tetradecanoylphorbol acetate has been researched along with glucagon in 105 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (38.10) | 18.7374 |
| 1990's | 58 (55.24) | 18.2507 |
| 2000's | 5 (4.76) | 29.6817 |
| 2010's | 2 (1.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez, A; Boscá, L; Cascales, M; Diez Fernández, C; Martin-Sanz, P; Sanchez-Pérez, M | 1 |
| Brubaker, PL; Stobie-Hayes, KM | 1 |
| Dettmer, D; Hermsdorf, T | 1 |
| Brubaker, PL; Lévesque, L; Sun, AM | 1 |
| Houslay, MD; Tang, EK | 1 |
| Gardemann, A; Jungermann, K; Seseke, FG | 1 |
| Grapengiesser, E; Gylfe, E; Hellman, B | 1 |
| Garcia-Ruiz, C; Kaplowitz, N; Kuhlenkamp, J; Lu, SC | 1 |
| Higashi, K; Hoek, JB | 2 |
| Hreniuk, S; LaNoue, KF; Scaduto, RC; Sterniczuk, A | 1 |
| Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H | 1 |
| Gustafsson, JA; Legraverend, C; Mode, A; Tollet, P | 1 |
| Buszkowska, M; Famulski, KS; Latos, P; Wojtczak, AB | 1 |
| Fain, JN; Pittner, RA | 2 |
| Kiekens, R; Pipeleers, DG; Schuit, FC | 1 |
| Bushfield, M; Houslay, MD; Lavan, BE | 1 |
| Bhathena, S; Powell, AM; Recant, L; Solomon, D; Timmers, KI; Voyles, NR; Wilkins, SD | 1 |
| Demigne, C; Morand, C; Redon, C; Remesy, C | 1 |
| Rösler, M; Schoner, W | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Hruby, VJ; Macías-Silva, M; Torres-Márquez, ME; Trivedi, D | 1 |
| Chan, SO; Wong, SS; Yeung, DC | 1 |
| Banerjee, DK; Oliveira, CM | 1 |
| Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK | 1 |
| Blackmore, PF; Exton, JH | 1 |
| Houslay, MD; Irvine, F; Pyne, NJ | 1 |
| Houslay, MD; Milligan, G; Murphy, GJ; Pyne, NJ | 1 |
| Augert, G; Blackmore, PF; Bocckino, SB; Exton, JH | 1 |
| Baba, S; Ohki, A; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Bijleveld, C; Geelen, MJ; Vaartjes, WJ | 1 |
| Contreras-Rodríguez, JL; García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M | 1 |
| Dettmer, D; Hermsdorf, T; Hofmann, E | 1 |
| Beckner, SK; Darfler, FJ; Lin, MC | 1 |
| Fukui, H; Horio, Y; Taketoshi, M; Tanaka, T; Wada, H | 1 |
| Ishikawa, S; Okada, K; Saito, T | 1 |
| Capito, K; Hedeskov, CJ; Thams, P | 1 |
| Iyengar, R; Premont, RT | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M; Plebañski, M | 1 |
| Coll, KE; Filburn, C; Hansen, CA; Johanson, R; Verhoeven, A; Williamson, JR; Williamson, MT | 1 |
| Bjaaland, T; Hii, CS; Howell, SL; Jones, PM | 1 |
| Bjaaland, T; Howell, SL; Jones, PM | 1 |
| Chiba, T; Chihara, K; Fujita, T; Fukase, M; Kadowaki, S; Yamatani, T | 1 |
| Drucker, DJ; Habener, JF; Philippe, J | 1 |
| Fukusen, N; Katunuma, N; Kido, H | 1 |
| Blackmore, PF; Bocckino, SB; Charest, R; Exton, JH; Lynch, CJ | 1 |
| Gawler, DJ; Heyworth, CM; Houslay, MD; Wilson, SP | 1 |
| Kumae, S; Ono, J; Sato, Y; Takaki, R | 1 |
| Hansford, RG; Staddon, JM | 3 |
| Hii, CS; Howell, SL | 2 |
| Amiel, C; Friedlander, G | 1 |
| Allan, CJ; Hruby, VJ; Hussin, AH; Skett, P | 1 |
| Bouscarel, B; Decker, C; Exton, JH; Meurer, K | 1 |
| Casteleijn, E; Kamps, JA; Koster, JF; Kuiper, J; Van Berkel, TJ; Van Rooij, HC | 1 |
| Blackmore, PF; Bocckino, SB; Exton, JH; Lynch, CJ | 1 |
