tetradecanoylphorbol acetate has been researched along with methylnitronitrosoguanidine in 93 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 55 (59.14) | 18.7374 |
1990's | 25 (26.88) | 18.2507 |
2000's | 8 (8.60) | 29.6817 |
2010's | 5 (5.38) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Gunther, GR; Jamieson, JD | 1 |
Evans, FJ; Soper, CJ | 1 |
Bates, JR; Bruegge, WF; Colburn, NH; Gray, RH; Kelsey, WH; Rossen, JD; Shimada, T | 1 |
Hakura, A; Inoue, H; Inoue, M; Sasagawa, T; Tanizawa, O; Yutsudo, M | 1 |
Glick, A; Greenhalgh, D; Hennings, H; Morgan, D; Welty, D; Yuspa, SH | 1 |
Bianchi, AB; Conti, CJ; Fischer, SM; Gimenez-Conti, IB; Reiners, JJ; Slaga, TJ | 1 |
Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
Aldaz, CM; Chiba, M; Conti, CJ; Klein-Szanto, AJ | 1 |
Kawamura, K; Maruyama, K; Mochizuki, S; Tamayama, C | 1 |
Hayashi, Y; Kakimoto, K; Miyakawa, Y; Sato, SI; Takahashi, M | 1 |
Hashiba, H; Hashimoto, Y; Kuroki, T; Nose, K; Tajima, O | 1 |
Earp, HS; Grisham, JW; Raymond, VW | 1 |
Waldstein, EA | 1 |
Kominami, R | 1 |
Kuratomi, Y; Kuwano, M; Masumi, S; Ono, M; Yasutake, C | 1 |
Aldaz, CM; Conti, CJ; Miller, DR; Rotstein, J; Slaga, TJ; Viaje, A | 1 |
DiGiovanni, J; Naito, M | 1 |
Akhurst, R; Bailleul, B; Balmain, A; Brown, K; Fee, F; Ramsden, M | 1 |
Miller, DR; Morris, RJ; O'Connell, JF; Patskan, GP; Slaga, TJ; Tacker, K; Viaje, AV | 1 |
Eastin, WC | 1 |
Steele, VE | 1 |
Barrett, JC; Gray, T; Nelson, K; Nettesheim, P; Tanaka, N | 1 |
Sakai, A; Sato, M | 1 |
Bentley, KS; Fatteh, MV; Grisham, JW; Lee, LW; Smith, GJ | 1 |
Hoijer, J; Khoobyarian, N; Marczynska, B; Nelson, RL; Spragia, L; Wilson, W | 1 |
Kaufman, DG; Nelson, KG; Siegfried, JM | 1 |
Digiovanni, DM; Fries, JW; Klein-Szanto, AJ; O'Connell, JF; Slaga, TJ | 1 |
Hennings, H; Lichti, U; Michael, D; Yuspa, SH | 1 |
Delhanty, JD; Rider, SH | 1 |
Abernethy, DJ; Boreiko, CJ; Rickert, DE; Stedman, DB | 1 |
Hiwasa, T; Sakiyama, S; Tanigawara, C | 1 |
Slaga, TJ | 1 |
Gragtmans, NJ; Mitchel, RE; Morrison, DP | 1 |
Chenicek, KJ; DiGiovanni, J; Naito, M; Naito, Y | 1 |
Bowden, GT; Jaffe, DR; Williamson, JF | 1 |
Chouroulinkov, I; Lasne, C; Lu, YP | 1 |
Birt, DF; Bresnick, E; Tibbels, MG; Walker, B | 1 |
Abernethy, DJ; Boreiko, CJ; Dorman, BH; Sanchez, JH | 1 |
Abernethy, DJ; Boreiko, CJ; Sanchez, JH | 1 |
Aldaz, CM; Conti, CJ; Miller, DR; Slaga, TJ; Viaje, A | 1 |
DiPaolo, JA; Doniger, J; Evans, CH; Popescu, NC | 1 |
Abernethy, DJ; Boreiko, CJ; Greenlee, WF; Huband, JC | 1 |
Cerutti, P; Poirier, G; Singh, N | 1 |
Boreiko, CJ | 1 |
Abernethy, DJ; Boreiko, CJ; Huband, JC | 1 |
Bruce, SA; Horng, CB; Ts'o, PO | 1 |
Kaufman, DG; Siegfried, JM | 1 |
Pai, SB; Steele, VE; Topping, DC | 1 |
Decina, PC; Diamond, L; DiGiovanni, J; Prichett, WP | 1 |
Barrett, JC; Gray, TE; Mass, MJ; Nettesheim, P; Steele, VE | 1 |
Beeman, DK; Nettesheim, P; Steele, VE | 1 |
Dewdney, RS; Soper, CJ | 1 |
Gentil, A; Kinsella, A; Renault, G | 1 |
