tetradecanoylphorbol acetate has been researched along with guanosine triphosphate in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (37.14) | 18.7374 |
| 1990's | 73 (52.14) | 18.2507 |
| 2000's | 15 (10.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clementi, E; Meldolesi, J; Raichman, M; Scheer, H | 1 |
| Mitchison, TJ; Symons, MH | 1 |
| Kaziro, Y; Nakafuku, M; Satoh, T | 1 |
| Chau, LY | 1 |
| Jackson, RC; Koopmann, WR | 1 |
| De Lisle, RC; Kitagawa, M; Williams, JA | 1 |
| Boal, TR; Cohen, RB; Safer, B | 1 |
| Cantraine, F; Christophe, J; Dehaye, JP; Delporte, C; Poloczek, P; Winand, J | 1 |
| Kaziro, Y; Miyajima, A; Nakafuku, M; Satoh, T | 1 |
| Andersson, LC; Mustelin, T; Nordström, T; Pessa-Morikawa, T | 1 |
| Koza, RA; Megosh, LC; O'Brien, TG; Palmieri, M | 1 |
| Bos, JL; Burgering, BM; Medema, RH | 1 |
| Abramson, JS; Ralston, EP; Wagner, MP; Wei, Y; Wheeler, JG | 1 |
| Olianas, MC; Onali, P | 2 |
| Gardner, SD; Palmer, S; Plevin, R; Wakelam, MJ | 1 |
| Akiba, S; Fujii, T; Sato, T | 3 |
| Drenth, JP; Khalil, RA; Nishimura, J; van Breemen, C | 1 |
| Carroll, AG; Rhoads, AR; Wagner, PD | 1 |
| Dufau, ML; Fabbri, A; Tinajero, JC; Ulisse, S | 1 |
| Teitelbaum, I | 1 |
| Kajiyama, Y; Murayama, T; Nomura, Y | 1 |
| Cioffi, CL; Fisher, SK | 1 |
| Hartfield, PJ; Robinson, JM | 1 |
| Clark, RB; Dixon, RA; Friedman, J; Johnson, JA; Strader, CD | 1 |
| Fauci, AS; Folks, TM; Kinter, AL; Maury, W; Poli, G | 1 |
| Alexander, DR; Cantrell, DA; Crumpton, MJ; Graves, JD; Lucas, SC | 1 |
| Abou-Samra, AB; Aguilera, G; Catt, KJ; Harwood, JP; Manganiello, VC | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Jungblut, P; Schultz, G; Seifert, R | 1 |
| Huang, CL; Ives, HE | 1 |
| Kakkar, VV; Krishnamurthi, S; Wheeler-Jones, CP | 1 |
| Igusa, Y; Miyazaki, S; Swann, K | 1 |
| Baumann, I; Dobbelaere, DA; Herrlich, P; Ivanov, V; Stein, B; Williams, RO | 1 |
| Gomperts, BD; Howell, TW; Kramer, IM | 1 |
| Burgoyne, RD; Morgan, A; O'Sullivan, AJ | 1 |
| Baldassare, JJ; Fisher, GJ; Henderson, PA | 1 |
| Cockcroft, S; Geny, B; Stutchfield, J | 1 |
| Björo, T; Gautvik, KM; Gordeladze, JO; Haug, E; Ostberg, BC; Torjesen, PA | 1 |
| Jaggi, C; Li, G; Regazzi, R; Ullrich, S; Wollheim, CB | 1 |
| Aunis, D; Bader, MF; Sontag, JM; Thiersé, D | 1 |
| Bennett, TE; Driver, AG; Kukoly, CA | 1 |
| Bauer, C; Pfeilschifter, J | 1 |
| Cockcroft, S; Stutchfield, J | 1 |
| Kondo, Y; Okajima, F; Sho, K | 1 |
| Hughes, J; Lo, WW | 1 |
| Ishibashi, S; Kurokawa, T; Une, Y; Yamashita, A | 1 |
| Harnett, MM; Klaus, GG | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M | 1 |
| Bell, JD; Brunton, LL; Buxton, IL | 1 |
| Bell, JD; Brunton, LL | 2 |
| Imaizumi, T; Mizushima, A; Osugi, T; Uchida, S; Yoshida, H | 1 |
| Devanney, JF; Huang, CK; Kanaho, Y | 1 |
| Biden, TJ; Vallar, L; Wollheim, CB | 1 |
| Becker, EL; Kanaho, Y; Matsumoto, T; Molski, TF; Sha'afi, RI | 1 |
| Smith, CD; Snyderman, R; Uhing, RJ | 1 |
| Mueller, GC; Tettenborn, CS | 1 |
| Kakkar, VV; Krishnamurthi, S | 1 |
| Penner, R | 1 |
| Bauer, S; Jakobs, KH | 1 |
| Endo, Y; Kopf, GS; Lee, MA | 1 |
| Gavaret, JM; Jacquemin, C; Matricon, C; Pierre, M; Pomerance, M; Toru-Delbauffe, D | 1 |
| Ahnert-Hilger, G; Bräutigam, M; Gratzl, M | 1 |
| Llano, I; Marty, A | 1 |
| Ikeda, K; Kikuchi, A; Kozawa, O; Takai, Y | 1 |
| Jamieson, GA; Muldoon, LL; Villereal, ML | 1 |
| Brown, JH; Orellana, S; Solski, PA | 1 |
| Ballester, R; Furth, ME; Rosen, OM | 1 |
| Knight, DE; Scrutton, MC | 1 |
| Andersson, T; Krause, KH; Lew, PD; Schlegel, W; Waldvogel, FA; Wollheim, CB | 1 |
| Baker, PF; Knight, DE | 1 |
| Bauer, S; Jakobs, KH; Watanabe, Y | 1 |
| Bauer, S; Horn, F; Jakobs, KH; Watanabe, Y | 1 |
| Johnson, GL; Kelleher, DJ; Pessin, JE; Ruoho, AE | 1 |
| Belman, S; Garte, SJ | 1 |
| Hattori, S; Katagiri, K; Katagiri, T; Nakamura, S; Yamamoto, T; Yoshida, T | 1 |
| Guild, SB; McFerran, BW | 1 |
| Bokoch, GM; Chernoff, J; Dong, HJ; Knaus, UG; Morris, S | 1 |
| Baker, KM; Dostal, DE; Du, J; Motel, TJ; Thekkumkara, TJ; Thomas, WG | 1 |
| Bos, JL; Hordijk, PL; Medema, RH; Moolenaar, WH; van Corven, EJ | 1 |
| De Matteis, MA; Di Tullio, G; Kahn, RA; Luini, A; Santini, G | 1 |
