Page last updated: 2024-08-23

tetradecanoylphorbol acetate and methotrexate

tetradecanoylphorbol acetate has been researched along with methotrexate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199012 (42.86)18.7374
1990's8 (28.57)18.2507
2000's8 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Cardinale, I; Sehgal, PB; Tamm, I1
Hildebrand, G; Leserman, L; Suzuki, H; Zelphati, O1
Fox, M; Kinsella, AR; Szallasi, A1
Fox, M; Kinsella, AR1
Cheng, YC; Ferguson, PJ1
Comerford, M; Halprin, KM; Taylor, JR1
Barsoum, J; Varshavsky, A1
Barsoum, J; Roninson, I; Snapka, R; Varshavsky, A1
Bojan, F; Fox, M; Kinsella, AR2
Brown, PC; Schimke, RT; Tlsty, TD1
Grzelakowska-Sztabert, B1
Varshavsky, A1
Kinzel, V; Richards, J; Stöhr, M1
Adler, GK; Arbiser, JL; Arbiser, ZK; Majzoub, JA; Martinez, C; Rosen, LB1
Jahan, N; Mitsuya, H; O'Brien, MC; Ueno, T; Zajac-Kaye, M1
Fahrig, R; Steinkamp-Zucht, A1
Coffey, D; Cronstein, BN; Fisher, R; Lahita, RG; Merrill, JT; Salmon, J; Schreibman, D; Shen, C; Zakharenko, O1
Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Okuda, A; Sawada, M; Usami, I; Watanabe, K1
Hashimoto, Y; Inui, K; Okuda, M; Takami, K; Uwai, Y1
Masereeuw, R; Miller, DS; Russel, FG; Terlouw, SA1
Alemany, C; Ciudad, CJ; Nicolás, M; Noé, V1
Denker, HW; Hohn, HP1
Hirade, K; Ishisaki, A; Kanno, Y; Katagiri, Y; Kozawa, O; Nakajima, K; Shimizu, K; Tokuda, H; Yoshida, M1
Fricker, G; Miller, DS; Reichel, V1
Chang, CH; Chang, TJ; Chang, YJ; Ho, TY; Hsiang, CY; Lee, TW; Lin, WJ; Yu, CY1

Reviews

2 review(s) available for tetradecanoylphorbol acetate and methotrexate

ArticleYear
Acquisition and loss of amplified genes: dramatic effects of hormones, tumor promoters and cytotoxic drugs.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Antineoplastic Agents; Base Sequence; Carcinogens; DNA; DNA Replication; Drug Resistance; Gene Amplification; Hormones; Humans; Hydroxyurea; Insulin; Methotrexate; Mice; Mitogens; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1983
Experimental modulation of cell-cell adhesion, invasiveness and differentiation in trophoblast cells.
    Cells, tissues, organs, 2002, Volume: 172, Issue:3

    Topics: Antimetabolites, Antineoplastic; Bucladesine; Cell Adhesion; Cell Communication; Cell Differentiation; Cell Line; Chorionic Gonadotropin; Endometrium; Female; Humans; Matrix Metalloproteinase 2; Methotrexate; Pregnancy; Tetradecanoylphorbol Acetate; Tretinoin; Trophoblasts

2002

Other Studies

26 other study(ies) available for tetradecanoylphorbol acetate and methotrexate

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Interleukin-6 and 12-O-tetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells.
    Cytokine, 1991, Volume: 3, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Antibodies, Monoclonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Line; Cell Movement; Cytokines; DNA Replication; Drug Synergism; Female; Floxuridine; Growth Substances; Humans; Interleukin-6; Methotrexate; Protein Kinase C; Recombinant Proteins; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate

1991
CD4 and CD7 molecules as targets for drug delivery from antibody bearing liposomes.
    Experimental cell research, 1991, Volume: 193, Issue:1

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; CD4 Antigens; Drug Carriers; Endocytosis; HeLa Cells; Humans; Liposomes; Methotrexate; Staphylococcal Protein A; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection

1991
TPA enhancement of the recovery of methotrexate and N-phosphonacetyl L-aspartate resistant mouse 3T6 cell clones is associated with transient alterations of cell cycle progression.
    International journal of cancer, 1988, Jul-15, Volume: 42, Issue:1

