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tetradecanoylphorbol acetate and indolactam v

tetradecanoylphorbol acetate has been researched along with indolactam v in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's10 (43.48)18.2507
2000's6 (26.09)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, A; Kozikowski, AP; Lazo, JS; Shum, PW1
Irie, K; Nakagawa, Y; Nakamura, Y; Ohigashi, H1
Borowiak, M; Chen, S; Davidow, L; Fox, JL; Lam, K; Maehr, R; Melton, D; Osafune, K; Peng, LF; Rubin, LL; Schreiber, SL1
Benjamin, D; Kantor, RR; Norihisa, Y; Pang, Y; Young, HA1
Collier, IE; Eisen, AZ; Goldberg, GI; Grant, GA; Marmer, BL; Wilhelm, SM1
Fujiki, H; Furuya-Suguri, H; Muratake, H; Nakayasu, M; Natsume, M; Nishiwaki, S; Okabe, K; Okabe, S; Suganuma, M; Yoshizawa, S1
Harmody, D; Longley, RE1
Cela, A; Krueger, J; Leong, I1
Banga, HS; Feinstein, MB; Halenda, SP; Lau, LF; Zavoico, GB1
Akerman, KE; Heikkilä, J1
Endo, Y; Fujiki, H; Itai, A; Shudo, K1
Hagiwara, N; Irie, K; Koshimizu, K; Tokuda, H1
Endo, Y; Fujiki, H; Hasegawa, M; Hirota, M; Horiuchi, T; Nakayasu, M; Shudo, K; Suganuma, M; Yoshizawa, S1
Endo, Y; Fujiki, H; Nakayasu, M; Shudo, K; Suganuma, M; Sugimura, T; Tahira, T1
Golard, A; Role, LW; Siegelbaum, SA1
Hansen, H; Riedel, H; Shieh, HL; Zhu, J2
Brockman, JA; Hayes, SH; Lee, JS; Lowberger, LL; Silvia, WJ; Trammell, DS1
Chen, Y; Deng, J; Wu, R1
Bellingham, J; Clair, L; Rodriguez, JL; Wahlstrom, K; West, MA1
Endo, Y; Fukasawa, H; Hashimoto, Y; Shudo, K; Yamaguchi, M1
Basu, A; Huang, J; Mohanty, S1
Aschermann, L; Cao, S; Carpenter, C; Clardy, J; Neubig, RR; Raveh, A; Schultz, PJ; Sherman, DH; Sjögren, B; Tamayo-Castillo, G1

Other Studies

23 other study(ies) available for tetradecanoylphorbol acetate and indolactam v

ArticleYear
Synthesis of structural analogues of lyngbyatoxin A and their evaluation as activators of protein kinase C.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Adenosine Triphosphate; Chemical Phenomena; Chemistry; Enzyme Activation; HeLa Cells; Histones; Humans; Lyngbya Toxins; Marine Toxins; Molecular Structure; Phosphorylation; Protein Kinase C; Structure-Activity Relationship

1991
The amide hydrogen of (-)-indolactam-V and benzolactam-V8's plays a critical role in protein kinase C binding and tumor-promoting activities.
    Bioorganic & medicinal chemistry letters, 2001, Mar-12, Volume: 11, Issue:5

    Topics: Antigens, Viral; Carcinogens; Humans; Hydrogen; Indoles; Kinetics; Lactams; Magnetic Resonance Spectroscopy; Molecular Structure; Protein Binding; Protein Isoforms; Protein Kinase C; Radioligand Assay; Superoxides

2001
A small molecule that directs differentiation of human ESCs into the pancreatic lineage.
    Nature chemical biology, 2009, Volume: 5, Issue:4

    Topics: Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Line; Embryonic Stem Cells; Homeodomain Proteins; Humans; Indoles; Insulin-Secreting Cells; Lactams; Mice; Trans-Activators

