tetradecanoylphorbol acetate has been researched along with genistein in 225 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 175 (77.78) | 18.2507 |
| 2000's | 41 (18.22) | 29.6817 |
| 2010's | 8 (3.56) | 24.3611 |
| 2020's | 1 (0.44) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kimura, G; Koga, Y; Nakamura, K; Nomoto, K; Yoshida, H | 1 |
| Kajiyama, K; Katagiri, K; Katagiri, T; Uehara, Y; Yamamoto, T; Yoshida, T | 1 |
| Jung, G; Lieberknecht, A; Metzger, JW; Offermanns, S; Schmidt, U; Schultz, G; Seifert, R | 1 |
| Akimaru, K; Edashige, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T | 1 |
| Fan, G; Rillema, JA | 1 |
| Richards, JS; Wong, WY | 1 |
| Akimaru, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T; Yoshioka, T | 1 |
| Scott, RE; Wang, H | 1 |
| Humphries, RK; Kay, RJ; Krystal, G; Mui, AL | 1 |
| Aharonovits, O; Granot, Y; Livne, AA; Zik, M | 1 |
| Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Broxmeyer, HE; Hendrie, PC; Kim, YJ; Kwon, BS; Mantel, C; Miyazawa, K; Yang, YC | 1 |
| Carracedo, J; Charron, D; Mooney, N; Ramirez, R | 1 |
| Kaziro, Y; Nakafuku, M; Satoh, T | 1 |
| Dotto, GP; Filvaroff, E; Stern, DF | 1 |
| Clark, EA; Deans, J; Draves, K; Lane, PJ; Ledbetter, JA; McConnell, FM; Schieven, GL | 1 |
| Atluru, D; Atluru, S; Jackson, TM | 1 |
| Bhalla, RC; Chiang, JJ; Loeber, CP; Potts, JD; Runyan, RB; Sharma, RV | 1 |
| Atluru, D; Bjorndahl, JM; Lu, YL; Phillips, CA; Trevillyan, JM | 1 |
| Giasson, E; Haddad, P; Leduc, I; Meloche, S | 1 |
| Huang, TS; Kuo, ML; Lin, JK | 1 |
| Hirai, K; Koike, T; Mizutani, T; Morita, Y; Nozawa, Y | 1 |
| Anel, A; Kleinfeld, AM; Richieri, GV | 1 |
| Hall, A; Ridley, AJ | 1 |
| Anel, A; Boyer, C; Buferne, M; Golstein, P; Schmitt-Verhulst, AM | 1 |
| Herberman, RB; Lin, WC; Rabinowich, H; Whiteside, TL | 1 |
| Walters, JD; Wojcik, MS | 1 |
| Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M | 1 |
| Homma, MK; Krebs, EG; Marumo, F; Nonoguchi, H; Sasaki, S; Terada, Y; Tomita, K; Yamada, T; Yang, T; Yuasa, Y | 1 |
| Bissell, MJ; Desprez, PY; Roskelley, CD | 1 |
| Henrion, D; Laher, I | 1 |
| García-Sáinz, JA; González-Espinosa, C | 1 |
| Bell, LL; Cheung, JY; Lynch, CJ; Miller, BA | 1 |
| Soltoff, SP; Toker, A | 1 |
| de Prost, D; Hakim, J; Khechai, F; Ollivier, V; Ramani, M; Ternisien, C | 1 |
| Cox, AD; Earp, HS; Li, X; Yu, H; Zohn, IE | 1 |
| Hawes, BE; Lefkowitz, RJ; Touhara, K; van Biesen, T | 1 |
| Kung, AW; Lau, KS; Wong, NS | 1 |
| Abel, K; Azad, N; Emanuele, NV; La Paglia, N; Mohagheghpour, N | 1 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A | 2 |
| Kozawa, O; Oiso, Y; Shinoda, J; Suzuki, A; Watanabe, Y | 1 |
| Indelicato, SR; Kirk, G; Kitamura, T; Meyer, L; Miyajima, A; Muir, VC; Parce, JW; Wada, HG | 1 |
| Abraham, RT; Lutz, MP; Miller, LJ; Sutor, SL | 1 |
| Catarsi, S; Drapeau, P | 1 |
| Hoh, E; Kadowaki, T; Kaida, T; Komuro, I; Maemura, K; Nagai, R; Tamemoto, H; Tobe, K; Yamazaki, T; Yazaki, Y | 1 |
| Bongrand, P; Bouhamdan, M; Capo, C; Huang, CK; Mege, JL; Sanguedolce, MV | 1 |
| Joshi-Barve, SS; Rangnekar, VM; Rangnekar, VV; Sells, SF | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Evans, SW; Thompson, D; Whicher, JT | 1 |
| Breu, J; Petryniak, MA; Slack, BE; Srivastava, K; Wurtman, RJ | 1 |
| Chiara, MD; Conde, M; Pintado, E; Sobrino, F | 1 |
| Akisue, T; Inoue, H; Nakamura, S; Shimooku, K | 1 |
| Kozawa, O; Oiso, Y; Suzuki, A | 1 |
| Beery, R; Geier, A; Haimsohn, M; Hemi, R; Karasik, A; Malik, Z; Weiss, C | 1 |
| Kang, LY; Yang, YC | 1 |
| Damen, JE; Humphries, RK; Krosl, J; Krystal, G | 1 |
| Fujita, S; Horiuchi, T; Watanabe, I | 1 |
| Briscoe, CP; Cross, M; Martin, A; Wakelam, MJ | 1 |
| Barnes, MJ; Farndale, RW; Hargreaves, PG; Licking, EF; Sage, SO; Sargeant, P | 1 |
| Barnes, S; Bowen, R; Cai, Q; Wang, Y; Wei, H | 1 |
| Niitani, H; Nishio, K; Saijo, N; Takeda, Y | 1 |
| Fusamoto, H; Hayashi, N; Horimoto, M; Ito, T; Kamada, T; Kaneko, A; Kasahara, A; Sasaki, Y; Tanaka, Y | 1 |
| Kim, HS; Lee, YH; Pai, JK; Ryu, SH; Suh, PG | 1 |
| Parks, WC; Pentland, AP; Sudbeck, BD; Welgus, HG | 1 |
| Joggerst, B; Parton, RG; Simons, K | 1 |
| Almazan, G; Radhakrishna, M | 1 |
| Asaoka, Y; Nishizuka, Y; Tsujishita, Y | 1 |
| Butler, AP; Fischer, SM; Lee, WY; Locniskar, MF | 1 |
| Welsh, N | 1 |
| Borrego, F; Lopez-Beltran, A; Peña, J; Solana, R | 1 |
| Berton, G; Laudanna, C; Rossi, F | 1 |
| Broxterman, HJ; Eekman, CA; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ; Versantvoort, CH | 1 |
| Hale, P; Miller, CC; Pentland, AP | 1 |
| Graham, A; Russell, LJ | 1 |
| Azuma, EK; Kitagawa, S; Mizoguchi, H; Saito, M; Takaku, F; Umezawa, K; Yuo, A | 1 |
| Combadière, C; el Benna, J; Hakim, J; Pedruzzi, E; Périanin, A | 1 |
| Martin, J; Meenakshi, T; Ross, FP; Teitelbaum, SL | 1 |
| Endo, Y; Furuya, S; Ito, T; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Akiba, S; Fujii, T; Sato, T | 1 |
| Huang, XY; Morielli, AD; Peralta, EG | 1 |
| Mayer, AM; Spitzer, JA | 1 |
| Ahmed, A; Ferriani, RA; Fountain, SA; Plevin, R; Shoaibi, MA; Smith, SK | 1 |
| Iwashita, M; Matsuzaki, N; Neki, R; Okada, T; Saji, F; Shimoya, K; Tanizawa, O; Yamanaka, K | 1 |
| McCabe, MJ; Orrenius, S | 1 |
| Barnes, S; Bowen, R; Frenkel, K; Wei, H; Wei, L | 1 |
| Hurme, M; Matikainen, S; Palkama, T | 1 |
| Borrego, F; Peña, J; Solana, R | 1 |
| Antonipillai, I | 1 |
| Burns, DM; Kawase, T; Ogata, S; Orikasa, M | 1 |
| Herwig, S; Ma, Y; Su, Q; Tempst, P; Zhang, W | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Kloss, H; Tollkühn, B; Verspohl, EJ | 1 |
| Ahmed, A; Ferriani, RA; Smith, SK | 1 |
| Adachi, T; Nakamura, T; Nakashima, S; Nozawa, Y; Saji, S | 1 |
| Koga, Y; Kubo, C; Nomoto, K; Okumura, Y; Sudo, N; Tanaka, K | 1 |
| Borda, ES; Sterin-Borda, L; Wald, MR | 1 |
| Fuhrer, DK; Hamilton, J; Steussy, CN; Yang, L; Yang, YC | 1 |
| Tseng, CP; Verma, AK | 1 |
| Chen, HL; Gu, JX; Ju, TZ; Qin, H | 1 |
| Agrawal, DK; Ali, N | 1 |
| Bréant, B; Karlsson, T; Lavergne, C; Mares, J; Welsh, M | 1 |
| Auberger, P; Baeuerle, PA; Farahifar, D; Imbert, V; Livolsi, A; Mueller-Dieckmann, C; Pahl, HL; Peyron, JF; Rossi, B; Rupec, RA; Traenckner, EB | 1 |
| Columbo, M; Horowitz, EM; Kagey-Sobotka, A; Lichtenstein, LM | 1 |
| Buckley, AR; Buckley, DJ; Rao, YP | 1 |
| Abreu, C; Hurley, MM; Kessler, M; Marcello, K | 1 |
| Farndale, RW; Hargreaves, PG; Jenner, S; Merritt, JE; Sage, SO | 1 |
| Petersen, MM; Steadman, R; Williams, JD | 1 |
| Shaw, MK | 1 |
| Chik, CL; Ho, AK; Ogiwara, T | 1 |
| Aikawa, R; Hiroi, Y; Komuro, I; Kudoh, S; Mizuno, T; Shiojima, I; Yamazaki, T; Yazaki, Y; Zou, Y | 1 |
| Leffler, CW; Parfenova, H; Rama, GP | 1 |
| Asaka, M; Iwasaki, H; Kato, K; Kawamura, K; Kobayashi, M; Miyazaki, T; Musashi, M; Sakurada, K; Sasaki, M; Sudo, T; Tanaka, E; Tsuda, Y | 1 |
| Carson, DD; Ding, ZM; Kuo, MT; Wegner, CC; Zhou, X | 1 |
| Benahmed, M; Kolodié, L; Le Magueresse-Battistoni, B; Morera, AM; Pernod, G | 1 |
| Csaba, G; Kovács, P; Nakashima, S; Nozawa, Y | 1 |
| Driessens, MH; Roos, E; Soede, RD; van Hulten, PE; van Rijthoven, EA | 1 |
| Billings, RE; Collier, JM; Miller, DR | 1 |
| Heiman, AS; Tonner, LE | 1 |
| al-Hassani, M; Natarajan, V; Scribner, WM; Vepa, S | 1 |
| Czuprynski, CJ; Yu, PW | 1 |
