tetradecanoylphorbol acetate has been researched along with endothelin-1 in 112 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 51 (45.54) | 18.2507 |
| 2000's | 55 (49.11) | 29.6817 |
| 2010's | 6 (5.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horie, M; Kurokawa, K; Matsushita, Y; Ogata, E; Uchida, S; Yanagisawa, M | 1 |
| Fant, ME; Nanu, L | 1 |
| Arai, M; Demura, H; Emoto, N; Isozaki, O; Miyakawa, M; Sato, Y; Shizume, K; Tsushima, T | 1 |
| Huang, Y | 1 |
| Glass, PS; Xuan, YT | 1 |
| Horikawa, T; Morelli, JG; Norris, DA; Zekman, T | 1 |
| Lefer, AM; Murohara, T | 1 |
| Kawai, N; McCarron, RM; Spatz, M | 1 |
| Aikawa, R; Hiroi, Y; Komuro, I; Kudoh, S; Mizuno, T; Shiojima, I; Yamazaki, T; Yazaki, Y; Zou, Y | 1 |
| Bellosillo, B; Gil, J; Joaquin, M; Lange, AJ; Salvado, C; Tauler, A | 1 |
| Yamada, Y; Yokota, M | 1 |
| Bembry, J; Kawai, N; McCarron, RM; Merkel, N; Spatz, M | 1 |
| Cartledge, WA; Kumar, R; Lincoln, TM; Pandey, KN | 1 |
| Davies, EL; Fuller, SJ; Gillespie-Brown, J; Sun, H; Tonks, NK | 1 |
| Davies, EL; Fuller, SJ | 1 |
| Clerk, A; Sugden, PH | 2 |
| Murayama, T; Nomura, Y; Oda, H | 1 |
| Dellsperger, KC; Gutterman, DD; Miller, FJ | 1 |
| Bezstarosti, K; Dekkers, DH; Eskildsen-Helmond, YE; Lamers, JM; van Heugten, HA | 1 |
| García-Sáinz, JA; Medina, LC; Vázquez-Prado, J | 1 |
| Alper, SL; Izumo, S; Lee, IW; Malek, AM | 1 |
| Disashi, T; Inoue, J; Iwaoka, T; Kanesaka, Y; Naomi, S; Tokunaga, H; Tomita, K | 1 |
| Ferré, F; Fournier, T; Tertrin-Clary, C | 1 |
| Dibas, A; Prasanna, G; Tao, W; White, K; Yorio, T | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| Kirton, CA; Loutzenhiser, R | 1 |
| Fyhrquist, F; Nyman, T; Pacek, P; Saijonmaa, O | 1 |
| Emancipator, SN; Herman, WH; Rhoten, RL; Simonson, MS | 1 |
| Bembry, J; Kawai, N; Lenz, F; McCarron, RM; Spatz, M | 1 |
| Asano, M; Fujita, R; Hong, Y; Kawakami, Y; Matsuo, K; Miyauchi, T; Mizutani, M; Nakajima, T; Okuda, Y; Soma, M; Sone, H; Suzuki, H; Suzuki, S; Tsurumaru, K; Yamashita, K | 1 |
| Dlugosz, JA; Munk, S; Whiteside, CI; Zhou, X | 1 |
| Alexandrov, A; Goepel, M; Keffel, S; Michel, MC | 1 |
| Kugiyama, K; Matsumura, T; Miyamoto, E; Ogata, N; Oishi, Y; Yamamoto, H; Yasue, H | 1 |
| Apa, R; Ayala, G; de Feo, D; Lanzone, A; Mancuso, S; Miceli, F; Napolitano, M; Pierro, E | 1 |
| Cogolludo, A; Pérez-Vizcaíno, F; Tamargo, J | 1 |
| Fantus, IG; Glogowski, EA; Tsiani, E; Whiteside, C; Zhou, X | 1 |
| García-Sáinz, JA; Torres-Padilla, ME | 1 |
| Hayashi, K; Miyamoto, A | 1 |
| Kawamura, H; Kozawa, O; Matsui, N; Matsuno, H; Niwa, M; Otsuka, T; Tokuda, H; Uematsu, T | 1 |
| Chatterjee, A; Feener, EP; Jiang, ZY; King, GL; Myers, MG; White, MF; Zhou, QL | 1 |
| Fukuda, K; Kato, T; Kodama, H; Matsuzaki, J; Ogawa, S; Pan, J; Saito, M; Sano, M; Takahashi, T | 1 |
| Chiloeches, A; Clerk, A; Marais, R; Marshall, CJ; Paterson, HF; Sugden, PH | 1 |
| Arnheiter, H; Kos, L; Opdecamp, K; Pavan, WJ | 1 |
| Chen, P; Fisher, M; Hofman, FM; Kim, JA; Wang, JL; Zidovetzki, R | 1 |
| Hayasaki-Kajiwara, Y; Iwaki, K; Iwasaki, T; Kitano, Y; Nakajima, M; Naya, N; Shimamura, T | 1 |
| Aikawa, R; Komuro, I; Nagai, R; Saito, S; Shiojima, I; Yazaki, Y | 1 |
| Becker, K; Brodde, OE; Heinroth-Hoffmann, I; Osten, B; Pönicke, K | 1 |
| Palmer, TM; Stiles, GL | 1 |
| Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y | 1 |
| Flores, JA; Garmey, JC; Lahav, M; Veldhuis, JD | 1 |
| Henriques, MM; Rae, GA; Sampaio, AL | 1 |
| Gregersen, S; Hermansen, K; Thomsen, JL | 1 |
| Bell, D; McDermott, BJ | 2 |
| Bergman, M; Chentoufi, J; Gray, M; Honbo, NY; Karliner, JS; Piacentini, L | 1 |
| Jandrot-Perrus, M; Lepailleur-Enouf, D; Michel, JB; Philippe, M; Valdenaire, O | 1 |
| He, JQ; Kamp, TJ; Pi, Y; Walker, JW | 1 |
| Aikawa, R; Hayashi, D; Komuro, I; Kudoh, S; Mizukami, M; Nagai, R; Shibasaki, F; Shiojima, I; Toko, H; Yazaki, Y; Zhu, W; Zou, Y | 1 |
| Hatakeyama, D; Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T | 1 |