| Hii, CS; Howell, SL; Stutchfield, J | 1 |
| Harano, Y; Kojima, H; Kosugi, K; Nakano, T; Shigeta, Y | 1 |
| Blackmore, PF; Charest, R; Exton, JH | 1 |
| Blackmore, PF; Bocckino, SB; Exton, JH | 1 |
| Eilen, SD; Shah, SV; Wallin, JD | 1 |
| Heyworth, CM; Houslay, MD; Kinsella, AR; Whetton, AD | 1 |
| Kachra, Z; Posner, BI; Yang, CR | 1 |
| Kachra, Z; Murphy, LJ; Posner, BI; Yang, CR | 1 |
| Brubaker, PL; Rocca, AS | 1 |
| Fujimoto, Y; Inagami, M; Kimura, K; Moriyama, M; Shiota, M; Sugano, T | 1 |
| Alvaro, D; Bini, A; Capocaccia, L; Della Guardia, P; Furfaro, S; Gigliozzi, A; La Rosa, T; Piat, C | 1 |
| Eikvar, L; Eskild, W; Hansson, V; Taskén, KA | 1 |
| Abello, J; Bosshard, A; Chayvialle, JA; Saifia, S | 1 |
| Bouscarel, B; Dubner, H; Fromm, H; Gettys, TW | 1 |
| Agius, L; Beresford, GW | 2 |
| Bushfield, M; Houslay, MD; Lavan, BE; Morris, NJ | 1 |
| Funai, T; Ichiyama, A; Oda, T; Ohbayashi, K; Uchida, C | 1 |
| Abello, J; Bernard, C; Bosshard, A; Chayvialle, JA; Cuber, JC; Ye, F | 1 |
| Beil, W; Muallem, R; Odes, HS; Reimer, R; Schwenk, M; Sewing, KF | 1 |
| Jungermann, K; Miura, H; Neuschäfer-Rube, F; Püschel, GP | 1 |
| Meijer, DK; Merema, M; Nijholt, A; Smit, H; Steen, H | 1 |
| Jungermann, K; Kirchner, C; Püschel, GP; Schröder, A | 1 |
| Daneschmand, H; Klein, H; Probst, I; Quentmeier, A; Unthan-Fechner, K | 1 |
| Corbett, JA; Marshall, CA; McDaniel, ML; Wang, JL | 1 |
| De Wulf, H; Keppens, S; Vandekerckhove, A | 1 |
| Gespach, CP; Hanson, PJ; McKenna, P; Williams, JM | 1 |
| Buggy, JJ; Heurich, RO; Rossomando, AJ; Vandenberg, MT | 1 |
| Dolci, W; Thorens, B; Widmann, C | 1 |
| Grapengiesser, E; Gylfe, E; Hellman, B; Liu, YJ | 1 |
| Deeg, MA; Verchere, CB | 1 |
| Ding, WG; Gromada, J | 1 |
| Blume, R; Fürstenau, U; Kennerknecht, I; Knepel, W; Schwaninger, M | 1 |
| Connell, JM; Houslay, MD; Rozengurt, E; Tobias, ES | 1 |
| Buchan, AM; Damholt, AB; Kofod, H | 1 |
| Benito, E; Blazquez, E; Bosch, MA | 1 |
| Abello, J; Bosshard, A; Chayvialle, JA; Chevrier, AM; Cuber, JC; Saïfia, S | 1 |
| Prentki, M; Roche, E; Schlegel, W; Susini, S | 1 |
| Brubaker, PL; Drucker, DJ; Schloos, J | 1 |
| Akesson, B; Lundquist, I | 1 |
| Aust, G; Nguyen, TB; Scherbaum, WA; Seissler, J; Steinbrenner, H | 1 |
| Cerasi, E; Efendic, S; Kaiser, N; Khan, A; Nesher, R; Warwar, N | 1 |
| Bosco, D; Gonelle-Gispert, C; Halban, PA; Rouiller, DG; Wollheim, CB | 1 |
| Anini, Y; Brubaker, PL | 1 |
| Bouscarel, B; Chapin-Kennedy, K; Ikegami, T; Krilov, L; Meng, J; Patel, B | 1 |
| Amisten, S; De Marinis, YZ; Eliasson, L; Renström, E; Rorsman, P; Taneera, J; Zhang, E | 1 |
| Fukui, H; Kobayashi, M; Mizuguchi, H; Sato, Y; Tamaki, M; Tokashiki, N; Yamamoto, K; Yamauchi, A | 1 |
2 review(s) available for tetradecanoylphorbol acetate and glucagon
| Article | Year |
|---|---|
Effects of alcohol on polyphosphoinositide-mediated intracellular signaling.
Topics: Animals; Cells, Cultured; Enzyme Activation; Ethanol; Glucagon; Insulin; Ionomycin; Kinetics; Liver; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasopressins | 1991 |
Mechanisms involved in receptor-mediated changes of intracellular Ca2+ in liver.