| Sharp, GW; Tang, SH; Yaney, GC | 1 |
| Freestone, P; Grant, S; Norris, V; Toth, I | 1 |
| Ekokoski, E; Törnquist, K | 1 |
| Gschwendt, M; Kielbassa, K; Kittstein, W; Marks, F | 1 |
| Briscoe, CP; Cross, M; Martin, A; Wakelam, MJ | 1 |
| Eckhart, W; Schönthal, A; Srinivas, S | 1 |
| Chubb, S; Ford, R; Hittelman, WN; Meyn, RE; Plunkett, W; Robertson, LE; Story, M | 1 |
| Abo, A; Grogan, A; Segal, AW; Webb, MR | 1 |
| Jaconi, ME; Krause, KH; Lew, DP; Monod, A | 1 |
| Hawkins, PT; Jackson, TR; Stephens, L | 1 |
| Kakinuma, K; Kuratsuji, T; Mizunari, H; Namiki, H; Suzuki, K; Tsunawaki, S | 1 |
| Kaczorowski, GJ; Katz, GM; Reuben, JP; Sanchez-Fernandez, M; Suarez-Kurtz, G | 1 |
| Kuratsuji, T; Mizunari, H; Namiki, H; Tsunawaki, S | 1 |
| Kwan-Yeung, L; Wong, K | 1 |
| Escobedo, JA; Fantl, WJ; Kaziro, Y; Satoh, T; Williams, LT | 1 |
| Fu, WM; Lin-Shiau, SY; Yang, SH | 1 |
| Anderson, S; Delovitch, TL; Denhardt, DT; Haliotis, T; Krook, A; Pross, H; Rapoport, MJ; Zhou, YC | 1 |
| Consiglio, E; Di Jeso, B; Formisano, S; Laviola, L; Liguoro, D | 1 |
| Bienek, C; Jakobs, KH; Keller, J; Rümenapp, U; Schmidt, M; von Eichel-Streiber, C | 1 |
| Bondurant, MC; Bu, X; Hagedorn, CH | 1 |
| Hiwasa, T; Sakiyama, S; Sawada, T | 1 |
| Fields, PE; Fitch, FW; Gajewski, TF | 1 |
| Gautero, H; Geny, B; Lecomte, MC; Lukowski, S; Marin, P; Mira, JP; Russo-Marie, F | 1 |
| Buckley, AR; Buckley, DJ; Rao, YP | 1 |
| Jensen, PE | 1 |
| Chen, CY; Faller, DV; Forman, LW | 1 |
| Akao, M; Bremerich, DH; Hirasaki, A; Jones, KA; Warner, DO; Wong, GY | 1 |
| Benito, M; Lorenzo, M; Teruel, T; Valverde, AM | 1 |
| Dabrowski, A; Groblewski, GE; Guan, KL; Schäfer, C; Williams, JA | 1 |
| Avruch, J; Li, X; Vavvas, D; Zhang, XF | 1 |
| Komatsu, M; Noda, M; Sharp, GW | 1 |
| Light, Y; Marais, R; Marshall, CJ; Mason, C; Olson, MF; Paterson, H | 1 |
| Huberman, E; Inai, K; Nakamura, T; Tsutani, H; Ueda, T; Yamauchi, T | 1 |
| Dunne, MJ; James, RF; Sharp, GW; Straub, SG | 1 |
| Feller, SM; Posern, G; Rapp, UR; Weber, CK | 1 |
| Emala, CW; Hirshman, CA; Kuhl, JS; Levitsky, HI; Lindeman, KS | 1 |
| Barnard, D; Clawson, D; Diaz, B; Marshall, M | 1 |
| Fujita, T; Mine, T; Ohnishi, H; Shibata, H; Tsuchida, T; Ueda, N | 1 |
| Akasaki, T; Koga, H; Sumimoto, H | 1 |
| Chiloeches, A; Clerk, A; Marais, R; Marshall, CJ; Paterson, HF; Sugden, PH | 1 |
| Montessuit, C; Thorburn, A | 1 |
| Guan, KL; Stewart, S | 1 |
| Dremier, S; Dumont, JE; Roger, PP; Van Keymeulen, A | 1 |
| Cunningham, ML; Harden, TK; Hepler, JR; Hollinger, S; Waldo, GL | 1 |
| Baldacci, G; Pizon, V | 1 |
| Seiz, JL; Slater, SJ; Stagliano, BA; Stubbs, CD | 1 |
| Blind, M; Böhm, T; Famulok, M; Jackson, CL; Knorr, T; Kolanus, W; Mayer, G; Nagel, W | 1 |
| Cathcart, MK; Hamilton, M; Liao, J; Wolfman, A | 1 |
| de Diego, I; Enrich, C; Grewal, T; Kirchhoff, M; Peiró, S; Pons, M; Tebar, F | 1 |
| Chen, CC; Felczak, A; Mattingly, RR; McCabe, MJ; Rosenspire, AJ | 1 |
| Dominguez, P; Kalyanaraman, VS; Modesto, RR; Pahwa, S; Tamma, SM | 1 |
| Blumberg, PM; Lorenzo, PS; Rambaratsingh, RA; Stone, JC | 1 |
| Endo, T; Sun, P | 1 |
| Caron, E; Lim, J; Patel, JC; Tsun, A; van Kooyk, Y; Wiedemann, A | 1 |
| Acosta, E; Castro, E; Cruzblanca, H; Mendoza, V | 1 |
| Kloog, Y; Levy, R; Makovski, V; Raz, A; Shalom-Feuerstein, R | 1 |
140 other study(ies) available for tetradecanoylphorbol acetate and guanosine triphosphate
| Article | Year |
|---|---|
ATP-induced Ca2+ influx is regulated via a pertussis toxin-sensitive mechanism in a PC12 cell clone.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Clone Cells; GTP-Binding Proteins; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Ion Channels; PC12 Cells; Pertussis Toxin; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
A GTPase controls cell-substrate adhesion in Xenopus XTC fibroblasts.
Topics: Amino Acid Sequence; Animals; Cell Adhesion; Cell Line; Cytoskeleton; Dimethyl Sulfoxide; Fibroblasts; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Sequence Data; Oligopeptides; Pseudopodia; Tetradecanoylphorbol Acetate; Xenopus | 1992 |
Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells.