2009
Interferon-gamma gene expression in human B-cell lines: induction by interleukin-2, protein kinase C activators, and possible effect of hypomethylation on gene regulation.
    Blood, 1992, Aug-01, Volume: 80, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Surface; B-Lymphocytes; Blotting, Southern; Burkitt Lymphoma; Carcinogens; Cell Line; DNA, Neoplasm; Enzyme Activation; Flow Cytometry; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Rearrangement; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains; Indoles; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-4; Interleukin-6; Lactams; Methylation; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate

1992
Mosaic structure of the secreted ECM metalloproteases and interaction of the type IV collagenases with inhibitors.
    Matrix (Stuttgart, Germany). Supplement, 1992, Volume: 1

    Topics: Amino Acid Sequence; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Viral; Collagenases; Enzyme Activation; Enzyme Induction; Extracellular Matrix Proteins; Fibroblasts; Fibrosarcoma; Glycoproteins; Humans; Indoles; Keratinocytes; Lactams; Macrophages; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Molecular Sequence Data; Monocytes; Multigene Family; Neoplasm Proteins; Phenylmercuric Acetate; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Simian virus 40; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured

1992
Pendolmycin, a new tumor promoter of the teleocidin A class on skin of CD-1 mice.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:7

    Topics: Alkaloids; Animals; Carcinogens; Enzyme Activation; Female; Indoles; Lactams; Lyngbya Toxins; Mice; Mice, Inbred Strains; Protein Kinase C; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium

1991
A rapid colorimetric microassay to detect agonists/antagonists of protein kinase C based on adherence of EL-4.IL-2 cells.
    The Journal of antibiotics, 1991, Volume: 44, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Carcinogens; Cell Adhesion; Colorimetry; Diterpenes; Dose-Response Relationship, Drug; Enzyme Activation; Indoles; Isoquinolines; Lactams; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Reproducibility of Results; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured

1991
Tigliane-type phorbols stimulate human melanocyte proliferation: potentially safer agents for melanocyte culture.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:6

    Topics: Cell Division; Cells, Cultured; Enzyme Activation; Humans; Indoles; Lactams; Melanocytes; Phorbol Esters; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1991
Synergistic release of arachidonic acid from platelets by activators of protein kinase C and Ca2+ ionophores. Evidence for the role of protein phosphorylation in the activation of phospholipase A2 and independence from the Na+/H+ exchanger.
    Biochemistry, 1989, Sep-05, Volume: 28, Issue:18

    Topics: Adenosine Triphosphate; Alkaloids; Amiloride; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Carrier Proteins; Enzyme Activation; Humans; Indoles; Ionomycin; Ionophores; Kinetics; Lactams; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases

1989
(-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells.
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Calcium; Cell Compartmentation; Cell Differentiation; Cell Membrane; Enzyme Activation; Humans; Indoles; Lactams; Neuroblastoma; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1989
[The active structure of tumor promoters].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:12

    Topics: Carcinogens; Indoles; Lactams; Lyngbya Toxins; Protein Kinase C; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1986
The metabolism of indole alkaloid tumor promoter, (-)-indolactam V, which has the fundamental structure of teleocidins, by rat liver microsomes.
    Carcinogenesis, 1987, Volume: 8, Issue:7

    Topics: Animals; Antigens, Viral; Carcinogens; In Vitro Techniques; Indoles; Lactams; Lyngbya Toxins; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium

1987
Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:6

    Topics: Animals; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indoles; Lactams; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Protein Kinase C; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1987
Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin.
    Gan, 1984, Volume: 75, Issue:10

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Enzyme Induction; Humans; Indoles; Kinetics; Lactams; Leukemia, Myeloid, Acute; Mice; Ornithine Decarboxylase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1984
Protein kinase C blocks somatostatin-induced modulation of calcium current in chick sympathetic neurons.
    Journal of neurophysiology, 1993, Volume: 70, Issue:4

    Topics: Animals; Calcium Channels; Chick Embryo; Electric Stimulation; Enzyme Activation; Ganglia, Sympathetic; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Lactams; Naphthalenes; Neurons; Polycyclic Compounds; Protein Kinase C; Receptors, Somatostatin; Somatostatin; Sympathetic Nervous System; Tetradecanoylphorbol Acetate

