tetradecanoylphorbol acetate has been researched along with glycerophosphoinositol 4,5-bisphosphate in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (36.92) | 18.7374 |
| 1990's | 30 (46.15) | 18.2507 |
| 2000's | 8 (12.31) | 29.6817 |
| 2010's | 3 (4.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, S; Nigam, S; Walzog, B | 1 |
| Paul, A; Plevin, R; Stewart, A; Wakelam, MJ | 1 |
| Rodríguez Del Castillo, A; Trifaró, JM; Vitale, ML | 1 |
| Doll, S; Hertting, G; Schobert, A; Seregi, A | 1 |
| Tang, W; Ziboh, VA | 1 |
| Callard, RE; Rigley, KP | 1 |
| Clay, K; Dale, MM; Twomey, BM | 1 |
| Koschel, K; Tas, PW | 1 |
| Baldassare, JJ; Fisher, GJ; Henderson, PA; Talwar, HS; Voorhees, JJ | 1 |
| MacNulty, EE; Plevin, R; Wakelam, MJ | 1 |
| Corps, AN; Hesketh, TR; Metcalfe, JC; Moore, JP; Morris, JD; Smith, GA | 1 |
| de Pont, JJ; Haenen, HE; van Nooij, IG; Willems, PH | 1 |
| Lupu-Meiri, M; Oron, Y; Shapira, H | 1 |
| Civitelli, R; Morrissey, J; Ritter, C; Slatopolsky, E; Sugimoto, T | 1 |
| Baldassare, JJ; Fisher, GJ; Henderson, PA | 1 |
| Miller, RJ; Perney, TM | 1 |
| Hohman, R; Kincaid, R; Shevach, EM; Sitkovsky, M; Taffs, R; Trenn, G | 1 |
| Broekman, MJ | 1 |
| Griffor, MC; Scarpa, A; Wiener, EC | 1 |
| Gascard, P; Giraud, F; Sulpice, JC | 1 |
| Downes, CP; Huang, SJ; Monk, PN; Whetton, AD | 1 |
| Broers-Vendrig, CM; de Jong-Brink, M; Dictus, WJ | 1 |
| Berry, AR; Earp, HS; Grisham, JW; Harris, J; Hepler, JR; Lee, LW; McCune, BK; Miller, A; Petch, LA; Raymond, VW | 1 |
| Ibayashi, H; Ikuyama, S; Kato, K; Natori, S; Nawata, H | 1 |
| Barrowman, MM; Cockcroft, S; Gomperts, BD | 1 |
| Feinstein, MB; Halenda, SP; Sha'afi, RI; Zavoico, GB | 1 |
| Homma, Y; Ishitoya, J; Kato, M; Nagai, Y; Takenawa, T | 1 |
| Alexander, RW; Brock, TA; Ekstein, LS; Gimbrone, MA; Powers, CW; Rittenhouse, SE | 1 |
| Bauer, C; Bührle, C; Hackenthal, E; Hutter, A; Kurtz, A; Nobiling, R; Pfeilschifter, J; Taugner, R | 1 |
| Holmsen, H; Nilsen, AO; Rongved, S | 1 |
| Biden, TJ; Vallar, L; Wollheim, CB | 1 |
| Arthur, WL; O'Brian, CA; Weinstein, IB | 1 |
| Smith, CD; Snyderman, R; Uhing, RJ | 1 |
| Feinstein, MB; Halenda, SP | 1 |
| Banfic, HH; Divecha, N; Irvine, RF; Letcher, AJ; Rhee, SG | 1 |
| Dreux, C; Lods, JS; Morisset, J; Rossignol, B | 1 |
| Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ | 1 |
| Apgar, JR | 1 |
| Liedtke, CM | 1 |
| Pradayrol, L; Sarfati, PD; Scemama, JL; Seva, C; Vaysse, N | 1 |
| Smith, RD | 1 |
| Cohen, DA; Fitzpatrick, EA; Kaplan, AM | 1 |
| Gautero, H; Geny, B; Lecomte, MC; Lukowski, S; Marin, P; Mira, JP; Russo-Marie, F | 1 |
| Cantley, LC; Hartwig, JH; Janmey, PA; Kovacsovics, T; Kung, S; Stossel, TP; Toker, A | 1 |
| Babenko, NA; Krasil'nikova, OA | 1 |
| Gaudette, DC; Holub, BJ; Mani, I | 1 |
| Driessens, MH; Roos, E; Soede, RD; van Hulten, PE; van Rijthoven, EA | 1 |
| Hirokawa, K; Nariuchi, H; Tamura, T; Utsuyama, M; Wakikawa, A | 1 |
| Anderson, WB; Deng, J; Fukamachi, H; Kawakami, T; Kawakami, Y; Lehel, C; Ozawa, K; Suzuki, H; Yao, L | 1 |
| Ito, Y; Nakashima, S; Nozawa, Y | 1 |
| Homma, K; Imahori, K; Kanaho, Y; Kikkawa, U; Kuroda, S; Ohno, S; Takahashi, M; Yokozeki, T | 1 |
| King, LB; Monroe, JG; Norvell, A | 1 |
| Banno, Y; Fujita, H; Ito, Y; Kuzumaki, N; Nakashima, S; Nozawa, Y; Ono, Y | 1 |
| Fisher, SK; Linseman, DA; Sorensen, SD | 1 |
