tetradecanoylphorbol acetate has been researched along with mezerein in 186 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (59.14) | 18.7374 |
| 1990's | 69 (37.10) | 18.2507 |
| 2000's | 4 (2.15) | 29.6817 |
| 2010's | 2 (1.08) | 24.3611 |
| 2020's | 1 (0.54) | 2.80 |
| Authors | Studies |
|---|---|
| Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
| Diamond, L; O'Brien, TG; Rovera, G | 1 |
| Kensler, TW; Mueller, GC | 1 |
| Davis, BB; Jacob, AK; Reznikoff, CA; Thomas, DJ; Zenser, TV | 1 |
| Ji, C; Marnett, LJ | 1 |
| Estabrook, A; Fisher, PB; Gutierrez, MC; Jiang, H; Leon, JA; Waxman, S | 1 |
| Friesel, RE; Peifley, KA; Winkles, JA | 1 |
| Bennett, MV; Durand, GM; Gregor, P; Uhl, GR; Zheng, X; Zukin, RS | 1 |
| Hii, CS; Isaac, EL; Murray, AW | 1 |
| Anderson, GM; Horne, WC | 1 |
| Baker, RS; Bonin, AM; Meher-Homji, K; Steinel, HH | 1 |
| Morahan, PS; Tenney, DJ | 1 |
| Duffy, PA; Garner, RC; Hewitt, SD; Orton, TC | 1 |
| Altmeyer, A; Dijkmans, R; Dumont, FJ; Fischer, PA; Palfree, RG; Staruch, MJ | 1 |
| Grinstein, S; Nanda, A | 1 |
| Alberola-Ila, J; Lozano, F; Places, L; Vives, J | 1 |
| Gilmour, SK; Megosh, L; Mitchell, J; O'Brien, TG; O'Connell, SM; Robertson, FM | 1 |
| Gross, JL; Mochan, E; Newton, RC; Rommi, W; Uhl, J | 1 |
| Logun, C; Lundgren, JD; Rieves, RD; Shelhamer, JH; Wu, T | 1 |
| Turla, MB; Webb, RC | 2 |
| Singh, N | 2 |
| Akasu, M; Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Harmody, D; Longley, RE | 1 |
| Jordan, ML; Wright, J | 1 |
| McMurtry, IF; Orton, EC; Raffestin, B | 1 |
| Bhisey, RA; Veturkar, PL | 1 |
| Hennings, H; Jung, R; Michael, DM; Pettit, GR; Robinson, VA; Yuspa, SH | 1 |
| Burger, HG; Farnworth, PG; Findlay, JK; Wang, QF | 3 |
| Ewanowich, CA; Peppler, MS | 1 |
| Cioffi, CL; Fisher, SK | 1 |
| Park, SM; Turla, MB; Webb, RC | 1 |
| Chedrese, PJ; Juorio, AV; Labrie, F; Luu The, V; Murphy, BD; Zhang, D | 1 |
| Pitt, BR; Weng, W | 1 |
| Paulsen, JE | 1 |
| Chacko, KV; Hise, MK | 1 |
| Crowcroft, NS; Parkinson, EK; Quigley, JP; Stanley, MA | 1 |
| Hennings, H; Mitchell, P; Shores, R; Spangler, EF; Yuspa, SH | 1 |
| Park, S; Rasmussen, H | 1 |
| Chaffin, KE; Gentry, LE; Purchio, AF; Shoyab, M | 1 |
| Belitsky, GA; Budunova, IV; Mittelman, LA | 1 |
| Conti, CJ; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Blumberg, PM; Hennings, H; Sharkey, NA; Yuspa, SH | 1 |
| Czerniecki, BJ; Witz, G | 1 |
| Badwey, JA; Curnutte, JT; Heyworth, PG; Robinson, JM | 1 |
| Arlinghaus, RB; Kabat, KG; Kloetzer, WS; Li, WJ; Smith, LA | 1 |
| Arkhammar, P; Berggren, PO; Nilsson, T; Welsh, M; Welsh, N | 1 |
| Lamkin, GE; Lane, TA; Wancewicz, E | 1 |
| Conney, AH; Hansen, LA; Mills, KJ; Smart, RC | 1 |
| Blumberg, PM; Szallasi, A | 1 |
| Andringa, A; Baxter, CS; Chalfin, K; Miller, ML | 2 |
| Barton, K; Randall, G; Sagone, AL | 1 |
| Gascard, P; Giraud, F; Sulpice, JC | 1 |
| Stich, HF; Tsang, SS | 1 |
| Honegger, P | 1 |
| Emoto, N; Obuchi, E; Ohmura, E; Shizume, K; Tsushima, T | 1 |
| Dale, IL; Gescher, A | 1 |
| Aitken, A; Brooks, G; Evans, AT; Evans, FJ | 1 |
| Inui, N; Iwata, K; Ohkawa, Y; Shibuya, H | 1 |
| Kanno, Y | 1 |
| Chida, K; Kuroki, T; Munakata, K; Murakami, Y | 1 |
| Czerniecki, B; Gad, SC; Reilly, C; Smith, AC; Witz, G | 1 |
| Jacobson, DP; O'Flaherty, JT; Redman, JF | 1 |
| Kanno, Y; Sasaki, Y; Sastrodihardjo, S; Shiba, Y | 1 |
| Blumberg, PM; Bressler, JP; Frost, MM; Leach, KL | 1 |
| Ariño, J; Guinovart, JJ | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB; Simsiman, RC | 1 |
| Baxter, CS; Carson, DL | 1 |
| Chambaz, EM; Cochet, C; Keramidas, M; Souvignet, C | 1 |
| Le, JM; Vilcek, J; Yip, YK | 1 |
| Croll, AD; Morris, AG; Pither, JM; Siggins, KW | 1 |
| Kreutter, D; Morin, MJ; Rasmussen, H; Sartorelli, AC | 1 |
| DiGiovanni, J; Naito, M; Naito, Y | 1 |
| Belitskiĭ, GA; Budunova, IV; Mittel'man, LA | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Crysup, SE; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Czerniecki, B; Gad, SC; Reilly, C; Witz, G | 1 |
| Aizu, E; Gotoh, H; Hiai, H; Kato, R; Sasakawa, N; Yamamoto, S | 1 |
| Bass, D; Cousart, S; McCall, C; O'Flaherty, J; Schmitt, J; Wykle, R | 1 |
| Albert, PR; Tashjian, AH | 1 |
| Deli, E; Kiss, Z; Kuo, JF | 1 |
| Andringa, A; Baxter, CS; Miller, ML | 1 |
| Bhisey, RA; Borges, A; Jeyapaul, J; Veturkar, PL | 1 |
| Del Buono, BJ; Schlegel, RA; Williamson, PL | 1 |
| Bhisey, RA; Borges, AM; Notani, PN; Ramchandani, AG; Sirsat, SM; Veturkar, PL | 1 |
| Iwashima, A; Lijian, Y; Nishino, H | 1 |
| Deli, E; Kiss, Z; Koeffler, HP; Kuo, JF; Pettit, GR; Shoji, M; Vogler, WR | 1 |
| Adams, LM; Conti, CJ; Fischer, SM; Fries, JW; O'Connell, JF; Patrick, KE; Slaga, TJ; Tacker, KC | 1 |
| Baxter, CS; Miller, ML | 1 |
| Abernethy, DJ; Boreiko, CJ; Dorman, BH; Sanchez, JH | 1 |
| Du Pasquier, P; Honegger, P; Tenot, M | 1 |
| Cooke, E; Hallett, MB; Horgan, K; Mansel, RE | 1 |
| Chrzan, K; Frenkel, K | 1 |
| Clark, DA; Dessypris, EN; Koury, MJ | 1 |
| Degen, JL; Estensen, RD; Nagamine, Y; Reich, E | 1 |
| Goodsel, D; Granger, GA; Klostergaard, J | 1 |
| Argyris, TS | 2 |
| Fürstenberger, G; Kinzel, V; Marks, F; Schwarz, M | 1 |
| McCall, CE; O'Flaherty, JT; Redman, JF; Schmitt, JD; Wykle, RL | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB | 1 |
| Castagna, M; Hanania, N; Harel, J; Shaool, D; Zeliszewski, D | 1 |
| Morris, A; Siggens, KW; Tinsley, JM | 1 |
| Boutwell, RK; Simsiman, RC; Takigawa, M | 1 |
| Takahashi, K; Takenaga, K | 1 |
| Chang, CC; Kavanagh, TJ; Trosko, JE | 1 |
| Cooke, E; Hallett, MB | 1 |
| Klein-Szanto, AJ; Major, SK; Slaga, TJ | 2 |
| Engelhardt, DL; Laskin, JD; Mufson, RA; Piccinini, L; Weinstein, IB | 1 |
| Emmerson, A; Parkinson, EK | 1 |
| Reiners, JJ; Slaga, TJ | 1 |
