tetradecanoylphorbol acetate has been researched along with dinoprostone in 637 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 147 (23.08) | 18.7374 |
| 1990's | 315 (49.45) | 18.2507 |
| 2000's | 134 (21.04) | 29.6817 |
| 2010's | 39 (6.12) | 24.3611 |
| 2020's | 2 (0.31) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Kotoyori, J; Kozawa, O; Miwa, M; Oiso, Y; Tokuda, H | 1 |
| McCaffrey, PG; Minowada, J; Oghiso, Y; Shibata, Y; Volkman, A | 1 |
| Conquer, JA; Cruz, TF; Kandel, RA | 1 |
| Davis, BB; Jacob, AK; Reznikoff, CA; Thomas, DJ; Zenser, TV | 1 |
| Decker, K; Dieter, P; Duyster, J; Hidaka, H | 1 |
| Nobunaga, M; Shiokawa, S; Yamamoto, M; Yasuda, M | 1 |
| Hinko, A; Soloff, MS | 2 |
| Dieter, P; Duyster, J; Fitzke, E; Schulze-Specking, A | 1 |
| Kawase, T; Orikasa, M; Suzuki, A | 2 |
| Fang, MA; Hahn, TJ; Kujubu, DA | 1 |
| Decker, K; Gaillard, T; Klein, H; Mülsch, A | 1 |
| Breyer, MD; Carter, CE; Jacobson, HR; Noland, TD | 1 |
| Gelderblom, D; Hough, S; Koch, HM; Muir, H | 1 |
| Fletcher, BS; Herschman, HR; Kujubu, DA; Perrin, DM | 1 |
| Anastassiou, ED; Balow, JP; Boumpas, DT; Paliogianni, F; Yamada, H | 1 |
| Olson, DM; Zakar, T | 2 |
| Goad, DL; Meurer, EA; Petrou, CP; Tashjian, AH; Voelkel, EF | 1 |
| Kozawa, O; Oiso, Y; Tokuda, H | 1 |
| Hayashi, J; Liu, PS; Sun, L; Wen, M | 1 |
| Decker, K; Dieter, P; Duyster, J; Grewe, M; Henninger, H; Schulze-Specking, A | 1 |
| Abramsky, O; Boneh, A; Brenner, T; Shohami, E; Weidenfeld, J | 1 |
| Edwin, SS; Mitchell, MD | 1 |
| Aizu, E; Kato, R; Yamamoto, S | 1 |
| Catalano, DE; Fogarasi, M; Szabo, G; Verma, BK | 1 |
| Matic, M; Simon, SR | 1 |
| MacLeod, EA; Olson, DM; Zakar, T | 1 |
| Børglum, JD; Richelsen, B; Sørensen, SS | 1 |
| Hoffman, T; Pierce, JH; Puri, J | 2 |
| Bechtel, DH; Belury, MA; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Maldve, RE; Slaga, TJ | 1 |
| Berglindh, T; Nygård, G | 2 |
| Jiang, H; Kato, R; Yamamoto, S | 3 |
| Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW | 1 |
| Goin, M; Jimenez de Asua, L | 1 |
| Herschman, HR; Kujubu, DA | 1 |
| Sahai, A; Sandler, RS; Shayman, JA; Tannen, RL; Xu, G | 1 |
| Evans, CH; Georgescu, HI; Hulkower, KI | 1 |
| Dziak, R; Hagel-Bradway, S; Tatakis, DN | 1 |
| Fujie, K; Handa, H; Mino, M; Nishihira, J; Sakamoto, W | 1 |
| Kawakubo, A; Kozawa, O; Miwa, M; Oiso, Y; Takatsuki, K; Tokuda, H; Yoneda, M | 1 |
| Bagash, JM; Coogan, M; Lozano, Y; Young, ME; Young, MR | 1 |
| Bismuth, G; Debré, P; Feuillard, J; Gouy, H; Körner, M; Lee, LM | 1 |
| Michelson, S; Paya, CV; Virelizier, JL | 1 |
| Bensussan, A; Bihoreau, C; Corvaïa, N; Degos, L; Enjalbert, A; Heurtier, A; Kordon, C | 1 |
| Becker, S; Devlin, RB; Koren, HS; Madden, MC; Newman, SL | 1 |
| Fabbro, D; Huwiler, A; Pfeilschifter, J | 1 |
| Sung, SS; Walters, JA | 1 |
| Lerner, UH; Ransjö, M | 1 |
| Fujie, K; Handa, H; Sakamoto, W | 1 |
| Hori, K; Ito, S; Miyakawa, A; Mochizuki-Oda, N; Negishi, M; Ozaki, K | 1 |
| Prior, G; Thierauch, KH | 1 |
| Ceuppens, JL; Vandenberghe, P | 1 |
| Agwu, DE; McCall, CE; McPhail, LC | 1 |
| Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Grenfell, S; Ray, K; Rollins, P; Sadler, H; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Khademazad, M; Loessberg, P; Muallem, S; Whisenant, N; Zhang, BX | 1 |
| Davis, BB; Jacob, AK; Thomas, DJ; Zenser, TV | 1 |
| Freyaldenhoven, AM; Gutierrez, GE; Katz, MS; Lifschitz, MD | 1 |
| Baxter, CS; Leikauf, GD; Smith, JS; Wey, HE | 1 |
| Fujie, K; Mino, M; Morita, I; Murota, S; Nishihira, J; Sakamoto, W | 1 |
| Hosang, M; Pfeilschifter, J | 1 |
| Decker, K; Schulze-Specking, A; Weinhold, L | 1 |
| Annat, J; Derrepas, P; Dutartre, P; Pascal, M | 1 |
| Astruc, ME; Crastes de Paulet, A; Lahoua, Z; Michel, F; Vial, H | 1 |
| Beil, W; Bersimbaev, R; Sewing, KF | 1 |
| Kaever, V; Resch, K | 1 |
| Ballou, LR; Barker, SC; Candela, M | 1 |
| Nanes, MS; Rubin, JE; Titus, L | 1 |
| Kaldy, P; Schmitt-Verhulst, AM | 1 |
| Kizaki, H; Suzuki, K; Tadakuma, T | 1 |
| Evans, CH; Hulkower, KI | 1 |
| Souhrada, JF; Souhrada, M | 1 |
| Cameron, GS; Fischer, SM; Lee, ML; Patrick, KE | 1 |
| Bechtel, D; Belury, MA; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Slaga, TJ | 1 |
| Fürstenberger, G; Kaszkin, M; Kinzel, V | 1 |
| Duniec, ZM; Eling, TE; Nettesheim, P | 1 |
| Abrahamsen, TG; Carter, CS; Hoffman, T; Jessop, JJ; Lee, YL; Lizzio, EF; Puri, J; Taplits, M; Tripathi, AK | 1 |
| Ammar, A; Bertoli, AM; Cibert, C; Georgoulias, V; Jasmin, C; Tsilivakos, V | 1 |
| Goppelt-Strübe, M; Hartmann, A; Hass, R; Köhler, L; Lonnemann, G; Männel, D; Resch, K; Topley, N | 1 |
| Decker, K; Gyufko, K; Tran-Thi, TA | 1 |
| Yokota, K | 1 |
| Fischer, SM; Slaga, TJ; Vo, TK | 1 |
| Belury, MA; Cumberland, AG; Fischer, SM; Locniskar, M; Patrick, KE | 1 |
| Branch, DW; Daynes, RA; Dudley, DJ; Lundin-Schiller, S; Mitchell, MD; Romero, RJ | 1 |
| Tai, HH; Tian, ZG; Xun, CQ | 1 |
| Dieter, P; Fitzke, E | 1 |
| Davis, LS; Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Belizario, JE; Dinarello, CA | 1 |
| Isakson, PC; Judd, AM; MacLeod, RM; Spangelo, BL | 1 |
| Ensor, CM; Tai, HH; Xun, CQ | 1 |
| Cottam, GL; Matsunaga, A; Miller, BC | 1 |
| Bentz, BG; Billiar, TR; Curran, RD; Lysz, TW; Machiedo, GW; Simmons, RL | 1 |
| Kaever, V; Pfannkuche, HJ; Resch, K; Wessel, K | 2 |
| Emilsson, A; Sundler, R; Wijkander, J | 1 |
| Iaizzo, PA; Olsen, RA; Powis, G; Seewald, MJ; Sehgal, I | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Emoto, T; Hattori, Y; Hiraiwa, M; Kasai, K; Kuroda, H; Shimoda, S; Yamazaki, A | 1 |
| Davis, BB; Duniec, ZM; Eling, TE; Wong, YH; Zenser, TV | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 1 |
| DeWitt, DL; Goppelt-Struebe, M; Hass, R; Koehler, L; Resch, K | 1 |
| Coyne, DW; Mordhorst, M; Morrison, AR | 1 |
| Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Ozeki, T; Tamura, T; Tsurufuji, S; Watanabe, M | 1 |
| Baldari, CT; Donati, D; Macchia, G; Massone, A; Parente, L; Telford, JL | 1 |
| Seechurn, P; Thody, AJ | 1 |
| Bauer, J; Cosman, D; Dower, SK; Jonas, U; Lioubin, PJ; Sims, JE; Slack, J; Spriggs, MK | 1 |
| Lin, MC; Wu, YY | 1 |
| Teitelbaum, I | 1 |
| Dunn, MJ; Simonson, MS | 1 |
| Hurme, M | 1 |
| Pfeilschifter, J | 1 |
| McCaffrey, PG; Oghiso, Y; Sato, H; Shibata, Y | 1 |
| Beubler, E; Hinterleitner, T; Horina, G | 1 |
| Hurme, M; Ronni, T; Serkkola, E; Silvennoinen, O | 1 |
| Bankey, P; Carlson, A; Cerra, F; Ortiz, M; Singh, R | 1 |
| Classen, M; Schepp, W; Schneider, J; Schusdziarra, V; Tatge, C | 1 |
| Fertel, RH; Gabbe, SG; Iams, JD; Kniss, DA; Mershon, J; Sonek, J; Su, HC; Waxman, M | 1 |
| Baeuerle, PA; Haas, JG; Riethmüller, G; Ziegler-Heitbrock, HW | 1 |
| Friedmann, PS; Matthews, JN; Wren, FE | 1 |
| Campbell, IK; Hamilton, JA; Piccoli, DS | 1 |
| Hayaishi, O; Ito, S; Negishi, M | 1 |
| Kamei, T; Moriguchi, H; Nakamura, Y; Ogura, T; Ozaki, T; Yasuoka, S | 1 |
| Brown, BL; Dobson, PR; Martin, TJ; Michelangeli, VP; Moseley, JM; Russell, RG; Short, AD | 1 |
| Goppelt-Strübe, M; Möller, A | 1 |
| Farnsworth, LJ; Fine, A; Goldstein, RH; Polgar, P; Poliks, C | 1 |
| Fujiki, H; Lazzaro, M; Levine, L; Tashjian, AH | 1 |
| Aussel, C; Fehlmann, M | 1 |
| Brown, MR; Chew, CS | 1 |
| Douglas, JG; Dubyak, G; Welsh, C | 1 |
| Fürstenberger, G; Gschwendt, M; Herald, CL; Kittstein, W; Marks, F; Pettit, GR; Rogers, M; Rose-John, S | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Baumberger, C; Dayer, JM; Demczuk, S; Mach, B | 1 |
| Atwell, MM; Hanson, PJ | 1 |
| Conklin, BR; Felder, CC; Ma, AL | 1 |
| Soll, AH; Toomey, M | 1 |
| Alonso, M; Cárdenas, L; Carrera, AC; de Landázuri, MO; Sánchez-Madrid, F; Tugores, A | 1 |
| Leung, PC; Wang, J; Yuen, BH | 1 |
| Seidler, U; Sewing, KF | 1 |
| Lee, V; Leung, PC; Wang, J | 1 |
| Leung, PC; Wang, J | 1 |
| Davis, BB; Wong, YH; Zenser, TV | 1 |
| Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Tamura, T; Tsurufuji, S; Watanabe, M | 1 |
| Kaever, V; Pfannkuche, HJ; Resch, K | 1 |
| Albright, E; Field, FJ; Mathur, SN | 1 |
| Festa, F; Pfeilschifter, J; Thüring, B | 1 |
| Kanzaki, T; Morisaki, N; Saito, Y; Yoshida, S | 1 |
| Evans, CH; Georgescu, HI; Kuhns, DB; Watanabe, S | 1 |
| Harris, RC | 1 |
| Cosowsky, L; Raufman, JP | 1 |
| Bachelet, M; Béréziat, G; Kadiri, C; Masliah, J; Vargaftig, BB | 1 |
| Insel, PA; Slivka, SR; Weiss, BA | 1 |
| Bandara, G; Evans, CH; Georgescu, HI; Lin, CW; Mendelow, D | 1 |
| Bützow, R; Jalkanen, J; Koistinen, R; Ranta, T; Ritvos, O; Seppälä, M; Suikkari, AM | 1 |
| Biddulph, DM; Dozier, MM | 1 |
| Duell, EA; Elder, JT; Esmann, J; Fisher, GJ; Gupta, AK; Nickoloff, BJ; Talwar, HS; Voorhees, JJ | 1 |
| Kamps, JA; Kuiper, J; Van Berkel, TJ | 1 |
| Duggin, GG; Horvath, JS; Lazzaro, VA; Tiller, DJ; Walker, RJ | 1 |
| Aboolian, A; Nord, EP; Vander Molen, M | 1 |
| Bertrand, W; Coyne, DW; Mordhorst, M; Morrison, AR | 1 |
| Cunha-Neto, E; Rizzo, LV | 1 |
| Coffey, JW; Fiedler-Nagy, C; Georgiadis, A; Hope, WC; Welton, AF; Wittreich, BH | 1 |
| Welsh, MJ | 1 |
| Hoshi, T; Shimada, T | 1 |
| Beckner, SK; Darfler, FJ; Lin, MC | 1 |
| Deli, E; Kiss, Z; Kuo, JF | 1 |
| Fukumoto, Y; Hamamori, Y; Takai, Y; Tsuda, T; Yamashita, T | 1 |
| García-Sáinz, JA; Juárez-Ayala, J | 1 |
| Bouton, MM; Dartois, E | 2 |
| Sobel, DO | 1 |
| Alonso, M; De Landázuri, MO; López-Botet, M; López-Rivas, A; Rincón, M; Silva, A; Tugores, A | 1 |
| Fredholm, BB; Kvanta, A; Nordstedt, C | 1 |
| Bismuth, G; Debre, P; Gouy, H; le Gouvello, S; Theodorou, I | 1 |
| Hayaishi, O; Hayashi, H; Ito, S; Negishi, M; Sugama, K; Yokohama, H | 1 |
| Bützow, R; Lehto, VP; Ranta, T; Ritvos, O; Seppälä, M | 1 |
| Fujiki, H; Levine, L; Ohuchi, K; Suganuma, M; Sugimura, T; Tsurufuji, S; Watanabe, M; Yoshizawa, K | 1 |
| Enna, SJ; Karbon, EW; Shenolikar, S | 1 |
| Hayaishi, O; Hayashi, H; Ito, S; Negishi, M; Tanaka, T; Yokohama, H | 1 |
| Bernard, A; Bismuth, G; Debré, P; Gouy, H; Le Gouvello, S; Theodorou, I | 1 |
| Bourne, HR; Chang, FH; Hochhaus, G; Richards, ML; Sadée, W; Yu, VC | 1 |
| Fürstenberger, G; Gross, M; Marks, F | 1 |
| Inoue, H; Koshihara, Y; Mori, T; Shibata, S | 1 |
| Hastings, LA; Lewbart, ML; Pashko, LL; Schwartz, AG | 1 |
| Dale, MM; Penfield, A | 1 |
| Levine, SD; Schlondorff, D | 1 |
| Novogrodsky, A; Patya, M; Stenzel, KH | 1 |
| Beckner, SK; Farrar, WL | 2 |
| Conn, PM; Costa, ME; Katz, KH; Ojeda, SR; Urbanski, HF | 1 |
| Cruchaud, A; Dayer, JM; Roux-Lombard, P | 1 |
| Götz, D; Knepel, W | 1 |
| Hansen, JA; June, CH; Ledbetter, JA; Martin, PJ; Parsons, M; Rabinovitch, PS | 1 |
| Hidaka, H; Kawakami, K; Ohmura, T; Onoue, K; Yamamoto, Y | 1 |
| DiMartino, MJ; Hanna, N; Johnson, WJ | 1 |
| Jelinek, DF; Lipsky, PE; Simkin, NJ | 1 |
| Harada, S; Nakashima, H; Yamamoto, N | 1 |
| Gerhards, J; Mehler, EL | 1 |
| Deli, E; Girard, PR; Kiss, Z; Kuo, JF; Pettit, GR | 1 |
| Amiel, C; Friedlander, G | 1 |
| Johnson, WJ; Sung, CP | 1 |
| Chouaib, S; Dupont, B; Robb, RJ; Welte, K | 1 |
| Daly, JW; Hollingsworth, EB | 1 |
| Cleveland, JL; Evans, SW; Farrar, WL; Rapp, UR | 1 |
| Crutchley, DJ; Smariga, PE | 1 |
| Lanz, R; Szelenyi, I | 1 |
| Danon, A; Davis, BB; Thomasson, DL; Zenser, TV | 1 |
| Glimcher, LH; Ohara, J; Paul, WE; Poljak, A; Polla, BS | 1 |
| Espe, U; Fürstenberger, G; Kaszkin, M; Kinzel, V; Marks, F | 1 |
| Fischer, SM; Fürstenberger, G; Marks, F; Slaga, TJ | 1 |
| Faberman, J; Fürstenberger, G; Ganss, M; Marks, F; Richter, H; Rogers, M | 1 |
| Christensen, SB; Fujiki, H; Hirasawa, N; Ohuchi, K; Sugawara, T; Sugimura, T; Tsurufuji, S; Watanabe, M | 1 |
| Benninghoff, B; Dröge, W; Häcker-Shahin, B; Kriegbaum, H | 1 |
| Akimoto, K; Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S; Takaoka, T | 1 |
| Benjamin, CW; Gorman, RR; Tarpley, WG | 1 |
| Fujiki, H; Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugimura, T; Takahashi, C; Tsurufuji, S; Watanabe, M | 1 |
| Demers, LM; Veldhuis, JD | 1 |
| Johnsen, SA; Papadogiannakis, N | 1 |
| Shimizu, Y; Takasu, N; Yamada, T | 1 |
| Craven, PA; DeRubertis, FR; Patterson, MC | 2 |
| Burch, RM | 1 |
| Bonventre, JV; Kremer, SG; Kudlow, JE; Margolis, BL; Skorecki, KL | 1 |
| Béliard, R; Bocquet, J; Bouakka, M; Jouis, V; Langris, M; Legendre, P; Loyau, G | 1 |
| Davis, BB; Thomasson, DL; Zenser, TV | 1 |
| Maclouf, J; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Fujiki, H; Hirasawa, N; Ohuchi, K; Ozeki, T; Tsurufuji, S; Watanabe, M | 1 |
| Dubyak, GR; Moore, JJ; Moore, RM; Vander Kooy, D | 1 |
| Maclouf, J; Pelé, JP; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| Blackham, A; Griffiths, RJ; Li, S; Wood, BE | 1 |
| Glaser, KB; Jacobs, RS; Mayer, AM | 1 |
| Axelrod, J; Burch, RM; Ma, AL | 1 |
| Lytton, FD; Mitchell, MD | 1 |
| Decker, K; Gyufko, K; Häussinger, D; Tran-Thi, TA | 1 |
| Feyen, JH; Kream, BE; Petersen, DN | 1 |
| Berchuck, A; Casey, ML; MacDonald, PC; Milewich, L | 1 |
| Fischer, SM; Reiners, JJ | 1 |
| Ferber, E; Flesch, I | 1 |
| Krug, E; Tashjian, AH | 1 |
| Sato, S; Shimizu, Y; Takasu, N; Yamada, T | 1 |
| Barrett, ML; Edwards, MC; Evans, FJ; Gordon, D | 1 |
| Cornwell, DG; Milo, GE; Morisaki, N; Tomei, LD | 1 |
| Dinarello, CA; Kelley, V; Reddish, M; Rosenwasser, LJ; Strom, TB; Williams, JM | 1 |
| Bartalini, M; Boraschi, D; Censini, S; Tagliabue, A | 1 |
| Kanoh, H; Kondoh, H; Sato, Y | 1 |
| Fligiel, SE; Perone, P; Varani, J | 1 |
| Duque, RE; Kunkel, SL | 1 |
| Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP; Siegel, MI | 1 |
| Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Peters, SP | 1 |
| Brinckerhoff, CE; Harris, ED | 1 |
| Murray, AW; Solanki, V | 1 |
| Brinckerhoff, CE; Nagel, JE | 1 |
| Shupnik, MA; Tashjian, AH | 1 |
| Itoh, T; Tomoda, A; Yagawa, K | 1 |
| Iyer, N; King, L; Krebs, C; Kucera, LS; Waite, BM | 1 |
| Chedid, L; Deriaud, E; Leclerc, C; Morin, A | 1 |
| Butler-Gralla, E; Herschman, HR; Taplitz, S | 1 |
| Beaudry, GA; Daniel, LW; King, L; Waite, M | 1 |
| Aehringhaus, U; Brune, K; Peskar, BA | 1 |
| Barnes, WT; Cobb, MA; Hsueh, W; Pachman, LM | 1 |
| Marcelo, CL; Roseeuw, DI; Voorhees, JJ | 1 |
| Blumberg, PM; Jaken, S; Shupnik, MA; Tashjian, AH | 1 |
| Delescluse, C; Fischer, SM; Fürstenberger, G; Marks, F; Richter, H | 1 |
| Berry, DL; Bertsch, S; Fürstenberger, G; Marks, F; Richter, H | 1 |
| Levine, L | 1 |
| Ishii, M; Kato, R; Nakadate, T; Yamamoto, S | 2 |
| Takenaga, K | 1 |
| Honma, Y; Hozumi, M; Kasukabe, T | 1 |
| Brune, K; Lanz, R | 1 |
| Imre, K; Jacobson, PB; Kuchera, SL; Metz, A; Schächtele, C; Schrier, DJ | 1 |
| Eling, TE; Hamasaki, Y | 1 |
| Cole, OF; Elder, MG; Seki, H; Sullivan, MH | 1 |
| Brockman, DE; Myatt, L; Slater, DM; Xue, S | 1 |
| Bertram, P; Scutt, A; Zeschnigk, M | 1 |
| Li, X; Nemenoff, RA; Schrier, RW; Zarinetchi, F | 1 |
| Curtis, JF; Eling, TE; Glasgow, WC; Hui, R; Shears, SB; Sumner, MT | 1 |
| Gohda, E; Iwao, M; Kataoka, H; Matsunaga, T; Takebe, T; Wu, YL; Yamamoto, I | 1 |
| Iitaka, M; Ishii, J; Kitahama, S | 1 |
| Florio, C; Heisler, S; Martin, JG; Styhler, A | 1 |
| Cadman, ED; Lee, CM; Witte, DG | 1 |
| DiBattista, JA; Jolicoeur, FC; Martel-Pelletier, J; Morin, N; Pelletier, JP | 1 |
| Bascands, JL; Bompart, G; Girolami, JP; Pecher, C; Rakotoarivony, J; Tack, JL | 1 |
| Abu-Lawi, KI; Sultzer, BM | 1 |
| Alpert, E; Wang, W | 1 |
| Chik, CL; Ho, AK; Karpinski, E; Kovacs, CS; Li, B | 1 |
| Dewald, B; Fey, MF; Meier, RW; Niklaus, G; Tobler, A | 1 |
| Brennand, JE; Calder, AA; Greer, IA; Kelly, RW; Leask, R | 1 |
| Matsumoto, K; Nakamura, T; Okazaki, H | 1 |
| DiBattista, JA; Iwata, K; Martel-Pelletier, J; Pelletier, JP; Zafarullah, M | 1 |
| Fortier, MA; Kim, JJ | 1 |
| Daphna-Iken, D; Morrison, AR; Srivastava, SK; Tetsuka, T | 1 |
| Lepak, NM; Serrero, G | 1 |
| Caflisch, CR; George, T; Good, DW | 1 |
| Bonneau, MJ; Doualla-Bell, F; Fortier, MA; Labrie, F | 1 |
| Araki, M; Inaba, H; Mizuguchi, T | 1 |
| Lloret, S; Moreno, JJ | 1 |
| Jisaka, M; Takeuchi, J; Takinami, K; Yokota, K | 1 |
| Grimes, RW; Hammond, JM; Samaras, SE | 1 |
| Gordon, JA; Spector, AA; Warnock, LJ | 1 |
| Amon, U; Subramanian, N; von Stebut, E; Wolff, HH | 1 |
| Boumpas, DT; Kincaid, RL; Paliogianni, F | 1 |
| Bascands, JL; Girolami, JP; Pecher, C | 1 |
| Burdick, MD; Crofford, LJ; Kunkel, SL; Peters-Golden, M; Strieter, RM; Wilborn, J | 1 |
| Hernández-Hernández, A; Llanillo, M; Rodríguez, MC; Sánchez-Yagüe, J | 1 |
| Chen, XS; Funk, CD; Griffis, G; Kurre, U | 1 |
| Fujie, K; Gotoh, K; Handa, H; Inoue, N; Kaga, M; Nishihira, J; Sakamoto, W; Suzuki, S | 1 |
| Ichikawa, A; Katoh, H; Negishi, M; Sugimoto, Y; Watabe, A | 1 |
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| Bomalaski, JS; Knight, DA; Misso, NL; Petrovic, N; Thompson, PJ | 1 |
| Avellar, MC; Calixto, JB; Medeiros, R; Otuki, MF | 1 |
| Ho, SY; Ho, YS; Lai, CS; Liu, HI; Pan, MH; Tai, C; Wang, YJ | 1 |
| Fischer, MJ; Reeh, PW | 1 |
| Abayasekara, DR; Cheng, Z; Flint, AP; Marshall, E; Sheldrick, EL; Wathes, DC | 1 |
| Babad, JM; Garay, M; Liebel, FT; Southall, MD; Sur, R | 1 |
| Ahn, BH; Kwon, TK; Lee, YH; Min, do S; Park, MH | 1 |
| Giner, RM; Hernández, V; Máñez, S; Recio, MC; Ríos, JL | 1 |
| Kupeli, E; Tosun, A; Yesilada, E | 1 |
| Bezouglaia, O; Camargo, PM; Nervina, JM; Pham, L; Tetradis, S | 1 |
| Akkol, EK; Güvenç, A; Yeşilada, E | 1 |
| Choi, SY; Eum, WS; Jang, SH; Ju, SM; Kwon, HJ; Lee, JA; Park, J; Song, HY; Won, MH; Yoo, KY | 1 |
| Choi, HS; Kim, BY; Kim, JW; Kim, KH; Lee, HG; Park, OJ; Park, SN; Shim, JH; Shin, JI; Yoon, DY | 1 |
| Castro, R; Lamas, J; Leiro, J; Morais, P; Orallo, F; Sanmartín, ML | 1 |
| Chapdelaine, P; Fortier, MA; Krishnaswamy, N; Tremblay, JP | 1 |
| Deck, LM; Gonzales, AM; Hunsaker, LA; Orlando, RA; Vander Jagt, DL | 1 |
| Bae, ON; Chung, JH; Chung, SM; Kim, EJ; Lee, JY; Lee, SM; Lim, KM; Noh, JY | 1 |
| Katiyar, SK; Meeran, SM; Punathil, T; Vaid, M | 1 |
| Baek, DY; Kim, DH; Kim, JK; Kim, YH; Lim, H; Shin, HK | 1 |
| Fehrenbacher, JC; Hargreaves, KM; Henry, MA; Locke, EE; Sun, XX | 1 |
| Arroyo, M; de la Puerta, R; Fernandez-Arche, A; Garcia, MD; Saenz, MT | 1 |
| Kim, DH; Kim, JK; Lim, H; Shin, EK; Shin, HK | 1 |
| Choi, JH; Han, EH; Im, JH; Jeong, HG; Kim, HG; Kim, JY; Woo, ER | 1 |
| Fjaeraa, C; Karlsson, S; Nånberg, E; Wijkander, J | 1 |
| Choe, J; Eom, S; Ha, KS; Hahn, JH; Jeoung, D; Kim, K; Kim, Y; Kim, YM; Lee, H; Lee, YS; Ro, JY | 1 |
| Lau, GT; Leung, LK; Ye, L | 1 |
| Jang, TJ; Jeon, KH; Jung, KH | 1 |
| Leung, LK; Yi Lau, GT | 1 |
| Hur, S; Kim, TY; Lee, YS; Yang, JH; Yoo, H | 1 |
| Huang, H; Lau, GT; Leung, LK; Lin, SM | 1 |
| Abel, E; Fischer, SM; Mikulec, C; Pavone, A; Rundhaug, J; Surh, I | 1 |
| Cheng, YW; Hsu, YY; Huang, CC; Shyur, LF; Yang, SD | 1 |
| Cho, HJ; Kim, J; Kim, JS; Kim, SG; Lee, YM; Park, JH; Ponnuraj, SP | 1 |
| Chand, AL; Clyne, CD; Herridge, KA; Howard, TL; Simpson, ER | 1 |
| Chowdhury, AA; Ishikawa, T; Jisaka, M; Nagaya, T; Nishimura, K; Rahman, MS; Shono, F; Yokota, K | 1 |
| Che, CT; Ip, SP; Lin, ZX; Mao, QQ; Xian, YF | 1 |
| Fabregat, I; Martín-Sanz, P; Sancho, P | 1 |
| Ahn, EH; Cho, SW; Choi, SY; Eum, WS; Han, KH; Jeong, HJ; Kang, HW; Kang, TC; Kim, DW; Kim, J; Kim, YN; Kwon, SW; Lee, MJ; Park, J; Shin, MJ; Sohn, EJ; Won, MH | 1 |
| Katiyar, SK; Singh, T | 1 |
| Armstrong, VJ; Galea, GL; Javaheri, B; Lanyon, LE; Moustafa, A; Price, JS; Saxon, LK; Sunters, A; Zaman, G | 1 |
| Bohrman, JS; Fischer, SM; Gleason, GL; Hardin, LG; Slaga, TJ | 1 |
| Koyama, N; Paulo, M; Salvador, M; Stocco, B; Toledo, K; Torqueti Toloi, MR | 1 |
| Choi, JH; Chung, YC; Han, EH; Jang, WS; Jeong, HG; Khanal, T; Kim, HG; Park, BH; Tran, TP | 1 |
| Chen, JN; Ip, SP; Lai, XP; Lin, ZX; Su, ZR; Xian, YF; Xu, XY | 1 |
| Han, YS; Hwang, JK; Kim, MS | 1 |
| Enoki, T; Kato, I; Ohnogi, H; Sagawa, H; Takashima, F; Tominaga, T | 1 |
| Guo, CM; Kasaraneni, N; Myatt, L; Sun, K | 1 |
| Fabiani, R; Fuccelli, R; Morozzi, G; Rosignoli, P; Servili, M | 1 |
| Cho, HJ; Kang, YH; Lee, HN; Lee, KW; Lim, DY; Park, JH | 1 |
| Chang, JE; Jin, QR; Lee, WJ; Maeng, HJ; Shim, WS | 1 |
| Aggarwal, V; Monga, J; Nongalleima, K; Sharma, M; Suthar, SK | 1 |
| Dai, GL; Feng, CT; Ju, WZ; Ma, ST; Miao, CG; Song, Y; Yu, H; Zhang, XL; Zhou, GL | 1 |
| Cao, W; Cao, WX; Feng, ZQ; Guan, X; Guo, JW; Han, QJ; Li, B; Li, YY; Qin, J; Wang, Y; Zhang, HJ; Zhang, MJ; Zhou, J | 1 |
| Abidi, L; Avesi, L; Faizi, S; Farooq, AD; Mirza, T; Naqvi, S; Siddiqui, F | 1 |
| Akram, M; Bae, ON; Kim, CY; Kim, ES; Kim, KA; Lee, JS; Syed, AS | 1 |
| Hara, T; Kogo, H; Nakamura, K; Naraba, H; Tachikawa, E; Tamura, K; Yoshie, M | 1 |
| Gu, Y; Huang, LY; Li, G; Wang, C | 1 |
| Akram, M; Bae, ON; Baek, SH; Chang, SY; Kim, H; Kim, KA; Noh, D; Shin, I | 1 |
| Chao, J; Chen, LL; Liu, JF; Zhang, HJ | 1 |
| Aida, E; Hara, S; Kamei, D; Kuwata, H; Nakatani, Y; Ochiai, T; Sasaki, Y | 1 |
| Chelariu-Raicu, A; Dong, X; Jeschke, U; Kuhn, C; Peng, L; von Schönfeldt, V; Ye, Y | 1 |
3 review(s) available for tetradecanoylphorbol acetate and dinoprostone
| Article | Year |
|---|---|
Immunologic aspects of preterm labor.