| Boveris, A; Carreras, MC; Pargament, GA; Poderoso, JJ; Riobó, NA | 1 |
| Aguirre Ghiso, JA; Alonso, DF; Arregui, C; Bal de Kier Joffé, E; Farías, EF | 1 |
| Ito, Y; Nakashima, S; Nozawa, Y | 1 |
| Bragado, MJ; Groblewski, GE; Williams, JA | 1 |
| Benehacene, A; Kamps, M; Scheele, JS; White, FC | 1 |
| Chung, CH; Kang, MS; Kwon, H; Park, JY; Shin, KS | 1 |
| Goppelt-Struebe, M; Stroebel, M | 1 |
| Jorcano, JL; Paramio, JM | 1 |
| Bartlett, ST; Kuo, PC; Schroeder, RA | 1 |
| Barsig, J; Nüsing, RM | 1 |
| Baylink, DJ; Mohan, S; Sampath, K; Srinivasan, N | 1 |
| Haase, G; Holland, R; Lütticken, R; Podbielski, A; Schnitzler, N; Schweizer, K; Spellerberg, B | 1 |
| García-Sáinz, JA; Medina, LC; Vázquez-Prado, J | 1 |
| Alper, SL; Izumo, S; Lee, IW; Malek, AM | 1 |
| Abts, H; Diehl, V; Kube, D; Tesch, H; Von Knethen, A | 1 |
| Cho, CH; Ding, SZ; Lam, SK | 1 |
| Schläpfer, I; Schmid, C; Veldman, CM | 1 |
| Fukuzawa, K; Houchi, H; Oka, M; Okuno, M; Tokumura, A; Tsuchiya, K | 1 |
| Gylfe, E; Liu, YJ | 1 |
| Kuan, CY; Lee, SC; Wen, ZD; Yang, SD | 1 |
| Evans, DL; Jaso-Friedmann, L; Leary, JH | 1 |
| Chik, CL; Ho, AK; Negishi, T | 1 |
| Baines, CP; Cohen, MV; Downey, JM; Wang, L | 1 |
| Aggarwal, BB; Chaturvedi, MM; Manna, SK; Natarajan, K | 1 |
| Dugué, B; Ekokoski, E; Törnquist, K | 1 |
| Hasebe, A; Sasaki, T; Shibata, K; Watanabe, T | 1 |
| Linder, S; Ljungdahl, S; Shoshan, MC; Swedenborg, J; Zhou, JN | 1 |
| Bennett, JS; Loh, E; Qi, W; Vilaire, G | 1 |
| de Boland, AR; Norman, AW | 1 |
| Kodama, H; Kurashige, T; Masuoka, N; Ohta, J; Sagara, Y; Shimazaki, Y; Ubuka, T; Wakiguchi, H; Zhang, J | 1 |
| Fyhrquist, F; Nyman, T; Pacek, P; Saijonmaa, O | 1 |
| Alanko, T; Bhowmik, A; Joutsi, T; Kivilaakso, E; Paavonen, T; Paimela, H; Saksela, O | 1 |
| Ma, TY; McCloud, E; Ortiz, A; Said, HM | 1 |
| Hakki, ZW; Kim-Park, WK; Kowolik, MJ; Moore, MA | 1 |
| Asano, M; Fujita, R; Hong, Y; Kawakami, Y; Matsuo, K; Miyauchi, T; Mizutani, M; Nakajima, T; Okuda, Y; Soma, M; Sone, H; Suzuki, H; Suzuki, S; Tsurumaru, K; Yamashita, K | 1 |
| Mergler, S; Steinhausen, K; Strauss, O; Wiederholt, M | 1 |
| Garcia, LJ; Jensen, RT; Rosado, JA; Salido, GM | 1 |
| Bowen, R; Lebwohl, M; Wei, H; Zhang, X | 1 |
| Hagiwara, Y; Hanada, M; Kambe, T; Kubo, T; Saito, E | 1 |
| Bradford, MD; Soltoff, SP | 1 |
| Arts, J; Grimbergen, J; Kooistra, T; Toet, K | 1 |
| Burns, CJ; Harris, TE; Jones, PM; Persaud, SJ | 1 |
| Kodama, H; Sagara, Y; Spirito, A; Sugahara, K; Zhang, J; Zhang, M | 1 |
| Kansra, SV; Reddy, MA; Shukla, SD; Weng, YI | 1 |
| Browning, MD; Dudek, E; Lei, S; Lu, WY; MacDonald, JF; Orser, BA; Xiong, ZG | 1 |
| Banerjee, A; Harken, AH; McIntyre, RC; Meldrum, DR; Meng, X; Pulido, EJ; Selzman, CH; Shames, BD | 1 |
| Piper, HM; Schäfer, M; Schlüter, KD; Simm, A; Taimor, G | 1 |
| Kodama, H; Seto, K; Sugahara, K; Ushikoshi, I; Ushikoshi, S; Zhang, J | 1 |
| Gómez-Muñoz, A; Hundal, R; O'Brien, L; Steinbrecher, UP | 1 |
| Berg, RW; Krissansen, GW; Leung, E; Yang, Y; Zhang, WV | 1 |
| Floyd-Smith, G; Yu, F | 1 |
| Bailey, JL; Fortier, MA; Guilbault, LA; Legault, S; Rouillier, P | 1 |
| de Araujo, EG; dos Santos, AA | 1 |
| Doerr, G; Fleck, E; Graf, K; Kappert, K; Schmidt, G; Wollert-Wulf, B | 1 |
| Cafferata, EG; Giordano, L; González-Guerrico, AM; Pivetta, OH; Santa-Coloma, TA | 1 |
| Argenzio, RA; Blikslager, AT; Rhoads, JM; Roberts, MC; Young, KM | 1 |
| Ha-Lee, YM; Kim, YK; Lee, Y; Sohn, J | 1 |
| Creuzet, C; Dupouy-Camet, J; Robert-Gangneux, F; Roisin, MP | 1 |
| Kudoh, A; Matsuki, A | 1 |
| Ikewaki, N; Inoko, H; Inoue, H; Mori, N; Tamauchi, H; Yamada, A; Yamao, H | 1 |
| Chen, CC; Chen, JJ; Chiu, KT; Sun, YT | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Kuzuya, T; Mori, H; Node, K; Sakata, Y; Sanada, S; Shinozaki, Y; Takashima, S | 1 |
| Davis, HW; Zhao, Y | 1 |
| Bosmann, M; Chang, JH; Hellmuth, M; Huwiler, A; Mühl, H; Ninic, R; Nold, M; Paulukat, J; Pfeilschifter, J | 1 |
| Cheng, S; Mao, J; Rehder, V | 1 |
| Herrera, R; Petruzzelli, L; Takami, M | 1 |
| Kimmich, GA; Manglapus, M; Randles, J; Roussie, J | 1 |
| Han, C; Lei, B; Zhang, Y | 1 |
| Barnes, S; Boersma, BJ; Darley-Usmar, VM; Kim, H; Kirk, M; Patel, R; Smith, M; Wang, CC; Xu, J | 1 |
| Låg, M; Refsnes, M; Schwarze, PE; Thoresen, GH; Thrane, EV | 1 |
| Ma, J; Zhou, X | 1 |
| He, S; Li, X; Zhao, M | 1 |
| Tou, JS | 1 |
| Balduzzi, R; Cupello, A; Robello, M | 1 |
| Fladeby, C; Grønning, M; Serck-Hanssen, G; Skar, R | 1 |
| Ciereszko, RE; Dusza, L; Kaminska, B; Opalka, M | 1 |
| Chen, G; Kodama, H; Lu, H; Manabe, M; Wang, C; Yamashita, K | 1 |
| Balabanova, L; Fedinec, AL; Leffler, CW; Parfenova, H; Sullivan, CD; Wang, X | 1 |
| Mei, YA; Sun, JT; Wei, H; Zhang, ZH; Zhou, HQ | 1 |
| Namiki, H; Suzuki, K; Takahashi, H | 1 |
| Chain, BM; Cho, JY; Katz, DR | 1 |
| Chen, CT; Gillespie, GY; Goldman, CK; Hong, TM; Teng, LJ; Tsai, JC | 1 |
| Cho, JY; Chun, T; Hong, S; Jung, JH; Kim, AR; Kim, SH; Rhee, MH; Yoo, ES | 1 |
| Klink, M; Sulowska, Z; Tchorzewski, H | 1 |
| Bird, PS; Seymour, GJ; Sosroseno, W | 1 |
| Kim, CH; Kim, HM; Park, SY; Park, WH | 1 |
| Doi, SQ; Glerum, S; Mendonça, MC; Sellitti, DF | 1 |
| Lau, TY; Leung, LK | 1 |
| Choi, HS; Kim, BY; Kim, JW; Kim, KH; Lee, HG; Park, OJ; Park, SN; Shim, JH; Shin, JI; Yoon, DY | 1 |
| Müller, C; Steege, A; Steinberg, P; Thierbach, R; Toyokuni, S; Ullmann, K; Wiencierz, AM | 1 |
| Adolfo García-Sáinz, J; Alcántara-Hernández, R | 1 |
| Hwang, JT; Lee, YK; Park, OJ; Shin, JI | 1 |
| Arai, T; Hamashima, Y; Hasegawa, J; Kajimoto, T; Node, M; Suzuki, N; Tanaka, R; Tokuda, H; Tsujii, H; Yamada, T | 1 |
| Ali, F; Khan, AQ; Khan, R; Lateef, A; Rehman, MU; Sultana, S; Tahir, M | 1 |
| Baracat, MM; Casagrande, R; Fonseca, MJ; Georgetti, SR; Verri, WA; Vicentini, FT | 1 |
| Chen, BC; Kao, ST; Liu, CJ; Wang, SD; Yeh, CC | 1 |
| Chung, MH; Haegeman, G; Kim, DH; Kim, HN; Kim, JH; Na, HK; Surh, YJ | 1 |
| Jung, WS; Kim, DH; Kim, ME; Lee, HN; Lee, HW; Lee, JS; Seon, JK; Youn, HY | 1 |
| Mukherjee, S; Sengupta Bandyopadhyay, S | 1 |
| Araújo, JMD; Camargo, EA; Corrêa, CB; de Souza, EV; Felix, FB; Grespan, R; Pinho, V | 1 |
1 review(s) available for tetradecanoylphorbol acetate and genistein
| Article | Year |
|---|---|
Receptor associated phosphorylation following monoclonal antibody or synthetic peptide binding to nonspecific cytotoxic cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antibodies, Monoclonal; Cytotoxicity, Immunologic; Genistein; Ictaluridae; Isoquinolines; Killer Cells, Natural; Molecular Sequence Data; Oxazolone; Peptides; Phosphorylation; Phosphoserine; Protein Kinase C; Quinolines; Serine; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
224 other study(ies) available for tetradecanoylphorbol acetate and genistein
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
A lymphocyte-specific protein tyrosine kinase, p56lck, regulates the PMA-induced internalization of CD4.
Topics: Blotting, Western; CD4 Antigens; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Expression; Genistein; Humans; Isoflavones; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Protein-Tyrosine Kinases; RNA; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Modulation of monocytic differentiation of HL-60 cells by inhibitors of protein tyrosine kinases.
