reproductive Techniques; Semen; Specimen Handling; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate | 1998 |
Role of cyclic adenosine monophosphate in reducing superoxide anion generation in guinea pig alveolar macrophages.
Topics: Animals; Carcinogens; Cilostazol; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Guinea Pigs; Isoenzymes; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Phosphodiesterase Inhibitors; Specific Pathogen-Free Organisms; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides | 1998 |
Release of a leukocyte activation inhibitor by staurosporine-treated pulmonary artery endothelial cells.
Topics: Animals; Biological Factors; Calcimycin; Cattle; Cell Adhesion; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Diethylcarbamazine; Endothelium, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptidyl-Dipeptidase A; Protein Kinase C; Pulmonary Artery; Rabbits; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Effect of various agonists on nitric oxide generation by human polymorphonuclear leukocytes.
Topics: Concanavalin A; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1998 |
Expression of protein kinase C isozymes in human basophils: regulation by physiological and nonphysiological stimuli.
Topics: Antibodies, Anti-Idiotypic; Basophils; Biological Transport; Calcium; Carbazoles; Cell Membrane; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Histamine Release; Humans; Indoles; Ionomycin; Ionophores; Isoenzymes; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Activation of the neutrophil respiratory burst requires both intracellular and extracellular calcium.
Topics: Calcium; Egtazic Acid; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Vanadates | 1997 |
Neutrophils deficient in PU.1 do not terminally differentiate or become functionally competent.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chemotaxis, Leukocyte; Cytoplasmic Granules; DNA-Binding Proteins; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Interferon Regulatory Factors; Interleukin-8; Macrophage Colony-Stimulating Factor; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phagocytosis; Phenotype; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Trans-Activators | 1998 |
Production of hydrogen peroxide by peritoneal macrophages from rats exposed to subacute and chronic hypoxia.
Topics: Animals; Hydrogen Peroxide; Hypoxia; Luminescent Measurements; Luminol; Macrophages, Peritoneal; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
A CD18/ICAM-1-dependent pathway mediates eosinophil adhesion to human bronchial epithelial cells.
Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Chemokine CCL11; Chemokine CCL4; Chemokine CCL5; Chemokines, CC; Complement C5a; Cytokines; Eosinophils; Epithelial Cells; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Kinetics; Leukotriene B4; Lung; Macrophage Inflammatory Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils.
Topics: Amino Acid Sequence; Antibodies; Blotting, Western; Cyclooxygenase 2; Epitopes; Escherichia coli; Gene Expression Regulation, Enzymologic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha; Zymosan | 1998 |
Effect of trifluoromethyl ketone-based elastase inhibitors on neutrophil function in vitro.
Topics: Cell Survival; Cells, Cultured; Humans; Kinetics; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oligopeptides; Pyrroles; Serine Proteinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Extracellular Ca2+ regulates the respiratory burst of human neutrophils.
Topics: Calcium; Cytosol; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Analysis of choline and phosphorylcholine content in human neutrophils stimulated by f-Met-Leu-Phe and phorbol myristate acetate: contribution of phospholipase D and C.
Topics: Choline; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphatidic Acids; Phospholipase D; Phosphorylcholine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Effect of pyridoxal 5'-phosphate on human neutrophil respiratory burst and adhesion on serum coated microplates.
Topics: Adult; Animals; Blood; Cattle; Cell Adhesion; Concanavalin A; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pyridoxal Phosphate; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Age-associated differences in neutrophil oxidative burst (chemiluminescence).
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Candida albicans; Carcinogens; Humans; Luminescent Measurements; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polyanetholesulfonate; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 1998 |
Selective role for beta-protein kinase C in signaling for O-2 generation but not degranulation or adherence in differentiated HL60 cells.
Topics: Biological Transport; Cell Adhesion; Cell Degranulation; Cell Differentiation; Fibronectins; HL-60 Cells; Humans; Isoenzymes; Ligands; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oligonucleotides, Antisense; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Interleukin-8 priming of human neutrophils is not associated with persistently altered calcium fluxes but is additive with lipopolysaccharide.
Topics: Analysis of Variance; Calcium; Complement C5a; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Hydrogen Peroxide; In Vitro Techniques; Interleukin-8; Kinetics; Lipopolysaccharides; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Phosphorylation of cytosolic phospholipase A2 by IL-3 is associated with increased free arachidonic acid generation and leukotriene C4 release in human basophils.
Topics: Arachidonic Acid; Basophils; Cells, Cultured; Complement C5a; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-3; Ionomycin; Ionophores; Leukotriene C4; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Involvement of tyrosine kinases, Ca2+ and PKC in activation of mitogen-activated protein (MAP) kinase in human polymorphonuclear neutrophils.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Enzyme Activation; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1998 |
Suppressive effects of interleukin-10 on human mononuclear phagocyte function against Candida albicans and Staphylococcus aureus.
Topics: Candida albicans; Cells, Cultured; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Interleukin-10; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Modes of action of aspirin-like drugs: salicylates inhibit erk activation and integrin-dependent neutrophil adhesion.
Topics: Acetaminophen; Antigens, CD; Arachidonic Acid; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; CD18 Antigens; Cell Adhesion; Cell Aggregation; Cell Survival; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Macrophage-1 Antigen; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sodium Salicylate; Tetradecanoylphorbol Acetate | 1998 |
Involvement of cyclic AMP generation in the inhibition of respiratory burst by 2-phenyl-4-quinolone (YT-1) in rat neutrophils.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Calcium; Carbazoles; Cardiotonic Agents; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytosol; Indoles; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Pyrroles; Quinolones; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Functional responses of neonatal chicken and turkey heterophils following stimulation by inflammatory agonists.
Topics: Animals; Calcium; Cell Adhesion; Chickens; Immunity, Innate; Inflammation; Ionomycin; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Poultry Diseases; Respiratory Burst; Tetradecanoylphorbol Acetate; Turkeys | 1998 |
Isolation and characterization of a variant HL60 cell line defective in the activation of the NADPH oxidase by phorbol myristate acetate.
Topics: Androstadienes; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; HL-60 Cells; Humans; Isoenzymes; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella; Wortmannin | 1998 |
Lysophosphatidylcholine generates superoxide anions through activation of phosphatidylinositol 3-kinase in human neutrophils.
Topics: Androstadienes; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 1998 |
Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production.
Topics: Androstadienes; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cytokines; Drug Synergism; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin | 1999 |
Priming of human neutrophils by peroxynitrite: potential role in enhancement of the local inflammatory response.
Topics: Antioxidants; Blood Proteins; Calcium; Cells, Cultured; Humans; Inflammation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrates; Oxidants; Pyrimidines; Pyrrolidines; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Calyculin A modulates activation of the NADPH-oxidase in Me2SO-differentiated HL-60 cells.
Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Inhibitors; HL-60 Cells; Humans; Marine Toxins; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxazoles; Oxygen; Phosphoprotein Phosphatases; Phosphoproteins; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Oxidative modification of high-density lipoprotein 3 induced by human polymorphonuclear neutrophils. Protective effect of pentoxifylline.
Topics: Antioxidants; Apolipoprotein A-I; Dose-Response Relationship, Drug; Humans; Lipoproteins, HDL; Lipoproteins, HDL3; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Pentoxifylline; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Vitamin E | 1999 |
Diabetes mellitus: polymorphonuclear leukocyte (PMN) filtration parameters and PMN membrane fluidity after chemotactic activation.
Topics: Adolescent; Adult; Aged; Chemotaxis, Leukocyte; Diabetes Mellitus; Filtration; Humans; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 1999 |
Role of Ca2+-ATPase inhibitors in activation of cytosolic phospholipase A2 in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Calcium-Transporting ATPases; Cell-Free System; Chelating Agents; Cytosol; DNA, Complementary; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lipid Metabolism; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Binding; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; U937 Cells | 1999 |
Essential hypertension: leukocyte rheology and polymorphonuclear cytosolic Ca2+ content at baseline and after activation.
Topics: Adult; Aged; Calcium; Chemotactic Factors; Chemotaxis, Leukocyte; Female; Hemorheology; Humans; Hypertension; Leukocytes; Male; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Smoking; Tetradecanoylphorbol Acetate; Ultrafiltration | 1998 |
The MultiScreen filtration system to measure chemoattractant-induced release of leukocyte granule enzymes by differentiated HL-60 cells or normal human monocytes.
Topics: Cell Differentiation; Chemokine CCL11; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemokine CXCL1; Chemokines; Chemokines, CC; Chemokines, CXC; Chemotactic Factors; Complement C5a; Cytokines; Cytoplasmic Granules; Filtration; Growth Substances; HL-60 Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-8; Macrophage Inflammatory Proteins; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Reference Standards; Tetradecanoylphorbol Acetate | 1999 |
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
A functional granulocyte colony-stimulating factor receptor is required for normal chemoattractant-induced neutrophil activation.
Topics: Actins; Animals; Antigens, CD; Calcium; Cell Adhesion; Cell Degranulation; Chemokine CXCL2; Chemokines; Chemotactic Factors; Chemotaxis, Leukocyte; Collagenases; Interleukin-8; Matrix Metalloproteinase 9; Mice; Mice, Mutant Strains; Monokines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Receptors, Granulocyte Colony-Stimulating Factor; Receptors, Interleukin; Receptors, Interleukin-8A; Skin; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Differential regulation of beta1 integrins by chemoattractants regulates neutrophil migration through fibrin.
Topics: Antibodies; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Fibrin; Humans; Integrin beta1; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1999 |
Activation of the granule pool of the NADPH oxidase accelerates apoptosis in human neutrophils.
Topics: Apoptosis; DNA Fragmentation; Enzyme Activation; HL-60 Cells; Humans; Hydrogen Peroxide; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophil Activation; Neutrophils; Oxidative Stress; Tetradecanoylphorbol Acetate | 1999 |
Heterogeneity in F-actin polymerization of cord blood polymorphonuclear leukocytes stimulated by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Actins; Adult; Age Factors; Chemotaxis, Leukocyte; Female; Fetal Blood; Flow Cytometry; Humans; Infant, Newborn; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymers; Tetradecanoylphorbol Acetate | 1999 |
Characteristics of the production of active oxygen species from adherent and non-adherent neutrophils.
Topics: Cell Adhesion; Cells, Cultured; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Fibronectins; Humans; Interleukin-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polystyrenes; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors; Umbilical Veins | 1999 |
High oxygen radical production is associated with fast parasite clearance in children with Plasmodium falciparum malaria.
Topics: Child; Child, Preschool; Female; Free Radicals; Gabon; Granulocytes; Humans; Infant; Malaria, Falciparum; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Singlet Oxygen; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
2-Hydroxymethyl-1-naphthol diacetate (TAC) suppresses the superoxide anion generation in rat neutrophils.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cyclic AMP; Cytochalasin B; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADPH Dehydrogenase; NADPH Oxidases; Naphthols; Neutrophils; Oxygen Consumption; Phospholipase D; Phosphoproteins; Protein Kinase C; Rats; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Effect of water extracts of Rhizopus delemar on the stimulus coupled responses of neutrophils and their modulation by various protein kinase inhibitors.