Topics: Amnion; Arachidonic Acid; Chorioamnionitis; Cytokines; Dinoprostone; Female; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Lipopolysaccharides; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Infectious; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uterus | 1991 |
Effects of tumor promoters on arachidonic acid metabolism by cells in culture.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cell Line; Cycloheximide; Dinoprostone; Growth Substances; Humans; Indomethacin; Lipid Metabolism; Male; Peptide Hydrolases; Phorbols; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate; Time Factors; Vitamin A; Vitamin E | 1982 |
The regulation of cyclooxygenase-1 and -2 in knockout cells and cyclooxygenase and fever in knockout mice.
Topics: Animals; Arachidonic Acid; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Dinoprostone; Fever; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Knockout; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Substrate Specificity; Tetradecanoylphorbol Acetate | 2000 |
1 trial(s) available for tetradecanoylphorbol acetate and dinoprostone
| Article | Year |
|---|---|
Capsaicin-evoked iCGRP release from human dental pulp: a model system for the study of peripheral neuropeptide secretion in normal healthy tissue.
Topics: Adolescent; Adult; Biological Assay; Biopsy; Calcitonin Gene-Related Peptide; Capsaicin; Dental Pulp; Dinoprostone; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Models, Biological; Models, Neurological; Nociceptors; Pain; Receptors, Opioid, mu; Sensory Receptor Cells; Sensory System Agents; Tetradecanoylphorbol Acetate; TRPV Cation Channels; Young Adult | 2009 |
633 other study(ies) available for tetradecanoylphorbol acetate and dinoprostone
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Inositol Phosphates; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Second Messenger Systems; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Regulation of phospholipase A2 activation and arachidonic acid metabolism in an interleukin-3-dependent macrophage-like cell line.
Topics: Animals; Arachidonic Acids; Biological Transport; Bone Marrow; Bone Marrow Cells; Calcimycin; Calcium; Cell Fractionation; Cells, Cultured; Dinoprostone; Eicosanoids; Enzyme Activation; Hydrogen-Ion Concentration; Interleukin-3; Leukotriene B4; Macrophages; Mice; Mice, Inbred CBA; Phospholipases A; Phospholipases A2; Protein Kinase C; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Interleukin 1 and phorbol 12-myristate 13-acetate induce collagenase and PGE2 production through a PKC-independent mechanism in chondrocytes.
Topics: Alkaloids; Animals; Arachidonic Acid; Cartilage, Articular; Cattle; Cell Compartmentation; Cells, Cultured; Dinoprostone; Enzyme Induction; Interleukin-1; Microbial Collagenase; Phospholipases A; Phospholipases A2; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Altered regulation of arachidonic acid metabolism by SV40 immortalized human urothelial cells.
Topics: Arachidonic Acid; Aspirin; Bradykinin; Calcimycin; Cell Line, Transformed; Dinoprostone; Diterpenes; Microsomes; Prostaglandin-Endoperoxide Synthases; Simian virus 40; Terpenes; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
Proteinkinase C beta-isoform triggers the formation of prostanoids and superoxide in liver macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Isoenzymes; Liver; Macrophages; Male; Prostaglandins; Protein Kinase C; Rats; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Intracellular signal transduction in proliferation of synovial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cell Division; Cells, Cultured; Cyclic AMP; Cytokines; Dinoprostone; Humans; Interleukin-1; Isoquinolines; Piperazines; Protein Kinase C; Signal Transduction; Synovial Membrane; Tetradecanoylphorbol Acetate; Theophylline | 1992 |
Characterization of oxytocin receptors in rabbit amnion involved in the production of prostaglandin E2.
Topics: Amnion; Animals; Arginine Vasopressin; Binding, Competitive; Calcimycin; Cell Membrane; Cells, Cultured; Decidua; Dinoprostone; Female; Kinetics; Oxytocin; Pregnancy; Rabbits; Receptors, Angiotensin; Receptors, Oxytocin; Receptors, Vasopressin; Tetradecanoylphorbol Acetate; Uterus | 1992 |
Protein kinase C involved in zymosan-induced release of arachidonic acid and superoxide but not in calcium ionophore-elicited arachidonic acid release or formation of prostaglandin E2 from added arachidonate.
Topics: Alkaloids; Animals; Arachidonic Acids; Blotting, Western; Calcimycin; Carbazoles; Cells, Cultured; Dinoprostone; Indole Alkaloids; Kupffer Cells; Male; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Phorbol ester-like action of staurosporine on the cAMP response to prostaglandin E2 in two macrophage-like cell lines at distinct differentiation stages.
Topics: Alkaloids; Animals; Cell Differentiation; Cell Line; Culture Media; Cyclic AMP; Dinoprostone; Macrophages; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells.
Topics: Animals; Bone Neoplasms; Calcium; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Immediate-Early Proteins; Inositol Phosphates; Mitosis; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinases; Radioimmunoassay; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors; Tritium; Tumor Cells, Cultured; Zinc Fingers | 1992 |
Regulation by prostaglandin E2 of cytokine-elicited nitric oxide synthesis in rat liver macrophages.
Topics: Animals; Bucladesine; Cyclic AMP; Cytokines; Dinoprostone; Interleukin-1; Kupffer Cells; Lipopolysaccharides; Liver; Macrophages; Male; Nitric Oxide; Rats; Rats, Wistar; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
PGE2 regulates cAMP production in cultured rabbit CCD cells: evidence for dual inhibitory mechanisms.
Topics: Alkaloids; Animals; Arginine Vasopressin; Cells, Cultured; Cyclic AMP; Dinoprostone; Kidney Cortex; Kidney Tubules, Collecting; Pertussis Toxin; Prostaglandins; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Protein kinase C modulates parathyroid hormone- but not prostaglandin E2-mediated stimulation of cyclic AMP production via the inhibitory guanine nucleotide binding protein in UMR-106 osteosarcoma cells.
Topics: Adenylate Cyclase Toxin; Animals; Cyclic AMP; Dinoprostone; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Osteosarcoma; Parathyroid Hormone; Pertussis Toxin; Phosphorylation; Precipitin Tests; Protein Kinase C; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Dinoprostone; DNA; Exons; Genetic Vectors; Humans; Introns; Mice; Microsomes; Molecular Sequence Data; Peroxidases; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1992 |
Prostaglandin E2 and other cyclic AMP-elevating agents modulate IL-2 and IL-2R alpha gene expression at multiple levels.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Blotting, Northern; Cholera Toxin; Cyclic AMP; Dinoprostone; Gene Expression; Humans; Interleukin-2; Isoquinolines; Lymphocyte Activation; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; RNA; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Prostaglandin synthesis regulation in human amnion tissue: involvement of protein kinase C and dependence on ribonucleic acid and protein synthesis.
Topics: Amnion; Cycloheximide; Dactinomycin; Dinoprostone; Enzyme Activation; Female; Humans; In Vitro Techniques; Pregnancy; Protein Biosynthesis; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate | 1992 |
Protein phosphatase inhibitors and bone resorption: inhibition by okadaic acid and biphasic actions of calyculin-A.
Topics: Animals; Animals, Newborn; Autoradiography; Bone and Bones; Bone Resorption; Calcitriol; Calcium; Cyclic AMP; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Kinetics; Marine Toxins; Mice; Mice, Inbred Strains; Okadaic Acid; Organ Culture Techniques; Oxazoles; Parathyroid Hormone; Peptide Fragments; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorus Radioisotopes; Protein Biosynthesis; Protein Phosphatase 1; RNA; Teriparatide; Tetradecanoylphorbol Acetate | 1992 |
Protein kinase C activation amplifies prostaglandin F2 alpha-induced prostaglandin E2 synthesis in osteoblast-like cells.
Topics: Animals; Arachidonic Acids; Cell Line; Dinoprost; Dinoprostone; Enzyme Activation; Kinetics; Melitten; Mice; Osteoblasts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of prostaglandin production in rat thymic epithelial cells by protein kinase C mediated activation of phospholipase A2.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Enzyme Activation; Epithelium; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thymus Gland | 1992 |
Prostaglandin D2 and E2 syntheses in rat Kupffer cells are antagonistically regulated by lipopolysaccharide and phorbol ester.
Topics: Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Kupffer Cells; Lipopolysaccharides; Male; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1992 |
Glucocorticoid regulation of eicosanoid production by glial cells under basal and stimulated conditions.
Topics: Animals; Dexamethasone; Dinoprostone; Glucocorticoids; Lipopolysaccharides; Neuroglia; Phospholipases A; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1992 |
The regulation of prostaglandin biosynthesis in cells derived from human gestational tissues: effects of fetal calf serum.
Topics: Amnion; Arachidonic Acid; Chorion; Culture Media; Decidua; Dinoprostone; Epidermal Growth Factor; Extraembryonic Membranes; Female; Humans; In Vitro Techniques; Interleukin-1; Ionomycin; Pregnancy; Tetradecanoylphorbol Acetate | 1992 |
Anthralin, a non-TPA type tumor promoter, synergistically enhances phorbol ester-caused prostaglandin E2 release from primary cultured mouse epidermal cells.
Topics: Animals; Anthralin; Arachidonic Acid; Carcinogens; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Drug Synergism; Epidermis; Mice; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1992 |
Induction of transforming growth factor-beta and prostaglandin E2 production by ethanol in human monocytes.
Topics: Cell Line; Cell Survival; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Ethanol; Humans; Indomethacin; Interferon-gamma; Kinetics; Lipopolysaccharides; Monocytes; Recombinant Proteins; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1992 |
Effects of gamma interferon on release of tumor necrosis factor alpha from lipopolysaccharide-tolerant human monocyte-derived macrophages.
Topics: Cells, Cultured; Dinoprostone; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Monocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1992 |
Glucocorticoid stimulation of amnion cell prostaglandin synthesis: suppression by protein kinase C inhibitors and independence of phorbol ester-sensitive protein kinase C.
Topics: Alkaloids; Amnion; Cells, Cultured; Dexamethasone; Dinoprostone; Humans; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Biosynthetic capacity and regulatory aspects of prostaglandin E2 formation in adipocytes.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Chromatography, High Pressure Liquid; Dinoprostone; Epinephrine; Glycerol; Insulin; Lipolysis; Male; Phospholipases A; Phospholipases A2; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1992 |
Transduction of a signal for arachidonic acid metabolism by untriggered CSF-1 receptor induces an opposite effect to that induced by CSF-1 receptor and its ligand: separate regulation of phospholipase A2 and cyclooxygenase by CSF-1 receptor/CSF-1.
Topics: Animals; Annexins; Arachidonic Acid; Calcium-Binding Proteins; Cinnamates; Dinoprostone; Hematopoietic Stem Cells; Ionomycin; Macrophage Colony-Stimulating Factor; Membrane Lipids; Mice; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Recombinant Proteins; Signal Transduction; Sulfides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Differential effects of dietary linoleic acid on mouse skin-tumor promotion and mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dinoprostone; Fatty Acids; Female; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Sequential incorporation of 3H- and 14C-arachidonic acid during 24 h in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Compartmentation; Colon; Culture Techniques; Dinoprostone; Intestinal Mucosa; Lipid Metabolism; Male; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases A; Rabbits; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Staurosporine, a potent protein kinase C inhibitor, augments phorbol ester-caused ornithine decarboxylase induction in mouse epidermis.
Topics: Administration, Topical; Alkaloids; Animals; Dinoprostone; Drug Synergism; Enzyme Induction; Epidermis; Female; Indomethacin; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella | 1992 |
Stimulation of protein kinase C (PKC) activity in resting Swiss 3T3 cells by prostaglandin F2 alpha.
Topics: 3T3 Cells; Alprostadil; Animals; Cell Division; Diglycerides; Dinoprost; Dinoprostone; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Mice; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.
Topics: 3T3 Cells; Animals; Blotting, Northern; Colforsin; Dexamethasone; Dinoprostone; Mice; Mitogens; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Signal transduction events whereby PGF2 alpha inhibits the ammoniagenic response to acute acidosis.
Topics: Acidosis; Acute Disease; Alanine; Amiloride; Ammonia; Animals; Calcium Channel Blockers; Cell Line; Dinoprostone; Egtazic Acid; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Evidence that responses of articular chondrocytes to interleukin-1 and basic fibroblast growth factor are not mediated by protein kinase C.
Topics: Alkaloids; Animals; Cartilage, Articular; Cells, Cultured; Dinoprostone; Enzyme Activation; Fibroblast Growth Factor 2; Gelatinases; Interleukin-1; Isoenzymes; Kinetics; Pepsin A; Phosphoproteins; Phosphorylation; Protein Kinase C; Rabbits; Recombinant Proteins; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Prostaglandin-induced changes in calcium uptake and cAMP production in osteoblast-like cells: role of protein kinase C.
Topics: Calcium; Cell Line; Cyclic AMP; Dinoprostone; Humans; Osteoblasts; Osteosarcoma; Phorbol Esters; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Vitamin E inhibits PGE2 and O2- production in rat peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Fura-2; Macrophages; Male; Peritoneum; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Vitamin E | 1991 |
Effects of hypergravity on proliferation and differentiation of osteoblast-like cells.
Topics: Alkaline Phosphatase; Animals; Cell Differentiation; Cell Division; Cell Line; Cyclic AMP; Cyclic GMP; Dinoprostone; DNA; Gravitation; Osteoblasts; Protein Kinase C; Radioimmunoassay; Somatomedins; Tetradecanoylphorbol Acetate | 1991 |
Regulation of protein kinase A activation and prostaglandin E2-stimulated migration of Lewis lung carcinoma clones.
Topics: Animals; Cell Movement; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Lung Neoplasms; Mice; Neoplasm Metastasis; Phosphoproteins; Protein Kinase C; Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
NF-kappa B activation by tumor necrosis factor alpha in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca(2+)-regulated kinases.
Topics: Calcium; Cell Line; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphoma; NF-kappa B; Nigericin; Oligonucleotide Probes; Protein Kinase C; Protein Kinases; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Modulation of T-cell activation through protein kinase C- or A-dependent signalling pathways synergistically increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins.
Topics: Antigens, CD; CD4 Antigens; Cell Line; Colforsin; Cyclic AMP; Cytomegalovirus; Dinoprostone; HIV Long Terminal Repeat; Humans; Kinetics; Lymphocyte Activation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1991 |
Activation of the CD3/T cell receptor (TcR) complex or of protein kinase C potentiate adenylyl cyclase stimulation in a tumoral T cell line: involvement of two distinct intracellular pathways.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Calcium; CD3 Complex; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Humans; In Vitro Techniques; Inositol Phosphates; Leukemia, T-Cell; Muromonab-CD3; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Modulation of human alveolar macrophage properties by ozone exposure in vitro.
Topics: Adult; Cryptococcus neoformans; Dinoprostone; Female; Humans; Interleukin-1; Interleukin-6; Macrophage Colony-Stimulating Factor; Macrophages, Alveolar; Male; Ozone; Protein Biosynthesis; Receptors, Fc; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Possible regulatory functions of protein kinase C-alpha and -epsilon isoenzymes in rat renal mesangial cells. Stimulation of prostaglandin synthesis and feedback inhibition of angiotensin II-stimulated phosphoinositide hydrolysis.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Glomerular Mesangium; Hydrolysis; Immunoenzyme Techniques; Isoenzymes; Kinetics; Molecular Sequence Data; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Increased cyclic AMP levels enhance IL-1 alpha and IL-1 beta mRNA expression and protein production in human myelomonocytic cell lines and monocytes.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Hematopoietic Stem Cells; Humans; Interleukin-1; Lipopolysaccharides; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Effects of phorbol esters and pertussis toxin on calcitonin-stimulated accumulation of cyclic AMP in neonatal mouse calvarial bones.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bone Resorption; Calcitonin; Cyclic AMP; Dinoprostone; GTP-Binding Proteins; Indomethacin; Mice; Osteoclasts; Parathyroid Hormone; Peptide Fragments; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Inhibition of prostaglandin E2 and superoxide anion production in rat peritoneal macrophages by the calcium antagonists nifedipine and nisoldipine.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Fura-2; In Vitro Techniques; Macrophages; Male; Nifedipine; Nisoldipine; Peritoneal Cavity; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Characterization of prostaglandin E2-induced Ca2+ mobilization in single bovine adrenal chromaffin cells by digital image microscopy.
Topics: Adrenal Medulla; Animals; Calcium; Calcium Channel Blockers; Cattle; Chromaffin System; Dinoprostone; Fluorescent Dyes; Fura-2; Hexamethonium; Hexamethonium Compounds; Histamine; Kinetics; Lanthanum; Microscopy, Fluorescence; Nicardipine; Nicotine; Nicotinic Antagonists; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Modulation of platelet activation by prostaglandin E2 mimics.
Topics: Blood Platelets; Calcium; Cyclic AMP; Dinoprost; Dinoprostone; Humans; Iloprost; Platelet Activation; Receptors, Epoprostenol; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1991 |
Immobilized anti-CD5 together with prolonged activation of protein kinase C induce interleukin 2-dependent T cell growth: evidence for signal transduction through CD5.
Topics: Adult; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; CD5 Antigens; Cyclosporins; Dinoprostone; Enzyme Activation; Female; Humans; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Monocytes; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Transferrin; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Regulation of phospholipase D-induced hydrolysis of choline-containing phosphoglycerides by cyclic AMP in human neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; Cyclic AMP; Dinoprostone; Humans; Hydrolysis; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1991 |
Characterization of the 3',5'-cyclic adenosine monophosphate-mediated regulation of IL2 production by T cells and Jurkat cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Cell Line; Cholera Toxin; Cyclic AMP; Dinoprostone; Humans; Interleukin-2; Leukemia; Phosphatidylinositols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Modification of biological responses to interleukin-1 by agents that perturb signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Flow Cytometry; Interleukin-1; Interleukin-2; Lymphocyte Activation; Mice; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Regulation of Na-K-2Cl cotransport in osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Kinetics; Osteoblasts; Osteosarcoma; Ouabain; Parathyroid Hormone; Potassium; Rubidium; Second Messenger Systems; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1991 |
Regulation of prostaglandin H synthase activity in dog urothelial cells.
Topics: Alkaloids; Animals; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dinoprostone; Dogs; Prostaglandin-Endoperoxide Synthases; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
Protein kinase C differentially modulates PTH- and PGE2-sensitive adenylate cyclase in osteoblast-like cells.
Topics: Adenylyl Cyclases; Animals; Dinoprostone; GTP-Binding Proteins; Osmolar Concentration; Osteoblasts; Parathyroid Hormone; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1992 |
JB6 murine epidermal cell lines sensitive and resistant to 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced transformation exhibit differential arachidonic acid metabolism in response to TPA and the calcium ionophore A23187.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Chromatography, High Pressure Liquid; Dinoprostone; Drug Resistance; Epoprostenol; Mice; Mice, Inbred BALB C; Radioimmunoassay; Skin; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of PGE2 production in macrophages from vitamin E-treated rats.
Topics: Animals; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dinoprostone; Macrophages; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vitamin E | 1991 |
Effects of homo- and heterodimeric isoforms of PDGF on signalling events in rat renal mesangial cells.
Topics: Animals; Cell Division; Cells, Cultured; Dinoprostone; Glomerular Mesangium; Inositol Phosphates; Kinetics; Neutralization Tests; Pertussis Toxin; Phosphatidylcholines; Platelet-Derived Growth Factor; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Signal transduction in endotoxin-stimulated synthesis of TNF-alpha and prostaglandin E2 by rat Kupffer cells. Role of extracellular calcium ions and protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cells, Cultured; Dinoprostone; Egtazic Acid; Endotoxins; Interferon-gamma; Isoquinolines; Kinetics; Kupffer Cells; Lipopolysaccharides; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Recombinant Proteins; Salmonella; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Implications of prostaglandin E2 synthesis and phospholipase C activation in potentiation of T-cell proliferation by LF 1695.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Dinoprostone; Inositol Phosphates; Lymphocyte Activation; Mice; Piperidines; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Oxysterol activation of arachidonic acid release and prostaglandin E2 biosynthesis in NRK 49F cells is partially dependent on protein kinase C activity [corrected].
Topics: Animals; Arachidonic Acid; Blood; Calcitriol; Calcium; Cell Line; Dinoprostone; Hydroxycholesterols; Ionomycin; Ketocholesterols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Signal transduction pathway in gastric mucous cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbachol; Cell Membrane; Cholera Toxin; Colforsin; Cytosol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Phosphatidylserines; Protein Kinase C; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Eicosanoid synthesis in murine macrophages can be shifted from prostaglandins to leukotrienes but not vice versa by specific inhibitors of cyclooxygenase or 5'-lipoxygenase activity.
Topics: Animals; Calcimycin; Calcium; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Indoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Macrophages; Mice; Mice, Inbred DBA; Prostaglandins; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Sphingosine synergistically stimulates tumor necrosis factor alpha-induced prostaglandin E2 production in human fibroblasts.
Topics: Cell Line; Dinoprostone; Drug Synergism; Fibroblasts; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Proteins; Sialoglycoproteins; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Effects of prostaglandin E2 and F2 alpha on cytoplasmic pH in a clonal osteoblast-like cell line, MOB 3-4.
Topics: Animals; Calcium; Cell Line; Clone Cells; Cyclic AMP; Dinoprost; Dinoprostone; DNA Replication; Hydrogen-Ion Concentration; Inositol Phosphates; Mice; Osteoblasts; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Prostaglandin E2 induction of monoblastic differentiation utilizes both cAMP and non-cAMP dependent signalling systems.