Gainer, HS; Kinsella, AR | 2 |
Abernethy, DJ; Boreiko, CJ; Frazelle, JH; Ragan, DL | 1 |
Barrett, JC; Gray, T; Sisskin, EE | 1 |
Abernethy, DJ; Boreiko, CJ; Frazelle, JH | 1 |
Nettesheim, P; Steele, V; Vanderlaan, M | 1 |
Kinsella, AR; Radman, M | 1 |
DiPaolo, JA; Doniger, JN; Evans, CH; Popescu, NC | 1 |
Hennings, H; Lichti, U; Morgan, D; Yuspa, SH | 1 |
Gentil, A; Margot, A; Renault, G | 1 |
Marchok, AC; Nettesheim, P; Steele, VE | 1 |
Arnstein, P; Huebner, RJ; Rhim, JS | 1 |
Gruener, N; Lockwood, MP | 1 |
Blessing, M; Hogan, BL; King, LE; Nanney, LB | 1 |
Rawson, TY; Showalter, SD; Srivastava, DK; Wilson, SH | 1 |
Tsuchiya, T; Umeda, M | 2 |
Balmain, A; Bremner, R; Kemp, CJ | 1 |
Colacci, A; Da Vià, C; Grilli, S; Horn, W; Manzini, E; Perocco, P; Silingardi, P; Vaccari, M | 1 |
Marquardt, H; Wölfle, D | 1 |
Gilliard, G; Megosh, LC; O'Brien, TG; Soler, AP | 1 |
Albanell, J; Allopenna, J; Dmitrovsky, E; Maerz, W; Martin, P; Moore, MA; Nason-Burchenal, K | 1 |
Kaneko, T; Miyazaki, K; Moriyama, K; Okubo, T; Sakamoto, Y; Shoji, A; Tsuchiya, T; Umeda, M | 1 |
Ishino, K; Nose, K; Shibanuma, M | 1 |
Ablett, E; Dannoy, PA; Parsons, PG; Pedley, J; Sturm, RA | 1 |
Hiranuma, H; Jikko, A; Maeda, T | 1 |
Klein-Szanto, A; Zhang, S | 1 |
Cho, MH; Fang, MZ; Kim, DY; Lee, HW | 1 |
Wölfle, D | 1 |
Ao, L; Cao, J; Huang, MH; Liu, JY; Wu, YZ; Yang, MS; Zeng, ZX; Zhang, YQ | 1 |
Abdel-Fattah, R; Glick, A; Hennings, H; Maiberger, P; Rehman, I | 1 |
Furuya, T; Inomata, K; Kawauchi, S; Oga, A; Sasaki, K | 1 |
Dai, C; Lindquist, S; Rogers, AB; Whitesell, L | 1 |
Guo, QN; Li, Y; Meng, G | 1 |
Bebenek, IG; Cochran, AJ; Gonzalez, FJ; Hankinson, O; Hodge-Bell, KC; Huerta-Yepez, S; Jaiswal, AK; Shi, S; Whitekus, MJ; Yim, SH; Yoon, DY; Zhang, R | 1 |
Chang, Y; Chen, JY; Fang, CY; Hsu, TY; Huang, SY; Takada, K; Tsai, CH | 1 |
Lee, J; Lim, KT | 1 |
Chang, Y; Chen, JY; Chou, SP; Fang, CY; Hsu, HY; Huang, SY; Takada, K; Tsai, CH; Wu, CC | 1 |
Franco, R; Hernández-Franco, P; Rojas, E; Silva, M; Valverde, M | 1 |
Li, Y; Liu, X; Lu, Y; Pei, B; Shen, W; Sun, D; Wang, X; Xiu, L; Xu, J; Yue, X; Zhang, X | 1 |
6 review(s) available for tetradecanoylphorbol acetate and methylnitronitrosoguanidine
Article | Year |
---|---|
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
Genetic background and development of skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Disease Susceptibility; Guinea Pigs; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Phorbol Esters; Rats; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1989 |
The action of oncogenes and growth factors in tumour initiation and promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Gene Expression Regulation; Genes, ras; Methylnitronitrosoguanidine; Mice; Mutation; Oncogenes; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1989 |
Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Disease Models, Animal; Drug Evaluation, Preclinical; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