Topics: Enzyme Inhibitors; Genistein; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Protein Kinase Inhibitors; Rhizopus; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Water | 1999 |
[Hyperthermia-induced priming effect in neutrophil granulocytes].
Topics: Complement C5a; Humans; Hyperthermia, Induced; In Vitro Techniques; Infrared Rays; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Whole-Body Irradiation | 1999 |
Modulation of C3a activity: internalization of the human C3a receptor and its inhibition by C5a.
Topics: Acids; Buffers; Cell Differentiation; Cell Line; Complement C3a; Complement C5a; Complement Inactivator Proteins; Dose-Response Relationship, Immunologic; Flow Cytometry; Humans; Interferon-gamma; Iodine Radioisotopes; Leukemia, Myelomonocytic, Acute; Ligands; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Tetradecanoylphorbol Acetate; U937 Cells; Virulence Factors, Bordetella | 1999 |
Activation of the neutrophil NADPH oxidase is inhibited by SB 203580, a specific inhibitor of SAPK2/p38.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils.
Topics: Androstadienes; Chromones; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Indoles; Leukotriene B4; Maleimides; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin | 1999 |
Effect of steroidal saponins of Anemarrhenae rhizoma on superoxide generation in human neutrophils.
Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prednisolone; Saponins; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Intracellular free calcium regulates the onset of the respiratory burst of human neutrophils activated by phorbol myristate acetate.
Topics: Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intracellular Fluid; Mitogens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Signal transduction pathways in normal human monocytes stimulated by cytokines and mediators: comparative study with normal human neutrophils or transformed cells and the putative roles in functionality and cell biology.
Topics: Adult; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Cytokines; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Milk Proteins; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotyrosine; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Superoxides; Tetradecanoylphorbol Acetate; Trans-Activators | 1999 |
The ketolide antimicrobial agent HMR-3004 inhibits neutrophil superoxide production by a membrane-stabilizing mechanism.
Topics: Adult; Anti-Bacterial Agents; Cell Membrane; Humans; Ketolides; Lysophosphatidylcholines; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Simultaneous analysis of eosinophil and neutrophil adhesion to plasma and tissue fibronectin, fibrinogen, and albumin.
Topics: Cell Adhesion; Eosinophils; Fibrinogen; Fibronectins; Granulocytes; Humans; In Vitro Techniques; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plasma; Radioimmunoassay; Serum Albumin; Tetradecanoylphorbol Acetate | 1999 |
Differential fMet-Leu-Phe- and platelet-activating factor-induced signaling toward Ral activation in primary human neutrophils.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinase 1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Proteins; ral GTP-Binding Proteins; rap GTP-Binding Proteins; ras GTPase-Activating Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
Chemistry and biological activities of constituents from Morus australis.
Topics: Animals; Cell Degranulation; Cytochalasin B; Flavonoids; Magnetic Resonance Spectroscopy; Mast Cells; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Aggregation Inhibitors; Rats; Taiwan; Tetradecanoylphorbol Acetate; Trees | 1999 |
Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.
Topics: Amino Acid Sequence; Antigen-Antibody Complex; Carbazoles; Cell Adhesion; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Macrophage-1 Antigen; Membrane Glycoproteins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyrroles; Receptors, IgG; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Diverse effects of neutrophil integrin occupation on respiratory burst activation.
Topics: Antibodies; Antigens, CD; Cells, Cultured; Concanavalin A; Cytochalasin B; Down-Regulation; Fibronectins; Humans; Integrin beta3; Integrins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Protein Kinases; Receptor Aggregation; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1999 |
Priming of the neutrophil respiratory burst is species-dependent and involves MAP kinase activation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Humans; Mice; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Rabbits; Rats; Respiratory Burst; Signal Transduction; Species Specificity; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Effect of aging on CD11b and CD69 surface expression by vesicular insertion in human polymorphonuclear leucocytes.
Topics: Adult; Aged; Aging; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD11 Antigens; Cell Culture Techniques; Dose-Response Relationship, Immunologic; Exocytosis; Female; Humans; Lectins, C-Type; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 1999 |
[Post-receptor formation of active forms of oxygen in nonphagocytic cells].
Topics: Animals; Cell Line; Epidermal Growth Factor; ErbB Receptors; Interferon-gamma; Lipopolysaccharides; Mice; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Platelet Activating Factor; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Synovial PMN show a coordinated up-regulation of CD66 molecules.
Topics: Adult; Aged; Alprostadil; Antigens, CD; Antigens, Differentiation; Arthritis; Arthritis, Psoriatic; Arthritis, Reactive; Arthritis, Rheumatoid; CD59 Antigens; Cell Adhesion Molecules; Dinoprostone; Female; Flow Cytometry; Gene Expression Regulation; Glycosylphosphatidylinositols; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Isoforms; Receptors, IgG; Synovial Fluid; Tetradecanoylphorbol Acetate | 1999 |
Priming of superoxide anion in polymorphonuclear neutrophils by brain natriuretic peptide.
Topics: Animals; Cell Separation; Cell Survival; Cells, Cultured; Drug Synergism; Humans; N-Formylmethionine Leucyl-Phenylalanine; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Neutrophils; Peptide Fragments; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
Essential hypertension: polymorphonuclear leukocyte membrane fluidity at baseline and after chemotactic activation.
Topics: Adult; Aged; Blood Pressure; Chemotactic Factors; Female; Humans; Hypertension; Male; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 1999 |
Heparin-binding protein targeted to mitochondrial compartments protects endothelial cells from apoptosis.
Topics: Antimicrobial Cationic Peptides; Apoptosis; Biological Transport; Blood Proteins; Carrier Proteins; Cells, Cultured; Chromatography, Affinity; Endothelium, Vascular; Heparin; Humans; Kinetics; Leukotriene B4; Mitochondria; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proteoglycans; Recombinant Proteins; Tetradecanoylphorbol Acetate; Umbilical Veins | 1999 |
Effects of milk and colostrum on superoxide generation of oral polymorphonuclear neutrophils and the changes that occur during storage at low temperature.
Topics: Animals; Cold Temperature; Colostrum; Fatty Acids; Fatty Acids, Nonesterified; Female; Humans; Milk; Mouth; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1999 |
The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions.
Topics: Calcitriol; Calcium; Calcium Channel Agonists; Cell Differentiation; Dimethyl Sulfoxide; Down-Regulation; Enzyme Inhibitors; Gene Products, nef; HL-60 Cells; Humans; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src Homology Domains; src-Family Kinases; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 1999 |
'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils.
Topics: Androstadienes; Carbazoles; CD18 Antigens; Cell Adhesion; Cell Count; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Humans; Imidazoles; Indoles; Isoenzymes; Macrophage-1 Antigen; Maleimides; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyridines; Pyrimidines; Signal Transduction; src-Family Kinases; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 1999 |
Tyrosine and calcium/calmodulin kinases are common signaling components in the generation of reactive oxygen species in human lymphocytes.
Topics: Aminoquinolines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catalase; Cinnamates; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Lymphocyte Activation; Lymphocytes; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Protein-Tyrosine Kinases; Reactive Oxygen Species; Signal Transduction; Sodium Azide; Sulfides; Tetradecanoylphorbol Acetate; Tyrphostins | 1999 |
Selective inhibition of protein kinase C, mitogen-activated protein kinase, and neutrophil activation in response to calcium pyrophosphate dihydrate crystals, formyl-methionyl-leucyl-phenylalanine, and phorbol ester by O-(chloroacetyl-carbamoyl) fumagillo
Topics: Calcium Pyrophosphate; Carcinogens; Cyclohexanes; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; O-(Chloroacetylcarbamoyl)fumagillol; Phosphatidylinositol 3-Kinases; Protein Kinase C; Sesquiterpenes; Tetradecanoylphorbol Acetate | 1999 |
Effects of local anesthetics on phospholipase D activity in differentiated human promyelocytic leukemic HL60 cells.
Topics: Anesthetics, Local; Biological Transport; Cell Differentiation; Cell Membrane; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Recombinant Proteins; Tetracaine; Tetradecanoylphorbol Acetate | 1999 |
Tyrosine kinase-regulated small GTPase translocation and the activation of phospholipase D in HL60 granulocytes.
Topics: ADP-Ribosylation Factors; Cinnamates; Drug Synergism; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Sulfides; Tetradecanoylphorbol Acetate; Tyrosine; Vanadium Compounds | 1999 |
[Functional heterogeneity of polymorphonuclear leukocytes population in peripheral blood of patients with acute dysentery].
Topics: Acute Disease; Adolescent; Adult; Dysentery, Bacillary; Humans; Lipopolysaccharides; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prognosis; Severity of Illness Index; Shigella flexneri; Tetradecanoylphorbol Acetate; Zymosan | 1999 |
Ultracytochemical study on the localization of superoxide producing sites in stimulated rat neutrophils.
Topics: Animals; Cytochalasin B; Cytoplasmic Granules; Endosomes; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peritoneal Cavity; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
DNA damage in human leukocytes after ischemia/reperfusion injury.
Topics: Adult; Arm; Chemotaxis, Leukocyte; DNA Damage; Humans; Ischemia; Lactates; Leg; Leukocyte Count; Leukocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Reperfusion Injury; Respiratory Burst; Tetradecanoylphorbol Acetate; Tourniquets | 2000 |
Genistein augments prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chlorides; Cyclic GMP; Dinoprostone; Drug Synergism; Electric Impedance; Female; Genistein; Ileum; Intestinal Mucosa; Ischemia; Male; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Swine; Tetradecanoylphorbol Acetate; Tritium | 2000 |
Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells.
Topics: Actins; Adenosine Diphosphate; Apoptosis; Blood Platelets; Cell Survival; Cytochalasin B; Cytoskeleton; Dinoprost; fas Receptor; Humans; In Vitro Techniques; Kinetics; Leukocytes; Lymphocytes; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; Necrosis; Point Mutation; Proteins; Reference Values; src Homology Domains; Tetradecanoylphorbol Acetate; Thrombocytopenia; Wiskott-Aldrich Syndrome; Wiskott-Aldrich Syndrome Protein | 2000 |
Effects of the solvent 1,2,4-trimethylcyclohexane on respiratory burst in human neutrophil granulocytes. A chemiluminescence and electron paramagnetic resonance spectrometry study.
Topics: Cyclohexanes; Electron Spin Resonance Spectroscopy; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphodiesterase Inhibitors; Respiratory Burst; Solvents; Tetradecanoylphorbol Acetate | 1999 |
Neurosedative and antioxidant activities of phenylpropanoids from ballota nigra.