Topics: Animals; Calcium; Glucagon; Humans; Inositol Phosphates; Liver; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
103 other study(ies) available for tetradecanoylphorbol acetate and glucagon
| Article | Year |
|---|---|
Isoenzymes of carbohydrate metabolism in primary cultures of hepatocytes from thioacetamide-induced rat liver necrosis: responses to growth factors.
Topics: Animals; Bombesin; Carbohydrate Metabolism; Cells, Cultured; Fetus; Fructosediphosphates; Glucagon; Growth Substances; Insulin; Isoenzymes; Liver; Liver Glycogen; Male; Necrosis; Phosphofructokinase-2; Phosphorylase a; Phosphotransferases; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thioacetamide | 1992 |
Control of proglucagon-derived peptide synthesis and secretion in fetal rat hypothalamus.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Enzyme Activation; Fetal Proteins; Glucagon; Hypothalamus; Neuropeptides; Proglucagon; Protein Kinase C; Protein Kinases; Protein Precursors; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate | 1992 |
Phorbol ester effects on hormonal responses in freshly isolated short-term incubated and cultured hepatocytes.
Topics: Animals; Glucagon; Glucose; In Vitro Techniques; Isoproterenol; Liver; Male; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Maintenance of long-term secretory function by microencapsulated islets of Langerhans.
Topics: 1-Methyl-3-isobutylxanthine; Alginates; Animals; Biocompatible Materials; Enzyme Activation; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membranes, Artificial; Polylysine; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Glucagon, vasopressin and angiotensin all elicit a rapid, transient increase in hepatocyte protein kinase C activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Cell Membrane; Cells, Cultured; Cytosol; Enzyme Activation; Glucagon; Kinetics; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
Signal propagation via gap junctions, a key step in the regulation of liver metabolism by the sympathetic hepatic nerves.
Topics: Alcohols; Animals; Carbenoxolone; Cell Communication; Dinoprost; Glucagon; Glucose; Heptanol; Intercellular Junctions; Liver; Liver Regeneration; Male; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tetradecanoylphorbol Acetate | 1992 |
Glucose sensing of individual pancreatic beta-cells involves transitions between steady-state and oscillatory cytoplasmic Ca2+.
Topics: Animals; Calcium; Glucagon; Glucose; Islets of Langerhans; Mice; Tetradecanoylphorbol Acetate | 1992 |
Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.
Topics: Animals; Bucladesine; Cells, Cultured; Cytosol; Down-Regulation; Glucagon; Glutathione; In Vitro Techniques; Liver; Male; Perfusion; Phenylephrine; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
The mechanism of Ca2(+)-related control of gluconeogenesis in perfused liver.
Topics: Animals; Aspartic Acid; Biological Transport; Calcium; Glucagon; Gluconeogenesis; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Phenylephrine; Rats; Tetradecanoylphorbol Acetate | 1991 |
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
A role for protein kinases in the growth hormone regulation of cytochrome P4502C12 and insulin-like growth factor-I messenger RNA expression in primary adult rat hepatocytes.
Topics: Alkaloids; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Diglycerides; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Effect of glucagon and phorbol myristate acetate on oxidative demethylation and lipid peroxidation in isolated hepatocytes.
Topics: Aminopyrine; Animals; Benzene Derivatives; Cells, Cultured; Cytochrome P-450 Enzyme System; Glucagon; Lipid Peroxidation; Liver; Male; Methylation; Microsomes, Liver; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Ethanol causes desensitization of receptor-mediated phospholipase C activation in isolated hepatocytes.
Topics: Angiotensin II; Animals; Calcium; Enzyme Activation; Epidermal Growth Factor; Ethanol; Glucagon; Liver; Male; Phenylephrine; Phosphatidylinositol Phosphates; Phosphatidylinositols; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasopressins | 1991 |
Activation of membrane protein kinase C by glucagon and Ca(2+)-mobilizing hormones in cultured rat hepatocytes. Role of phosphatidylinositol and phosphatidylcholine hydrolysis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Calcimycin; Cell Membrane; Cells, Cultured; Enzyme Activation; Glucagon; Hydrolysis; Inositol Phosphates; Kinetics; Liver; Myristic Acid; Myristic Acids; Norepinephrine; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Measuring the balance between insulin synthesis and insulin release.
Topics: Animals; Epinephrine; Glucagon; Glucose; Histidine; Homeostasis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Proinsulin; Protein Biosynthesis; Rats; Tetradecanoylphorbol Acetate; Tyrosine | 1991 |
Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cells, Cultured; Ethers, Cyclic; Glucagon; GTP-Binding Proteins; Ionophores; Kinetics; Liver; Macromolecular Substances; Male; Okadaic Acid; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Multiple alterations in insulin responses to glucose in islets from 48-h glucose-infused nondiabetic rats.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Drug Hypersensitivity; Glucagon; Glucose; Glyceraldehyde; Glycerides; Infusions, Intravenous; Insulin; Islets of Langerhans; Keto Acids; Male; Mannoheptulose; Rats; Rats, Inbred Strains; Somatostatin; Temperature; Tetradecanoylphorbol Acetate; Tolbutamide; Verapamil | 1990 |
Vasopressin and norepinephrine stimulation of inositol phosphate accumulation in rat hepatocytes are modified differently by protein f1nase C and protein kinase A.