Topics: Antibiotics, Antineoplastic; Antibody-Dependent Cell Cytotoxicity; Benzoquinones; Cell Differentiation; Cholecalciferol; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Monocytes; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells.
Topics: Blotting, Western; Bucladesine; Cell Differentiation; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Lipoproteins; Neutrophils; Pertussis Toxin; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1992 |
Modulation of TNF-alpha-priming and stimulation-dependent superoxide generation in human neutrophils by protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cinnamates; Diglycerides; Genistein; Guinea Pigs; Humans; Isoflavones; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Staurosporine; Sulfides; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Effect of a tyrosine kinase inhibitor, genistein, on the actions of prolactin in cultured mouse mammary tissues.
Topics: Animals; Caseins; Cells, Cultured; Cyclic AMP; Enzyme Activation; Female; Genistein; Isoflavones; Lactose; Lipids; Mammary Glands, Animal; Mice; Ornithine Decarboxylase; Pregnancy; Prolactin; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Induction of prostaglandin H synthase in rat preovulatory follicles by gonadotropin-releasing hormone.
Topics: Animals; Cells, Cultured; Cyclic AMP; Dinoprost; Enzyme Induction; Epidermal Growth Factor; Estrogens, Non-Steroidal; Female; Genistein; Gonadotropin-Releasing Hormone; Isoflavones; Kinetics; Luteinizing Hormone; Ovarian Follicle; Progesterone; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Sexual Maturation; Tetradecanoylphorbol Acetate | 1992 |
Effect of tumor necrosis factor-alpha on the stimulus-coupled responses of neutrophils and their modulation by various inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Calcium; Dose-Response Relationship, Drug; Genistein; Humans; In Vitro Techniques; Isoflavones; Isoquinolines; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Induction of c-jun independent of PKC, pertussis toxin-sensitive G protein, and polyamines in quiescent SV40-transformed 3T3 T cells.
Topics: 3T3 Cells; Alkaloids; Animals; Antigens, Polyomavirus Transforming; Cell Division; Cell Line, Transformed; Eflornithine; Gene Expression; Genes, jun; Genistein; GTP-Binding Proteins; Insulin; Isoflavones; Kinetics; Mice; Pertussis Toxin; Polyamines; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Putrescine; Signal Transduction; Simian virus 40; Spermidine; Staurosporine; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella | 1992 |
Ligand-induced phosphorylation of the murine interleukin 3 receptor signals its cleavage.
Topics: Alkaloids; Animals; Blotting, Western; Cell Line; Chloroquine; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Interleukin-5; Isoflavones; Kinetics; Ligands; Macromolecular Substances; Mice; Molecular Weight; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Interleukin-3; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Vasopressin elevation of Na+/H+ exchange is inhibited by genistein in human blood platelets.
Topics: Adult; Alkaloids; Arginine Vasopressin; Blood Platelets; Carrier Proteins; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Middle Aged; Phosphorylation; Protein Kinase C; Protons; Sodium; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida | 1992 |
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Recombinant human interleukin-9 induces protein tyrosine phosphorylation and synergizes with steel factor to stimulate proliferation of the human factor-dependent cell line, M07e.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Genistein; Hematopoietic Cell Growth Factors; Humans; Immunoblotting; Interleukin-9; Isoflavones; Kinetics; Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
HLA class-II-mediated homotypic aggregation: involvement of a protein tyrosine kinase and protein kinase C.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Calcium; Cell Aggregation; Cell Line; Cytoskeleton; Enzyme Activation; Flow Cytometry; Genistein; HLA-D Antigens; Humans; Isoflavones; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Cooperation; Magnesium; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Differentiation factors, including nerve growth factor, fibroblast growth factor, and interleukin-6, induce an accumulation of an active Ras.GTP complex in rat pheochromocytoma PC12 cells.
Topics: Animals; Cell Differentiation; Fibroblast Growth Factors; Genistein; Guanosine Triphosphate; In Vitro Techniques; Interleukin-6; Isoflavones; Nerve Growth Factors; PC12 Cells; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Vanadates | 1992 |
Tyrosine phosphorylation is an early and specific event involved in primary keratinocyte differentiation.
Topics: Animals; Blotting, Western; Calcium; Cell Differentiation; Cytoskeleton; Cytosol; Genistein; Isoflavones; Keratinocytes; Mice; Mice, Inbred Strains; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transglutaminases; Tyrosine | 1990 |
The role of tyrosine phosphorylation in signal transduction through surface Ig in human B cells. Inhibition of tyrosine phosphorylation prevents intracellular calcium release.
Topics: Aluminum; Aluminum Compounds; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Benzoquinones; Calcium; CD40 Antigens; Cell Line; Cross-Linking Reagents; Fluorides; Genistein; Humans; Immunoglobulin M; Isoflavones; Lactams, Macrocyclic; Models, Biological; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Receptors, Antigen, B-Cell; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1991 |
Genistein, a selective protein tyrosine kinase inhibitor, inhibits interleukin-2 and leukotriene B4 production from human mononuclear cells.
Topics: Calcimycin; Cells, Cultured; Genistein; Humans; Interleukin-2; Isoflavones; Leukocytes, Mononuclear; Leukotriene B4; Lymphocyte Activation; Phytohemagglutinins; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate | 1991 |
Signal transduction of a tissue interaction during embryonic heart development.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Chick Embryo; Cholera Toxin; Endothelium; Enzyme Activation; Extracellular Matrix Proteins; Fetal Heart; Genistein; GTP-Binding Proteins; Isoflavones; Isoquinolines; Myocardium; Pertussis Toxin; Phenotype; Piperazines; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD3 Complex; Genistein; Humans; Interleukin-2; Isoflavones; Lectins, C-Type; Lymphocyte Activation; Phosphatidylinositols; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, fos; Genistein; Isoflavones; Lactams, Macrocyclic; Male; Muscle Proteins; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Inbred BN; Receptors, Angiotensin; Rifabutin; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcriptional Activation; Type C Phospholipases; Tyrosine | 1995 |
Preferential requirement for protein tyrosine phosphatase activity in the 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human colon cancer cells.
Topics: Cell Differentiation; Chlorides; Colonic Neoplasms; Enzyme Activation; Ethers, Cyclic; Genistein; Humans; Isoflavones; Okadaic Acid; Protein Tyrosine Phosphatases; Proteoglycans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc Compounds | 1995 |
SCF/c-kit receptor-mediated arachidonic acid liberation in rat mast cells. Involvement of PLD activation associated tyrosine phosphorylation.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Diglycerides; Genistein; Hematopoietic Cell Growth Factors; Isoflavones; Kinetics; Mast Cells; Myristic Acid; Myristic Acids; Phosphatidylcholines; Propranolol; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Stem Cell Factor; Tetradecanoylphorbol Acetate; Vanadates | 1993 |
A tyrosine phosphorylation requirement for cytotoxic T lymphocyte degranulation.
Topics: Animals; Arsenicals; Calcium; Clone Cells; Concanavalin A; Fatty Acids, Nonesterified; Genistein; Ionomycin; Isoflavones; Kinetics; Lymphocyte Activation; Mice; Molecular Weight; Oleic Acid; Oleic Acids; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Isoflavones; Lysophospholipids; Mice; Models, Biological; Myosins; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1994 |
T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A.
Topics: Animals; Antigens, Surface; Benzoquinones; CD3 Complex; Cell Survival; Clone Cells; Cyclosporine; fas Receptor; Gene Expression; Genistein; In Vitro Techniques; Ionomycin; Isoflavones; Lactams, Macrocyclic; Mice; Protein-Tyrosine Kinases; Quinones; Receptors, Antigen, T-Cell; Rifabutin; RNA, Messenger; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1994 |
Signaling via CD7 molecules on human NK cells. Induction of tyrosine phosphorylation and beta 1 integrin-mediated adhesion to fibronectin.
Topics: Alkaloids; Amino Acid Sequence; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Adhesion; Cytochalasin B; Enzyme Activation; Fibronectins; Genistein; Humans; In Vitro Techniques; Integrins; Isoflavones; Killer Cells, Natural; Molecular Sequence Data; Peptides; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Fibronectin; Receptors, IgG; Receptors, Immunologic; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Polyamine transport in human promyelocytic leukemia cells and polymorphonuclear leukocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Biological Transport; Cell Line; Genistein; Gramicidin; Humans; In Vitro Techniques; Ionomycin; Isoflavones; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Piperazines; Protein Kinase Inhibitors; Putrescine; Spermidine; Spermine; Sulfonamides; Temperature; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin | 1994 |
Sequential activation of Raf-1 kinase, mitogen-activated protein (MAP) kinase kinase, MAP kinase, and S6 kinase by hyperosmolality in renal cells.
Topics: Amino Acid Sequence; Animals; Benzoquinones; Cells, Cultured; Dogs; Enzyme Activation; Genistein; Inositol 1,4,5-Trisphosphate; Isoflavones; Kidney Medulla; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Naphthalenes; Osmolar Concentration; Phosphorylation; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinones; Ribosomal Protein S6 Kinases; Rifabutin; Tetradecanoylphorbol Acetate | 1994 |
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction.
Topics: Animals; Caseins; Cell Aggregation; Cells, Cultured; Extracellular Matrix; Female; Gene Expression Regulation, Developmental; Genistein; In Vitro Techniques; Integrins; Isoflavones; Mice; Phosphotyrosine; Prolactin; Receptor Aggregation; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1994 |
Insulin potentiates norepinephrine-induced vascular tone by activation of protein kinase C and tyrosine kinase.
Topics: Animals; Calcium; Drug Synergism; Genistein; Histamine; In Vitro Techniques; Insulin; Isoflavones; Male; Naphthalenes; Norepinephrine; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1994 |
Protein kinases and phosphatases modulate c-fos expression in rat hepatocytes. Effects of angiotensin II and phorbol myristate acetate.
Topics: Alkaloids; Angiotensin II; Animals; Ethers, Cyclic; Female; Gene Expression; Genes, fos; Genistein; Isoflavones; Marine Toxins; Microcystins; Naphthalenes; Okadaic Acid; Oxazoles; Peptides, Cyclic; Phosphoprotein Phosphatases; Phosphorylation; Polycyclic Compounds; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.
Topics: Adult; Alkaloids; Analog-Digital Conversion; Biological Transport; Bucladesine; Calcium; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Erythroid Precursor Cells; Erythropoietin; Genistein; Humans; Image Processing, Computer-Assisted; Indoles; Intercellular Signaling Peptides and Proteins; Intracellular Fluid; Isoflavones; Isoquinolines; Naphthalenes; Peptides; Phosphorylation; Polycyclic Compounds; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Pyrroles; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Videotape Recording; Wasp Venoms | 1994 |
Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells.
Topics: Alkaloids; Animals; Biological Transport; Carbachol; Cell Membrane; Cells, Cultured; Enzyme Activation; Epithelial Cells; Epithelium; ErbB Receptors; Genistein; Isoenzymes; Isoflavones; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Receptor, Insulin; Salivary Glands; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Protein tyrosine kinase activation is required for LPS and PMA induction of tissue factor mRNA in human blood monocytes.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Benzoquinones; Enzyme Activation; Gene Expression Regulation; Genistein; Humans; Isoflavones; Lactams, Macrocyclic; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Lipopolysaccharides; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription, Genetic | 1995 |
Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epithelium; Genistein; Isoflavones; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1995 |
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Androstadienes; Animals; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chlorocebus aethiops; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Kidney; Kinetics; Lactams, Macrocyclic; Macromolecular Substances; Pertussis Toxin; Phosphates; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); Quinones; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Rifabutin; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella; Wortmannin | 1995 |
Interferon-gamma increases intracellular calcium and inositol phosphates in primary human thyroid cell culture.