| Enomoto, T; Kanno, Y; Martel, N; Shiba, Y; Yamasaki, H | 1 |
| Emmerson, A; Gorman, PA; Parkinson, EK; Pera, MF | 1 |
| Kaibuchi, K; Kikkawa, U; Miyake, R; Nishizuka, Y; Tanaka, Y; Tsuda, T | 1 |
| Amoruso, M; Goldstein, BD; Stone, DS; Troll, W; Witz, G | 1 |
| Goldstein, B; Stone, D; Sugimura, T; Troll, W; Witz, G | 1 |
| Sachs, L; Simantov, R | 1 |
| Eisinger, M; Marko, O; Weinstein, IB | 1 |
| Oettgen, HF; Palladino, MA; Pearlstein, KT; Stone-Wolff, DS; Vilcek, J | 1 |
| Fey, EG; Penman, S | 1 |
| Chou, TC; Kopelovich, L | 1 |
| Martel, N; Yamasaki, H | 1 |
| Kalimi, GH; Sirsat, SM | 2 |
| Chida, K; Kuroki, T | 1 |
| Blumberg, PM; Jaken, S; Shupnik, MA; Tashjian, AH | 1 |
| Colburn, NH; Srinivas, L | 1 |
| Fujiki, H; Hayashi, K; Sugimura, T | 1 |
| Fischer, SM; Klein-Szanto, AJ; Major, S; Nelson, K; Slaga, TJ; Weeks, CE | 1 |
| Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ | 1 |
| Herrmann, AL; Nelson, FR; Slaga, TJ; Weeks, CE | 1 |
| Davidson, KA; Slaga, TJ | 2 |
| Astrup, EG; Paulsen, JE | 1 |
| Fischer, SM; Klein-Szanto, AJ; Mamrack, M; Nelson, K; Slaga, TJ; Weeks, CE | 1 |
| Boutwell, RK; O'Leary, P; Perrella, FW | 1 |
| Guy, GR; Murray, AW | 1 |
| Fitzgerald, DJ; Guy, GR; Murray, AW | 1 |
| Shiba, Y | 1 |
| Logani, MK; Slaga, TJ; Solanki, V | 1 |
| Choi, B; Chun, JS; Kang, SS; Lee, YS; Sonn, JK | 1 |
| Thurston, G; Turner, D | 1 |
| Amon, U; Ramachers, U; von Stebut, E; Wolff, HH | 1 |
| Benford, DJ; Lawrence, JN | 1 |
| Hansen, H; Riedel, H; Shieh, HL; Zhu, J | 2 |
| Anderson, J; Barnett, T; Birt, DF; Pelling, JC | 1 |
| Antony, M; Gupta, KP; Mehrotra, NK; Shukla, Y | 1 |
| Brandsch, M; Ganapathy, V; Leibach, FH; Miyamoto, Y | 1 |
| Corrèze, C; Delemer, B; Dib, K; el Jamali, A; Haye, B; Jacquemin, C | 1 |
| Agarwal, R; Katiyar, SK; Mukhtar, H | 1 |
| Kelly, PA; Lee, CS; Ormandy, CJ; Sutherland, RL | 1 |
| Bencherif, M; Lukas, RJ | 1 |
| Detimary, P; Gao, ZY; Gembal, M; Gilon, P; Henquin, JC | 1 |
| Cines, DB; Schmaier, AH; Zini, JM | 1 |
| Belanger, AJ; Glick, AB; Hennings, H; Tennenbaum, T; Weiner, AK; Yuspa, SH | 1 |
| Aldaz, CM; Conti, CJ; DiGiovanni, J; Slaga, TJ; Walker, SE | 1 |
| McCann, R; Mitchel, RE | 1 |
| Frenkel, K; Wei, H | 1 |
| Davis, AW; Gao, XM; Hua, DH; Newell, SW; Perchellet, EM; Perchellet, JP | 1 |
| Kizawa, Y; Kusama, T; Murakami, H; Sakurai, M; Uhl, GR | 1 |
| Chen, LC; De Luca, LM; Huynh, M; Jones, CS; Tarone, R | 1 |
| Fahrig, R; Steinkamp-Zucht, A | 1 |
| Agarwal, R; Ahmad, N; Mohan, RR; Mukhtar, H | 1 |
| Akiyama, H; Aoki, H; Hosoya, H; Marunouchi, T; Morioku, T; Souda, M | 1 |
| Brüne, B; Messmer, UK | 1 |
| Honegger, P; Lassmann, H; Matthieu, JM; Monnet-Tschudi, F; Pouly, S; Storch, MK | 1 |
| Chelliah, J; Freemerman, AJ; Grant, S; Jarvis, WD; Wu-Pong, S | 1 |
| Badwey, JA; Ding, J; Ellis, BA; Heyworth, PG; Robinson, JM | 1 |
| Darwiche, N; De Luca, LM; Gartsbein, M; Hansen, L; Hennings, H; Lowry, D; Morgan, DL; Tennenbaum, T; Yuspa, SH | 1 |
| Hashimoto, Y; Inui, K; Okuda, M; Takami, K; Uwai, Y | 1 |
| Kaul, A; Khanduja, KL | 1 |
| Acs, P; Blumberg, PM; Bögi, K; Lorenzo, PS; Szállási, Z; Wagner, GS | 1 |
| Holmgren, A; Kumar, S | 1 |
| Grant, S; Vrana, JA | 1 |
| Alexandre, D; Chada, S; Chen, Y; Christiansen, KA; Fisher, PB; Goldstein, NI; Gopalkrishnan, RV; Huang, EY; Huberman, E; Jiang, H; Kang, D; Lebedeva, IV; Leszczyniecka, M; Lin, JJ; Madireddi, MT; Mei, MX; Mhashilkar, AB; Pestka, S; Sivo, F; Su, Z; Vozhilla, N | 1 |
| Gábor, M | 1 |
| Abdel-Fattah, R; Glick, A; Hennings, H; Maiberger, P; Rehman, I | 1 |
| Chiba, K; Goto, M; Gusovsky, F; Inoue, Y; Ishii, N; Kuboi, Y; Muramoto, K; Omae, T; Shirota, H; Wang, YJ | 1 |
| Costa, J; Delang, L; Leyssen, P; Litaudon, M; Neyts, J; Nothias-Scaglia, LF; Pannecouque, C; Paolini, J; Renucci, F; Roussi, F | 1 |
| Gaté, L; Guichard, Y; Savoy, C | 1 |
4 review(s) available for tetradecanoylphorbol acetate and mezerein
| Article | Year |
|---|---|
Modulation of cell communication and carcinogenesis.
Topics: Animals; Antigens, Surface; Calcium; Carcinogens; Carrier Proteins; Cell Adhesion Molecules; Cell Communication; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diterpenes; Humans; Intercellular Junctions; Mice; Mice, Inbred BALB C; Permeability; Phorbol Esters; Phospholipids; Protein Kinases; Sodium-Hydrogen Exchangers; Sodium-Potassium-Exchanging ATPase; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Regeneration and the mechanism of epidermal tumor promotion.
Topics: Acetates; Acetic Acid; Animals; Carcinogens; Cell Differentiation; Connective Tissue Cells; Diterpenes; Epidermal Cells; Humans; Hyperplasia; Inflammation; Models, Biological; Regeneration; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Specificity and mechanism(s) of promoter inhibitors in multistage promotion.
Topics: Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Epidermal Cells; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Polyamines; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1982 |
Models of acute inflammation in the ear.
Topics: Alkynes; Animals; Anthralin; Arachidonic Acid; Cantharidin; Capsaicin; Carrageenan; Croton Oil; Dermatitis; Disease Models, Animal; Diterpenes; Edema; Foot; Inflammation; Irritants; Male; Mice; Models, Animal; Mustard Plant; Otitis Externa; Plant Extracts; Plant Oils; Rats; Reproducibility of Results; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 2003 |
182 other study(ies) available for tetradecanoylphorbol acetate and mezerein
| Article | Year |
|---|---|
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Diterpenes; Humans; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Retinoic acid inhibition of the comitogenic action of mezerein and phorbol esters in bovine lymphocytes.