    Topics: Animals; Aspartic Acid; Cell Cycle; Cell Line; Cell Survival; Cricetinae; Drug Interactions; Drug Resistance; Interphase; Methotrexate; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Tetradecanoylphorbol Acetate

1988
Phenotypic resistance to methotrexate and N-phosphonacetyl L-aspartate is induced by treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA).
    International journal of cancer, 1988, Jul-15, Volume: 42, Issue:1

    Topics: Animals; Aspartic Acid; Cell Line; Drug Interactions; Drug Resistance; Gene Amplification; Methotrexate; Organophosphorus Compounds; Phenotype; Phosphonoacetic Acid; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1988
Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1987, Jan-15, Volume: 47, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Etoposide; Humans; Methotrexate; Mitoxantrone; Nasopharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases; Verapamil; Vincristine

1987
Control of epidermal cell proliferation in vitro.
    The British journal of dermatology, 1984, Volume: 111 Suppl 27

    Topics: Adenosine; Animals; Cell Movement; Cells, Cultured; Culture Media; Cyclic AMP; Epinephrine; Glycoproteins; Histamine; Hot Temperature; Hydroxyurea; Methotrexate; Mitosis; Prostaglandins; Skin; Swine; Tetradecanoylphorbol Acetate; Vitronectin

1984
Mitogenic hormones and tumor promoters greatly increase the incidence of colony-forming cells bearing amplified dihydrofolate reductase genes.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:17

    Topics: Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Clone Cells; Drug Resistance; Epidermal Growth Factor; Gene Amplification; Genes; Hormones; Insulin; Methotrexate; Mice; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1983
Effect of 12-O-tetradecanoylphorbol-13-acetate on selection of drug-resistant phenotypes in rodent cells.
    IARC scientific publications, 1984, Issue:56

    Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cadmium; Cell Line; Cells, Cultured; Clone Cells; Cricetinae; Cricetulus; Drug Resistance; Lung; Methotrexate; Mice; Phenotype; Phorbols; Phosphonoacetic Acid; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1984
Effect of tumor promoter 12-O-tetradecanoylphorbol-13-acetate on recovery of methotrexate-, N-(phosphonacetyl)-L-aspartate-, and cadmium-resistant colony-forming mouse and hamster cells.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Animals; Antineoplastic Agents; Aspartic Acid; Cadmium; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Drug Resistance; Kinetics; Lung; Methotrexate; Mice; Organophosphorus Compounds; Phorbols; Phosphonoacetic Acid; Tetradecanoylphorbol Acetate

1983
UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells.
    Molecular and cellular biology, 1984, Volume: 4, Issue:6

    Topics: Acetoxyacetylaminofluorene; Animals; Cells, Cultured; DNA Replication; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Genes; Kinetics; Methotrexate; Mice; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays

1984
[Cocarcinogen as a factor increasing the incidence of mutation responsible for cellular resistance to antifolates].
    Postepy biochemii, 1982, Volume: 28, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Cocarcinogenesis; Drug Resistance; Genes; Humans; Methotrexate; Mice; Mutation; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1982
Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: possible mechanisms and relevance to tumor promotion.
    Cell, 1981, Volume: 25, Issue:2

    Topics: Animals; Cell Count; Cell Division; Cell Line; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance; Gene Amplification; Methotrexate; Mice; Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase

1981
Responses of synchronized HeLa cells to the tumor-promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate as evaluated by flow cytometry.
    Cancer research, 1981, Volume: 41, Issue:1

    Topics: Cell Cycle; DNA, Neoplasm; HeLa Cells; Humans; Methotrexate; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1981
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line; Colforsin; Dexamethasone; Gene Expression Regulation, Neoplastic; Glycoprotein Hormones, alpha Subunit; Humans; Hydroxyurea; Kinetics; Liver Neoplasms; Methotrexate; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured

1994
HIV-1 expression induced by anti-cancer agents in latently HIV-1-infected ACH2 cells.
    Biochemical and biophysical research communications, 1995, Feb-27, Volume: 207, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Cytarabine; DNA; Fluorouracil; HIV-1; Methotrexate; Methylation; Molecular Sequence Data; NF-kappa B; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Vinblastine