| D'Andrea, S; D'Santos, C; Divecha, N; Fernandez-Borga, M; Halstead, JR; Oomen, L; Roefs, M; Saqib, KM; Wakelam, MJ | 1 |
| Earnest, S; Feng, S; Hilgemann, DW; Lemmon, M; Mao, Y; Nasuhoglu, C; Shammat, I; Yamamato, M | 1 |
| Bragado, MJ; García-Marin, LJ; Jensen, RT; Pace, A; Tapia, JA | 1 |
| John, SA; Kodama, I; Lee, JK; Uozumi, N; Zhang, L | 1 |
| Padrón, D; Roth, MG; Tall, RD | 1 |
| Kirschner, MW; Lebensohn, AM; Pelish, HE; Peterson, JR | 1 |
| Cybulsky, AV; Le Berre, L; Lemay, S; Papillon, J; Takano, T | 1 |
| Herness, S; Zhao, FL | 1 |
| Chen, X; Du, X; Gao, H; Jia, C; Xu, J; Zhang, G; Zhang, H; Zhang, X | 1 |
| Jeong, JY; Kweon, HJ; Suh, BC | 1 |
| Chew, CY; Chung, TH; Lam, CH; Tan, KT; Wu, YP | 1 |
2 review(s) available for tetradecanoylphorbol acetate and glycerophosphoinositol 4,5-bisphosphate
| Article | Year |
|---|---|
Early response pattern analysis of the mitogenic pathway in lymphocytes and fibroblasts.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Cyclic AMP; DNA; Fibroblasts; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Mitogens; Mitosis; Oncogenes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Biosynthesis; Protein Kinase C; RNA; Sodium; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Energy requirements for stimulus-response coupling.
Topics: Adenosine Triphosphate; Blood Platelets; Calcium; Cytoplasm; Cytoplasmic Granules; Diglycerides; Humans; Phosphates; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1985 |
63 other study(ies) available for tetradecanoylphorbol acetate and glycerophosphoinositol 4,5-bisphosphate
| Article | Year |
|---|---|
Effect of staurosporine on fMet-Leu-Phe-stimulated human neutrophils: dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium.
Topics: Alkaloids; Calcium; Diglycerides; Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase D; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Vasopressin-stimulated [3H]-inositol phosphate and [3H]-phosphatidylbutanol accumulation in A10 vascular smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Glycerophospholipids; Hydrolysis; Indoles; Inositol 1,4,5-Trisphosphate; Mice; Muscle, Smooth, Vascular; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
Ca2+ and pH determine the interaction of chromaffin cell scinderin with phosphatidylserine and phosphatidylinositol 4,5,-biphosphate and its cellular distribution during nicotinic-receptor stimulation and protein kinase C activation.
Topics: Adrenal Medulla; Amiloride; Ammonium Chloride; Animals; Calcium; Cattle; Cells, Cultured; Enzyme Activation; Gelsolin; Hydrogen-Ion Concentration; Ionophores; Kinetics; Microfilament Proteins; Models, Biological; Nicotine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylserines; Phospholipids; Protein Kinase C; Receptors, Nicotinic; Tetradecanoylphorbol Acetate | 1992 |
Functionally diverse purinergic P2Y-receptors mediate prostanoid synthesis in cultured rat astrocytes: the role of ATP-induced phosphatidyl-inositol breakdown.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Cells, Cultured; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Prostaglandin D2; Prostaglandins; Rats; Receptors, Purinergic; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Phorbol ester inhibits 13-cis-retinoic acid-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in cultured murine keratinocytes: a possible negative feedback via protein kinase C-activation.