Chromosomal events in carcinogenic initiation and promotion: implications for carcinogenicity testing and cancer prevention strategies.
Topics: Animals; Carcinogens; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Epistasis, Genetic; Genetic Diseases, Inborn; Humans; Methylnitronitrosoguanidine; Mutation; Skin; Tetradecanoylphorbol Acetate; Thioguanine; Time Factors | 1980 |
87 other study(ies) available for tetradecanoylphorbol acetate and methylnitronitrosoguanidine
Article | Year |
---|---|
Increased intracellular cyclic GMP does not correlate with protein discharge from pancreatic acinar cells.
Topics: Animals; Ascorbic Acid; Cyclic GMP; Dehydroascorbic Acid; Guinea Pigs; Hydroxylamines; Methylnitronitrosoguanidine; Methylnitrosourea; Nitroprusside; Pancreas; Proteins; Sodium Nitrite; Tetradecanoylphorbol Acetate | 1979 |
Investigations into the mode of action of the cocarcinogen 12-O-tetradecanoyl-phorbol-13-acetate using auxotrophic bacteria.
Topics: 4-Nitroquinoline-1-oxide; Cell Survival; DNA Repair; Methylnitronitrosoguanidine; Mutation; Phorbols; Salmonella typhimurium; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1977 |
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells.
Topics: Agar; Animals; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transplantation, Isogeneic | 1978 |
Induction of uterine cervical neoplasias in mice by human papillomavirus type 16 E6/E7 genes.
Topics: Animals; DNA, Viral; Female; Genes, Viral; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Nude; Papillomaviridae; Retroviridae Infections; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Transfection; Tumor Virus Infections; Uterine Cervical Neoplasms; Vagina; Vaginal Smears | 1992 |
Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells.
Topics: Animals; Animals, Newborn; Base Sequence; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Epidermal Cells; Epidermis; Genes, ras; Keratinocytes; Keratins; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Genes, ras; Keratins; Methylnitronitrosoguanidine; Mice; Mutation; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1992 |
Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; gamma-Glutamyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Autonomous growth of human T-lymphotropic virus type I infected human lymphocytes treated with N-methyl-N'-nitro-N-nitrosoguanidine and ultraviolet rays.
Topics: Cell Division; Cell Transformation, Viral; Cells, Cultured; Chromosomes; Combined Modality Therapy; DNA, Viral; Female; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Karyotyping; Lymphocytes; Male; Methylnitronitrosoguanidine; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1991 |
Induction of cutaneous mast cell tumors by N-methyl-N'-nitro-N-nitrosoguanidine followed by TPA in female mice of 4 out of 5 strains tested.