Topics: Animals; Cell Differentiation; Fibroblast Growth Factors; Genistein; Guanosine Triphosphate; In Vitro Techniques; Interleukin-6; Isoflavones; Nerve Growth Factors; PC12 Cells; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Vanadates | 1992 |
Protein kinase C is not involved in the desensitization of platelet activating factor receptor in rabbit platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Platelets; Cell Membrane; Guanosine Triphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Neomycin; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1991 |
Calcium- and guanine-nucleotide-dependent exocytosis in permeabilized rat mast cells. Modulation by protein kinase C.
Topics: Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Digitonin; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine Release; Kinetics; L-Lactate Dehydrogenase; Male; Mast Cells; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Amylase release from streptolysin O-permeabilized pancreatic acini.
Topics: Alkaloids; Amylases; Animals; Bacterial Proteins; Calcium; Cell Membrane Permeability; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Male; Mice; Pancreas; Protein Kinase C; Staurosporine; Streptolysins; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Increased eIF-2 alpha expression in mitogen-activated primary T lymphocytes.
Topics: Cell Nucleus; Cells, Cultured; Eukaryotic Initiation Factor-2; Guanosine Triphosphate; Humans; Kinetics; Lymphocyte Activation; Phytohemagglutinins; RNA; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
The metabolic effects of guanyl nucleotides on rat pancreatic acini permeabilized with streptolysin O suggest a widespread use of G proteins.
Topics: Amylases; Animals; Arachidonic Acid; Bacterial Proteins; Calcium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Inositol Phosphates; Male; Pancreas; Permeability; Rats; Rats, Inbred Strains; Streptolysins; Tetradecanoylphorbol Acetate | 1991 |
Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.
Topics: Animals; Calcium; Cell Line; Epidermal Growth Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Interleukins; Ionomycin; Lymphocytes; Mice; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-2; Receptors, Interleukin-3; Receptors, Interleukin-4; Receptors, Mitogen; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
GTP-binding membrane proteins in activated and differentiating T cells.
Topics: Cell Differentiation; Cell Line; Cells, Cultured; Flow Cytometry; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Lymphocyte Activation; Membrane Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Guanosine Triphosphate; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Insulin-induced p21ras activation does not require protein kinase C, but a protein sensitive to phenylarsine oxide.
Topics: 3T3 Cells; Animals; Arsenicals; Down-Regulation; Gene Expression; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Insulin; Mice; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Receptor, Insulin; Receptors, Antigen, T-Cell; Signal Transduction; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate | 1991 |
The ability of polymorphonuclear leukocyte priming agents to overcome influenza A virus-induced cell dysfunction.
Topics: Diglycerides; Granulocyte-Macrophage Colony-Stimulating Factor; Guanosine Triphosphate; Hemagglutinin Glycoproteins, Influenza Virus; Hemagglutinins, Viral; Humans; In Vitro Techniques; Influenza A virus; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Recombinant Proteins; Tetradecanoylphorbol Acetate; Viral Envelope Proteins | 1991 |
Alteration of the GTP-dependent inhibitory pathway of rat striatal adenylate cyclase by phorbol esters.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Corpus Striatum; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Male; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Regulation of bombesin-stimulated inositol 1,4,5-trisphosphate generation in Swiss 3T3 fibroblasts by a guanine-nucleotide-binding protein.
Topics: Animals; Bombesin; Cell Membrane Permeability; Cells, Cultured; Drug Synergism; Fibroblasts; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Mice; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets.
Topics: Alkaloids; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane Permeability; Chlorides; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Protein Kinase C; Rabbits; Saponins; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Evidence for increased myofilament Ca2+ sensitivity in norepinephrine-activated vascular smooth muscle.
Topics: Actin Cytoskeleton; Animals; Calcium; Cytoskeleton; Egtazic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Rats; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1990 |
Hydrolysis-resistant GTP analogs stimulate catecholamine release from digitonin-permeabilized PC12 cells.
Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cell Membrane Permeability; Digitonin; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hydrolysis; Kinetics; Norepinephrine; Pheochromocytoma; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1990 |
A novel mechanism of action of corticotropin releasing factor in rat Leydig cells.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Cells, Cultured; Chorionic Gonadotropin; Corticotropin-Releasing Hormone; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Leydig Cells; Male; Protein Kinase C; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, Neurotransmitter; Sphingosine; Staurosporine; Testosterone; Tetradecanoylphorbol Acetate | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Histamine-stimulated and GTP-binding proteins-mediated phospholipase A2 activation in rabbit platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; Humans; Immune Sera; Kinetics; Norepinephrine; Pertussis Toxin; Phospholipases; Phospholipases A; Phospholipases A2; Rabbits; Receptors, Histamine H1; Serotonin; Tetradecanoylphorbol Acetate; Thionucleotides; Thrombin; Virulence Factors, Bordetella | 1990 |
Reduction of muscarinic receptor density and of guanine nucleotide-stimulated phosphoinositide hydrolysis in human SH-SY5Y neuroblastoma cells following long-term treatment with 12-O-tetradecanoylphorbol 13-acetate or mezerein.
Topics: Calcium; Culture Media; Cytoplasm; Diterpenes; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Inositol Phosphates; Neuroblastoma; Osmolar Concentration; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Tumor Cells, Cultured | 1990 |
Mg.ATP primes superoxide-generating responses in electropermeabilized neutrophils.
Topics: Adenosine Triphosphate; Animals; Cell Membrane Permeability; Electricity; Enzyme Induction; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1990 |
Identification of a specific domain in the beta-adrenergic receptor required for phorbol ester-induced inhibition of catecholamine-stimulated adenylyl cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; Epinephrine; GTP-Binding Proteins; Guanosine Triphosphate; L Cells; Magnesium; Mice; Pertussis Toxin; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells.
Topics: Biological Factors; Bryostatins; Cell Line; Cell Nucleus; Cytokines; Diglycerides; Enzyme Activation; Guanosine Triphosphate; HIV; Humans; Lactones; Leukemia, Promyelocytic, Acute; Macrolides; Mitogens; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Viral Proteins; Virus Replication | 1990 |
A method for measuring protein kinase C activity in permeabilized T lymphocytes by using peptide substrates. Evidence for multiple pathways of kinase activation.