| Masgrau, R; Pardo, R; Picatoste, F; Sarri, E; Servitja, JM | 1 |
| Deng, XF; Rokosh, DG; Simpson, PC | 1 |
| Baba, A; Hashimoto, H; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
| Dai, J; Goldberg, JS; Nanus, DM; Navarro, D; Shen, R; Sumitomo, M | 1 |
| Apa, R; Garcia Pardo, M; Lanzone, A; Mancuso, S; Miceli, F; Minici, F; Navarra, P; Proto, C | 1 |
| Aizawa, T; Hashizume, K; Ikeo, S; Nakajima, K; Shigematsu, S; Yamauchi, K | 1 |
| Pan, JY; Wang, TH; Wu, B; Zhan, CY; Zhu, XN | 1 |
| Cook, DA; Nessim, MA; Vollrath, B; Wickman, G | 1 |
| Alcántara-Hernández, R; García-Sáinz, JA; Leyva-Illades, D | 1 |
| Clerk, A; Cole, SM; Pham, FH | 1 |
| Hong, SJ; Hwang, JH; Lai, YH; Wang, HZ; Wu, KY | 1 |
| Akimoto, T; Ando, Y; Asano, Y; Inoue, M; Ito, C; Kusano, E; Umino, T; Yanagiba, S | 1 |
| Blumberg, JB; Clément, SA; Kitta, K; Remeika, J; Suzuki, YJ | 1 |
| Matsuu, M; Naito, S; Nakashima, M; Nakayama, T; Sekine, I; Shimizu, S; Yamashita, S | 1 |
| Johnson, JA; Waller, J | 1 |
| Kozawa, O; Tokuda, H; Uematsu, T | 1 |
| Barton, PJ; Clerk, A; Harrison, JG; Kemp, TJ; Mullen, AJ; Sugden, PH | 1 |
| Aass, H; Andersen, GØ; Osnes, JB; Qvigstad, E; Schiander, I; Skomedal, T | 1 |
| Fauler, G; Köfeler, H; Leis, HJ; Raspotnig, G; Windischhofer, W; Zach, D | 1 |
| Johnson, JA | 1 |
| Allen, BG; Boivin, B | 1 |
| Heidkamp, MC; Martin, JL; Patel, N; Porter, MJ; Samarel, AM; Scully, BT | 1 |
| Gutkind, JS; Masgrau, R; Pardo, R; Picatoste, F; Sarri, E; Servitja, JM; von Eichel-Streiber, C | 1 |
| Kemnitz, KR; Pi, Y; Walker, JW; Wang, H; Zhang, D | 1 |
| Ito, H; Kato, K; Kozawa, O; Niwa, M; Oiso, Y; Tokuda, H | 1 |
| Bayer, AL; Byron, KL; Heidkamp, MC; Heller Brown, J; Howes, AL; Samarel, AM | 1 |
| Goto, K; Iemitsu, M; Irukayama-Tomobe, Y; Kasuya, Y; Miyauchi, T; Ogata, T; Sakai, S; Sudo, T; Takanashi, M; Yamaguchi, I | 1 |
| Khalil, RA; McNair, LL; Salamanca, DA | 1 |
| Miyamoto, A; Ohtani, M; Takase, S; Tetsuka, M; Wijayagunawardane, MP | 1 |
| Barman, SA; Johnson, JA | 1 |
| Molenaar, P; Russell, FD | 1 |
| Iwamoto, T; Katsuragi, T; Kita, S | 1 |
| Clerk, A; Markou, T; Sugden, PH; Yong, CS | 1 |
| Ilves, M; Kerkelä, R; Mäkinen, M; Orzechowski, HD; Paul, M; Pikkarainen, S; Ruskoaho, H; Tokola, H; Vuolteenaho, O | 1 |
| Delgado, DH; Miriuka, S; Ramzy, D; Rao, V; Ross, HJ; Sheshgiri, R; Tumiati, LC; Xu, N | 1 |
| Casas-González, P; García-Sáinz, JA | 1 |
| Dedman, JR; Kaetzel, MA; Li, B | 1 |
| Huh, SU; Jeong, SW; Kang, HW; Lee, JH; Moon, HJ; Park, JY; Soldatov, NM | 1 |
| Hanai, Y; Harada, A; Hosoi, T; Kozawa, O; Matsushima-Nishiwaki, R; Ohta, T; Takai, S; Tokuda, H | 1 |
| Ichiba, H; Kawabata, S; Kimura, S; Moroi, K; Nishiyama, M; Yajima, T | 1 |
| Avkiran, M; Cuello, F; Haworth, RS; Roberts, NA | 1 |
| Alsafi, A; Clerk, A; Cullingford, TE; Fuller, SJ; Giraldo, A; Markou, T; Sugden, PH; Weiss, SC | 1 |
| Eichhorst, J; Furkert, J; Kepura, F; Mousa, SS; Oksche, A; Plant, TD; Schaefer, M; Stein, C; Zöllner, C | 1 |
| Alcántara-Hernández, R; Casas-González, P; García-Sáinz, JA | 1 |
| Chen, DZ; Guo, J; Niu, XL; Pei, JM; Wang, WQ; Zhou, XD; Zhu, MZ; Zhu, XL; Zhu, XX | 1 |
| Adolfo García-Sáinz, J; Alcántara-Hernández, R | 1 |
| Bazowski, P; Czuba, Z; Dolezych, H; Hendryk, S; Jedrzejewska-Szypułka, H; Król, W | 1 |
| Chang, EI; Ikonomidis, JS; Jones, JA; Koval, C; Sheats, N; Spinale, FG; Stroud, RE; Zavadzkas, JA | 1 |
| Clerk, A; Fuller, SJ; Markou, T; Molkentin, JD; Paterson, HF; Sugden, PH; Tham, el L | 1 |
| Bers, DM; Chiamvimonvat, N; Myers, RE; Puglisi, JL; Samarel, AM; Timofeyev, V; Yuan, W | 1 |
| Chen, M; Dai, Y; Mehta, JL | 1 |
| Brizzolara, R; Cutolo, M; Montagna, P; Paolino, S; Pizzorni, C; Ruaro, B; Soldano, S; Sulli, A; Trombetta, AC | 1 |
1 review(s) available for tetradecanoylphorbol acetate and endothelin-1
| Article | Year |
|---|---|
Activation of the small GTP-binding protein Ras in the heart by hypertrophic agonists.