Topics: Alkaloids; Calcium; Cell Line; Culture Media; Egtazic Acid; Enzyme Inhibitors; Genistein; Humans; Inositol Phosphates; Interferon-gamma; Isoflavones; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1995 |
Signal requirements for production of luteinizing hormone releasing-hormone by human T cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Aged; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Genistein; Gonadotropin-Releasing Hormone; Humans; Interleukin-2; Isoflavones; Isoquinolines; Lectins, C-Type; Male; Middle Aged; Phytohemagglutinins; Piperazines; Protein Kinase C; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1995 |
Genistein inhibits potentiation by wortmannin of protein kinase C-activated phospholipase D in osteoblast-like cells.
Topics: 3T3 Cells; Androstadienes; Animals; Choline; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Genistein; Isoflavones; Kinetics; Mice; Osteoblasts; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Wortmannin | 1995 |
Effect of platelet-derived growth factor on phosphatidylcholine-hydrolyzing phospholipase D in osteoblast-like cells.
Topics: Animals; Calcium; Cells, Cultured; Choline; Cinnamates; DNA; Enzyme Activation; Genistein; Inositol Phosphates; Isoflavones; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Tetradecanoylphorbol Acetate | 1995 |
GM-CSF triggers a rapid, glucose dependent extracellular acidification by TF-1 cells: evidence for sodium/proton antiporter and PKC mediated activation of acid production.
Topics: Benzoquinones; Bone Marrow; Bone Marrow Cells; Carrier Proteins; Cell Division; Cell Line; Ethers, Cyclic; Genistein; Glucose; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen-Ion Concentration; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Polycyclic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1993 |
A role for cholecystokinin-stimulated protein tyrosine phosphorylation in regulated secretion by the pancreatic acinar cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Cells, Cultured; Cholecystokinin; Genistein; Isoflavones; Isoquinolines; Kinetics; Male; Pancreas; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Tyrosine kinase-dependent selection of transmitter responses induced by neuronal contact.
Topics: Animals; Cations; Cell Communication; Cells, Cultured; Genistein; Ion Channels; Isoflavones; Leeches; Microelectrodes; Neurons; Neurotransmitter Agents; Phenols; Protein Kinase C; Protein-Tyrosine Kinases; Synapses; Tetradecanoylphorbol Acetate | 1993 |
Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes.
Topics: Alkaloids; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gene Expression; Genes, fos; Genistein; Isoflavones; Kinetics; Myelin Basic Protein; Myocardium; Nitriles; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tyrphostins | 1993 |
Zymosan-induced tyrosine phosphorylations in human monocytes. Role of protein kinase C.
Topics: Catechols; Genistein; Humans; In Vitro Techniques; Isoflavones; Molecular Weight; Monocytes; Naphthalenes; Nitriles; Phosphoproteins; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Tyrosine; Tyrphostins; Vanadium; Zymosan | 1993 |
Interleukin-1-inducible expression of gro-beta via NF-kappa B activation is dependent upon tyrosine kinase signaling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Colforsin; Cytomegalovirus; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, jun; Genes, myc; Genistein; Growth Substances; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1; Isoflavones; L Cells; Melanoma; Mice; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
Interleukin 6 signal transduction in a human hepatoma cell line (Hep G2).
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute-Phase Proteins; Alkaloids; Carcinoma, Hepatocellular; Genistein; Humans; Interleukin-1; Interleukin-6; Isoflavones; Isoquinolines; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Topics: Alkaloids; Amyloid; Carbachol; Cell Line; Genistein; Humans; Isoflavones; Phosphorylation; Prion Proteins; Prions; Protein Kinase Inhibitors; Protein Precursors; Protein Tyrosine Phosphatases; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Modulation of phorbol ester-induced respiratory burst by vanadate, genistein, and phenylarsine oxide in mouse macrophages.
Topics: Animals; Arsenicals; Genistein; Isoflavones; Macrophages, Peritoneal; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Potential role of protein phosphorylation in GTP-gamma-S-dependent activation of phospholipase D.
Topics: Adenosine Triphosphate; Alkaloids; Cell Line; Enzyme Activation; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoflavones; Phospholipase D; Phosphorylation; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Tyrosine kinase regulates phospholipase D activation at a point downstream from protein kinase C in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Animals, Newborn; Catechols; Choline; Clone Cells; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Isoflavones; Kinetics; Mice; Nitriles; Osteoblasts; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Skull; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1995 |
Multiple pathways are involved in protection of MCF-7 cells against death due to protein synthesis inhibition.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aurintricarboxylic Acid; Breast Neoplasms; Cell Survival; Cycloheximide; DNA Damage; Genistein; Humans; Insulin-Like Growth Factor I; Isoflavones; Microscopy, Electron; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Activation of junB and c-myc primary response genes by interleukin 9 in a human factor-dependent cell line.
Topics: Benzoquinones; Gene Expression Regulation; Genes, jun; Genes, myc; Genistein; Growth Substances; Humans; Interleukin-9; Isoflavones; Lactams, Macrocyclic; Protein Kinase C; Protein Kinase Inhibitors; Quinones; Recombinant Proteins; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA-Binding Proteins; Erythroid-Specific DNA-Binding Factors; Erythropoietin; Gene Transfer Techniques; Genistein; Globins; Interleukin-3; Isoflavones; Kinetics; Protein Kinase C; Receptors, Erythropoietin; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
Role of protein kinase C activation in synthesis of complement components C2 and factor B in interferon-gamma-stimulated human fibroblasts, glioblastoma cell line A172 and monocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Benzoquinones; Calcium; Cells, Cultured; Complement C2; Complement Factor B; Enzyme Activation; Fibroblasts; Genistein; Glioblastoma; Humans; Interferon gamma Receptor; Interferon-gamma; Isoflavones; Isoquinolines; Lactams, Macrocyclic; Monocytes; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Receptors, Interferon; Rifabutin; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Up-Regulation | 1995 |
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Genistein; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Isoflavones; Kinetics; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
The tyrosine kinase inhibitors, genistein and methyl 2,5-dihydroxycinnamate, inhibit the release of (3H)arachidonate from human platelets stimulated by thrombin or collagen.
Topics: Adenosine Triphosphate; Apyrase; Arachidonic Acid; Blood Platelets; Calcium; Cinnamates; Collagen; Enzyme Activation; Genistein; Humans; Indomethacin; Isoflavones; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin | 1994 |
Antioxidant and antipromotional effects of the soybean isoflavone genistein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Cell Differentiation; Female; Flavonoids; Gene Expression; Genistein; Glycine max; Humans; Hydrogen Peroxide; Intestine, Small; Isoflavones; Mice; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthine Oxidase | 1995 |
Reversal of multidrug resistance by tyrosine-kinase inhibitors in a non-P-glycoprotein-mediated multidrug-resistant cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Carrier Proteins; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Genistein; Humans; Isoflavones; Membrane Glycoproteins; Molecular Sequence Data; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Characterization of signaling pathways to Na+/H+ exchanger activation with epidermal growth factor in hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Cells, Cultured; Epidermal Growth Factor; Genistein; Hydrogen-Ion Concentration; Isoflavones; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Activation of phospholipase D induced by platelet-derived growth factor is dependent upon the level of phospholipase C-gamma 1.
Topics: 3T3 Cells; Alkaloids; Animals; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Genistein; Glycerophospholipids; Inositol Phosphates; Isoenzymes; Isoflavones; Mice; Phosphatidic Acids; Phospholipase C gamma; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Collagen-stimulated induction of keratinocyte collagenase is mediated via tyrosine kinase and protein kinase C activities.
Topics: Alkaloids; Cells, Cultured; Collagen; Collagenases; Enzyme Induction; Genes, fos; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Keratinocytes; Prostaglandins; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Regulated internalization of caveolae.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Biological Transport; Caveolin 1; Caveolins; Cell Line; Cell Membrane; Cytochalasin D; Ethers, Cyclic; Genistein; Hypertonic Solutions; Isoflavones; Membrane Proteins; Microscopy, Electron; Microtubules; Nocodazole; Okadaic Acid; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Protein kinases mediate basic fibroblast growth factor's stimulation of proliferation and c-fos induction in oligodendrocyte progenitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Biomarkers; Brain; Brain Stem; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Gene Expression; Genes, fos; Genistein; Immunohistochemistry; Isoflavones; Isoquinolines; Kinetics; Oligodendroglia; Piperazines; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 1994 |
Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Electroporation; Fatty Acids, Nonesterified; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Homeostasis; Humans; Hydrogen-Ion Concentration; Isoflavones; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured; Vanadates | 1994 |
Signal transduction pathway(s) involved in phorbol ester and autocrine induction of interleukin-1 alpha mRNA in murine keratinocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Enzyme Activation; Gene Expression Regulation; Genistein; Interleukin-1; Isoflavones; Isoquinolines; Keratinocytes; Mice; Mitogen-Activated Protein Kinase 1; NF-kappa B; Piperazines; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
A role for tyrosine kinase activation in interleukin-1 beta induced nitric oxide production in the insulin producing cell line RINm-5F.
Topics: Alkaloids; Animals; Catechols; Cell Line; Cyclosporine; Enzyme Activation; Genistein; Insulin; Interleukin-1; Isoflavones; Nitric Oxide; Nitriles; Protein-Tyrosine Kinases; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tyrphostins | 1994 |
Downregulation of Fc gamma receptor IIIA alpha (CD16-II) on natural killer cells induced by anti-CD16 mAb is independent of protein tyrosine kinases and protein kinase C.
Topics: Alkaloids; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Down-Regulation; Genistein; Humans; In Vitro Techniques; Isoflavones; Killer Cells, Natural; Lectins, C-Type; Metalloendopeptidases; Phenanthrolines; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, IgG; Receptors, Interleukin-2; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zinc | 1994 |
Effect of inhibitors of distinct signalling pathways on neutrophil Q2- generation in response to tumor necrosis factor-alpha, and antibodies against CD18 and CD11a: evidence for a common and unique pattern of sensitivity to wortmannin and protein tyrosine
Topics: Alkaloids; Androstadienes; Antigens, CD; CD18 Antigens; Genistein; Integrins; Isoflavones; Lymphocyte Function-Associated Antigen-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella; Wortmannin | 1993 |
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Lung Neoplasms; Membrane Glycoproteins; Neoplasms; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation.
Topics: Calcimycin; Catechols; Cells, Cultured; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; Humans; Isoflavones; Keratinocytes; Kinetics; Nitriles; Protein-Tyrosine Kinases; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tyrphostins; Ultraviolet Rays | 1994 |
Stimulation of low-density lipoprotein uptake in HepG2 cells by epidermal growth factor via a tyrosine kinase-dependent, but protein kinase C-independent, mechanism.