Topics: Animals; Antioxidants; Catechols; Enzyme Activation; Female; Humans; Hypnotics and Sedatives; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; L-Lactate Dehydrogenase; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Plants, Medicinal; Protein Kinase C; Rats; Receptors, Dopamine; Receptors, GABA-A; Receptors, Opioid; Spectrophotometry, Ultraviolet; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Differential regulation of Ca2+ influx by fMLP and PAF in human neutrophils: possible involvement of store-operated Ca2+ channel.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cyclic GMP; Egtazic Acid; Enzyme Activation; Humans; Imidazoles; Loperamide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 2000 |
Effects of selective protein kinase C inhibitors on the proteolytic down-regulation of L-selectin from chemoattractant-activated neutrophils.
Topics: Acetophenones; Antigens, CD; Benzopyrans; Cells, Cultured; Chemotactic Factors; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dipeptides; Down-Regulation; Humans; Hydroxamic Acids; L-Selectin; Metalloendopeptidases; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Neutrophil Activation; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate | 2000 |
Increased expression of matrix metalloproteinase-9 in neutrophils in glycogen-induced peritoneal inflammation of guinea pigs.
Topics: Animals; Cycloheximide; Dactinomycin; Gene Expression; Glycogen; Guinea Pigs; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nucleic Acid Synthesis Inhibitors; Peritonitis; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
Superoxide release and superoxide dismutase expression by human gingival fibroblasts.
Topics: Analysis of Variance; Blotting, Northern; Calcium; Cell Wall; Cells, Cultured; Cytokines; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gingiva; Humans; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytes; Reactive Oxygen Species; Respiratory Burst; Streptococcus; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Topics: Amino Acid Sequence; Animals; Arachidonate 5-Lipoxygenase; Arsenites; Calcimycin; Cell Line; Cricetinae; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sodium Compounds; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Necrosis Factor-alpha | 2000 |
Study of eosinophil-endothelial adhesion, production of oxygen radicals and release of eosinophil cationic protein by peripheral blood eosinophils of patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Autoimmune Diseases; Blood Proteins; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Eosinophil Granule Proteins; Eosinophils; Female; Humans; Inflammation; Interleukin-1; Macrophage-1 Antigen; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Ribonucleases; Tetradecanoylphorbol Acetate; Umbilical Cord | 1993 |
The oxidative metabolism of circulating phagocytes in ankylosing spondylitis: determination by whole blood chemiluminescence.
Topics: Adult; Blood Sedimentation; C-Reactive Protein; Humans; Luminescent Measurements; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Spondylitis, Ankylosing; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Diazepam-binding inhibitor-derived peptides induce intracellular calcium changes and modulate human neutrophil function.
Topics: Antineoplastic Agents; Benzodiazepinones; Calcium; Chemotaxis, Leukocyte; Cytosol; Humans; Hypolipidemic Agents; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neuropeptides; Neutrophils; Peptide Fragments; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Oxidative metabolism and release of myeloperoxidase from polymorphonuclear leukocytes obtained from blood sedimentation in a Ficoll-Hypaque gradient.
Topics: Acridines; Blood Sedimentation; Chemistry, Clinical; Cytochalasin B; Diatrizoate; Ficoll; Humans; Hydrogen Peroxide; Indicators and Reagents; Leukocytes, Mononuclear; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Reactive Oxygen Species; Reproducibility of Results; Tetradecanoylphorbol Acetate; Zymosan | 2000 |
Oxidative burst measurement in patients treated with cytostatics: influence of G-CSF and role as a prognostic factor.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Dexamethasone; Escherichia coli; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Prognosis; Respiratory Burst; Tetradecanoylphorbol Acetate | 2000 |
Basic fibroblast growth factor modulates the surface expression of effector cell molecules and primes respiratory burst activity in human neutrophils.
Topics: Adult; Antibodies, Monoclonal; Cell Adhesion Molecules; Fibroblast Growth Factor 2; Flow Cytometry; Humans; Hydrogen Peroxide; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Complement; Respiratory Burst; Tetradecanoylphorbol Acetate | 2000 |
Regulation of the release of eosinophil cationic protein by eosinophil adhesion.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Blood Proteins; CD18 Antigens; Cell Adhesion; Cell Death; Cell Degranulation; Dextrans; Eosinophil Granule Proteins; Eosinophils; Gene Expression Regulation; Humans; Integrin alpha4; Manganese; Mice; N-Formylmethionine Leucyl-Phenylalanine; Opsonin Proteins; Ribonucleases; Tetradecanoylphorbol Acetate | 2000 |
Modulation of neutrophil migration and superoxide anion release by metoprolol.
Topics: Adrenergic beta-Antagonists; Cells, Cultured; Chemotaxis, Leukocyte; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Metoprolol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Respiratory Burst; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Nitric oxide regulates the aggregation of stimulated human neutrophils.
Topics: Actins; Antibodies; Arginine; CD18 Antigens; Cell Aggregation; Cyclic GMP; Cytochalasin B; Drug Synergism; Flow Cytometry; Humans; L-Selectin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Tetradecanoylphorbol Acetate | 2000 |
Polymorphonuclear leukocyte membrane fluidity before and after activation in subjects with insulin resistance.
Topics: Adolescent; Adult; Child; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hyperinsulinism; In Vitro Techniques; Insulin Resistance; Male; Membrane Fluidity; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Obesity; Reference Values; Tetradecanoylphorbol Acetate | 2000 |
The effect of a Rho kinase inhibitor Y-27632 on superoxide production, aggregation and adhesion in human polymorphonuclear leukocytes.
Topics: Adult; Amides; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Superoxides; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition.
Topics: Calcimycin; Catalysis; Cell Degranulation; Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Immunohistochemistry; Inflammation Mediators; Membrane Proteins; Molecular Weight; Myeloblastin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Osmolar Concentration; Protein Binding; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium Chloride; Tetradecanoylphorbol Acetate | 2000 |
Usefulness of grading of neutrophil aggregate size by laser-light scattering technique for characterizing stimulatory and inhibitory effects of agents on aggregation.
Topics: Androstadienes; Bucladesine; Cell Aggregation; Cell Count; Cytochalasin B; Dinoprostone; Enzyme Activators; Enzyme Inhibitors; Humans; Lasers; Light; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Particle Size; Phorbol Esters; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Scattering, Radiation; Tetradecanoylphorbol Acetate; Wortmannin | 2000 |
The effects of aliphatic (n-nonane), naphtenic (1,2, 4-trimethylcyclohexane), and aromatic (1,2,4-trimethylbenzene) hydrocarbons on respiratory burst in human neutrophil granulocytes.
Topics: 1-Butanol; Alkanes; Benzene Derivatives; Calcium; Cells, Cultured; Cyclic N-Oxides; Cyclohexanes; Ditiocarb; Electron Spin Resonance Spectroscopy; Estrenes; Humans; Hydroxylation; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Onium Compounds; Pyrrolidinones; Respiratory Burst; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 2000 |
Prostasomes inhibit the NADPH oxidase activity of human neutrophils.
Topics: Cholesterol; Fluorescent Dyes; Humans; Imidazoles; Luminescent Measurements; Male; Membrane Fluidity; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phospholipids; Prostate; Pyrazines; Reactive Oxygen Species; Secretory Vesicles; Semen; Spermatozoa; Temperature; Tetradecanoylphorbol Acetate | 2000 |
Influence of disease site and activity on peripheral neutrophil function in inflammatory bowel disease.
Topics: Adult; Colitis, Ulcerative; Crohn Disease; Female; Humans; Ileal Diseases; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 2000 |
Effects of 2-ethylhexanoic acid on the production of reactive oxygen species in human polymorphonuclear leukocytes in vitro.
Topics: Caproates; Cell Survival; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2000 |
Cartilage degradation by stimulated human neutrophils: reactive oxygen species decrease markedly the activity of proteolytic enzymes.
Topics: Animals; Arthritis, Rheumatoid; Biphenyl Compounds; Cartilage, Articular; Culture Media, Conditioned; Cytochalasin B; Endopeptidases; Humans; In Vitro Techniques; Luminescent Measurements; Magnetic Resonance Spectroscopy; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Onium Compounds; Proteoglycans; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tetradecanoylphorbol Acetate | 2000 |
Inhibition of human peripheral blood neutrophil respiratory burst by alcohol-based venipuncture site disinfection.
Topics: 1-Propanol; 2-Propanol; Alcohols; Disinfectants; Ethanol; Fluoresceins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phlebotomy; Respiratory Burst; Tetradecanoylphorbol Acetate | 2000 |
Activation-dependent proteolytic degradation of polymorphonuclear CD11b.
Topics: Antibodies, Monoclonal; Blotting, Western; Cell Adhesion; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hyaluronan Receptors; Macrophage-1 Antigen; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peptide Hydrolases; Platelet Factor 4; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Activation of human neutrophils with chemotactic peptide, opsonized zymosan and the calcium ionophore A23187, but not with a phorbol ester, is accompanied by efflux and store-operated influx of calcium.
Topics: Calcimycin; Calcium; Fluorescent Dyes; Fura-2; Humans; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 2000 |
Activity of artichoke leaf extract on reactive oxygen species in human leukocytes.
Topics: Antioxidants; Asteraceae; Caffeic Acids; Chlorogenic Acid; Cinnamates; Flavonoids; Flow Cytometry; Humans; Hydrogen Peroxide; In Vitro Techniques; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidative Stress; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2000 |
Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammation.
Topics: Animals; Cell Degranulation; Cytoplasmic Granules; Disease Models, Animal; Eosinophils; Exocytosis; Humans; Hypersensitivity; In Vitro Techniques; Inflammation; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Nasal Septum; Ovalbumin; Peroxidases; Respiratory Mucosa; Tetradecanoylphorbol Acetate | 2001 |
Nutritional lipid emulsions modulate cellular signaling and activation of human neutrophils.
Topics: Blood; Calcium; Cytosol; Emulsions; Estrenes; Fluorescent Dyes; Fura-2; Humans; Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphodiesterase Inhibitors; Protein Kinase C; Pyrrolidinones; Signal Transduction; Spectrometry, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases; Zymosan | 2001 |
Evaluation of red blood cell lysing solutions in the study of neutrophil oxidative burst by the DCFH assay.
Topics: Cell Membrane; Cell Survival; Cells, Cultured; Flow Cytometry; Hemolysis; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Yersinia enterocolitica | 2001 |
Inhibitory effect of serine protease inhibitors on neutrophil-mediated endothelial cell injury.
Topics: Cells, Cultured; Drug Combinations; Endothelium, Vascular; Flow Cytometry; Glycine; Glycoproteins; Humans; Interferon-gamma; Interleukin-1; Intracellular Fluid; Leukocyte Elastase; Lipopolysaccharides; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Serine Proteinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate; Trypsin Inhibitors; Tumor Necrosis Factor-alpha; Umbilical Veins | 2001 |
Effect of five flavonoid compounds isolated from Quercus dentata Thunb on superoxide generation in human neutrophils and phosphorylation of neutrophil proteins.
Topics: Flavonoids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Rosales; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils.