Topics: Animals; Animals, Newborn; Diglycerides; Enzyme Activation; Isotretinoin; Keratinocytes; Mice; Mice, Inbred BALB C; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of B cell proliferation with anti-CD19 monoclonal antibodies: anti-CD19 antibodies do not interfere with early signaling events triggered by anti-IgM or interleukin 4.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Calcimycin; Calcium; Cyclic AMP; DNA; Humans; In Vitro Techniques; Interleukin-4; Lymphocyte Activation; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The protein kinase C inhibitor, K252a, inhibits superoxide production in human neutrophils activated by both PIP2-dependent and -independent mechanisms.
Topics: Calcium; Carbazoles; Concanavalin A; Humans; Indole Alkaloids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Thrombin reverts the beta-adrenergic agonist-induced morphological response in rat glioma C6 cells.
Topics: Animals; Antithrombin III; Astrocytes; Blood; Calcium; Culture Media; Epithelial Cells; Glioma; Hirudins; Ionomycin; Isoproterenol; Microscopy, Electron, Scanning; Neomycin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Increased phospholipase C-catalyzed hydrolysis of phosphatidylinositol-4,5-bisphosphate and 1,2-sn-diacylglycerol content in psoriatic involved compared to uninvolved and normal epidermis.
Topics: Adult; Biopsy; Diglycerides; Epidermal Cells; Epidermis; Humans; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protease Inhibitors; Psoriasis; Reference Values; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Stimulation of the hydrolysis of phosphatidylinositol 4,5-bisphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts.
Topics: Animals; Cell Line; Choline; Endothelins; Fibroblasts; Hydrolysis; Inositol Phosphates; Kinetics; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate | 1990 |
Phorbol ester inhibits cholecystokinin octapeptide-induced amylase secretion and calcium mobilization, but is without effect on secretagogue-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in rabbit pancreatic acini.
Topics: Amylases; Animals; Calcium; Hydrolysis; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1987 |
Dual regulation by protein kinase C of the muscarinic response in Xenopus oocytes.
Topics: Acetylcholine; Animals; Calcium Radioisotopes; Diglycerides; Enzyme Activation; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ion Channels; Isomerism; Membrane Potentials; Oocytes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Xenopus laevis | 1989 |
Regulation of cytosolic pH in bovine parathyroid cells: effect of fluoride.
Topics: Amiloride; Animals; Calcium; Carrier Proteins; Cattle; Cytosol; Egtazic Acid; Ethers; GTP-Binding Proteins; Hydrogen-Ion Concentration; Ionomycin; Nigericin; Parathyroid Glands; Pertussis Toxin; Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Sodium Fluoride; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Plasma membrane associated phospholipase C from human platelets: synergistic stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by thrombin and guanosine 5'-O-(3-thiotriphosphate).
Topics: Blood Platelets; Cell Membrane; Drug Synergism; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Hydrolysis; In Vitro Techniques; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Thrombin; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons.
Topics: Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Chlorides; Cholera Toxin; Colforsin; Diglycerides; Fluorides; Ganglia, Spinal; GTP-Binding Proteins; Guanine Nucleotides; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Neurons, Afferent; Neuropeptide Y; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions.
Topics: Animals; Calcimycin; Calmodulin-Binding Proteins; Cyclosporins; Cytoplasmic Granules; Cytotoxicity, Immunologic; Exocytosis; Mast Cells; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1989 |
Endogenous phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol, and phosphatidic acid in stimulated human platelets.
Topics: Blood Platelets; Centrifugation; Chromatography, Thin Layer; Fatty Acids; Humans; Indicators and Reagents; Models, Theoretical; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipids; Tetradecanoylphorbol Acetate | 1989 |
Antibody-induced cAMP accumulation in splenocytes from athymic nude mice.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Colforsin; Cyclic AMP; Diglycerides; DNA Replication; Enzyme Activation; Mice; Mice, Nude; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Receptors, Antigen, B-Cell; Spleen; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of polyphosphoinositide turnover upon activation of protein kinases in human erythrocytes.
Topics: Adenosine Triphosphate; Cobra Neurotoxin Proteins; Cyclic AMP; Diterpenes; Enzyme Activation; Erythrocytes; Humans; Lipids; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Protein Kinases; Terpenes; Tetradecanoylphorbol Acetate; Trifluoperazine | 1988 |
Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages.