Topics: Animals; Calcimycin; Cells, Cultured; Glucagon; Inositol Phosphates; Liver; Norepinephrine; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Non-hormonal and hormonal control of glycogen metabolism in isolated sheep liver cells.
Topics: Animals; Drug Interactions; Egtazic Acid; Enzyme Activation; Epinephrine; Fructose; Glucagon; Glucose; Glycogen; Glycogen Synthase; Insulin; Liver; Phenylephrine; Phosphorylase a; Propionates; Sheep; Tetradecanoylphorbol Acetate | 1990 |
Antagonizing effects of phorbol 12-myristate 13-acetate on hormonally stimulated gluconeogenesis in isolated rat hepatocytes involve activity changes of pyruvate kinase.
Topics: Animals; Bucladesine; Cells, Cultured; Epinephrine; Glucagon; Gluconeogenesis; Lactates; Liver; Male; Protein Kinase C; Pyruvate Kinase; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1990 |
Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism.
Topics: Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Glucagon; Hypothyroidism; Liver; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Urea | 1990 |
Regulation of Ki-ras expression in Reuber H35 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Diglycerides; DNA Probes; Egtazic Acid; Gene Expression Regulation, Neoplastic; Genes, ras; Glucagon; Isoquinolines; Kinetics; Liver Neoplasms, Experimental; Piperazines; Protein Kinase Inhibitors; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Role of extracellular signaling on endothelial cell proliferation and protein N-glycosylation.
Topics: Animals; Cattle; Cell Division; Endothelium, Vascular; Glucagon; Glycoproteins; Glycosylation; Heparin; Insulin; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thyroxine | 1990 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate | 1986 |
Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Aluminum; Aluminum Compounds; Angiotensin II; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Fluorides; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Pertussis Toxin; Phorbols; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Vasopressins; Virulence Factors, Bordetella | 1986 |
The phorbol ester TPA inhibits cyclic AMP phosphodiesterase activity in intact hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic AMP; Drug Synergism; Glucagon; Liver; Male; Rats; Tetradecanoylphorbol Acetate | 1986 |
Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi.
Topics: Adenylyl Cyclases; Animals; Antigen-Antibody Complex; Cells, Cultured; Glucagon; GTP-Binding Proteins; Immune Sera; Kinetics; Liver; Male; Phosphorylation; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Egtazic Acid; Epinephrine; Fatty Acids; Glucagon; Glycerides; Hormones; Kinetics; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1989 |
Increased beta-cell secretory responsiveness to ceruletide and TPA in streptozocin-induced mildly diabetic rats.
Topics: Animals; Arginine; Carbachol; Ceruletide; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Streptozocin; Tetradecanoylphorbol Acetate | 1989 |
Time course of hormonal effects on acetyl-CoA carboxylase as measured in digitonin-permeabilized rat hepatocytes.
Topics: Acetyl-CoA Carboxylase; Animals; Cell Membrane Permeability; Cells, Cultured; Digitonin; Fatty Acids; Glucagon; Hormones; Insulin; Ligases; Liver; Male; Norepinephrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Effect of H-7 on the modulation of glucagon actions by activators of protein kinase-C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine Vasopressin; Cells, Cultured; Drug Interactions; Female; Glucagon; Hypothyroidism; Isoquinolines; Liver; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Urea | 1989 |
Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Female; Fetus; Glucagon; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Induction of glucagon sensitivity in a transformed kidney cell line by prostaglandin E2 and its inhibition by epidermal growth factor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood; Cell Differentiation; Cell Line, Transformed; Cyclic AMP; Dinoprostone; Dogs; Epidermal Growth Factor; Glucagon; Kidney; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate | 1987 |
Induction of cytosolic aspartate aminotransferase by glucagon in primary cultured rat hepatocytes.
Topics: Animals; Aspartate Aminotransferases; Bucladesine; Calcimycin; Cells, Cultured; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Glucagon; Insulin; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Arginine vasopressin increases cellular free calcium concentration and adenosine 3',5'-monophosphate production in rat renal papillary collecting tubule cells in culture.
Topics: Animals; Arginine Vasopressin; Bucladesine; Calcium; Calcium Radioisotopes; Cells, Cultured; Colforsin; Cyclic AMP; Egtazic Acid; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Stimulation by glucose of cyclic AMP accumulation in mouse pancreatic islets is mediated by protein kinase C.