Topics: Choline; Chromatography, Thin Layer; Diglycerides; Drug Interactions; Ethanol; Ethanolamine; Glycerophosphates; Glycerophospholipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Generation of reactive oxygen species by equine spermatozoa.
Topics: Animals; Calcimycin; Catalase; Centrifugation, Density Gradient; Cryopreservation; Horses; Hydrogen Peroxide; Ionophores; Male; Microscopy, Interference; N-Formylmethionine Leucyl-Phenylalanine; NADP; Reactive Oxygen Species; Semen Preservation; Spermatozoa; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
A potential role for annexin 1 as a physiologic mediator of glucocorticoid-induced L-selectin shedding from myeloid cells.
Topics: Animals; Annexins; Cattle; Cell Size; Dexamethasone; Dose-Response Relationship, Immunologic; Down-Regulation; Flow Cytometry; Humans; L-Selectin; Leukocytes; Metalloendopeptidases; Myeloid Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Tetradecanoylphorbol Acetate | 2001 |
Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils.
Topics: Androstadienes; Animals; Antibody Specificity; Antigen-Antibody Reactions; Enzyme Activation; Guinea Pigs; Immune Sera; Kinetics; Marine Toxins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Oxazoles; Oxidative Stress; p21-Activated Kinases; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Rabbits; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Evaluation of the use of the solvent dimethyl sulfoxide in chemiluminescent studies.
Topics: Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Humans; Immunomagnetic Separation; Leukocytes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Solvents; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2000 |
Age-related changes in membrane lipid composition, fluidity and respiratory burst in rat peritoneal neutrophils.
Topics: Aging; Animals; Cholesterol; Cholesterol Esters; Diglycerides; Fatty Acids; Female; Glucosephosphate Dehydrogenase; Membrane Fluidity; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Pentose Phosphate Pathway; Peritoneal Cavity; Phosphogluconate Dehydrogenase; Phospholipids; Rats; Rats, Wistar; Respiratory Burst; Tetradecanoylphorbol Acetate | 2001 |
The water-soluble components of the essential oil of Melaleuca alternifolia (tea tree oil) suppress the production of superoxide by human monocytes, but not neutrophils, activated in vitro.
Topics: Anti-Infective Agents, Local; Cells, Cultured; Cyclohexane Monoterpenes; Cyclohexanols; Cyclohexenes; Eucalyptol; Humans; Lipopolysaccharides; Menthol; Monocytes; Monoterpenes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Solubility; Superoxides; Tea Tree Oil; Terpenes; Tetradecanoylphorbol Acetate; Water | 2001 |
Human blood platelets, PMN leukocytes and their interactions in vitro. Responses to selective and non-selective stimuli.
Topics: Adult; Blood Platelets; Calcimycin; Cell Communication; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 2000 |
Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells.
Topics: Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Cytochrome c Group; Cytosol; Dihydrolipoamide Dehydrogenase; Dose-Response Relationship, Drug; Electron Transport; Electrons; Enzyme Activation; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Membrane Glycoproteins; Models, Biological; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Phenotype; Phospholipases A; Superoxides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Time Factors | 2001 |
Inhibition of neutrophil responses by cyclosporin A. An insight into molecular mechanisms.
Topics: Binding, Competitive; Calcium; Caseins; Cell Degranulation; Cell Survival; Chemotaxis; Cyclosporine; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Peptide; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Effect of nitrite on endothelial function in isolated lung.
Topics: Animals; Blood Pressure; Capillary Permeability; Carcinogens; Dimethyl Sulfoxide; Endothelium, Vascular; Free Radical Scavengers; Lipopolysaccharides; Lung; Male; Models, Animal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrites; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Tyrosine | 2000 |
A novel method for isolation of neutrophils from murine blood using negative immunomagnetic separation.
Topics: Animals; CD18 Antigens; Cell Survival; Chemotaxis, Leukocyte; Flow Cytometry; Immunomagnetic Separation; In Vitro Techniques; L-Selectin; Leukocyte Transfusion; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reproducibility of Results; Tetradecanoylphorbol Acetate; Venules | 2001 |
Effect of three flavonoids, 5,7,3',4'-tetrahydroxy-3-methoxy flavone, luteolin, and quercetin, on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophil.
Topics: Arachidonic Acid; Blood Proteins; Flavonoids; Humans; In Vitro Techniques; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Quercetin; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2001 |
A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.
Topics: Antibodies, Monoclonal; Antibody Specificity; Biomarkers; Blotting, Western; CD18 Antigens; Cell Adhesion; Electrophoresis, Gel, Two-Dimensional; Endopeptidases; Epitopes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoglobulin G; Lipopolysaccharides; Male; Mass Spectrometry; Monocytes; Myeloid Cells; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
PAF receptor antagonist modulates neutrophil responses with thermal injury in vivo.
Topics: Animals; Burns; Calcium; Carcinogens; Male; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Hypertonic saline activation of p38 MAPK primes the PMN respiratory burst.
Topics: Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; p38 Mitogen-Activated Protein Kinases; Pyridines; Respiratory Burst; Saline Solution, Hypertonic; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Rapid fusion of granules with neutrophil cell membranes in hypertensive patients may increase vascular damage.
Topics: Adult; Albuminuria; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blood Vessels; Calpain; Carcinogens; Cell Fusion; Cell Membrane; Cysteine Proteinase Inhibitors; Cytoplasmic Granules; Enzyme Inhibitors; Female; Humans; Hypertension; Indoles; Lectins, C-Type; Leucine; Lipids; Macrophage-1 Antigen; Male; Maleimides; Metabolic Syndrome; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 2001 |
[Production and secretion of interleukin 6 from stimulated peritoneal macrophages of the mouse].
Topics: Animals; Calcimycin; Calcium Channel Agonists; Cells, Cultured; Female; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase.
Topics: Acridines; Androstadienes; Animals; Basophils; Calcimycin; Calcium; Cell Adhesion; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Humans; Immunologic Capping; Integrin alpha4beta1; Integrins; Intracellular Signaling Peptides and Proteins; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Receptors, IgE; Receptors, Lymphocyte Homing; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases; Syk Kinase; Tetradecanoylphorbol Acetate; Transfection; Up-Regulation; Vascular Cell Adhesion Molecule-1; Wortmannin | 2001 |
Activation-induced mobilization of secretory vesicles in bovine neutrophils.
Topics: Alkaline Phosphatase; Animals; Cattle; Inflammation Mediators; Interleukin-8; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Platelet Activating Factor; Secretory Vesicles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Macrophage stimulating protein (MSP) evokes superoxide anion production by human macrophages of different origin.
Topics: Adult; Androstadienes; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Flavonoids; Growth Substances; Hepatocyte Growth Factor; Humans; Imidazoles; Insecta; Macrophages; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Proto-Oncogene Proteins; Pyridines; Receptors, Drug; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Effect of sarsasapogenin and its derivatives on the stimulus coupled responses of human neutrophils.
Topics: Arachidonic Acid; Cell Separation; Humans; In Vitro Techniques; Indicators and Reagents; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Tyrosine Phosphatases; Spirostans; Stereoisomerism; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Effect of six flavonoid compounds from Ixeris sonchifolia on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils.
Topics: Apigenin; Disaccharides; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glucosides; Glucuronides; Humans; Luteolin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Plants, Medicinal; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
[Luminescence analysis of respiratory burst in neutrophils using microtiter plates].
Topics: Calcimycin; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Degranulation of primary and secondary granules in adherent human neutrophils.
Topics: Acute-Phase Proteins; Carrier Proteins; Cell Adhesion; Cell Death; Cell Degranulation; Cell Survival; Extracellular Matrix Proteins; Humans; In Vitro Techniques; Lactoferrin; Lipocalin-2; Lipocalins; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oncogene Proteins; Peroxidase; Proto-Oncogene Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Prompt inhibition of fMLP-induced Ca2+ mobilization by parenteral lipid emulsions in human neutrophils.
Topics: Calcium; Calcium Signaling; Drug Combinations; Emulsions; Fat Emulsions, Intravenous; Fish Oils; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Olive Oil; Phospholipids; Plant Oils; Protein Kinase C; Sorbitol; Tetradecanoylphorbol Acetate | 2002 |
ARNO but not cytohesin-1 translocation is phosphatidylinositol 3-kinase-dependent in HL-60 cells.
Topics: ADP-Ribosylation Factor 1; Biological Transport; Cell Adhesion Molecules; Enzyme Activation; Fungal Proteins; Granulocytes; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Phospholipase D; Tetradecanoylphorbol Acetate | 2002 |
Differential regulation of neutrophil phospholipase d activity and degranulation.
Topics: Catechin; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phosphatidic Acids; Phospholipase D; Resveratrol; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate | 2002 |
[Modulation of the expression of L-selectin by chemotactic agents and GM-CSF].
Topics: Adolescent; Adult; Female; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Granulocytes; Humans; L-Selectin; Leukotriene B4; Lymphocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 2002 |
Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of (18)F-FDG PET images.
Topics: Deoxyglucose; Fluorodeoxyglucose F18; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Respiratory Burst; Tetradecanoylphorbol Acetate; Tomography, Emission-Computed; Tumor Necrosis Factor-alpha | 2002 |
Molecular and functional characterization of a new X-linked chronic granulomatous disease variant (X91+) case with a double missense mutation in the cytosolic gp91phox C-terminal tail.
Topics: Cell Membrane; Cytochrome b Group; Cytosol; Flavin-Adenine Dinucleotide; Granulomatous Disease, Chronic; Humans; Infant; Male; Membrane Glycoproteins; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neutrophils; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Tetradecanoylphorbol Acetate | 2002 |
Fenoterol inhibits superoxide anion generation by human polymorphonuclear leukocytes via beta-adrenoceptor-dependent and -independent mechanisms.
Topics: Adrenergic beta-Agonists; Albuterol; Dose-Response Relationship, Drug; Fenoterol; Free Radical Scavengers; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Procaterol; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
High magnesium concentration in vitro decreases human leukocyte activation.
Topics: Anions; Calcium; Eosinophils; Humans; In Vitro Techniques; Leukocytes; Leukotrienes; Magnesium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Oxygen; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Generation of reactive oxygen species by equine neutrophils and their effect on motility of equine spermatozoa.
Topics: Animals; Horses; Hydrogen Peroxide; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Sperm Motility; Tetradecanoylphorbol Acetate | 2002 |
Impaired neutrophil actin assembly causes persistent CD11b expression and reduced primary granule exocytosis in Type II diabetes.
Topics: Actins; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD11b Antigen; CD18 Antigens; Cytoplasmic Granules; Cytoskeleton; Diabetes Mellitus, Type 2; Exocytosis; Humans; Lectins, C-Type; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 2002 |
Effects of gold-chloroquine complexes on respiratory burst of polymorphonuclear leukocytes.