Topics: Acetates; Cholesterol; Enzyme Activation; Epidermal Growth Factor; Esterification; Genistein; Humans; Indoles; Isoflavones; Lipoproteins, LDL; Protein Kinase C; Protein-Tyrosine Kinases; Sucrose; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
Topics: Concanavalin A; Genistein; Humans; Hydroquinones; Ionomycin; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylation; Protein Kinase C; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1993 |
Stimulation of the human neutrophil respiratory burst by formyl peptides is primed by a protein kinase inhibitor, staurosporine.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Genistein; Humans; Isoflavones; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Respiratory Burst; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
1,25-Dihydroxyvitamin D3 and macrophage colony-stimulating factor-1 synergistically phosphorylate talin.
Topics: Alkaloids; Animals; Calcitriol; Cell Line; Drug Synergism; Genistein; Isoflavones; L Cells; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Staurosporine; Talin; Tetradecanoylphorbol Acetate | 1993 |
[Effect of epidermal growth factor (EGF) on mouse sperm capacitation].
Topics: Animals; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Mice; Mice, Inbred Strains; Phosphorylation; Protein-Tyrosine Kinases; Sperm Capacitation; Stimulation, Chemical; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Enhancement of A23187-induced arachidonic acid liberation by vasopressin is sensitive to genistein in rabbit platelets.
Topics: Acetophenones; Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Drug Synergism; Epinephrine; Genistein; Isoflavones; Phospholipases A; Phospholipases A2; Platelet Aggregation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled m1 muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Brain; Calcimycin; Calcium; Cell Line; Embryo, Mammalian; Embryo, Nonmammalian; Female; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Kidney; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Neuroblastoma; Oocytes; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Xenopus | 1993 |
Modulation of superoxide generation in in vivo lipopolysaccharide-primed Kupffer cells by staurosporine, okadaic acid, manoalide, arachidonic acid, genistein and sodium orthovanadate.
Topics: Alkaloids; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Enzyme Inhibitors; Ethers, Cyclic; Genistein; In Vitro Techniques; Isoflavones; Kupffer Cells; Lipopolysaccharides; Male; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Vanadates | 1994 |
Basic FGF activates phospholipase D in endothelial cells in the absence of inositol-lipid hydrolysis.
Topics: Calcium; Cell Division; Cells, Cultured; Endothelium, Vascular; Extracellular Space; Fibroblast Growth Factor 2; Genistein; Glycerophospholipids; Humans; Hydrolysis; Inositol; Isoflavones; Lipid Metabolism; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1994 |
The interleukin-6 (IL-6)/IL-6-receptor system induces human chorionic gonadotropin production by activating tyrosine kinase-dependent signal transduction pathway different from pathways triggered by protein kinase activators including gonadotropin releasi
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Calcimycin; Calmodulin; Chorionic Gonadotropin; Enzyme Activation; Female; Genistein; Gonadotropin-Releasing Hormone; Humans; Interleukin-1; Interleukin-6; Isoflavones; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Immunologic; Receptors, Interleukin-6; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Necrosis Factor-alpha | 1993 |
Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II.
Topics: Apoptosis; Benzoquinones; Cells, Cultured; Chromatin; DNA Damage; Etoposide; Genistein; Humans; Immunophenotyping; Infant; Isoflavones; Kinetics; Lactams, Macrocyclic; Methylprednisolone; Novobiocin; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Topoisomerase II Inhibitors | 1993 |
Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein.
Topics: Animals; Anticarcinogenic Agents; Edema; Female; Free Radical Scavengers; Genistein; Humans; Hydrogen Peroxide; Isoflavones; Mice; Neutrophils; Reactive Oxygen Species; Skin; Skin Diseases; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Tyrosine kinase activity is involved in the protein kinase C induced expression of interleukin-1 beta gene in monocytic cells.
Topics: Cell Line; Enhancer Elements, Genetic; Gene Expression; Genistein; Interleukin-1; Isoflavones; Monocytes; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Regulation of CD69 expression on human natural killer cells: differential involvement of protein kinase C and protein tyrosine kinases.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Genistein; Humans; Isoflavones; Killer Cells, Natural; Lectins, C-Type; Lymphocyte Activation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, IgG; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Epidermal growth factor is a potent inhibitor of renin secretion.
Topics: Angiotensin II; Animals; Cyclooxygenase Inhibitors; Epidermal Growth Factor; Genistein; Isoflavones; Male; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Renin; Tetradecanoylphorbol Acetate | 1993 |
Protein tyrosine phosphorylation induced by epidermal growth factor and insulin-like growth factor-I in a rat clonal dental pulp-cell line.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Dental Pulp; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isoflavones; Mice; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells.
Topics: Acetamides; Biomarkers; Blood Proteins; Cell Differentiation; Cycloheximide; Cytokines; Dactinomycin; Defensins; Dimethyl Sulfoxide; Dimethylformamide; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Genistein; Granulocyte Colony-Stimulating Factor; Granulocytes; HL-60 Cells; Humans; Interferon-gamma; Isoflavones; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphocytes; Lymphoma, Large B-Cell, Diffuse; Neoplasm Proteins; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Role of tyrosine kinase in insulin release in an insulin secreting cell line (INS-1).
Topics: Cell Line; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Estrogens, Non-Steroidal; Genistein; Glucose; Humans; Insulin; Insulin Secretion; Insulin-Like Growth Factor I; Islets of Langerhans; Isoflavones; Nitriles; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrphostins | 1995 |
Activation of human endometrial phospholipase D by bradykinin.
Topics: Adult; Alkaloids; Bradykinin; Cells, Cultured; DNA; Drug Synergism; Endometrium; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Glycerophospholipids; Humans; Inositol Phosphates; Isoflavones; Kinetics; Middle Aged; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Stromal Cells; Tetradecanoylphorbol Acetate | 1995 |
Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: involvement of protein tyrosine kinase and protein kinase C.
Topics: Animals; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; Enzyme Activation; Enzyme Inhibitors; Genistein; Hepatocyte Growth Factor; Isoflavones; Liver; Male; Mitogen-Activated Protein Kinase Kinases; Phospholipases A; Phospholipases A2; Prostaglandins; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Quinacrine; ras Proteins; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1996 |
Extracellular ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fc receptors.
Topics: Adenosine Triphosphate; Animals; beta-N-Acetylhexosaminidases; Calcium; Cell Line; Cross-Linking Reagents; Extracellular Space; Genistein; Histamine Release; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Isoflavones; Mast Cells; Mice; Mice, Inbred A; Mice, Inbred C57BL; Naphthalenes; Phosphorylation; Protein Kinase C; Receptors, Fc; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine | 1996 |
Mitogenic effect of erythropoietin on neonatal rat cardiomyocytes: signal transduction pathways.
Topics: 4-Nitrophenylphosphatase; Animals; Antibodies; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; Erythropoietin; Genistein; Humans; Isoflavones; Mitogens; Myocardium; Ouabain; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Cell Line; Cell Nucleus; Dactinomycin; DNA Probes; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Interleukin-11; Isoflavones; Isoquinolines; Kinetics; Luciferases; Naphthalenes; Open Reading Frames; Piperazines; Primates; Protein Kinase C; Recombinant Fusion Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection | 1996 |
Tyrosine kinase is involved in angiotensin II-stimulated phospholipase D activation in aortic smooth muscle cells: function of Ca2+ influx.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Genistein; Inositol Phosphates; Ionophores; Isoflavones; Membrane Lipids; Muscle Proteins; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity by genistein, a tyrosine kinase inhibitor.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Survival; Enzyme Inhibitors; Genistein; Haplorhini; Isoflavones; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1996 |
Regulation of N-acetylglucosaminyltransferase V by protein kinases.
Topics: Amino Acid Sequence; Bucladesine; Carbohydrate Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Humans; Isoflavones; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Protein Kinase C; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1995 |
Enhanced expression of GTP-binding proteins in differentiated U937 monocytic cells: possible involvement of tyrosine kinase and protein kinase C.
Topics: Alkaloids; Cell Differentiation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Monocytes; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Control of SHB gene expression by protein phosphorylation.
Topics: 3T3 Cells; Animals; Becaplermin; Enzyme Inhibitors; Ethers, Cyclic; Gene Expression Regulation; Genistein; Isoflavones; Mice; Nitriles; Okadaic Acid; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrphostins | 1996 |
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.
Topics: Alkaloids; Base Sequence; Calcimycin; Cell Hypoxia; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; I-kappa B Proteins; Ionophores; Isoflavones; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Kinase C; Protein Tyrosine Phosphatases; src-Family Kinases; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Substance P activates the release of histamine from human skin mast cells through a pertussis toxin-sensitive and protein kinase C-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Anti-Idiotypic; Bryostatins; Cyclic AMP; Enzyme Activation; Genistein; GTP-Binding Proteins; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Isoflavones; Lactones; Macrolides; Mast Cells; Pertussis Toxin; Protease Inhibitors; Protein Kinase C; Skin; Skin Physiological Phenomena; Substance P; Sulfones; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
Rapid activation of mitogen-activated protein kinase and p21ras by prolactin and interleukin 2 in rat Nb2 node lymphoma cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Activation; Enzyme Inhibitors; Genistein; Guanosine Triphosphate; Interleukin-2; Isoflavones; Lymph Nodes; Lymphoma, T-Cell; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Signal transduction by basic fibroblast growth factor in rat osteoblastic Py1a cells.
Topics: Analysis of Variance; Animals; Cell Line; DNA; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Genes, fos; Genistein; Humans; Immunoblotting; Isoflavones; Mitogens; Molecular Weight; Osteoblasts; Phosphorylation; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine | 1996 |
Ionomycin-stimulated arachidonic acid release in human platelets: a role for protein kinase C and tyrosine phosphorylation.
Topics: Arachidonic Acid; Blood Platelets; Calcium; Collagen; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Ionophores; Isoflavones; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Theileria parva sporozoite entry into bovine lymphocytes involves both parasite and host cell signal transduction processes.
Topics: Adenosine; Animals; Cattle; Down-Regulation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Isoflavones; Lymphocytes; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Suramin; Tetradecanoylphorbol Acetate; Theileria parva; Trypanocidal Agents; Type C Phospholipases | 1996 |
Protein kinase C potentiation of the tyrosine kinase inhibitor-stimulated cyclic GMP production in rat pinealocytes.
Topics: Animals; Calcium; Cyclic GMP; Genistein; Isoflavones; Male; Pineal Gland; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Genistein; Insulin; Isoflavones; Mitogen-Activated Protein Kinase 1; Myocardium; Polyenes; Polyunsaturated Alkamides; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase Cs and tyrosine kinases in permissive action of prostacyclin on cerebrovascular regulation in newborn pigs.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Arterioles; Benzoquinones; Down-Regulation; Epoprostenol; Genistein; Hypercapnia; Isoflavones; Lactams, Macrocyclic; Pia Mater; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Swine; Tetradecanoylphorbol Acetate; Vasodilation | 1997 |
Phorbol ester enhancement of IL-3-dependent proliferation of primitive hematopoietic progenitors of mice in culture.