Topics: Calcimycin; Cells, Cultured; Diglycerides; Hydrolysis; Inositol Phosphates; Macrophages; Oxygen; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
The role of IP3, PKC, and pHi in the stimulus-response coupling of calfluxin-stimulated albumen glands of the freshwater snail Lymnaea stagnalis.
Topics: Animals; Antimony; Calcium; Cytosol; Female; Genitalia, Female; Histocytochemistry; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lymnaea; Microscopy, Electron; Mitochondria; Neuropeptides; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Epidermal growth factor (EGF) and hormones stimulate phosphoinositide hydrolysis and increase EGF receptor protein synthesis and mRNA levels in rat liver epithelial cells. Evidence for protein kinase C-dependent and -independent pathways.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cell Line; Enzyme Activation; Epidermal Growth Factor; Epinephrine; Epithelium; ErbB Receptors; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Liver; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester and phospholipase C-induced growth hormone secretion from pituitary somatotroph adenoma cells in culture: effects of somatostatin, bromocriptine, and pertussis toxin.
Topics: Adenoma; Bromocriptine; Cells, Cultured; Drug Interactions; Growth Hormone; GTP-Binding Proteins; Humans; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Pituitary Neoplasms; Protein Kinase C; Secretory Rate; Somatostatin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1987 |
Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils.
Topics: Animals; Diglycerides; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets.
Topics: Aminoquinolines; Blood Platelets; Calcimycin; Calcium; Humans; Lipid Metabolism; Phorbol Esters; Phorbols; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Role of enhanced inositol phospholipid metabolism in neutrophil activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Proteins; Calcimycin; Calcium; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.
Topics: Aminoquinolines; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Cytosol; Diglycerides; Enzyme Activation; Fluorescent Dyes; Glycerides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Muscle, Smooth, Vascular; Phorbols; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1985 |
Role of protein kinase C in inhibition of renin release caused by vasoconstrictors.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Diglycerides; Histocytochemistry; Kidney Glomerulus; Male; Microscopy, Phase-Contrast; Norepinephrine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Renin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Verapamil | 1986 |
Guanine nucleotides induce Ca2+-independent insulin secretion from permeabilized RINm5F cells.
Topics: Animals; Calcium; Cell Line; Cell Membrane Permeability; Cholera Toxin; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Insulin; Insulin Secretion; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1987 |
The activation of protein kinase C by the polyphosphoinositides phosphatidylinositol 4,5-diphosphate and phosphatidylinositol 4-monophosphate.
Topics: Animals; Brain; Calcium; Enzyme Activation; In Vitro Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1987 |
Nucleotide regulatory protein-mediated activation of phospholipase C in human polymorphonuclear leukocytes is disrupted by phorbol esters.
Topics: Calcium; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases; Virulence Factors, Bordetella | 1987 |
Phorbol myristate acetate stimulates formation of phosphatidyl inositol 4-phosphate and phosphatidyl inositol 4,5-bisphosphate in human platelets.
Topics: Blood Platelets; Humans; Kinetics; Phorbols; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Nucleus; Diglycerides; Dimethyl Sulfoxide; Erythrocytes; G1 Phase; Hemoglobins; Leukemia, Erythroblastic, Acute; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoric Diester Hydrolases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Phosphoinositide synthesis in desensitized rat pancreatic acinar cells.
Topics: Animals; Carbachol; Ceruletide; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol; Kinetics; Male; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tritium | 1995 |
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization.
Topics: Actins; Alkaloids; Animals; Biopolymers; Diglycerides; Dinitrophenols; Enzyme Activation; Immunologic Capping; Leukemia, Basophilic, Acute; Neoplasm Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Rats; Receptors, IgE; Serum Albumin, Bovine; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
The role of protein kinase C in alpha-adrenergic regulation of NaCl(K) cotransport in human airway epithelial cells.
Topics: Alkaloids; Arachidonic Acid; Carrier Proteins; Chlorides; Cystic Fibrosis; Diglycerides; Epinephrine; Epithelium; Humans; Isoproterenol; Methoxamine; Nasal Polyps; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoproteins; Protein Kinase C; Receptors, Adrenergic, alpha; Sodium Chloride Symporters; Staurosporine; Symporters; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1995 |
Coupling of pancreatic gastrin/cholecystokinin-B (G/CCKB) receptors to phospholipase C and protein kinase C in AR4-2J tumoral cells.
Topics: Alkaloids; Animals; Binding Sites; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Gastrins; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ornithine Decarboxylase; Pancreas; Pancreatic Neoplasms; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Rats; Receptors, Cholecystokinin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1994 |
Regulation of growth factor receptors on rat intestinal epithelial (RIE-1) cells by protein kinase C.