Topics: Adenosine Triphosphate; Cell Survival; Cell-Free System; Chloroquine; Dose-Response Relationship, Drug; Gold; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Effects of epoxyeicosatrienoic acids on polymorphonuclear leukocyte function.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Calcium; Cattle; Cell Adhesion; Cell Aggregation; Cells, Cultured; Chromium Radioisotopes; Endothelium, Vascular; Humans; In Vitro Techniques; Inflammation Mediators; Myocardial Reperfusion Injury; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Additive effects of Helicobacter pylori lipopolysaccharide and proteins in monocyte inflammatory responses.
Topics: Bacterial Proteins; CD11 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Helicobacter pylori; Humans; L-Selectin; Lipopolysaccharides; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Blockade of focal clustering and active conformation in beta 2-integrin-mediated adhesion of eosinophils to intercellular adhesion molecule-1 caused by transduction of HIV TAT-dominant negative Ras.
Topics: CD18 Antigens; Cell Adhesion; Chemokine CCL11; Chemokines, CC; Down-Regulation; Eosinophils; Gene Products, tat; Genes, ras; Humans; Intercellular Adhesion Molecule-1; Interleukin-5; Macrophage-1 Antigen; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Protein Conformation; ras Proteins; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transduction, Genetic | 2002 |
The effect of isoflurane on neutrophil selectin and beta(2)-integrin activation in vitro.
Topics: Adult; Anesthetics, Inhalation; Female; Flow Cytometry; Humans; In Vitro Techniques; Isoflurane; L-Selectin; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 2002 |
Nitrolinoleate inhibits superoxide generation, degranulation, and integrin expression by human neutrophils: novel antiinflammatory properties of nitric oxide-derived reactive species in vascular cells.
Topics: 1-Methyl-3-isobutylxanthine; Anti-Inflammatory Agents; Calcium; Cell Degranulation; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Integrins; Linoleic Acid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitro Compounds; Phosphodiesterase Inhibitors; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils.
Topics: Cell Fractionation; Centrifugation, Density Gradient; Cytoplasmic Granules; Eosinophil Peroxidase; Eosinophils; Gelatinases; Glycosylation; Humans; Ionomycin; Lactoferrin; Microscopy, Immunoelectron; N-Formylmethionine Leucyl-Phenylalanine; Peroxidase; Peroxidases; Protein Processing, Post-Translational; Salivary Proteins and Peptides; Seminal Plasma Proteins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Zymosan | 2002 |
Effect of five flavonoid compounds isolated from leaves of Diospyros kaki on stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Topics: Antihypertensive Agents; Blood Proteins; Diospyros; Dose-Response Relationship, Drug; Flavonoids; Hemolysis; Humans; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Plant Leaves; Plant Preparations; Plants, Medicinal; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Xenon preserves neutrophil and monocyte function in human whole blood.
Topics: Anesthetics, Inhalation; Blood Gas Analysis; Escherichia coli; Female; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; In Vitro Techniques; Male; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrous Oxide; Phagocytosis; Respiratory Burst; Tetradecanoylphorbol Acetate; Xenon | 2002 |
Recruitment of murine neutrophils in vivo through endogenous sialidase activity.
Topics: Animals; Blotting, Western; Bronchi; Calcimycin; Clostridium perfringens; Humans; Immunoglobulin G; Interleukin-8; Mice; Models, Animal; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate | 2003 |
Immunomodulatory effect of glutoxim on some activities of isolated human neutrophils and in whole blood.
Topics: Adjuvants, Immunologic; Adult; Animals; Cell Line; Dose-Response Relationship, Drug; Humans; Hypochlorous Acid; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Oligopeptides; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Effect of H1-antagonist Dithiaden on human PMN-leukocyte aggregation and chemiluminescence is stimulus-dependent.
Topics: Benzothiepins; Calcimycin; Cell Aggregation; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Ionophores; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 2002 |
Neutrophil activation and production of reactive oxygen species in pre-eclampsia.
Topics: Acridines; Adult; Case-Control Studies; Female; Humans; Indicators and Reagents; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2003 |
Antineutrophil cytoplasmic antibodies induce decreased CD62L expression and enhanced metabolic activity in monocytes.
Topics: Adolescent; Adult; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal; Biotransformation; CD11b Antigen; Fluorescent Antibody Technique; Humans; Hydrogen Peroxide; Immunoglobulin G; L-Selectin; Middle Aged; Monocytes; Myeloblastin; N-Formylmethionine Leucyl-Phenylalanine; Peroxidase; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 2003 |
Superoxide radical generation and Mn- and Cu-Zn superoxide dismutases activities in human leukemic cells.
Topics: Adult; Anions; Child; Humans; Imidazoles; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukocytes; Manganese; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Oxygen; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrazines; Sodium Dodecyl Sulfate; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Ceramide 1-phosphate formation in neutrophils.
Topics: Adult; Apoptosis; Blood Platelets; Calcium; Ceramides; Diglycerides; Enzyme Activation; Erythrocytes; Humans; Leukocytes, Mononuclear; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Tetradecanoylphorbol Acetate; Tritium | 2003 |
Effect of butylated hydroxyanisole and some of its derivatives on human neutrophil oxidative burst: chemiluminescence evaluation.
Topics: Adult; Antioxidants; Butylated Hydroxyanisole; Candida albicans; Cell-Free System; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indicators and Reagents; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phagocytosis; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
Novel and anti-inflammatory constituents of Garcinia subelliptica.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline O-Acetyltransferase; Cytochalasin B; Garcinia; In Vitro Techniques; Magnetic Resonance Spectroscopy; Mast Cells; Models, Molecular; Molecular Conformation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Superoxides; Tetradecanoylphorbol Acetate; Triterpenes | 2003 |
An intracellular modulation of free radical production could contribute to the beneficial effects of metformin towards oxidative stress.
Topics: Free Radicals; Gamma Rays; Humans; Hypoglycemic Agents; In Vitro Techniques; Leukocytes; Luminescent Measurements; Metformin; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate; Water | 2003 |
Characterization of Siglec-5 (CD170) expression and functional activity of anti-Siglec-5 antibodies on human phagocytes.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Communication; Cell Line; Humans; Lectins; Luminescent Measurements; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Hydrogen peroxide production by alveolar macrophages is increased and its concentration is elevated in the breath of rats exposed to hypoxia: relationship to lung lipid peroxidation.
Topics: Aldehydes; Analysis of Variance; Animals; Breath Tests; Data Interpretation, Statistical; Hydrogen Peroxide; Hypoxia; Lipid Peroxidation; Lung; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Wistar; Respiration; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Structure-function relationships of human C5a and C5aR.
Topics: Amino Acid Sequence; Antigens, CD; Binding, Competitive; Cell Migration Inhibition; Chemotaxis, Leukocyte; Complement C5a; Dose-Response Relationship, Immunologic; Humans; Hydrogen Peroxide; Iodine Radioisotopes; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Receptor, Anaphylatoxin C5a; Receptors, Complement; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2003 |
Respiratory burst activity of polymorphonuclear cells is dependent on the cell preparation technique.
Topics: Anesthetics, Intravenous; Blood Sedimentation; Chemotaxis, Leukocyte; Cytological Techniques; Escherichia coli; Ficoll; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Propofol; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arachidonic Acids; Basophils; Cells, Cultured; Complement C5a; Enzyme Inhibitors; Humans; Interleukin-3; Leukotriene C4; N-Formylmethionine Leucyl-Phenylalanine; Organophosphonates; Phospholipases A2; Platelet Activating Factor; Receptors, IgE; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2003 |
Histamine inhibits neutrophil NADPH oxidase activity triggered by the lipoxin A4 receptor-specific peptide agonist Trp-Lys-Tyr-Met-Val-Met.
Topics: Chemotactic Factors; Cytoplasmic Granules; Down-Regulation; Enzyme Inhibitors; Histamine; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oligopeptides; Receptors, Cell Surface; Receptors, Formyl Peptide; Receptors, Lipoxin; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Effect of three triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation and tyrosyl phosphorylation and translocation of p47(phox) and p67(phox) to cell membrane in human neutrophil.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Humans; Immunoblotting; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; Plant Roots; Protein Transport; Saponins; Superoxides; Tetradecanoylphorbol Acetate; Triterpenes; Tyrosine | 2003 |
Effects of a caffeine-free Cola nitida nuts extract on elastase/alpha-1-proteinase inhibitor balance.
Topics: alpha 1-Antitrypsin; Caffeine; Calcimycin; Cell Survival; Cola; Enzyme Activators; Free Radical Scavengers; Humans; Hydrogen Peroxide; In Vitro Techniques; Ionophores; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuts; Plant Extracts; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Protein phosphorylation in neutrophils monitored with phosphospecific antibodies.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antibodies; Binding Sites; Blood Proteins; Guinea Pigs; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Honokiol protects rat brain from focal cerebral ischemia-reperfusion injury by inhibiting neutrophil infiltration and reactive oxygen species production.
Topics: Animals; Biphenyl Compounds; Brain Ischemia; Calcium; Calcium Signaling; Cell Adhesion; Cerebral Infarction; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Infarction, Middle Cerebral Artery; Lignans; Lipid Peroxidation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neuroprotective Agents; Neutrophils; Rats; Rats, Long-Evans; Reactive Oxygen Species; Reperfusion Injury; Tetradecanoylphorbol Acetate | 2003 |
Relaxin inhibits the activation of human neutrophils: involvement of the nitric oxide pathway.
Topics: Calcium; Carcinogens; Chemotaxis, Leukocyte; Humans; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Relaxin; Superoxides; Tetradecanoylphorbol Acetate | 2004 |
The inducibility of TNF-alpha production is different in the granulocytic and monocytic differentiated forms of wild type and CGD-mutant PLB-985 cells.
Topics: Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Granulocytes; Granulomatous Disease, Chronic; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Monocytes; Mutation; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Cell Surface; Receptors, Complement 3b; Receptors, IgG; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2003 |
The effect of (1-->3)-beta-D-glucans, carboxymethylglucan and schizophyllan on human leukocytes in vitro.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; beta-Glucans; CD11b Antigen; Flow Cytometry; Glucans; Humans; Interleukin-6; Interleukin-8; L-Selectin; Leukocytes; Luminescent Measurements; Lymphocytes; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytes; Reactive Oxygen Species; Sizofiran; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Oxidative and adhesive responses of human neutrophils to nitrovasodilators in vitro: the role of protein kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Genistein; Humans; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Donors; Nitroprusside; Oxidation-Reduction; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2003 |
Dialyzer membrane type and reuse practice influence polymorphonuclear leukocyte function in hemodialysis patients.
Topics: Aged; Carcinogens; Cohort Studies; Comorbidity; Cross-Sectional Studies; Equipment Reuse; Female; Humans; Kidney Failure, Chronic; Male; Membranes, Artificial; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Renal Dialysis; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2004 |
Changes in neutrophil surface-receptor expression after stimulation with FMLP, endotoxin, interleukin-8 and activated complement compared to degranulation.