Topics: Calcitriol; Calcium; Cell Differentiation; Cell Line; Cyclic AMP; Dinoprostone; Humans; Isoenzymes; Monocytes; Protein Kinase C; Protein Kinases; Receptor, Anaphylatoxin C5a; Receptors, Complement; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation | 1991 |
Cyclic AMP synergy with Ca2+ for production of IFN-gamma by a cytolytic T cell clone is post-transcriptional.
Topics: Animals; Blotting, Northern; Calcium; Cell Line; Cyclic AMP; Cyclosporins; Dinoprostone; Drug Synergism; Gene Expression; In Vitro Techniques; Interferon-gamma; Ionomycin; Lymphocyte Activation; Mice; Protein Kinase C; Receptors, Antigen, T-Cell; RNA Processing, Post-Transcriptional; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Modulation of thymocyte apoptosis by isoproterenol and prostaglandin E2.
Topics: Animals; Cell Survival; Cyclic AMP; Dinoprostone; DNA Damage; In Vitro Techniques; Isoproterenol; L-Lactate Dehydrogenase; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymus Gland | 1991 |
Protein phosphorylation and metalloproteinase synthesis by lapine articular chondrocytes.
Topics: Animals; Blotting, Western; Calcium; Calmodulin; Cartilage, Articular; Cells, Cultured; Cyclic AMP; Dinoprostone; Electrophoresis, Gel, Two-Dimensional; Interleukin-1; Metalloendopeptidases; Microbial Collagenase; Phosphorylation; Protein Kinase C; Proteins; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Respiratory epithelium-dependent inhibition of protein kinase C of airway smooth muscle cells.
Topics: Animals; Dinoprostone; Epithelium; Guinea Pigs; Indomethacin; Isometric Contraction; Membrane Potentials; Muscle, Smooth; Protein Kinase C; Tetradecanoylphorbol Acetate; Trachea; Verapamil | 1991 |
4 Beta- and 4 alpha-12-O-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cycloheximide; Dactinomycin; Dinoprostone; Down-Regulation; Epidermis; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effects of type of dietary fat on phorbol ester-elicited tumor promotion and other events in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Corn Oil; Dinoprostone; Female; Linoleic Acid; Linoleic Acids; Mice; Mice, Inbred DBA; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Interference of xanthate compounds with phorbol ester TPA-induced changes of phospholipid metabolism: inhibition of prostaglandin production.
Topics: Arachidonic Acid; Arachidonic Acids; Bridged-Ring Compounds; Diglycerides; Dinoprostone; HeLa Cells; Humans; Norbornanes; Phospholipids; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 1991 |
Stimulation of prostaglandin H synthase mRNA levels and prostaglandin biosynthesis by phorbol ester: mediation by protein kinase C.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Enzyme Activation; Epithelial Cells; Epithelium; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Rats; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Trachea | 1991 |
Absence of modulation of monokine production via endogenous cyclooxygenase or 5-lipoxygenase metabolites: MK-886 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2- dimethylpropanoic acid), indomethacin, or arachidonate fail to alter immunor
Topics: Analysis of Variance; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Concanavalin A; Dinoprostone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Indoles; Indomethacin; Interleukin-1; Leukotriene Antagonists; Lipopolysaccharides; Monocytes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1991 |
Endogenous activation of prostaglandin synthesis in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Fractionation; Cell Membrane; Cells, Cultured; Colon; Cycloheximide; Cytochalasin B; Dinoprostone; In Vitro Techniques; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Tetradecanoylphorbol Acetate | 1991 |
Biological and biochemical characterization of a factor produced spontaneously by adherent cells of human immunodeficiency virus-infected patients inhibiting interleukin-2 receptor alpha chain (Tac) expression on normal T cells.
Topics: Cell Adhesion; Dinoprostone; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; Humans; Interferon Type I; Interferon-gamma; Molecular Weight; Opportunistic Infections; Proteins; Receptors, Interleukin-2; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Regulation of TNF-alpha, IL-1 and IL-6 synthesis in differentiating human monoblastoid leukemic U937 cells.
Topics: Blotting, Northern; Cell Differentiation; Cell Line; Dinoprostone; Humans; Interferon-gamma; Interleukin-1; Interleukin-6; Kinetics; Leukemia, Monocytic, Acute; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Fate of exogenous and endogenous prostaglandins D2 and E2 in the perfused rat liver.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bile; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Kinetics; Liver; Perfusion; Prostaglandin D2; Rats; Tetradecanoylphorbol Acetate | 1991 |
Cellular mechanism of synergistic stimulation of PGE2 production by phorbol diester and Ca2+ ionophore A23187 in cultured Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Dinoprostone; Dogs; Drug Synergism; Kidney; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effects of N-acyl dehydroalanines on phorbol ester-elicited tumor development and other events in mouse skin.
Topics: Alanine; Animals; Cells, Cultured; Dinoprostone; Female; Free Radical Scavengers; Hyperplasia; Luminescent Measurements; Mice; Ornithine Decarboxylase; Oxygen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
The effect of the level of dietary corn oil on mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Capillary Permeability; Cocarcinogenesis; Corn Oil; Dietary Fats; Dinoprostone; Fatty Acids; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Phospholipids; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Selective inhibition of PGE2 production in cells transfected with c-fms encoded CSF-1 receptor genes by the tyrosine kinase inhibitor, ST638.
Topics: Arachidonic Acid; Cells, Cultured; Cinnamates; Dinoprostone; Humans; Indicators and Reagents; Interleukin-3; Ionomycin; Phenotype; Protein-Tyrosine Kinases; Receptors, Colony-Stimulating Factor; Sulfides; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Western; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; NAD; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages.
Topics: Alkaloids; Animals; Cells, Cultured; Dinoprostone; Indoles; Kinetics; Macrophages; Maleimides; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Delineation of the mechanism of inhibition of human T cell activation by PGE2.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blotting, Northern; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cholera Toxin; Colforsin; Cyclic AMP; Dideoxyadenosine; Dinoprostone; Gene Expression; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle.
Topics: Animals; Cell Cycle; Cholera Toxin; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Fibrosarcoma; G1 Phase; Humans; Indomethacin; Interleukin-1; Interleukin-6; Mice; Premedication; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Interleukin-1 stimulates interleukin-6 release from rat anterior pituitary cells in vitro.
Topics: Animals; Cell Separation; Dexamethasone; Dinoprostone; Interleukin-1; Interleukin-6; Lipopolysaccharides; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1991 |
Involvement of prostaglandin E2 in the tumor promoter phorbol ester-caused increase in epidermal cholesterol sulfotransferase activity.
Topics: Animals; Dinoprost; Dinoprostone; Epidermis; Female; Indomethacin; Mice; Sulfotransferases; Tetradecanoylphorbol Acetate | 1991 |
Regulation of synthesis and activity of NAD(+)-dependent 15-hydroxy-prostaglandin dehydrogenase (15-PGDH) by dexamethasone and phorbol ester in human erythroleukemia (HEL) cells.
Topics: Blotting, Western; Carcinogens; Cell Line; Dexamethasone; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Kinetics; Leukemia, Erythroblastic, Acute; Methionine; NAD; Phorbol Esters; Steroids; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1991 |
Pertussis toxin and H-7 distinguish mechanisms involved in eicosanoid release from lipopolysaccharide-primed macrophages. Eicosanoid release from lipopolysaccharide-primed macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprostone; Eicosanoids; Female; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Pertussis Toxin; Piperazines; SRS-A; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Hepatocyte modulation of Kupffer cell prostaglandin E2 production in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Endotoxins; Kupffer Cells; Liver; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
The ratio of macrophage prostaglandin and leukotriene synthesis is determined by the intracellular free calcium level.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Dinoprostone; Drug Synergism; Enzyme Activation; In Vitro Techniques; Indomethacin; Macrophages; Manganese; Mice; Mice, Inbred DBA; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
A glycerol ether induces mobilization and 12-lipoxygenation of arachidonic acid in macrophages. Synergistic effect on mobilization and induction of leukotriene C formation by activators of protein kinase C.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Glyceryl Ethers; Hydroxyeicosatetraenoic Acids; Kinetics; Macrophages; Mice; Peritoneal Cavity; Phosphoproteins; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts.
Topics: Alkaloids; Animals; Biological Transport, Active; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dinoprostone; Fibroblasts; Ionomycin; Kinetics; Mice; Mitogens; Phospholipid Ethers; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Inhibition by protein kinase-C inhibitor and cycloheximide of phorbol ester- and epidermal growth factor-induced arachidonic acid metabolism in cultured porcine thyroid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cycloheximide; Dinoprostone; Epidermal Growth Factor; Isoquinolines; Kinetics; Male; Mice; Piperazines; Protein Kinase C; Sulfonamides; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1990 |
Mechanism of 12-O-tetradecanoylphorbol-13-acetate enhanced metabolism of arachidonic acid in dog urothelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Dogs; Eicosanoids; Epidermal Growth Factor; Epithelium; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Tritium; Urinary Bladder | 1990 |
Differential effects of various skin tumor-promoting agents on prostaglandin E2 release from primary cultures of mouse epidermal cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cells, Cultured; Dinoprostone; Enzyme Activation; Macrophages; Mice; Protein Kinase C; Radioimmunoassay; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Glucocorticoid-induced reduction of prostanoid synthesis in TPA-differentiated U937 cells is mainly due to a reduced cyclooxygenase activity.
Topics: Cell Line; Cycloheximide; Dexamethasone; Dinoprost; Dinoprostone; Humans; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Regulation of eicosanoid biosynthesis by phorbol ester in Madin Darby canine kidney cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cell Line; Dinoprostone; Dogs; Eicosanoids; Kidney; Precipitin Tests; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Carcinogens; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Kinetics; Macrophages; Peritoneal Cavity; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Induction of gene expression by IL-1 in NIH 3T3 cells. Possible requirement of protein kinase C activity and independence from arachidonic acid metabolism.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression; Interleukin-1; Lipoxygenase Inhibitors; Mice; Protein Kinase C; Pyrimidinones; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
The effect of ultraviolet radiation and melanocyte-stimulating hormone on tyrosinase activity in epidermal melanocytes of the mouse.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Cells; Female; Indomethacin; Male; Melanocyte-Stimulating Hormones; Melanocytes; Mice; Monophenol Monooxygenase; Protein Kinase C; Tetradecanoylphorbol Acetate; Theophylline; Ultraviolet Rays | 1990 |
Induction of an interleukin-1 receptor (IL-1R) on monocytic cells. Evidence that the receptor is not encoded by a T cell-type IL-1R mRNA.
Topics: Cell Line; Dexamethasone; Dinoprostone; Escherichia coli; Humans; Interleukin-1; Kinetics; Monocytes; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Diglycerides; Dinoprostone; Dogs; Genes, ras; GTP-Binding Proteins; Guanine Nucleotides; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Isoproterenol; Oncogene Protein p21(ras); Phospholipids; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1990 |
The epidermal growth factor receptor is coupled to a phospholipase A2-specific pertussis toxin-inhibitable guanine nucleotide-binding regulatory protein in cultured rat inner medullary collecting tubule cells.
Topics: Adenosine Diphosphate Ribose; Aluminum; Aluminum Compounds; Animals; Calcium; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Pertussis Toxin; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Endothelin-1 stimulates contraction of rat glomerular mesangial cells and potentiates beta-adrenergic-mediated cyclic adenosine monophosphate accumulation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Cyclic AMP; Dinoprostone; Endothelins; Glomerular Mesangium; Ionomycin; Peptides; Rats; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1990 |
Modulation of interleukin-1 beta production by cyclic AMP in human monocytes.
Topics: Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Monocytes; Tetradecanoylphorbol Acetate | 1990 |
Extracellular ATP stimulates polyphosphoinositide hydrolysis and prostaglandin synthesis in rat renal mesangial cells. Involvement of a pertussis toxin-sensitive guanine nucleotide binding protein and feedback inhibition by protein kinase C.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Diglycerides; Dinoprostone; Down-Regulation; Feedback; Glomerular Mesangium; GTP-Binding Proteins; Inositol Phosphates; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1990 |
Calcium ionophore but not phorbol ester promotes eicosanoids release by proliferating interleukin-3-dependent bone marrow cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bone Marrow Cells; Calcimycin; Calcium; Cell Division; Clone Cells; Dinoprostone; DNA; Female; Hematopoietic Stem Cells; Interleukin-3; Leukotriene B4; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred CBA; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Protein kinase C and intestinal fluid secretion: involvement of prostaglandin E2 but not of 5-hydroxytryptamine.
Topics: Animals; Body Fluids; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Female; Indomethacin; Intestinal Mucosa; Jejunum; Ketanserin; Protein Kinase C; Rats; Rats, Inbred Strains; Serotonin; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Tumor necrosis factor production by Kupffer cells requires protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Dinoprostone; Enzyme Activation; Escherichia coli; Isoquinolines; Kupffer Cells; Lipopolysaccharides; Macrophage Activation; Mice; Mice, Inbred BALB C; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Potential mediation of prostaglandin E2 release from isolated human parietal cells by protein kinase C.
Topics: Calcimycin; Calmodulin; Carbachol; Cell Separation; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Gastric Mucosa; Humans; Parietal Cells, Gastric; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Evidence of a role for protein kinase C in epidermal growth factor-induced prostaglandin E2 synthesis in amnion cells.
Topics: Alkaloids; Amnion; Cell Line; Dinoprostone; Down-Regulation; Drug Synergism; Enzyme Activation; Epidermal Growth Factor; Female; Humans; Pregnancy; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Molecular mechanisms in down-regulation of tumor necrosis factor expression.
Topics: Animals; Cell Line; Cell Nucleus; Cell Survival; Dactinomycin; Dinoprostone; Gene Expression; Humans; Kinetics; Lipopolysaccharides; NF-kappa B; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Ultraviolet stimulated melanogenesis by human melanocytes is augmented by di-acyl glycerol but not TPA.
Topics: Alprostadil; Animals; Cell Division; Diglycerides; Dinoprost; Dinoprostone; Glycerides; Humans; Male; Melanins; Melanocytes; Melanoma, Experimental; Mice; Prostaglandin D2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays | 1990 |
Stimulation of human chondrocyte prostaglandin E2 production by recombinant human interleukin-1 and tumour necrosis factor.
Topics: Adult; Aged; Cartilage, Articular; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Humans; Interleukin-1; Middle Aged; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha | 1990 |
Involvement of protein kinase C in prostaglandin E2-induced catecholamine release from cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; Cytosol; Diglycerides; Dinoprostone; Hydrogen-Ion Concentration; Ionomycin; Kinetics; Ouabain; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Regulatory effect of prostaglandin E2 on fibronectin release from human alveolar macrophages.
Topics: Adult; Bronchoalveolar Lavage Fluid; Cell Count; Cells, Cultured; Dinoprostone; Female; Fibronectins; Humans; Indomethacin; Lipopolysaccharides; Macrophages; Male; Middle Aged; Pulmonary Alveoli; Pulmonary Fibrosis; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Interactive regulation of signalling pathways in bone cells: possible modulation of PGE2-stimulated adenylyl cyclase activity by protein kinase C.
Topics: Adenylyl Cyclases; Animals; Cattle; Dinoprostone; Osteosarcoma; Protein Kinase C; Rats; Salmon; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1990 |
Differential effect of diacylglycerols and phorbol ester on arachidonic acid metabolism in bone marrow-derived macrophages.
Topics: Animals; Arachidonic Acids; Bone Marrow Cells; Diglycerides; Dinoprostone; Glycerides; In Vitro Techniques; Macrophages; Mice; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1990 |
Phorbol ester-induced inhibition of collagen accumulation by human lung fibroblasts.
Topics: Cell Line; Collagen; Cycloheximide; Dinoprostone; Fibroblasts; Histones; Humans; Indomethacin; Kinetics; Lung; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factors | 1990 |
Palytoxin: an extraordinarily potent stimulator of prostaglandin production and bone resorption in cultured mouse calvariae.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Acrylamides; Animals; Bone and Bones; Bone Resorption; Cnidarian Venoms; Cyclic AMP; Dinoprostone; Epidermal Growth Factor; Growth Substances; Indomethacin; Mice; Organ Culture Techniques; Parathyroid Hormone; Peptides; Prostaglandins E; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1987 |
Effect of alpha-fetoprotein and indomethacin on arachidonic acid metabolism in P388D1 macrophages: role of leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; alpha-Fetoproteins; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Dinoprostone; Drug Interactions; Indomethacin; Macrophages; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; SRS-A; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1987 |
Multiple effects of phorbol ester on secretory activity in rabbit gastric glands and parietal cells.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Animals; Cholera Toxin; Dinoprostone; Enzyme Activation; Gastric Mucosa; Histamine Release; In Vitro Techniques; Kinetics; Oxygen Consumption; Parietal Cells, Gastric; Pepsinogens; Pertussis Toxin; Phorbol Esters; Prostaglandins E; Protein Kinase C; Rabbits; Ribose; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Relationship between phospholipase C activation and prostaglandin E2 and cyclic adenosine monophosphate production in rabbit tubular epithelial cells. Effects of angiotensin, bradykinin, and arginine vasopressin.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Bradykinin; Calcium; Cyclic AMP; Dinoprostone; Enzyme Activation; Epithelium; Flurbiprofen; Intracellular Fluid; Ion Channels; Kidney Tubules; Male; Neuropeptides; Pertussis Toxin; Phosphatidylinositols; Prostaglandins E; Rabbits; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1988 |
Bryostatin 1, an activator of protein kinase C, mimics as well as inhibits biological effects of the phorbol ester TPA in vivo and in vitro.
Topics: Animals; Antineoplastic Agents; Arachidonic Acid; Arachidonic Acids; Bryostatins; Calcium; Cell Line; Cells, Cultured; Dinoprostone; DNA Replication; Enzyme Activation; Epidermis; Female; Keratins; Lactones; Macrolides; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Prostaglandins E; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transglutaminases | 1988 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Differential effects of in vitro mycoplasma infection on interleukin-1 alpha and beta mRNA expression in U937 and A431 cells.
Topics: Cell Line; Dinoprostone; Electrophoresis, Agar Gel; Gene Expression Regulation; Humans; Interleukin-1; Microinjections; Mycoplasma Infections; Oocytes; Poly A; Prostaglandins E; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Effect of pertussis toxin on the inhibition of secretory activity by prostaglandin E2, somatostatin, epidermal growth factor and 12-O-tetradecanoylphorbol 13-acetate in parietal cells from rat stomach.
Topics: 1-Methyl-3-isobutylxanthine; Aminopyrine; Animals; Dinoprostone; Epidermal Growth Factor; GTP-Binding Proteins; Histamine; Kinetics; Male; Parietal Cells, Gastric; Pertussis Toxin; Rats; Rats, Inbred Strains; Reference Values; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Stimulation of human amnion prostaglandin E2 production by activators of protein kinase-C.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Female; Humans; Pregnancy; Protein Biosynthesis; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate | 1988 |
Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Carbachol; Cell Line; Cell Transformation, Neoplastic; Cholecystokinin; Cricetinae; Cyclic AMP; Dinoprostone; Female; Kinetics; Ovary; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Activators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; Calcium Channel Blockers; CD2 Antigens; CD5 Antigens; Cell Membrane; Cells, Cultured; Cycloheximide; Diglycerides; Dinoprostone; Enzyme Activation; Flow Cytometry; Humans; Isoquinolines; Membrane Glycoproteins; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Receptors, Immunologic; RNA, Messenger; Sulfonamides; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lipoxygenase; Progesterone; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Ca2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal explants.
Topics: Acetylcholine; Acetylglucosamine; Animals; Atropine; Calcimycin; Calcium; Calmodulin; Colforsin; Dinoprostone; Gastric Fundus; Gastric Mucosa; Glycoproteins; Histamine; Male; Molecular Weight; Organ Culture Techniques; Pentagastrin; Pyloric Antrum; Rabbits; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Differential role of protein kinase C in the action of luteinizing hormone-releasing hormone on hormone production in rat ovarian cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprost; Dinoprostone; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Melitten; Ovary; Progesterone; Prostaglandins; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Synergistic stimulation of prostaglandin E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells.
Topics: Animals; Calcimycin; Cholera Toxin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Melitten; Progesterone; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Regulation of dog urothelial cell arachidonic acid release and prostaglandin E2 synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cell Division; Cells, Cultured; Culture Media; Cycloheximide; Dinoprostone; Dogs; Epithelium; Kinetics; Microscopy, Electron; Tetradecanoylphorbol Acetate; Urinary Bladder | 1989 |
Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Dinoprostone; Ethers, Cyclic; Ionophores; Kinetics; Macrophages; Marine Toxins; Okadaic Acid; Pyrans; Rats; Tetradecanoylphorbol Acetate | 1989 |
Modulation of calcium-induced eicosanoid synthesis in mouse peritoneal macrophages by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Dinoprostone; Fatty Acids, Unsaturated; In Vitro Techniques; Isoquinolines; Macrophages; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1989 |
Decreased prostaglandin production by cholesterol-rich macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteriosclerosis; Cholesterol; Dinoprostone; Epoprostenol; Fatty Acids; Foam Cells; In Vitro Techniques; Macrophages; Male; Mice; Phospholipids; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate | 1989 |
Extracellular ATP stimulates poly(inositol phospholipid) hydrolysis and eicosanoid synthesis in mouse peritoneal macrophages in culture.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cells, Cultured; Dinoprostone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Macrophages; Mice; Mice, Inbred Strains; Peritoneal Cavity; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1989 |
Phorbol myristate enhanced specific incorporation of arachidonic acid into phospholipids through lysophospholipid acyltransferase in cultured smooth muscle cells.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acetyltransferases; Acyl Coenzyme A; Acyltransferases; Analysis of Variance; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Enzyme Activation; Fatty Acids, Unsaturated; Lipopolysaccharides; Lysophosphatidylcholines; Muscle, Smooth; Phosphatidylcholines; Phospholipases; Phospholipids; Rabbits; Substrate Specificity; Tetradecanoylphorbol Acetate | 1989 |
Chondrocyte activation by a putative interleukin-1 derived from lapine polymorphonuclear leukocytes.
Topics: Animals; Cartilage, Articular; Cell Extracts; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-1; Isoelectric Focusing; Male; Microbial Collagenase; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate; Tissue Extracts | 1989 |
Response of rat inner medullary collecting duct to epidermal growth factor.
Topics: Animals; Arachidonic Acids; Cells, Cultured; Cyclic AMP; Dinoprostone; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Kidney Medulla; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C modulates effects of prostanoids on cyclic adenosine monophosphate in guinea pig chief cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Guinea Pigs; Isoquinolines; Male; Pepsinogens; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Radioimmunoassay; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Defining the role of protein kinase C in epinephrine- and bradykinin-stimulated arachidonic acid metabolism in Madin-Darby canine kidney cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cell Line; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Epinephrine; Isoquinolines; Kidney; Piperazines; Protein Kinase C; Receptors, Adrenergic, alpha; Receptors, Bradykinin; Receptors, Neurotransmitter; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Chondrocyte activation by interleukin-1: analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate.
Topics: Animals; Calcimycin; Cartilage, Articular; Dinoprostone; DNA Probes; Drug Synergism; Fibroblast Growth Factors; Gelatinases; Interleukin-1; Metalloendopeptidases; Microbial Collagenase; Pepsin A; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Regulation of insulin-like growth factor-binding protein-1 production in human granulosa-luteal cells.
Topics: Cells, Cultured; Cholera Toxin; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Dinoprostone; Female; Follicle Stimulating Hormone; Granulosa Cells; Homeostasis; Humans; Indomethacin; Kinetics; Progesterone; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins; Tetradecanoylphorbol Acetate | 1989 |
Phorbol esters inhibit chondrogenesis in limb mesenchyme by mechanisms independent of PGE2 or cyclic AMP1.
Topics: Animals; Cartilage; Cells, Cultured; Chick Embryo; Cyclic AMP; Dinoprostone; Extremities; Kinetics; Tetradecanoylphorbol Acetate | 1989 |
Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis.
Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cyclosporine; Cyclosporins; Dermatitis; Dinoprostone; Enzyme Activation; Epidermis; Hyperplasia; Interleukins; Mice; Mice, Hairless; Ornithine Decarboxylase; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transglutaminases | 1989 |
Induction of ornithine decarboxylase in rat liver by phorbol ester is mediated by prostanoids from Kupffer cells.
Topics: Alprostadil; Animals; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; In Vitro Techniques; Indomethacin; Kupffer Cells; Liver; Ornithine Decarboxylase; Prostaglandin D2; Prostaglandins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Regulation of eicosanoid synthesis in mouse peritoneal macrophages by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acids; Diglycerides; Dinoprostone; Isoquinolines; Macrophages; Mice; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Cyclosporin A inhibits protein kinase C activity: a contributing mechanism in the development of nephrotoxicity?
Topics: Animals; Cell Line; Cyclosporins; Cytosol; Dinoprostone; Dogs; Enzyme Activation; Epithelium; Glomerular Mesangium; Kidney; Kidney Diseases; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1989 |
Differential effects of phorbol esters on PGE2 and bradykinin-induced elevation of [Cai2+] in MDCK cells.
Topics: Animals; Benzofurans; Bradykinin; Calcium; Cell Line; Dinoprostone; Fluorescent Dyes; Fura-2; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Prostaglandins; Tetradecanoylphorbol Acetate | 1989 |
Bradykinin stimulated PGE2 production is independent of changes in intracellular calcium in MDCK cells.
Topics: Animals; Bradykinin; Calcium; Cell Line; Dinoprostone; Kinetics; Lanthanum; Tetradecanoylphorbol Acetate | 1989 |
Prostaglandin E2 inhibits proliferation but not interleukin-2 production by phorbol ester plus calcium ionophore-activated murine T cell clones.
Topics: Animals; Clone Cells; Dinoprostone; Indomethacin; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Comparative study of natural and synthetic retinoids as inhibitors of arachidonic acid release and metabolism in rat peritoneal macrophages.
Topics: Animals; Calcimycin; Dinoprostone; Fatty Acids, Unsaturated; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Peritoneal Lavage; Phospholipases A; Prostaglandins E; Rats; Rats, Inbred Strains; Retinoids; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1987 |
Effect of phorbol ester and calcium ionophore on chloride secretion in canine tracheal epithelium.
Topics: Calcimycin; Chlorides; Cyclic AMP; Dinoprostone; Drug Synergism; Electric Conductivity; Epithelium; Indomethacin; Prostaglandins E; Protein Kinase C; Secretory Rate; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Na+-dependent elevation of the acidic cell surface pH (microclimate pH) of rat jejunal villus cells induced by cyclic nucleotides and phorbol ester: possible mediators of the regulation of the Na+/H+ antiporter.
Topics: Amiloride; Animals; Bucladesine; Calcimycin; Carrier Proteins; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Hydrogen-Ion Concentration; Jejunum; Male; Microvilli; Phorbol Esters; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Theophylline | 1988 |
Induction of glucagon sensitivity in a transformed kidney cell line by prostaglandin E2 and its inhibition by epidermal growth factor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood; Cell Differentiation; Cell Line, Transformed; Cyclic AMP; Dinoprostone; Dogs; Epidermal Growth Factor; Glucagon; Kidney; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate | 1987 |
Cooperative interactions of protein kinase C and cAMP-dependent protein kinase systems in human promyelocytic leukemia HL60 cells.