Topics: Animals; Cattle; Diterpenes; DNA; Drug Synergism; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1978 |
Altered regulation of arachidonic acid metabolism by SV40 immortalized human urothelial cells.
Topics: Arachidonic Acid; Aspirin; Bradykinin; Calcimycin; Cell Line, Transformed; Dinoprostone; Diterpenes; Microsomes; Prostaglandin-Endoperoxide Synthases; Simian virus 40; Terpenes; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
Oxygen radical-dependent epoxidation of (7S,8S)-dihydroxy-7,8-dihydrobenzo[a]pyrene in mouse skin in vivo. Stimulation by phorbol esters and inhibition by antiinflammatory steroids.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenosine Triphosphate; Animals; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Diterpenes; DNA; Dose-Response Relationship, Drug; Female; Fluocinolone Acetonide; Isoenzymes; Kinetics; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxidase; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Modulation of the antigenic phenotype of human breast carcinoma cells by modifiers of protein kinase C activity and recombinant human interferons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzyl Alcohols; Breast Neoplasms; Carcinoma; Cell Adhesion Molecules; Cell Division; Diterpenes; Female; Glycoproteins; Histocompatibility Antigens Class II; Humans; Intercellular Adhesion Molecule-1; Interferon Type I; Interferon-gamma; Isoquinolines; Phenotype; Piperazines; Protein Kinase C; Proto-Oncogene Proteins; Receptor, ErbB-2; Recombinant Proteins; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Tumor promoters induce basic fibroblast growth factor gene expression in human dermal fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinogens; Cell Line; Diterpenes; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Fibroblasts; Gene Expression; Isoquinolines; Phorbol Esters; Piperazines; RNA, Messenger; Skin; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Diterpenes; Enzyme Activation; Female; Genetic Variation; Kinetics; Ligands; Molecular Sequence Data; N-Methylaspartate; Oligodeoxyribonucleotides; Oocytes; Polyamines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing; Sphingosine; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1992 |
Tumour promoting phorbol esters activate phospholipase D in mouse skin.
Topics: Animals; Butanols; Diterpenes; Enzyme Activation; Female; Glycerophospholipids; Mice; Mice, Inbred Strains; Palmitic Acid; Palmitic Acids; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Skin; Terpenes; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Activators of protein kinase C decrease serotonin transport in human platelets.
Topics: Alkaloids; Biological Transport; Blood Platelets; Diterpenes; Enzyme Activation; Humans; Protein Kinase C; Serotonin; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Skin carcinomas and micronucleus induction in epidermal keratinocytes following 12-O-tetradecanoylphorbol-13-acetate and mezerein treatment.
Topics: Animals; Carcinogens; Diterpenes; Female; Keratinocytes; Kinetics; Mice; Micronucleus Tests; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Differentiation of the U937 macrophage cell line removes an early block of HSV-1 infection.
Topics: Cell Differentiation; Cell Nucleus; Cholecalciferol; Diterpenes; Herpes Simplex; Humans; Macrophages; RNA, Viral; Simplexvirus; Terpenes; Tetradecanoylphorbol Acetate; Virus Replication | 1991 |
Effect of tumour promoters and non-genotoxic carcinogens on terminal differentiation and proliferation in mouse teratoma XB2 cells cultured in low calcium medium.
Topics: Animals; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cocarcinogenesis; Diterpenes; Keratins; Lyngbya Toxins; Mice; Teratoma; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Role of protein kinase C in IFN-mediated Ly-6E antigen induction.
Topics: Animals; Antigens, Ly; Antigens, Surface; Calmodulin; Cell Line; Diterpenes; Enzyme Activation; Gene Expression; In Vitro Techniques; Interferons; Mice; Protein Kinase C; RNA, Messenger; Terpenes; Tetradecanoylphorbol Acetate; Thy-1 Antigens; Time Factors | 1990 |
Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils.
Topics: Alkaloids; Cell Membrane; Diglycerides; Diterpenes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Neutrophils; Potassium; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Valinomycin | 1991 |
Effect of protein kinase C activators on the phosphorylation and the surface expression of the CDw50 leukocyte antigen.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; Concanavalin A; Cross-Linking Reagents; Diterpenes; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Isoquinolines; Kinetics; Lymphocytes; Phorbol 12,13-Dibutyrate; Phosphorylation; Phytohemagglutinins; Piperazines; Precipitin Tests; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Induction of ornithine decarboxylase in specific subpopulations of murine epidermal cells following multiple exposures to 12-O-tetradecanoylphorbol-13-acetate, mezerein and ethyl phenylpropriolate.
Topics: Alkynes; Animals; Carcinogens; Diterpenes; Enzyme Induction; Epidermis; Female; Flow Cytometry; Immunohistochemistry; Mice; Ornithine Decarboxylase; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1992 |
Modulation of synovial fibroblast plasminogen activator and plasminogen activator inhibitor production by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Diterpenes; Fibroblasts; Humans; Interleukin-1; Isoquinolines; Lyngbya Toxins; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; RNA, Messenger; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Effect of protein kinase C activating agents on respiratory glycoconjugate release from feline airways.
Topics: Animals; Cats; Chromatography, Gel; Chromatography, High Pressure Liquid; Diterpenes; Eicosanoids; Enzyme Activation; Glycoconjugates; Kinetics; Lung; Masoprocol; Organ Culture Techniques; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Vascular responsiveness to protein kinase C activators in mineralocorticoid-hypertensive rats.
Topics: Animals; Calcium Channels; Desoxycorticosterone; Diterpenes; Enzyme Activation; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Rats, Inbred Strains; Sodium, Dietary; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Enhanced poly ADP-ribosylation in human leukemia lymphocytes and ovarian cancers.
Topics: Adolescent; Adult; Biomarkers, Tumor; Carcinogens; Cell Division; Diterpenes; DNA Damage; Female; Humans; Kinetics; Leukemia; Lymphocytes; Middle Aged; NAD; Ovarian Neoplasms; Poly(ADP-ribose) Polymerases; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Cepharanthine inhibits two-stage tumor promotion by 12-O-tetradecanoylphorbol 13-acetate and mezerein on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Alkaloids; Animals; Benzylisoquinolines; Carcinogens; Diterpenes; Drug Interactions; Enzyme Induction; Female; Immunity, Cellular; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
A rapid colorimetric microassay to detect agonists/antagonists of protein kinase C based on adherence of EL-4.IL-2 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carcinogens; Cell Adhesion; Colorimetry; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Isoquinolines; Lactams; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Reproducibility of Results; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1991 |
Evidence that protein kinase C regulates allosensitized T lymphocyte function.
Topics: Animals; Cell Division; Diglycerides; Diterpenes; Female; Immunization; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Kinase C; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C influences rat pulmonary vascular reactivity.
Topics: Animals; Calcium; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Hydrogen; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Pulmonary Artery; Rats; Rats, Inbred Strains; Sodium; Terpenes; Tetradecanoylphorbol Acetate; Vasoconstriction | 1990 |
S/RV Cri-ba, a hairless mouse strain sensitive to skin tumorigenesis by suboptimal doses of 7,12-dimethylbenz[a]anthracene, initiation-promotion and two stage promotion protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Mice, Hairless; Papilloma; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Development of an in vitro analogue of initiated mouse epidermis to study tumor promoters and antipromoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Antineoplastic Agents; Benzoyl Peroxide; Carcinogens; Cell Communication; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Diterpenes; Keratinocytes; Mice; Mice, Inbred BALB C; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Chronic inhibitory effect of follicle-stimulating hormone (FSH)-suppressing protein (FSP) or follistatin on activin- and gonadotropin-releasing hormone-stimulated FSH synthesis and secretion in cultured rat anterior pituitary cells.
Topics: Activins; Animals; Binding Sites; Cells, Cultured; Diterpenes; Enzyme Activation; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Gonadotropin-Releasing Hormone; Inhibins; Kinetics; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Phorbol myristate acetate inhibits HeLa 229 invasion by Bordetella pertussis and other invasive bacterial pathogens.