1993
Differential protein kinase C ligand regulation detected in vivo by a phenotypic yeast assay.
    Molecular carcinogenesis, 1995, Volume: 12, Issue:3

    Topics: Animals; Base Sequence; Carcinogens; Catalysis; Cattle; Cell Division; Cloning, Molecular; Diterpenes; Drug Evaluation, Preclinical; Indoles; Lactams; Ligands; Molecular Sequence Data; Mutation; Phenotype; Protein Kinase C; Regulatory Sequences, Nucleic Acid; Saccharomyces cerevisiae; Terpenes; Tetradecanoylphorbol Acetate

1995
Cellular mechanisms mediating the stimulation of ovine endometrial secretion of prostaglandin F2 alpha in response to oxytocin: role of phospholipase C and diacylglycerol.
    The Journal of endocrinology, 1994, Volume: 141, Issue:3

    Topics: Animals; Arginine Vasopressin; Diglycerides; Dinoprost; Endometrium; Enzyme Activation; Estrenes; Female; In Vitro Techniques; Indoles; Lactams; Lithium Chloride; Ovariectomy; Oxytocin; Pyrimidinones; Pyrrolidinones; Sheep; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiazoles; Time Factors; Type C Phospholipases

1994
Activation of conventional mammalian protein kinase C isoforms expressed in budding yeast modulates the cell doubling time--a potential in vivo screen for protein kinase C activators.
    Cancer detection and prevention, 1996, Volume: 20, Issue:6

    Topics: Animals; Bryostatins; Cattle; Cell Division; Diterpenes; Enzyme Activation; Indoles; Isoenzymes; Lactams; Lactones; Macrolides; Phorbol Esters; Plasmids; Protein Kinase C; Saccharomyces cerevisiae; Sequence Deletion; Terpenes; Tetradecanoylphorbol Acetate

1996
Induction of cell cornification and enhanced squamous-cell marker SPRR1 gene expression by phorbol ester are regulated by different signaling pathways in human conducting airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:5

    Topics: Biomarkers; Cell Size; Cornified Envelope Proline-Rich Proteins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Indoles; Lactams; Maleimides; Membrane Proteins; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinases; Protein Kinase C; Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Transcriptional Activation

2000
Defective lipopolysaccharide-dependent ERK 1/2 activation in endotoxin tolerant murine macrophages is reversed by direct protein kinase C stimulation.
    Shock (Augusta, Ga.), 2000, Volume: 14, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Drug Tolerance; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Indoles; Lactams; Lipopolysaccharides; Macrophages, Peritoneal; Male; Maleimides; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2000
Enhancing effect of tumor promoters, phorbol esters and teleocidins on nuclear receptor-mediated transcription.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: Animals; Carcinogens; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Lactams; Luciferases; Lyngbya Toxins; Nuclear Receptor Subfamily 1, Group F, Member 1; Okadaic Acid; Plasmids; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Tetradecanoylphorbol Acetate; Thapsigargin; Thymidine Kinase; Trans-Activators; Transcription, Genetic; Transfection

2000
Enhancement of cisplatin sensitivity of cisplatin-resistant human cervical carcinoma cells by bryostatin 1.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Caspase 3; Caspases; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Female; HeLa Cells; Humans; Indoles; Lactams; Macrolides; Phorbol 12,13-Dibutyrate; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA Interference; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection; Uterine Cervical Neoplasms

2005
Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts.
    Molecular pharmacology, 2014, Volume: 86, Issue:4

    Topics: Actinobacteria; Animals; Biological Products; HEK293 Cells; High-Throughput Screening Assays; Humans; Indoles; Lactams; Maleimides; Myocytes, Smooth Muscle; Phenotype; Protein Kinase C beta; Protein Kinase Inhibitors; Rats; Receptor, Muscarinic M3; RGS Proteins; Small Molecule Libraries; Tetradecanoylphorbol Acetate; Up-Regulation

2014