Topics: Biological Transport; Bucladesine; Cell Differentiation; Dinoprostone; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Male; Membrane Proteins; Middle Aged; Neoplasm Proteins; Phosphorylation; Prostaglandins E; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Involvement of two intracellular messenger systems, protein kinase C and cyclic AMP, in the regulation of c-fos gene expression in human promyelocytic leukemia (HL-60) cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Diglycerides; Dinoprostone; Gene Expression Regulation; Humans; Kinetics; Leukemia, Myeloid; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Fatty Acids; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by glucocorticoids of PGE2 and ACTH secretion induced by phorbol esters and EGF in rat pituitary cells.
Topics: Adrenocorticotropic Hormone; Animals; Carcinogens; Cells, Cultured; Dexamethasone; Dinoprostone; Glucocorticoids; Kinetics; Male; Phorbol Esters; Pituitary Gland, Anterior; Prostaglandins E; Quinacrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Triamcinolone Acetonide | 1988 |
Characterization of 12-O-tetradecanoyl-phorbol-13 acetate mediated ACTH release.
Topics: Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Dinoprostone; Dose-Response Relationship, Drug; Female; Hydrocortisone; Nifedipine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Prostaglandin E2 and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells.
Topics: Antigen-Antibody Reactions; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; In Vitro Techniques; Inositol Phosphates; Lymphocyte Activation; Phosphatidylinositols; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Agonist but not phorbol ester induced desensitization of human lymphocyte prostaglandin receptor is dependent on tubulin polymerization.
Topics: Benzimidazoles; Binding, Competitive; Carcinogens; Colchicine; Cyclic AMP; Dinoprostone; Humans; Leukemia, T-Cell; Nocodazole; Phorbol 12,13-Dibutyrate; Phorbol Esters; Receptors, Prostaglandin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tubulin; Tumor Cells, Cultured | 1988 |
PGE2-induced cyclic AMP accumulation in human CD4+ T cells is strongly enhanced during the CD2-mediated activatory process.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Isoproterenol; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of prostaglandin E2-induced phosphoinositide metabolism by phorbol ester in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Cattle; Cell Membrane; Cells, Cultured; Chromaffin Granules; Dinoprostone; Inositol Phosphates; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Regulation of the production of placental protein 5 by human endometrial stromal cells; the role of prostaglandins E2 and F2 alpha.
Topics: Cells, Cultured; Cholera Toxin; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endometrium; Enzyme Activation; Female; Glycoproteins; Humans; Kinetics; Pregnancy Proteins; Progesterone; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol 13-acetate (TPA)-type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide.
Topics: Acrylamides; Animals; Carcinogens; Cnidarian Venoms; Cycloheximide; Dinoprostone; Lyngbya Toxins; Macrophages; Male; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
Prostaglandin E receptor enhancement of catecholamine release may be mediated by phosphoinositide metabolism in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcimycin; Calcium; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Cyclic AMP; Dinoprostone; Muscarine; Ouabain; Phosphatidylinositols; Prostaglandins E; Protein Kinase C; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1988 |
Cyclic AMP-mediated alteration of the CD2 activation process in human T lymphocytes. Preferential inhibition of the phosphoinositide cycle-related transduction pathway.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Bucladesine; Calcimycin; Calcium; CD2 Antigens; Cell Line; Cyclic AMP; Diglycerides; Dinoprostone; Humans; In Vitro Techniques; Inositol Phosphates; Lymphocyte Activation; Phosphatidylinositols; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Differentiation of human neuroblastoma cells: marked potentiation of prostaglandin E-stimulated accumulation of cyclic AMP by retinoic acid.
Topics: Adenylyl Cyclases; Alprostadil; Bucladesine; Cell Differentiation; Cyclic AMP; Dinoprostone; Drug Synergism; Humans; Indomethacin; Nerve Growth Factors; Neuroblastoma; Prostaglandins E; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tachyphylaxis; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion).
Topics: Animals; Cocarcinogenesis; Dinoprost; Dinoprostone; Epidermis; Indomethacin; Mice; Papilloma; Phorbol Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Modulation by glycyrrhetinic acid derivatives of TPA-induced mouse ear oedema.
Topics: Animals; Dinoprostone; Ear Diseases; Edema; Glycyrrhetinic Acid; Male; Mice; Mice, Inbred Strains; SRS-A; Tetradecanoylphorbol Acetate | 1989 |
Dehydroepiandrosterone and two structural analogs inhibit 12-O-tetradecanoylphorbol-13-acetate stimulation of prostaglandin E2 content in mouse skin.
Topics: Animals; Dehydroepiandrosterone; Dinoprostone; Mice; Prostaglandins E; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1988 |
Prostaglandins E1 and E2 enhance the stimulation of superoxide release by 1-oleoyl-2-acetylglycerol from human neutrophils.
Topics: Alprostadil; Calcimycin; Diglycerides; Dinoprostone; Enzyme Activation; Glycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Protein Kinase C; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Inhibition of vasopressin-stimulated water flow in toad bladder by phorbol myristate acetate, dioctanoylglycerol, and RHC-80267. Evidence for modulation of action of vasopressin by protein kinase C.
Topics: Animals; Anura; Biological Transport, Active; Body Water; Cyclic AMP; Cyclohexanes; Cyclohexanones; Diglycerides; Dinoprostone; Epithelium; Female; Glycerides; Lipoprotein Lipase; Mucous Membrane; Phorbols; Prostaglandins E; Protein Kinase C; Serous Membrane; Tetradecanoylphorbol Acetate; Urinary Bladder; Vasopressins | 1985 |
Differential effects of tumor promoters on cAMP production: inhibition of receptor-mediated and potentiation of cholera toxin-mediated stimulation.
Topics: Animals; Carcinogens; Cholera Toxin; Cyclic AMP; Dinoprostone; Drug Synergism; GTP-Binding Proteins; In Vitro Techniques; Kinetics; Mice; Mice, Inbred BALB C; Prostaglandins E; Receptors, Mitogen; Tetradecanoylphorbol Acetate; Thymus Gland | 1985 |
Interleukin 2 modulation of adenylate cyclase. Potential role of protein kinase C.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Dinoprostone; DNA Replication; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Interleukin-2; Mice; Prostaglandins E; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.
Topics: Animals; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Diglycerides; Dinoprostone; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Indomethacin; Norepinephrine; Prostaglandins E; Protein Kinase C; Rats; Secretory Rate; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Role of calcium on TPA-induced secretion of ACTH and PGE2 by pituitary cells: effect of dexamethasone.
Topics: Adrenocorticotropic Hormone; Animals; Calcimycin; Calcium; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Male; Phorbols; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Effect of interferon-gamma and 1 alpha,25-dihydroxyvitamin D3 on superoxide anion, prostaglandins E2, and mononuclear cell factor production by U937 cells.
Topics: Calcitriol; Cell Differentiation; Cell Line; Dinoprostone; Humans; Interferon-gamma; Microbial Collagenase; Monocytes; Monokines; Prostaglandins E; Protein Biosynthesis; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Effect of prostaglandin E2 on ACTH and beta-endorphin release from rat adenohypophysis in vitro after secretagogues which can mimic various first or second messengers.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Barium; beta-Endorphin; Calcium; Dinoprostone; Endorphins; In Vitro Techniques; Male; Pituitary Gland, Anterior; Potassium; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1986 |
Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Bucladesine; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Lymphocyte Activation; Membrane Proteins; Monocytes; Nucleotides, Cyclic; Prostaglandins E; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Induction and regulation of human interleukin 2 gene expression: significance of protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-2; Isoquinolines; Lymphocytes; Mitoguazone; Ornithine; Phytohemagglutinins; Piperazines; Prostaglandins E; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine | 1986 |
Macrophage activation in rat models of inflammation and arthritis: determination of markers of stages of activation.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytotoxicity, Immunologic; Dinoprostone; Inflammation; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Phagocytosis; Prostaglandins E; Rats; Rats, Inbred Lew; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of human B cell responsiveness by prostaglandin E2.
Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprost; Dinoprostone; Ethers; Humans; Ionomycin; Lymphocyte Activation; Lymphokines; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Vinblastine | 1987 |
Substances affecting the infection and replication of human immunodeficiency virus (HIV).
Topics: Cell Line; Cytopathogenic Effect, Viral; Deltaretrovirus; Dinoprostone; HIV; Humans; Interferon-gamma; Prostaglandins E; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin; Virus Replication; Zidovudine | 1986 |
Electronic determinants of the anti-inflammatory action of benzoic and salicylic acids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Benzoic Acid; Chemical Phenomena; Chemistry, Physical; Cyclooxygenase Inhibitors; Dinoprostone; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Macrophages; Mice; Prostaglandins E; Salicylates; Salicylic Acid; Secretory Rate; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
Comparative effects of polymyxin B, phorbol ester and bryostatin on protein phosphorylation, protein kinase C translocation, phospholipid metabolism and differentiation of HL60 cells.
Topics: Bryostatins; Cell Adhesion; Cell Differentiation; Cell Line; Dinoprostone; Humans; Lactones; Leukemia, Myeloid, Acute; Macrolides; Phorbol Esters; Phosphatidylcholines; Phospholipids; Phosphorylation; Polymyxin B; Polymyxins; Prostaglandins E; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C activators and bradykinin selectively inhibit vasopressin-stimulated cAMP synthesis in MDCK cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Glucagon; Isoquinolines; Piperazines; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
Rat macrophage treatment with lipopolysaccharide leads to a reduction in respiratory burst product secretion and a decrease in NADPH oxidase affinity.
Topics: Animals; Cells, Cultured; Depression, Chemical; Dinoprostone; Hydrogen Peroxide; Indomethacin; Kinetics; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Oxidation-Reduction; Prostaglandins E; Rats; Rats, Inbred F344; Rats, Inbred Lew; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.
Topics: Calcimycin; Calcium; Cyclic AMP; Cytoplasm; Dinoprostone; Enzyme Activation; Humans; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Prostaglandins E; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-2; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; GTP-Binding Proteins; Hybrid Cells; Mice; Neuroblastoma; Phosphorylation; Prostaglandins E; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Interleukin-2; Lymphocyte Activation; Mice; Prostaglandins E; Protein Biosynthesis; Proto-Oncogene Proteins; Proto-Oncogenes; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Calcium regulation of tissue plasminogen activator and prostaglandin biosynthesis in HeLa cells.
Topics: Calcimycin; Calcium; Dinoprostone; HeLa Cells; Humans; Kinetics; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1986 |
Release of cytoprotective PGE2 from cultured macrophages induced by antacids and sucralfate.
Topics: Aluminum; Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Dinoprostone; Macrophages; Male; Mice; Mice, Inbred Strains; Prostaglandins E; Sucralfate; Tetradecanoylphorbol Acetate | 1986 |
Eicosanoid synthesis by cultured human urothelial cells: potential role in bladder cancer.
Topics: Arachidonic Acids; Bradykinin; Calcimycin; Carcinogens; Dinoprostone; Epinephrine; Epithelium; Humans; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin; Ureter; Urinary Bladder Neoplasms | 1986 |
Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Line; Cycloheximide; Dinoprostone; Gene Expression Regulation; Growth Substances; Histocompatibility Antigens Class II; Interleukin-4; Lymphokines; Mice; Prostaglandins E; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1986 |
Early changes in the arachidonic acid metabolism of HeLa cells in response to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and related compounds.
Topics: Arachidonic Acid; Arachidonic Acids; Carcinogens; Culture Media; Cycloheximide; Dinoprostone; HeLa Cells; Humans; Membrane Lipids; Mitogens; Phorbol Esters; Phospholipids; Prostaglandins E; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; DNA Replication; Female; Flurbiprofen; Indomethacin; Mice; Ornithine Decarboxylase; Prostaglandins E; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Effects of the phorbolester TPA and of the ionophore A 23187 on phospholipase A2 and C activities in the mouse epidermal cell line HEL-30.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carcinogens; Cell Line; Dinoprostone; Enzyme Activation; Epidermis; Mice; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Stimulation of arachidonic acid metabolism in rat peritoneal macrophages by thapsigargin, a non-(12-O-tetradecanoylphorbol-13-acetate) (TPA)-type tumor promoter.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprostone; Macrophages; Peritoneal Cavity; Plant Extracts; Prostaglandins E; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thapsigargin | 1987 |
Correlation of immunogenicity and production of ornithine by peritoneal macrophages.
Topics: Animals; Arginase; Cytotoxicity, Immunologic; Dinoprostone; Glutathione; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Ornithine; Peritoneal Cavity; Prostaglandins E; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of prostaglandin E2 production by phorbol esters and epidermal growth factor in porcine thyroid cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; Kinetics; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1987 |
The lack of PDGE-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Cells, Cultured; Dinoprostone; Kinetics; Mice; Mice, Inbred Strains; Oncogenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2.
Topics: Animals; Capillary Permeability; Dinoprostone; Edema; Histamine; Indomethacin; Inflammation; Lyngbya Toxins; Methysergide; Neutrophils; Prostaglandins E; Pyrilamine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Chromatography, High Pressure Liquid; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Female; Follicle Stimulating Hormone; Gas Chromatography-Mass Spectrometry; Granulosa Cells; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate | 1987 |
Mitogenic action of phorbol ester TPA and calcium ionophore A23187 on human cord and maternal/adult peripheral lymphocytes: regulation by prostaglandin E2.
Topics: Adult; Calcimycin; Cell Division; Dinoprostone; Drug Interactions; Female; Fetal Blood; Humans; Indomethacin; Infant, Newborn; Lymphocyte Activation; Lymphocytes; Pregnancy; Prostaglandins E; Tetradecanoylphorbol Acetate | 1987 |
Epidermal growth factor (EGF), tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) and calcium ionophore A23187 increase cytoplasmic free calcium and stimulate arachidonic acid release and PGE2/6-keto PGF1 alpha production in cultured porcine thyroi
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Calcium; Cells, Cultured; Cytoplasm; Dinoprostone; Epidermal Growth Factor; Fluorescent Dyes; Fura-2; Kinetics; Prostaglandins; Prostaglandins E; Spectrometry, Fluorescence; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1987 |
Role for protein kinase C in A23187 induced glomerular arachidonate release and PGE2 production.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Kidney Glomerulus; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C mediates endotoxin and zymosan-induced prostaglandin synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Wall; Dinoprostone; Endotoxins; Leukemia, Experimental; Mice; Prostaglandins; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Epidermal growth factor is synergistic with phorbol esters and vasopressin in stimulating arachidonate release and prostaglandin production in renal glomerular mesangial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Dinoprostone; Drug Synergism; Epidermal Growth Factor; Glomerular Mesangium; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Calcium ionophore and phorbol myristate acetate synergistically inhibited proteoglycan biosynthesis in articular chondrocytes by prostaglandin independent mechanism.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Calcimycin; Cartilage, Articular; Diglycerides; Dinoprostone; Drug Synergism; Indomethacin; Prostaglandins E; Proteoglycans; Pyrazoles; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Characteristics of bradykinin and TPA increases in the PGE2 levels of human urothelial cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium; Cells, Cultured; Cycloheximide; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; In Vitro Techniques; Prostaglandins E; Tetradecanoylphorbol Acetate; Ureter | 1988 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Inhibition by gossypol of tumor promoter-induced arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Gossypol; Macrophages; Male; Peritoneal Cavity; Plant Extracts; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells.
Topics: Amnion; Calcium; Cells, Cultured; Colforsin; Dinoprostone; Egtazic Acid; Epithelium; Humans; Inositol Phosphates; Isoproterenol; Oxytocin; Prostaglandins E; Protein Kinase C; Reference Values; Ritodrine; Sugar Phosphates; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Stimulation of release of prostaglandins and thromboxanes from isolated guinea pig lung cells by bradykinin, f-Met-Leu-Phe, phorbol myristate, ionophore A23187, and leukotrienes.
Topics: Animals; Bradykinin; Calcimycin; Dinoprostone; Guinea Pigs; In Vitro Techniques; Leukotrienes; Lung; N-Formylmethionine Leucyl-Phenylalanine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Pharmacological modification of 12-0-tetradecanoylphorbol-13-acetate induced inflammation and epidermal cell proliferation in mouse skin.
Topics: Animals; Colchicine; Cyclooxygenase Inhibitors; Dermatitis, Contact; Dinoprostone; Ear; Edema; Epidermis; Female; Lipoxygenase Inhibitors; Mice; Neutrophils; Prednisolone; Protein Biosynthesis; Tetradecanoylphorbol Acetate | 1988 |
Regulation of eicosanoid biosynthesis in vitro and in vivo by the marine natural product manoalide: a potent inactivator of venom phospholipases.
Topics: 6-Ketoprostaglandin F1 alpha; Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; In Vitro Techniques; Macrophages; Male; Mice; Phospholipases; Phospholipases A; Phospholipases A2; SRS-A; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Phorbol esters and diacylglycerols amplify bradykinin-stimulated prostaglandin synthesis in Swiss 3T3 fibroblasts. Possible independence from protein kinase C.
Topics: Animals; Bradykinin; Cells, Cultured; Diglycerides; Dinoprostone; Glycerides; Kinetics; Mice; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester-induced stimulation of prostaglandin biosynthesis in human amnion cells.
Topics: Amnion; Dinoprostone; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Tetradecanoylphorbol Acetate | 1988 |
Role for protein kinase C in the modulation of glomerular PGE2 production by angiotensin II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Dinoprostone; Female; Isoquinolines; Kidney Glomerulus; Phorbol Esters; Phorbols; Piperazines; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Net prostaglandin release by perfused rat liver after stimulation with phorbol 12-myristate 13-acetate.
Topics: Animals; Blood Pressure; Dinoprostone; Female; Glucose; Kupffer Cells; Liver; Perfusion; Portal Vein; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of bone collagen synthesis by the tumor promoter phorbol 12-myristate 13-acetate.
Topics: Alkaline Phosphatase; Animals; Bone and Bones; Collagen; Dinoprostone; DNA Replication; Fetus; Organ Culture Techniques; Osteoblasts; Protein Biosynthesis; Rats; Reference Values; Tetradecanoylphorbol Acetate | 1988 |
Epidermal growth factor, vanadate, and 12-O-tetradecanoylphorbol-13-acetate inhibit growth and stimulate prostaglandin E2 production in A431 cells.
Topics: Cell Line; Dinoprostone; Epidermal Growth Factor; Humans; Prostaglandins E; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tumor Cells, Cultured; Vanadates | 1988 |
7,8-Benzoflavone: an inhibitor of prostaglandin synthesis and ornithine decarboxylase in murine epidermal cultures.
Topics: Animals; Benzoflavones; Cells, Cultured; Dinoprostone; Flavonoids; Mice; Mice, Inbred Strains; Ornithine Decarboxylase Inhibitors; Prostaglandins; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate | 1986 |
Growth requirements of murine bone marrow macrophages in serum-free cell culture.
Topics: Alprostadil; Animals; Bone Marrow Cells; Cell Division; Cells, Cultured; Culture Media; Dexamethasone; Dinoprostone; DNA Replication; Female; Kinetics; L Cells; Macrophages; Mice; Mice, Inbred C57BL; Prostaglandins E; Tetradecanoylphorbol Acetate; Thymidine; Tretinoin | 1986 |
Time-dependent changes in protein kinase C distribution and disappearance in phorbol ester-treated human osteosarcoma cells.
Topics: Cell Line; Dinoprostone; Enzyme Activation; Humans; Osteosarcoma; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tissue Distribution | 1987 |
Epidermal growth factor (EGF) and tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) stimulate PG synthesis and thymidine incorporation in cultured porcine thyroid cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; Prostaglandins; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thymidine; Thyroid Gland | 1987 |
Inhibition of adenylate cyclase by IL 2 in human T lymphocytes is mediated by protein kinase C.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Calcium; Dinoprostone; Humans; In Vitro Techniques; Interleukin-2; Kinetics; Lymphocyte Activation; Prostaglandins E; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Structural correlations of phorbol-ester-induced stimulation of PGE2 production by human rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Dinoprostone; Humans; Phorbol Esters; Phorbols; Prostaglandins E; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |
Role of prostanoids and lipid peroxides as mediators of the 12-O-tetradecanoylphorbol-13-acetate effect on cell growth.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Cell Count; Cell Division; Cells, Cultured; Dinoprostone; Fibroblasts; Guinea Pigs; Humans; Lipid Peroxides; Malondialdehyde; Muscle, Smooth; Phorbols; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate-protein complex mimics bioactivity of human IL-1. 1. Direct evidence that PMA temporarily enters and is released from cellular compartment during superinduction protocol.
Topics: Animals; Binding, Competitive; Cell Compartmentation; Cell Line; Dinoprostone; Humans; Immune Sera; Interleukin-1; Leukemia P388; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Proteins; Phorbols; Phytohemagglutinins; Prostaglandins E; Pyrogens; Rabbits; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Interferon Type I; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C3H; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1985 |
Arachidonic acid metabolism in cultured mouse keratinocytes.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Blood; Calcimycin; Cells, Cultured; Culture Media; Dinoprostone; Mice; Phospholipases; Phospholipids; Prostaglandins E; Skin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tritium | 1985 |
Arachidonic acid metabolism in murine fibrosarcoma cells with differing in vivo and in vitro characteristics.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Adhesion; Cell Line; Chemotaxis; Dinoprostone; Fibronectins; Fibrosarcoma; Laminin; Lipoxygenase; Mice; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1985 |
The macrophage adherence phenomenon: its relationship to prostaglandin E2 and superoxide anion production and changes in transmembrane potential.
Topics: Animals; Ascitic Fluid; Cell Adhesion; Cells, Cultured; Dinoprostone; Female; Macrophages; Membrane Potentials; Mice; Prostaglandins E; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
The modulation of human basophil histamine release by products of the 5-lipoxygenase pathway.
Topics: Allergens; Antibodies, Anti-Idiotypic; Antigens, Plant; Arachidonic Acids; Basophils; Calcimycin; Dimaprit; Dinoprostone; Histamine Release; Humans; Immunoglobulin E; Leukotrienes; Lipoxygenase; Plant Proteins; Pollen; Prostaglandins E; Tetradecanoylphorbol Acetate; Thiourea | 1982 |
Effect of prostaglandin D2 in modulating histamine release from human basophils.
Topics: Arachidonic Acids; Basophils; Calcimycin; Dimaprit; Dinoprostone; Histamine Release; Humans; Indomethacin; Leukotrienes; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Receptors, Histamine H2; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiourea | 1984 |
Modulation by retinoic acid and corticosteroids of collagenase production by rabbit synovial fibroblasts treated with phorbol myristate acetate or poly(ethylene glycol).
Topics: Animals; Cells, Cultured; Dexamethasone; Dinoprostone; Enzyme Induction; Fibroblasts; Microbial Collagenase; Phorbols; Polyethylene Glycols; Prednisolone; Prostaglandins E; Rabbits; Synovial Fluid; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Decreased accumulation of cyclic adenosine 3',5'-monophosphate in "ischemic" skin after 12-0-tetradecanoyl-phorbol-13-acetate treatment.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetone; Adenosine; Animals; Cyclic AMP; Dinoprostone; Female; Histamine; In Vitro Techniques; Ischemia; Isoproterenol; Mice; Phorbols; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate | 1982 |
Collagenase production by cloned populations of rabbit synovial fibroblasts.
Topics: Animals; Cell Division; Clone Cells; Dinoprostone; Fibroblasts; Microbial Collagenase; Prostaglandins E; Rabbits; Synovial Fluid; Tetradecanoylphorbol Acetate | 1981 |
Epidermal growth factor and phorbol ester actions on human osteosarcoma cells. Characterization of response and nonresponsive cell lines.
Topics: Calcium; Cell Line; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Humans; Osteosarcoma; Phorbol Esters; Phorbols; Prostaglandins E; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1982 |
Effect of transmethylation-reaction and increased levels of cAMP on superoxide generation of guinea-pig macrophages induced with wheat germ agglutinin and phorbor myristate.
Topics: Animals; Bucladesine; Cyclic AMP; Dinoprostone; Guinea Pigs; Lectins; Macrophages; Methylation; Oxygen; Phorbols; Prostaglandins E; Superoxides; Tetradecanoylphorbol Acetate; Tubercidin; Wheat Germ Agglutinins | 1983 |
Calcium ionophore A-23187 and 12-O-tetradecanoyl-phorbol-13-acetate stimulation of prostaglandin synthesis in herpes simplex virus type 2-transformed rat cells.
Topics: Animals; Calcimycin; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dinoprost; Dinoprostone; Embryo, Mammalian; Fibrosarcoma; Kinetics; Neoplasm Metastasis; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1984 |
Inhibition of human IL 2 production by MDP and derivatives.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adult; Dinoprostone; Female; Humans; Immunosuppressive Agents; Indomethacin; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Phytohemagglutinins; Prostaglandins E; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1984 |
12-O-tetradecanoylphorbol-13-acetate stimulates release of arachidonic acid, prostaglandin E2 and prostaglandin F2 alpha from TPA nonproliferative variants of 3T3 cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Division; Cell Line; Dinoprost; Dinoprostone; Fibroblasts; Mice; Phorbols; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate | 1983 |
Regulation of arachidonic acid metabolism in Madin-Darby canine kidney cells. Comparison of A23187 and 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cycloheximide; Dinoprostone; Dogs; Kidney; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate | 1984 |
Pharmacological control of leukotriene and prostaglandin production from mouse peritoneal macrophages.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Calcimycin; Dinoprostone; Drug Interactions; In Vitro Techniques; Macrophages; Mice; Peritoneum; Prostaglandins; Prostaglandins E; SRS-A; Tetradecanoylphorbol Acetate | 1984 |
Prostaglandin biosynthesis by a human macrophage-like cell line, U937.
Topics: Arachidonic Acids; Carbon Radioisotopes; Cell Line; Chromatography, Thin Layer; Dinoprostone; Humans; Indomethacin; Macrophages; Prostaglandins E; Radioimmunoassay; Tetradecanoylphorbol Acetate; Zymosan | 1983 |
Magnitude of ornithine decarboxylase induction by epidermal mitogens: effect of the assay technique.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cells, Cultured; Cholera Toxin; Dinoprostone; Enzyme Induction; Fibroblasts; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mitogens; Ornithine Decarboxylase; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate | 1984 |
Relationship between mezerein-mediated biological responses and phorbol ester receptor occupancy.
Topics: Binding, Competitive; Caenorhabditis elegans Proteins; Carrier Proteins; Dinoprostone; Diterpenes; Epidermal Growth Factor; Humans; Kinetics; Osteosarcoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Prostaglandins E; Protein Kinase C; Receptors, Drug; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Early induction of the arachidonic acid cascade and stimulation of DNA synthesis by TPA in murine and guinea pig epidermal cells in culture.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cells, Cultured; Dinoprost; Dinoprostone; DNA; Epidermis; Guinea Pigs; Indomethacin; Mice; Ornithine Decarboxylase; Phorbols; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate | 1982 |
On the relationship between epidermal hyperproliferation and skin tumor promotion.
Topics: Calcimycin; Cell Division; Cocarcinogenesis; Dinoprost; Dinoprostone; Epidermal Cells; Hyperplasia; Indomethacin; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity by phospholipase A2 inhibitors and lipoxygenase inhibitor.
Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Carboxy-Lyases; Catechols; Dinoprostone; Female; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Ornithine Decarboxylase; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandins E; Quinacrine; Skin; Tetracaine; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity by lipoxygenase inhibitors: possible role of product(s) of lipoxygenase pathway.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Carboxy-Lyases; Dinoprostone; Female; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase Inhibitors; Phorbols; Prostaglandins E; Pyrazoles; Skin; Tetradecanoylphorbol Acetate | 1982 |
Stimulation by retinoic acid of prostaglandin production and its inhibition by tumor promoters in mouse myeloid leukemia cells.
Topics: Animals; Cell Line; Dinoprostone; Enzyme Induction; Indomethacin; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Muramidase; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Modification of growth and differentiation of myeloid leukemia cells by tumor promoters.
Topics: Animals; Blood; Cell Differentiation; Cell Line; Chromatography, Gel; Culture Media; Dinoprostone; Leukemia, Myeloid; Mice; Phagocytosis; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate | 1982 |
Tumour-promoter-induced proliferation of 3T3 cells in independent of prostaglandin release and ornithine decarboxylase induction.
Topics: Animals; Carboxy-Lyases; Cell Division; Cell Line; Diamines; Dinoprostone; DNA; Enzyme Induction; Epoprostenol; Mice; Ornithine Decarboxylase; Phorbols; Prostaglandins; Prostaglandins E; Tetradecanoylphorbol Acetate | 1982 |
Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprostone; Enzyme Inhibitors; Female; Hypersensitivity, Delayed; Indoles; Macrophages, Peritoneal; Maleimides; Mice; Mice, Inbred BALB C; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cell Line, Transformed; Cinnamates; Dinoprostone; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; Isoquinolines; Piperazines; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1995 |
Interleukin-1 beta-stimulated prostaglandin synthesis by human decidual cells is independent of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Decidua; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Interleukin-1; Isoquinolines; Piperazines; Pregnancy; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1995 |
Interleukin-1 beta induces the synthesis and activity of cytosolic phospholipase A2 and the release of prostaglandin E2 in human amnion-derived WISH cells.
Topics: Amnion; Blotting, Western; Cell Line; Chorion; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Hot Temperature; Humans; Hydrogen-Ion Concentration; Interleukin-1; Kinetics; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1995 |
PGE2 induces the transition from non-adherent to adherent bone marrow mesenchymal precursor cells via a cAMP/EP2-mediated mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Adhesion; Cells, Cultured; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Hematopoietic Stem Cells; Kinetics; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of MAP kinase by prostaglandin E2 and forskolin in rat renal mesangial cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Glomerular Mesangium; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
Human immunodeficiency virus type 1 envelope protein does not stimulate either prostaglandin formation or the expression of prostaglandin H synthase in THP-1 human monocytes/macrophages.
Topics: Animals; Antibodies, Monoclonal; CD4 Antigens; Cell Differentiation; Cell Line; CHO Cells; Cricetinae; Dinoprostone; Eicosanoids; Enzyme Activation; Gene Expression; HIV Envelope Protein gp120; HIV-1; Humans; Isoenzymes; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Macrophages; Monocytes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; src-Family Kinases; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1995 |
Expression of hepatocyte growth factor is up-regulated through activation of a cAMP-mediated pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Infant; Kinetics; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1994 |
Involvement of protein kinase A and C in the production of interleukin-1 alpha-induced prostaglandin E2 from mouse osteoblast-like cell line, MC3T3-E1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dinoprostone; Humans; Indoles; Indomethacin; Interleukin-1; Isoquinolines; Kinetics; Mice; Osteoblasts; Piperazines; Protein Kinase C; Pyrroles; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Physiological Phenomena; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Male; Muscle, Smooth; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Regulation of the release of interleukin-6 from human astrocytoma cells.
Topics: Adenylyl Cyclases; Alzheimer Disease; Astrocytoma; Calcium; Cycloheximide; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Histamine; Humans; Indomethacin; Inositol Phosphates; Interleukin-1; Interleukin-6; Kinetics; Protein Kinase C; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Transcriptional regulation of plasminogen activator inhibitor-1 expression in human synovial fibroblasts by prostaglandin E2: mediation by protein kinase A and role of interleukin-1.
Topics: 1-Methyl-3-isobutylxanthine; Blood; Cadaver; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Bradykinin-induced in vitro contraction of rat mesangial cells via a B2 receptor type.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic beta-2 Receptor Antagonists; Angiotensin II; Animals; Arginine Vasopressin; Bombesin; Bradykinin; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cells, Cultured; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelins; Fatty Acids, Unsaturated; Glomerular Mesangium; Indomethacin; Kinetics; Naphthalenes; Neomycin; Polycyclic Compounds; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Quinacrine; Rats; Receptors, Adrenergic, beta-2; Surface Properties; Tetradecanoylphorbol Acetate; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Induction of serine and threonine protein phosphorylation by endotoxin-associated protein in murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Bacterial Proteins; Dinoprostone; Endotoxins; Female; Ionomycin; Lipid A; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C3H; Molecular Weight; Phosphoproteins; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Downregulation of phorbol 12-myristate 13-acetate-induced tumor necrosis factor-alpha and interleukin-1 beta production and gene expression in human monocytic cells by human alpha-fetoprotein.
Topics: alpha-Fetoproteins; Cell Line; Cytokines; Dinoprostone; Gene Expression; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Monocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Inhibition of serine/threonine protein phosphatases enhances agonist-stimulated cAMP accumulation in UMR 106 osteoblast-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Antifungal Agents; Colforsin; Cyclic AMP; Dinoprostone; Ethers, Cyclic; Humans; Kinetics; Marine Toxins; Okadaic Acid; Osteoblasts; Oxazoles; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Serine-Threonine Kinases; Proteins; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Inhibition of the arachidonic acid pathway prevents induction of IL-8 mRNA by phorbol ester and changes the release of IL-8 from HL 60 cells: differential inhibition of induced expression of IL-8, TNF-alpha, IL-1 alpha, and IL-1 beta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Alkaloids; Arachidonic Acid; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gene Expression; HL-60 Cells; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases A; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Changes in prostaglandin synthesis and metabolism associated with labour, and the influence of dexamethasone, RU 486 and progesterone.
Topics: Amnion; Analysis of Variance; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Chorion; Culture Techniques; Dexamethasone; Dinoprost; Dinoprostone; Female; Hormone Antagonists; Humans; Indomethacin; Labor, Obstetric; Mifepristone; Pregnancy; Progesterone; Prostaglandins; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1995 |
Novel function of prostaglandins as inducers of gene expression of HGF and putative mediators of tissue regeneration.
Topics: Alprostadil; Animals; Blotting, Western; Bucladesine; Calcimycin; Cells, Cultured; CHO Cells; Cricetinae; Culture Media, Conditioned; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Epoprostenol; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Interleukin-1; Prostaglandin D2; Prostaglandins; Recombinant Proteins; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor beta | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Cell type specificity and protein kinase C dependency on the stimulation of prostaglandin E2 and prostaglandin F2 alpha production by oxytocin and platelet-activating factor in bovine endometrial cells.
Topics: Animals; Cattle; Cells, Cultured; Dinoprost; Dinoprostone; Endometrium; Female; Oxytocin; Platelet Activating Factor; Prostaglandins; Protein Kinase C; Stimulation, Chemical; Tachyphylaxis; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Regulation of heme oxygenase mRNA in mesangial cells: prostaglandin E2 negatively modulates interleukin-1-induced heme oxygenase-1 mRNA.
Topics: Animals; Base Sequence; Cells, Cultured; Colforsin; Dinoprostone; Gene Expression Regulation; Glomerular Mesangium; Heme Oxygenase (Decyclizing); Hot Temperature; Humans; Indomethacin; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Prostaglandin F2 alpha inhibits epidermal growth factor binding to cellular receptors on adipocyte precursors in primary culture.
Topics: Adipose Tissue; Animals; Cells, Cultured; Dinoprost; Dinoprostone; Epidermal Growth Factor; ErbB Receptors; Kinetics; Prostaglandin D2; Protein Kinase C; Rats; Stem Cells; Tetradecanoylphorbol Acetate | 1995 |
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera Toxin; Colforsin; Dinoprostone; Hypertension; Ions; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 1995 |
Differential effects of a steroidal antiestrogen, EM-139, on prostaglandin and cyclic adenosine 3',5'-monophosphate production in the circular and longitudinal layers of bovine myometrium.
Topics: Animals; Cattle; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Estradiol; Estrogen Antagonists; Female; Isoproterenol; Kinetics; Myometrium; Prostaglandins; Tetradecanoylphorbol Acetate | 1995 |
Isoflurane modulates phorbol myristate acetate-, prostaglandin D2-, and prostaglandin E2-induced alterations in hepatic flow and metabolism in the perfused liver in fasted rats.
Topics: Animals; Dinoprostone; Enzyme Activation; Fasting; Halothane; In Vitro Techniques; Isoflurane; Lactates; Lactic Acid; Liver; Liver Circulation; Male; Oxygen Consumption; Perfusion; Prostaglandin D2; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1994 |
Effects of an anti-inflammatory peptide (antiflammin 2) on cell influx, eicosanoid biosynthesis and oedema formation by arachidonic acid and tetradecanoyl phorbol dermal application.
Topics: Acetylglucosaminidase; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capillary Permeability; Dexamethasone; Dinoprostone; Ear Diseases; Edema; Eicosanoids; Indomethacin; Leukotriene B4; Male; Mice; Oligopeptides; Peptide Fragments; Peroxidase; Tetradecanoylphorbol Acetate | 1995 |
Activation mechanism of phospholipase D involved in the generation of lipid mediators in cultured Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acids; Cell Line; Cell-Free System; Choline; Deoxyglucose; Dinoprostone; Dogs; Eicosanoids; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Kidney; Lipid Metabolism; Oleic Acid; Oleic Acids; Phosphatidylcholines; Phospholipase D; Tetradecanoylphorbol Acetate | 1995 |
Divergent actions of prostaglandins-E2 and -F2 alpha on the regulation of insulin-like growth factor-binding protein-3 in luteinized granulosa cells.
Topics: 1-Methyl-3-isobutylxanthine; Analysis of Variance; Animals; Bucladesine; Carrier Proteins; Cells, Cultured; Cyclic AMP; Dinoprost; Dinoprostone; Female; Granulosa Cells; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor II; Progesterone; Swine; Tetradecanoylphorbol Acetate | 1993 |
Attenuated prostaglandin formation in peroxisomal-deficient human skin fibroblasts.
Topics: Arachidonic Acid; Cells, Cultured; Dinoprostone; Fibroblasts; Gene Expression; Humans; Hydrogen Peroxide; In Vitro Techniques; Microbodies; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Refsum Disease; RNA, Messenger; Tetradecanoylphorbol Acetate; Zellweger Syndrome | 1993 |
CGP 41251, a novel protein kinase inhibitor with in vitro selectivity for protein kinase C, strongly inhibits immunological activation of human skin mast cells and human basophils.
Topics: Alkaloids; Basophils; Dinoprostone; Female; Histamine Release; Humans; Leukotrienes; Mast Cells; Protein Kinase C; Receptors, IgE; Signal Transduction; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Dinoprostone; Gene Deletion; Gene Expression; Humans; Interleukin-2; Ionomycin; Kinetics; Mice; Phosphoprotein Phosphatases; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Activation; Glomerular Mesangium; Isoproterenol; Kidney Glomerulus; Male; Pertussis Toxin; Protein Kinase C; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.
Topics: Base Sequence; Cells, Cultured; Dinoprostone; Eicosanoids; Female; Fibroblasts; Humans; Immunoblotting; Interleukin-1; Intramolecular Oxidoreductases; Isomerases; Lipopolysaccharides; Lung; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Pulmonary Fibrosis; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of prostaglandin E2-responsive adenylyl cyclase in embryonal human kidney 293 cells by phorbol esters.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Cells, Cultured; Cyclic AMP; Dinoprostone; Embryo, Mammalian; Humans; Kidney; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1995 |
Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Carrageenan; Dinoprostone; Female; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Phagocytosis; Phenotype; Platelet Activating Factor; Spleen; Tetradecanoylphorbol Acetate | 1995 |
Bradykinin and Met-T-kinin-Leu stimulated PGE2 production by rat macrophage and fibroblast.
Topics: Animals; Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Fibroblasts; Macrophages; Rats; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Characterization of the signal transduction of prostaglandin E receptor EP1 subtype in cDNA-transfected Chinese hamster ovary cells.
Topics: Animals; CHO Cells; Cricetinae; Dinoprostone; Down-Regulation; Guanine Nucleotides; Mice; Phosphatidylinositols; Protein Kinase C; Receptors, Prostaglandin E; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Comparison of tumour promoter-induced prostaglandin E2 release in human and rat keratinocytes.
Topics: Acetates; Acetic Acid; Animals; Anthralin; Biological Transport; Carcinogens; Cell Survival; Cells, Cultured; Dinoprostone; Diterpenes; Humans; Keratinocytes; Kinetics; Mouth Mucosa; Neutral Red; Rats; Sodium Dodecyl Sulfate; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Autoregulation of inducible prostaglandin G/H synthase in osteoblastic cells by prostaglandins.
Topics: 3T3 Cells; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Blotting, Western; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; DNA, Complementary; Enzyme Induction; Mice; Nucleic Acid Hybridization; Osteoblasts; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Effect of retinoic acid on prostaglandin F2 alpha-induced prostaglandin E2 synthesis in osteoblast-like cells.
Topics: Cells, Cultured; Dinoprost; Dinoprostone; Humans; Melitten; Osteoblasts; Pertussis Toxin; Tetradecanoylphorbol Acetate; Tretinoin; Virulence Factors, Bordetella | 1994 |
Nitric oxide synthesis and its regulation by rabbit synoviocytes.
Topics: Alkaloids; Animals; Cell Line; Cells, Cultured; Cytokines; Dinoprostone; Fibroblasts; Free Radicals; Interferon-gamma; Interleukin-1; Metalloendopeptidases; Nitric Oxide; Platelet-Derived Growth Factor; Protein Kinase C; Rabbits; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1994 |
Modulation of phorbol ester-induced HL-60 differentiation by prostaglandin E2.
Topics: Carcinogenicity Tests; Carcinogens; Cell Differentiation; Cell Separation; Cell Transformation, Neoplastic; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Phagocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
The activation of protein kinase C prevents PGE2-induced inhibition of AVP-dependent cAMP accumulation in the rat outer medullary collecting tubule.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arginine Vasopressin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmolar Concentration; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Induction of asparagine synthetase by follicle-stimulating hormone in primary cultures of rat Sertoli cells.
Topics: Aging; Animals; Aspartate-Ammonia Ligase; Blotting, Northern; Blotting, Western; Brain; Bucladesine; Cells, Cultured; Culture Techniques; Dinoprostone; Enzyme Induction; Follicle Stimulating Hormone; Insulin; Kinetics; Liver; Male; Rats; Rats, Wistar; RNA, Messenger; Sertoli Cells; Testis; Testosterone; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Glycerol; Isoproterenol; Kinetics; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Release and steroidogenic actions of polyunsaturated fatty acids in the goldfish testis.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Goldfish; Indomethacin; Male; Prostaglandins E; Testis; Testosterone; Tetradecanoylphorbol Acetate | 1994 |
Effect of vitamin D3 on prostaglandin E2 synthesis in osteoblast-like cells.
Topics: 24,25-Dihydroxyvitamin D 3; Animals; Calcitriol; Cell Line; Cholecalciferol; Dinoprost; Dinoprostone; Enzyme Activation; Mice; Osteoblasts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Role of prostaglandin-mediated cyclic AMP formation in protein kinase C-dependent secretion of atrial natriuretic peptide in rat cardiomyocytes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Atrial Natriuretic Factor; Bucladesine; Cells, Cultured; Cyclic AMP; Diclofenac; Dinoprost; Dinoprostone; Epoprostenol; Heart; Heart Ventricles; Indomethacin; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Prostaglandins; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thionucleotides | 1994 |
Effect of glucocorticoid on prostaglandin F2 alpha-induced prostaglandin E2 synthesis in osteoblast-like cells: inhibition of phosphoinositide hydrolysis by phospholipase C as well as phospholipase A2.
Topics: Animals; Cells, Cultured; Dexamethasone; Dinoprost; Dinoprostone; Hydrolysis; Melitten; Mice; Osteoblasts; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Effect of arsenic exposure on alveolar macrophage function. I. Effect of soluble as(III) and as(V).
Topics: Animals; Arsenic Poisoning; Bronchoalveolar Lavage Fluid; Cells, Cultured; Dinoprostone; Macrophages, Alveolar; Male; Poisoning; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Inhibition of respiratory burst in macrophages by complement receptor blockade.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Dapsone; Dinoprostone; Eicosanoids; Indomethacin; Macrophage-1 Antigen; Macrophages, Peritoneal; Male; Oxygen Consumption; Rats; Rats, Wistar; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Anti-inflammatory action of orally active 5-lipoxygenase inhibitor TMK688.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase Inhibitors; Dermatitis, Contact; Dinoprostone; Dose-Response Relationship, Drug; Female; Leukotriene B4; Lipoxygenase Inhibitors; Mice; Piperidines; Tetradecanoylphorbol Acetate | 1994 |
Effects of prostaglandin E2 on Th0-type human T cell clones: modulation of functions of nuclear proteins involved in cytokine production.
Topics: Base Sequence; Calcimycin; CD3 Complex; Cell Line; Cyclic AMP; Cytokines; Dinoprostone; Humans; Interleukin-4; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1994 |
Phorbol myristate acetate stimulates osteoclast formation in 1 alpha,25-dihydroxyvitamin D3-primed mouse embryonic calvarial cells by a prostaglandin-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcitriol; Cell Differentiation; Dinoprostone; Drug Synergism; Embryo, Mammalian; In Vitro Techniques; Isoquinolines; Mice; Mice, Inbred ICR; Osteoclasts; Piperazines; Skull; Stem Cells; Tetradecanoylphorbol Acetate | 1994 |
Stimulation of enterocyte protein kinase C by laxatives in-vitro.
Topics: Animals; Cathartics; Dinoprostone; Fatty Acids; Female; In Vitro Techniques; Indicators and Reagents; Intestinal Mucosa; Protein Kinase C; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1993 |
Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation.
Topics: Calcimycin; Catechols; Cells, Cultured; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; Humans; Isoflavones; Keratinocytes; Kinetics; Nitriles; Protein-Tyrosine Kinases; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tyrphostins; Ultraviolet Rays | 1994 |
Transforming growth factor beta 1 augments mitogen-induced prostaglandin synthesis and expression of the TIS10/prostaglandin synthase 2 gene both in Swiss 3T3 cells and in murine embryo fibroblasts.
Topics: 3T3 Cells; Animals; Base Sequence; Cells, Cultured; Dexamethasone; Dinoprostone; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation, Enzymologic; Mice; Mice, Inbred BALB C; Mitogens; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Serum Albumin; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta | 1994 |
Altered leukotriene B4 levels by HL-60 cells after monocytic/macrophage differentiation.
Topics: Arachidonic Acids; Cell Differentiation; Cell Division; Cell Line; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Macrophages; Masoprocol; Monocytes; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1993 |
Production of prostanoids by Lewis rat Schwann cells in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Half-Life; Interferon-gamma; Rats; Rats, Inbred Lew; Schwann Cells; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Tumor Necrosis Factor-alpha | 1994 |
Role of carbonic anhydrase in basal and stimulated bicarbonate secretion by the guinea pig duodenum.
Topics: Acetazolamide; Animals; Bicarbonates; Bucladesine; Carbachol; Carbonic Anhydrases; Dibutyryl Cyclic GMP; Dinoprostone; Duodenum; Glucagon; Guinea Pigs; Male; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1994 |
IL-1 beta amplifies bradykinin-induced prostaglandin E2 production via a phospholipase D-linked mechanism.
Topics: Bradykinin; Cells, Cultured; Diglycerides; Dinoprostone; Drug Synergism; Humans; Interleukin-1; Phospholipase D; Synovial Membrane; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1994 |
Regulation of prostaglandin endoperoxide H synthase by glucocorticoids and activators of protein kinase C in the human amnion.
Topics: Amnion; Culture Techniques; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glucocorticoids; Humans; Hydrocortisone; Mifepristone; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arachidonic Acid; Base Sequence; Cell Line; Cells, Cultured; Dinoprostone; Embryo, Mammalian; Fibroblasts; Gene Expression; Immune Sera; Lipopolysaccharides; Macrophages; Mice; Molecular Sequence Data; Oligonucleotides, Antisense; Peptides; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Transfection | 1994 |
A novel synergistic stimulation of Swiss 3T3 cells by extracellular ATP and mitogens with opposite effects on cAMP levels.
Topics: 3T3 Cells; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arachidonic Acid; Cell Division; Cell Nucleus; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; DNA; Drug Synergism; Epidermal Growth Factor; Kinetics; Lysophospholipids; Mice; Mitogens; Phosphatidic Acids; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
Actions of interleukin-2 on chorio-decidual prostaglandin biosynthesis.
Topics: Cells, Cultured; Chorion; Decidua; Dinoprostone; Epidermal Growth Factor; Female; Humans; Interleukin-1; Interleukin-2; Ionomycin; Tetradecanoylphorbol Acetate | 1993 |
A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages.
Topics: Alkaloids; Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Eicosanoids; Fatty Acids; Isoenzymes; Kinetics; Leukotriene C4; Macrophages, Peritoneal; Mice; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.
Topics: Animals; Cell Line; Colforsin; Culture Media; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Dinoprostone; DNA; Enzyme Induction; Hydrocortisone; Kinetics; Mice; Osteoblasts; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1993 |
Tumour necrosis factor-alpha enhances cAMP-induced programmed cell death in mouse thymocytes.
Topics: 2-Chloroadenosine; Animals; Apoptosis; Calcimycin; Cell Survival; Cells, Cultured; Cyclic AMP; Dinoprostone; DNA Damage; Humans; Interferon-gamma; Isoproterenol; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Nucleosomes; Recombinant Proteins; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Actions of interleukin-4 on prostaglandin biosynthesis at the chorion-decidual interface.
Topics: Cells, Cultured; Chorion; Decidua; Dinoprostone; Female; Humans; Interleukin-4; Ionomycin; Pregnancy; Tetradecanoylphorbol Acetate | 1993 |
Involvement of protein kinase C in the interleukin 1 alpha-induced gene expression of matrix metalloproteinases and tissue inhibitor-1 of metalloproteinases (TIMP-1) in human uterine cervical fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cells, Cultured; Collagen; Dinoprostone; Down-Regulation; Extracellular Matrix; Female; Fibroblasts; Gene Expression Regulation; Glycoproteins; Guinea Pigs; Humans; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Precursors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases; Uterus | 1993 |
Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Eicosanoids; Female; Indoles; Inflammation; Maleimides; Mice; Neutrophils; Peroxidase; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1993 |
Glycogenolytic and antiglycogenolytic prostaglandin E2 actions in rat hepatocytes are mediated via different signalling pathways.
Topics: Animals; Cells, Cultured; Dinoprostone; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Liver; Male; Pertussis Toxin; Phosphorylases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6.
Topics: Antigens, CD; Base Sequence; Cell Adhesion; Cell Differentiation; Cell Line; Dinoprostone; Humans; Lipopolysaccharides; Molecular Sequence Data; Monocytes; Phagocytosis; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
12-O-tetradecanoylphorbol-13-acetate and the induction of prostaglandin E2 generation by human keratinocytes: a re-evaluation.
Topics: Cells, Cultured; Dinoprostone; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Keratinocytes; Sensitivity and Specificity; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
Tumor necrosis factor alpha stimulates amnion prostaglandin biosynthesis primarily via an action on fatty acid cyclooxygenase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amnion; Arachidonic Acid; Aspirin; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Isoquinolines; Piperazines; Pregnancy; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Mechanism of endothelin activation of phospholipase A2 in rat renal medullary interstitial cells.
Topics: Animals; Calcium; Dinoprostone; Endothelins; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Kidney Medulla; Nickel; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1994 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Modulation of phorbol ester-associated events in epidermal cells by linoleate and arachidonate.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Dinoprostone; Epidermis; Kinetics; Linoleic Acid; Linoleic Acids; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells.
Topics: Animals; Blotting, Southern; Blotting, Western; Cells, Cultured; Dexamethasone; Dinoprostone; Epidermal Growth Factor; Epithelium; Gene Expression; Genes; In Vitro Techniques; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Trachea | 1993 |
Regulation of astrocyte proliferation by prostaglandin E2 and the alpha subtype of protein kinase C.
Topics: Alkaloids; Animals; Astrocytes; Cell Division; Cells, Cultured; Dinoprostone; Enzyme Activation; Indomethacin; Lipopolysaccharides; Mice; Mice, Inbred ICR; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Stimulation of cultured amnion cell prostaglandin endoperoxide H synthase activity by glucocorticoids and phorbol ester.
Topics: Amnion; Analysis of Variance; Arachidonic Acid; Cells, Cultured; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Regression Analysis; Tetradecanoylphorbol Acetate | 1993 |
Up-regulation of oxytocin receptors in rabbit amnion by adenosine 3',5'-monophosphate.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amnion; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; Drug Synergism; Female; Isoquinolines; Oxytocin; Piperazines; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Receptors, Angiotensin; Receptors, Oxytocin; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Angiotensin-II stimulates an increase in cAMP and expression of 17 alpha-hydroxylase cytochrome P450 in fetal bovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Bucladesine; Cattle; Cells, Cultured; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Fetus; Kinetics; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate | 1993 |
Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+.
Topics: Amiloride; Animals; Anti-Infective Agents; Biphenyl Compounds; Calcimycin; Calcium; Carrier Proteins; Cell Survival; Cells, Cultured; Dinoprostone; Hydrogen-Ion Concentration; Hypoxia; Kupffer Cells; Leukotriene B4; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Oxygen; Prostaglandin D2; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1993 |
Effect of PGE2 on thymocyte proliferation induced by Con A or IL-4 + PMA.
Topics: Animals; CD4 Antigens; CD8 Antigens; Cell Count; Concanavalin A; Cyclic AMP; Dinoprostone; In Vitro Techniques; Interleukin-4; Kinetics; Lymphocyte Activation; Male; Mice; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 1993 |
Phosphorylation and activation of the arachidonate-mobilizing phospholipase A2 in macrophages in response to bacteria.
Topics: Animals; Arachidonic Acids; Bacterial Physiological Phenomena; Cells, Cultured; Dinoprostone; Enzyme Activation; Ethers, Cyclic; Female; Gardnerella vaginalis; Macrophages; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Phorbol ester, prostaglandin E2, forskolin and okadaic acid differentially modulate interleukin-4-versus interleukin-2-dependent immunoglobulin induction in human cellular models, in contrast to other selected modifiers of cellular activation.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Cells, Cultured; Colforsin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Interleukin-2; Interleukin-4; Interleukins; Lymphocyte Activation; Okadaic Acid; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase A activators inhibit agonist induced prostaglandin production in human amnion.
Topics: Adenylyl Cyclases; Amnion; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Female; Fetus; Humans; In Vitro Techniques; Isoproterenol; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cholera Toxin; Colforsin; Consensus Sequence; Cyclic AMP; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Phosphorylation; Piperazines; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Interleukin-8 production by the human cervix.