Topics: Actins; Bacteria; Bacterial Adhesion; Bordetella pertussis; Cytochalasin B; Cytochalasin D; Cytoskeletal Proteins; Diterpenes; Fluorescent Dyes; HeLa Cells; Humans; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Vinculin | 1990 |
Acute inhibitory effect of follicle-stimulating hormone-suppressing protein (FSP) on gonadotropin-releasing hormone-stimulated gonadotropin secretion in cultured rat anterior pituitary cells.
Topics: Animals; Calcimycin; Cells, Cultured; Diterpenes; Enzyme Activation; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Melitten; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Effect of tumour promoters on poly ADP-ribosylation in human epidermoid carcinoma HeP2 cells.
Topics: Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; Enzyme Activation; Humans; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Reduction of muscarinic receptor density and of guanine nucleotide-stimulated phosphoinositide hydrolysis in human SH-SY5Y neuroblastoma cells following long-term treatment with 12-O-tetradecanoylphorbol 13-acetate or mezerein.
Topics: Calcium; Culture Media; Cytoplasm; Diterpenes; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Inositol Phosphates; Neuroblastoma; Osmolar Concentration; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Tumor Cells, Cultured | 1990 |
Effect of inhibin on activators of protein kinase-C and calcium-mobilizing agents which stimulate secretion of gonadotropins in vitro: implication of a postgonadotropin-releasing hormone receptor effect of inhibin on gonadotropin release.
Topics: Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Diterpenes; Enzyme Activation; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Inhibins; Luteinizing Hormone; Male; Melitten; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, LHRH; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Vascular responsiveness to phorbol esters in coarctation-hypertensive rats.
Topics: Animals; Aorta, Thoracic; Aortic Coarctation; Carcinogens; Diterpenes; Dose-Response Relationship, Drug; Hypertension; Male; Muscle, Smooth, Vascular; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Regulation of mRNA expression of 3 beta-hydroxy-5-ene steroid dehydrogenase in porcine granulosa cells in culture: a role for the protein kinase-C pathway.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Female; Granulosa Cells; Kinetics; Luteinizing Hormone; Protein Kinase C; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Activation of protein kinase C inhibits extraction of serotonin by perfused rat lung in situ.
Topics: Alkaloids; Animals; Carcinogens; Diterpenes; Enzyme Activation; Kinetics; Lung; Male; Papaverine; Perfusion; Phorbol Esters; Protein Kinase C; Pulmonary Circulation; Rats; Rats, Inbred Strains; Serotonin; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Effects of retinoic acid on epidermal DNA synthesis induced by 12-O-tetradecanoylphorbol-13-acetate, mezerein or ethylphenylpropiolate in hairless mice.
Topics: Alkynes; Animals; Carcinogens; Diterpenes; DNA; Female; Mice; Mice, Hairless; Skin; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Regulation of ornithine decarboxylase in rat kidney.
Topics: Animals; Carcinogens; Cycloheximide; Dactinomycin; Diterpenes; Folic Acid; Homeostasis; Kidney; Liver; Male; Nephrectomy; Ornithine Decarboxylase; Protein Kinase C; Rats; Rats, Inbred Strains; Reference Values; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Responses of human cervical keratinocytes in vitro to tumour promoters and diethylstilboestrol.
Topics: Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cervix Uteri; Clone Cells; Diethylstilbestrol; Diterpenes; Female; Humans; Keratins; Kinetics; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Induction of papillomas with a high probability of conversion to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Diterpenes; DNA; Female; Keratins; Mice; Mice, Inbred Strains; Papilloma; Probability; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cattle; Colforsin; Diterpenes; Drug Synergism; Enzyme Activation; Ethers; In Vitro Techniques; Ionomycin; Muscle Contraction; Muscle, Smooth; Nifedipine; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Novel serine phosphorylation of pp60c-src in intact cells after tumor promoter treatment.
Topics: Animals; Carcinogens; Cell Line; Diterpenes; Lung; Mink; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Terpenes; Tetradecanoylphorbol Acetate; Trypsin | 1986 |
Identification of tumor promoters by their inhibitory effect on intercellular transfer of lucifer yellow.
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cells, Cultured; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; Intercellular Junctions; Isoquinolines; Lyngbya Toxins; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Further characterization of skin tumor promotion and progression by mezerein in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Diterpenes; DNA; Female; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Enzyme Activation; Female; Hyperplasia; Mice; Mice, Inbred Strains; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Arachidonic acid potentiates superoxide anion radical production by murine peritoneal macrophages stimulated with tumor promoters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Diterpenes; Female; Kinetics; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phorbol Esters; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein.
Topics: Alkaloids; Animals; Diglycerides; Diterpenes; Glycerides; Guinea Pigs; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Differential effects of tumor promoters on P210bcr-abl expression.
Topics: Antineoplastic Agents, Phytogenic; Cell Division; Diterpenes; Dose-Response Relationship, Drug; Fusion Proteins, bcr-abl; Gene Expression; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1989 |
Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells.
Topics: Animals; Calcium; Carbachol; Cytoplasm; Dimethyl Sulfoxide; Diterpenes; Enzyme Activation; Gallopamil; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Mice, Obese; Phosphoproteins; Potassium; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Tolbutamide | 1989 |
Modulation of endothelial cell expression of intercellular adhesion molecule 1 by protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, Surface; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Diterpenes; Endothelium, Vascular; Enzyme Activation; Humans; Isoquinolines; Kinetics; Membrane Glycoproteins; Phorbol Esters; Piperazines; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.
Topics: Animals; Carcinogens; Diglycerides; Diterpenes; Female; Glycerides; Mice; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Neurogenic component of phorbol ester-induced mouse skin inflammation.
Topics: Administration, Topical; Animals; Diterpenes; Dose-Response Relationship, Drug; Erythema; Female; Hyperplasia; Inflammation; Mice; Mice, Inbred Strains; Phorbol Esters; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Comparative histomorphometric changes in SENCAR mouse epidermis in response to multiple treatments with complete and stage-specific tumor promoting agents.
Topics: Acetone; Alkanes; Alkynes; Animals; Carcinogens; Diterpenes; Epidermis; Female; Langerhans Cells; Leukocytes; Male; Mice; Mice, Inbred Strains; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
The effects of the anti-tumor agent mezerein on the cytotoxic capacity and oxidative metabolism of human blood cells.
Topics: Antineoplastic Agents, Phytogenic; Blood Cells; Cell Survival; Diterpenes; Granulocytes; Humans; In Vitro Techniques; Monocytes; Neutrophils; Oxidation-Reduction; Phagocytosis; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes.
Topics: Adenosine Triphosphate; Cobra Neurotoxin Proteins; Cyclic AMP; Diterpenes; Enzyme Activation; Erythrocytes; Humans; Lipids; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Protein Kinases; Terpenes; Tetradecanoylphorbol Acetate; Trifluoperazine | 1988 |
Enhancement of bovine papillomavirus-induced cell transformation by tumour promoters.
Topics: Animals; Bovine papillomavirus 1; Carcinogens; Cell Transformation, Viral; Chromosome Aberrations; Diterpenes; Mice; Mice, Inbred C3H; Micronucleus Tests; Papillomaviridae; Phorbol Esters; Sister Chromatid Exchange; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Protein kinase C-activating tumor promoters enhance the differentiation of astrocytes in aggregating fetal brain cell cultures.
Topics: Animals; Astrocytes; Brain; Carcinogens; Cell Aggregation; Cell Differentiation; Cells, Cultured; Diterpenes; Embryo, Mammalian; Enzyme Activation; Epidermal Growth Factor; Glutamate-Ammonia Ligase; Protein Kinase C; Rats; Rats, Inbred Strains; Telencephalon; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Effects of tumor promoters (mezerein, teleocidin and palytoxin) on growth hormone secretion from rat anterior pituitary cells cultured in monolayer.
Topics: Acrylamides; Animals; Carcinogens; Cells, Cultured; Cnidarian Venoms; Diterpenes; Enzyme Activation; Growth Hormone; Lyngbya Toxins; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Qualitative and quantitative effects on epidermal Langerhans (Ia+) and Thy-1+ dendritic cells following topical application of phorbol diesters and mezerein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinogens; Dendritic Cells; Diterpenes; Histocompatibility Antigens Class II; Langerhans Cells; Mice; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thy-1 Antigens | 1988 |
Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells.
