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tetradecanoylphorbol acetate and geldanamycin

tetradecanoylphorbol acetate has been researched along with geldanamycin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's8 (72.73)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, JC; White, JR1
Blagosklonny, MV; Johnston, JF; Monia, BP; Mushinski, JF; Neckers, LM; Nguyen, P; Romanova, L; Schulte, TW; Trepel, J1
Cho, CH; Ding, SZ; Lam, SK1
Csermely, P; Schnaider, T; Somogyi, J; Szamel, M1
Grant, S; Vrana, JA1
Depledge, P; Dhanjal, N; Foxwell, B; Manic, A; Moore, M; Rawlins, P; Sadeghi, R; Wrigley, S1
Bakó, G; Csermely, P; Csongor, J; Illés, A; Kovács, I; Sipka, S; Szántó, S; Szegedi, G1
Broemer, M; Krappmann, D; Scheidereit, C1
Dong, J; Gunduz, M; Haisa, M; Kurebayashi, J; Matsuoka, J; Motoki, T; Nagatsuka, H; Nakajima, M; Naomoto, Y; Nobuhisa, T; Okawa, T; Sagara, J; Shirakawa, Y; Takaoka, M; Tanaka, N; Taniguchi, S; Tsujigiwa, H; Yamatsuji, T1
Ishikawa, A; Kizaki, H; Ohta, K; Okoshi, R; Sato, Y; Wakabayashi, M1
Gelb, MH; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM; Tucker, DE1

Other Studies

11 other study(ies) available for tetradecanoylphorbol acetate and geldanamycin

ArticleYear
Effect of protein kinase inhibitors on IL-8/NAP-1 release from human umbilical vein endothelial cells.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Alkaloids; Benzoquinones; Carbazoles; Cells, Cultured; Endothelium, Vascular; Humans; Indoles; Interleukin-1; Interleukin-8; Lactams, Macrocyclic; Protein Kinase Inhibitors; Pyrroles; Quinones; Recombinant Proteins; Rifabutin; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins

1993
Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway.
    Molecular and cellular biology, 1996, Volume: 16, Issue:10

    Topics: 3T3 Cells; Animals; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; DNA; Enzyme Inhibitors; Genes, Reporter; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Lactams, Macrocyclic; MAP Kinase Kinase Kinase 1; Mice; Oligonucleotides, Antisense; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Quinones; Rats; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection

1996
Helicobacter pylori induces interleukin-8 expression in endothelial cells and the signal pathway is protein tyrosine kinase dependent.
    Biochemical and biophysical research communications, 1997, Nov-26, Volume: 240, Issue:3

    Topics: Bacterial Proteins; Bacterial Toxins; Benzoquinones; Cell Line; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cytotoxins; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Helicobacter pylori; Humans; Interleukin-8; Lactams, Macrocyclic; Lipopolysaccharides; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1997
The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation.
    Cell stress & chaperones, 2000, Volume: 5, Issue:1

    Topics: Acyltransferases; Benzoquinones; Cell Division; DNA-Binding Proteins; Enzyme Inhibitors; Genes, Reporter; HSP90 Heat-Shock Proteins; Humans; Interleukin-2; Ionomycin; Jurkat Cells; Lactams, Macrocyclic; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Muromonab-CD3; Neoplasm Proteins; NFATC Transcription Factors; Nuclear Proteins; Proto-Oncogene Proteins c-raf; Quinones; Receptors, Interleukin-2; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors

2000
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Blood, 2001, Apr-01, Volume: 97, Issue:7

    Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins

2001
Differential regulation of CD3- and CD28-induced IL-2 and IFN-gamma production by a novel tyrosine kinase inhibitor XR774 from Cladosporium cf. cladosporioides.
    International immunopharmacology, 2001, Volume: 1, Issue:1

    Topics: Benzoquinones; CD28 Antigens; CD3 Complex; Cladosporium; Cyclosporine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorenes; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Jurkat Cells; Lactams, Macrocyclic; Protein-Tyrosine Kinases; Quinones; T-Lymphocytes; Tetradecanoylphorbol Acetate

2001
Inhibition of arachidonic acid release from human peripheral mononuclear cells by heat shock treatment and geldanamycin.
    Immunology letters, 2002, Oct-01, Volume: 83, Issue:3

    Topics: Arachidonic Acid; Benzoquinones; Calcimycin; Cells, Cultured; Enzyme Inhibitors; Heat-Shock Response; Hot Temperature; Humans; Ionophores; Lactams, Macrocyclic; Leukocytes, Mononuclear; Quinones; Tetradecanoylphorbol Acetate

2002
Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.
    Oncogene, 2004, Jul-08, Volume: 23, Issue:31

    Topics: Animals; Benzoquinones; Cell Line; Cell Line, Tumor; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Inflammation; Interleukin-1; Lactams, Macrocyclic; Lactones; Lymphoma; Macrolides; Molecular Chaperones; NF-kappa B; Phosphorylation; Precipitin Tests; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Quinones; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Ubiquitin

2004
Translocation of heparanase into nucleus results in cell differentiation.
    Cancer science, 2007, Volume: 98, Issue:4

    Topics: Benzoquinones; Cell Differentiation; Cell Nucleus; Cytoplasm; Glucuronidase; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Protein Transport; Tetradecanoylphorbol Acetate

2007
Geldanamycin, a heat-shock protein 90-binding agent, induces thymocyte apoptosis through destabilization of Lck in presence of 12-O-tetradecanoylphorbol 13-acetate.
    Biomedical research (Tokyo, Japan), 2007, Volume: 28, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Benzoquinones; Carcinogens; Enzyme Stability; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred BALB C; Protein Binding; Tetradecanoylphorbol Acetate; Thymus Gland

2007
Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.
    Journal of leukocyte biology, 2008, Volume: 84, Issue:3

    Topics: Animals; Arachidonic Acid; Benzoquinones; Calcimycin; Calcium; Carcinogens; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Golgi Apparatus; Green Fluorescent Proteins; Group IV Phospholipases A2; HSP90 Heat-Shock Proteins; Immunoblotting; Immunoprecipitation; Ionophores; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 10; NIH 3T3 Cells; Okadaic Acid; Phosphoamino Acids; Phosphorylation; Protein Transport; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan

2008