Topics: Adrenergic alpha-Agonists; Animals; Cardiomegaly; Endothelin-1; Heart; Humans; Monomeric GTP-Binding Proteins; Myocardium; Phenylephrine; Protein Binding; ras Proteins; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 2000 |
111 other study(ies) available for tetradecanoylphorbol acetate and endothelin-1
| Article | Year |
|---|---|
Mechanisms of endothelin-1 mRNA and peptides induction by TGF-beta and TPA in MDCK cells.
Topics: Animals; Cell Line; Dactinomycin; Dogs; Endothelin-1; Endothelins; Gene Expression Regulation; Kidney Tubules; Nucleic Acid Hybridization; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Human placental endothelin: expression of endothelin-1 mRNA by human placental fibroblasts in culture.
Topics: Blotting, Northern; Cells, Cultured; Endothelin-1; Endothelins; Epidermal Growth Factor; Female; Fibroblasts; Gene Expression; Gene Expression Regulation; Humans; Interleukin-1; Placenta; Pregnancy; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Trophoblasts | 1995 |
Iodine regulation of endothelin-1 gene expression in cultured porcine thyroid cells: possible involvement in autoregulation of the thyroid.
Topics: Animals; Blotting, Northern; Cells, Cultured; Cycloheximide; Endothelin-1; Endothelins; Gene Expression; Humans; Interleukin-1; Methimazole; Protein Kinase C; Protein Precursors; Recombinant Proteins; RNA, Messenger; Sodium Iodide; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transforming Growth Factor beta | 1993 |
Inhibitory effect of noradrenaline uptake inhibitors on contractions of rat aortic smooth muscle.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Aorta, Thoracic; Calcium; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitrogen Mustard Compounds; Norepinephrine; Potassium; Protriptyline; Rats; Rats, Sprague-Dawley; Sympathomimetics; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1996 |
Propofol regulation of calcium entry pathways in cultured A10 and rat aortic smooth muscle cells.
Topics: Anesthetics, Intravenous; Animals; Aorta; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Inositol Phosphates; Muscle, Smooth, Vascular; Nicardipine; Propofol; Rats; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Effective elimination of fibroblasts in cultures of melanocytes by lowering calcium concentration in TPA depleted medium following geneticin treatment.
Topics: Anti-Bacterial Agents; Calcium; Cell Separation; Cells, Cultured; Culture Media, Serum-Free; Endothelin-1; Fibroblast Growth Factor 2; Fibroblasts; Gentamicins; Humans; Infant, Newborn; Male; Melanocytes; Tetradecanoylphorbol Acetate | 1996 |
Autocrine effects of endothelin-1 on leukocyte-endothelial interaction: stimulation of endothelin B receptor subtype reduces endothelial adhesiveness via a nitric oxide-dependent mechanism.
Topics: Animals; Cats; Cell Adhesion; Cells, Cultured; Coronary Vessels; Endothelin-1; Histamine; Neutrophils; Nitric Oxide; P-Selectin; Receptor, Endothelin B; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Thrombin | 1996 |
Na(+)-K(+)-Cl- cotransport system in brain capillary endothelial cells: response to endothelin and hypoxia.
Topics: Animals; Brain; Carrier Proteins; Cells, Cultured; Chlorides; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Hypoxia, Brain; Indoles; Maleimides; Membrane Proteins; Potassium; Rats; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Genistein; Insulin; Isoflavones; Mitogen-Activated Protein Kinase 1; Myocardium; Polyenes; Polyunsaturated Alkamides; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Effect of growth factors on the expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in Rat-1 fibroblasts.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; Culture Media, Serum-Free; Cyclic AMP; DNA; Endothelin-1; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Fructose-Bisphosphatase; Growth Substances; Lysophospholipids; Phosphofructokinase-1; Phosphofructokinase-2; Rats; Recombinant Fusion Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1997 |
Effects of protein kinase C activation and inhibition on endothelin-1 release from human aortic and pulmonary artery endothelial cells: comparison with effects on bovine endothelin-1 and human prostaglandin I2 release.
Topics: Animals; Aorta; Cattle; Cells, Cultured; Diglycerides; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Protein Kinase C; Pulmonary Artery; Tetradecanoylphorbol Acetate | 1997 |
Functional properties of cultured endothelial cells derived from large microvessels of human brain.
Topics: Amiloride; Carrier Proteins; Cell Division; Cells, Cultured; Cerebrovascular Circulation; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate; Microcirculation; Ouabain; Potassium; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine | 1997 |
Expression of guanylyl cyclase-A/atrial natriuretic peptide receptor blocks the activation of protein kinase C in vascular smooth muscle cells. Role of cGMP and cGMP-dependent protein kinase.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Carcinogens; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Guanylate Cyclase; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Transfection | 1997 |
Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes.
Topics: Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Endothelin-1; Gene Expression Regulation; Genes, Reporter; Immediate-Early Proteins; Luciferases; Mitogen-Activated Protein Kinase 1; Myocardium; Phenylephrine; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Sarcomeres; Tetradecanoylphorbol Acetate | 1997 |
Activation of gene expression in cardiac myocytes by an antisense to MAP kinase phosphatase-1.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Cell Cycle Proteins; Cells, Cultured; Conserved Sequence; DNA, Antisense; Dual Specificity Phosphatase 1; Endothelin-1; Gene Expression Regulation; Genes, Immediate-Early; Genes, Reporter; Immediate-Early Proteins; Luciferases; Myocardium; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Regulation of phospholipases C and D in rat ventricular myocytes: stimulation by endothelin-1, bradykinin and phenylephrine.
Topics: Adrenergic alpha-Agonists; Animals; Bradykinin; Cells, Cultured; Endothelin-1; Heart Ventricles; Hydrolysis; Phenylephrine; Phosphatidylinositols; Phospholipase D; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Inhibition of inducible nitric oxide synthase expression by endothelin in rat glial cells prepared from the neonatal rat brain.