Topics: Animals; Bryostatins; Cell Division; Diterpenes; DNA Replication; Enzyme Activation; Lactones; Lung Neoplasms; Macrolides; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Tumour-promoting and hyperplastic effects of phorbol and daphnane esters in CD-1 mouse skin and a synergistic effect of calcium ionophore with the non-promoting activator of protein kinase C, sapintoxin A.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Diterpenes; Female; Hyperplasia; Phorbol Esters; Rats; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Induction of nitroblue tetrazolium reduction in mouse peritoneal macrophages by tumour promoters and inhibition of the induced nitroblue tetrazolium reduction by some inhibitors.
Topics: Acetophenones; Animals; Carcinogens; Cells, Cultured; Diterpenes; Female; Free Radicals; Lyngbya Toxins; Macrophages; Mice; Mice, Inbred Strains; Nitroblue Tetrazolium; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Tretinoin | 1985 |
Cholera toxin, a potent inducer of epidermal hyperplasia but with no tumor promoting activity in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cholera Toxin; Cocarcinogenesis; Cyclic AMP; Diterpenes; Enzyme Induction; Epidermis; Hyperplasia; Mice; Ornithine Decarboxylase; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Phorbol diacetate inhibits superoxide anion radical production and tumor promotion by mezerein.
Topics: Animals; Carcinogens; Diterpenes; Female; Free Radicals; Hyperplasia; Macrophages; Mice; Phorbol Esters; Skin; Skin Neoplasms; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Protein kinase C regulates leukotriene B4 receptors in human neutrophils.
Topics: Cell Membrane; Diglycerides; Diterpenes; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Protein Kinase C; Receptors, Immunologic; Receptors, Leukotriene B4; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Possible involvement of reorganization of actin filaments, induced by tumor-promoting phorbol esters, in changes in colony shape and enhancement of proliferation of cultured epithelial cells.
Topics: Actins; Animals; Cell Division; Cyclic AMP; Diterpenes; Dogs; Epithelial Cells; Epithelium; Kidney; Microscopy, Fluorescence; Phorbol 12,13-Dibutyrate; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Second stage tumor promoters: differences in biological potency and phorbol ester receptor affinity in C6 cells.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Cyclic AMP; Diterpenes; Glioma; Glycerolphosphate Dehydrogenase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Phosphorylation and inactivation of rat hepatocyte glycogen synthase by phorbol esters and mezerein.
Topics: Animals; Cyanogen Bromide; Diterpenes; Glycogen Synthase; Isoelectric Focusing; Liver; Peptide Fragments; Phorbol Esters; Phosphates; Phosphorylation; Rats; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Trypsin | 1986 |
The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alprostadil; Animals; Diterpenes; Enzyme Induction; Female; Indomethacin; Mice; Mice, Inbred Strains; Models, Biological; Neoplasms; Ornithine Decarboxylase; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Decreased sulfation of cellular chondroitin sulfate in response to activators of protein kinase C.
Topics: Cell Differentiation; Cell Line; Chondroitin; Chondroitin Sulfates; Diglycerides; Diterpenes; Enzyme Activation; Humans; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Phorbol ester-induced alteration of protein kinase C catalytic properties occurs at the membrane level and is not reproduced by physiological stimuli.
Topics: Animals; Carcinogens; Cell Compartmentation; Cell Line; Cell Membrane; Diglycerides; Diterpenes; Lyngbya Toxins; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Substrate Specificity; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Induction of human interferon gamma with phorbol esters and phytohemagglutinin.
Topics: Cell Separation; Culture Media; Diterpenes; Humans; Interferon Inducers; Interferon-gamma; Lymphocytes; Phytohemagglutinins; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
The induction of IFN-gamma production and m-RNAs of interleukin 2 and IFN-gamma by phorbol esters and a calcium ionophore.
Topics: Calcimycin; Carcinogens; Cell Line; Cycloheximide; Diterpenes; Enterotoxins; Humans; Interferon-gamma; Interleukin-2; Protein Biosynthesis; RNA, Messenger; Staphylococcus aureus; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation.
Topics: Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents.
Topics: Animals; Anthracenes; Benzo(a)pyrene; Carcinogens; Diterpenes; Lyngbya Toxins; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Skin; Skin Neoplasms; Species Specificity; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
[Possibility of identifying tumor promoters by their inhibitory action on the intercellular exchange of lucifer yellow].
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cell Line; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; In Vitro Techniques; Isoquinolines; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Thrombin and C-kinase activators potentiate calcium-stimulated arachidonic acid release in human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Diglycerides; Diterpenes; Drug Synergism; Humans; Isoquinolines; Phospholipids; Piperazines; Protein Kinase C; Pyrimidinones; Terpenes; Tetradecanoylphorbol Acetate; Thiazoles; Thrombin | 1987 |
Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
Topics: Animals; Calcimycin; Diterpenes; Drug Synergism; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
The development of contact hypersensitivity in mouse skin is suppressed by tumor promoters.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Dinitrochlorobenzene; Diterpenes; Female; Immunosuppressive Agents; Mice; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Differential effects of diacylglycerols and 12-O-tetradecanoylphorbol-13-acetate on protein phosphorylation and cell proliferation of tumor promoter-dependent leukemia cell line A65T.
Topics: Animals; Brain; Calcium; Caprylates; Carcinogens; Cell Division; Cell Line; Diglycerides; Diterpenes; Enzyme Activation; Glycerides; Kinetics; Lyngbya Toxins; Mice; Molecular Weight; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of hexose transport by human polymorphonuclear leukocytes: a possible role for protein kinase C.
Topics: Biological Transport, Active; Calcimycin; Cytochalasin B; Deoxyglucose; Diglycerides; Diterpenes; Hexoses; Humans; Isomerism; Neutrophils; Protein Kinase C; Protein Kinases; Terpenes; Tetradecanoylphorbol Acetate; Trifluoperazine | 1985 |
Dual actions of phorbol esters on cytosolic free Ca2+ concentrations and reconstitution with ionomycin of acute thyrotropin-releasing hormone responses.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans Proteins; Calcium; Carrier Proteins; Cells, Cultured; Cytosol; Diterpenes; Egtazic Acid; Epidermal Growth Factor; Ethers; Insulin; Ionomycin; Phorbols; Pituitary Gland; Potassium; Protein Kinase C; Protein Kinases; Rats; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1985 |
Phorbol ester stimulation of sphingomyelin synthesis in human leukemic HL60 cells.
Topics: Bryostatins; Cell Line; Choline; Diterpenes; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Sphingomyelins; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Critical comparison of histological and morphometric changes in SENCAR mouse epidermis in response to n-dodecane, 12-O-tetradecanoylphorbol-13-acetate and mezerein.
Topics: Alkanes; Animals; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Female; Mice; Mice, Inbred Strains; Microscopy, Electron; Mitochondria; Mitotic Index; Skin; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Effects of TPA dose variation and mezerein on skin tumorigenesis by initiation promotion protocol in S/RV Cri mice.
Topics: Animals; Carcinogens; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Relation between the organization of spectrin and of membrane lipids in lymphocytes.
Topics: Animals; Cell Adhesion; Cell Separation; Cells, Cultured; Diterpenes; Flow Cytometry; Fluorescent Antibody Technique; Humans; Lymphocytes; Membrane Lipids; Mice; Spectrin; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Tetrathionic Acid; Thymus Gland | 1988 |
Differential effects of phorbol ester tumor promoters on 3-methylcholanthrene-induced epithelial and mesenchymal skin tumorigenesis.
Topics: Animals; Carcinoma; Diterpenes; Female; Mesenchymoma; Methylcholanthrene; Mice; Mice, Inbred Strains; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of choline transport in cultured cells induced by 12-O-tetradecanoylphorbol-13-acetate: one of the earliest phenomena induced by the tumor promoter.
Topics: Animals; Calcium; Calmodulin; Cells, Cultured; Choline; Diterpenes; Protein Kinase C; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
Differential effects of various protein kinase C activators on protein phosphorylation in human acute myeloblastic leukemia cell line KG-1 and its phorbol ester-resistant subline KG-1a.
Topics: Bryostatins; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Drug Resistance; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phosphorylation; Protein Kinase C; Proteins; Pyrimidinones; Terpenes; Tetradecanoylphorbol Acetate; Thiazoles | 1987 |
Characterization of an inbred strain of the SENCAR mouse that is highly sensitive to phorbol esters.