Topics: Abortifacient Agents, Nonsteroidal; Alprostadil; Analysis of Variance; Cervix Uteri; Culture Techniques; Dimethylformamide; Dinoprostone; Ethers, Cyclic; Female; Humans; Interleukin-8; Lipopolysaccharides; Menopause; Okadaic Acid; Phosphoprotein Phosphatases; Pregnancy; Progesterone; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1).
Topics: Cell Differentiation; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Induction; Humans; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Tumor necrosis factor-alpha potentiates phospholipase A2-stimulated release and metabolism of arachidonic acid in cultured intestinal epithelial cells (INT 407).
Topics: Arachidonic Acid; Calcimycin; Cell Line; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; Intestinal Mucosa; Lipid Metabolism; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1993 |
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.
Topics: Animals; Arachidonic Acid; Bacteriophage lambda; Base Sequence; Dinoprostone; Female; Genetic Vectors; Genotype; Homozygote; Kidney; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mortality; Otitis Externa; Peritoneum; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1995 |
Metabolic alterations of zinc and prostaglandins in both human and animal colonic tumor cells.
Topics: Animals; Azoxymethane; Base Sequence; Carcinogens; Colonic Neoplasms; Dinoprost; Dinoprostone; DNA, Neoplasm; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc | 1995 |
Interleukin-1 beta induces expression of cyclooxygenase-2 mRNA in human gingival fibroblasts.
Topics: Base Sequence; Cells, Cultured; Child; Dexamethasone; Dinoprostone; Fibroblasts; Gingiva; Humans; Interleukin-1; Isoenzymes; Molecular Probes; Molecular Sequence Data; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Interleukin-4 gene expression in activated human T lymphocytes is regulated by the cyclic adenosine monophosphate-dependent signaling pathway.
Topics: Antibodies, Monoclonal; Bucladesine; Calcimycin; CD28 Antigens; Concanavalin A; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-4; Interleukins; Lymphocyte Activation; Muromonab-CD3; Recombinant Proteins; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Independent down-regulation of EP2 and EP3 subtypes of the prostaglandin E2 receptors on U937 human monocytic cells.
Topics: Base Sequence; Blotting, Western; Cell Movement; Cyclic AMP; Dinoprostone; Down-Regulation; Humans; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Protein Kinase C; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Effect of prostaglandin E2 on phospholipase D activity in osteoblast-like MC3T3-E1 cells.
Topics: 3T3 Cells; Animals; Chelating Agents; Choline; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; GTP-Binding Proteins; Inositol Phosphates; Mice; Osteoblasts; Phosphatidylcholines; Phospholipase D; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1995 |
Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Kinetics; Osteoblasts; Parathyroid Hormone; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Signal Transduction; Skull; Tetradecanoylphorbol Acetate | 1995 |
CD40 ligand is expressed and functional on activated neonatal T cells.
Topics: Adult; Antibodies, Monoclonal; Base Sequence; CD3 Complex; CD40 Antigens; CD40 Ligand; Cyclosporine; Dinoprostone; Fetal Blood; Humans; Infant, Newborn; Ionomycin; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Molecular Sequence Data; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3.
Topics: Blotting, Western; Calcitriol; Carcinogens; Cell Differentiation; Cell Division; Cytosol; Dinoprostone; Enzyme Activation; Humans; Isoenzymes; Leukemia, Monocytic, Acute; Lipopolysaccharide Receptors; Macrophage-1 Antigen; Phagocytosis; Phospholipases A; Phospholipases A2; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-1 alpha activates an NF-kappaB-like factor in osteoclast-like cells.
Topics: Animals; Base Sequence; Bone Marrow; Bone Marrow Cells; Calcitonin; Calcitriol; Cell Nucleus; Coculture Techniques; Dinoprostone; DNA; DNA-Binding Proteins; Femur; Interleukin-1; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Osteoclasts; Skull; Tetradecanoylphorbol Acetate; Tibia | 1996 |
Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.
Topics: Alkaline Phosphatase; Bucladesine; Clone Cells; Colforsin; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; Female; Humans; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Marine Toxins; NFATC Transcription Factors; Nuclear Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Protein Phosphatase 1; Recombinant Proteins; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers.
Topics: Aggrecans; Alprostadil; Animals; Bucladesine; Calcium; Cartilage; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; DNA; Extracellular Matrix Proteins; Lectins, C-Type; Prostaglandins; Protein Kinase C; Proteoglycans; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1996 |
Activation of the cAMP-dependent signaling pathway downregulates the expression of interleukin-3 and granulocyte-macrophage colony-stimulating factor in activated human T lymphocytes.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Cells, Cultured; Concanavalin A; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Synergism; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Interleukin-3; Isoproterenol; Lymphocyte Activation; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Phospholipase D-derived products in the regulation of 12-O-tetradecanoylphorbol-13-acetate-stimulated prostaglandin synthesis in madin-darby canine kidney cells.
Topics: Animals; Calcimycin; Cell Line; Diglycerides; Dinoprostone; Dogs; Enzyme Activation; Enzyme Induction; Ethanol; Glycerophospholipids; Kidney; Kinetics; Phosphatidic Acids; Phospholipase D; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-1beta activates protein kinase C zeta in renal mesangial cells. Potential role in prostaglandin E2 up-regulation.
Topics: Alkaloids; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cytosol; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Naphthalenes; NF-kappa B; Oligonucleotide Probes; Oligonucleotides, Antisense; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1996 |
Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.
Topics: Acetylglucosamine; Animals; Bile Acids and Salts; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Dogs; Edetic Acid; Enzyme Activation; Epithelium; Gallbladder; Ionomycin; Kinetics; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Regulation of prostaglandin synthesis in Madin Darby canine kidney cells: role of prostaglandin G/H synthase and secreted phospholipase A2.
Topics: Animals; Base Sequence; Cell Line; Dibenzoxepins; Dinoprostone; DNA Primers; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Enzyme Inhibitors; Kidney; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1996 |
Selective inhibition of polymorphonuclear leukocytes by immunosuppressive concentration of prostaglandin E2.
Topics: Dinoprostone; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Immunosuppressive Agents; Macrophage-1 Antigen; Neutrophils; Receptors, IgG; Temperature; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Dinoprostone; Enzyme Activation; Loop of Henle; Male; Pertussis Toxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
Proliferation-dependent changes in arachidonic acid mobilization from phospholipids of 3T6 fibroblasts.
Topics: Animals; Arachidonic Acid; Bradykinin; Calcimycin; Cell Division; Cell Line; Culture Media; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phospholipids; Phosphoric Monoester Hydrolases; Tetradecanoylphorbol Acetate | 1996 |
Modification of cultured Madin-Darby canine kidney cells with dietary unsaturated fatty acids and regulation of arachidonate cascade reaction.
Topics: Animals; Arachidonic Acid; Blotting, Western; Calcimycin; Cell Division; Cell Line; Cell Survival; Culture Media; Dinoprostone; Dogs; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Fatty Acids, Unsaturated; Ionophores; Kidney; Phospholipids; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1996 |
Regulation of arachidonic acid metabolism, aromatase activity and growth in human breast cancer cells by interleukin-1beta and phorbol ester: dissociation of a mediatory role for prostaglandin E2 in the autocrine control of cell function.
Topics: Arachidonic Acid; Aromatase; Breast Neoplasms; Cell Division; Dexamethasone; Dinoprostone; Enzyme Induction; Humans; Indomethacin; Interleukin-1; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Prostaglandin E2 induces Egr-1 mRNA in MC3T3-E1 osteoblastic cells by a protein kinase C-dependent pathway.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Northern; Bone and Bones; Cycloheximide; Dinoprostone; DNA-Binding Proteins; Down-Regulation; Early Growth Response Protein 1; Enzyme Inhibitors; Immediate-Early Proteins; Mice; Osteoblasts; Phenanthridines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1996 |
Cyclosporin A inhibits prostaglandin E2 production by fetal amnion cells in response to various stimuli.
Topics: Amnion; Cells, Cultured; Cyclosporine; Dinoprostone; Female; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-1; Ionomycin; Pregnancy; Tetradecanoylphorbol Acetate | 1996 |
Synthesis and release of phosphatidylcholine by isolated porcine gastric mucous cells in primary culture.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Separation; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Indomethacin; Phosphatidylcholines; Swine; Tetradecanoylphorbol Acetate | 1996 |
Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines.
Topics: Blotting, Northern; Breast Neoplasms; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Female; Humans; Isoenzymes; Membrane Proteins; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Anti-inflammatory properties of docosahexaenoic and eicosapentaenoic acids in phorbol-ester-induced mouse ear inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Dermatitis; Dinoprostone; Disease Models, Animal; Docosahexaenoic Acids; Ear, External; Edema; Eicosapentaenoic Acid; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Neutrophils; Peroxidase; Steroids; Tetradecanoylphorbol Acetate | 1996 |
Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Calcimycin; Calcium; Coculture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Erythrocytes; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Ionophores; Leukotriene B4; Lipoxygenase; Lung Neoplasms; Neutrophils; Phospholipases A; Phospholipases A2; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Hepatocyte growth factor is a paracrine regulator of rat prostate epithelial growth.
Topics: Animals; Base Sequence; Bucladesine; Cell Division; Cells, Cultured; Dinoprostone; DNA; DNA Primers; Epidermal Growth Factor; Epithelial Cells; Epithelium; Hepatocyte Growth Factor; Humans; Male; Polymerase Chain Reaction; Prostate; Proto-Oncogene Proteins c-met; Rats; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Human neutrophil secondary granule exocytosis is independent of protein kinase activation and is modified by calmodulin activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Bucladesine; Calmodulin; Cytoplasmic Granules; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Genistein; Humans; Isoflavones; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vanadates | 1996 |
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
Topics: Adipose Tissue; Aromatase; Breast Neoplasms; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Stromal Cells; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase C plays a key role in the cross-talk between intracellular signalings via prostanoid receptors in a megakaryoblastic cell line, MEG-01s.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Hematopoietic Stem Cells; Humans; Iloprost; Ionomycin; Megakaryocytes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Prostaglandin; Receptors, Thrombin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1996 |
Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Diethylhexyl Phthalate; Dinoprostone; Enzyme Induction; Indomethacin; Isoenzymes; Liver; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrimidines; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Induction of prostaglandin H synthase-2 and tumor necrosis factor-alpha in human amnionic WISH cells by various stimuli occurs through distinct intracellular mechanisms.
Topics: Amnion; Base Sequence; Blotting, Northern; Cell Line; Cyclooxygenase 2; Dinoprostone; DNA Primers; Enzyme Induction; Female; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoenzymes; Kinetics; Membrane Proteins; Models, Biological; Molecular Sequence Data; Okadaic Acid; Polymerase Chain Reaction; Pregnancy; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1997 |
Retinoids suppress phorbol ester-mediated induction of cyclooxygenase-2.
Topics: Anticarcinogenic Agents; Biotransformation; Carcinoma, Squamous Cell; Cyclooxygenase 2; Dinoprostone; Diterpenes; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Isotretinoin; Membrane Proteins; Mouth Neoplasms; Neoplasm Proteins; Peroxidases; Prostaglandin-Endoperoxide Synthases; Retinyl Esters; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Vitamin A | 1997 |
Protein kinase C-independent activation of a novel nonspecific phospholipase C pathway by phorbol myristate acetate releases arachidonic acid for prostaglandin synthesis in MC3T3-E1 osteoblasts.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Line; Cyclohexanones; Diglycerides; Dinoprostone; Down-Regulation; Eicosanoids; Enzyme Activation; Lipoprotein Lipase; Membrane Lipids; Mice; Osteoblasts; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Phospholipids; Prostaglandins; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1997 |
Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages.
Topics: Animals; Antirheumatic Agents; Arachidonic Acid; Auranofin; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; In Vitro Techniques; Ionophores; Isoenzymes; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Transcriptional regulation of prostaglandin-H synthase-2 gene in human trophoblasts.
Topics: Aspirin; Blotting, Northern; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-1; Placenta; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Tetradecanoylphorbol Acetate; Transfection; Trophoblasts | 1997 |
Formation of eicosanoids during differentiation of THP-1 cells.
Topics: Calcimycin; Cell Differentiation; Cholecalciferol; Dinoprostone; Eicosanoids; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Leukemia, Monocytic, Acute; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage-1 Antigen; Neoplasm Proteins; Phagocytosis; Phospholipases A; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Topics: Becaplermin; Calcimycin; Colforsin; Dinoprostone; Drug Interactions; Gene Expression; Humans; Interleukin-1; Interleukin-6; Osteosarcoma; Plasmids; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins c-sis; Recombinant Fusion Proteins; Teriparatide; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
PGE2-mediated cytoprotection in renal epithelial cells: evidence for a pharmacologically distinct receptor.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Cytoprotection; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Glutathione; Hydroquinones; Kidney; LLC-PK1 Cells; Protein Kinase C; Receptors, Prostaglandin E; Swine; Tetradecanoylphorbol Acetate | 1997 |
Effects of quercetin on epithelial chloride secretion.
Topics: Carbachol; Cell Line; Chlorides; Colon; Dinoprostone; Electric Conductivity; Epithelial Cells; Humans; Protein Kinase C; Quercetin; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1997 |
Bradykinin stimulates cAMP synthesis via mitogen-activated protein kinase-dependent regulation of cytosolic phospholipase A2 and prostaglandin E2 release in airway smooth muscle.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cytosol; Dinoprostone; Down-Regulation; Drug Interactions; Flavonoids; Guinea Pigs; Indoles; Indomethacin; Maleimides; Muscle, Smooth; Phospholipases A; Phospholipases A2; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trachea | 1997 |
Fenretinide inhibits phorbol ester-induced cyclooxygenase-2 expression in human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fenretinide; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capsaicin; Collagenases; Curcumin; Dinoprostone; Hyaluronoglucosaminidase; Leukotriene B4; Leukotriene C4; Lysosomes; Macrophages, Peritoneal; Male; Membrane Lipids; Pancreatic Elastase; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Prostaglandin E2 stimulates sodium-dependent phosphate transport in osteoblastic cells via a protein kinase C-mediated pathway.
Topics: Androstadienes; Animals; Biological Transport; Cells, Cultured; Dinoprostone; DNA; Genistein; Indomethacin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Osteoblasts; Phosphates; Protein Kinase C; Rats; Sodium; Tetradecanoylphorbol Acetate; Wortmannin | 1998 |
ATP and UTP activate calcium-mobilizing P2U-like receptors and act synergistically with interleukin-1 to stimulate prostaglandin E2 release from human rheumatoid synovial cells.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Buffers; Calcium; Dinoprostone; Drug Synergism; Humans; Interleukin-1; Middle Aged; Purinergic Agonists; Receptors, Purinergic; Synovial Membrane; Tetradecanoylphorbol Acetate; Thapsigargin; Uridine Triphosphate | 1998 |
Alternate signaling pathways selectively regulate binding of insulin-like growth factor I and II on fetal rat bone cells.
Topics: Animals; Binding Sites; Binding, Competitive; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activation; Fetus; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Osteoblasts; Parietal Bone; Prostaglandins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, IGF Type 2; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Prostaglandin E2 differentially modulates IL-5 gene expression in activated human T lymphocytes depending on the costimulatory signal.
Topics: Bucladesine; Concanavalin A; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-5; Lymphocyte Activation; Mitogens; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; RNA, Messenger; Signal Transduction; Stimulation, Chemical; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 1998 |
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Genes, Reporter; Hydroxycholesterols; Indoles; Isoquinolines; Liver X Receptors; Maleimides; Orphan Nuclear Receptors; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Prostaglandin E2 induces vascular endothelial growth factor and basic fibroblast growth factor mRNA expression in cultured rat Müller cells.
Topics: Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gene Expression; Lymphokines; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Retina; RNA, Messenger; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Evaluation of the cutaneous anti-inflammatory activity of azaspiranes.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Line; Cyclooxygenase 1; Dermatitis, Contact; Dinoprostone; Ear; Edema; Humans; Immunosuppressive Agents; Isoenzymes; Leukotriene B4; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Monocytes; NF-kappa B; Peroxidase; Piperidines; Prostaglandin-Endoperoxide Synthases; Spiro Compounds; Tetradecanoylphorbol Acetate | 1998 |
Regulation of eicosanoid synthesis in liver macrophages.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Dinoprostone; Eicosanoids; Inositol Phosphates; Kinetics; Kupffer Cells; Models, Biological; Sodium Fluoride; Tetradecanoylphorbol Acetate; Zymosan | 1997 |
Induction of prostaglandin endoperoxide synthase-1 (COX-1) in a human promonocytic cell line by treatment with the differentiating agent TPA.
Topics: Calcium; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Enzyme Induction; Humans; Isoenzymes; Magnesium; Membrane Proteins; Monocytes; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Effect of PGE2 on the cell surface molecule expression in PMA treated thymocytes.
Topics: Animals; Antigens, CD; Bucladesine; CD3 Complex; CD4 Antigens; CD8 Antigens; Cells, Cultured; Cyclic GMP; Dinoprost; Dinoprostone; Female; Flow Cytometry; Mice; Mice, Inbred C57BL; Prostaglandin D2; Surface Properties; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1998 |
Arachidonic acid and human bone marrow stromal cells.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Dinoprostone; Fatty Acids; Humans; Interleukin-6; Leukotriene B4; Lipid Metabolism; Phospholipids; Stromal Cells; Tetradecanoylphorbol Acetate; Tritium; Tumor Necrosis Factor-alpha | 1998 |
Regulation of a common, low-affinity binding site for primary prostanoids on bovine aortic endothelial cells.
Topics: Animals; Aorta, Thoracic; Binding Sites; Bucladesine; Carcinogens; Cattle; Cells, Cultured; Cyclic AMP; Cytosol; Digitonin; Dinoprost; Dinoprostone; Endothelium, Vascular; Indicators and Reagents; Oxytocics; Prostaglandins; Protein Binding; Sodium Chloride; Solutions; Tetradecanoylphorbol Acetate; Time Factors; Tritium | 1998 |
Differential effects of protein kinase C agonists on prostaglandin production and growth in human breast cancer cells.
Topics: Antineoplastic Agents; Arachidonic Acid; Breast Neoplasms; Bryostatins; Cell Division; Dinoprostone; Enzyme Activation; Female; Humans; Lactones; Macrolides; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Conjugated linoleic acid reduces arachidonic acid content and PGE2 synthesis in murine keratinocytes.
Topics: Animals; Arachidonic Acid; Cell Line; Dinoprostone; Keratinocytes; Linoleic Acid; Mice; Tetradecanoylphorbol Acetate | 1998 |
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Colforsin; Cycloheximide; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Osteoblasts; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell.
Topics: Arachidonic Acid; Calcimycin; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Dinoprostone; Humans; Ionophores; Monocytes; Prostaglandins; Tetradecanoylphorbol Acetate; Thromboxane B2; Tretinoin | 1998 |
Phorbol ester-induced production of prostaglandin E2 from phosphatidylcholine through the activation of phospholipase D in UMR-106 cells.
Topics: Animals; Arachidonic Acid; Cell Line; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Lipoprotein Lipase; Myristic Acid; Osteoblasts; Phosphatidate Phosphatase; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Production of parathyroid hormone-related peptide by synovial fibroblasts in human osteoarthritis.
Topics: Cells, Cultured; Cytokines; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Kinetics; Osteoarthritis; Parathyroid Hormone-Related Protein; Polymerase Chain Reaction; Protein Biosynthesis; Proteins; Recombinant Proteins; Synovial Membrane; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1998 |
Prostaglandin E2 stimulates IL-8 gene expression in human colonic epithelial cells by a posttranscriptional mechanism.
Topics: Adenocarcinoma; Bucladesine; Colforsin; Colon; Colonic Neoplasms; Cyclic AMP; Dexamethasone; Dinoprostone; Dose-Response Relationship, Immunologic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Intracellular Fluid; Neoplasm Proteins; Protein Processing, Post-Translational; Receptors, Prostaglandin E; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
In vivo and in vitro antiinflammatory activity of saikosaponins.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Sequence; Cell Survival; Cells, Cultured; Dinoprostone; Ear, External; Edema; Female; Humans; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Molecular Sequence Data; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins; Tetradecanoylphorbol Acetate | 1998 |
Localization of prostaglandin H synthase isoenzymes in murine epidermal tumors: suppression of skin tumor promotion by inhibition of prostaglandin H synthase-2.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Epidermis; Female; Immunohistochemistry; Isoenzymes; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Interleukin-1alpha and tumor necrosis factor alpha synergistically stimulate prostaglandin E2-dependent production of interleukin-11 in rheumatoid synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indoles; Interleukin-1; Interleukin-11; Isoquinolines; Maleimides; Protein Kinase C; Signal Transduction; Sulfonamides; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Interference of myrtol standardized with inflammatory and allergic mediators.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Basophils; Cattle; Cyclohexanols; Dinoprostone; Drug Combinations; Drug Interactions; Eosinophils; Eucalyptol; Female; Guinea Pigs; Humans; Hyperemia; In Vitro Techniques; Inflammation; Leukemia, Basophilic, Acute; Leukotriene C4; Leukotriene D4; Leukotriene E4; Male; Mammary Glands, Animal; Menthol; Mice; Monoterpenes; Mucous Membrane; Muscle Contraction; Muscle, Smooth; Rats; Terpenes; Tetradecanoylphorbol Acetate; Trachea; Tumor Cells, Cultured | 1998 |
Hormone-stimulated Ca2+ reabsorption in rabbit kidney cortical collecting system is cAMP-independent and involves a phorbol ester-insensitive PKC isotype.
Topics: Adenosine; Animals; Arginine Vasopressin; Calcium; Culture Techniques; Cyclic AMP; Dideoxyadenosine; Dinoprostone; Hormones; Intracellular Fluid; Ion Transport; Isoenzymes; Kidney Cortex; Kidney Tubules, Collecting; Parathyroid Hormone; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1999 |
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Down-regulation of oxytocin-induced cyclooxygenase-2 and prostaglandin F synthase expression by interferon-tau in bovine endometrial cells.
Topics: Animals; Blotting, Northern; Cattle; Cells, Cultured; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Estrus; Female; Gene Expression Regulation, Enzymologic; Hydroxyprostaglandin Dehydrogenases; Interferon Type I; Isoenzymes; Oxytocin; Pregnancy Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate | 1999 |
Gadolinium blocks rat Kupffer cell calcium channels: relevance to calcium-dependent prostaglandin E2 synthesis and septic mortality.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dinoprostone; Gadolinium; Infections; Ionomycin; Ionophores; Kupffer Cells; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Mechanically induced c-fos expression is mediated by cAMP in MC3T3-E1 osteoblasts.
Topics: Animals; Cell Line; Centrifugation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Mice; Osteoblasts; Polymerase Chain Reaction; Proto-Oncogene Proteins c-fos; RNA, Messenger; Signal Transduction; Stress, Mechanical; Tetradecanoylphorbol Acetate | 1999 |
Inhibition by auranofin of the production of prostaglandin E2 and nitric oxide in rat peritoneal macrophages.
Topics: Animals; Antirheumatic Agents; Auranofin; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Indomethacin; Isoenzymes; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1999 |
Regulation of human airway mucins by acrolein and inflammatory mediators.
Topics: Acrolein; Carcinoma, Mucoepidermoid; Dinoprostone; Gene Expression Regulation; Humans; Hydroxyeicosatetraenoic Acids; Inflammation; Kinetics; Lung Neoplasms; Mucin 5AC; Mucin-5B; Mucins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Homologous and heterologous ligands downregulate follicle-stimulating hormone receptor mRNA in porcine granulosa cells.
Topics: Animals; Bucladesine; Cattle; Cells, Cultured; Cytochrome P-450 Enzyme System; Dinoprostone; Down-Regulation; Epidermal Growth Factor; Female; Follicle Stimulating Hormone; Granulosa Cells; Ligands; Luteinizing Hormone; Progesterone; Receptors, FSH; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate | 1999 |
Prostaglandin-endoperoxide H synthase-2 expression in human thyroid epithelium. Evidence for constitutive expression in vivo and in cultured KAT-50 cells.
Topics: Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Gene Expression Regulation; Genes, Reporter; Humans; Immunohistochemistry; Interleukin-1; Isoenzymes; Membrane Proteins; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Receptors, Interleukin-1; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Thyroid Gland; Transfection | 1999 |
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
Differential effect of TPA on PGE2 and cicaprost-induced cAMP synthesis in UMR-106 cells.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Inhibition by tectorigenin and tectoridin of prostaglandin E2 production and cyclooxygenase-2 induction in rat peritoneal macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drugs, Chinese Herbal; Enzyme Induction; Isoenzymes; Isoflavones; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1999 |
Effect of dietary conjugated linoleic acid on phorbol ester-induced PGE2 production and hyperplasia in mouse epidermis.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Capillary Permeability; Dietary Fats; Dinoprostone; DNA Primers; Dose-Response Relationship, Drug; Epidermis; Female; Genes, myc; Hyperplasia; Linoleic Acid; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Immunosuppression in hamsters with progressive visceral leishmaniasis: an evaluation of the role of nitric oxide toward impairment of the lymphoproliferative response.
Topics: Animals; Antigens, Protozoan; Concanavalin A; Cricetinae; Dinoprostone; Immune Tolerance; Leishmania donovani; Leishmaniasis, Visceral; Leukocytes, Mononuclear; Lymphocyte Activation; Macrophages; Mesocricetus; Nitric Oxide; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
Prostaglandin E2 regulates vitamin D receptor expression, vitamin D-24-hydroxylase activity and cell proliferation in an adherent human myeloid leukemia cell line (Ad-HL60).
Topics: 24,25-Dihydroxyvitamin D 3; Antigens, CD; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Dinoprostone; Flow Cytometry; HL-60 Cells; Humans; Phenotype; Receptors, Calcitriol; Steroid Hydroxylases; Tetradecanoylphorbol Acetate; Vitamin D3 24-Hydroxylase | 1999 |
Induction of prostanoid, nitric oxide, and cytokine formation in rat bone marrow derived macrophages by activin A.
Topics: Activins; Animals; Bone Marrow Cells; Cyclooxygenase 2; Cytokines; Dinoprostone; Inhibins; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1999 |
Cyclooxygenase-2 expression and function in the medullary thick ascending limb.
Topics: Animals; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Isoenzymes; Loop of Henle; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cells.
Topics: Amnion; Arachidonic Acid; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Ethanol; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Kinetics; Membrane Proteins; Naphthalenes; Nitrobenzenes; Pancreatitis-Associated Proteins; Phosphatidate Phosphatase; Phosphodiesterase Inhibitors; Propranolol; Prostaglandin-Endoperoxide Synthases; Pyrones; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Thromboxane A2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cell Movement; Cells, Cultured; Cornea; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelium, Vascular; Fatty Acids, Unsaturated; Fibroblast Growth Factor 2; Fibroblast Growth Factors; Humans; Hydrazines; Isoenzymes; Membrane Proteins; Mice; Mice, Inbred C57BL; Microcirculation; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Renal Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1999 |
Synovial PMN show a coordinated up-regulation of CD66 molecules.