Topics: Animals; Animals, Newborn; Brain; Bucladesine; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Induction; Interleukin-1; Neuroglia; Nitric Oxide Synthase; Nitrites; Oligopeptides; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin B; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Myogenic constriction of human coronary arterioles.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Arterioles; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Cardiopulmonary Bypass; Child; Child, Preschool; Coronary Vessels; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Infant; Infant, Newborn; Middle Aged; Muscle Tonus; Muscle, Smooth, Vascular; Naphthalenes; Protein Kinase C; Regression Analysis; Tetradecanoylphorbol Acetate; Vascular Resistance; Vasoconstriction | 1997 |
Cross-talk between receptor-mediated phospholipase C-beta and D via protein kinase C as intracellular signal possibly leading to hypertrophy in serum-free cultured cardiomyocytes.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Culture Media, Serum-Free; Down-Regulation; Endothelin-1; Histones; Immunoblotting; Isoenzymes; Myocardium; Phenylephrine; Phospholipase C beta; Phospholipase D; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Activation of endothelin ETA receptors induces phosphorylation of alpha1b-adrenoreceptors in Rat-1 fibroblasts.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Cricetinae; Endothelin Receptor Antagonists; Endothelin-1; Fibroblasts; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Norepinephrine; Peptides, Cyclic; Phosphorylation; Rats; Receptor, Endothelin A; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Endothelin-1 inhibits endothelin-converting enzyme-1 expression in cultured rat pulmonary endothelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Carcinogens; Cell Line; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Ionomycin; Ionophores; Lung; Metalloendopeptidases; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Regulation of protein kinase C in the muscular layer of human placental stem villi vessels.
Topics: Blotting, Western; Cell Membrane; Cytosol; Endothelin-1; Enzyme Activation; Fluorides; Humans; Isoenzymes; Muscle, Smooth, Vascular; Phosphorylation; Placenta; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Regulation of endothelin-1 in human non-pigmented ciliary epithelial cells by tumor necrosis factor-alpha.
Topics: Cells, Cultured; Ciliary Body; Cycloheximide; Endothelin-1; Epithelial Cells; Fluorescent Antibody Technique; Glycopeptides; Humans; Protease Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Alterations in basal protein kinase C activity modulate renal afferent arteriolar myogenic reactivity.
Topics: 4-Aminopyridine; Alkaloids; Angiotensin II; Animals; Arterioles; Benzophenanthridines; Blood Pressure; Delayed Rectifier Potassium Channels; Endothelin-1; Enzyme Inhibitors; Hydronephrosis; Kidney; Male; Muscle, Smooth, Vascular; Perfusion; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Potassium Chloride; Protein Kinase C; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetradecanoylphorbol Acetate; Vasoconstriction | 1998 |
Oncostatin M regulates endothelin-1 production in human endothelial cells.
Topics: Benzoquinones; Cell Division; Cell Survival; Cells, Cultured; Drug Interactions; Endothelin-1; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Growth Inhibitors; Humans; Isoflavones; Lactams, Macrocyclic; Oncostatin M; Peptides; Protein Precursors; Protein-Tyrosine Kinases; Quinones; Rifabutin; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Umbilical Veins | 1998 |
Vascular and glomerular expression of endothelin-1 in normal human kidney.
Topics: Cells, Cultured; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Glomerular Mesangium; Humans; Kidney Glomerulus; Lupus Nephritis; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Protein Kinase C; Recombinant Proteins; Renal Circulation; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Transforming Growth Factor beta | 1998 |
Human brain capillary endothelium: modulation of K+ efflux and K+, Ca2+ uptake by endothelin.
Topics: Brain; Calcium; Calcium Channel Blockers; Capillaries; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-3; Endothelins; Endothelium, Vascular; Enzyme Activation; Humans; Indoles; Ion Transport; Maleimides; Potassium; Protein Kinase C; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Hypoxia and endothelin-1 induce VEGF production in human vascular smooth muscle cells.
Topics: Cell Hypoxia; Cells, Cultured; Cobalt; Endothelial Growth Factors; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Genistein; Growth Inhibitors; Humans; Lymphokines; Muscle, Smooth, Vascular; RNA, Messenger; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Endothelin-1-induced mesangial cell contraction involves activation of protein kinase C-alpha, -delta, and -epsilon.
Topics: Animals; Calcium; Cell Size; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Glomerular Mesangium; Immunoblotting; Ionomycin; Isoenzymes; Male; Microscopy, Confocal; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Stimulation of alpha1A-adrenoceptors in Rat-1 cells inhibits extracellular signal-regulated kinase by activating p38 mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cells, Cultured; Endothelin-1; Enzyme Activation; Fibroblasts; Isoenzymes; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Rats; Receptors, Adrenergic, alpha-1; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1998 |
The antibody specific for myristoylated alanine-rich C kinase substrate phosphorylated by protein kinase C: activation of protein kinase C in smooth muscle cells in human coronary arteries.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Coronary Vessels; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunoblotting; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Muscle, Smooth, Vascular; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Umbilical Veins | 1998 |
Endothelin-1: expression and role in human corpus luteum.
Topics: Adult; Azepines; Cells, Cultured; Chorionic Gonadotropin; Corpus Luteum; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Female; Humans; Oligopeptides; Progesterone; Receptor, Endothelin A; Tetradecanoylphorbol Acetate | 1998 |
Modulation of arterial Na+-K+-ATPase-induced [Ca2+]i reduction and relaxation by norepinephrine, ET-1, and PMA.
Topics: Animals; Calcium; Cytoplasm; Endothelin-1; Male; Mesenteric Arteries; Norepinephrine; Osmolar Concentration; Potassium Chloride; Sodium-Potassium-Exchanging ATPase; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 1999 |
High glucose alters the response of mesangial cell protein kinase C isoforms to endothelin-1.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Glomerular Mesangium; Glucose; Isoenzymes; Male; Osmolar Concentration; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1999 |
Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Cell Line; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Norepinephrine; Phentolamine; Piperazines; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-1; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Angiotensin II interacts with prostaglandin F2alpha and endothelin-1 as a local luteolytic factor in the bovine corpus luteum in vitro.