Topics: Antibodies, Monoclonal; Antigens, CD; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Activation; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Signal Transduction; Substrate Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Phorbol 12-myristate 13-acetate and vasopressin potentiate the effect of corticotropin-releasing factor on cyclic AMP production in rat anterior pituitary cells. Mechanisms of action.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Kinetics; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Guanosine 5'-O-(3-thiotrisphosphate) potentiates both thrombin- and platelet-derived growth factor-induced inositol phosphate release in permeabilized vascular smooth muscle cells. Signaling mechanisms distinguished by sensitivity to pertussis toxin and p
Topics: Animals; Cell Membrane Permeability; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Muscle, Smooth, Vascular; Pertussis Toxin; Platelet-Derived Growth Factor; Rats; Signal Transduction; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides; Thrombin; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Differential effects of phorbol 12-myristate 13-acetate on GTP gamma S-induced diacylglycerol formation and arachidonic acid liberation in saponin-permeabilized rabbit platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Lipids; Permeability; Phospholipases A; Phospholipases A2; Rabbits; Saponins; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1989 |
Enhancement of arachidonic acid liberation by protein kinase C activator is partially dependent on extracellular Na+ in rabbit platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Diglycerides; Drug Synergism; Enzyme Activation; Guanosine Triphosphate; Hydrogen-Ion Concentration; Intracellular Membranes; Protein Kinase C; Rabbits; Sodium; Tetradecanoylphorbol Acetate | 1989 |
Effect of phorbol ester treatment on receptor-mediated versus G-protein-activator-mediated responses in platelets. Evidence for a two-site action of phorbol ester at the level of G-protein function.
Topics: Alkaloids; Blood Platelets; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; Male; Phosphatidic Acids; Protein Kinase C; Serotonin; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Time Factors; Type C Phospholipases | 1989 |
Evidence for an inhibitory effect of protein kinase C on G-protein-mediated repetitive calcium transients in hamster eggs.
Topics: Animals; Calcium; Cricetinae; Diglycerides; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mesocricetus; Ovum; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Infection with the intracellular protozoan parasite Theileria parva induces constitutively high levels of NF-kappa B in bovine T lymphocytes.
Topics: Animals; Apicomplexa; Cattle; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Enhancer Elements, Genetic; Guanosine Triphosphate; HIV-1; NF-kappa B; Plasmids; T-Lymphocytes; Tetradecanoylphorbol Acetate; Theileriasis; Transcription Factors; Transcription, Genetic; Transfection | 1989 |
Protein phosphorylation and the dependence on Ca2+ and GTP-gamma-S for exocytosis from permeabilised mast cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane Permeability; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Mast Cells; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
The control of cytoskeletal actin and exocytosis in intact and permeabilized adrenal chromaffin cells: role of calcium and protein kinase C.
Topics: Actins; Adrenal Medulla; Animals; Barium; Calcium; Cattle; Cell Membrane Permeability; Cytoskeleton; Digitonin; Exocytosis; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Neomycin; Nicotine; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Plasma membrane associated phospholipase C from human platelets: synergistic stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by thrombin and guanosine 5'-O-(3-thiotriphosphate).
Topics: Blood Platelets; Cell Membrane; Drug Synergism; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; In Vitro Techniques; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Thrombin; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.
Topics: Calcium; Cell Membrane; Cell Membrane Permeability; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkylation; Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Pertussis Toxin; Pituitary Neoplasms; Polymyxin B; Prolactin; Protein Kinase C; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Different requirements for protein kinase C activation and Ca2+-independent insulin secretion in response to guanine nucleotides. Endogenously generated diacylglycerol requires elevated Ca2+ for kinase C insertion into membranes.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Diglycerides; Enzyme Activation; Glycerides; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Insulin; Insulin Secretion; Kinetics; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
A reassessment of guanine nucleotide effects on catecholamine secretion from permeabilized adrenal chromaffin cells.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Bacterial Toxins; Calcium; Cattle; Cell Membrane Permeability; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysin Proteins; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Neurotoxins; Norepinephrine; Sphingosine; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Expression of histamine H1 receptors on cultured histiocytic lymphoma cells.
Topics: Cycloheximide; Dactinomycin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; Humans; Lymphoma, Large B-Cell, Diffuse; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Different effects of phorbol ester on angiotensin II- and stable GTP analogue-induced activation of polyphosphoinositide phosphodiesterase in membranes isolated from rat renal mesangial cells.
Topics: Angiotensin II; Animals; Cell Membrane; Cells, Cultured; Enzyme Activation; Glomerular Mesangium; Guanosine Triphosphate; Inositol Phosphates; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Rats; Tetradecanoylphorbol Acetate | 1987 |
Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.
Topics: Adenosine Triphosphate; Bacterial Proteins; Calcium; Cell Line; Cell Membrane Permeability; Enzyme Activation; Exocytosis; Glucuronidase; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol Phosphates; L-Lactate Dehydrogenase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Streptolysins; Tetradecanoylphorbol Acetate; Thionucleotides | 1988 |
Inhibition by islet-activating protein, pertussis toxin, of P2-purinergic receptor-mediated iodide efflux and phosphoinositide turnover in FRTL-5 cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cell Line; Cytosol; Guanosine Triphosphate; Inositol Phosphates; Iodides; Iodine Radioisotopes; Molecular Weight; Pertussis Toxin; Phosphatidylinositols; Rats; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Virulence Factors, Bordetella | 1988 |
Differential regulation of cholecystokinin- and muscarinic-receptor-mediated phosphoinositide turnover in Flow 9000 cells.
Topics: Acetylcholine; Cell Line; Guanosine Triphosphate; Humans; Inositol Phosphates; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Cholecystokinin; Receptors, Muscarinic; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester regulates stimulatory and inhibitory pathways of the hormone-sensitive adenylate cyclase system in rat reticulocytes.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Pertussis Toxin; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Reticulocytes; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Protein kinase C activators inhibit the antigen receptor-coupled polyphosphoinositide phosphodiesterase in murine B lymphocytes.
Topics: Animals; B-Lymphocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol Phosphates; Kinetics; Mice; Mice, Inbred CBA; Phorbol Esters; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Protein Kinase C; Receptors, Antigen, B-Cell; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides | 1988 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Cyclic AMP; Drug Synergism; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Manganese; Phorbols; Protein Kinase C; Protein Kinases; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Chlorides; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mathematics; Pertussis Toxin; Phorbol Esters; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Phorbol ester inhibits bradykinin-stimulated inositol trisphosphate formation and calcium mobilization in neuroblastoma x glioma hybrid NG108-15 cells.
Topics: Bradykinin; Calcium; Cell Line; Diglycerides; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Protein Kinase C; Receptors, Bradykinin; Receptors, Neurotransmitter; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1987 |
Regulation of membrane associated protein kinase C activity by guanine nucleotide in rabbit peritoneal neutrophils.