Topics: Anticoagulants; Carcinogens; Cell Degranulation; Complement Inactivator Proteins; Complement System Proteins; Elapid Venoms; Endotoxins; Flow Cytometry; Hirudins; Humans; Interleukin-8; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase; Receptors, Immunologic; Recombinant Proteins; Temperature; Tetradecanoylphorbol Acetate; Up-Regulation | 2004 |
Xenon modulates neutrophil adhesion molecule expression in vitro.
Topics: Anesthetics, Inhalation; CD18 Antigens; Cell Adhesion Molecules; Flow Cytometry; Humans; In Vitro Techniques; L-Selectin; Membrane Glycoproteins; Models, Biological; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Tetradecanoylphorbol Acetate; Xenon | 2004 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Inhibitory effect of furosemide on activation of human peripheral blood polymorphonuclear leukocytes stimulated with n-formyl-methionyl-leucyl-phenylalanine.
Topics: Calcium; Chemotaxis, Leukocyte; Cytosol; Diuretics; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Furosemide; Humans; In Vitro Techniques; Indicators and Reagents; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phagocytosis; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Thapsigargin | 2004 |
Interaction between leucocytes and human spermatozoa influencing reactive oxygen intermediates release.
Topics: Acridines; Humans; Indicators and Reagents; Leukocytes; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Reference Values; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate | 2004 |
Effects of hyperoxia on neutrophil adhesion.
Topics: Animals; CD18 Antigens; Cell Adhesion; Cyclic GMP; Endothelium, Vascular; Hyperbaric Oxygenation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Tetradecanoylphorbol Acetate | 2004 |
Polymorphonuclear leukocyte membrane fluidity and cytosolic Ca(2+) content in young adults with acute myocardial infarction. Evaluation at the initial stage and after 12 months.
Topics: Adult; Calcium; Cell Membrane; Cytosol; Fluorescent Dyes; Follow-Up Studies; Humans; Leukocyte Count; Male; Membrane Fluidity; Myocardial Infarction; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Mild hyperthermia down-regulates receptor-dependent neutrophil function.
Topics: Adult; CD11b Antigen; Cell Adhesion Molecules; Down-Regulation; Enzyme Activators; Fever; Humans; Hydrogen Peroxide; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Oxidative Stress; Phagocytosis; Protein Kinase C; Receptors, Leukocyte-Adhesion; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Characterization of six novel mutations in the CYBB gene leading to different sub-types of X-linked chronic granulomatous disease.
Topics: Genotype; Granulomatous Disease, Chronic; Humans; Immunoblotting; Male; Membrane Glycoproteins; Mutation; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Phenotype; Tetradecanoylphorbol Acetate | 2005 |
Polymorphonuclear leukocyte integrins in chronic renal failure.
Topics: Aged; CD11a Antigen; CD11b Antigen; CD11c Antigen; CD18 Antigens; Female; Humans; Integrins; Kidney Failure, Chronic; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate | 2005 |
Polymorphonuclear leukocyte integrins in deep venous thrombosis.
Topics: Female; Humans; Integrins; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Venous Thrombosis | 2005 |
Effect of cystic fibrosis exacerbations on neutrophil function.
Topics: Adult; Anti-Bacterial Agents; Cell Degranulation; Cystic Fibrosis; Female; Forced Expiratory Volume; Humans; Leukocyte Elastase; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Vital Capacity | 2005 |
Rapid non-genomic inhibitory effects of glucocorticoids on human neutrophil degranulation.
Topics: Cell Degranulation; Gene Expression Regulation; Genomics; Glucocorticoids; Humans; Hydrocortisone; Methylprednisolone; Mifepristone; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP.
Topics: Animals; Capillary Permeability; CD11b Antigen; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Humans; In Vitro Techniques; Lung; Lysophosphatidylcholines; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Oxidants; Phosphoproteins; Platelet Activating Factor; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Superoxides; Tetradecanoylphorbol Acetate; Up-Regulation | 2005 |
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
Topics: Animals; Butadienes; Calcium; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; Immunoblotting; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2005 |
Activation of oxidative burst and degranulation of porcine neutrophils by a homologous spleen galectin-1 compared to N-formyl-L-methionyl-L-leucyl-L-phenylalanine and phorbol 12-myristate 13-acetate.
Topics: Animals; Carbohydrate Sequence; Cell Degranulation; Galectin 1; Molecular Sequence Data; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Plant Preparations; Plant Proteins; Respiratory Burst; Ribosome Inactivating Proteins; Ribosome Inactivating Proteins, Type 2; Sequence Homology, Amino Acid; Spleen; Superoxides; Swine; Tetradecanoylphorbol Acetate; Toxins, Biological | 2005 |
Signal-specific activation and regulation of human neutrophil Fc gamma receptors.
Topics: Animals; Antigens, CD; CHO Cells; Complement C5a; Cricetinae; Dose-Response Relationship, Immunologic; Erythrocytes; Humans; Interleukin-8; K562 Cells; Kinetics; Ligands; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Protein Binding; Receptors, IgG; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 2005 |
Neutrophils activation can be diminished by apolipoprotein A-I.
Topics: Acute-Phase Reaction; Animals; Apolipoprotein A-I; Cell Adhesion; Cell Line; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Peroxidase; Rabbits; Reactive Oxygen Species; Receptors, Formyl Peptide; Tetradecanoylphorbol Acetate | 2005 |
Dapsone suppresses human neutrophil superoxide production and elastase release in a calcium-dependent manner.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cells, Cultured; Complement C5a; Dapsone; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2005 |
Cerebrospinal fluid and neutrophil respiratory burst after subarachnoid hemorrhage.
Topics: Adult; Aged; Cerebrospinal Fluid Proteins; Chemotaxis, Leukocyte; Female; Free Radicals; Humans; Immune Tolerance; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reference Values; Respiratory Burst; Subarachnoid Hemorrhage; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Differential role of an atypical protein kinase C, PKC zeta, in regulation of human eosinophil and neutrophil functions.
Topics: Cell Movement; Enzyme Inhibitors; Eosinophils; Humans; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 2005 |
Piecemeal degranulation of basophils and mast cells is effected by vesicular transport of stored secretory granule contents.
Topics: Animals; Basophils; Biological Transport; Cell Degranulation; Cytoplasmic Granules; Glycoproteins; Histamine; Humans; Lysophospholipase; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Transport Vesicles | 2005 |
Albumin attenuates neutrophil activation induced by stimulators including antibodies against neutrophil-specific antigens.
Topics: Antibodies, Monoclonal; Carcinogens; CD11b Antigen; Cells, Cultured; Granulocyte Colony-Stimulating Factor; Humans; L-Selectin; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Reactive Oxygen Species; Serum Albumin; Tetradecanoylphorbol Acetate | 2005 |
The inhibition of neutrophil-endothelial cell adhesion by hyaluronan independent of CD44.
Topics: Animals; Capillaries; Cell Adhesion; Cell Line; Cheek; Cricetinae; Dose-Response Relationship, Drug; E-Selectin; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Humans; Hyaluronan Receptors; Hyaluronic Acid; Intercellular Adhesion Molecule-1; Iodine Radioisotopes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Membrane; Cells, Cultured; Enzyme Activation; Mice; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neuropeptides; Neutrophils; Phospholipases A; Phospholipases A2; Phosphoproteins; Protein Kinase C-epsilon; Protein Transport; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RAC2 GTP-Binding Protein; Superoxides; Tetradecanoylphorbol Acetate | 2006 |
Hypertonic saline enhances neutrophil elastase release through activation of P2 and A3 receptors.
Topics: Adenosine Triphosphate; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Humans; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Purinergic P2; Saline Solution, Hypertonic; Tetradecanoylphorbol Acetate | 2006 |
Antioxidant potential of thymol determined by chemiluminescence inhibition in human neutrophils and cell-free systems.
Topics: Antioxidants; Arginine; Cell-Free System; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Peroxynitrous Acid; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Thymol | 2006 |
The inhibitory effect of phenylpropanoid glycosides and iridoid glucosides on free radical production and beta2 integrin expression in human leucocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Caffeic Acids; CD18 Antigens; Cells, Cultured; Free Radicals; Glucosides; Humans; Hydrazines; Iridoids; Leukocytes, Mononuclear; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phenols; Picrates; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2006 |
Effect of five triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation and translocation of p47(phox), p67(phox), and rac to cell membrane in human neutrophils.
Topics: Arachidonic Acid; Aralia; Cell Membrane; Cells, Cultured; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; rac GTP-Binding Proteins; Serine; Superoxides; Tetradecanoylphorbol Acetate; Threonine; Triterpenes; Tyrosine | 2006 |
Effect of the anti-anginal agent, perhexiline, on neutrophil, valvular and vascular superoxide formation.
Topics: Angina Pectoris; Animals; Animals, Newborn; Aorta, Thoracic; Aortic Valve; Cardiovascular Agents; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Free Radical Scavengers; Humans; In Vitro Techniques; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; NADP; NADPH Oxidases; Neutrophils; Perhexiline; Rats; Rats, Wistar; Superoxides; Swine; Tetradecanoylphorbol Acetate | 2006 |
Evaluation of in-vitro anti-inflammatory activity of some 2-alkyl-4,6-dimethoxy-1,3,5-triazines.
Topics: Anti-Inflammatory Agents; Cell Adhesion; Cells, Cultured; Endothelial Cells; Humans; Interleukin-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Triazines; Tumor Necrosis Factor-alpha | 2006 |
Acute inflammatory syndrome induced by mycophenolate mofetil in a patient following kidney transplantation.
Topics: Aged; Ankle Joint; Arthritis; Fever; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Syndrome; Tetradecanoylphorbol Acetate | 2006 |
Polymorphonuclear leukocyte dysfunction syndrome in patients with increasing sepsis severity.
Topics: C-Reactive Protein; Calcimycin; Calcitonin; CD18 Antigens; Humans; Hydrogen Peroxide; Interleukin-6; Leukocyte Count; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Opsonin Proteins; Phagocytosis; Protein Precursors; Sepsis; Severity of Illness Index; Shock, Septic; Syndrome; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2006 |
PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation.
Topics: Amino Acid Sequence; Androstadienes; Animals; Cells, Cultured; Enzyme Activation; Immunoglobulin G; Mice; Mice, Mutant Strains; Microspheres; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Peritoneum; Phosphatidylinositol Phosphates; Phosphoproteins; Protein Structure, Tertiary; Reactive Oxygen Species; Response Elements; Signal Transduction; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Wortmannin | 2006 |
Glycosyl-phosphatidyl-inositol-defective granulocytes from paroxysmal nocturnal haemoglobinuria patients show increased bacterial ingestion but reduced respiratory burst induction.