Topics: Abortifacient Agents, Nonsteroidal; Angiotensin II; Animals; Calcimycin; Cattle; Corpus Luteum; Dinoprost; Dose-Response Relationship, Drug; Endothelin-1; Female; In Vitro Techniques; Luteolytic Agents; Microdialysis; Pregnancy; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
Involvement of p42/p44 MAP kinase in endothelin-1-induced interleukin-6 synthesis in osteoblast-like cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; Tetradecanoylphorbol Acetate | 1999 |
Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells.
Topics: Animals; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; GTP-Binding Proteins; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Peptides, Cyclic; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphoserine; Protein Kinase C; Rats; Rats, Zucker; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes.
Topics: Angiotensin II; Animals; Antigens, CD; Autocrine Communication; Calcium; Carcinogens; Cardiomegaly; Cells, Cultured; Cytokine Receptor gp130; DNA-Binding Proteins; Endothelin-1; Gene Expression Regulation, Enzymologic; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Paracrine Communication; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase; STAT1 Transcription Factor; STAT3 Transcription Factor; Stress, Mechanical; Tetradecanoylphorbol Acetate; Trans-Activators; TYK2 Kinase | 1999 |
Regulation of Ras.GTP loading and Ras-Raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester. Activation of the extracellular signal-regulated kinase cascade by phorbol ester is mediated by Ras.
Topics: Animals; Cells, Cultured; Cyclic AMP; Down-Regulation; Endothelin-1; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Heart Ventricles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Pertussis Toxin; Phenylephrine; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Endothelin signalling in the development of neural crest-derived melanocytes.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-2; Endothelin-3; Endothelins; In Situ Hybridization; Melanocytes; Mice; Mice, Inbred C57BL; Neural Crest; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Endothelin-1 enhances plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-dependent pathway.
Topics: Brain; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Endothelium, Vascular; Humans; Plasminogen Activator Inhibitor 1; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Na(+)influx via Na(+)/H(+)exchange activates protein kinase C isozymes delta and epsilon in cultured neonatal rat cardiac myocytes.
Topics: Animals; Carcinogens; Cell Size; Cells, Cultured; Endothelin-1; Enzyme Activation; Guanidines; Heart Ventricles; Hydrogen-Ion Concentration; Ion Transport; Isoenzymes; Phenylephrine; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers; Sulfones; Tetradecanoylphorbol Acetate | 1999 |
Endothelin-1 induces expression of fetal genes through the interleukin-6 family of cytokines in cardiac myocytes.
Topics: Animals; Animals, Newborn; Antigens, CD; Atrial Natriuretic Factor; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclosporine; Cytokine Receptor gp130; Cytokines; Egtazic Acid; Endothelin-1; Gene Expression Regulation, Developmental; Growth Inhibitors; Heart; Interleukin-6; Ionomycin; Ionophores; Leukemia Inhibitory Factor; Lymphokines; Membrane Glycoproteins; Mutation; Myocardium; Myosin Heavy Chains; Natriuretic Peptide, Brain; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Gq/11-coupled receptors and protein synthesis in rat cardiomyocytes: role of Gi-proteins and protein kinase C-isozymes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Fatty Acids, Unsaturated; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Heart Ventricles; Hydrazines; Indoles; Inositol Phosphates; Isoenzymes; Maleimides; Norepinephrine; Pertussis Toxin; Phenylalanine; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tritium; Virulence Factors, Bordetella | 1999 |
Stimulation of A(2A) adenosine receptor phosphorylation by protein kinase C activation: evidence for regulation by multiple protein kinase C isoforms.
Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; CHO Cells; Consensus Sequence; Cricetinae; Cyclic AMP; Dogs; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Glioma; Indoles; Isoenzymes; Maleimides; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines; Triazoles; Tumor Cells, Cultured | 1999 |
Relationship between intracellular Ca2+ store and protein kinase C in agonist-induced contraction of hypertensive rat aortae.
Topics: Animals; Aorta; Calcium; Carcinogens; Endothelin-1; Enzyme Inhibitors; Indoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Phenylephrine; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma; Serotonin; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
Mechanisms underlying endothelin's inhibition of FSH-stimulated progesterone production by ovarian granulosa cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Endothelin-1; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Inositol Phosphates; Kinetics; Progesterone; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Role of endothelins on lymphocyte accumulation in allergic pleurisy.
Topics: Animals; Bosentan; CD4-Positive T-Lymphocytes; Chemotaxis, Leukocyte; Endothelin Receptor Antagonists; Endothelin-1; Humans; Interferon-gamma; Interleukin-4; Interleukin-5; Ionomycin; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Monensin; Oligopeptides; Ovalbumin; Peptides, Cyclic; Piperidines; Pleurisy; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Respiratory Hypersensitivity; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Endothelin-1 (ET-1)-potentiated insulin secretion: involvement of protein kinase C and the ET(A) receptor subtype.
Topics: Adrenergic Antagonists; Androstadienes; Animals; Cholinergic Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Naphthalenes; Peptide Fragments; Peptides, Cyclic; Phorbol Esters; Protein Kinase C; Receptor, Endothelin A; Receptors, Endothelin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Wortmannin | 2000 |
Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum.
Topics: Animals; Cattle; Cell Differentiation; Cell Survival; Chromans; Culture Media; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Fetal Blood; Glucose; Heart Ventricles; Hydrogen-Ion Concentration; Hypertrophy; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Male; Myocardium; Norepinephrine; Phenylalanine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Troglitazone | 2000 |
Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C.
Topics: Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; DNA; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Interleukin-1; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Myocardium; Phenanthridines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 2000 |
Thrombin induces endothelin expression in arterial smooth muscle cells.