Topics: Animals; Antibodies; Carbachol; Cyclic AMP; Glucagon; Glucose; In Vitro Techniques; Islets of Langerhans; Male; Mice; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1988 |
Glucagon-induced desensitization of adenylyl cyclase in primary cultures of chick hepatocytes. Evidence for multiple pathways.
Topics: Adenylyl Cyclases; Alprostadil; Angiotensin II; Animals; Cells, Cultured; Chickens; Cycloheximide; Glucagon; Isoproterenol; Kinetics; Liver; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
Role of protein kinase C in arginine-induced glucagon secretion from isolated rat islets of Langerhans.
Topics: Animals; Arginine; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Glucagon; Langerhans Cells; Protein Kinase C; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Role of intracellular mediators in glucagon secretion: studies using intact and electrically permeabilized rat islets of Langerhans.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Cell Membrane Permeability; Cyclic AMP; Electricity; Glucagon; In Vitro Techniques; Islets of Langerhans; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1988 |
12-O-tetradecanoyl phorbol-13-acetate (TPA) stimulates somatostatin release from isolated perfused rat stomach.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Mucosa; Glucagon; In Vitro Techniques; Kinetics; Male; Perfusion; Phorbols; Rats; Rats, Inbred Strains; Somatostatin; Tetradecanoylphorbol Acetate | 1985 |
Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway.
Topics: Angiotensinogen; Animals; Bucladesine; Cell Line; Diglycerides; Enzyme Activation; Glucagon; Hydrocortisone; Insulin; Islets of Langerhans; Protein Kinase C; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1987 |
Tumor-promoting phorbol ester amplifies the inductions of tyrosine aminotransferase and ornithine decarboxylase by glucocorticoid.
Topics: Adrenalectomy; Animals; Dexamethasone; Drug Synergism; Enzyme Induction; Glucagon; Insulin; Kinetics; Male; Ornithine Decarboxylase; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tyrosine Transaminase | 1987 |
Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Phentolamine; Phorbols; Phosphorylase a; Propranolol; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Time Factors; Vasopressins | 1985 |
The phorbol ester TPA prevents the expression of both glucagon desensitisation and the glucagon-mediated block of insulin stimulation of the peripheral plasma membrane cyclic AMP phosphodiesterase in rat hepatocytes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Cell Membrane; Drug Interactions; Glucagon; In Vitro Techniques; Insulin; Liver; Male; Phorbols; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Effect of phorbol esters on glucagon secretion from a glucagon-secreting clonal cell line. Synergistic effects of A23187 and theophylline.
Topics: Adenoma, Islet Cell; Animals; Calcimycin; Cell Line; Clone Cells; Cricetinae; Drug Synergism; Glucagon; In Vitro Techniques; Insulinoma; Pancreatic Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Theophylline | 1986 |
4 beta-Phorbol 12-myristate 13-acetate attenuates the glucagon-induced increase in cytoplasmic free Ca2+ concentration in isolated rat hepatocytes.
Topics: Aminoquinolines; Animals; Bucladesine; Calcium; Colforsin; Fluorescent Dyes; Glucagon; In Vitro Techniques; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Role of second messengers in the regulation of glucagon secretion from isolated rat islets of Langerhans.
Topics: Animals; Arginine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Diglycerides; Drug Interactions; Glucagon; Glycerides; Islets of Langerhans; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
Protein kinase C activators and bradykinin selectively inhibit vasopressin-stimulated cAMP synthesis in MDCK cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Glucagon; Isoquinolines; Piperazines; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
The effects of glucagon and TH-glucagon on steroid metabolism in isolated rat hepatocytes.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Calcimycin; Cells, Cultured; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1988 |
The role of protein kinase C in the inactivation of hepatic glycogen synthase by calcium-mobilizing agonists.
Topics: Adenosine Triphosphate; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Glucagon; Glycogen Synthase; Isoproterenol; Liver; Male; Phosphorylases; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester.
Topics: Animals; Aspirin; Drug Synergism; Glucagon; Glucose; In Vitro Techniques; Liver; Liver Glycogen; Male; Prostaglandin D2; Prostaglandins D; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1988 |
The activation of pyruvate dehydrogenase by glucagon in hepatocytes is diminished by phorbol myristate acetate: a role for cytoplasmic calcium in dehydrogenase regulation.
Topics: Animals; Calcium; Cells, Cultured; Cytosol; Enzyme Activation; Glucagon; Homeostasis; Kinetics; Liver; Pyruvate Dehydrogenase Complex; Rats; Tetradecanoylphorbol Acetate | 1988 |
Calcium-mobilizing hormones and phorbol myristate acetate mediate heterologous desensitization of the hormone-sensitive hepatic Na+/K+ pump.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Biological Transport, Active; Calcium; Epinephrine; Glucagon; Hormones; Liver; Male; Monensin; Potassium; Rats; Sodium; Tetradecanoylphorbol Acetate | 1987 |
Enhancement of glucagon secretion from isolated rat islets of Langerhans by phorbol 12-myristate 13-acetate.