Topics: Animals; Cell Aggregation; Cocarcinogenesis; Female; Mast Cells; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1990 |
Elevated expression of secondary, but not early, responding genes to phorbol ester tumor promoters in papillomas and carcinomas of mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinogens; Carcinoma; Female; Gene Expression; Metallothionein; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Osteopontin; Papilloma; Proto-Oncogene Proteins; RNA, Messenger; Sialoglycoproteins; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tubulin; Urokinase-Type Plasminogen Activator | 1990 |
Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line.
Topics: Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Gene Expression; In Vitro Techniques; Methylnitronitrosoguanidine; Precipitin Tests; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1990 |
Effect of O6-methylguanine-DNA methyltransferase gene activity on repair in human cells transformed by a regulatable ada gene.
Topics: Cell Line; Dexamethasone; DNA Repair; Gene Expression Regulation, Enzymologic; Genes; HeLa Cells; Humans; Kinetics; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Tetradecanoylphorbol Acetate; Transfection | 1990 |
A sensitive assay for detecting mutations resulting from unequal homologous recombination without phenotypic selection.
Topics: Animals; Blotting, Southern; DNA, Ribosomal; Drug Resistance; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mitosis; Mutagenicity Tests; Phenotype; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Selection, Genetic; Tetradecanoylphorbol Acetate | 1990 |
Effect of 5-azacytidine on malignant transformation of a mutant derived from the mouse BALB/c 3T3 cell line resistant to transformation by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Metallothionein; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1987 |
Induction of terminal differentiation-resistant epidermal cells in mouse skin and in papillomas by different initiators during two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Epidermal Cells; Female; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Developing design standards for dermal initiation/promotion screening studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogenicity Tests; Female; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Research Design; Skin; Tetradecanoylphorbol Acetate | 1989 |
Multistage-promotion and carcinogenesis studies in rat tracheal epithelial cells in culture.
Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Keratins; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1985 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin enhancement of N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation of rat tracheal epithelial cells in culture.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dioxins; Dose-Response Relationship, Drug; Epithelium; Male; Methylnitronitrosoguanidine; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutagens; Tetradecanoylphorbol Acetate | 1989 |
Induction of foci of morphologically transformed cells in synchronized populations of 10T1/2 cells by N-methyl-N'-nitro-N-nitrosoguanidine and the effect of spontaneous transformation on calculated transformation frequency.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Mutation; Proto-Oncogenes; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1988 |
Chromosomal and c-K-ras oncogene alterations induced by a chemical carcinogen and phorbol ester in skin fibroblasts of individuals with familial polyposis coli.
Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Cell Division; Cells, Cultured; Child; Chromosome Aberrations; Deoxyribonuclease EcoRI; Fibroblasts; Genes, ras; Humans; Methylnitronitrosoguanidine; Ploidies; Skin; Tetradecanoylphorbol Acetate | 1988 |
Promotion-like enhancement of transformed phenotypes in human endometrial stromal cells.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Diethylstilbestrol; Endometrium; Female; gamma-Glutamyltransferase; Humans; L-Lactate Dehydrogenase; Methylnitronitrosoguanidine; Phenotype; Tetradecanoylphorbol Acetate | 1985 |
Malignant progression of mouse skin papillomas treated with ethylnitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine, or 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ethylnitrosourea; Female; gamma-Glutamyltransferase; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Response of carcinogen-altered mouse epidermal cells to phorbol ester tumor promoters and calcium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cocarcinogenesis; Colony-Forming Units Assay; Drug Interactions; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate; Transglutaminases | 1987 |
Transformation studies on human fibroblasts from familial polyposis coli patients and normal donors.
Topics: Adenomatous Polyposis Coli; Cell Division; Cell Transformation, Neoplastic; Fibroblasts; Humans; Kinetics; Methylnitronitrosoguanidine; Multiple Endocrine Neoplasia; Neoplasms; Skin; Tetradecanoylphorbol Acetate | 1988 |
Effect of growth state, tumor promoters, and transformation upon intercellular communication between C3H/10T1/2 murine fibroblasts.