Topics: Adult; Animals; Carcinogens; Cells, Cultured; Enzyme Activation; Escherichia coli; Glycosylphosphatidylinositols; Granulocytes; Granulomatous Disease, Chronic; Hematopoiesis; Hemoglobinuria, Paroxysmal; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Phagocytosis; Protein Kinase C; Respiratory Burst; Tetradecanoylphorbol Acetate | 2007 |
Neutrophil dysfunction after biomaterial contact in an in vitro model of cardiopulmonary bypass.
Topics: Biocompatible Materials; Cardiopulmonary Bypass; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Gelatin; Humans; Models, Cardiovascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Polyvinyl Chloride; Surface Properties; Tetradecanoylphorbol Acetate | 2006 |
Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils.
Topics: Animals; Binding Sites; Blotting, Western; Cell Movement; Class I Phosphatidylinositol 3-Kinases; Complement C5a; Dose-Response Relationship, Drug; Female; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Proto-Oncogene Proteins c-akt; ras Proteins; Reactive Oxygen Species; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Kinetics of calcium ion concentration accompanying signal transduction in neutrophils from children with increased susceptibility to infections.
Topics: Adolescent; Calcium; Child; Child, Preschool; Female; Humans; Infant; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Tract Infections; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan | 2006 |
Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes.
Topics: Adult; Diabetes Mellitus; Female; Glucose; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hyperglycemia; Male; Middle Aged; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Nerve Growth Factors; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2007 |
Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Biphenyl Compounds; Cell Line; Ethanol; Evodia; Humans; Hydrazines; Indole Alkaloids; Mice; Microglia; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Picrates; Plant Extracts; Quinazolines; Reactive Oxygen Species; Synephrine; Tetradecanoylphorbol Acetate | 2007 |
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils.
Topics: Arginase; Cytoplasmic Granules; Exocytosis; Gelatinases; Granulocyte Precursor Cells; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.
Topics: Animals; Arachidonic Acids; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Granulocytes; Group IV Phospholipases A2; Humans; Indoles; Ion Channels; Maleimides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Okadaic Acid; Phospholipases A; Protein Kinase C; Protons; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Production of leukotriene C4 by peripheral blood leukocytes stimulated with anti-fcepsilonRI antibody, PMA, and fMLP does not correlate with irreversible airway obstruction in asthmatics.
Topics: Adult; Airway Obstruction; Antibodies; Asthma; Cells, Cultured; Humans; Leukocytes; Leukotriene C4; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Receptors, IgE; Spirometry; Tetradecanoylphorbol Acetate | 2007 |
Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity.
Topics: Animals; Blood Bactericidal Activity; Calcium; Chlorides; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Humans; Immunity, Innate; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Patch-Clamp Techniques; Peptides; Potassium Channel Blockers; Reactive Oxygen Species; Respiratory Burst; Staphylococcal Infections; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Yersinia enterocolitica; Yersinia Infections; Zinc Compounds | 2007 |
Distinct involvement of p38-, ERK1/2 and PKC signaling pathways in C5a-mediated priming of oxidative burst in phagocytic cells.
Topics: Complement C5a; Enzyme Inhibitors; Escherichia coli; Extracellular Signal-Regulated MAP Kinases; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phagocytes; Protein Kinase C; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Oxygen radical production and severity of the Guillain--Barré syndrome.
Topics: Adult; Aged; Aged, 80 and over; Female; Guillain-Barre Syndrome; Humans; Leukocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Oligopeptides; Reactive Oxygen Species; Severity of Illness Index; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis.
Topics: Amino Acid Substitution; Animals; Antigen-Antibody Complex; Carcinogens; Cell Line; Guanine Nucleotide Dissociation Inhibitors; Humans; Lim Kinases; Membrane Glycoproteins; Mice; Microglia; Mutation, Missense; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidase 2; NADPH Oxidases; Neuropeptides; p21-Activated Kinases; Phagocytes; Proto-Oncogene Proteins c-vav; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Receptors, IgG; Respiratory Burst; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 2008 |
Flow-cytometric measurement of respiratory burst in rat polymorphonuclear granulocytes: Comparison of four cell preparation procedures, and concentration-response evaluation of soluble stimulants.
Topics: Animals; Cell Separation; Flow Cytometry; Granulocytes; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Rats, Wistar; Respiratory Burst; Solubility; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2008 |
Anti-inflammatory effects of dimemorfan on inflammatory cells and LPS-induced endotoxin shock in mice.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Calcium; Cytokines; Fluorescent Antibody Technique; Humans; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Macrophage-1 Antigen; Mice; Morphinans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Shock, Septic; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Up-Regulation | 2008 |
A pH-stabilizing role of voltage-gated proton channels in IgE-mediated activation of human basophils.
Topics: Antibodies, Anti-Idiotypic; Basophils; Benzopyrans; Electrophysiology; Histamine; Humans; Hydrogen-Ion Concentration; Hypersensitivity; Immunoglobulin E; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Proton Pump Inhibitors; Proton Pumps; Tetradecanoylphorbol Acetate; Zinc | 2008 |
Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in rats.
Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Benzofurans; Depsides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Hyperuricemia; Inflammation; Male; Molecular Conformation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxonic Acid; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Uric Acid; Xanthine Oxidase | 2008 |
Tamoxifen does not inhibit the swell activated chloride channel in human neutrophils during the respiratory burst.
Topics: Cells, Cultured; Chloride Channels; Colforsin; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phloretin; Respiratory Burst; Superoxides; Tamoxifen; Tetradecanoylphorbol Acetate; Trialkyltin Compounds | 2008 |
Oxidative burst assessment and neutrophil-platelet complexes in unlysed whole blood.
Topics: Anthraquinones; Antibodies, Monoclonal; Blood Platelets; Calcimycin; Carcinogens; Flow Cytometry; Humans; Ionophores; Leukocyte Common Antigens; Lipopolysaccharide Receptors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Rhodamines; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Zymosan | 2008 |
Effect of glycine on the release of reactive oxygen species in human neutrophils.
Topics: Calcium Signaling; Cell Separation; Extracellular Space; Glycine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Strychnine; Tetradecanoylphorbol Acetate | 2009 |
Inhibition of superoxide generation and myeloperoxidase release by carvedilol after receptor and nonreceptor stimulation of human neutrophils.
Topics: Adrenergic beta-Antagonists; Androstadienes; Calcimycin; Carbazoles; Carvedilol; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Peroxidase; Phosphatidylinositol 3-Kinases; Propanolamines; Protein Kinase C; Receptors, Adrenergic, beta; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 2008 |
Effects of short chain fatty acids on effector mechanisms of neutrophils.
Topics: Animals; Bacteria; Candida albicans; Carcinogens; Fatty Acids, Volatile; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phagocytosis; Rats; Rats, Wistar; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2009 |
Activation of equine neutrophils by phorbol myristate acetate or N-formyl-methionyl-leucyl-phenylalanine induces a different response in reactive oxygen species production and release of active myeloperoxidase.
Topics: Animals; Biphenyl Compounds; Cell Degranulation; Cytochalasin B; Ethylenes; Horse Diseases; Horses; In Vitro Techniques; Inflammation; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Onium Compounds; Peroxidase; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2009 |
Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose.
Topics: Abscisic Acid; ADP-ribosyl Cyclase 1; Amyloid beta-Peptides; Animals; Binding Sites; Calcium; Cell Line; Chemokines; Chemotaxis; Cyclic ADP-Ribose; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Lipopolysaccharides; Mice; Microglia; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; N-Glycosyl Hydrolases; Nitric Oxide; Phosphorylation; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Relationship between calcium release and NADPH oxidase inhibition in human neutrophils.
Topics: Calcium; Cells, Cultured; Fatty Alcohols; Glycols; Humans; Leukotriene Antagonists; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate; Tetrazoles | 2009 |
Respiratory burst function of ovine neutrophils.
Topics: Animals; Immunity, Innate; Immunologic Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Reactive Oxygen Species; Respiratory Burst; Sheep; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Myristoylated alanine-rich C-kinase substrate (MARCKS) protein regulation of human neutrophil migration.
Topics: Actins; CD18 Antigens; Cell Adhesion; Cell Membrane; Cell Polarity; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptides; Tetradecanoylphorbol Acetate | 2010 |
In vitro inhibitory effect of apple peel extract on the growth of Helicobacter pylori and respiratory burst induced on human neutrophils.
Topics: Adenosine Triphosphate; Flavonoids; Fruit; Helicobacter pylori; Humans; Malus; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Respiratory Burst; Tetradecanoylphorbol Acetate | 2009 |
Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP.
Topics: Animals; Carcinogens; CHO Cells; Cricetinae; Cricetulus; Exocytosis; Ficolins; Gene Expression Regulation; Humans; Lectins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Secretory Vesicles; Tetradecanoylphorbol Acetate | 2009 |
Outside-in signal transmission by conformational changes in integrin Mac-1.
Topics: Antibodies, Monoclonal; Apoptosis; Carcinogens; Cell Adhesion; Cell Line, Tumor; Humans; Immunologic Factors; Intercellular Adhesion Molecule-1; Interleukin-8; Leukemia; Leukocytes, Mononuclear; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Structure, Tertiary; Signal Transduction; Tetradecanoylphorbol Acetate | 2009 |
No relationship between neutrophil granulocyte activation and the myeloperoxidase gene - 129 G>A and - 463 G>A promoter polymorphisms: implications for investigations of cardiovascular disease.
Topics: Cardiovascular Diseases; Cell Degranulation; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase; Phenotype; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Reactive Oxygen Species; Risk Assessment; Risk Factors; Tetradecanoylphorbol Acetate | 2009 |
Persistency and pathway of isoflurane-induced inhibition of superoxide production by neutrophils.
Topics: Anesthetics, Inhalation; Animals; Calcimycin; Dogs; Isoflurane; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst.
Topics: 1-Butanol; Calcium; Cells, Cultured; Diglycerides; Enzyme Inhibitors; Estrenes; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphodiesterase Inhibitors; Phospholipase D; Protein Kinase C; Protein Transport; Pyrrolidinones; Respiratory Burst; Tetradecanoylphorbol Acetate | 2011 |
Extracellular signal-regulated kinase (ERK) activation in chicken heterophils stimulated with phorbol 12-myristate 13-acetate (PMA), formyl-methionylleucyl-phenylalanine (fMLP) and lipopolysaccharide (LPS).
Topics: Animals; Calcium; Chickens; Extracellular Signal-Regulated MAP Kinases; Extracellular Space; Intracellular Space; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2009 |
Dinucleoside polyphosphates: newly detected uraemic compounds with an impact on leucocyte oxidative burst.
Topics: Chronic Disease; Dinucleoside Phosphates; Humans; Kidney Diseases; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Uremia | 2010 |
Anti-alpha4beta1 integrin antibody induces receptor internalization and does not impair the function of circulating neutrophilic leukocytes.
Topics: Animals; Antibodies, Monoclonal; Chemotaxis, Leukocyte; Female; Integrin alpha4beta1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Rats; Rats, Wistar; Reactive Oxygen Species; Spinal Cord Injuries; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Inhibition of neutrophil-mediated production of reactive oxygen species (ROS) by endothelial cells is not impaired in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis patients.