Topics: Animals; Diterpenes; Female; Histocompatibility Testing; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Skin Transplantation; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Enhanced vascular reactivity to protein kinase C activators in genetically hypertensive rats.
Topics: Animals; Blood Vessels; Calcium; Diterpenes; Enzyme Activation; Hypertension; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Terpenes; Tetradecanoylphorbol Acetate; Vasoconstriction | 1987 |
Mechanism of mouse skin tumor promotion by n-dodecane.
Topics: Acetone; Alkanes; Animals; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Effect of mouse skin tumor promoters upon [3H]uridine exchange and focus formation in cultures of C3H/10T1/2 mouse fibroblasts.
Topics: Animals; Carcinogens; Cells, Cultured; Dimethyl Sulfoxide; Diterpenes; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Polychlorinated Dibenzodioxins; Pregnancy; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Uridine | 1986 |
Cholinergic neurons of fetal rat telencephalon in aggregating cell culture respond to NGF as well as to protein kinase C-activating tumor promoters.
Topics: Animals; Cells, Cultured; Cholinergic Fibers; Diterpenes; Nerve Growth Factors; Rats; Rats, Inbred Strains; Stimulation, Chemical; Telencephalon; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of protein kinase C mediated signal transduction by tamoxifen. Importance for antitumour activity.
Topics: Diglycerides; Diterpenes; Humans; Luminescent Measurements; Neutrophils; Oxygen Consumption; Protein Kinase C; Tamoxifen; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Hydrogen peroxide formation and DNA base modification by tumor promoter-activated polymorphonuclear leukocytes.
Topics: Diterpenes; DNA; Humans; Hydrogen Peroxide; Kinetics; Neutrophils; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Induction of megakaryocytic colony-stimulating activity in mouse skin by inflammatory agents and tumor promoters.
Topics: Animals; Betamethasone; Diterpenes; Dose-Response Relationship, Drug; Growth Substances; Inflammation; Megakaryocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Skin; Skin Physiological Phenomena; Terpenes; Tetradecanoylphorbol Acetate; Thrombocytosis | 1987 |
Induction and desensitization of plasminogen activator gene expression by tumor promoters.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcitonin; Carcinogens; Cell Line; Cycloheximide; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1985 |
Induction and characterization of lymphotoxins from tumor promoter-synergized, lectin-stimulated human lymphocytes in vitro.
Topics: Carcinogens; Chromatography, Affinity; Chromatography, Ion Exchange; Diterpenes; Humans; In Vitro Techniques; Lymphocytes; Lymphotoxin-alpha; Phorbol Esters; Phorbols; Phytohemagglutinins; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diterpenes; Female; Mice; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Diacylglycerols and mezerein activate neutrophils by a phorbol myristate acetate-like mechanism.
Topics: Arachidonic Acid; Arachidonic Acids; Biomechanical Phenomena; Cations, Divalent; Cell Aggregation; Cytochalasin B; Diglycerides; Diterpenes; Drug Resistance; Glycerides; Humans; Neutrophils; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
12-O-tetradecanoylphorbol-13-acetate promotes tumors prior to initiation in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Enzyme Induction; Female; Mice; Models, Biological; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Effects of tumor promoters on the expression of a tumor-related multigenic set in human cells.
Topics: Actins; Burkitt Lymphoma; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; Diterpenes; DNA, Neoplasm; Gene Expression Regulation; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Lyngbya Toxins; Proto-Oncogenes; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin | 1985 |
Role of protein synthesis in induction of interferon-gamma by mitogens in human lymphocytes.
Topics: Blood Proteins; Culture Media; Cycloheximide; Diterpenes; Drug Synergism; Gene Expression Regulation; Humans; Interferon Inducers; Interferon-gamma; Lymphocyte Activation; Mitogens; RNA, Messenger; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.
Topics: Acetone; Alkynes; Animals; Carcinogens; Cycloheximide; Diterpenes; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells.
Topics: Animals; Cell Adhesion; Diglycerides; Diterpenes; Lung Neoplasms; Male; Mice; Mitogens; Neoplasm Metastasis; Phorbol Esters; Phorbols; Protein Kinases; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Characterization of a human teratocarcinoma cell assay for inhibitors of metabolic cooperation.
Topics: Biological Assay; Cell Communication; Diterpenes; Humans; Hypoxanthine Phosphoribosyltransferase; Intercellular Junctions; Karyotyping; Phorbol Esters; Teratoma; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
The role of C-kinase in the physiological activation of the neutrophil oxidase. Evidence from using pharmacological manipulation of C-kinase activity in intact cells.
Topics: Animals; Diglycerides; Diterpenes; Enzyme Activation; In Vitro Techniques; Latex; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Phorbols; Protein Kinase C; Rats; Terpenes; Tetradecanoylphorbol Acetate | 1985 |
Induction of dark keratinocytes by 12-O-tetradecanoylphorbol-13-acetate and mezerein as an indicator of tumor-promoting efficiency.
Topics: Animals; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Keratins; Mice; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
Effects of the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate on newly synthesized proteins in mouse epidermis.
Topics: Animals; Diterpenes; Electrophoresis, Polyacrylamide Gel; Epidermis; Fluocinolone Acetonide; Hyperplasia; Keratins; Mice; Molecular Weight; Phorbol Esters; Phorbols; Protein Biosynthesis; Proteins; Terpenes; Tetradecanoylphorbol Acetate | 1981 |
Quantitative evaluation of dark keratinocytes induced by several promoting and hyperplasiogenic agents: their use as an early morphological indicator of tumor-promoting action.
Topics: Alkynes; Anthralin; Calcimycin; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Hyperplasia; Keratins; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
The effects of tumour promoters on the multiplication and morphology of cultured human epidermal keratinocytes.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Cells, Cultured; Cytological Techniques; Diterpenes; Humans; Keratins; Mice; Microscopy, Electron; Phorbol Esters; Phorbols; Skin; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Trypan Blue | 1982 |
Effects of tumor promoters on the rate and commitment to terminal differentiation of subpopulations of murine keratinocytes.
Topics: Calcimycin; Carcinogens; Cell Differentiation; Cells, Cultured; Centrifugation, Density Gradient; Diterpenes; Keratins; Kinetics; Phorbol Esters; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Tumour promoter-mediated reversible inhibition of cell-cell communication (electrical coupling). Relationship with phorbol ester binding and de novo macromolecule synthesis.
Topics: Binding Sites; Cell Communication; Cell Line; Cycloheximide; Dactinomycin; Diterpenes; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Biosynthesis; RNA; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Differential effects of complete and second-stage tumour promoters in normal but not transformed human and mouse keratinocytes.
Topics: Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Drug Resistance; Epidermal Cells; Epidermis; Humans; Keratins; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Activation of protein kinase C by non-phorbol tumor promoter, mezerein.
Topics: Animals; Brain; Carcinogens; Diterpenes; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipids; Protein Binding; Protein Kinase C; Protein Kinases; Rats; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Retinoid inhibition of superoxide anion radical production by human polymorphonuclear leukocytes stimulated with tumor promoters.
Topics: Alkaloids; Antipain; Cocarcinogenesis; Diterpenes; Humans; Indoles; Inflammation; Lyngbya Toxins; Neutrophils; Oxygen; Phorbol Esters; Phorbols; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1980 |
The role of free oxygen radicals in tumor promotion and carcinogenesis.
Topics: Carcinogens; Cell Membrane; Cocarcinogenesis; Diterpenes; Free Radicals; Hydrogen Peroxide; Neutrophils; Oxygen; Phorbol Esters; Phorbols; Protease Inhibitors; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Vitamin A | 1982 |
Enhancement of hormone action by a phorbol ester and anti-tubulin alkaloids involves different mechanisms.
Topics: Alprostadil; Animals; Antineoplastic Agents, Phytogenic; Cell Line; Clone Cells; Cyclic AMP; Diterpenes; Isoproterenol; Kinetics; Leukemia, Experimental; Mice; Phorbol Esters; Phorbols; Prostaglandins E; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Stimulation of growth of human melanocytes by tumor promoters.
Topics: Alkaloids; Cell Division; Cell Line; Cholera Toxin; Diterpenes; Humans; Lyngbya Toxins; Male; Melanocytes; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Coproduction of interleukin-2 and interferon-gamma in human mononuclear cells.