Topics: Angiotensin II; Animals; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Epithelium; ErbB Receptors; Hydrolysis; Intestines; Iodine Radioisotopes; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Rats; Receptors, Angiotensin; Receptors, Growth Factor; Tetradecanoylphorbol Acetate | 1994 |
Defective CD4+ T cell signaling in murine AIDS: uncoupling of the T cell receptor complex from PIP2 hydrolysis.
Topics: Animals; Calcium; CD28 Antigens; CD4-Positive T-Lymphocytes; Female; Inositol 1,4,5-Trisphosphate; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphotyrosine; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Inhibition of phospholipase D activity by fodrin. An active role for the cytoskeleton.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Calpain; Carrier Proteins; Cattle; Cytoskeleton; Enzyme Activation; Guanosine Triphosphate; HL-60 Cells; Humans; Microfilament Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phospholipases A; Signal Transduction; Spectrin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
D3 phosphoinositides and outside-in integrin signaling by glycoprotein IIb-IIIa mediate platelet actin assembly and filopodial extension induced by phorbol 12-myristate 13-acetate.
Topics: Actin Cytoskeleton; Actins; Androstadienes; Blood Platelets; Cytochalasin B; Enzyme Inhibitors; Gelsolin; Humans; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphotransferases (Alcohol Group Acceptor); Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 1996 |
[The role of thyroid hormones in the regulation of phosphatidic acid, phosphatidylinositol, and polyphosphoinositide synthesis in liver cells].
Topics: Animals; Liver; Male; Palmitic Acid; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Wistar; Sphingosine; Tetradecanoylphorbol Acetate; Thyroxine | 1996 |
Increased formation of phosphatidylinositol-4-phosphate in human platelets stimulated with lysophosphatidic acid.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Blood Platelets; Eicosanoids; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoxygenase Inhibitors; Lysophospholipids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1996 |
Activation of G-proteins with AIF-4 induces LFA-1-mediated adhesion of T-cell hybridoma cells to ICAM-1 by signal pathways that differ from phorbol ester- and manganese-induced adhesion.
Topics: Aluminum Compounds; Androstadienes; Animals; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fluorides; Genistein; GTP-Binding Proteins; Humans; Hybridomas; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lymphocyte Function-Associated Antigen-1; Maleimides; Manganese; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
Impairment of signal transduction in T cells from old mice.
Topics: Aging; Animals; Calcium; Clone Cells; Diglycerides; Inositol 1,4,5-Trisphosphate; Interleukin-2; Kinetics; Lymphocyte Activation; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphatidylinositol 4,5-Diphosphate; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Interactions between protein kinase C and pleckstrin homology domains. Inhibition by phosphatidylinositol 4,5-bisphosphate and phorbol 12-myristate 13-acetate.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blood Proteins; Cell Line; Mice; Molecular Sequence Data; Peptide Mapping; Phosphatidylinositol 4,5-Diphosphate; Phosphoproteins; Protein Binding; Protein Kinase C; Rats; Sequence Alignment; Tetradecanoylphorbol Acetate | 1997 |
Hydrogen peroxide-induced phospholipase D activation in rat pheochromocytoma PC12 cells: possible involvement of Ca2+-dependent protein tyrosine kinase.
Topics: Animals; Benzoquinones; Blotting, Western; Calcimycin; Calcium; Cinnamates; Enzyme Activation; Enzyme Inhibitors; Genistein; Hydrogen Peroxide; Isoflavones; Lactams, Macrocyclic; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sulfides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Phosphatidic acid-dependent phosphorylation of a 29-kDa protein by protein kinase Calpha in bovine brain cytosol.
Topics: Animals; Brain; Brain Chemistry; Calcium; Carcinogens; Cattle; Chelating Agents; Cytosol; Egtazic Acid; Isoenzymes; Nerve Tissue Proteins; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate | 1998 |
Antigen receptor-induced signal transduction imbalances associated with the negative selection of immature B cells.
Topics: Animals; Apoptosis; B-Lymphocytes; Mice; Mice, Inbred BALB C; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin.
Topics: 3T3 Cells; Animals; Bradykinin; Calcimycin; Cell Membrane; DNA, Complementary; Egtazic Acid; Enzyme Activation; Gelsolin; Humans; Isoenzymes; Kinetics; Lysophospholipids; Mice; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-epsilon; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate.