Topics: Animals; Calcium; Cell Membrane; Enzyme Activation; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histones; Membrane Proteins; Neutrophils; Peritoneal Cavity; Phosphatidylinositols; Phosphoproteins; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Thionucleotides | 1987 |
Guanine nucleotides induce Ca2+-independent insulin secretion from permeabilized RINm5F cells.
Topics: Animals; Calcium; Cell Line; Cell Membrane Permeability; Cholera Toxin; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Insulin; Insulin Secretion; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1987 |
G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cell-Free System; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters.
Topics: Calcium; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases; Virulence Factors, Bordetella | 1987 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
12-O-tetradecanoylphorbol-13-acetate activates phosphatidylethanol and phosphatidylglycerol synthesis by phospholipase D in cell lysates.
Topics: Cell Fractionation; Cell Line; Enzyme Activation; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Phosphatidic Acids; Phosphatidylglycerols; Phospholipase D; Phospholipases; Tetradecanoylphorbol Acetate; Thionucleotides; Ultracentrifugation | 1988 |
Phorbol ester treatment inhibits thrombin but not stable GTP analogue-induced platelet granule secretion despite inhibition of phosphatidate formation with both agonists.
Topics: Blood Platelets; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Male; Phosphatidic Acids; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thionucleotides; Thrombin; Time Factors | 1988 |
Multiple signaling pathways control stimulus-secretion coupling in rat peritoneal mast cells.
Topics: Animals; Benzofurans; Calcium; Fura-2; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Mast Cells; Models, Biological; Neomycin; p-Methoxy-N-methylphenethylamine; Peritoneum; Pertussis Toxin; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Phorbol ester treatment impairs hormone- but not stable GTP analog-induced inhibition of adenylate cyclase.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclase Inhibitors; Blood Platelets; Epinephrine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; Lymphoma; Phorbols; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides | 1986 |
Characterization of an islet-activating protein-sensitive site in mouse sperm that is involved in the zona pellucida-induced acrosome reaction.
Topics: Acrosome; Aminoacridines; Animals; Calcimycin; Calcium; Chlortetracycline; Female; Fluorescent Dyes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Mice; Microscopy, Electron; Ovum; Pertussis Toxin; Quinuclidinyl Benzilate; Sperm Capacitation; Spermatozoa; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella; Zona Pellucida | 1988 |
Properties of the 12-O-tetradecanoylphorbol-13-acetate-stimulated S6 kinase from rat astroglial cells.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Cations; Centrifugation, Density Gradient; Chromatography; Dithiothreitol; Ethylmaleimide; Guanosine Triphosphate; Magnesium; Phosphorylation; Protein Kinases; Rats; Rats, Inbred Strains; Ribosomal Protein S6 Kinases; Substrate Specificity; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 1988 |
Ca2+-stimulated catecholamine release from alpha-toxin-permeabilized PC12 cells: biochemical evidence for exocytosis and its modulation by protein kinase C and G proteins.
Topics: Adrenal Gland Neoplasms; Animals; Bacterial Toxins; Calcium; Cell Line; Cell Membrane Permeability; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hemolysin Proteins; Kinetics; Neurotoxins; Nigericin; Norepinephrine; Pheochromocytoma; Tetradecanoylphorbol Acetate; Thionucleotides | 1987 |
Protein kinase C activators inhibit the inositol trisphosphate-mediated muscarinic current responses in rat lacrimal cells.
Topics: Acetylcholine; Animals; Calcium; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lacrimal Apparatus; Protein Kinase C; Rats; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides | 1987 |
Modes of inhibitory action of protein kinase C in the chemotactic peptide-induced formation of inositol phosphates in differentiated human leukemic (HL-60) cells.
Topics: 2,3-Diphosphoglycerate; Calcium; Cell Differentiation; Cell Line; Cell Membrane; Diphosphoglyceric Acids; Guanosine Triphosphate; Humans; Inositol Phosphates; Kinetics; Leukemia, Myeloid, Acute; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1987 |
Calcium mobilization in permeabilized fibroblasts: effects of inositol trisphosphate, orthovanadate, mitogens, phorbol ester, and guanosine triphosphate.
Topics: Biological Transport, Active; Calcium; Cell Membrane Permeability; Cells, Cultured; Digitonin; Fibroblasts; Growth Substances; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Mitogens; Skin; Sugar Phosphates; Tetradecanoylphorbol Acetate; Vanadates; Vanadium | 1987 |
Guanosine 5'-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membranes is inhibited by phorbol ester and protein kinase C.
Topics: Bradykinin; Carbachol; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membranes; Phorbol Esters; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Muscarinic; Sugar Phosphates; Tetradecanoylphorbol Acetate; Thionucleotides | 1987 |
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product.
Topics: Adrenal Cortex; Amino Acid Sequence; Animals; Cell Line; Diglycerides; GTP Phosphohydrolases; Guanosine Triphosphate; Phosphatidylserines; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate | 1987 |
Phorbol esters increase GTP-dependent adenylate cyclase activity in rat brain striatal membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Corpus Striatum; Dopamine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Effect of various excitatory agonists on the secretion of 5-hydroxytryptamine from permeabilised human platelets induced by Ca2+ in the presence or absence of GTP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Calcium; Cell Membrane Permeability; Diglycerides; Dose-Response Relationship, Drug; Epinephrine; Guanosine Triphosphate; Humans; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation.
Topics: Calcium; Cell Line; Cytoplasmic Granules; Ethers; Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Ionomycin; Leukemia, Myeloid, Acute; Lymphocyte Activation; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Guanine nucleotides and Ca-dependent exocytosis. Studies on two adrenal cell preparations.
Topics: Adrenal Glands; Animals; Calcium; Cattle; Chickens; Diglycerides; Exocytosis; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Tetradecanoylphorbol Acetate; Thionucleotides | 1985 |
Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Catalysis; Colforsin; Diterpenes; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Humans; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Protein kinase C interferes with Ni-mediated inhibition of human platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Blood Platelets; Cell Membrane; Chickens; Colforsin; Enzyme Activation; Epinephrine; Female; Guanosine Triphosphate; Humans; Oviducts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Isoproterenol; Phorbols; Phosphorylation; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors; Turkeys | 1984 |
Tumour promoter uncouples beta-adrenergic receptor from adenyl cyclase in mouse epidermis.