1995
Induction or suppression of SV40 amplification by genotoxic carcinogens, non-genotoxic carcinogens or tumor promoters.
    Mutation research, 1996, Sep-23, Volume: 356, Issue:2

    Topics: Acetamides; Acetone; Anthracenes; Carcinogens; Cell Line, Transformed; Coumarins; Deoxyuridine; Dimethylformamide; Diterpenes; DNA, Viral; Mercaptopurine; Methotrexate; Mutagens; Nitroquinolines; Nucleic Acid Hybridization; Simian virus 40; Terpenes; Testosterone; Tetradecanoylphorbol Acetate; Thioacetamide; Virus Replication

1996
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis.
    Arthritis and rheumatism, 1997, Volume: 40, Issue:7

    Topics: Adenosine; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Humans; Methotrexate; Monocytes; Receptors, Purinergic P1; Rheumatoid Nodule; Tetradecanoylphorbol Acetate; Theobromine; Xanthines

1997
Inhibition of superoxide production and chemotaxis by methotrexate in neutrophils primed by TNF-alpha or LPS.
    European journal of haematology, 1997, Volume: 59, Issue:3

    Topics: Cells, Cultured; Chemotaxis, Leukocyte; Cytochrome c Group; Guanosine; Humans; Hypoxanthine; Interleukin-8; Lipopolysaccharides; Methotrexate; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1997
Functional characterization of the rat multispecific organic anion transporter OAT1 mediating basolateral uptake of anionic drugs in the kidney.
    FEBS letters, 1998, Nov-06, Volume: 438, Issue:3

    Topics: Animals; Anion Transport Proteins; Anions; Biological Transport; Carrier Proteins; Cell Membrane; Dicarboxylic Acids; Diterpenes; DNA Primers; DNA, Complementary; Female; Folic Acid; Glutarates; Kidney; Kinetics; Methotrexate; Oocytes; p-Aminohippuric Acid; Phorbol Esters; Probenecid; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis

1998
Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: effect on drug efflux.
    Molecular pharmacology, 2001, Volume: 59, Issue:6

    Topics: Animals; Biological Transport; Calcium; Endothelins; Energy Metabolism; Fluoresceins; Kidney Tubules, Proximal; Killifishes; Methotrexate; Signal Transduction; Tetradecanoylphorbol Acetate

2001
Sp1 involvement in the 4beta-phorbol 12-myristate 13-acetate (TPA)-mediated increase in resistance to methotrexate in Chinese hamster ovary cells.
    European journal of biochemistry, 2001, Volume: 268, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Drug Resistance; Enzyme Activation; Methotrexate; Plicamycin; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Tetrahydrofolate Dehydrogenase; Transfection; Up-Regulation

2001
Methotrexate suppresses inflammatory agonist induced interleukin 6 synthesis in osteoblasts.
    The Journal of rheumatology, 2005, Volume: 32, Issue:5

    Topics: 3T3 Cells; Animals; Antirheumatic Agents; Carcinogens; Cells, Cultured; Dinoprost; Dinoprostone; Drug Interactions; Interleukin-1; Interleukin-17; Interleukin-6; Methotrexate; Mice; Osteoblasts; Prostaglandin D2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:4

    Topics: Animals; Biological Transport; Choroid Plexus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrone; Female; In Vitro Techniques; Kinetics; Leukotriene C4; Male; Meglumine; Methotrexate; Models, Biological; Organic Anion Transporters; p-Aminohippuric Acid; Potassium; Propionates; Protein Kinase C; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Squalus acanthias; Taurocholic Acid; Tetradecanoylphorbol Acetate; Xanthenes

2008
Noninvasive bioluminescent and microPET imaging for the regulation of NF-kappaB in human hepatoma-bearing mice.
    Anticancer research, 2009, Volume: 29, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinogens; Diagnostic Imaging; Female; Fluorodeoxyglucose F18; Humans; Liver Neoplasms, Experimental; Luciferases; Luminescent Measurements; Methotrexate; Mice; Mice, Nude; Mice, SCID; NF-kappa B; Positron-Emission Tomography; Radiopharmaceuticals; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2009