Topics: Animals; Bone Marrow; Cell Division; Cells, Cultured; Fluorouracil; Genistein; Hematopoietic Stem Cells; Interleukin-3; Isoflavones; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Tyrosine kinase inhibition decreases Muc-1 expression in mouse epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Antibodies; Base Sequence; Cell Line; Cells, Cultured; Conserved Sequence; DNA Primers; Enzyme Inhibitors; Epithelium; Female; Gene Expression; Genistein; Isoflavones; Isoquinolines; Kinetics; Mammary Glands, Animal; Mice; Molecular Sequence Data; Mucin-1; Naphthalenes; Peptide Fragments; Polymerase Chain Reaction; Pregnancy; Protein Biosynthesis; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Uterus | 1997 |
Tumor necrosis factor-alpha regulates plasminogen activator inhibitor-1 in rat testicular peritubular cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; Isoflavones; Male; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Staurosporine; Testis; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Up-Regulation | 1997 |
Phospholipase D activity in the Tetrahymena pyriformis GL.
Topics: Animals; Biological Evolution; Carcinogens; Enzyme Inhibitors; Fluorides, Topical; Genistein; Isoflavones; Naphthalenes; Palmitic Acid; Pertussis Toxin; Phospholipase D; Protein Kinase C; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tetrahymena pyriformis; Tritium; Vanadates; Virulence Factors, Bordetella | 1997 |
Activation of G-proteins with AIF-4 induces LFA-1-mediated adhesion of T-cell hybridoma cells to ICAM-1 by signal pathways that differ from phorbol ester- and manganese-induced adhesion.
Topics: Aluminum Compounds; Androstadienes; Animals; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fluorides; Genistein; GTP-Binding Proteins; Humans; Hybridomas; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lymphocyte Function-Associated Antigen-1; Maleimides; Manganese; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
Protein tyrosine kinase activity regulates nitric oxide synthase induction in rat hepatocytes.
Topics: Animals; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Genistein; Interleukin-1; Isoflavones; Liver; Male; Nitric Oxide Synthase; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Xanthine; Xanthine Oxidase; Xanthines | 1997 |
Lead may affect glucocorticoid signal transduction in cultured hepatoma cells through inhibition of protein kinase C.
Topics: Animals; Blotting, Western; Calcium Chloride; Carcinoma, Hepatocellular; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Glucocorticoids; Isoenzymes; Isoflavones; Lead; Liver Neoplasms; Organometallic Compounds; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine Transaminase | 1997 |
The enhancement by wortmannin of protein kinase C-dependent activation of phospholipase D in vascular endothelial cells.
Topics: Androstadienes; Animals; Cattle; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Genistein; Glycerophospholipids; Isoenzymes; Isoflavones; Morpholines; Oxidants; Phosphatidic Acids; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorus Radioisotopes; Protein Kinase C; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Wortmannin | 1997 |
Regulation of luminol-dependent chemiluminescence and degranulation by bovine neutrophils stimulated with opsonized zymosan.
Topics: Adrenergic beta-Antagonists; Animals; Cattle; Cell Degranulation; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoflavones; Luminescent Measurements; Luminol; Neutrophils; Pertussis Toxin; Propranolol; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Zymosan | 1996 |
Effects of respiratory burst inhibitors on nitric oxide production by human neutrophils.
Topics: Adenylyl Cyclases; Electrochemistry; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Humans; Hydrogen Peroxide; Isoflavones; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Pertussis Toxin; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1997 |
A phospholipase D and protein kinase C inhibitor blocks the spreading of murine mammary adenocarcinoma cells altering f-actin and beta1-integrin point contact distribution.
Topics: 1-Butanol; Actins; Adenocarcinoma; Animals; Butanols; Cell Adhesion; Cell Division; Enzyme Inhibitors; Genistein; Integrin beta1; Isoflavones; Mammary Neoplasms, Experimental; Mice; Microscopy, Fluorescence; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Hydrogen peroxide-induced phospholipase D activation in rat pheochromocytoma PC12 cells: possible involvement of Ca2+-dependent protein tyrosine kinase.
Topics: Animals; Benzoquinones; Blotting, Western; Calcimycin; Calcium; Cinnamates; Enzyme Activation; Enzyme Inhibitors; Genistein; Hydrogen Peroxide; Isoflavones; Lactams, Macrocyclic; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sulfides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
p70s6k is activated by CCK in rat pancreatic acini.
Topics: Amino Acid Sequence; Androstadienes; Animals; Bombesin; Carbachol; Cells, Cultured; Cholecystokinin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Genistein; Ionomycin; Isoflavones; Kinetics; Male; Molecular Sequence Data; Pancreas; Peptides; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus; Substrate Specificity; Tacrolimus; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide; Wortmannin | 1997 |
VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways.
Topics: 3T3 Cells; Acetylcysteine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Hypoxia; Cell Transformation, Neoplastic; DNA-Binding Proteins; Endothelial Growth Factors; Genes, ras; Genistein; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Isoflavones; Lymphokines; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; ras Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Ultraviolet Rays; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Opposite effect of intracellular Ca2+ and protein kinase C on the expression of inwardly rectifying K+ channel 1 in mouse skeletal muscle.
Topics: Animals; Calcium; Cycloheximide; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Genistein; Ionomycin; Isoflavones; Mice; Muscle Denervation; Muscle, Skeletal; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation | 1997 |
Mechanisms of serotonin-induced Ca2+ responses in mesangial cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Enzyme Activation; Genistein; Glomerular Mesangium; Isoflavones; Rats; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate; Type C Phospholipases; Verapamil | 1997 |
Role of protein kinases in the in vitro differentiation of human epidermal HaCaT cells.
Topics: Adenine; Cell Differentiation; Cell Line; Enzyme Inhibitors; Epidermal Cells; Epidermis; Genistein; Humans; Indoles; Isoenzymes; Isoflavones; Keratinocytes; Maleimides; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction.
Topics: Animals; Cell Line; Cholera Toxin; Endotoxins; Enzyme Inhibitors; Escherichia coli; Genistein; GTP-Binding Proteins; Guanosine Diphosphate; Isoflavones; Kinetics; Lipopolysaccharides; Macrophages; Mice; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Pertussis Toxin; Phospholipid Ethers; Polymerase Chain Reaction; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Inflammatory potency of activin A. Effect on prostanoid and nitric oxide formation.
Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Inflammation; Inhibins; Interleukin-2; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; Tyrphostins | 1997 |
Effects of inhibitors of signal transduction pathways on transforming growth factor beta1 and osteogenic protein-1-induced insulinlike growth factor binding protein-3 expression in human bone cells.
Topics: Bone and Bones; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cells, Cultured; Culture Media, Conditioned; Gene Expression Regulation; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 3; Isoflavones; Okadaic Acid; Osteoblasts; Phosphoprotein Phosphatases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured; Vanadates | 1997 |
Activation of granulocytes by phorbol-12-myristate-14-acetate (PMA) enhances phagocytosis of Streptococcus pyogenes.
Topics: Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Carrier Proteins; Enzyme Inhibitors; Flow Cytometry; Genistein; Granulocytes; Humans; In Vitro Techniques; Macrophage-1 Antigen; Neutrophils; Phagocytosis; Protein-Tyrosine Kinases; Streptococcus pyogenes; Tetradecanoylphorbol Acetate; Virulence | 1997 |
Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Cricetinae; Endothelin Receptor Antagonists; Endothelin-1; Fibroblasts; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Norepinephrine; Peptides, Cyclic; Phosphorylation; Rats; Receptor, Endothelin A; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Expression of p56lck in B-cell neoplasias.
Topics: Antibodies, Anti-Idiotypic; B-Lymphocytes; Burkitt Lymphoma; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; HeLa Cells; Hodgkin Disease; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphoma, B-Cell; Phosphorylation; Protein Kinase C; Staphylococcus aureus; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Helicobacter pylori induces interleukin-8 expression in endothelial cells and the signal pathway is protein tyrosine kinase dependent.
Topics: Bacterial Proteins; Bacterial Toxins; Benzoquinones; Cell Line; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cytotoxins; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Helicobacter pylori; Humans; Interleukin-8; Lactams, Macrocyclic; Lipopolysaccharides; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Prostaglandin E2 stimulates sodium-dependent phosphate transport in osteoblastic cells via a protein kinase C-mediated pathway.
Topics: Androstadienes; Animals; Biological Transport; Cells, Cultured; Dinoprostone; DNA; Genistein; Indomethacin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Osteoblasts; Phosphates; Protein Kinase C; Rats; Sodium; Tetradecanoylphorbol Acetate; Wortmannin | 1998 |
Positive and negative controls by protein kinases of sodium-dependent Ca2+ efflux from cultured bovine adrenal chromaffin cells stimulated by lysophosphatidic acid.
Topics: Adrenal Glands; Animals; Calcium; Carbachol; Catecholamines; Cattle; Chromaffin Cells; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; Genistein; Lysophospholipids; Naphthalenes; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Sodium; Sodium-Calcium Exchanger; Staurosporine; Structure-Activity Relationship; Suramin; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
Store-operated Ca2+ entry in insulin-releasing pancreatic beta-cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Carbachol; Cells, Cultured; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Gallopamil; Genistein; Insulin; Islets of Langerhans; Lanthanum; Manganese; Mice; Mice, Obese; Okadaic Acid; Pancreas; Phosphoprotein Phosphatases; Protein-Tyrosine Kinases; Strontium; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1997 |
The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway.
Topics: Antineoplastic Agents; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Squamous Cell; Enzyme Activation; Enzyme Induction; Genistein; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Phosphotyrosine; Protein Kinase C; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1998 |
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart.
Topics: Alkaloids; Animals; Anisomycin; Benzophenanthridines; Enzyme Activation; Enzyme Inhibitors; Female; Genistein; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Mitogen-Activated Protein Kinase Kinases; Myocardial Infarction; Myocardial Reperfusion Injury; Phenanthridines; Phenols; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression.
Topics: Biological Transport, Active; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Genistein; Humans; Hydroquinones; I-kappa B Proteins; Interleukin-1; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 1998 |
Protein tyrosine phosphorylation and calcium signaling in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; Genistein; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Mycoplasma salivarium induces interleukin-6 and interleukin-8 in human gingival fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Cell Fractionation; Cell Line; Densitometry; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression; Genistein; Gingiva; Humans; Interleukin-6; Interleukin-8; Mice; Mycoplasma; Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate | 1997 |
Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway.
Topics: Base Sequence; Benzoquinones; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Dactinomycin; DNA, Complementary; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Genistein; Humans; Hydroquinones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; NF-kappa B; Okadaic Acid; Phenols; Proto-Oncogene Proteins c-raf; Quinones; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription Factor AP-1; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1998 |
Regulation of alphaIIb beta3 function in human B lymphocytes.
Topics: B-Lymphocytes; Cell Adhesion; Cytochalasin D; Enzyme Inhibitors; Fibrinogen; Flow Cytometry; Gene Expression Regulation; Genistein; GTP-Binding Proteins; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
1alpha,25(OH)2-vitamin D3 signaling in chick enterocytes: enhancement of tyrosine phosphorylation and rapid stimulation of mitogen-activated protein (MAP) kinase.