Topics: Animals; Aorta; Arteries; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Gene Expression; Linear Models; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Protein Precursors; Proteins; Rats; Receptor, PAR-1; Receptors, Cytoplasmic and Nuclear; Receptors, Thrombin; RNA Polymerase II; RNA Stability; RNA, Messenger; Tetradecanoylphorbol Acetate; Thrombin; Transcription Factors; Transcription, Genetic | 2000 |
Endothelin-1 and photoreleased diacylglycerol increase L-type Ca2+ current by activation of protein kinase C in rat ventricular myocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carcinogens; Diglycerides; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Male; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Nifedipine; Phenanthridines; Photochemistry; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2000 |
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcimycin; Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Heart; Ionomycin; Kinetics; Models, Cardiovascular; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts: involvement of p38 mitogen-activated protein kinase.
Topics: Animals; Endothelial Growth Factors; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Imidazoles; Lymphokines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C; Pyridines; Pyrrolidinones; Receptor, Endothelin A; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Effects of oxidative stress on phospholipid signaling in rat cultured astrocytes and brain slices.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Chelating Agents; Egtazic Acid; Endothelin-1; Glutamic Acid; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Oxidative Stress; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phospholipids; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2000 |
Autonomous and growth factor-induced hypertrophy in cultured neonatal mouse cardiac myocytes. Comparison with rat.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Dinoprost; Endothelin-1; Fetus; Growth Inhibitors; Growth Substances; Heart; Hypertrophy; Interleukin-1; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Microscopy, Phase-Contrast; Models, Animal; Myocardium; Myosin Heavy Chains; Myosins; Norepinephrine; Phenotype; Phenylalanine; Protein Biosynthesis; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Triiodothyronine | 2000 |
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Bradykinin; Bucladesine; Cerebral Cortex; Chelating Agents; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Paxillin; Pertussis Toxin; Phosphoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Neutral endopeptidase promotes phorbol ester-induced apoptosis in prostate cancer cells by inhibiting neuropeptide-induced protein kinase C delta degradation.
Topics: Amino Acid Sequence; Apoptosis; Bombesin; Cell Division; CSK Tyrosine-Protein Kinase; Down-Regulation; Endothelin-1; Enzyme Activation; Growth Inhibitors; Humans; Isoenzymes; Male; Molecular Sequence Data; Neprilysin; Prostatic Neoplasms; Protein Kinase C; Protein Kinase C-delta; Protein-Tyrosine Kinases; src-Family Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Endothelins enhance prostaglandin (PGE(2) and PGF(2alpha)) biosynthesis and release by human luteal cells: evidence of a new paracrine/autocrine regulation of luteal function.
Topics: Antihypertensive Agents; Cells, Cultured; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-3; Female; Humans; Kinetics; Oligopeptides; Piperidines; Progesterone; Tetradecanoylphorbol Acetate | 2001 |
Differential effects of growth hormone and insulin-like growth factor I on human endothelial cell migration.
Topics: Cell Line; Cell Movement; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Epidermal Growth Factor; Human Growth Hormone; Humans; Indoles; Insulin-Like Growth Factor I; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Protein Kinase C; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
[The role of G protein, protein kinase C and Na(+)-H+ exchanger in endothelin-1-induced cardiomyocyte hypertrophic responses].
Topics: Animals; Animals, Newborn; Cardiomegaly; Cell Size; Cells, Cultured; Endothelin-1; GTP-Binding Proteins; Myocardium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1998 |
The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm.
Topics: Animals; Anti-Bacterial Agents; Bradykinin; Cells, Cultured; Cerebral Arteries; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Female; Gentamicins; Indoles; Isometric Contraction; Kanamycin; Male; Muscle, Smooth, Vascular; Neomycin; Peptides, Cyclic; Polyamines; Polyelectrolytes; Protein Kinase C; Pyrroles; Streptomycin; Tetradecanoylphorbol Acetate; Vasoconstriction; Vasospasm, Intracranial | 2001 |
Protein kinase C-alpha(1b)-adrenoceptor coimmunoprecipitation: effect of hormones and phorbol myristate acetate.
Topics: Adrenergic alpha-Agonists; Animals; Cell Line; Endothelin-1; Epidermal Growth Factor; Fibroblasts; Hormones; Immunoblotting; Isoenzymes; Lysophospholipids; Norepinephrine; Precipitin Tests; Protein Kinase C; Protein Kinase C-alpha; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate | 2001 |
Regulation of cardiac myocyte protein synthesis through phosphatidylinositol 3' kinase and protein kinase B.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Carcinogens; Carrier Proteins; Chromones; Electrophoresis, Gel, Two-Dimensional; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Flavonoids; Hypertrophy; Insulin; Intracellular Signaling Peptides and Proteins; Morpholines; Myocardium; Oxidative Stress; Peptide Initiation Factors; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Effects of drugs on cellular proliferation in cultured iris pigment epithelial cells and retinal pigment epithelial cells.
Topics: Animals; Bucladesine; Cell Division; Cells, Cultured; Dexamethasone; Endothelin-1; Iris; Pigment Epithelium of Eye; Swine; Tetradecanoylphorbol Acetate; Thymidine | 2001 |
Modulation of endothelin-1-induced cytosolic free calcium mobilization and mitogen-activated protein kinase activation by erythropoietin in vascular smooth muscle cells.
Topics: Animals; Biological Transport; Calcium; Cells, Cultured; Cytosol; Endothelin-1; Enzyme Activation; Erythropoietin; Extracellular Space; Humans; Ionomycin; Ionophores; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Osmolar Concentration; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2001 |
Endothelin-1 induces phosphorylation of GATA-4 transcription factor in the HL-1 atrial-muscle cell line.
Topics: Animals; Cell Line; DNA-Binding Proteins; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GATA4 Transcription Factor; Hydrogen Peroxide; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Tetradecanoylphorbol Acetate; Transcription Factors | 2001 |
Ets-1 upregulates matrix metalloproteinase-1 expression through extracellular matrix adhesion in vascular endothelial cells.
Topics: Animals; Cattle; Cell Adhesion; Cells, Cultured; Collagen Type I; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Integrins; Intercellular Adhesion Molecule-1; Matrix Metalloproteinase 1; Oligonucleotides, Antisense; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Up-Regulation | 2002 |
Transforming growth factor beta-1 attenuates endothelin-1-induced functions in neonatal cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Autoradiography; Blotting, Western; Densitometry; Endothelin-1; Fibroblast Growth Factor 1; Heart; Heart Rate; Isoenzymes; Myocardial Contraction; Myocardium; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Interleukin (IL)-17 enhances prostaglandin F(2 alpha)-stimulated IL-6 synthesis in osteoblasts.