Topics: Animals; Calcium; Glucagon; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Phorbols; Rats; Rats, Inbred Strains; Temperature; Tetradecanoylphorbol Acetate | 1986 |
Restoration of the A cell response to glucose in isolated rat islets of Langerhans.
Topics: Animals; Arginine; Colforsin; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
The glucagon-induced activation of pyruvate dehydrogenase in hepatocytes is diminished by 4 beta-phorbol 12-myristate 13-acetate. A role for cytoplasmic Ca2+ in dehydrogenase regulation.
Topics: Animals; Arginine Vasopressin; Calcium; Cytoplasm; Enzyme Activation; Glucagon; In Vitro Techniques; Liver; Male; NADP; Phenylephrine; Pyruvate Dehydrogenase Complex; Pyruvate Kinase; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
A suppressive role of c-kinase for the stimulation of hepatic ketogenesis by glucagon and epinephrine.
Topics: Animals; Carnitine O-Palmitoyltransferase; Diglycerides; Enzyme Activation; Epinephrine; Glucagon; Ketone Bodies; Liver; Male; Palmitic Acid; Palmitic Acids; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1986 |
Characterization of responses of isolated rat hepatocytes to ATP and ADP.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Enzyme Activation; Glucagon; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Male; Phosphorylase a; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Calcium; Cell Membrane; Chromatography, High Pressure Liquid; Diglycerides; Egtazic Acid; Epinephrine; Fatty Acids; Glucagon; Glycerides; Kinetics; Liver; Male; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Chemiluminescence and superoxide anion production by leukocytes from diabetic patients.
Topics: Adult; Aged; Anions; Diabetes Mellitus; Glucagon; Humans; Kinetics; Luminescent Measurements; Middle Aged; Neutrophils; Opsonin Proteins; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
The phorbol ester, TPA inhibits glucagon-stimulated adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Cyclic AMP; Diglycerides; Glucagon; Guanylyl Imidodiphosphate; Liver; Male; Phorbols; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1984 |
The augmentation of insulin-like growth factor-I messenger ribonucleic acid in cultured rat hepatocytes: activation of protein kinase-A and -C is necessary, but not sufficient.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Blotting, Northern; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Drug Synergism; Enzyme Activation; Glucagon; Growth Hormone; Insulin-Like Growth Factor I; Isoquinolines; Kinetics; Liver; Male; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
The regulation of insulin-like growth factor-binding protein 1 messenger ribonucleic acid in cultured rat hepatocytes: the roles of glucagon and growth hormone.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Carrier Proteins; Cells, Cultured; Cyclic AMP; Densitometry; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Glucagon; Growth Hormone; Insulin-Like Growth Factor Binding Protein 1; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures.
Topics: Animals; Cells, Cultured; Fatty Acids; Female; Fetus; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Peptide Fragments; Pregnancy; Proglucagon; Protein Kinase C; Protein Precursors; Rats; Rats, Wistar; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1995 |
Cold acclimation induces zonal heterogeneity in gluconeogenic responses to glucagon in rat liver lobule.
Topics: Acclimatization; Animals; Bucladesine; Calcimycin; Cells, Cultured; Cold Temperature; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glutamate-Ammonia Ligase; Kinetics; Liver; Male; Norepinephrine; Phosphoenolpyruvate Carboxykinase (GTP); Phosphofructokinase-1; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.
Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides | 1995 |
Protein kinase C activation and positive and negative agonist regulation of 3',5'-cyclic adenosine monophosphate levels in cultured rat Sertoli cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Follicle Stimulating Hormone; Glucagon; Isoproterenol; Male; Phenylisopropyladenosine; Protein Kinase C; Rats; Sertoli Cells; Tetradecanoylphorbol Acetate | 1993 |
[Secretion of peptide YY and truncated glucagon-like peptide 1 by isolated intestinal cells in rats].
Topics: Adult; Animals; Calcium-Transporting ATPases; Chromatography, Affinity; Glucagon; Glucagon-Like Peptide 1; Humans; Intestinal Mucosa; Ionomycin; Male; Peptide Fragments; Peptide YY; Peptides; Phorbols; Protein Precursors; Rats; Rats, Wistar; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Ursodeoxycholic acid inhibits glucagon-induced cAMP formation in hamster hepatocytes: a role for PKC.