Topics: Animals; Calcitriol; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chickens; Duodenum; Enzyme Activation; Enzyme Inhibitors; Genistein; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Different effect of diastereoisomers of L-cystathionine sulfoxide on the stimulus coupled responses of human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Metabolism, Inborn Errors; Cystathionine; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Oncostatin M regulates endothelin-1 production in human endothelial cells.
Topics: Benzoquinones; Cell Division; Cell Survival; Cells, Cultured; Drug Interactions; Endothelin-1; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Growth Inhibitors; Humans; Isoflavones; Lactams, Macrocyclic; Oncostatin M; Peptides; Protein Precursors; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Umbilical Veins | 1998 |
Induction of proliferation in isolated guinea pig gastric epithelium during restitution after superficial injury.
Topics: Animals; Carcinogens; Cell Division; Cycloheximide; Enzyme Inhibitors; Epithelial Cells; Gastric Mucosa; Genistein; Guinea Pigs; Ki-67 Antigen; Protein Synthesis Inhibitors; Signal Transduction; Sodium Chloride; Tetradecanoylphorbol Acetate; Wound Healing | 1998 |
Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation.
Topics: Antiemetics; Biological Transport; Bucladesine; Calcium; Calmodulin; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Flavins; Genistein; Humans; Imidazoles; Protein Kinase C; Riboflavin; Signal Transduction; Tetradecanoylphorbol Acetate; Trifluoperazine; Tritium; Tumor Cells, Cultured; Vanadates | 1998 |
Activation of the neutrophil respiratory burst requires both intracellular and extracellular calcium.
Topics: Calcium; Egtazic Acid; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Vanadates | 1997 |
Hypoxia and endothelin-1 induce VEGF production in human vascular smooth muscle cells.
Topics: Cell Hypoxia; Cells, Cultured; Cobalt; Endothelial Growth Factors; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Genistein; Growth Inhibitors; Humans; Lymphokines; Muscle, Smooth, Vascular; RNA, Messenger; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration.
Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Benzoquinones; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Enzyme Inhibitors; Fibroblast Growth Factor 2; Genistein; Lactams, Macrocyclic; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Phenanthridines; Phenols; Pigment Epithelium of Eye; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rats; Reference Values; Retinal Degeneration; Rifabutin; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Are tyrosine phosphorylation of p125(FAK) and paxillin or the small GTP binding protein, rho, needed for CCK-stimulated pancreatic amylase secretion?
Topics: ADP Ribose Transferases; Amylases; Animals; Botulinum Toxins; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin D; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; GTP-Binding Proteins; Male; Pancreas; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; DNA Adducts; Down-Regulation; Drug Screening Assays, Antitumor; Female; Genistein; Hydrogen Peroxide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Peroxidase; Protein-Tyrosine Kinases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Effects of genistein and staurosporine on angiotensin II-induced DNA synthesis, protein synthesis and mitogen-activated protein kinase activation in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Genistein; In Vitro Techniques; Male; Muscle Proteins; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1998 |
Involvement of protein kinases and phosphatases in tyrosine phosphorylation of PKCdelta in rat parotid acinar cells exposed to secretory stimuli.
Topics: Animals; Carbachol; Carcinogens; Enzyme Inhibitors; Epithelial Cells; Genistein; Isoenzymes; Muscarinic Agonists; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
On the role of c-Jun in the induction of PAI-1 gene expression by phorbol ester, serum, and IL-1alpha in HepG2 cells.
Topics: Binding Sites; Blood; Blotting, Northern; Carcinoma, Hepatocellular; Enzyme Inhibitors; Gene Expression; Genistein; Humans; Immunosorbent Techniques; Interleukin-1; Liver; Liver Neoplasms; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 1999 |
Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Glucose; Insulin; Insulin Secretion; Ion Transport; Islets of Langerhans; Isoflavones; Leupeptins; Phenylmethylsulfonyl Fluoride; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1999 |
D-cystathionine ketimine and L-cystathionine ketimine enhance superoxide generation by human neutrophils in a different manner.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Benzoquinones; Cystathionine; Enzyme Inhibitors; Genistein; Humans; Lactams, Macrocyclic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Serine; Staurosporine; Stereoisomerism; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1999 |
Activation of mitogen activated protein kinase in human platelets by genistein.
Topics: Animals; Blood Platelets; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinase 1; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Staurosporine; Swine; Tetradecanoylphorbol Acetate | 1999 |
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
Topics: Alkaloids; Amino Acid Sequence; Animals; Benzophenanthridines; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Isoflavones; Lysophospholipids; meta-Aminobenzoates; Mice; Mice, Knockout; Microinjections; Molecular Sequence Data; Muscarine; Nerve Tissue Proteins; Neuronal Plasticity; Oocytes; Patch-Clamp Techniques; Phenanthridines; Phenols; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins pp60(c-src); Pyramidal Cells; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Salicylates; Signal Transduction; Tetradecanoylphorbol Acetate; Xenopus laevis | 1999 |
LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent.
Topics: Cells, Cultured; DNA; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Lipopolysaccharides; Maleimides; Monocytes; NF-kappa B; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbon Radioisotopes; Carcinogens; Cardiomegaly; Cells, Cultured; Chromones; Creatine Kinase; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Heart Ventricles; Indoles; Isoenzymes; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle Fibers, Skeletal; Myocardium; Phenylephrine; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Wortmannin | 1999 |
Effect of water extracts of Rhizopus delemar on the stimulus coupled responses of neutrophils and their modulation by various protein kinase inhibitors.
Topics: Enzyme Inhibitors; Genistein; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Protein Kinase Inhibitors; Rhizopus; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Water | 1999 |
Lysophosphatidylcholine stimulates phospholipase D activity in mouse peritoneal macrophages.
Topics: Acetylation; Animals; Azepines; Cell Line; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Genistein; Lysophosphatidylcholines; Lysophospholipids; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Phosphotyrosine; Platelet Membrane Glycoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
The small GTP-binding proteins Rho and Rac induce T cell adhesion to the mucosal addressin MAdCAM-1 in a hierarchical fashion.
Topics: 3T3 Cells; Aluminum Compounds; Animals; Cell Adhesion; Cell Adhesion Molecules; Complement C3; Electroporation; Fluorides; Genistein; Immunoglobulins; Integrins; Lymphoma, T-Cell; Mice; Mucoproteins; rac GTP-Binding Proteins; Receptors, Lymphocyte Homing; rho GTP-Binding Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Protein synthesis-dependent and -independent induction of p69 2'-5'-oligoadenylate synthetase by interferon-alpha.
Topics: 2',5'-Oligoadenylate Synthetase; Burkitt Lymphoma; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Induction; Genistein; Humans; Interferon-alpha; Isoenzymes; Molecular Weight; Protein Biosynthesis; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Intracellular regulation of estradiol and progesterone production by cultured bovine granulosa cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Genistein; Granulosa Cells; Progesterone; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, FSH; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
The effect of PKC activation on the survival of rat retinal ganglion cells in culture.
Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Cell Division; Cell Survival; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Floxuridine; Genistein; Neuroglia; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Retinal Ganglion Cells; Superior Colliculi; Tetradecanoylphorbol Acetate | 2000 |
Angiotensin II and PDGF-BB stimulate beta(1)-integrin-mediated adhesion and spreading in human VSMCs.
Topics: Angiotensin II; Anticoagulants; Antigens, CD; Antihypertensive Agents; Aorta; Becaplermin; Biphenyl Compounds; Carcinogens; Cell Adhesion; Cell Movement; Collagen; Culture Techniques; Enzyme Inhibitors; Fibronectins; Flow Cytometry; Gene Expression; Genistein; Humans; Iliac Artery; Imidazoles; Integrin alpha5; Integrin beta1; Irbesartan; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Vasoconstrictor Agents | 2000 |
Interleukin-1beta regulates CFTR expression in human intestinal T84 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Benzoquinones; Cell Line; Colon; Colonic Neoplasms; Cycloheximide; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Genistein; Humans; Indoles; Interleukin-1; Lactams, Macrocyclic; Maleimides; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Quinones; Rifabutin; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2000 |
Genistein augments prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chlorides; Cyclic GMP; Dinoprostone; Drug Synergism; Electric Impedance; Female; Genistein; Ileum; Intestinal Mucosa; Ischemia; Male; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Swine; Tetradecanoylphorbol Acetate; Tritium | 2000 |
Cross-linking of CD4 induces cytoskeletal association of CD4 and p56lck.
Topics: CD4 Antigens; Cross-Linking Reagents; Cytoskeleton; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Genistein; Humans; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Protein Binding; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 2000 |
Involvement of the mitogen-activated protein (MAP) kinase signalling pathway in host cell invasion by Toxoplasma gondii.
Topics: Animals; Bombesin; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Mitogen-Activated Protein Kinases; Models, Biological; Signal Transduction; Tetradecanoylphorbol Acetate; Toxoplasma | 2000 |
Sevoflurane stimulates inositol 1,4,5-trisphosphate in skeletal muscle.
Topics: Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Genistein; GTP-Binding Proteins; Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Methyl Ethers; Muscle, Skeletal; ortho-Aminobenzoates; Phospholipases A; Protein-Tyrosine Kinases; Pyrrolidinones; Rats; Sevoflurane; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases; Tyrphostins | 2000 |
A unique monoclonal antibody mNI-11 rapidly enhances spread formation in human umbilical vein endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Antibodies, Monoclonal; Antibody Specificity; Calcium; Calmodulin; Cell Adhesion Molecules; Cell Size; Cells, Cultured; Chelating Agents; Cycloheximide; Cytochalasin D; Edetic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epitopes; Flow Cytometry; Genistein; HL-60 Cells; Humans; K562 Cells; Microtubules; Nocodazole; Protein Kinase C; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells; Umbilical Veins | 2000 |
TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway.
Topics: Benzoquinones; Cell Nucleus; Cyclooxygenase 2; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Epithelial Cells; Estrenes; Gene Expression Regulation; Genistein; Humans; I-kappa B Kinase; Isoenzymes; Lactams, Macrocyclic; Lung; Membrane Proteins; Mutagenesis, Site-Directed; NF-kappa B; NF-kappaB-Inducing Kinase; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase C gamma; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrrolidines; Pyrrolidinones; Quinones; Rifabutin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thiocarbamates; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Type C Phospholipases | 2000 |
Protein tyrosine kinase is not involved in the infarct size-limiting effect of ischemic preconditioning in canine hearts.
Topics: 5'-Nucleotidase; Animals; Carcinogens; Dogs; Enzyme Activation; Enzyme Inhibitors; Genistein; Ischemic Preconditioning; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phenols; Protein Kinase C; src-Family Kinases; Tetradecanoylphorbol Acetate | 2000 |
Endotoxin causes phosphorylation of MARCKS in pulmonary vascular endothelial cells.
Topics: Animals; Cattle; Cell Membrane; Cells, Cultured; Cytosol; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Gram-Negative Bacterial Infections; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Myosin Light Chains; Myristoylated Alanine-Rich C Kinase Substrate; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Pyridines; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Thrombin | 2000 |
Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways.