Topics: Animals; Cells, Cultured; Data Interpretation, Statistical; Dinoprost; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Interleukin-17; Interleukin-6; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Tetradecanoylphorbol Acetate | 2002 |
Up-regulation of c-jun mRNA in cardiac myocytes requires the extracellular signal-regulated kinase cascade, but c-Jun N-terminal kinases are required for efficient up-regulation of c-Jun protein.
Topics: Animals; Endothelin-1; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Myocardium; Osmotic Pressure; Phenylephrine; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Alpha(1)-AR-induced positive inotropic response in heart is dependent on myosin light chain phosphorylation.
Topics: Animals; Azepines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cardiotonic Agents; Endothelin-1; Enzyme Inhibitors; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoproterenol; MAP Kinase Signaling System; Myocardial Contraction; Myosin Light Chains; Papillary Muscles; Phenylephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Receptors, Adrenergic, alpha-1; Receptors, Endothelin; rho-Associated Kinases; Tetradecanoylphorbol Acetate | 2002 |
Involvement of Rho and p38 MAPK in endothelin-1-induced expression of PGHS-2 mRNA in osteoblast-like cells.
Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Cell Line; Cholera Toxin; Cyclooxygenase 2; Dinoprostone; Endothelin-1; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; rho GTP-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2002 |
An epsilonPKC-selective inhibitor attenuates back phosphorylation of a low molecular weight protein in cardiac myocytes.
Topics: Animals; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Isoenzymes; Magnesium; Molecular Weight; Muscle Proteins; Myocytes, Cardiac; Peptides; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Tetradecanoylphorbol Acetate | 2003 |
Regulation of membrane-bound PKC in adult cardiac ventricular myocytes.
Topics: Age Factors; Animals; Carcinogens; Cell Membrane; Endothelin-1; Heart Ventricles; Male; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 2003 |
Isoenzyme-selective regulation of SERCA2 gene expression by protein kinase C in neonatal rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Calcium-Transporting ATPases; Carcinogens; Cells, Cultured; Down-Regulation; Endothelin-1; Gene Expression Regulation, Enzymologic; Heart Ventricles; Isoenzymes; Myocytes, Cardiac; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.
Topics: ADP-Ribosylation Factors; Animals; Astrocytes; Bacterial Proteins; Bacterial Toxins; Brefeldin A; Cells, Cultured; Chelating Agents; Cysteine; DNA; Dose-Response Relationship, Drug; Egtazic Acid; Endothelin-1; Glutamic Acid; Indoles; Maleimides; Phospholipase D; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; rho GTP-Binding Proteins; Stress Fibers; Sulfenic Acids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium.
Topics: Actin Cytoskeleton; Adenosine Triphosphatases; Adrenergic beta-Agonists; Alanine; Amino Acid Substitution; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; In Vitro Techniques; Isometric Contraction; Isoproterenol; Mice; Mice, Transgenic; Mutation; Myocardial Contraction; Myocardium; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Troponin I | 2003 |
Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.
Topics: Animals; Anthracenes; Blotting, Northern; Blotting, Western; Carbazoles; Endothelin-1; Enzyme Activators; Enzyme Inhibitors; Gene Expression Regulation; Heat-Shock Proteins; Immunoenzyme Techniques; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Chaperones; Naphthalenes; Neoplasm Proteins; Osteoblasts; p38 Mitogen-Activated Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase C epsilon-dependent activation of proline-rich tyrosine kinase 2 in neonatal rat ventricular myocytes.
Topics: Adenoviridae; Animals; Animals, Newborn; Blotting, Western; Cardiotonic Agents; Endothelin-1; Enzyme Activation; Heart Ventricles; Mutation; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Precipitin Tests; Proline; Protein Kinase C; Protein Kinase C-epsilon; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2003 |
Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway.
Topics: Animals; Animals, Newborn; Aorta; Cells, Cultured; Disease Models, Animal; Endothelin-1; Fenofibrate; Genes, fos; Genes, jun; Hypertrophy, Left Ventricular; JNK Mitogen-Activated Protein Kinases; Ligation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 2004 |
Endothelin-1 promotes Ca2+ antagonist-insensitive coronary smooth muscle contraction via activation of epsilon-protein kinase C.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Diltiazem; Disease Models, Animal; Drug Resistance; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Naphthalenes; Peptide Fragments; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Verapamil | 2004 |
Local interaction of prostaglandin F 2alpha with endothelin-1 and tumor necrosis factor-alpha on the release of progesterone and oxytocin in ovine corpora lutea in vivo: a possible implication for a luteolytic cascade.
Topics: Animals; Calcimycin; Corpus Luteum; Dinoprost; Endothelin-1; Female; Ionophores; Luteolysis; Microdialysis; Oxytocin; Progesterone; Sheep; Superovulation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Protein kinase C modulation of cyclic GMP in rat neonatal pulmonary vascular smooth muscle.
Topics: Animals; Animals, Newborn; Blotting, Western; Carbazoles; Cyclic GMP; Endothelin-1; Immunoblotting; Indoles; Isoenzymes; Lung; Maleimides; Muscle, Smooth, Vascular; Protein Kinase C; Pulmonary Circulation; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart.
Topics: Alkaloids; Amides; Androstadienes; Benzophenanthridines; Endothelin-1; Humans; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Myocardial Contraction; Myocardium; Myosin-Light-Chain Kinase; Phenanthridines; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Urotensins; Wortmannin | 2004 |
Effects of rosiglitazone and interactions with growth-regulating factors in ventricular cell hypertrophy.
Topics: Animals; Cell Survival; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Glucose; Heart Ventricles; Hypertrophy; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Male; Myocytes, Cardiac; Norepinephrine; Phenylalanine; Rats; Rats, Sprague-Dawley; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones | 2005 |
Endothelin-1 enhances the activity of Na+/Ca2+ exchanger type 1 in renal epithelial cells.