Topics: Androstadienes; Animals; Arsenicals; Cell Adhesion Molecules; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Myosin-Light-Chain Kinase; Neuroblastoma; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphoinositide-3 Kinase Inhibitors; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Cholinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1999 |
Interaction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activity.
Topics: Animals; Aorta; Cells, Cultured; COS Cells; Endothelium, Vascular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, Reporter; Immunohistochemistry; Mice; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein Binding; Recombinant Fusion Proteins; Sequence Deletion; Swine; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Modulation of cardiac PIP2 by cardioactive hormones and other physiologically relevant interventions.
Topics: Adenosine; Animals; Cells, Cultured; Diglycerides; Electric Conductivity; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; Heart Ventricles; Hormones; Hypertonic Solutions; Myocardium; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Sarcolemma; Tetradecanoylphorbol Acetate | 2002 |
Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.
Topics: Animals; Binding Sites; Calcium; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Hydrolysis; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 2003 |
Mechanosensitivity of GIRK channels is mediated by protein kinase C-dependent channel-phosphatidylinositol 4,5-bisphosphate interaction.
Topics: Amino Acid Sequence; Animals; Cytosol; Enzyme Inhibitors; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Green Fluorescent Proteins; Hydrolysis; Luminescent Proteins; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis; Naphthalenes; Oocytes; Osmosis; Phosphatidylinositol 4,5-Diphosphate; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Rabbits; RNA, Complementary; Spectrometry, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Xenopus; Xenopus laevis | 2004 |
Phospholipase D2 is required for efficient endocytic recycling of transferrin receptors.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Cell Membrane; Endocytosis; Endosomes; Gene Expression Regulation; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Nerve Tissue Proteins; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); rab GTP-Binding Proteins; Receptors, Transferrin; RNA Interference; Tetradecanoylphorbol Acetate | 2006 |
Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components.
Topics: Actin-Related Protein 2-3 Complex; Actins; Animals; cdc42 GTP-Binding Protein; Cell Surface Extensions; Drug Evaluation, Preclinical; Female; Guanine Nucleotide Dissociation Inhibitors; In Vitro Techniques; Oocytes; Phosphatidylinositol 4,5-Diphosphate; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Xenopus laevis | 2006 |
Role of phosphatidylinositol 4,5-bisphosphate in the activation of cytosolic phospholipase A2-alpha.
Topics: Animals; Arachidonic Acids; Base Sequence; Binding Sites; Calcimycin; Calcium; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytosol; Enzyme Activation; Epidermal Growth Factor; Group IV Phospholipases A2; Ionophores; Isoenzymes; Membrane Lipids; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C delta; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandins; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2006 |
Resynthesis of phosphatidylinositol 4,5-bisphosphate mediates adaptation of the caffeine response in rat taste receptor cells.
Topics: Androstadienes; Animals; Benzylamines; Caffeine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chromones; Delayed Rectifier Potassium Channels; Enzyme Inhibitors; Estrenes; Male; Morpholines; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C beta; Polylysine; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sulfonamides; Taste; Taste Buds; Tetradecanoylphorbol Acetate; Wortmannin | 2009 |
Membrane depolarization increases membrane PtdIns(4,5)P2 levels through mechanisms involving PKC βII and PI4 kinase.
Topics: Animals; Carcinogens; Humans; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Membrane Potentials; Minor Histocompatibility Antigens; Phosphatidylinositol 4,5-Diphosphate; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein Kinase C beta; Rats; RNA Interference; Tetradecanoylphorbol Acetate; Xenopus laevis; Xenopus Proteins | 2011 |
Dual Regulation of R-Type CaV2.3 Channels by M1 Muscarinic Receptors.
Topics: Animals; Calcium Channels, R-Type; Cell Membrane; Gene Expression Regulation; HEK293 Cells; Humans; Membrane Potentials; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Receptor, Muscarinic M1; Tetradecanoylphorbol Acetate; Zebrafish; Zebrafish Proteins | 2016 |
Imaging and Quantification of Secreted Peroxynitrite at the Cell Surface by a Streptavidin-Biotin-Controlled Binding Probe.
Topics: Animals; Biotin; Carbocyanines; Cell Membrane; Enzyme Activators; Fluorescent Dyes; Gene Expression; Interferon-gamma; Lipopolysaccharides; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Phosphatidylinositol 4,5-Diphosphate; RAW 264.7 Cells; Streptavidin; Tetradecanoylphorbol Acetate | 2018 |