Topics: Adenylyl Cyclases; Animals; Cell-Free System; Cyclic AMP; Enzyme Activation; Epidermis; Female; Guanosine Triphosphate; Isoproterenol; Membrane Fluidity; Mice; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1980 |
Activation of Ras and formation of GAP complex during TPA-induced monocytic differentiation of HL-60 cells.
Topics: Benzoquinones; Cell Differentiation; Dexamethasone; Enzyme Activation; Granulocytes; GTPase-Activating Proteins; Guanosine Triphosphate; Humans; Lactams, Macrocyclic; Monocytes; Mutation; Oncogene Protein p21(ras); Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Quinones; ras GTPase-Activating Proteins; Rifabutin; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured; Tyrosine | 1994 |
The effects of calyculin A upon calcium-, guanine nucleotides- and phorbol 12-myristate 13-acetate-stimulated ACTH secretion from AtT-20 cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Guanine Nucleotides; Guanosine Triphosphate; Marine Toxins; Mice; Oxazoles; Phosphoprotein Phosphatases; Pituitary Neoplasms; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1995 |
Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors.
Topics: Adenosine Triphosphate; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Neutrophil Activation; Neutrophils; p21-Activated Kinases; Pertussis Toxin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1995 |
Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: rapid desensitization by angiotensin II.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Base Sequence; Calcium; Cell Membrane; CHO Cells; Concanavalin A; Cricetinae; Gene Expression; Guanosine Triphosphate; Imidazoles; Losartan; Membrane Potentials; Molecular Sequence Data; Pyridines; Rats; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Tetrazoles; Transfection; Verapamil | 1995 |
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts.
Topics: Adenylate Cyclase Toxin; Animals; Cell Line; Cholera Toxin; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Lysophospholipids; Pertussis Toxin; Phosphates; Phosphotyrosine; Proto-Oncogene Proteins p21(ras); Receptors, Cell Surface; Receptors, Thrombin; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Thrombin; Tyrosine; Virulence Factors, Bordetella | 1993 |
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex.
Topics: ADP-Ribosylation Factors; Aluminum; Animals; Brefeldin A; Cell Membrane Permeability; Coatomer Protein; Cyclopentanes; Enzyme Activation; Fluorine; Glycosaminoglycans; Golgi Apparatus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Microtubule-Associated Proteins; Naphthalenes; Phorbol Esters; Polycyclic Compounds; Protein Binding; Protein Kinase C; Rats; Receptors, IgE; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Unusual carbachol responses in RINm5F cells: evidence for a "distal" site of action in stimulus-secretion coupling.
Topics: Arachidonic Acid; Calcium; Carbachol; Cells, Cultured; Guanosine Triphosphate; Insulin; Insulin Secretion; Membrane Potentials; Protein Kinase C; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Identification of phosphoproteins in Escherichia coli.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Calcium; Escherichia coli; Escherichia coli Proteins; Guanosine Triphosphate; HSP70 Heat-Shock Proteins; Molecular Sequence Data; Molecular Weight; Nucleoside-Diphosphate Kinase; Phosphoproteins; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Ribosomal Proteins; Signal Transduction; Succinate-CoA Ligases; Tetradecanoylphorbol Acetate | 1995 |
Evidence for a pertussis toxin sensitive calcium entry pathway in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Extracellular Space; Fura-2; Guanosine Triphosphate; Intracellular Membranes; Pertussis Toxin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Gland; Virulence Factors, Bordetella | 1995 |
Protein kinase C delta accepts GTP for autophosphorylation.
Topics: Adenosine Triphosphate; Animals; Bryostatins; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Isoenzymes; Kinetics; Lactones; Macrolides; Mitogens; Peptide Mapping; Phosphopeptides; Phosphorylation; Protein Kinase C; Spleen; Substrate Specificity; Swine; Tetradecanoylphorbol Acetate | 1995 |
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Genistein; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Isoflavones; Kinetics; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Polyomavirus middle-sized tumor antigen modulates c-Jun phosphorylation and transcriptional activity.
Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Chloramphenicol O-Acetyltransferase; Gene Expression; Genes, jun; Genes, ras; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-raf; Proto-Oncogenes; ras Proteins; Serine; Tetradecanoylphorbol Acetate; Threonine; Transcription, Genetic; Transfection | 1994 |
Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine.
Topics: Adenosine Triphosphate; Apoptosis; Cladribine; Cycloheximide; Dactinomycin; DNA, Neoplasm; Egtazic Acid; Guanosine Triphosphate; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Microscopy, Electron; Puromycin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine Triphosphate; Vidarabine | 1993 |
Activation of NADPH oxidase involves the dissociation of p21rac from its inhibitory GDP/GTP exchange protein (rhoGDI) followed by its translocation to the plasma membrane.
Topics: Amino Acid Sequence; Biological Transport; Cell Membrane; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotide Dissociation Inhibitors; Guanosine Triphosphate; Humans; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; rac GTP-Binding Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements.
Topics: Biological Transport; Calcium; Cell Line; Granulocytes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; N-Formylmethionine Leucyl-Phenylalanine; Sodium Fluoride; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides | 1993 |
Activation of phosphatidylinositol 4,5-bisphosphate supply by agonists and non-hydrolysable GTP analogues.
Topics: Cell Membrane Permeability; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Indoles; Inositol; Inositol Phosphates; Kinetics; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphatidylinositol Phosphates; Phosphorus Radioisotopes; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Nucleoside-triphosphate binding of the two cytosolic components of the respiratory burst oxidase system: evidence for its inhibition by the 2',3'-dialdehyde derivative of NADPH and desensitization in their translocated states.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Biological Transport, Active; Cytosol; Guanosine Triphosphate; Humans; Kinetics; Molecular Sequence Data; Myristic Acid; Myristic Acids; NADH, NADPH Oxidoreductases; NADP; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; Precipitin Tests; Species Specificity; Swine; Tetradecanoylphorbol Acetate | 1993 |
Mobilization of intracellular calcium in cultured vascular smooth muscle cells by uridine triphosphate and the calcium ionophore A23187.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Cytidine Triphosphate; GTP-Binding Proteins; Guanosine Triphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Pertussis Toxin; Potassium Channels; Protein Kinase C; Tetradecanoylphorbol Acetate; Uridine Triphosphate; Virulence Factors, Bordetella | 1993 |
Activation of respiratory burst oxidase is accompanied by desensitization of p47phox in nucleoside-triphosphate binding along with its translocation to cell membrane.