Topics: Angiotensin II; Animals; Bile Acids and Salts; Calcium; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Glucagon; Liver; Male; Mesocricetus; Protein Kinase C; Receptors, Glucagon; Tetradecanoylphorbol Acetate; Ursodeoxycholic Acid | 1995 |
Epidermal growth factor counteracts insulin-induced expression of glucokinase in hepatocytes.
Topics: Animals; Cells, Cultured; Epidermal Growth Factor; Gene Expression; Glucagon; Glucokinase; Glucosephosphate Dehydrogenase; Insulin; Insulin Antagonists; Kinetics; Liver; Male; Phospholipase D; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Multi-site phosphorylation of the inhibitory guanine nucleotide regulatory protein Gi-2 occurs in intact rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Colforsin; Glucagon; GTP-Binding Proteins; Immunosorbent Techniques; Isoelectric Point; Liver; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trypsin; Vasopressins | 1994 |
Epidermal growth factor counteracts the insulin induced expression of glucokinase in hepatocytes.
Topics: Animals; Cells, Cultured; Epidermal Growth Factor; Gene Expression; Glucagon; Glucokinase; Insulin; Insulin Antagonists; Kinetics; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Regulation by glucagon of serine: pyruvate/alanine: glyoxylate aminotransferase gene expression in cultured rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine Transaminase; Animals; Calcimycin; Cells, Cultured; Cycloheximide; Dexamethasone; Enzyme Induction; Gene Expression; Glucagon; In Vitro Techniques; Liver; Male; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Transaminases; Transcription, Genetic | 1994 |
Stimulation of glucagon-like peptide-1 secretion by muscarinic agonist in a murine intestinal endocrine cell line.
Topics: Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Endocrine Glands; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Intestines; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Parasympathomimetics; Peptide Fragments; Protein Precursors; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate | 1994 |
Role of carbonic anhydrase in basal and stimulated bicarbonate secretion by the guinea pig duodenum.
Topics: Acetazolamide; Animals; Bicarbonates; Bucladesine; Carbachol; Carbonic Anhydrases; Dibutyryl Cyclic GMP; Dinoprostone; Duodenum; Glucagon; Guinea Pigs; Male; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1994 |
Inhibition by the protein kinase C activator 4 beta-phorbol 12-myristate 13-acetate of the prostaglandin F2 alpha-mediated and noradrenaline-mediated but not glucagon-mediated activation of glycogenolysis in rat liver.
Topics: Aluminum Compounds; Animals; Dinoprost; Enzyme Activation; Fluorides; Glucagon; Glucose; Glycogen; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Lactates; Lactic Acid; Liver; Male; Norepinephrine; Phosphorylases; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
Modulators of the protein kinase C system influence biliary excretion of cationic drugs.
Topics: Alkaloids; Animals; Bile; Biological Transport, Active; Carrier Proteins; Cations; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Liver; Male; Perfusion; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathways.
Topics: Animals; Cells, Cultured; Dinoprostone; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Liver; Male; Pertussis Toxin; Phosphorylases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Insulin-mimetic actions of phorbol ester in cultured adult rat hepatocytes. Lack of phorbol-ester-elicited inhibition of the insulin signal.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Cells, Cultured; Enzyme Activation; Enzyme Induction; Ethers, Cyclic; Fructosediphosphates; Glucagon; Glycolysis; Insulin; Kinetics; Liver; Liver Glycogen; Male; Okadaic Acid; Ornithine Decarboxylase; Phosphoenolpyruvate Carboxykinase (GTP); Phosphofructokinase-2; Phosphoprotein Phosphatases; Phosphotransferases; Protein Kinase C; Pyruvate Kinase; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Glucose-induced insulin secretion from purified beta-cells. A role for modulation of Ca2+ influx by cAMP- and protein kinase C-dependent signal transduction pathways.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Theophylline; Time Factors | 1993 |
Characterization of the effects of adenosine 5'-[beta-thio]-diphosphate in rat liver.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cyclic AMP; Enzyme Activation; Glucagon; In Vitro Techniques; Inosine Triphosphate; Liver; Male; Phosphorylases; Rats; Rats, Wistar; Receptors, Purinergic; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Thionucleotides | 1993 |
Protein kinase C inhibits cyclic adenosine monophosphate generation by histamine and truncated glucagon like peptide 1 in the human gastric cancer cell line HGT-1.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Cyclic AMP; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Histamine; Humans; Peptide Fragments; Pertussis Toxin; Protein Kinase C; Protein Precursors; Receptors, Gastrointestinal Hormone; Receptors, Histamine H2; Staurosporine; Stimulation, Chemical; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells.
Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Glucagon; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Glucagon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Desensitization and phosphorylation of the glucagon-like peptide-1 (GLP-1) receptor by GLP-1 and 4-phorbol 12-myristate 13-acetate.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Indoles; Insulinoma; Molecular Sequence Data; Pancreatic Neoplasms; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Precursors; Rats; Receptors, Glucagon; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Crosstalk between the cAMP and inositol trisphosphate-signalling pathways in pancreatic beta-cells.