Topics: Animals; Carcinogens; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Isoquinolines; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1989 |
Defects of cyclic adenosine 3':5'-monophosphate-dependent protein kinases in initiated clones derived from BALB/c 3T3 mouse fibroblasts.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Ethyl Methanesulfonate; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Protein Kinases; Tetradecanoylphorbol Acetate | 1987 |
The influence of a hyperthermia treatment on chemically induced tumor initiation and progression in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; DNA Repair; Female; Glutathione; Hyperthermia, Induced; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Susceptibility to phorbol ester skin tumor promotion in (C57BL/6 x DBA/2) F1 mice is inherited as an incomplete dominant trait: evidence for multi-locus involvement.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Genes, Dominant; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Ionizing radiation enhances malignant progression of mouse skin tumors.
Topics: Acetone; Animals; Carcinoma; Cocarcinogenesis; Female; Methylnitronitrosoguanidine; Mice; Neoplasms, Radiation-Induced; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Use of an orthogonal design method to study two-stage chemical carcinogenesis in BALB/3T3 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fetal Blood; Methylnitronitrosoguanidine; Mice; Statistics as Topic; Tetradecanoylphorbol Acetate | 1986 |
Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Chamomile; Female; Flavonoids; Indoles; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Mice, Inbred Strains; Mutagens; Mutation; Neoplasms, Experimental; Oils, Volatile; Ornithine Decarboxylase; Plant Extracts; Plants, Medicinal; Skin; Tetradecanoylphorbol Acetate | 1986 |
Effect of mouse skin tumor promoters upon [3H]uridine exchange and focus formation in cultures of C3H/10T1/2 mouse fibroblasts.
Topics: Animals; Carcinogens; Cells, Cultured; Dimethyl Sulfoxide; Diterpenes; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Polychlorinated Dibenzodioxins; Pregnancy; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Uridine | 1986 |
Reversible expression of morphological transformation in C3H/10T1/2 mouse embryo cultures exposed to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Phenotype; Tetradecanoylphorbol Acetate | 1986 |
Terminal differentiation-resistant epidermal cells in mice undergoing two-stage carcinogenesis.
Topics: Animals; Cell Differentiation; Cells, Cultured; Female; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Precancerous Conditions; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Enhancement and inhibition of transformation of Syrian hamster embryo cells.
Topics: Animals; Asbestos; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Female; Lymphokines; Mesocricetus; Methylnitronitrosoguanidine; Polycyclic Compounds; Sulfur Dioxide; Tetradecanoylphorbol Acetate | 1985 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) promotes the transformation of C3H/10T1/2 cells.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Dimethyl Sulfoxide; Dioxins; Dose-Response Relationship, Drug; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate | 1985 |
Tumor promoter phorbol-12-myristate-13-acetate induces poly(ADP)-ribosylation in fibroblasts.
Topics: Animals; Antioxidants; Cells, Cultured; DNA; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nucleoside Diphosphate Sugars; Oxygen; Phorbols; Poly Adenosine Diphosphate Ribose; Tetradecanoylphorbol Acetate | 1985 |
Mechanistic aspects of initiation and promotion in C3H/10T1/2 cells.
Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Embryo, Mammalian; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1985 |
Potential role of treatment artifact in the effect of cell density upon frequencies of C3H/10T1/2 cell transformation.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Research Design; Tetradecanoylphorbol Acetate | 1985 |
A comparative study on neoplastic transformation of human and Syrian hamster cells.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Female; Fetus; Fibroblasts; Fibrosarcoma; Griseofulvin; Humans; Kinetics; Mesocricetus; Methylnitronitrosoguanidine; Pregnancy; Species Specificity; Tetradecanoylphorbol Acetate | 1985 |
Enhancement by TPA of phenotypes associated with transformation in carcinogen-treated human cells: evidence for a selective mechanism.