Topics: Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Cell Communication; Cell Degranulation; Cells, Cultured; Coculture Techniques; Endothelial Cells; Humans; Interleukin-8; Leukocytes, Mononuclear; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Complement alternative pathway acts as a positive feedback amplification of neutrophil activation.
Topics: Blood; Cells, Cultured; Complement Activation; Complement C3; Complement C5; Complement Pathway, Alternative; Feedback, Physiological; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Evaluation of TLR4 expression and chosen parameters of oxidative-antioxidative balance in young children with food allergy.
Topics: Antioxidants; Case-Control Studies; Child, Preschool; Food Hypersensitivity; Humans; Hypersensitivity, Immediate; Immunity, Innate; Infant; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; RNA, Messenger; Tetradecanoylphorbol Acetate; Toll-Like Receptor 4; Zymosan | 2010 |
Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection.
Topics: Aged; Aged, 80 and over; Animals; Arachidonate 5-Lipoxygenase; Bacterial Infections; Eicosanoids; Female; Gram-Positive Bacterial Infections; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-8; Male; Mice; Mice, Inbred C57BL; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritonitis; Phospholipids; Plasmalogens; Signal Transduction; Staphylococcal Infections; Staphylococcus epidermidis; Superoxides; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate | 2011 |
Inhibitory effects of secoiridoids from the roots of Gentiana straminea on stimulus-induced superoxide generation, phosphorylation and translocation of cytosolic compounds to plasma membrane in human neutrophils.
Topics: Arachidonic Acid; Cell Membrane; Cells, Cultured; Gentiana; Humans; Iridoid Glucosides; Iridoids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Plant Roots; Protein Transport; Pyrones; Superoxides; Tetradecanoylphorbol Acetate | 2012 |
Sulfhydryl modification induces calcium entry through IP₃-sensitive store-operated pathway in activation-dependent human neutrophils.
Topics: Adult; Animals; Boron Compounds; Calcium; Calcium Signaling; Cell Movement; Estrenes; Ethylmaleimide; Humans; Inositol 1,4,5-Trisphosphate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Nitroprusside; Pyrrolidinones; Rats; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Thapsigargin | 2011 |
Oxidative and nitrative modifications of enkephalins by human neutrophils: effect of nitroenkephalin on leukocyte functional responses.
Topics: Analysis of Variance; Apoptosis; Cells, Cultured; Enkephalin, Leucine; Enzyme Activators; Humans; Hydrazines; Inflammation Mediators; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide Donors; Oxidation-Reduction; Reactive Nitrogen Species; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 2012 |
Effects of extracellular lactate on production of reactive oxygen species by equine polymorphonuclear leukocytes in vitro.
Topics: Animals; Cell Survival; Female; Horses; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Lactic Acid; Luminescence; Male; Monocarboxylic Acid Transporters; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Physical Conditioning, Animal; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Zymosan | 2012 |
Manganese promotes increased formation of hydrogen peroxide by activated human macrophages and neutrophils in vitro.
Topics: Air Pollutants, Occupational; Catalysis; Cells, Cultured; Chlorides; Free Radical Scavengers; Humans; Hydrogen Peroxide; Macrophage Activation; Macrophages; Manganese; Manganese Compounds; Manganese Poisoning; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Occupational Exposure; Osmolar Concentration; Oxidants; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2012 |
The influence of uremic high cystatin C concentration on neutrophil apoptosis and selected neutrophil functions isolated from healthy subjects.
Topics: Adult; Apoptosis; Caspase 3; Cell Respiration; Cell Separation; Cells, Cultured; Cystatin C; Fas Ligand Protein; Female; Health; Humans; Interleukin-1beta; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uremia | 2012 |
Modulation of immune functions in polymorphonuclear neutrophils induced by physostigmine, but not neostigmine, independent of cholinergic neurons.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Cholinergic Neurons; Cholinesterase Inhibitors; Humans; L-Selectin; Macrophage-1 Antigen; Male; N-Formylmethionine Leucyl-Phenylalanine; Neostigmine; Neutrophils; Physostigmine; Rats; Rats, Wistar; Respiratory Burst; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
The effect of bisphosphonate therapy on neutrophil function: a potential biomarker.
Topics: Aged; Aged, 80 and over; Biomarkers; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Chemotaxis; Diphosphonates; Disease Susceptibility; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Mouth Mucosa; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osteoradionecrosis; Pamidronate; Phagocytosis; Reactive Oxygen Species; Respiratory Burst; Saliva; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2013 |
Protectin DX, a double lipoxygenase product of DHA, inhibits both ROS production in human neutrophils and cyclooxygenase activities.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Humans; Immunoblotting; Isomerism; Lipopolysaccharides; Lipoxygenase; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Peroxidase; Phosphorylation; Prostaglandins; Reactive Oxygen Species; Serine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2014 |
The essential oil of bergamot stimulates reactive oxygen species production in human polymorphonuclear leukocytes.
Topics: Calcium; Citrus; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oils, Volatile; Plant Oils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2014 |
B-Type natriuretic peptide suppression of neutrophil superoxide generation: mechanistic studies in normal subjects.
Topics: Carbazoles; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Humans; N-Formylmethionine Leucyl-Phenylalanine; Natriuretic Peptide, Brain; Neutrophils; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 2014 |
Dual stimulus-dependent effect of Oenothera paradoxa extract on the respiratory burst in human leukocytes: suppressing for Escherichia coli and phorbol myristate acetate and stimulating for formyl-methionyl-leucyl-phenylalanine.
Topics: Chromatography, High Pressure Liquid; Drug Synergism; Escherichia coli; Humans; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Oenothera; Plant Extracts; Polyphenols; Reactive Oxygen Species; Respiratory Burst; Seeds; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate | 2014 |
Neutrophil functions in morbidly obese subjects.
Topics: Adult; Body Mass Index; CD11b Antigen; Cell Adhesion; Cell Movement; Female; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Obesity, Morbid; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2015 |
The Noninflammatory Phenotype of Neutrophils From the Closed-Eye Environment: A Flow Cytometry Analysis of Receptor Expression.
Topics: Adult; Antigens, CD; Cell Adhesion Molecules; Female; Flow Cytometry; GPI-Linked Proteins; Humans; Intercellular Adhesion Molecule-1; Leukocyte Common Antigens; Leukocyte Count; Lipopolysaccharides; Macrophage-1 Antigen; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phenotype; Reactive Oxygen Species; Receptors, Complement; Sleep; Tears; Tetradecanoylphorbol Acetate; Young Adult | 2015 |
CFTR targeting during activation of human neutrophils.
Topics: Adult; Antibodies, Monoclonal; Antibody Specificity; Cell Membrane; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exocytosis; Female; Flow Cytometry; Gene Expression Regulation; Humans; Hypochlorous Acid; Lipopolysaccharides; Male; Microspheres; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Opsonin Proteins; Phagosomes; Point Mutation; Protein Domains; Protein Transport; Receptors, Formyl Peptide; Tetradecanoylphorbol Acetate | 2016 |
Impaired Blood Neutrophil Function in the Frequent Exacerbator of Chronic Obstructive Pulmonary Disease: A Proof-of-Concept Study.
Topics: Aged; Case-Control Studies; Cell Degranulation; Disease Progression; Female; Humans; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proof of Concept Study; Pulmonary Disease, Chronic Obstructive; Respiratory Burst; Symptom Flare Up; Tetradecanoylphorbol Acetate | 2016 |
Bacterial N-formyl Peptides Reduce PMA- and Escherichia coli-Induced Neutrophil Respiratory Burst in Term Neonates and Adults.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Escherichia coli; Flow Cytometry; Humans; Infant, Newborn; Interleukin-8; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Young Adult | 2017 |
Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Cathepsin G; Cell Adhesion; Cell Movement; Cells, Cultured; Cytochalasin D; Fibronectins; Humans; Lipopolysaccharides; Matrix Metalloproteinase 9; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thiazolidines | 2017 |
CD40 ligand deficiency causes functional defects of peripheral neutrophils that are improved by exogenous IFN-γ.
Topics: Animals; CD40 Ligand; Female; HL-60 Cells; Humans; Hyper-IgM Immunodeficiency Syndrome, Type 1; Interferon-gamma; Mice, Inbred C57BL; Mice, Knockout; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Paracoccidioides; Reactive Oxygen Species; Recombinant Proteins; Respiratory Burst; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Transcriptome | 2018 |
Detection of activated neutrophils by reactive oxygen species production using a hematology analyzer.
Topics: Female; Flow Cytometry; Humans; Male; Microscopy, Confocal; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2018 |
Imaging and Quantification of Secreted Peroxynitrite at the Cell Surface by a Streptavidin-Biotin-Controlled Binding Probe.
Topics: Animals; Biotin; Carbocyanines; Cell Membrane; Enzyme Activators; Fluorescent Dyes; Gene Expression; Interferon-gamma; Lipopolysaccharides; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Phosphatidylinositol 4,5-Diphosphate; RAW 264.7 Cells; Streptavidin; Tetradecanoylphorbol Acetate | 2018 |
Imidazole alkaloids inhibit the pro-inflammatory mechanisms of human neutrophil and exhibit anti-inflammatory properties in vivo.
Topics: 4-Butyrolactone; Alkaloids; Animals; Anti-Inflammatory Agents; Calcium; Humans; Hyperalgesia; Imidazoles; Interleukin-6; Male; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; NF-kappa B; Peroxidase; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2019 |
Neutrophil Functions in Immunodeficiency Due to DOCK8 Deficiency.
Topics: Adolescent; Cells, Cultured; Chemotaxis; Child; Child, Preschool; Codon, Nonsense; Guanine Nucleotide Exchange Factors; Humans; Immunologic Deficiency Syndromes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate | 2019 |
Polymorphonuclear Cell Chemotaxis and Suicidal NETosis: Simultaneous Observation Using fMLP, PMA, H7, and Live Cell Imaging.
Topics: Chemotaxis, Leukocyte; Extracellular Traps; Humans; Molecular Imaging; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Time-Lapse Imaging | 2020 |
Dynamic Changes in the Ability to Release Neutrophil ExtraCellular Traps in the Course of Childhood Acute Leukemias.
Topics: Acute Disease; Adolescent; Calcium Ionophores; Cells, Cultured; Child; Child, Preschool; Extracellular Traps; Humans; Immunity, Innate; Infant; Leukemia; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 2021 |
Non-invasive and accurate readout of superoxide anion in biological systems by near-infrared light.
Topics: Animals; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Peroxidase; Superoxides; Tetradecanoylphorbol Acetate | 2021 |
The Differential Reactive Oxygen Species Production of Tear Neutrophils in Response to Various Stimuli In Vitro.
Topics: Adult; Carcinogens; Female; Humans; Lipopolysaccharides; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Reactive Oxygen Species; Tears; Tetradecanoylphorbol Acetate; Young Adult | 2021 |