Topics: Adult; Aged; Alprostadil; Antigens, CD; Antigens, Differentiation; Arthritis; Arthritis, Psoriatic; Arthritis, Reactive; Arthritis, Rheumatoid; CD59 Antigens; Cell Adhesion Molecules; Dinoprostone; Female; Flow Cytometry; Gene Expression Regulation; Glycosylphosphatidylinositols; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Isoforms; Receptors, IgG; Synovial Fluid; Tetradecanoylphorbol Acetate | 1999 |
Hormone-stimulated Ca2+ transport in rabbit kidney: multiple sites of inhibition by exogenous ATP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Triphosphate; Alkaloids; Animals; Arginine Vasopressin; Benzophenanthridines; Calcium; Cells, Cultured; Cyclic AMP; Deamino Arginine Vasopressin; Dinoprostone; Enzyme Inhibitors; Indomethacin; Kidney Cortex; Kidney Tubules; Kidney Tubules, Collecting; Models, Biological; Parathyroid Hormone; Phenanthridines; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rabbits; Tetradecanoylphorbol Acetate | 1999 |
Protein kinase C activation reduces microglial cyclic AMP response to prostaglandin E2 by interfering with EP2 receptors.
Topics: Animals; Cells, Cultured; Cyclic AMP; Dinoprostone; Enzyme Activation; Microglia; Protein Kinase C; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Tetradecanoylphorbol Acetate | 2000 |
Genistein augments prostaglandin-induced recovery of barrier function in ischemia-injured porcine ileum.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chlorides; Cyclic GMP; Dinoprostone; Drug Synergism; Electric Impedance; Female; Genistein; Ileum; Intestinal Mucosa; Ischemia; Male; Mannitol; N-Formylmethionine Leucyl-Phenylalanine; Swine; Tetradecanoylphorbol Acetate; Tritium | 2000 |
Characterization of the amnion-derived AV3 cell line for use as a model for investigation of prostaglandin-cytokine interactions in human amnion.
Topics: Amnion; Cell Line; Cyclooxygenase 2; Cytokines; Dinoprostone; Epidermal Growth Factor; Humans; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
Ursolic acid inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.
Topics: Blotting, Northern; Breast; Carcinoma, Squamous Cell; Cell Line; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Plasmids; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; RNA, Ribosomal, 18S; Signal Transduction; Tetradecanoylphorbol Acetate; Tongue Neoplasms; Transcription, Genetic; Transfection; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2000 |
Feedback control of cyclooxygenase-2 expression through PPARgamma.
Topics: Animals; Aorta; Cattle; Cell Differentiation; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Endothelium, Vascular; Feedback; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Isoenzymes; Kinetics; Lipopolysaccharides; Luciferases; Macrophages; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; U937 Cells | 2000 |
Prostaglandin E2 induces expression of P-selectin (CD62P) on cultured human umbilical vein endothelial cells and enhances endothelial binding of CD4-T-cells.
Topics: CD4-Positive T-Lymphocytes; Cell Adhesion; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Histamine; Humans; P-Selectin; Tetradecanoylphorbol Acetate; Umbilical Veins | 2000 |
Phorbol ester stimulates cyclooxygenase-2 expression and prostanoid production in cardiac myocytes.
Topics: Animals; Animals, Newborn; Cell Division; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Isoenzymes; Leucine; Mitogen-Activated Protein Kinases; Myocardium; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Cyclooxygenase regulates human oropharyngeal carcinomas via the proinflammatory cytokine IL-6: a general role for inflammation?
Topics: Animals; Antibodies; Arachidonic Acid; Cell Division; Clinical Trials, Phase II as Topic; Culture Media, Conditioned; Cyclooxygenase Inhibitors; Dinoprostone; DNA-Binding Proteins; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Inflammation; Interleukin-1; Interleukin-6; Interleukin-8; Isoenzymes; Ketorolac; Mice; Mice, Inbred BALB C; Models, Biological; Oropharyngeal Neoplasms; Paracrine Communication; Prostaglandin-Endoperoxide Synthases; Receptors, Interleukin-6; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured | 2000 |
The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF-kappaB.
Topics: Arachidonic Acid; Biotransformation; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA-Binding Proteins; Enzyme Induction; Humans; I-kappa B Proteins; Isoenzymes; Macrophages; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Nicotiana; Nitrosamines; Plants, Toxic; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; U937 Cells | 2000 |
Usefulness of grading of neutrophil aggregate size by laser-light scattering technique for characterizing stimulatory and inhibitory effects of agents on aggregation.
Topics: Androstadienes; Bucladesine; Cell Aggregation; Cell Count; Cytochalasin B; Dinoprostone; Enzyme Activators; Enzyme Inhibitors; Humans; Lasers; Light; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Particle Size; Phorbol Esters; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Scattering, Radiation; Tetradecanoylphorbol Acetate; Wortmannin | 2000 |
Human vascular smooth muscle cells but not endothelial cells express prostaglandin E synthase.
Topics: Arachidonic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Interleukin-1; Intramolecular Oxidoreductases; Lipopolysaccharides; Muscle, Smooth, Vascular; Prostaglandin D2; Prostaglandin H2; Prostaglandin-E Synthases; Prostaglandins H; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saphenous Vein; Tetradecanoylphorbol Acetate; Tin Compounds; Tumor Necrosis Factor-alpha; Umbilical Veins | 2000 |
Inhibitory effect of citrus nobiletin on phorbol ester-induced skin inflammation, oxidative stress, and tumor promotion in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cell Line; Citrus; Cyclooxygenase 2; Dinoprostone; Drug Eruptions; Female; Flavones; Flavonoids; HL-60 Cells; Humans; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Macrophage Activation; Macrophages; Membrane Proteins; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Mitogenic signal of epidermal growth factor in chick embryo hepatocytes: role of PKCalpha.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Chick Embryo; Diglycerides; Dinoprostone; DNA; Down-Regulation; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Hepatocytes; Inositol 1,4,5-Trisphosphate; Isoenzymes; Mitogens; Myristic Acid; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Quinacrine; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine | 2000 |
Endothelins enhance prostaglandin (PGE(2) and PGF(2alpha)) biosynthesis and release by human luteal cells: evidence of a new paracrine/autocrine regulation of luteal function.
Topics: Antihypertensive Agents; Cells, Cultured; Chorionic Gonadotropin; Corpus Luteum; Cyclic AMP; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-3; Female; Humans; Kinetics; Oligopeptides; Piperidines; Progesterone; Tetradecanoylphorbol Acetate | 2001 |
Regulation of the IL-10 production by human T cells.
Topics: Antibodies, Monoclonal; B7-1 Antigen; Calcineurin; Calcium Signaling; CD4-Positive T-Lymphocytes; CD58 Antigens; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interferon Type I; Interleukin-10; Interleukin-12; Interleukin-2; Ionomycin; Ionophores; Leukocyte Common Antigens; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Recombinant Proteins; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Transcription Factors | 2001 |
Effects of phycocyanin extract on prostaglandin E2 levels in mouse ear inflammation test.
Topics: Animals; Arachidonic Acid; Dinoprostone; Ear, External; Edema; Indicators and Reagents; Inflammation; Male; Mice; Phospholipases A; Phospholipases A2; Phycocyanin; Tetradecanoylphorbol Acetate | 2000 |
Molecular characterization of bovine prostaglandin G/H synthase-2 and regulation in uterine stromal cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cattle; Cloning, Molecular; Cyclooxygenase 2; Dinoprostone; DNA, Complementary; Female; Gene Expression Regulation, Enzymologic; Gene Library; Isoenzymes; Molecular Sequence Data; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection; Uterus | 2001 |
Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.
Topics: Adult; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Colon; Curcumin; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Epithelial Cells; Female; Glucuronides; Hepatocytes; Humans; Intestinal Mucosa; Isoenzymes; Male; Mass Spectrometry; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Indomethacin increases 15-PGDH mRNA expression in HL60 cells differentiated by PMA.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cell Differentiation; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydroxyprostaglandin Dehydrogenases; Immunoassay; Indomethacin; Isoenzymes; Membrane Proteins; Nucleic Acid Hybridization; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes.
Topics: Animals; Arachidonic Acid; CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Cyclooxygenase 2; Cytosol; Dinoprostone; Enzyme Inhibitors; Inflammation; Isoenzymes; Keratinocytes; Keratins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Phospholipases A; Phospholipids; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Skin; Tetradecanoylphorbol Acetate | 2001 |
Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300.
Topics: Arthritis; Base Sequence; Cell Line; CREB-Binding Protein; Cyclooxygenase 2; Dinoprostone; DNA Primers; Enzyme Induction; Humans; Isoenzymes; Ligands; Membrane Proteins; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation | 2001 |
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differentiation; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dinoprostone; Drug Synergism; Enzyme Induction; Estradiol; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioma; Hybrid Cells; Hydrocortisone; Ionophores; Isoenzymes; Luciferases; Membrane Proteins; Mice; Mifepristone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 2001 |
Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte formations and experimental inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Edema; Free Radical Scavengers; Humans; Isoenzymes; Lipopolysaccharides; Luminescent Measurements; Macrophages; Membrane Proteins; Mice; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2001 |
Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER).
Topics: Animals; Cell Division; Chemokines; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cytokines; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Repressor Proteins; Second Messenger Systems; Spleen; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Transcription, Genetic | 2001 |
Stimulatory and synergistic effects of luteinising hormone and insulin like growth factor 1 on the secretion of vascular endothelial growth factor and progesterone of cultured bovine granulosa cells.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; Drug Synergism; Endothelial Growth Factors; Female; Fibroblast Growth Factor 2; Granulosa Cells; Growth Hormone; Hydrocortisone; Insulin-Like Growth Factor I; Ionophores; Luteinizing Hormone; Lymphokines; Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Drugs, Chinese Herbal; Enzyme Induction; Indomethacin; Isoenzymes; Macrophages, Peritoneal; Membrane Proteins; Oleanolic Acid; Plant Roots; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Saponins; Tetradecanoylphorbol Acetate; Triterpenes | 2001 |
Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro.
Topics: Aged; Calcitriol; Calcium Channel Agonists; Cartilage; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dinoprostone; Humans; Immunohistochemistry; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Middle Aged; Osteoarthritis, Knee; Receptors, Calcitriol; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Olive oil decreases both oxidative stress and the production of arachidonic acid metabolites by the prostaglandin G/H synthase pathway in rat macrophages.
Topics: Animals; Arachidonic Acid; Corn Oil; Dinoprostone; Fish Oils; Macrophages, Peritoneal; Male; Nitric Oxide; Olive Oil; Oxidative Stress; Plant Oils; Prostaglandin-Endoperoxide Synthases; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Human cytomegalovirus circumvents NF-kappa B dependence in retinal pigment epithelial cells.
Topics: Cells, Cultured; Cyclooxygenase 2; Cytomegalovirus; Dinoprostone; Humans; Isoenzymes; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; Pigment Epithelium of Eye; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha; Up-Regulation; Virus Replication | 2001 |
Inhibition of TPA-induced cyclooxygenase-2 expression and skin inflammation in mice by wogonin, a plant flavone from Scutellaria radix.
Topics: Animals; Antioxidants; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drugs, Chinese Herbal; Edema; Flavanones; Flavones; Flavonoids; Gene Expression; Isoenzymes; Magnoliopsida; Male; Mice; Mice, Inbred ICR; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Skin Diseases; Tetradecanoylphorbol Acetate | 2001 |
The effect of dexamethasone on expression of mitogen-induced cyclooxygenase-2 mRNA by amnion-derived (WISH) cells.
Topics: Amnion; Cell Line, Transformed; Culture Media, Conditioned; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gene Expression; Glucocorticoids; Humans; Isoenzymes; Kinetics; Membrane Proteins; Mitogens; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate | 2001 |
Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes.
Topics: Animals; Cattle; Chondrocytes; Dinoprostone; Down-Regulation; Interleukin-1; Lipopolysaccharides; Phospholipase D; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Cell signaling pathways mediating epidermal growth factor stimulation of Na:K:2Cl cotransport activity in rabbit corneal epithelial cells.
Topics: Animals; Benzofurans; Cell Division; Cell Line, Transformed; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium, Corneal; ErbB Receptors; Ethers, Cyclic; Fluorescence; Ion Transport; Kinetics; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Rabbits; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Inhibition of prostalglandin E2 production by 2'-hydoxychalcone derivatives and the mechanism of action.
Topics: Animals; Blotting, Western; Carcinogens; Chalcone; Chalcones; Cyclooxygenase 2; Dinoprostone; Isoenzymes; Macrophages, Peritoneal; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2001 |
Role of phospholipases A(2) in growth-dependent changes in prostaglandin release from 3T6 fibroblasts.
Topics: Animals; Arachidonic Acid; Cell Culture Techniques; Cell Division; Cell Line; Culture Media; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Group V Phospholipases A2; Group VI Phospholipases A2; Intracellular Membranes; Isoenzymes; Mice; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 2001 |
Phorbol 12-myristate 13-acetate triggers the protein kinase A-mediated phosphorylation and activation of the PDE4D5 cAMP phosphodiesterase in human aortic smooth muscle cells through a route involving extracellular signal regulated kinase (ERK).
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cells, Cultured; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dinoprostone; Enzyme Activation; Humans; Indomethacin; Isoenzymes; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Serine; Tetradecanoylphorbol Acetate | 2001 |
Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Breast; Cell Line, Transformed; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epithelial Cells; Humans; Isoenzymes; Luciferases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthoquinones; Plant Extracts; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2001 |
Conjugated polyhydroxybenzene derivatives block tumor necrosis factor-alpha-mediated nuclear factor-kappaB activation and cyclooxygenase-2 gene transcription by targeting IkappaB kinase activity.
Topics: Anti-Inflammatory Agents; Benzofurans; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; DNA; DNA-Binding Proteins; Enzyme Activation; Humans; I-kappa B Kinase; I-kappa B Proteins; Isoenzymes; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Pyridines; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells.
Topics: Bucladesine; Cell Differentiation; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Histamine; Humans; Isoquinolines; Macrophages; Monocytes; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Up-Regulation | 2001 |
New insights into the mechanism of action of the anti-inflammatory triterpene lupeol.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cytokines; Dinoprostone; Dose-Response Relationship, Drug; Edema; Inflammation; Interleukin-1; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Models, Animal; Nitrites; Pentacyclic Triterpenes; Phytotherapy; Pimenta; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Necrosis Factor-alpha | 2001 |
Inhibitory effect of menaquinone-7 (vitamin K2) on osteoclast-like cell formation and osteoclastic bone resorption in rat bone tissues in vitro.
Topics: Animals; Bone and Bones; Bone Marrow Cells; Bone Resorption; Bucladesine; Calcitonin; Calcium; Carcinogens; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Hemostatics; Male; Osteoclasts; Oxytocics; Peptide Fragments; Rats; Rats, Wistar; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate; Vitamin K 2 | 2001 |
Effects of naturally occurring isoflavones on prostaglandin E2 production.
Topics: Animals; Dinoprostone; Fabaceae; Iridaceae; Isoflavones; Macrophages, Peritoneal; Male; Molecular Structure; Plant Extracts; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2002 |
Regulation of urea permeability in frog urinary bladder by prostaglandin E(2).
Topics: Algorithms; Animals; Biological Transport, Active; Cyclic AMP; Dinoprostone; In Vitro Techniques; Indicators and Reagents; Isoquinolines; Male; Osmolar Concentration; Phloretin; Rana temporaria; Receptors, Prostaglandin; Sulfonamides; Tetradecanoylphorbol Acetate; Urea; Urinary Bladder; Vasotocin | 2002 |
Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alopecia; Animals; Carcinogens; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Hair Follicle; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; Phenotype; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 2002 |
Effects of platelet activating factor, butyrate and interleukin-6 on cyclooxygenase-2 expression in human esophageal cancer cells.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Esophageal Neoplasms; Female; Humans; Immunohistochemistry; Interleukin-6; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Death; Cell Differentiation; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA Adducts; Female; Immunohistochemistry; Isoenzymes; Keratinocytes; Membrane Proteins; Mice; Mice, Inbred C57BL; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent.
Topics: Animals; Arachidonic Acids; Calcium; Calcium Channel Blockers; CHO Cells; Cricetinae; Cyclooxygenase 2; Dinoprostone; Dopamine; Dopamine Antagonists; Drug Interactions; Enzyme Inhibitors; Gallic Acid; Indomethacin; Isoenzymes; Naphthalenes; Nitrobenzenes; Phosphatidylcholines; Prostaglandin-Endoperoxide Synthases; Pyrones; Quinacrine; Receptors, Dopamine D2; Salicylamides; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2002 |
Flavanones structure-related inhibition on TPA-induced tumor promotion through suppression of extracellular signal-regulated protein kinases: involvement of prostaglandin E2 in anti-promotive process.
Topics: 3T3 Cells; Animals; Biphenyl Compounds; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Free Radical Scavengers; Gene Expression Regulation; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Phosphorylation; Picrates; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymidine | 2002 |
Involvement of Rho and p38 MAPK in endothelin-1-induced expression of PGHS-2 mRNA in osteoblast-like cells.
Topics: ADP Ribose Transferases; Animals; Botulinum Toxins; Cell Line; Cholera Toxin; Cyclooxygenase 2; Dinoprostone; Endothelin-1; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; rho GTP-Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2002 |
Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production.
Topics: Alprostadil; Animals; Bone Marrow Cells; Cell Degranulation; Cytokines; Dinoprostone; Interleukin-6; Leukotrienes; Mast Cells; Mice; Mice, Knockout; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
PGE2 reduces arachidonic acid release in murine podocytes: evidence for an autocrine feedback loop.
Topics: Animals; Antigens, Human Platelet; Arachidonic Acid; Autocrine Communication; Cell Line, Transformed; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Epithelial Cells; Feedback; Isoenzymes; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate | 2003 |
Inhibition of prostaglandin E(2) production by taiwanin C isolated from the root of Acanthopanax chiisanensis and the mechanism of action.
Topics: Animals; Arachidonic Acid; Araliaceae; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Enzyme Inhibitors; Isoenzymes; Lactones; Lignans; Macrophages, Peritoneal; Male; Membrane Proteins; Plant Roots; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 2002 |
Regulation of follistatin-related gene (FLRG) expression by protein kinase C and prostaglandin E(2) in cultured granulosa-luteal cells.
Topics: Bucladesine; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Follistatin-Related Proteins; Gene Expression Regulation; Humans; Indoles; Luteal Cells; Luteinizing Hormone; Ovary; Progesterone; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Regulation of prolactin expression in leukemic cell lines and peripheral blood mononuclear cells.
Topics: Adult; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; Ionomycin; Leukemia; Leukocytes, Mononuclear; Middle Aged; Prolactin; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Terbutaline; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor.
Topics: Acetamides; Cyclic AMP; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-2; Lymphocytes; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiazoles; Thiosemicarbazones | 2003 |
Influence of different isoforms of recombinant trophoblastic interferons on prostaglandin production in cultured bovine endometrial cells.
Topics: Animals; Blotting, Northern; Cattle; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Enzyme Induction; Epithelial Cells; Female; Interferon Type I; Isoenzymes; Oxytocin; Pregnancy Proteins; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Recombinant Proteins; Stromal Cells; Tetradecanoylphorbol Acetate | 2003 |
Inhibition of TPA-induced NF-kappaB nuclear translocation and production of NO and PGE2 by the anti-rheumatic gold compounds.
Topics: Animals; Antirheumatic Agents; Auranofin; Aurothioglucose; Cells, Cultured; Dinoprostone; Gold Sodium Thiomalate; Macrophages, Peritoneal; Male; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2003 |
Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha).
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Nitrobenzenes; Polychlorinated Dibenzodioxins; Sulfonamides; Tetradecanoylphorbol Acetate | 2003 |
Regulation of cytosolic phospholipase A2, cyclooxygenase-1 and -2 expression by PMA, TNFalpha, LPS and M-CSF in human monocytes and macrophages.
Topics: Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cytosol; Dinoprostone; Humans; Isoenzymes; Lipopolysaccharides; Macrophage Colony-Stimulating Factor; Macrophages; Membrane Proteins; Monocytes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2003 |
IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase.
Topics: Adenoviridae; Cell Line; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Interleukin-1; Intramolecular Oxidoreductases; Isoenzymes; Luminescent Proteins; Membrane Proteins; Microsomes; NF-kappa B; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 2003 |
Duplexes of 21 nucleotide RNA specific for COX II mediates RNA interference in cultured bovine aortic coronary endothelial cells (BAECs).
Topics: Animals; Aorta; Blotting, Western; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Isoenzymes; Lac Operon; Microscopy, Fluorescence; Prostaglandin-Endoperoxide Synthases; RNA Interference; RNA, Double-Stranded; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Expression of microsomal prostaglandin E synthase-1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines.
Topics: Adenocarcinoma; Blotting, Northern; Blotting, Western; Carcinogens; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Interleukin-1; Intestines; Intramolecular Oxidoreductases; Isoenzymes; Lung Neoplasms; Membrane Proteins; Microsomes; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Signal transduction for inhibition of inducible nitric oxide synthase and cyclooxygenase-2 induction by capsaicin and related analogs in macrophages.
Topics: Animals; Capsaicin; Cell Line; Cyclooxygenase 2; Dinoprostone; Diterpenes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Ganglia, Spinal; I-kappa B Kinase; Interferon-gamma; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Male; Mitogen-Activated Protein Kinases; Neurotoxins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Drug; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factor AP-1 | 2003 |
Effect of olive oil minor components on oxidative stress and arachidonic acid mobilization and metabolism by macrophages RAW 264.7.
Topics: Animals; Arachidonic Acid; Cell Line; Cyclooxygenase 2; Dinoprostone; Hydrogen Peroxide; Isoenzymes; Leukotriene B4; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Olive Oil; Oxidative Stress; Phenylethyl Alcohol; Plant Oils; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Sitosterols; Squalene; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Effects of phenacetin and its metabolite p-phenetidine on COX-1 and COX-2 activities and expression in vitro.
Topics: Cells, Cultured; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoenzymes; Leukocytes, Mononuclear; Membrane Proteins; Phenacetin; Phenetidine; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2003 |
Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.
Topics: Antibodies; Ceramides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphoserine; Protein Subunits; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2004 |
Methanolic extract of adlay seed suppresses COX-2 expression of human lung cancer cells via inhibition of gene transcription.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Coix; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gene Expression Regulation; Humans; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Methanol; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Seeds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils.
Topics: Animals; Arachidonic Acid; Calcimycin; Dietary Fats, Unsaturated; Dinoprostone; Eicosanoids; Fatty Acids; Fatty Acids, Essential; Fish Oils; gamma-Linolenic Acid; Glucuronidase; Glycogen; Hydrogen Peroxide; Inflammation; Linoleic Acid; Linoleic Acids; Lysosomes; Male; Muramidase; Neutrophils; Oenothera biennis; Oleic Acid; Olive Oil; Peritoneum; Peroxidase; Plant Oils; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase.
Topics: Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Stomach Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
Enantioselective synthesis and biological activity of (3S,4R)- and (3S,4S)-3-hydroxy-4-hydroxymethyl- 4-butanolides in relation to PGE2.
Topics: 4-Butyrolactone; Binding, Competitive; Cell Differentiation; Cell Survival; Dinoprostone; HL-60 Cells; Humans; Proto-Oncogene Proteins c-fos; Radioligand Assay; RNA, Messenger; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2004 |
Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin.
Topics: Animals; Carcinogens; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Female; Isoenzymes; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyrazoles; Skin; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions.
Topics: Analgesics; Animals; Binding Sites; Calcium; Carrageenan; Cell Movement; Cyclooxygenase 2; Dinoprostone; Dogs; Drug Interactions; Edema; Enzyme Inhibitors; Estrenes; Humans; Interleukin-8; Isoenzymes; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Membrane Proteins; Mice; Neutrophils; Peritoneal Lavage; Phospholipase C beta; Phospholipase D; Prostaglandin-Endoperoxide Synthases; Pyrrolidinones; Rats; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
The anti-inflammatory potential of berberine in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Berberine; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Indomethacin; Isoenzymes; Membrane Proteins; Mouth Neoplasms; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Up-Regulation | 2004 |
Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawal.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line, Transformed; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Myometrium; Progesterone; Receptors, Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate | 2004 |
Pro/antioxidant status in murine skin following topical exposure to cumene hydroperoxide throughout the ontogeny of skin cancer.
Topics: Animals; Antioxidants; Benzene Derivatives; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Glutathione; Humans; Inflammation; Isoenzymes; Keratinocytes; Lipid Peroxidation; Membrane Proteins; Mice; Mice, Inbred SENCAR; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Skin Neoplasms; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 2004 |
Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Carrageenan; Cell Degranulation; Cyclooxygenase 1; Cyclooxygenase 2; Cytochalasin B; Dinoprostone; Edema; Female; Gastric Mucosa; Gene Expression; Genistein; Hindlimb; Humans; Indomethacin; Isoenzymes; Korea; Leukotriene B4; Lipopolysaccharides; Macrophages, Peritoneal; Medicine, East Asian Traditional; Membrane Proteins; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pancreatic Elastase; Phosphoproteins; Phosphorylation; Phosphotyrosine; Plant Extracts; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Staurosporine; Stomach; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Carrageenan; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Edema; Female; Hindlimb; Humans; Hydroquinones; Indomethacin; Inflammation; Isoenzymes; Liver Neoplasms; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenylbutazone; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tyrphostins | 2004 |
PGE2 induces IL-1beta gene expression in mouse osteoblasts through a cAMP-PKA signaling pathway.
Topics: Adenylyl Cyclase Inhibitors; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Enzyme Inhibitors; Gene Expression; Interleukin-1; Mice; Mice, Inbred BALB C; Osteoblasts; Plasmids; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG).
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cuba; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ear, External; Edema; Eicosanoids; Indomethacin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Mangifera; Mice; Oleanolic Acid; Peroxidase; Phospholipases A; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water; Xanthones | 2004 |
An anti-inflammatory role for N-acetyl aspartate in stimulated human astroglial cells.
Topics: Aniline Compounds; Anti-Inflammatory Agents; Aspartic Acid; Astrocytes; Calcium; Cell Line; Cyclooxygenase 2; Dinoprostone; Fluorescent Dyes; Humans; I-kappa B Proteins; Interleukin-1; Ionomycin; Ionophores; Isoenzymes; Membrane Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Xanthenes | 2004 |
Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules.
Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Down-Regulation; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Estrone; Gene Expression Regulation; In Vitro Techniques; Kidney Tubules, Proximal; Organic Anion Transporters, Sodium-Independent; Phenylephrine; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 2004 |
Exogenous prostaglandin E2 inhibits TPA induced matrix metalloproteinase-9 production in MCF-7 cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Collagen; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Drug Combinations; Enzyme Activation; Enzyme Induction; Humans; Laminin; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Neoplasm Metastasis; Proteoglycans; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Tetradecanoylphorbol Acetate | 2004 |
The viral protein A238L inhibits cyclooxygenase-2 expression through a nuclear factor of activated T cell-dependent transactivation pathway.
Topics: Active Transport, Cell Nucleus; Animals; Blotting, Western; Calcineurin; Calcium; Cell Nucleus; Chlorocebus aethiops; Cyclooxygenase 2; Dinoprostone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Gene Deletion; Humans; Ionophores; Isoenzymes; Jurkat Cells; Luciferases; Membrane Proteins; Microscopy, Confocal; Microscopy, Fluorescence; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Structure, Tertiary; Response Elements; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Transfection; Vero Cells; Viral Proteins | 2004 |
Antitumor promotional effects of a novel intestinal bacterial metabolite (IH-901) derived from the protopanaxadiol-type ginsenosides in mouse skin.