Topics: Cells, Cultured; Diterpenes; Humans; Interferon-gamma; Interleukin-2; Kinetics; Lymphocyte Activation; Lymphocytes; Phorbol Esters; Phytohemagglutinins; Terpenes; Tetradecanoylphorbol Acetate; Thymidine | 1983 |
Tumor promoters induce a specific morphological signature in the nuclear matrix-intermediate filament scaffold of Madin-Darby canine kidney (MDCK) cell colonies.
Topics: Alkaloids; Animals; Benzoyl Peroxide; Carcinogens; Cell Line; Diterpenes; Dogs; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Kidney; Lactones; Lyngbya Toxins; Microscopy, Electron; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
The proliferative response of low-density human cell cultures to tumor promoters and its relevance to carcinogenic mechanisms in vitro.
Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; Fibroblasts; Humans; Lyngbya Toxins; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Inhibitory effect of tumor promoting phorbol esters and mezerein on human mixed lymphocyte reaction.
Topics: Antineoplastic Agents, Phytogenic; Diterpenes; DNA; Humans; Lymphocyte Culture Test, Mixed; Lymphocytes; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1981 |
The relevance of gap junctions to stage I tumor promotion in mouse epidermis.
Topics: Animals; Cell Communication; Diterpenes; Dose-Response Relationship, Drug; Female; Fluocinolone Acetonide; Intercellular Junctions; Mice; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1984 |
Presence of specific binding sites for phorbol ester tumor promoters in human epidermal and dermal cells in culture but lack of down regulation in epidermal cells.
Topics: Binding Sites; Binding, Competitive; Cells, Cultured; Diterpenes; Epidermis; Humans; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Relationship between mezerein-mediated biological responses and phorbol ester receptor occupancy.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Dinoprostone; Diterpenes; Epidermal Growth Factor; Humans; Kinetics; Osteosarcoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Protein Kinase C; Receptors, Drug; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Reduced trisialoganglioside synthesis in chemically but not mos-transformed mouse epidermal cells.
Topics: Animals; Carbon Radioisotopes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Diterpenes; Epidermal Growth Factor; Gangliosides; Glucosamine; Mice; Phorbol Esters; Phorbols; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1984 |
Effects of tumor promoters on the frequency of metallothionein I gene amplification in cells exposed to cadmium.
Topics: Alkaloids; Animals; Cadmium; Carcinogens; Cell Line; Cricetinae; Cricetulus; Diterpenes; Gene Amplification; Genes; Lactones; Lung; Lyngbya Toxins; Metallothionein; Mollusk Venoms; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Phorbol ester tumor promoter affects the mouse epidermal gap junctions.
Topics: Animals; Cell Communication; Diterpenes; Female; Intercellular Junctions; Mice; Phorbol Esters; Phorbols; Skin; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Epidermal Cells; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1980 |
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
alpha-Difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin.
Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Carboxy-Lyases; Carcinogens; Diterpenes; Eflornithine; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbol Esters; Polyamines; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Glucocorticoid receptor levels in mouse skin after repetitive applications of 12-O-tetradecanoylphorbol-13-acetate and mezerein.
Topics: Administration, Topical; Animals; Diterpenes; Female; Mice; Phorbol Esters; Phorbols; Receptors, Glucocorticoid; Receptors, Steroid; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Effects of single applications of 12-O-tetradecanoylphorbol-13-acetate, mezerein, or ethylphenylpropiolate on DNA synthesis and polyamine levels in hairless mouse epidermis.
Topics: Alkynes; Animals; Antineoplastic Agents, Phytogenic; Diterpenes; DNA Replication; Female; Kinetics; Male; Mice; Mice, Nude; Phorbol Esters; Phorbols; Polyamines; Putrescine; Skin; Spermidine; Spermine; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on gamma radiation-induced DNA repair in resting bovine lymphocytes.
Topics: Animals; Cattle; Cells, Cultured; Centrifugation, Density Gradient; Dimethyl Sulfoxide; Diterpenes; DNA; DNA Repair; Gamma Rays; Interphase; Lymphocytes; Neoplasms; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Tumor promoter stimulation of phosphatidylcholine turnover in HeLa cells.
Topics: Choline; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipases; Phospholipids; Phosphorylcholine; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of intercellular communication by tumor promoters.
Topics: Animals; Carcinogens; Cell Communication; Cell Line; Diterpenes; Dose-Response Relationship, Drug; Hypoxanthine Phosphoribosyltransferase; Mice; Phorbol Esters; Phorbols; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Tumor-promoting phorbol esters and mezerien induce contraction in hydra.
Topics: Animals; Antineoplastic Agents, Phytogenic; Diterpenes; Hydra; Phorbol Esters; Phorbols; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Effects of phorbol ester tumor promoters and hyperplasiogenic agents on cytoplasmic glucocorticoid receptors in epidermis.
Topics: Alkynes; Animals; Carcinogens; Dexamethasone; Diterpenes; Epidermis; Female; Male; Mice; Phorbol Esters; Phorbols; Receptors, Glucocorticoid; Receptors, Steroid; Temperature; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Effect of tumor promoters on lipid peroxidation in mouse skin.
Topics: Age Factors; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Diterpenes; Glutathione Peroxidase; Kinetics; Lipid Peroxides; Male; Mice; Neoplasms, Experimental; Phorbol Esters; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
Expression of protein kinase C isozymes that are required for chondrogenesis of chick limb bud mesenchymal cells.
Topics: Animals; Cartilage; Cell Differentiation; Cells, Cultured; Chick Embryo; Diterpenes; Enzyme Inhibitors; Indoles; Isoenzymes; Limb Buds; Maleimides; Mesoderm; Naphthalenes; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Thrombin-induced increase of F-actin in human umbilical vein endothelial cells.
Topics: Actins; Alkaloids; Calcium; Capillary Permeability; Cells, Cultured; Cytoskeleton; Diterpenes; Endothelium, Vascular; Humans; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Umbilical Veins | 1994 |
Influence of protein kinase C activation on basophils from patients with atopic dermatitis in comparison with nonatopic controls.
Topics: Adolescent; Adult; Aged; Basophils; Bombesin; Dermatitis, Atopic; Diglycerides; Diterpenes; Eczema; Enzyme Activation; Female; Histamine; Histamine Release; Humans; Immunoglobulin E; Male; Middle Aged; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Comparison of tumour promoter-induced prostaglandin E2 release in human and rat keratinocytes.
Topics: Acetates; Acetic Acid; Animals; Anthralin; Biological Transport; Carcinogens; Cell Survival; Cells, Cultured; Dinoprostone; Diterpenes; Humans; Keratinocytes; Kinetics; Mouth Mucosa; Neutral Red; Rats; Sodium Dodecyl Sulfate; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Differential protein kinase C ligand regulation detected in vivo by a phenotypic yeast assay.
Topics: Animals; Base Sequence; Carcinogens; Catalysis; Cattle; Cell Division; Cloning, Molecular; Diterpenes; Drug Evaluation, Preclinical; Indoles; Lactams; Ligands; Molecular Sequence Data; Mutation; Phenotype; Protein Kinase C; Regulatory Sequences, Nucleic Acid; Saccharomyces cerevisiae; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Consumption of reduced-energy/low-fat diet or constant-energy/high-fat diet during mezerein treatment inhibited mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet, Fat-Restricted; Dietary Carbohydrates; Dietary Fats; Diterpenes; Energy Intake; Female; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
Tumour-promoting activity of ninhydrin on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Diterpenes; Female; Mice; Ninhydrin; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line.
Topics: Alkaloids; Biological Transport; Carrier Proteins; Cell Division; Colonic Neoplasms; Dipeptides; Diterpenes; Humans; Hydrogen; Kinetics; Protein Kinase C; Sodium; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
12-O-tetradecanoyl-phorbol-13-acetate (TPA) counteracts the cAMP up-regulation of the expression of the stimulatory guanine nucleotide binding protein (Gs alpha) and Gs alpha messenger RNA in cultured pig thyroid cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Gene Expression Regulation; GTP-Binding Proteins; Kinetics; Protein Kinase C; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1994 |
Inhibition of both stage I and stage II skin tumor promotion in SENCAR mice by a polyphenolic fraction isolated from green tea: inhibition depends on the duration of polyphenol treatment.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diterpenes; Flavonoids; Mice; Phenols; Plant Extracts; Polymers; Polyphenols; Skin Neoplasms; Tea; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate in human breast cancer cells.