Topics: Adenosine Triphosphate; Cell Membrane; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Guanosine Triphosphate; Humans; Kinetics; NADH, NADPH Oxidoreductases; NADP; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; Ribonucleotides; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Sphingosine mobilizes intracellular calcium in human neutrophils.
Topics: Biological Transport; Calcium; Cell Compartmentation; Cell Death; Dose-Response Relationship, Drug; Edetic Acid; Fluorescent Dyes; Fura-2; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylcholine; Saponins; Sphingosine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Line; CHO Cells; Cricetinae; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Interleukin-3; Kinetics; Mice; Phosphatidylinositol 3-Kinases; Phosphotransferases; Platelet-Derived Growth Factor; Proteins; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 1993 |
Potentiation of miniature endplate potential frequency by ATP in Xenopus tadpoles.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Enzyme Activation; Guanosine Triphosphate; Membrane Potentials; Microelectrodes; Motor Endplate; Protein Kinases; Tetradecanoylphorbol Acetate; Xenopus laevis | 1993 |
p21ras and protein kinase C function in distinct and interdependent signaling pathways in C3H 10T1/2 fibroblasts.
Topics: Animals; Cell Adhesion; Cell Line; DNA, Antisense; Down-Regulation; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Mice, Inbred C3H; Models, Genetic; Osteopontin; Protein Kinase C; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Sialoglycoproteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
P2 purinergic agonists and 12-O-tetradecanoylphorbol-13-acetate, as well as protein kinase A activators, stimulate thyroglobulin secretion in FRTL-5 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenosine Triphosphate; Cells, Cultured; Colforsin; Enzyme Activation; Guanosine Triphosphate; Protein Kinases; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroglobulin | 1993 |
Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins.
Topics: ADP Ribose Transferases; Bacterial Proteins; Bacterial Toxins; Botulinum Toxins; Cell Line; Clostridioides difficile; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Muscarinic Antagonists; Phospholipase D; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Erythropoietin stimulates phosphorylation of eIF-4E and identification of a 37-kD phosphoprotein that binds mRNA caps in erythroblasts.
Topics: Anemia; Animals; Erythroblasts; Erythropoietin; Ethers, Cyclic; Eukaryotic Initiation Factor-4E; Female; Friend murine leukemia virus; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Molecular Weight; Okadaic Acid; Peptide Initiation Factors; Phosphoproteins; Phosphorylation; RNA Caps; RNA, Messenger; Spleen; Tetradecanoylphorbol Acetate | 1996 |
Synergistic induction of anchorage-independent growth of NIH3T3 mouse fibroblasts by cysteine proteinase inhibitors and a tumor promoter.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Carcinogens; Cell Adhesion; Cell Division; Cell Line, Transformed; Cystatins; Dexamethasone; Drug Synergism; Gene Expression; Guanosine Triphosphate; Mice; Molecular Sequence Data; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Blocked Ras activation in anergic CD4+ T cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CD4 Antigens; Clonal Anergy; Clone Cells; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); ras Guanine Nucleotide Exchange Factors; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Th1 Cells | 1996 |
Inhibition of phospholipase D activity by fodrin. An active role for the cytoskeleton.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Calpain; Carrier Proteins; Cattle; Cytoskeleton; Enzyme Activation; Guanosine Triphosphate; HL-60 Cells; Humans; Microfilament Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phospholipases A; Signal Transduction; Spectrin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Rapid activation of mitogen-activated protein kinase and p21ras by prolactin and interleukin 2 in rat Nb2 node lymphoma cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Activation; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Interleukin-2; Isoflavones; Lymph Nodes; Lymphoma, T-Cell; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Calphostin C-sensitive enhancements of force by lysophosphatidylinositol and diacylglycerols in mesenteric arteries from the rat.
Topics: Animals; Calcium; Diglycerides; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Lysophospholipids; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Norepinephrine; Permeability; Protein Kinase C; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases | 1996 |
Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-ras.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclosporine; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Gene Expression; Genes, Immediate-Early; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Immediate-Early Proteins; Ionomycin; Lymphocyte Activation; Models, Biological; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Halothane reduces myofilament Ca2+ sensitivity during muscarinic receptor stimulation of airway smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Cell Membrane Permeability; Cytosol; Dogs; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Halothane; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Trachea | 1996 |
Alterations in the insulin signaling pathway induced by immortalization and H-ras transformation of brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Alkaline Phosphatase; Animals; Blotting, Western; Cell Line, Transformed; Dose-Response Relationship, Drug; Fetus; Guanosine Triphosphate; Insulin; Insulin Resistance; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Receptor, Insulin; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Threonine; Transfection | 1997 |
Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell-Free System; Cells, Cultured; Cholecystokinin; Enzyme Activation; Epidermal Growth Factor; Glutathione Transferase; Guanosine Triphosphate; Humans; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Pancreas; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; ras Proteins; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Identification of Nore1 as a potential Ras effector.
Topics: Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; DNA-Binding Proteins; Epidermal Growth Factor; Gene Expression Regulation; GTP-Binding Proteins; Guanosine Triphosphate; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Nuclear Proteins; Protein Binding; ras Proteins; Rats; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate | 1998 |
Nutrient augmentation of Ca2+-dependent and Ca2+-independent pathways in stimulus-coupling to insulin secretion can be distinguished by their guanosine triphosphate requirements: studies on rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mycophenolic Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chlorocebus aethiops; COS Cells; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Guanosine Triphosphate; Indoles; Mutation; Protein Kinase C; Proto-Oncogene Proteins c-raf; ras Proteins; Receptor, Muscarinic M1; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Low GTP induces PKC-beta-dependent myeloid cell differentiation.
Topics: Cell Differentiation; Cell Division; Guanosine Triphosphate; HL-60 Cells; Humans; Isoenzymes; Kinetics; Mycophenolic Acid; Protein Kinase C; Protein Kinase C beta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Humans; Insulin; Insulin Secretion; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Keto Acids; Male; Mannoheptulose; Organ Culture Techniques; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wasp Venoms | 1998 |
Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Becaplermin; Bombesin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Division; Cytochalasin D; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Mice; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins c-sis; rap GTP-Binding Proteins; ras Proteins; Tetradecanoylphorbol Acetate; Transcription Factors | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms.
Topics: Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; Epidermal Growth Factor; Gene Expression Regulation; Guanosine Triphosphate; Molecular Sequence Data; Oncogenes; Phosphorylation; Proto-Oncogene Proteins c-raf; ras Proteins; Sequence Homology, Amino Acid; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Involvement of Rab4 in regulated exocytosis of rat pancreatic acini.