Topics: Cell Aggregation; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Culture Media; Female; gamma-Glutamyltransferase; Humans; Methylnitronitrosoguanidine; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Uterus | 1983 |
Tumor promotion studies in rat tracheal epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cells, Cultured; Cocarcinogenesis; Epithelium; Methylnitronitrosoguanidine; Neoplasms, Experimental; Organ Culture Techniques; Rats; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1983 |
DBA/2 mice are as sensitive as SENCAR mice to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA; Female; Methylnitronitrosoguanidine; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Phorbols; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1984 |
Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Humans; Methylnitronitrosoguanidine; Mice; Rats; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1984 |
Enhanced induction of the anchorage-independent phenotype in initiated rat tracheal epithelial cell cultures by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Adhesion; Cell Division; Cells, Cultured; Epithelial Cells; Epithelium; Kinetics; Methylnitronitrosoguanidine; Phenotype; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea | 1984 |
A mutagenesis-enhancing activity of 12-O-tetradecanoylphorbol 13-acetate detected in Chinese hamster ovary cells.
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitronitrosoguanidine; Mutation; Ovary; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1984 |
Induction of sister chromatid exchanges in split-dose and cell-fusion experiments.
Topics: Animals; Cell Fusion; Cell Line; Cricetinae; Cricetulus; Fibroblasts; Hybrid Cells; Lung; Male; Methylnitronitrosoguanidine; Radiation Dosage; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1984 |
Analysis of spontaneous, carcinogen-induced and promoter-induced chromosomal instability in patients with hereditary retinoblastoma.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Deletion; Eye Neoplasms; Humans; Methylnitronitrosoguanidine; Ploidies; Retinoblastoma; Sister Chromatid Exchange; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
In vitro studies of the possible mechanisms whereby tumour promoters mediate their responses.
Topics: Carcinogens; Cell Movement; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Colonic Neoplasms; Eye Neoplasms; Fibroblasts; Humans; Methylnitronitrosoguanidine; Mutation; Retinoblastoma; Skin; Tetradecanoylphorbol Acetate | 1983 |
Initiation of C3H/10T1/2 cell transformation by N-methyl-N'-nitro-N-nitrosoguanidine and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1982 |
Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with 12-O-tetra-decanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Hyperplasia; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Phorbols; Rats; Rats, Inbred F344; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Factors influencing the promotion of transformation in chemically-initiated C3H/10T1/2 Cl 8 mouse embryo fibroblasts.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Female; Fibroblasts; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Increased DNA content as an early marker of transformation in carcinogen-exposed rat tracheal cell cultures.
Topics: Aneuploidy; Animals; Cell Transformation, Neoplastic; DNA; Interphase; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Trachea | 1983 |
Regulation of mammalian cell transformation.
Topics: Animals; Antipain; Caffeine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Cricetinae; DNA Repair; Lymphokines; Methylnitronitrosoguanidine; Mutation; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays; X-Rays | 1982 |
Chemical carcinogenesis studies in mouse epidermal cell cultures.
Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Environmental Exposure; Enzyme Induction; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
The effect of the tumour promoter 12-O-tetradecanoyl-phorbol-13-acetate (TPA) on UV- and MNNG-induced sister chromatid exchanges in mammalian cells.
Topics: Animals; Cricetinae; Crossing Over, Genetic; Dose-Response Relationship, Drug; Methylnitronitrosoguanidine; Phorbols; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1980 |
Enhancement of carcinogenesis in cultured respiratory tract epithelium by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms | 1980 |
Chemical transformation of cultured skin fibroblasts from humans genetically predisposed to cancer.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Gardner Syndrome; Humans; Methylnitronitrosoguanidine; Skin; Tetradecanoylphorbol Acetate | 1981 |
Mutagenic activity in drinking water.