Topics: Animals; Benzophenanthridines; Calcium; Dogs; Endothelin-1; Epithelial Cells; Kidney; LLC-PK1 Cells; Mutation; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Sodium; Sodium-Calcium Exchanger; Swine; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes.
Topics: Animals; Animals, Newborn; Cell Culture Techniques; Cell Extracts; Cells, Cultured; Chromatography, Gel; Chromones; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Immunoblotting; Indoles; Maleimides; Morpholines; Myocytes, Cardiac; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C-delta; Pyrimidines; Rats; Rats, Sprague-Dawley; Solubility; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Inverse regulation of preproendothelin-1 and endothelin-converting enzyme-1beta genes in cardiac cells by mechanical load.
Topics: Animals; Aspartic Acid Endopeptidases; Cell Line; Cells, Cultured; Endothelial Cells; Endothelin-1; Endothelin-Converting Enzymes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; MAP Kinase Kinase 1; Metalloendopeptidases; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Receptor, Endothelin A; Stress, Mechanical; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway.
Topics: Alkaloids; Benzophenanthridines; Bosentan; Caveolin 1; Cell Membrane; Cells, Cultured; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Homeostasis; Isoenzymes; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenanthridines; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Transport; Saphenous Vein; Sulfonamides; Tetradecanoylphorbol Acetate | 2006 |
Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.
Topics: Adrenergic alpha-Agonists; Androstadienes; Animals; Antibodies; Cell Line; Cricetinae; Dose-Response Relationship, Drug; Endothelin-1; Epidermal Growth Factor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Norepinephrine; Phenylalanine; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Thiophenes; Tyrphostins; Wortmannin | 2006 |
Signaling pathways regulating murine cardiac CREB phosphorylation.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart; Isoenzymes; Isoproterenol; Mice; Molecular Sequence Data; Myocardial Reperfusion; Myocardium; Phosphorylation; Phosphoserine; Protein Kinase C-epsilon; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Activation of protein kinase C augments T-type Ca2+ channel activity without changing channel surface density.
Topics: Animals; Calcium; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Membrane Potentials; Membrane Transport Proteins; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Endothelin A; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Time Factors; Xenopus laevis | 2006 |
(-)-Epigallocatechin gallate suppresses endothelin-1-induced interleukin-6 synthesis in osteoblasts: inhibition of p44/p42 MAP kinase activation.
Topics: Animals; Anthracenes; Catechin; Cells, Cultured; Endothelin-1; Enzyme Activation; Flavonoids; Imidazoles; Interleukin-6; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyridines; Tetradecanoylphorbol Acetate | 2007 |
Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function.
Topics: Calcium; Cell Line; Electrophoresis, Polyacrylamide Gel; Endothelin-1; GTP-Binding Protein alpha Subunits; Humans; Peptide Fragments; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RGS Proteins; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Mice; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Troponin I | 2007 |
Glycogen synthase kinases 3alpha and 3beta in cardiac myocytes: regulation and consequences of their inhibition.
Topics: Animals; Benzazepines; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Indoles; Insulin; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2008 |
Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C.
Topics: Animals; Capsaicin; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Ganglia, Spinal; Humans; Inositol Phosphates; Male; Membrane Potentials; Mutation; Neurons; Patch-Clamp Techniques; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptor, Endothelin A; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Roles of c-Src in alpha1B-adrenoceptor phosphorylation and desensitization.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; beta-Adrenergic Receptor Kinases; Calcium; Chlorocebus aethiops; COS Cells; Cricetinae; Dose-Response Relationship, Drug; Endothelin-1; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; G-Protein-Coupled Receptor Kinase 5; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rats; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2008 |
[Inhibitory effects of rosiglitazone against endothelin-1-induced proliferation of rat cardiac myocytes: the role of PKC-c-fos pathway].
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Enlargement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Hypoglycemic Agents; Myocytes, Cardiac; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Rosiglitazone; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazolidinediones | 2008 |
Effect of inhibitors of mitogen-activated protein kinase kinase on alpha(1B)-adrenoceptor phosphorylation.
Topics: Androstadienes; Animals; Butadienes; Calcium Signaling; Cell Line; Cricetinae; Endothelin-1; Epidermal Growth Factor; Flavonoids; Genistein; Humans; Indoles; Lysophospholipids; Maleimides; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Norepinephrine; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Adrenergic, alpha-1; RNA, Small Interfering; Staurosporine; Tetradecanoylphorbol Acetate; Wortmannin | 2009 |
Increase in activity of neutrophils and proinflammatory mediators in rats following acute and prolonged focal cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Endothelin-1; Enzyme Activators; Interleukin-1beta; Male; Neutrophils; Radioimmunoassay; Rats; Rats, Wistar; Reperfusion; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 2010 |
Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Endothelin-1; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Genotype; Male; Mice; Mice, Inbred C57BL; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active.
Topics: Animals; Cells, Cultured; Endothelin-1; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 2011 |
Phorbol ester and endothelin-1 alter functional expression of Na+/Ca2+ exchange, K+, and Ca2+ currents in cultured neonatal rat myocytes.
Topics: Action Potentials; Animals; Animals, Newborn; Blotting, Western; Calcium Channels; Cell Size; Cells, Cultured; Electrophysiological Phenomena; Endothelin-1; In Vitro Techniques; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2011 |
Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear factor-kappa B activation.
Topics: Cells, Cultured; Endothelin-1; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; Liraglutide; NF-kappa B; Nitric Oxide Synthase Type III; Receptors, Glucagon; Tetradecanoylphorbol Acetate | 2013 |
Alternatively Activated (M2) Macrophage Phenotype Is Inducible by Endothelin-1 in Cultured Human Macrophages.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bosentan; Cell Differentiation; Cell Line; Chemokine CCL22; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation; Humans; Interleukin-10; Interleukin-4; Lectins, C-Type; Macrophage Activation; Macrophages; Mannose Receptor; Mannose-Binding Lectins; Matrix Metalloproteinase 9; Monocytes; Phenotype; Primary Cell Culture; Receptor, Endothelin A; Receptors, Cell Surface; Scavenger Receptors, Class A; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2016 |