Topics: Animals; Antineoplastic Agents; Bacteria; Benz(a)Anthracenes; Carcinogens; Cyclooxygenase 2; Dinoprostone; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Ginsenosides; Mice; Mice, Inbred ICR; NF-kappaB-Inducing Kinase; Ornithine Decarboxylase; Papilloma; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sapogenins; Skin; Tetradecanoylphorbol Acetate | 2005 |
Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways.
Topics: Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; Humans; Membrane Proteins; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Proto-Oncogene Proteins c-raf; ras Proteins; Respiratory Mucosa; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2005 |
Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radix.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drugs, Chinese Herbal; Flavanones; Gene Expression Regulation; Interleukin-1; Membrane Proteins; Mice; NIH 3T3 Cells; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Scutellaria; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Effect of prostaglandin E2 on PMA-induced macrophage differentiation.
Topics: Cell Adhesion; Cell Differentiation; Colforsin; Dinoprostone; HL-60 Cells; Humans; Macrophages; Matrix Metalloproteinase 9; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Methotrexate suppresses inflammatory agonist induced interleukin 6 synthesis in osteoblasts.
Topics: 3T3 Cells; Animals; Antirheumatic Agents; Carcinogens; Cells, Cultured; Dinoprost; Dinoprostone; Drug Interactions; Interleukin-1; Interleukin-17; Interleukin-6; Methotrexate; Mice; Osteoblasts; Prostaglandin D2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2005 |
Prostaglandins E(2) and F(2alpha) enhance differentiation of cementoblastic cells.
Topics: Calcification, Physiologic; Cell Line, Transformed; Dental Cementum; Dinoprost; Dinoprostone; Humans; MAP Kinase Signaling System; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Tetradecanoylphorbol Acetate | 2005 |
Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1beta and TNF-alpha induced production of inflammatory mediators.
Topics: Apoptosis; Arachidonic Acid; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chemokine CCL2; Chemokine CCL5; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Gene Expression; Humans; I-kappa B Proteins; Inflammation Mediators; Interleukin-1; Interleukin-6; Ionomycin; Membrane Proteins; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Prostaglandin-Endoperoxide Synthases; Protein Precursors; RNA, Small Interfering; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transfection; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2005 |
Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin.
Topics: Animals; Anti-Inflammatory Agents; Bidens; Caffeic Acids; Cell Line; Cell Line, Tumor; Cell Survival; Chemical Fractionation; Cyclooxygenase Inhibitors; Dinoprostone; Drugs, Chinese Herbal; Gene Expression Regulation, Enzymologic; Humans; Mice; NF-kappa B; Nitric Oxide; Skin; Tetradecanoylphorbol Acetate | 2005 |
Inhibition of TPA-induced cyclooxygenase-2 (COX-2) expression by apigenin through downregulation of Akt signal transduction in human keratinocytes.
Topics: Apigenin; Cell Line; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme Activation; Humans; Keratinocytes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Antigens, CD; Calcimycin; Carcinogens; CD8-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Dinoprostone; Humans; Ionophores; Lymphocyte Activation; MAP Kinase Signaling System; NF-kappa B; Oxytocics; Protein Kinases; Receptors, Adrenergic, beta-2; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 2006 |
Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells.
Topics: Aminophenols; Blotting, Northern; Blotting, Western; Cell Line, Tumor; Chromones; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lithium Chloride; Maleimides; Models, Biological; Models, Statistical; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection | 2006 |
Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target.
Topics: Active Transport, Cell Nucleus; Catechols; Cell Line; Cell Movement; Cyclooxygenase 2; Diarylheptanoids; Dinoprostone; Epithelial Cells; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Mammary Glands, Human; Matrix Metalloproteinase 9; Membrane Proteins; Molecular Structure; NF-kappa B; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation | 2006 |
Inhibitory effects of black tea theaflavin derivatives on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and arachidonic acid metabolism in mouse ears.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Biflavonoids; Catechin; Dinoprostone; Drug Synergism; Ear; Edema; Female; Gallic Acid; Inflammation; Interleukin-1; Interleukin-6; Leukotriene B4; Lipoxygenase; Mice; Prostaglandin-Endoperoxide Synthases; Sulindac; Tea; Tetradecanoylphorbol Acetate | 2006 |
Natural nutrient mixture effectively reduces collagen matrix contraction driven by human uterine smooth muscle cells.
Topics: Animals; Cell Culture Techniques; Cells, Cultured; Collagen Type I; Dinoprostone; Estradiol; Female; Flavonoids; Humans; Lipopolysaccharides; Matrix Metalloproteinases; Myocytes, Smooth Muscle; Oxytocin; Potassium Chloride; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uterine Contraction | 2006 |
Involvement of tumor necrosis factor (TNF)-alpha in phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced skin edema in mice.
Topics: Animals; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Etanercept; Immunoglobulin G; Mice; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Antinociceptive properties produced by the pregnane compound velutinol A isolated from Mandevilla velutina.
Topics: Analgesics; Animals; Apocynaceae; Bradykinin; Capsaicin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Diterpenes; Male; Mice; Pain Measurement; Plant Extracts; Pregnanes; Tetradecanoylphorbol Acetate | 2006 |
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.
Topics: Breast Neoplasms; Cell Line, Tumor; Collagen; Cyclooxygenase 2; Cyclosporine; Dinoprostone; Drug Combinations; Humans; Ionomycin; Ionophores; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; NFATC Transcription Factors; Proteoglycans; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2006 |
Differential modulation of cyclooxygenase-mediated prostaglandin production by the putative cancer chemopreventive flavonoids tricin, apigenin and quercetin.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flavonoids; HT29 Cells; Humans; Intramolecular Oxidoreductases; Models, Biological; Molecular Structure; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Quercetin; Sheep; Tetradecanoylphorbol Acetate | 2006 |
Response of human macrophage-like cells to stimulation by Fusobacterium nucleatum ssp. nucleatum lipopolysaccharide.
Topics: Apoptosis; Cytokines; Dinoprostone; Fusobacterium nucleatum; Humans; Lipopolysaccharides; Macrophages; Matrix Metalloproteinase 9; Monocytes; Nitric Oxide; Periodontitis; Phospholipases; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation | 2006 |
Gene expression of arachidonate cyclooxygenase pathway leading to the delayed synthesis of prostaglandins E2 and F2alpha in response to phorbol 12-myristate 13-acetate and action of these prostanoids during life cycle of adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Calcimycin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Gene Expression Regulation, Enzymologic; Humans; Ionophores; Mice; Protein Isoforms; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triglycerides | 2006 |
Protective effects of a standard extract of Mangifera indica L. (VIMANG) against mouse ear edemas and its inhibition of eicosanoid production in J774 murine macrophages.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprostone; Dose-Response Relationship, Drug; Edema; Eicosanoids; Interferon-gamma; Ionophores; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Mangifera; Mice; Mice, Inbred Strains; Phytotherapy; Plant Bark; Plant Extracts; Tetradecanoylphorbol Acetate | 2006 |
Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells.
Topics: Cell Separation; Cell Survival; Coculture Techniques; Cytokines; Dendritic Cells; Depression, Chemical; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Interferon Type I; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-4; Lipopolysaccharides; Poly I-C; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Th1 Cells | 2006 |
Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells.
Topics: Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Cell Proliferation; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Fluorescent Antibody Technique; Gastric Mucosa; Male; Protein Kinases; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2006 |
Inhibition of chronic skin inflammation by topical anti-inflammatory flavonoid preparation, Ato Formula.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drug Eruptions; Flavonoids; Gene Expression Regulation; Interleukin-1; Male; Mice; Mice, Inbred ICR; Plant Extracts; Prednisolone; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Cyclooxygenase-2 expression in normal and neoplastic canine mammary cell lines.
Topics: Animals; Cell Line; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Dog Diseases; Dogs; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Animal; Tetradecanoylphorbol Acetate | 2006 |
Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells.
Topics: Animals; Antigens, CD19; B-Lymphocyte Subsets; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Cell Line; Concanavalin A; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Induction; HeLa Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Macrophages; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Processing, Post-Translational; Receptors, Antigen, T-Cell; Signal Transduction; STAT5 Transcription Factor; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tryptophan | 2007 |
Selenium regulates cyclooxygenase-2 and extracellular signal-regulated kinase signaling pathways by activating AMP-activated protein kinase in colon cancer cells.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Growth Processes; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Interactions; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; HT29 Cells; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Multienzyme Complexes; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Ribonucleotides; Selenic Acid; Selenium Compounds; Tetradecanoylphorbol Acetate | 2006 |
The effects of phorbol 12-myristate 13-acetate, cholera toxin, prostaglandin E2 and norepinephrine on inducible nitric oxide synthase activation induced by lipopolysaccharide in C6 cells.
Topics: Animals; Cell Line, Tumor; Cholera Toxin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Glioma; Humans; Lipopolysaccharides; Nitric Oxide Synthase Type II; Norepinephrine; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Concomitant activation of extracellular signal-regulated kinase and induction of COX-2 stimulates maximum prostaglandin E2 synthesis in human airway epithelial cells.
Topics: Calcimycin; Calcium; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-1beta; Ionophores; Kinetics; Lipopolysaccharides; Phospholipases A; Phosphorylation; Pneumonia; Protein Kinase C; Respiratory System; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Mechanisms underlying the inhibitory actions of the pentacyclic triterpene alpha-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Dermatitis, Contact; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Male; MAP Kinase Signaling System; Membrane Proteins; Mice; NF-kappa B; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Skin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA | 2007 |
Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drug Interactions; Female; Inflammation; Lipopolysaccharides; Mice; Nitric Oxide Synthase Type II; Nitrites; Oxidation-Reduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thioctic Acid | 2007 |
Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Dinoprostone; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocics; Receptors, G-Protein-Coupled; Sciatic Nerve; Signal Transduction; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endometrium; Female; Indoles; Maleimides; Paracrine Communication; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Stromal Cells; Tetradecanoylphorbol Acetate | 2007 |
Anti-inflammatory activity of sertaconazole nitrate is mediated via activation of a p38-COX-2-PGE2 pathway.
Topics: Acne Vulgaris; Animals; Anti-Inflammatory Agents; Antifungal Agents; Biopsy; Carcinogens; Cell Line; Cyclooxygenase 2; Cytokines; Dermatitis, Contact; Dinoprostone; Enzyme Activation; Gram-Positive Bacterial Infections; Humans; Imidazoles; Irritants; Keratinocytes; Leukocytes, Mononuclear; Mice; p38 Mitogen-Activated Protein Kinases; Propionibacterium acnes; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Thiophenes | 2008 |
Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is mediated by phospholipase D isozymes in human astroglioma cells.
Topics: Astrocytoma; Cell Hypoxia; Cobalt; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Lipopolysaccharides; Pertussis Toxin; Phospholipase D; Phospholipases A2; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Up-Regulation | 2007 |
Effects of naturally occurring dihydroflavonols from Inula viscosa on inflammation and enzymes involved in the arachidonic acid metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cell Survival; Dinoprostone; Edema; Female; Flavonols; Histamine Release; Humans; In Vitro Techniques; Inflammation; Inula; Leukocyte Elastase; Leukotriene B4; Mice; Neutrophils; Peroxidase; Phospholipases A; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2007 |
Assessment of anti-inflammatory and antinociceptive activities of Daphne pontica L. (Thymelaeaceae).
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzoquinones; Carrageenan; Colic; Daphne; Dinoprostone; Ear, External; Edema; Flowers; Hindlimb; Male; Medicine, Traditional; Methanol; Mice; Plant Extracts; Plant Leaves; Plant Roots; Plant Stems; Tetradecanoylphorbol Acetate; Time Factors; Turkey | 2007 |
Prostanoids induce egr1 gene expression in cementoblastic OCCM cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Line; Colforsin; Dental Cementum; Dinoprost; Dinoprostone; Early Growth Response Protein 1; Enzyme Activators; Gene Expression Regulation; Ionomycin; Ionophores; Mice; Prostaglandins; Prostaglandins F, Synthetic; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Zinc Fingers | 2007 |
Valuation of anti-inflammatory and antinociceptive activities of Erica species native to Turkey.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Dinoprostone; Ericaceae; Male; Mice; Plant Extracts; Tetradecanoylphorbol Acetate; Turkey | 2008 |
Topical transduction of superoxide dismutase mediated by HIV-1 Tat protein transduction domain ameliorates 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Cytokines; Dinoprostone; HIV-1; Humans; Inflammation; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type II; Protein Structure, Tertiary; Reactive Oxygen Species; Recombinant Fusion Proteins; Skin Diseases; Superoxide Dismutase; tat Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate | 2008 |
Sensitization of the apoptotic effect of gamma-irradiation in genistein-pretreated CaSki cervical cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Dinoprostone; Female; Gamma Rays; Gene Expression Regulation, Neoplastic; Genistein; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Uterine Cervical Neoplasms | 2008 |
Resveratrol modulates innate and inflammatory responses in fish leucocytes.
Topics: Animals; Cell Movement; Cells, Cultured; Dinoprostone; Flatfishes; Gene Expression Regulation; Immunity, Innate; Inflammation; Kidney; Leukocytes; Peroxidase; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
Development and characterization of a simian virus 40 immortalized bovine endometrial stromal cell line.
Topics: Animals; Cattle; Cell Line; Cells, Cultured; Dinoprost; Dinoprostone; Endometrium; Estrogen Receptor alpha; Female; Interferon-gamma; Prostaglandins; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Simian virus 40; Stromal Cells; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2009 |
Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1.
Topics: Animals; Antioxidants; Cell Line; Dinoprostone; Flavonoids; Humans; Mice; Phenols; Polyphenols; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Up-Regulation | 2008 |
Potent anti-inflammatory effects of two quinolinedione compounds, OQ1 and OQ21, mediated by dual inhibition of inducible NO synthase and cyclooxygenase-2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Edema; Lipopolysaccharides; Macrophages; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Quinolones; Tetradecanoylphorbol Acetate | 2009 |
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cell Survival; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Female; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide; Nitrites; Sulfones; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2009 |
Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Euphorbia; Granulocytes; Inflammation Mediators; Lanosterol; Latex; Lipopolysaccharides; Macrophages; Male; Mice; Neutrophil Infiltration; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Phytotherapy; Plant Extracts; Tetradecanoylphorbol Acetate | 2010 |
The anti-inflammatory effects of a methanolic extract from Radix Isatidis in murine macrophages and mice.
Topics: Animals; Anti-Inflammatory Agents; Brassicaceae; Cell Line; Cell Survival; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Female; I-kappa B Kinase; Inflammation; Inflammation Mediators; Interleukin-6; Lipopolysaccharides; Macrophages; Methanol; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide; Peroxidase; Plant Extracts; Plant Roots; Solvents; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
Dihydro-N-caffeoyltyramine down-regulates cyclooxygenase-2 expression by inhibiting the activities of C/EBP and AP-1 transcription factors.
Topics: Animals; Antioxidants; Caffeic Acids; CCAAT-Enhancer-Binding Proteins; Cell Line; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Lycium; Macrophages; Plant Extracts; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Tyramine | 2010 |
Ellagic acid inhibits lipopolysaccharide-induced expression of enzymes involved in the synthesis of prostaglandin E2 in human monocytes.
Topics: Calcimycin; Cyclooxygenase 2; Dinoprostone; Ellagic Acid; Humans; Intramolecular Oxidoreductases; Kinetics; Lipopolysaccharides; Microsomes; Monocytes; Phospholipases A2; Prostaglandin-E Synthases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2010 |
Transglutaminase II interacts with rac1, regulates production of reactive oxygen species, expression of snail, secretion of Th2 cytokines and mediates in vitro and in vivo allergic inflammation.
Topics: Anaphylaxis; Animals; Antigens; Cadherins; Carcinogens; Cell Line, Tumor; Cytokines; Dermatitis, Atopic; Dinoprostone; GTP-Binding Proteins; Histone Deacetylases; Inflammation; Intramolecular Oxidoreductases; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Neuropeptides; NF-kappa B; Prostaglandin-E Synthases; Protein Glutamine gamma Glutamyltransferase 2; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Th2 Cells; Transcription, Genetic; Transglutaminases | 2010 |
The licorice flavonoid isoliquiritigenin suppresses phorbol ester-induced cyclooxygenase-2 expression in the non-tumorigenic MCF-10A breast cell line.
Topics: Base Sequence; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Chalcones; Cyclooxygenase 2; Dinoprostone; DNA Primers; Electrophoretic Mobility Shift Assay; Female; Glycyrrhiza; Humans; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition in human colon cancers.
Topics: Adult; Aged; Aged, 80 and over; Blotting, Western; Cadherins; Cell Differentiation; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Epithelial Cells; Epithelium; Female; Homeodomain Proteins; HT29 Cells; Humans; Immunohistochemistry; In Vitro Techniques; Male; Mesoderm; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Tetradecanoylphorbol Acetate; Transcription Factors; Zinc Finger E-box-Binding Homeobox 1 | 2009 |
The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines.
Topics: Animals; Apigenin; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 3; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Extracellular Signal-Regulated MAP Kinases; Female; G2 Phase; Gene Expression Regulation, Enzymologic; Humans; Luciferases; Melanoma, Experimental; Mice; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2010 |
Homoisoflavanone inhibits UVB-induced skin inflammation through reduced cyclooxygenase-2 expression and NF-kappaB nuclear localization.
Topics: Animals; Arachidonic Acid; Cells, Cultured; Croton Oil; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dermatitis; Dinoprostone; Down-Regulation; Edema; Humans; Inflammation Mediators; Isoflavones; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; NF-kappa B; Reactive Oxygen Species; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2010 |
Butein downregulates phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in cancerous and non-cancerous breast cells.
Topics: Breast; Breast Neoplasms; Cell Line, Tumor; Chalcones; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 2010 |
Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Epidermis; Female; Humans; Mice; Mice, Hairless; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Up-Regulation | 2011 |
A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression.
Topics: Animals; Carbon Tetrachloride; Cryptomeria; Cyclooxygenase 2 Inhibitors; Dermatitis; Dinoprostone; Heme Oxygenase-1; Humans; Inflammation; Interleukin-6; Lipopolysaccharides; Liver Diseases; Macrophages; Mice; Nitric Oxide Synthase Type II; RNA, Messenger; Sesquiterpenes; Silymarin; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Phenethyl isothiocyanate inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory responses in mouse skin.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Inflammation; Interleukin-6; Isothiocyanates; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; NF-kappa B p50 Subunit; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Proto-Oncogene Proteins c-akt; Skin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts.
Topics: Adipose Tissue; Aromatase; Breast; Breast Neoplasms; Chromatin Immunoprecipitation; Colforsin; Dinoprostone; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Organ Specificity; Postmenopause; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection | 2011 |
15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Arachidonic Acid; Calcimycin; Cell Proliferation; Chromans; Dinoprost; Dinoprostone; Gene Expression; Ionophores; Isoenzymes; Lipid Metabolism; Mice; NF-kappa B; PPAR gamma; Proline; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thiazolidinediones; Thiocarbamates; Triglycerides; Troglitazone | 2011 |
Comparison on the anti-inflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoyl-phorbol-13-acetate-induced ear edema in mice.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ear; Edema; Ethanol; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred ICR; Peroxidase; Phellodendron; Plant Bark; Plants, Medicinal; Reactive Oxygen Species; RNA, Messenger; Solvents; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Reciprocal regulation of NADPH oxidases and the cyclooxygenase-2 pathway.
Topics: Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Humans; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2011 |
Anti-inflammatory effect of transduced PEP-1-cyclophilin A in Raw264.7 cells and 12-O-tetradecanoylphorbol-13-acetate-induced mice.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cyclooxygenase 2; Cyclophilin A; Cytokines; Dinoprostone; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Inflammation; Macrophages; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Peptide Hydrolases; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2011 |
Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition.
Topics: Catechin; Celecoxib; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Screening Assays, Antitumor; Epithelial-Mesenchymal Transition; Humans; Melanoma; Neoplasm Invasiveness; NF-kappa B; Pyrazoles; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides; Tea; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2011 |
Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent.
Topics: Animals; Bone and Bones; Carcinogens; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Early Growth Response Protein 2; Female; Insulin-Like Growth Factor I; Integrin beta1; Integrin beta3; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Receptors, Prostaglandin E, EP1 Subtype; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation; Wnt Signaling Pathway; Wnt3A Protein | 2012 |
Prostaglandin modulation of phorbol ester skin tumor promotion.
Topics: Animals; Arachidonic Acid; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dinoprost; Dinoprostone; Female; Mice; Mice, Inbred SENCAR; Oxytocics; Papilloma; Prostaglandins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Dose-dependent effect of resveratrol on bladder cancer cells: chemoprevention and oxidative stress.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Cell Line, Tumor; Dinoprostone; Dose-Response Relationship, Drug; Humans; Neutrophils; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 2012 |
Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages.
Topics: Alkaloids; Animals; Benzodioxoles; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Cell Line; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme Activation; Humans; Macrophages; Mice; NF-kappa B; Piperidines; Polyunsaturated Alkamides; Protein Kinases; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2012 |
Effect of Rhizoma Polygonati on 12-O-tetradecanoylphorbol-acetate-induced ear edema in mice.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Dinoprostone; Ear; Edema; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Phytotherapy; Plant Extracts; Polygonatum; Rhizome; RNA, Messenger; Tetradecanoylphorbol Acetate | 2012 |
Macelignan inhibits histamine release and inflammatory mediator production in activated rat basophilic leukemia mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Cell Degranulation; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Histamine Release; Hypersensitivity; Inflammation Mediators; Interleukin-13; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Leukemia, Basophilic, Acute; Leukotriene C4; Lignans; Mast Cells; Myristica; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2012 |
Anti-tumor-promoting activities of agaro-oligosaccharides on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Antineoplastic Agents; Carcinogens; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Edema; Humans; Intramolecular Oxidoreductases; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitrites; Oligosaccharides; Prostaglandin-E Synthases; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Cross talk between PKC and CREB in the induction of COX-2 by PGF2α in human amnion fibroblasts.
Topics: Amnion; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dinoprost; Dinoprostone; Female; Fibroblasts; Humans; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Receptors, Prostaglandin; Signal Transduction; Tetradecanoylphorbol Acetate | 2012 |
Effect of olive oil phenols on the production of inflammatory mediators in freshly isolated human monocytes.
Topics: Anti-Inflammatory Agents; Cell Survival; Cyclooxygenase 2; Dinoprostone; Humans; Monocytes; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Pyrans; Reactive Oxygen Species; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chalcones; Cyclooxygenase 2; Dinoprostone; Ear; Edema; Inflammation Mediators; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2013 |
Upregulation of COX-2 in the lung cancer promotes overexpression of multidrug resistance protein 4 (MRP4) via PGE2-dependent pathway.
Topics: Animals; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; DNA, Complementary; Humans; Lung Neoplasms; Male; Mice; Multidrug Resistance-Associated Proteins; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Up-Regulation | 2014 |
Topical (+)-catechin emulsified gel prevents DMBA/TPA-induced squamous cell carcinoma of the skin by modulating antioxidants and inflammatory biomarkers in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Administration, Topical; Animals; Antioxidants; Biomarkers; Carcinoma, Squamous Cell; Catechin; Dinoprostone; Drug Evaluation, Preclinical; Emulsions; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
In silico target fishing for the potential bioactive components contained in Huanglian Jiedu Tang (HLJDD) and elucidating molecular mechanisms for the treatment of sepsis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Berberine; Dinoprostone; Drugs, Chinese Herbal; Humans; KB Cells; Platelet Membrane Glycoproteins; Protein Transport; Receptors, G-Protein-Coupled; Receptors, Thromboxane A2, Prostaglandin H2; Sepsis; Tetradecanoylphorbol Acetate | 2015 |
Synthesis, Anti-inflammatory Activities and Mechanisms of 3,5- dihydroxycinnamic Acid Derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cell Line; Cell Line, Tumor; Cell Survival; Cinnamates; Cyclooxygenase 2; Cytokines; Dinoprostone; Ear; Edema; Female; Lipopolysaccharides; Lipoxygenase Inhibitors; Mice, Inbred BALB C; Peroxidase; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 2015 |
Opuntia dillenii cladode: Opuntiol and opuntioside attenuated cytokines and eicosanoids mediated inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Capillary Permeability; Carrageenan; Coumaric Acids; Cytokines; Dinoprostone; Ear; Edema; Female; Foot; Leukotriene B4; Male; Mice; Monosaccharides; Neutrophils; Opuntia; Peritonitis; Phospholipases A2; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2016 |
Potent Anti-inflammatory and Analgesic Actions of the Chloroform Extract of Dendropanax morbifera Mediated by the Nrf2/HO-1 Pathway.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Araliaceae; Chloroform; Cytokines; Dinoprostone; Ear; Edema; Heme Oxygenase-1; Male; MAP Kinase Kinase 4; Membrane Proteins; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; NF-kappa B; Nitrites; Pain; Phytotherapy; Plant Extracts; Plant Leaves; RAW 264.7 Cells; Solvents; Tetradecanoylphorbol Acetate | 2016 |
A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells.
Topics: Animals; Autocrine Communication; Dinoprostone; Feedback, Physiological; Female; Gene Expression Regulation; Genes, Reporter; Granulosa Cells; Luciferases; Mice; Microsomes; Norgestrel; Primary Cell Culture; Progesterone; Promoter Regions, Genetic; Prostaglandin-E Synthases; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
EXPRESS: F-actin links Epac-PKC signaling to purinergic P2X3 receptors sensitization in dorsal root ganglia following inflammation.
Topics: Actins; Adenosine Triphosphate; Animals; Cell Membrane; Cyclic AMP; Cytochalasin D; Dinoprostone; Freund's Adjuvant; Ganglia, Spinal; Guanine Nucleotide Exchange Factors; Hyperalgesia; Inflammation; Male; Neurons; Protein Kinase C; Rats, Sprague-Dawley; Receptors, Purinergic P2X3; Signal Transduction; Tetradecanoylphorbol Acetate; Thionucleotides | 2016 |
A newly synthesized macakurzin C-derivative attenuates acute and chronic skin inflammation: The Nrf2/heme oxygenase signaling as a potential target.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Cell Line; Chronic Disease; Dermatitis, Atopic; Dinoprostone; Flavonoids; Heme Oxygenase-1; Humans; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Oxazolone; RAW 264.7 Cells; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2016 |
Essential oil of Artemisia argyi suppresses inflammatory responses by inhibiting JAK/STATs activation.
Topics: Animals; Anti-Inflammatory Agents; Artemisia; Cyclooxygenase 2; Cytokines; Dinoprostone; Edema; Janus Kinase Inhibitors; Janus Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Oils, Volatile; RAW 264.7 Cells; Reactive Oxygen Species; STAT Transcription Factors; Tetradecanoylphorbol Acetate | 2017 |
Gene Deletion of Microsomal Prostaglandin E Synthase-1 Suppresses Chemically Induced Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cyclooxygenase 2; Cytokines; Dinoprostone; Mice; Mice, Inbred BALB C; Prostaglandin-E Synthases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2021 |
Prostaglandin E2 receptor 3 promotes M1 macrophages polarization in unexplained recurrent pregnancy loss.
Topics: Abortion, Habitual; Dinoprostone; Female; Humans; Interleukin-6; Macrophages; Pregnancy; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Tetradecanoylphorbol Acetate | 2022 |