Topics: Acetone; Animals; Benzopyrenes; Cell Line; Cricetinae; Cricetulus; Lung; Methylnitronitrosoguanidine; Microsomes, Liver; Mutagens; Mutation; Rats; Tetradecanoylphorbol Acetate; Water Supply | 1980 |
Chemical skin carcinogenesis is prevented in mice by the induced expression of a TGF-beta related transgene.
Topics: Animals; Bone Morphogenetic Proteins; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Epidermis; Methylnitronitrosoguanidine; Mice; Mice, Transgenic; Papilloma; Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1995 |
Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.
Topics: Alkylating Agents; Amino Acid Sequence; Animals; Antibodies, Monoclonal; CHO Cells; Cricetinae; DNA Damage; DNA Polymerase I; DNA Repair; Drug Antagonism; Epitope Mapping; Immunoblotting; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Molecular Sequence Data; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 1995 |
Improvement in the efficiency of the in vitro transformation assay method using BALB/3T3 A31-1-1 cells.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Culture Media; Dimethylnitrosamine; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1995 |
Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Chromosome Deletion; Genes, ras; Methylnitronitrosoguanidine; Mice; Mutation; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trisomy | 1994 |
Enhancement of BALB/c 3T3 cells transformation by 1,2-dibromoethane promoting effect.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethane; Ethylene Dibromide; Hydrocarbons, Chlorinated; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate | 1996 |
Antioxidants inhibit the enhancement of malignant cell transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Drug Interactions; Enzyme Inhibitors; Fibroblasts; Isoquinolines; Mannitol; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Piperazines; Polychlorinated Dibenzodioxins; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vitamin E | 1996 |
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Animals, Newborn; Benzo(a)pyrene; Hair Follicle; Immunohistochemistry; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Putrescine; Skin; Skin Neoplasms; Spermidine; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Relationship between exposure to TPA and appearance of transformed cells in MNNG-initiated transformation of BALB/c 3T3 cells.
Topics: 3T3 Cells; Animals; Carcinogens; Cell Count; Cell Line, Transformed; Cell Transformation, Neoplastic; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.
Topics: Antineoplastic Agents; Binding Sites; Blotting, Western; Carcinogens; Cell Differentiation; Cell Division; Cell Nucleus; Cholecalciferol; Clone Cells; DNA, Neoplasm; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Methylnitronitrosoguanidine; Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Telomerase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1997 |
Inhibition of tumor promoter activity toward mouse fibroblasts and their in vitro transformation by tissue inhibitor of metalloproteinases-1 (TIMP-1).
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Communication; Cell Transformation, Neoplastic; Fibroblasts; Gap Junctions; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Protease Inhibitors; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 1997 |
Increase in telomere sequence-binding activity in normal human fibroblasts in senescence or in cells treated with phorbol ester or N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Carcinogens; Cells, Cultured; Cellular Senescence; DNA; DNA Damage; DNA Repair; Fibroblasts; Humans; Methylnitronitrosoguanidine; Nuclear Proteins; Telomere; Tetradecanoylphorbol Acetate | 1998 |
UVB-specific regulation of gene expression in human melanocytic cells: cell cycle effects and implication in the generation of melanoma.
Topics: Antineoplastic Agents; beta-Galactosidase; Cell Cycle; Cisplatin; Demecolcine; Genes, fos; Genes, p53; HeLa Cells; HIV Long Terminal Repeat; Humans; Hydroxyurea; Inosine; Melanocytes; Melanoma; Methylnitronitrosoguanidine; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Organophosphorus Compounds; Proto-Oncogene Proteins c-fos; Recombinant Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Ultraviolet Rays | 1998 |
Differential expression of the splicing regulatory factor genes during two-step chemical transformation in a BALB/3T3-derived cell line, MT-5.
Topics: 3T3 Cells; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Nuclear Proteins; RNA Splicing; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Tetradecanoylphorbol Acetate | 1999 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium.