Topics: Amino Acid Sequence; Amylases; Animals; Calcium; Cholecystokinin; Exocytosis; Fluorescent Antibody Technique; Glucose Transporter Type 4; GTP-Binding Proteins; Guanosine Triphosphate; Guinea Pigs; Molecular Sequence Data; Monosaccharide Transport Proteins; Muscle Proteins; Naphthalenes; Pancreas; rab4 GTP-Binding Proteins; Rats; Tetradecanoylphorbol Acetate | 1999 |
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils.
Topics: Androstadienes; Chromones; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Indoles; Leukotriene B4; Maleimides; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin | 1999 |
Regulation of Ras.GTP loading and Ras-Raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester. Activation of the extracellular signal-regulated kinase cascade by phorbol ester is mediated by Ras.
Topics: Animals; Cells, Cultured; Cyclic AMP; Down-Regulation; Endothelin-1; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Pertussis Toxin; Phenylephrine; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Activation of Ras by phorbol esters in cardiac myocytes. Role of guanine nucleotide exchange factors.
Topics: Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Lovastatin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Phenanthridines; Protein Kinase C; ras Proteins; Rats; Tetradecanoylphorbol Acetate | 1999 |
The dominant negative Ras mutant, N17Ras, can inhibit signaling independently of blocking Ras activation.
Topics: Cell Transformation, Neoplastic; DNA-Binding Proteins; ets-Domain Protein Elk-1; Genes, ras; Growth Substances; Guanosine Diphosphate; Guanosine Triphosphate; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Phosphorylation; Proto-Oncogene Proteins; ras Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 2000 |
TSH and cAMP do not signal mitogenesis through Ras activation.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Activation; Epidermal Growth Factor; Guanosine Triphosphate; Hepatocyte Growth Factor; Insulin; Mitogens; ras Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 2000 |
Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling.
Topics: Animals; Enzyme Activation; Erythrocyte Membrane; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; GTPase-Activating Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Inositol Phosphates; Phosphorylation; Protein Kinase C; Receptors, Adrenergic, beta; Receptors, Purinergic; RGS Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Turkeys | 2001 |
Rap1A protein interferes with various MAP kinase activating pathways in skeletal myogenic cells.
Topics: Androstadienes; Blood Proteins; Blotting, Western; Cell Division; Cell Line; Cyclic AMP; Down-Regulation; Enzyme Activation; Flavonoids; Guanosine Diphosphate; Guanosine Triphosphate; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; rap1 GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Wortmannin | 2000 |
Interaction of protein kinase C isozymes with Rho GTPases.
Topics: Animals; Calcium; Cations, Divalent; cdc42 GTP-Binding Protein; Dose-Response Relationship, Drug; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; Isoenzymes; Membrane Lipids; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; rac1 GTP-Binding Protein; Rats; Recombinant Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers.
Topics: Actins; ADP-Ribosylation Factor 1; Amino Acid Sequence; Base Sequence; Cell Adhesion; Cell Adhesion Molecules; Cell Size; Cytoskeleton; Fungal Proteins; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Intercellular Adhesion Molecule-1; Jurkat Cells; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Binding; Protein Structure, Tertiary; RNA; Saccharomyces cerevisiae Proteins; Substrate Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2001 |
Constitutive association of c-N-Ras with c-Raf-1 and protein kinase C epsilon in latent signaling modules.
Topics: Animals; Cell Line; Cell Line, Transformed; Cell Membrane; Culture Media, Serum-Free; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Genes, ras; Guanosine Triphosphate; Isoenzymes; Kinetics; Mice; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Protein Kinase C-epsilon; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Activation of Raf-1 is defective in annexin 6 overexpressing Chinese hamster ovary cells.
Topics: Animals; Annexin A6; CHO Cells; Cricetinae; Enzyme Activation; Epidermal Growth Factor; Guanosine Triphosphate; Mitogen-Activated Protein Kinases; Protein Binding; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Low concentrations of inorganic mercury inhibit Ras activation during T cell receptor-mediated signal transduction.
Topics: Antibodies, Monoclonal; CD3 Complex; Enzyme Activation; Guanosine Triphosphate; Humans; Jurkat Cells; Mercury; Mitogen-Activated Protein Kinases; ras Proteins; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.
Topics: Adult; CD4 Antigens; CD4-Positive T-Lymphocytes; Cell Cycle Proteins; Clonal Anergy; Enzyme Activation; Guanosine Diphosphate; Guanosine Triphosphate; HIV Envelope Protein gp120; HIV-1; Humans; Interleukin-2; Ionomycin; JNK Mitogen-Activated Protein Kinases; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Phospholipase C gamma; Phosphorylation; Plant Lectins; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-vav; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; ZAP-70 Protein-Tyrosine Kinase | 2003 |
RasGRP1 represents a novel non-protein kinase C phorbol ester signaling pathway in mouse epidermal keratinocytes.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Cells; Epidermis; Flow Cytometry; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoblotting; Keratin-10; Keratinocytes; Keratins; Mice; Neoplasms, Experimental; Phorbol Esters; Precipitin Tests; Protein Kinase C; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Assays for functional properties of Rab34 in macropinosome formation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Thin Layer; DNA Primers; Epitopes; GTP Phosphohydrolases; Guanosine Triphosphate; Mice; Platelet-Derived Growth Factor; Point Mutation; rab GTP-Binding Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2005 |
Two distinct cytoplasmic regions of the beta2 integrin chain regulate RhoA function during phagocytosis.
Topics: Actins; Amino Acid Sequence; Animals; CD18 Antigens; Cell Line, Tumor; Chlorocebus aethiops; Complement C3b; COS Cells; Erythrocytes; Guanosine Triphosphate; Macrophage-1 Antigen; Macrophages; Mice; Molecular Sequence Data; Mutation; Phagocytosis; Phagosomes; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2006 |
Modulation of a delayed-rectifier K+ current by angiotensin II in rat sympathetic neurons.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Delayed Rectifier Potassium Channels; Electric Stimulation; Guanosine Diphosphate; Guanosine Triphosphate; Losartan; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoconstrictor Agents | 2007 |
Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras.
Topics: Animals; Blotting, Western; Cricetinae; Epidermal Growth Factor; Galectin 3; Genes, ras; Guanosine Triphosphate; Humans; Immunoprecipitation; Neoplasms; ras Guanine Nucleotide Exchange Factors; ras Proteins; Rats; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2008 |