Topics: Animals; Caffeine; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Diazoxide; Gallopamil; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Obese; Oscillometry; Potassium; Ryanodine; Signal Transduction; Strontium; Tetradecanoylphorbol Acetate | 1996 |
Regulation of glycosylphosphatidylinositol-specific phospholipase D secretion from beta TC3 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cycloheximide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Immunohistochemistry; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Pancreatic Neoplasms; Peptide Fragments; Phospholipase D; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Characterization of a novel protein kinase C response element in the glucagon gene.
Topics: Animals; Base Sequence; Binding Sites; Calcium; Cell Line; Chromosome Mapping; Cyclic AMP; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme Activation; Glucagon; Hepatocyte Nuclear Factor 3-beta; Islets of Langerhans; Mice; Nuclear Proteins; Oligodeoxyribonucleotides; Protein Kinase C; ras Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1997 |
Co-transfection with protein kinase D confers phorbol-ester-mediated inhibition on glucagon-stimulated cAMP accumulation in COS cells transfected to overexpress glucagon receptors.
Topics: Animals; beta-Adrenergic Receptor Kinases; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; G-Protein-Coupled Receptor Kinase 3; Glucagon; Liver; Male; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Glucagon; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dogs; Enteroendocrine Cells; Enzyme Activation; Enzyme Inhibitors; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Immunohistochemistry; Isoquinolines; Male; Peptide Fragments; Protein Kinase C; Protein Precursors; Somatostatin; Tetradecanoylphorbol Acetate | 1998 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Galanin inhibits glucagon-like peptide-1 secretion through pertussis toxin-sensitive G protein and ATP-dependent potassium channels in rat ileal L-cells.
Topics: Animals; Bombesin; Cells, Cultured; Colforsin; Disopyramide; Dose-Response Relationship, Drug; Galanin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; GTP-Binding Proteins; Ileum; Immunohistochemistry; Male; Microscopy, Fluorescence; Peptide Fragments; Pertussis Toxin; Potassium Channels; Protein Precursors; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Glucose and glucoincretin peptides synergize to induce c-fos, c-jun, junB, zif-268, and nur-77 gene expression in pancreatic beta(INS-1) cells.
Topics: Animals; Cell Line; Cyclic AMP; DNA-Binding Proteins; Drug Synergism; Early Growth Response Protein 1; Gastric Inhibitory Polypeptide; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Immediate-Early Proteins; Islets of Langerhans; Neuropeptides; Nifedipine; Peptide Fragments; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Precursors; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Zinc Fingers | 1998 |
Regulation of glucagon-like peptide-1 synthesis and secretion in the GLUTag enteroendocrine cell line.
Topics: Animals; Carbachol; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enteroendocrine Cells; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Mice; Peptide Fragments; Protein Kinase C; Protein Precursors; Tetradecanoylphorbol Acetate | 1998 |
Evidence for nitric oxide mediated effects on islet hormone secretory phospholipase C signal transduction mechanisms.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cholinergic Agonists; Diazoxide; Enzyme Inhibitors; Female; Glucagon; Hydroxylamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoantigens; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Glucose; Insulinoma; Islets of Langerhans; Kinetics; Membrane Proteins; Pancreatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix.
Topics: Animals; Botulinum Toxins; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Adhesion; Cell Degranulation; Cell Movement; Cell Size; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Diazoxide; Diphosphonates; Enzyme Inhibitors; Extracellular Matrix; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transfection | 2001 |
Role of leptin in the regulation of glucagon-like peptide-1 secretion.
Topics: Animals; Cells, Cultured; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Leptin; Peptide Fragments; Protein Precursors; Rats; Tetradecanoylphorbol Acetate | 2003 |
Decreased glucagon responsiveness by bile acids: a role for protein kinase Calpha and glucagon receptor phosphorylation.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Chenodeoxycholic Acid; Cyclic AMP; Glucagon; Humans; Phosphorylation; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Receptors, G-Protein-Coupled; Receptors, Glucagon; Tetradecanoylphorbol Acetate | 2006 |
Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCalpha and PKCdelta.
Topics: Adult; Aged; Animals; Exocytosis; Glucagon; Glucagon-Secreting Cells; Humans; Mice; Middle Aged; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Transport; Tetradecanoylphorbol Acetate | 2010 |
Protein kinase C-δ signaling regulates glucagon secretion from pancreatic islets.
Topics: Animals; Diabetes Mellitus, Experimental; Disease Progression; Glucagon; Humans; In Vitro Techniques; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase C-delta; Quercetin; Signal Transduction; Tetradecanoylphorbol Acetate | 2017 |