Topics: Breast Neoplasms; Carcinogens; Cycloheximide; Diglycerides; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Protein Kinase C; Receptors, Prolactin; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Cytochalasin modulation of nicotinic cholinergic receptor expression and muscarinic receptor function in human TE671/RD cells: a possible functional role of the cytoskeleton.
Topics: Carbachol; Cell Line; Cytochalasins; Cytoskeleton; Diterpenes; Humans; Inositol Phosphates; Intracellular Membranes; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; RNA, Messenger; Terpenes; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Bradykinin regulates the expression of kininogen binding sites on endothelial cells.
Topics: Bradykinin; Calcium; Diterpenes; Endothelium, Vascular; Humans; In Vitro Techniques; Kininogens; Protein Kinase C; Receptors, Bradykinin; Receptors, Neurotransmitter; Receptors, Peptide; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation | 1993 |
The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers, Tumor; Diterpenes; Female; Immunohistochemistry; Integrin alpha6beta4; Kinetics; Mice; Mice, Inbred Strains; Papilloma; Risk Factors; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma, Squamous Cell; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Vitamin E is a complete tumor promoter in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Vitamin E | 1993 |
Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters.
Topics: Animals; Carcinogens; Catechin; Diterpenes; DNA; DNA Damage; Female; Hydrogen Peroxide; Inflammation; Mice; Mice, Inbred Strains; Neutrophils; Oxidation-Reduction; Phorbol Esters; Skin; Tamoxifen; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Diterpenes; DNA Replication; Female; Mice; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 1996 |
GABA rho1 receptor: inhibition by protein kinase C activators.
Topics: Alkaloids; Animals; Cyclic AMP; Diterpenes; Electrophysiology; Enzyme Activation; GABA Antagonists; Protein Kinase C; Receptors, GABA; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection; Xenopus laevis | 1995 |
Dietary retinoic acid inhibits mouse skin carcinogenesis irrespective of age at initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Antineoplastic Agents; Carcinogens; Diet; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1996 |
Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters.
Topics: Acetamides; Acetone; Anthracenes; Carcinogens; Cell Line, Transformed; Coumarins; Deoxyuridine; Dimethylformamide; Diterpenes; DNA, Viral; Mercaptopurine; Methotrexate; Mutagens; Nitroquinolines; Nucleic Acid Hybridization; Simian virus 40; Terpenes; Testosterone; Tetradecanoylphorbol Acetate; Thioacetamide; Virus Replication | 1996 |
Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization.
Topics: Alkyl and Aryl Transferases; Animals; Carcinoma; Cell Compartmentation; Cell Membrane; Cell Transformation, Neoplastic; Cytosol; Diterpenes; Enzyme Inhibitors; Mice; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transferases; Tretinoin | 1996 |
Activation of conventional mammalian protein kinase C isoforms expressed in budding yeast modulates the cell doubling time--a potential in vivo screen for protein kinase C activators.
Topics: Animals; Bryostatins; Cattle; Cell Division; Diterpenes; Enzyme Activation; Indoles; Isoenzymes; Lactams; Lactones; Macrolides; Phorbol Esters; Plasmids; Protein Kinase C; Saccharomyces cerevisiae; Sequence Deletion; Terpenes; Tetradecanoylphorbol Acetate | 1996 |
Transient expression of M-CSF is important for osteoclast-like cell differentiation in a monocytic leukemia cell line.
Topics: Acid Phosphatase; Animals; Calcitonin; Calcitriol; Carcinogens; Cell Differentiation; Cell Nucleus; Dexamethasone; Diterpenes; Drug Synergism; Gene Expression Regulation, Leukemic; Genes, fms; Genes, src; Humans; Interferon-gamma; Isoenzymes; Leukemia, Monocytic, Acute; Macrophage Colony-Stimulating Factor; Mice; Osteoclasts; Phenotype; Tartrate-Resistant Acid Phosphatase; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Attenuation of p53 expression and Bax down-regulation during phorbol ester mediated inhibition of apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Diterpenes; Down-Regulation; Genes, p53; Mice; Nitric Oxide; Nitric Oxide Synthase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Terpenes; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Up-Regulation | 1997 |
Demyelination induced by protein kinase C-activating tumor promoters in aggregating brain cell cultures.
Topics: Animals; Biomarkers; Brain; Carcinogens; Cell Aggregation; Cell Differentiation; Cells, Cultured; Demyelinating Diseases; Diterpenes; Enzyme Activation; Fibroblast Growth Factor 2; Gene Expression; Myelin Proteins; Oligodendroglia; Protein Kinase C; Rats; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
Topics: Antineoplastic Agents; Apoptosis; Bryostatins; Cell Cycle; Cytarabine; Diterpenes; DNA Fragmentation; Drug Synergism; Enzyme Activation; HL-60 Cells; Humans; Kinetics; Lactones; Macrolides; Oligonucleotides, Antisense; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proto-Oncogene Proteins c-myc; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Topical retinoic acid reduces skin papilloma formation but resistant papillomas are at high risk for malignant conversion.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers, Tumor; Carcinogens; Carcinoma, Basal Cell; Cell Transformation, Neoplastic; Disease Progression; Diterpenes; Female; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Papilloma; Phenotype; Precancerous Conditions; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Factors; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factors; Transforming Growth Factor beta; Tretinoin | 1998 |
Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney.
Topics: Animals; Anion Transport Proteins; Anions; Biological Transport; Carrier Proteins; Cell Membrane; Dicarboxylic Acids; Diterpenes; DNA Primers; DNA, Complementary; Female; Folic Acid; Glutarates; Kidney; Kinetics; Methotrexate; Oocytes; p-Aminohippuric Acid; Phorbol Esters; Probenecid; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1998 |
Polyphenols inhibit promotional phase of tumorigenesis: relevance of superoxide radicals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; Coumaric Acids; Diglycerides; Diterpenes; Ellagic Acid; Flavonoids; Glycerol; Hydrolyzable Tannins; Macrophages; Male; Mice; Phenols; Polymers; Polyphenols; Skin Neoplasms; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1998 |
Comparison of the roles of the C1a and C1b domains of protein kinase C alpha in ligand induced translocation in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Diterpenes; Indoles; Isoenzymes; Lactams; Mice; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Translocation, Genetic | 1999 |
Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcimycin; Calcium; Carcinogens; Cocarcinogenesis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Induction; Epidermis; Female; Fluocinolone Acetonide; Gene Expression Regulation; Glutaredoxins; Glutathione; Ionophores; Mice; Oxidation-Reduction; Oxidoreductases; Phorbol Esters; Protein Kinase C; Proteins; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thioredoxins; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1999 |
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins | 2001 |
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
Topics: Antigens, Neoplasm; Apoptosis; Base Sequence; Carcinoma; Cell Differentiation; Cell Division; Chromosomes, Human, Pair 1; Cloning, Molecular; Dimethyl Sulfoxide; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Genes; Genes, Tumor Suppressor; Glioblastoma; Growth Substances; HL-60 Cells; Humans; Interferon Type I; Interleukins; K562 Cells; Male; Melanocytes; Melanoma; Molecular Sequence Data; Molecular Weight; Neoplasm Proteins; Neoplasms; Organ Specificity; Osteosarcoma; Recombinant Fusion Proteins; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 2001 |
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methylnitronitrosoguanidine; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory respon
Topics: Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Croton Oil; Dinitrofluorobenzene; Diterpenes; Drug Eruptions; Hyperplasia; Indicators and Reagents; Interleukin-17; Interleukin-23; Lactones; Male; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Ornithine Decarboxylase; Peroxidase; Protein Kinase Inhibitors; Psoriasis; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2010 |
Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication.
Topics: Anti-HIV Agents; Antiviral Agents; Chikungunya virus; Diterpenes; DNA Replication; Esters; Euphorbiaceae; HIV Infections; HIV-1; HIV-2; Molecular Structure; Phorbol Esters; Tetradecanoylphorbol Acetate; Virus Replication | 2015 |
Can a 12-gene expression signature predict the cell transforming potential of tumor promoting agents in Bhas 42 cells?
Topics: Animals; BALB 3T3 Cells; Butylated Hydroxyanisole; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cholic Acid; Mice; Quercetin; Reproducibility of Results; Tetradecanoylphorbol Acetate; Transcriptome | 2023 |