Topics: Chemokine CCL4; Chemokines; Cyclic AMP; Dexamethasone; Enzyme Inhibitors; Genistein; Humans; Imidazoles; Inflammation; Interleukin-8; Macrophage Inflammatory Proteins; Mitogen-Activated Protein Kinases; Monocytes; Nitric Oxide; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Triazenes; U937 Cells | 2000 |
Filopodial behavior is dependent on the phosphorylation state of neuronal growth cones.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Carrier Proteins; Cells, Cultured; Cerebrosides; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Genistein; Growth Cones; Indole Alkaloids; Intracellular Signaling Peptides and Proteins; Models, Biological; Myosin-Light-Chain Kinase; Naphthalenes; Neurons; Okadaic Acid; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pseudopodia; Signal Transduction; Snails; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 2000 |
Mac-1-dependent tyrosine phosphorylation during neutrophil adhesion.
Topics: Antibodies, Monoclonal; Cell Adhesion; Cytochalasin B; Enzyme Inhibitors; Fibrinogen; Genistein; Glutathione Transferase; Humans; In Vitro Techniques; Interleukin-8; Kinetics; Macrophage-1 Antigen; Neutrophil Activation; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; src Homology Domains; Staurosporine; Tetradecanoylphorbol Acetate; Vanadates | 2001 |
Characterization of Na+-coupled glutamate/aspartate transport by a rat brain astrocyte line expressing GLAST and EAAC1.
Topics: Alanine; Amino Acid Transport System X-AG; Animals; Aspartic Acid; Astrocytes; ATP-Binding Cassette Transporters; Blotting, Western; Carrier Proteins; Cell Line; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Ganglionic Stimulants; Genistein; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ionophores; Kainic Acid; Protein Isoforms; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sodium; Symporters; Telencephalon; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Sustained norepinephrine stimulation induces different regulation of expression in three alpha1-adrenoceptor subtypes.
Topics: Cell Line; Egtazic Acid; Genistein; Humans; Indoles; Kidney; Norepinephrine; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tyrphostins | 2001 |
Soy isoflavonoids and cancer -- metabolism at the target site.
Topics: Anticarcinogenic Agents; Chromatography, Liquid; Dose-Response Relationship, Drug; Genistein; Humans; Hypochlorous Acid; Isoflavones; Male; Mass Spectrometry; Middle Aged; Neoplasms; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Urine | 2001 |
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells.
Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2001 |
[Autocrine regulation of hexokinase activity by HB-EGF in mesangial cells].
Topics: Animals; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Glomerular Mesangium; Heparin-binding EGF-like Growth Factor; Hexokinase; Intercellular Signaling Peptides and Proteins; Mice; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
[A study of different intracellular signal transduction pathways on phagocytosis of fibronectin by retinal pigment epithelial cells].
Topics: Androstadienes; Cells, Cultured; Enzyme Inhibitors; Fetus; Fibronectins; Genistein; Humans; Naphthalenes; Phagocytosis; Phosphoinositide-3 Kinase Inhibitors; Pigment Epithelium of Eye; Protein Kinase C; Protein-Tyrosine Kinases; Retina; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2001 |
Differential regulation of neutrophil phospholipase d activity and degranulation.
Topics: Catechin; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phosphatidic Acids; Phospholipase D; Resveratrol; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate | 2002 |
Modulation of the expression of GABA(A) receptors in rat cerebellar granule cells by protein tyrosine kinases and protein kinase C.
Topics: Animals; Cell Membrane; Cells, Cultured; Cerebellum; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Genistein; Microscopy, Confocal; Neurons; Protein Kinase C; Protein Subunits; Protein-Tyrosine Kinases; Rats; Receptors, GABA-A; Tetradecanoylphorbol Acetate | 2002 |
Cholinergic activation of glucose transport in bovine chromaffin cells involves calmodulin and protein kinase Czeta signaling.
Topics: Acetylcholine; Androstadienes; Animals; Biological Transport; Blotting, Northern; Calmodulin; Cattle; Cholinergic Agonists; Chromaffin Cells; Down-Regulation; Enzyme Inhibitors; Genistein; Glucose; Mitogen-Activated Protein Kinases; Models, Biological; Mutagens; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Wortmannin | 2002 |
Prolactin signaling in porcine adrenocortical cells: involvement of protein kinases.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Diglycerides; Enzyme Activators; Enzyme Inhibitors; Female; Genistein; Hydrocortisone; Ionomycin; Phorbol 12,13-Dibutyrate; Prolactin; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate | 2002 |
Effect of S-(1,2-dicarboxyethyl) glutathione and S-(1,2-dicarboxyethyl) cysteine on the stimulus-induced superoxide generation and tyrosyl phosphorylation of proteins in human neutrophils.
Topics: Arachidonic Acid; Blood Proteins; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Glutathione; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 2002 |
Regulation of CO production in cerebral microvessels of newborn pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminolevulinic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Capillaries; Carbon Monoxide; Catalysis; Cerebrovascular Circulation; Cytosol; Enzyme Inhibitors; Genistein; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Ionomycin; Ionophores; Phosphorylation; Photosensitizing Agents; Swine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 2003 |
Regulation of swelling-activated chloride channels in embryonic chick heart cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Actins; Animals; Cells, Cultured; Chick Embryo; Chloride Channels; Chlorpromazine; Enzyme Inhibitors; Genistein; Heart; Myocardium; Osmotic Pressure; Patch-Clamp Techniques; Protein Kinase C; Tetradecanoylphorbol Acetate | 2003 |
Phenylarsine oxide and H2O2 plus vanadate induce reverse translocation of phorbol-ester-activated PKCbetaII.
Topics: Animals; Arsenicals; Cell Membrane; Cells, Cultured; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Ethanol; Genistein; Hydrogen Peroxide; Neutrophils; Phospholipase D; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Transport; Protein Tyrosine Phosphatases; Sus scrofa; Tetradecanoylphorbol Acetate; Vanadates | 2003 |
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2003 |
Protein kinase C mediates induced secretion of vascular endothelial growth factor by human glioma cells.
Topics: Cell Line, Tumor; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; Glioma; Humans; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrphostins; Vascular Endothelial Growth Factor A | 2003 |
In vitro anti-inflammatory and pro-aggregative effects of a lipid compound, petrocortyne A, from marine sponges.
Topics: Acetylene; Animals; Anti-Inflammatory Agents; Autocrine Communication; Cell Adhesion Molecules; Cell Aggregation; Cell Differentiation; Cell Line; Fatty Alcohols; Genistein; Hepatocyte Growth Factor; Humans; Insulin-Like Growth Factor II; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; Nitric Oxide; Phosphorylation; Polymers; Polyynes; Porifera; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2003 |
Oxidative and adhesive responses of human neutrophils to nitrovasodilators in vitro: the role of protein kinases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Genistein; Humans; Molsidomine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide Donors; Nitroprusside; Oxidation-Reduction; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2003 |
Intracellular proteins involved in Porphyromonas gingivalis-induced opsonophagocytic activities of a murine macrophage cell line (RAW264.7 cells).
Topics: Animals; Cell Line; Cytochalasin D; Enzyme Inhibitors; Genistein; Macrophages; Mice; Nucleic Acid Synthesis Inhibitors; Phagocytosis; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Porphyromonas gingivalis; Protein Kinase C; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate | 2003 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Increase of C-type natriuretic peptide expression by serum and platelet-derived growth factor-BB in human aortic smooth muscle cells is dependent on protein kinase C activation.
Topics: Animals; Aorta; Becaplermin; Blood; Cells, Cultured; Culture Media; Endothelial Cells; Enzyme Activation; Gene Expression; Genistein; Humans; Indoles; Maleimides; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Rats; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Species Specificity; Tetradecanoylphorbol Acetate; Tyrphostins | 2006 |
Soya isoflavones suppress phorbol 12-myristate 13-acetate-induced COX-2 expression in MCF-7 cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Equol; Female; Genistein; Glycine max; Humans; Isoflavones; Membrane Proteins; Phytoestrogens; Plant Extracts; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate | 2006 |
Sensitization of the apoptotic effect of gamma-irradiation in genistein-pretreated CaSki cervical cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Dinoprostone; Female; Gamma Rays; Gene Expression Regulation, Neoplastic; Genistein; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Uterine Cervical Neoplasms | 2008 |
A high-throughput reporter gene assay to prove the ability of natural compounds to modulate glutathione peroxidase, superoxide dismutase and catalase gene promoters in V79 cells.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Carnitine; Catalase; Catechin; Cells, Cultured; Chromans; Cricetinae; Cricetulus; Genistein; Glutathione Peroxidase; Herbicides; Humans; Luciferases; Paraquat; Promoter Regions, Genetic; Quercetin; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vitamin B Complex | 2008 |
Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 2009 |
Anti-inflammatory and anticarcinogenic effect of genistein alone or in combination with capsaicin in TPA-treated rat mammary glands or mammary cancer cell line.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Blotting, Western; Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Drug Synergism; Female; Genistein; Humans; Mammary Glands, Animal; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2009 |
Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Transformation, Neoplastic; Epstein-Barr Virus Infections; Flavanones; Genistein; Herpesvirus 4, Human; Hesperidin; Isoflavones; Mice; Oleanolic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2011 |
Soy isoflavones (daidzein & genistein) inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cutaneous inflammation via modulation of COX-2 and NF-κB in Swiss albino mice.
Topics: Animals; Cell Proliferation; Cyclooxygenase 2; Dermatitis; Female; Genistein; Glycine max; Inflammation; Isoflavones; Ki-67 Antigen; Mice; NF-kappa B; Oxidative Stress; Plant Extracts; Skin; Tetradecanoylphorbol Acetate | 2012 |
Protective effect of fermented soybean dried extracts against TPA-induced oxidative stress in hairless mice skin.
Topics: Animals; Catalase; Desiccation; Female; Fermentation; Genistein; Glutathione; Glycine max; Hydrogen Peroxide; Male; Mice; Mice, Hairless; Oxidative Stress; Plant Extracts; Polyphenols; Protective Agents; Skin; Tetradecanoylphorbol Acetate | 2013 |
Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Genistein; Glycine max; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Invasiveness; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Phytotherapy; Plant Extracts; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2014 |
Genistein inhibits phorbol ester-induced NF-κB transcriptional activity and COX-2 expression by blocking the phosphorylation of p65/RelA in human mammary epithelial cells.
Topics: Active Transport, Cell Nucleus; Anticarcinogenic Agents; Carcinogens; Cell Line, Tumor; Cell Nucleus; CREB-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Enzymologic; Genistein; Humans; Mammary Glands, Human; Mutation; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2014 |
Genistein inhibits pro‑inflammatory cytokines in human mast cell activation through the inhibition of the ERK pathway.
Topics: Blotting, Western; Calcimycin; Cell Line, Tumor; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; MAP Kinase Signaling System; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phytoestrogens; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Phorbol-12-myristate-13-acetate (PMA) mediated transcriptional regulation of Oncostatin-M.
Topics: CCAAT-Enhancer-Binding Protein-beta; Genistein; Humans; Oncostatin M; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factor CHOP; Transcription, Genetic; U937 Cells | 2016 |
Biochanin A attenuates zymosan-induced arthritis in mice similarly to 17-β estradiol: an alternative to hormone replacement therapy?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis; Cytokines; DNA; Edema; Estradiol; Estrogen Replacement Therapy; Female; Genistein; Mice; Neutrophils; Ovariectomy; Tetradecanoylphorbol Acetate; Zymosan | 2020 |