Topics: 3T3 Cells; Animals; Cadmium; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; In Vitro Techniques; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nitrobenzenes; Polychlorinated Dibenzodioxins; Sulfonamides; Tetradecanoylphorbol Acetate | 2003 |
[Gene expression profiles in early stage of BALB/c 3T3 cells' transformation promoted with 12-O-tetradecanoylphorbol-13-acetate].
Topics: Animals; Apoptosis; BALB 3T3 Cells; Cell Cycle; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Flow Cytometry; Gene Expression; Gene Expression Profiling; Methylnitronitrosoguanidine; Mice; Oligonucleotide Array Sequence Analysis; Tetradecanoylphorbol Acetate | 2005 |
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methylnitronitrosoguanidine; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Global genomic changes induced by two-stage carcinogen exposure are precancerous alterations in non-transformed human liver epithelial THLE-3 cells.
Topics: Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 17; DNA; DNA Damage; G1 Phase; Gene Expression Regulation, Neoplastic; Genome, Human; Genotype; Humans; In Situ Hybridization, Fluorescence; Laser Scanning Cytometry; Liver; Methylnitronitrosoguanidine; Neoplasms; Nucleic Acid Hybridization; Phenotype; Ploidies; Resting Phase, Cell Cycle; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Glucose; Heat Shock Transcription Factors; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; ras Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53 | 2007 |
Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.
Topics: Bone Neoplasms; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Methylation; Gene Expression Regulation, Neoplastic; Genomic Imprinting; Humans; Methylnitronitrosoguanidine; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteosarcoma; Tetradecanoylphorbol Acetate | 2008 |
The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Epidermis; Gene Deletion; Methylnitronitrosoguanidine; Mice; Receptors, Aryl Hydrocarbon; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
N-methyl-N'-nitro-N-nitrosoguanidine induces and cooperates with 12-O-tetradecanoylphorbol-1,3-acetate/sodium butyrate to enhance Epstein-Barr virus reactivation and genome instability in nasopharyngeal carcinoma cells.
Topics: Butyric Acid; Cell Line, Tumor; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Drug Synergism; Genomic Instability; Herpesvirus 4, Human; Humans; Immediate-Early Proteins; Methylnitronitrosoguanidine; Micronucleus Tests; Nasopharyngeal Neoplasms; Phorbol Esters; Promoter Regions, Genetic; Reactive Oxygen Species; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Activation; Virus Activation | 2010 |
Modulatory effect of phytoglycoprotein (38 kDa) on cyclin D1/CDK4 in BNL CL.2 cells induced by N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Animals; Carcinogens; Cell Line; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor Proteins; Extracellular Signal-Regulated MAP Kinases; Fruit; Glycoproteins; Methylnitronitrosoguanidine; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Plant Proteins; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Styrax; Tetradecanoylphorbol Acetate | 2012 |
The synergistic effect of chemical carcinogens enhances Epstein-Barr virus reactivation and tumor progression of nasopharyngeal carcinoma cells.
Topics: Animals; Butyrates; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Viral; Disease Progression; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome, Human; Genomic Instability; Herpesvirus 4, Human; Humans; Methylnitronitrosoguanidine; Mice; Mice, SCID; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Tetradecanoylphorbol Acetate; Virus Activation | 2012 |
Lead facilitates foci formation in a Balb/c-3T3 two-step cell transformation model: role of Ape1 function.
Topics: Animals; BALB 3T3 Cells; Carcinogens, Environmental; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Comet Assay; DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Expression; Humans; Lead; Methylnitronitrosoguanidine; Mice; Models, Biological; Tetradecanoylphorbol Acetate | 2018 |
Xiao Tan He Wei Decoction reverses MNNG-induced precancerous lesions of gastric carcinoma in vivo and vitro: Regulation of apoptosis through NF-κB pathway.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Disease Models, Animal; Drugs, Chinese Herbal; Epithelial-Mesenchymal Transition; Humans; Hyperplasia; Methylnitronitrosoguanidine; NF-kappa B; Precancerous Conditions; Rats, Wistar; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 2018 |